Antibody data
- Antibody Data
- Antigen structure
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- Product number
- DCABH-4449 - Provider product page
- Provider
- Creative Diagnostics
- Proper citation
- Creative Diagnostics Cat#DCABH-4449, RRID:AB_2478222
- Product name
- Rabbit Anti-Human CREB monoclonal antibody, clone 4I9M26
- Antibody type
- Monoclonal
- Description
- CREB (cAMP responsive element binding protein) encodes for a 43 kDa protein transcription factor and belongs to leucine zipper family. CREB binds to the cyclic-AMP response element (CRE, a sequence present in many viral and cellular promoters) as a homodimer. Phosphorylated form of CREB act as an inducer of transcription for the genes, upon hormone dependent stimulation of cyclic-AMP pathway. CREB is known to play important role in circadian rythm generation and memory formation
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