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- Antibody Data
- Antigen structure
- References [173]
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- Product number
- 17785-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17785-1-AP, RRID:AB_2271365
- Product name
- Synaptophysin antibody
- Antibody type
- Polyclonal
- Description
- Synaptophysin antibody (Cat. #17785-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Enriched oxygen improves age-related cognitive impairment through enhancing autophagy.
Thy1-ApoE4/C/EBPβ double transgenic mice act as a sporadic model with Alzheimer's disease.
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
Effects of autotaxin and lysophosphatidic acid deficiencies on depression-like behaviors in mice exposed to chronic unpredictable mild stress.
Hallmark Molecular and Pathological Features of POLG Disease are Recapitulated in Cerebral Organoids.
Purinergic Astrocyte Signaling Driven by TNF-α After Cannabidiol Administration Restores Normal Synaptic Remodeling Following Traumatic Brain Injury.
Gut Microbiota Mediate the Neuroprotective Effect of Oolong Tea Polyphenols in Cognitive Impairment Induced by Circadian Rhythm Disorder.
PAX6 promotes neuroendocrine phenotypes of prostate cancer via enhancing MET/STAT5A-mediated chromatin accessibility.
The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics in response to netrin-1.
Bilirubin impairs neuritogenesis and synaptogenesis in NSPCs by downregulating NMDAR-CREB-BDNF signaling.
Bavachin ameliorates neuroinflammation and depressive-like behaviors in streptozotocin-induced diabetic mice through the inhibition of PKCδ.
Dietary Restriction Improves Perioperative Neurocognitive Disorders by Inhibiting Neuroinflammation and Gut Microbial Dysbiosis.
Volatile oil of Angelica sinensis Radix improves cognitive function by inhibiting miR-301a-3p targeting Ppp2ca in cerebral ischemia mice.
Periplaneta Americana (L.) extract activates the ERK/CREB/BDNF pathway to promote post-stroke neuroregeneration and recovery of neurological functions in rats.
Brassisterol A, a new ergosterol from co-cultivation of fungi attenuates neuroinflammation via targeting NLRP3/caspase-1/GSDMD pathway.
YTHDF3 modulates the Cbln1 level by recruiting BTG2 and is implicated in the impaired cognition of prenatal hypoxia offspring.
GR/Ahi1 regulates WDR68-DYRK1A binding and mediates cognitive impairment in prenatally stressed offspring.
The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics.
Prednisolone improves hippocampal regeneration after trimethyltin-induced neurodegeneration in association with prevention of T lymphocyte infiltration.
Safranal acts as a neurorestorative agent in rats with cerebral ischemic stroke via upregulating SIRT1.
Microglial Ffar4 deficiency promotes cognitive impairment in the context of metabolic syndrome.
Psoralen protects neurons and alleviates neuroinflammation by regulating microglial M1/M2 polarization via inhibition of the Fyn-PKCδ pathway.
GDF1 ameliorates cognitive impairment induced by hearing loss.
Exercise attenuates the perioperative neurocognitive disorder induced by hyperhomocysteinemia in mice.
Butyrate reduction and HDAC4 increase underlie maternal high fructose-induced metabolic dysfunction in hippocampal astrocytes in female rats.
Huanglian Jiedu decoction alleviates neurobehavioral damage in mice with chronic alcohol exposure through the RAS-RAF-MEK-ERK pathway.
Agomirs upregulating carboxypeptidase E expression rescue hippocampal neurogenesis and memory deficits in Alzheimer's disease.
The Involvement of Progranulin for α-Synuclein Reduction through Autolysosome Formation.
Periventricular Microglia Polarization and Morphological Changes Accompany NLRP3 Inflammasome-Mediated Neuroinflammation after Hypoxic-Ischemic White Matter Damage in Premature Rats.
Dietary High-Fat Promotes Cognitive Impairment by Suppressing Mitophagy.
Huperzine A-Liposomes Efficiently Improve Neural Injury in the Hippocampus of Mice with Chronic Intermittent Hypoxia.
A single intranasal dose of human mesenchymal stem cell-derived extracellular vesicles after traumatic brain injury eases neurogenesis decline, synapse loss, and BDNF-ERK-CREB signaling.
Dysfunction of inhibitory interneurons contributes to synaptic plasticity via GABABR-pNR2B signaling in a chronic migraine rat model.
Neuroprotective Effects of Leptin on the APP/PS1 Alzheimer's Disease Mouse Model: Role of Microglial and Neuroinflammation.
Neuroprotective effect of salidroside on hippocampal neurons in diabetic mice via PI3K/Akt/GSK-3β signaling pathway.
Chronic Kidney Disease Induces Cognitive Impairment in the Early Stage.
Clemastine fumarate attenuates tauopathy and meliorates cognition in hTau mice via autophagy enhancement.
