HPA040143

antibody from Atlas Antibodies

Targeting: ACOD1 CAD, IRG1

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA040143

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA040143, RRID:AB_10793916

Product name

Anti-IRG1

Antibody type

Polyclonal

Description

Affinity purified using the PrEST antigen as affinity ligand

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

FPAHLSTHWVADAAASVRKHLVAERALLPTDYIKR
IVLRIPNVQYVNRPFPVSEHEARHSFQYVACAMLL
DGGITVPSFHECQINRPQVRELLSKVELEY


Isotype

IgG

Vial size

100 µl

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

References

Submitted references

Pro-inflammatory Macrophages Sustain Pyruvate Oxidation through Pyruvate Dehydrogenase for the Synthesis of Itaconate and to Enable Cytokine Expression

Meiser J, Krämer L, Sapcariu S, Battello N, Ghelfi J, D'Herouel A, Skupin A, Hiller K
Journal of Biological Chemistry 2016;291(8):3932-3946

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IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid

Zamboni D, Naujoks J, Tabeling C, Dill B, Hoffmann C, Brown A, Kunze M, Kempa S, Peter A, Mollenkopf H, Dorhoi A, Kershaw O, Gruber A, Sander L, Witzenrath M, Herold S, Nerlich A, Hocke A, van Driel I, Suttorp N, Bedoui S, Hilbi H, Trost M, Opitz B
PLOS Pathogens 2016;12(2):e1005408

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Gene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in Mammalian Macrophages

Passos G, Tallam A, Perumal T, Antony P, Jäger C, Fritz J, Vallar L, Balling R, del Sol A, Michelucci A
PLOS ONE 2016;11(2):e0149050