Electroacupuncture alleviates PTSD-like behaviors by modulating hippocampal synaptic plasticity via Wnt/β-catenin signaling pathway.
CNTN1 Aggravates Neuroinflammation and Triggers Cognitive Deficits in Male Mice by Boosting Crosstalk between Microglia and Astrocytes.
The role of EndophilinA1 in chronic unpredicted mild stress-induced depression model mice.
ChemR23 activation attenuates cognitive impairment in chronic cerebral hypoperfusion by inhibiting NLRP3 inflammasome-induced neuronal pyroptosis.
The yeast prion protein Sup35 initiates α-synuclein pathology in mouse models of Parkinson's disease.
The yeast protein Ure2p triggers Tau pathology in a mouse model of tauopathy.
Inhibition of RhoA/ROCK signalling pathway activity improves neural damage and cognitive deficits in the fluorosis model.
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway.
Integrin β1/FAK/SRC signal pathway is involved in autism spectrum disorder in Tspan7 knockout rats.
Bilirubin Induces A1-Like Reactivity of Astrocyte.
Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.
Prenatal alcohol exposure enhanced alcohol preference and susceptibility to PTSD in a sex-dependent manner through the synaptic HCN1 channel.
Polydatin Alleviates Chronic Stress-Induced Depressive and Anxiety-like Behaviors in a Mouse Model.
Magnify is a universal molecular anchoring strategy for expansion microscopy.
Exposure to bisphenol A induces neurotoxicity associated with synaptic and cytoskeletal dysfunction in neuro-2a cells.
Gut Microbiota Taxon-Dependent Transformation of Microglial M1/M2 Phenotypes Underlying Mechanisms of Spatial Learning and Memory Impairment after Chronic Methamphetamine Exposure.
Islet amyloid polypeptide triggers α-synuclein pathology in Parkinson's disease.
SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes.
FTO-dependent m(6)A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke.
Atmospheric particulate matter impairs cognition by modulating synaptic function via the nose-to-brain route.
Tunicamycin induces depression-like behaviors in male rats, accompanied by initiated chaperon-mediated autophagy and decreased synaptic protein expression in the hippocampus.
Infralimbic YTHDF1 is necessary for the beneficial effects of acute mild exercise on auditory fear extinction retention.
Copper Induces Cognitive Impairment in Mice via Modulation of Cuproptosis and CREB Signaling.
Aerobic glycolysis is the predominant means of glucose metabolism in neuronal somata, which protects against oxidative damage.
Ginsenoside Rb1 protects hippocampal neurons in depressed rats based on mitophagy-regulated astrocytic pyroptosis.
Extracellular vesicles from hiPSC-NSCs can prevent peripheral inflammation-induced cognitive dysfunction with inflammasome inhibition and improved neurogenesis in the hippocampus.
Gypenoside IX restores Akt/GSK-3β pathway and alleviates Alzheimer's disease-like neuropathology and cognitive deficits.
Homocysteine impedes neurite outgrowth recovery after intracerebral haemorrhage by downregulating pCAMK2A.
Sirt1 Overexpression Inhibits Fibrous Scar Formation and Improves Functional Recovery After Cerebral Ischemic Injury Through the Deacetylation of 14-3-3ζ.
CNTN1 in the Nucleus Accumbens is Involved in Methamphetamine-Induced Conditioned Place Preference in Mice.
The microglial innate immune receptors TREM-1 and TREM-2 in the anterior cingulate cortex (ACC) drive visceral hypersensitivity and depressive-like behaviors following DSS-induced colitis.
The effects of acupuncture on depression by regulating BDNF-related balance via lateral habenular nucleus BDNF/TrkB/CREB signaling pathway in rats.
Aerobic Exercise Facilitates the Nuclear Translocation of SREBP2 by Activating AKT/SEC24D to Contribute Cholesterol Homeostasis for Improving Cognition in APP/PS1 Mice.
A terrified-sound stress causes cognitive impairment in female mice by impairing neuronal plasticity.
Corticostriatal Projections Relying on GABA Levels Mediate Exercise-Induced Functional Recovery in Cerebral Ischemic Mice.
Thymol improves autism-like behaviour in VPA-induced ASD rats through the Pin1/p38 MAPK pathway.
miR-6315 silencing protects against spinal cord injury through the Smo and anti-ferroptosis pathway.
Exercise training remodels inguinal white adipose tissue through adaptations in innervation, vascularization, and the extracellular matrix.
The role of reactive astrocytes in neurotoxicity induced by ultrafine particulate matter.
Peripheral Transplantation of Mesenchymal Stem Cells at Sepsis Convalescence Improves Cognitive Function of Sepsis Surviving Mice.
Treatment Combining Focused Ultrasound with Gastrodin Alleviates Memory Deficit and Neuropathology in an Alzheimer's Disease-Like Experimental Mouse Model.
Protective effect of microorganism biotransformation-produced resveratrol on the high fat diet-induced hyperlipidemia, hepatic steatosis and synaptic impairment in hamsters.
Confinement induces oxidative damage and synaptic dysfunction in mice.
Hippocampal Iron Accumulation Impairs Synapses and Memory via Suppressing Furin Expression and Downregulating BDNF Maturation.
RNF220 is an E3 ubiquitin ligase for AMPA receptors to regulate synaptic transmission.
Combined cell grafting and VPA administration facilitates neural repair through axonal regeneration and synaptogenesis in traumatic brain injury.
Profile of chimeric RNAs and TMPRSS2-ERG e2e4 isoform in neuroendocrine prostate cancer.
Evaluation of Neurotoxicity in BALB/c Mice following Chronic Exposure to Polystyrene Microplastics.
Chrysin alleviates lipopolysaccharide-induced neuron damage and behavioral deficits in mice through inhibition of Fyn.
Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice.
Dietary Salt Disrupts Tricarboxylic Acid Cycle and Induces Tau Hyperphosphorylation and Synapse Dysfunction during Aging.
Fast resupply of synaptic vesicles requires synaptotagmin-3.
Differential Expression of Secretogranins II and III in Canine Adrenal Chromaffin Cells and Pheochromocytomas.
m6A and YTHDF proteins contribute to the localization of select neuronal mRNAs.
Exercise-induced neuroprotection against cerebral ischemia/reperfusion injury is mediated via alleviating inflammasome-induced pyroptosis.
Progranulin improves neural development via the PI3K/Akt/GSK-3β pathway in the cerebellum of a VPA-induced rat model of ASD.
Heatstroke-induced late-onset neurological deficits in mice caused by white matter demyelination, Purkinje cell degeneration, and synaptic impairment in the cerebellum.
Proteomic analysis of the effects of caffeine in a neonatal rat model of hypoxic-ischemic white matter damage.
Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor.
Gestational exposure to fluoride impairs cognition in C57 BL/6 J male offspring mice via the p-Creb1-BDNF-TrkB signaling pathway.
DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors.
The circRNA circ-Nbea participates in regulating diabetic encephalopathy.
Liraglutide Alleviates Cognitive Deficit in db/db Mice: Involvement in Oxidative Stress, Iron Overload, and Ferroptosis.
Polygonatum sibiricum ameliorated cognitive impairment of naturally aging rats through BDNF-TrkB signaling pathway.
Effects of neuron autophagy induced by arsenic and fluoride on spatial learning and memory in offspring rats.
Heat shock protein Hspa13 regulates endoplasmic reticulum and cytosolic proteostasis through modulation of protein translocation.
Inhibition of BRD4 decreases fibrous scarring after ischemic stroke in rats by inhibiting the phosphorylation of Smad2/3.
FOXO3 Regulates Sevoflurane-Induced Neural Stem Cell Differentiation in Fetal Rats.
Acute lead acetate induces neurotoxicity through decreased synaptic plasticity-related protein expression and disordered dendritic formation in nerve cells.
Identification of distinct genomic features reveals frequent somatic AHNAK and PTEN mutations predominantly in primary malignant melanoma presenting in the ureter.
Traumatic Brain Injury Accelerates the Onset of Cognitive Dysfunction and Aggravates Alzheimer's-Like Pathology in the Hippocampus by Altering the Phenotype of Microglia in the APP/PS1 Mouse Model.
Nicotinamide Improves Cognitive Function in Mice With Chronic Cerebral Hypoperfusion.
Postconditioning with Sevoflurane or Propofol Alleviates Lipopolysaccharide-Induced Neuroinflammation but Exerts Dissimilar Effects on the NR2B Subunit and Cognition.
Abnormal spatiotemporal expression pattern of progranulin and neurodevelopment impairment in VPA-induced ASD rat model.
YAP drives fate conversion and chemoresistance of small cell lung cancer.
Neuroprotective effects of macamide from maca (Lepidium meyenii Walp.) on corticosterone-induced hippocampal impairments through its anti-inflammatory, neurotrophic, and synaptic protection properties.
Iptakalim alleviates synaptic damages via targeting mitochondrial ATP-sensitive potassium channel in depression.
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.
Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease.
Caloric restriction ameliorates high-fat diet induced cognitive deficits through attenuating neuroinflammation via the TREM2-PI3K/AKT signaling pathway.
Histone demethylase PHF8 drives neuroendocrine prostate cancer progression by epigenetically upregulating FOXA2.
Hippocampal LASP1 ameliorates chronic stress-mediated behavioral responses in a mouse model of unpredictable chronic mild stress.
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca(2+)-Activin A circuit in chronic cerebral hypoperfusion rats.
Haploinsufficiency of the TDP43 ubiquitin E3 ligase RNF220 leads to ALS-like motor neuron defects in the mouse.
Quantitative proteomic analysis of cortex in the depressive-like behavior of rats induced by the simulated complex space environment.
Curcumin Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behaviors via Restoring Changes in Oxidative Stress and the Activation of Nrf2 Signaling Pathway in Rats.
Xiaoyao Pills Attenuate Inflammation and Nerve Injury Induced by Lipopolysaccharide in Hippocampal Neurons In Vitro.
Transplantation of Stem Cells from Human Exfoliated Deciduous Teeth Decreases Cognitive Impairment from Chronic Cerebral Ischemia by Reducing Neuronal Apoptosis in Rats.
Bisphenol-A exposure induced neurotoxicity and associated with synapse and cytoskeleton in Neuro-2a cells.
Identification and immunohistochemical characterization of G-quadruplexes in mouse brain.
Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice.
The Neurotrophic Function of Glucagon-Like Peptide-1 Promotes Human Neuroblastoma Differentiation via the PI3K-AKT Axis.
Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells.
The critical role of the hippocampal NLRP3 inflammasome in social isolation-induced cognitive impairment in male mice.
NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology.
Small dose of L-dopa/Benserazide hydrochloride improved sepsis-induced neuroinflammation and long-term cognitive dysfunction in sepsis mice.
Huperzine A, reduces brain iron overload and alleviates cognitive deficit in mice exposed to chronic intermittent hypoxia.
Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer's Disease Pathogenesis in Cell and Animal Models.
Fingolimod (FTY720) improves postoperative cognitive dysfunction in mice subjected to D-galactose-induced aging.
Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2.
Cancer cell's neuroendocrine feature can be acquired through cell-cell fusion during cancer-neural stem cell interaction.
Cryopreservation of a Human Brain and Its Experimental Correlate in Rats.
Corticosterone Induced the Increase of proBDNF in Primary Hippocampal Neurons Via Endoplasmic Reticulum Stress.
Subcutaneous administration of β-hydroxybutyrate improves learning and memory of sepsis surviving mice.
Xiaoyao Pills Prevent Lipopolysaccharide-Induced Depression by Inhibiting Inflammation and Protecting Nerves.
MicroRNA-99a is a Potential Target for Regulating Hypothalamic Synaptic Plasticity in the Peri/Postmenopausal Depression Model.
Genomic deletion of TLR2 induces aggravated white matter damage and deteriorated neurobehavioral functions in mouse models of Alzheimer's disease.
Neuroprotective effects of a Smoothened receptor agonist against postoperative cognitive dysfunction by promoting autophagy in the dentate gyrus of aged rats.
Cinnamic acid rescues behavioral deficits in a mouse model of traumatic brain injury by targeting miR-455-3p/HDAC2.
SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis.
Absence of BBSome function leads to astrocyte reactivity in the brain.
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE.
Chronic fluoride exposure induces neuronal apoptosis and impairs neurogenesis and synaptic plasticity: Role of GSK-3β/β-catenin pathway.
PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by influencing synaptic function in the primary motor cortex of rats.
A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets.
Cadmium induces actin cytoskeleton alterations and dysfunction in Neuro-2a cells.
Brain-Derived Neurotrophic Factor Precursor in the Hippocampus Regulates Both Depressive and Anxiety-Like Behaviors in Rats.
Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury.
Metformin Inhibits Prostate Cancer Progression by Targeting Tumor-Associated Inflammatory Infiltration.
Mixed Lineage Kinase Domain-like Protein MLKL Breaks Down Myelin following Nerve Injury.
Rodent Neural Progenitor Cells Support Functional Recovery after Cervical Spinal Cord Contusion.
Pin1 mediates Aβ(42)-induced dendritic spine loss.
Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer's disease.
Quantitative proteomics study of host response to virulent and attenuated pseudorabies virus infection in mouse brain.
Xuefu Zhuyu decoction improves neurological dysfunction by increasing synapsin expression after traumatic brain injury.
Pre-existing weakness is critical for the occurrence of postoperative cognitive dysfunction in mice of the same age.
Sepsis-induced selective loss of NMDA receptors modulates hippocampal neuropathology in surviving septic mice.
Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.
Aqua-soluble DDQ reduces the levels of Drp1 and Aβ and inhibits abnormal interactions between Aβ and Drp1 and protects Alzheimer's disease neurons from Aβ- and Drp1-induced mitochondrial and synaptic toxicities.
The effects of fluoride on neuronal function occurs via cytoskeleton damage and decreased signal transmission.
Chronic administration of parecoxib exerts anxiolytic-like and memory enhancing effects and modulates synaptophysin expression in mice.
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
Identification of TMEM230 mutations in familial Parkinson's disease.
Identification of protein network alterations upon retinal ischemia-reperfusion injury by quantitative proteomics using a Rattus norvegicus model.
Effect of treadmill exercise on 5-HT, 5-HT1A receptor and brain derived neurophic factor in rats after permanent middle cerebral artery occlusion.
Wang S, Chen B, Yuan M, Liu S, Fan H, Yang X, Zou Q, Pu Y, Cai Z
Frontiers in aging neuroscience 2024;16:1340117
Frontiers in aging neuroscience 2024;16:1340117
Thy1-ApoE4/C/EBPβ double transgenic mice act as a sporadic model with Alzheimer's disease.
Qian Z, Wang Z, Li B, Meng X, Kuang Z, Li Y, Yang Y, Ye K
Molecular psychiatry 2024 Oct;29(10):3040-3055
Molecular psychiatry 2024 Oct;29(10):3040-3055
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
Wu Z, Zhou Y, Hou X, Liu W, Yin W, Wang L, Cao Y, Jiang Z, Guo Y, Chen Q, Xie W, Wang Z, Shi N, Liu Y, Gao X, Luo L, Dai J, Ren C, Jiang X
Bioactive materials 2024 May;35:242-258
Bioactive materials 2024 May;35:242-258
Effects of autotaxin and lysophosphatidic acid deficiencies on depression-like behaviors in mice exposed to chronic unpredictable mild stress.
Wang C, Li N, Feng Y, Sun S, Rong J, Xie XH, Xu S, Liu Z
Neurobiology of stress 2024 May;30:100632
Neurobiology of stress 2024 May;30:100632
Hallmark Molecular and Pathological Features of POLG Disease are Recapitulated in Cerebral Organoids.
Chen A, Yangzom T, Hong Y, Lundberg BC, Sullivan GJ, Tzoulis C, Bindoff LA, Liang KX
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2307136
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2307136
Purinergic Astrocyte Signaling Driven by TNF-α After Cannabidiol Administration Restores Normal Synaptic Remodeling Following Traumatic Brain Injury.
Ling T, Yin A, Cao Y, Li J, Li H, Zhou Y, Guo X, Li J, Zhang R, Wu H, Li P
Neuroscience 2024 May 3;545:31-46
Neuroscience 2024 May 3;545:31-46
Gut Microbiota Mediate the Neuroprotective Effect of Oolong Tea Polyphenols in Cognitive Impairment Induced by Circadian Rhythm Disorder.
Song Z, Ho CT, Zhang X
Journal of agricultural and food chemistry 2024 May 29;72(21):12184-12197
Journal of agricultural and food chemistry 2024 May 29;72(21):12184-12197
PAX6 promotes neuroendocrine phenotypes of prostate cancer via enhancing MET/STAT5A-mediated chromatin accessibility.
Jing N, Du X, Liang Y, Tao Z, Bao S, Xiao H, Dong B, Gao WQ, Fang YX
Journal of experimental & clinical cancer research : CR 2024 May 15;43(1):144
Journal of experimental & clinical cancer research : CR 2024 May 15;43(1):144
The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics in response to netrin-1.
McCormick LE, Evans EB, Barker NK, Herring LE, Diering GH, Gupton SL
Molecular biology of the cell 2024 May 1;35(5):ar67
Molecular biology of the cell 2024 May 1;35(5):ar67
Bilirubin impairs neuritogenesis and synaptogenesis in NSPCs by downregulating NMDAR-CREB-BDNF signaling.
Zhang Y, Li S, Li L, Huang H, Fu Z, Hua Z
In vitro cellular & developmental biology. Animal 2024 Mar;60(2):161-171
In vitro cellular & developmental biology. Animal 2024 Mar;60(2):161-171
Bavachin ameliorates neuroinflammation and depressive-like behaviors in streptozotocin-induced diabetic mice through the inhibition of PKCδ.
Zhang Z, Sun L, Guo Y, Zhao J, Li J, Pan X, Li Z
Free radical biology & medicine 2024 Mar;213:52-64
Free radical biology & medicine 2024 Mar;213:52-64
Dietary Restriction Improves Perioperative Neurocognitive Disorders by Inhibiting Neuroinflammation and Gut Microbial Dysbiosis.
Ren L, Liang H, Zhu L, Yang X, Zhang H, Sun N, Huang D, Feng J, Wu Y, Xiong L, Ke X, Li M, Zhang A
Neuroscience 2024 Mar 5;540:48-67
Neuroscience 2024 Mar 5;540:48-67
Volatile oil of Angelica sinensis Radix improves cognitive function by inhibiting miR-301a-3p targeting Ppp2ca in cerebral ischemia mice.
Zhao J, Luo J, Deng C, Fan Y, Liu N, Cao J, Chen D, Diao Y
Journal of ethnopharmacology 2024 Mar 25;322:117621
Journal of ethnopharmacology 2024 Mar 25;322:117621
Periplaneta Americana (L.) extract activates the ERK/CREB/BDNF pathway to promote post-stroke neuroregeneration and recovery of neurological functions in rats.
Rao J, Li H, Zhang H, Xiang X, Ding X, Li L, Geng F, Qi H
Journal of ethnopharmacology 2024 Mar 1;321:117400
Journal of ethnopharmacology 2024 Mar 1;321:117400
Brassisterol A, a new ergosterol from co-cultivation of fungi attenuates neuroinflammation via targeting NLRP3/caspase-1/GSDMD pathway.
Tong Z, Kong L, Zhang Y, Hu T, Dai R, Wang Y, Ji J, Huang Z, Hu L
Bioorganic chemistry 2024 Jan;142:106955
Bioorganic chemistry 2024 Jan;142:106955
YTHDF3 modulates the Cbln1 level by recruiting BTG2 and is implicated in the impaired cognition of prenatal hypoxia offspring.
Lu L, Shi Y, Wei B, Li W, Yu X, Zhao Y, Yu D, Sun M
iScience 2024 Jan 19;27(1):108703
iScience 2024 Jan 19;27(1):108703
GR/Ahi1 regulates WDR68-DYRK1A binding and mediates cognitive impairment in prenatally stressed offspring.
Wei B, Shi H, Yu X, Shi Y, Zeng H, Zhao Y, Zhao Z, Song Y, Sun M, Wang B
Cellular and molecular life sciences : CMLS 2024 Jan 10;81(1):20
Cellular and molecular life sciences : CMLS 2024 Jan 10;81(1):20
The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics.
McCormick LE, Evans EB, Barker NK, Herring LE, Diering GH, Gupton SL
bioRxiv : the preprint server for biology 2024 Jan 1;
bioRxiv : the preprint server for biology 2024 Jan 1;
Prednisolone improves hippocampal regeneration after trimethyltin-induced neurodegeneration in association with prevention of T lymphocyte infiltration.
Sakurai M, Takenaka M, Mitsui Y, Sakai Y, Morimoto M
Neuropathology : official journal of the Japanese Society of Neuropathology 2024 Feb;44(1):21-30
Neuropathology : official journal of the Japanese Society of Neuropathology 2024 Feb;44(1):21-30
Safranal acts as a neurorestorative agent in rats with cerebral ischemic stroke via upregulating SIRT1.
He F, Chen C, Wang Y, Wang S, Lyu S, Jiao J, Huang G, Yang J
Experimental and therapeutic medicine 2024 Feb;27(2):71
Experimental and therapeutic medicine 2024 Feb;27(2):71
Microglial Ffar4 deficiency promotes cognitive impairment in the context of metabolic syndrome.
Wang W, Li J, Cui S, Li J, Ye X, Wang Z, Zhang T, Jiang X, Kong Y, Chen X, Chen YQ, Zhu S
Science advances 2024 Feb 2;10(5):eadj7813
Science advances 2024 Feb 2;10(5):eadj7813
Psoralen protects neurons and alleviates neuroinflammation by regulating microglial M1/M2 polarization via inhibition of the Fyn-PKCδ pathway.
Guo Y, Xu S, Pan X, Xin W, Cao W, Ma W, Li L, Shen Q, Li Z
International immunopharmacology 2024 Aug 20;137:112493
International immunopharmacology 2024 Aug 20;137:112493
GDF1 ameliorates cognitive impairment induced by hearing loss.
Pan L, Li C, Meng L, Zhang G, Zou L, Tian Y, Chen S, Sun Y, Su D, Zhang X, Xiong M, Xiao T, Xia D, Hong Z, Zhang Z
Nature aging 2024 Apr;4(4):568-583
Nature aging 2024 Apr;4(4):568-583
Exercise attenuates the perioperative neurocognitive disorder induced by hyperhomocysteinemia in mice.
Zhang Q, Cong P, Tian L, Wu T, Huang X, Zhang Y, Wu H, Liang H, Xiong L
Brain research bulletin 2024 Apr;209:110913
Brain research bulletin 2024 Apr;209:110913
Butyrate reduction and HDAC4 increase underlie maternal high fructose-induced metabolic dysfunction in hippocampal astrocytes in female rats.
Wu KLH, Liu WC, Wu CW, Fu MH, Huang HM, Tain YL, Liang CK, Hung CY, Chen IC, Hung PL, Lin YJ, Hirase H
The Journal of nutritional biochemistry 2024 Apr;126:109571
The Journal of nutritional biochemistry 2024 Apr;126:109571
Huanglian Jiedu decoction alleviates neurobehavioral damage in mice with chronic alcohol exposure through the RAS-RAF-MEK-ERK pathway.
Chen Y, Jiang L, Li M, Shen Y, Liu S, Yang D
Heliyon 2024 Apr 30;10(8):e29556
Heliyon 2024 Apr 30;10(8):e29556
Agomirs upregulating carboxypeptidase E expression rescue hippocampal neurogenesis and memory deficits in Alzheimer's disease.
Jiang D, Liu H, Li T, Zhao S, Yang K, Yao F, Zhou B, Feng H, Wang S, Shen J, Tang J, Zhang YX, Wang Y, Guo C, Tang TS
Translational neurodegeneration 2024 Apr 26;13(1):24
Translational neurodegeneration 2024 Apr 26;13(1):24
The Involvement of Progranulin for α-Synuclein Reduction through Autolysosome Formation.
Fujimori H, Ohba T, Nakamura S, Shimazawa M, Hara H
Biological & pharmaceutical bulletin 2023;46(8):1032-1040
Biological & pharmaceutical bulletin 2023;46(8):1032-1040
Periventricular Microglia Polarization and Morphological Changes Accompany NLRP3 Inflammasome-Mediated Neuroinflammation after Hypoxic-Ischemic White Matter Damage in Premature Rats.
Yang L, Zhang Y, Yu X, Li D, Liu N, Xue X, Fu J
Journal of immunology research 2023;2023:5149306
Journal of immunology research 2023;2023:5149306
Dietary High-Fat Promotes Cognitive Impairment by Suppressing Mitophagy.
Wen J, Wang Y, Wang C, Yuan M, Chen F, Zou Q, Cai Z, Zhao B
Oxidative medicine and cellular longevity 2023;2023:4822767
Oxidative medicine and cellular longevity 2023;2023:4822767
Huperzine A-Liposomes Efficiently Improve Neural Injury in the Hippocampus of Mice with Chronic Intermittent Hypoxia.
Yang XY, Geng L, Li R, Song JX, Jia CL, An JR, Sun MF, Xu S, Guo YJ, Zhao Y, Ji ES
International journal of nanomedicine 2023;18:843-859
International journal of nanomedicine 2023;18:843-859
A single intranasal dose of human mesenchymal stem cell-derived extracellular vesicles after traumatic brain injury eases neurogenesis decline, synapse loss, and BDNF-ERK-CREB signaling.
Kodali M, Madhu LN, Reger RL, Milutinovic B, Upadhya R, Attaluri S, Shuai B, Shankar G, Shetty AK
Frontiers in molecular neuroscience 2023;16:1185883
Frontiers in molecular neuroscience 2023;16:1185883
Dysfunction of inhibitory interneurons contributes to synaptic plasticity via GABABR-pNR2B signaling in a chronic migraine rat model.
Zeng X, Niu Y, Qin G, Zhang D, Chen L
Frontiers in molecular neuroscience 2023;16:1142072
Frontiers in molecular neuroscience 2023;16:1142072
Neuroprotective Effects of Leptin on the APP/PS1 Alzheimer's Disease Mouse Model: Role of Microglial and Neuroinflammation.
Ma J, Hou YH, Liao ZY, Ma Z, Zhang XX, Wang JL, Zhu YB, Shan HL, Wang PY, Li CB, Lv YL, Wei YL, Dou JZ
Degenerative neurological and neuromuscular disease 2023;13:69-79
Degenerative neurological and neuromuscular disease 2023;13:69-79
Neuroprotective effect of salidroside on hippocampal neurons in diabetic mice via PI3K/Akt/GSK-3β signaling pathway.
Wang XH, Zuo ZF, Meng L, Yang Q, Lv P, Zhao LP, Wang XB, Wang YF, Huang Y, Fu C, Liu WQ, Liu XZ, Zheng DY
Psychopharmacology 2023 Sep;240(9):1865-1876
Psychopharmacology 2023 Sep;240(9):1865-1876
Chronic Kidney Disease Induces Cognitive Impairment in the Early Stage.
Wang Y, Chen K, Qiao ZX, Bao XR
Current medical science 2023 Oct;43(5):988-997
Current medical science 2023 Oct;43(5):988-997
Clemastine fumarate attenuates tauopathy and meliorates cognition in hTau mice via autophagy enhancement.
Zhu J, Jiang X, Chang Y, Wu Y, Sun S, Wang C, Zheng S, Wang M, Yao Y, Li G, Ma R
International immunopharmacology 2023 Oct;123:110649
International immunopharmacology 2023 Oct;123:110649
Electroacupuncture alleviates PTSD-like behaviors by modulating hippocampal synaptic plasticity via Wnt/β-catenin signaling pathway.
Lv T, Wang M, Zheng HS, Mao JD, Yang F, Yang L, Zhao MG, Liu SB, Zhang K, Liu R, Wu YM
Brain research bulletin 2023 Oct 1;202:110734
Brain research bulletin 2023 Oct 1;202:110734
CNTN1 Aggravates Neuroinflammation and Triggers Cognitive Deficits in Male Mice by Boosting Crosstalk between Microglia and Astrocytes.
Li SJ, Ma MH, Li JM, Lu XY, Lu CB, Zhou SF, Zhang LX, Li MQ, Shao TZ, Bai SP, Yan XX, Li F, Li CQ
Aging and disease 2023 Oct 1;14(5):1853-1869
Aging and disease 2023 Oct 1;14(5):1853-1869
The role of EndophilinA1 in chronic unpredicted mild stress-induced depression model mice.
Liu M, Ling Y, Zhang Y, Liu L, Qiu Y, Liu Y, Yin Y
International immunopharmacology 2023 Nov;124(Pt B):111023
International immunopharmacology 2023 Nov;124(Pt B):111023
ChemR23 activation attenuates cognitive impairment in chronic cerebral hypoperfusion by inhibiting NLRP3 inflammasome-induced neuronal pyroptosis.
Zhang Y, Zhang J, Zhao Y, Zhang Y, Liu L, Xu X, Wang X, Fu J
Cell death & disease 2023 Nov 6;14(11):721
Cell death & disease 2023 Nov 6;14(11):721
The yeast prion protein Sup35 initiates α-synuclein pathology in mouse models of Parkinson's disease.
Meng L, Liu C, Li Y, Chen G, Xiong M, Yu T, Pan L, Zhang X, Zhou L, Guo T, Yuan X, Liu C, Zhang Z, Zhang Z
Science advances 2023 Nov 3;9(44):eadj1092
Science advances 2023 Nov 3;9(44):eadj1092
The yeast protein Ure2p triggers Tau pathology in a mouse model of tauopathy.
Meng L, Liu C, Liu M, Chen J, Liu C, Zhang Z, Chen G, Zhang Z
Cell reports 2023 Nov 28;42(11):113342
Cell reports 2023 Nov 28;42(11):113342
Inhibition of RhoA/ROCK signalling pathway activity improves neural damage and cognitive deficits in the fluorosis model.
Lingli C, Hongmei N, Penghuan J, Hongli Z, Yuye L, Rui W, Fei R, Zhihong Y, Dongfang H, Yaming G
Ecotoxicology and environmental safety 2023 Nov 1;266:115554
Ecotoxicology and environmental safety 2023 Nov 1;266:115554
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway.
Sun X, Huang LY, Pan HX, Li LJ, Wang L, Pei GQ, Wang Y, Zhang Q, Cheng HX, He CQ, Wei Q
Neural regeneration research 2023 May;18(5):1067-1075
Neural regeneration research 2023 May;18(5):1067-1075
Integrin β1/FAK/SRC signal pathway is involved in autism spectrum disorder in Tspan7 knockout rats.
Pang S, Luo Z, Dong W, Gao S, Chen W, Liu N, Zhang X, Gao X, Li J, Gao K, Shi X, Guan F, Zhang L, Zhang L
Life science alliance 2023 Mar;6(3)
Life science alliance 2023 Mar;6(3)
Bilirubin Induces A1-Like Reactivity of Astrocyte.
Li S, Huang H, Zhang Y, Li L, Hua Z
Neurochemical research 2023 Mar;48(3):804-815
Neurochemical research 2023 Mar;48(3):804-815
Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.
Lun J, Li Y, Gao X, Gong Z, Chen X, Zou J, Zhou C, Huang Y, Zhou B, Huang P, Cao H
Journal of neuroinflammation 2023 Mar 30;20(1):87
Journal of neuroinflammation 2023 Mar 30;20(1):87
Prenatal alcohol exposure enhanced alcohol preference and susceptibility to PTSD in a sex-dependent manner through the synaptic HCN1 channel.
Yao H, Wang C, Xia Z
Journal of affective disorders 2023 Mar 1;324:143-152
Journal of affective disorders 2023 Mar 1;324:143-152
Polydatin Alleviates Chronic Stress-Induced Depressive and Anxiety-like Behaviors in a Mouse Model.
Wang J, Men Y, Wang Z
ACS chemical neuroscience 2023 Mar 1;14(5):977-987
ACS chemical neuroscience 2023 Mar 1;14(5):977-987
Magnify is a universal molecular anchoring strategy for expansion microscopy.
Klimas A, Gallagher BR, Wijesekara P, Fekir S, DiBernardo EF, Cheng Z, Stolz DB, Cambi F, Watkins SC, Brody SL, Horani A, Barth AL, Moore CI, Ren X, Zhao Y
Nature biotechnology 2023 Jun;41(6):858-869
Nature biotechnology 2023 Jun;41(6):858-869
Exposure to bisphenol A induces neurotoxicity associated with synaptic and cytoskeletal dysfunction in neuro-2a cells.
Wang S, Ning H, Wang X, Chen L, Hua L, Ren F, Hu D, Li R, Ma Z, Ge Y, Yin Z
Toxicology and industrial health 2023 Jun;39(6):325-335
Toxicology and industrial health 2023 Jun;39(6):325-335
Gut Microbiota Taxon-Dependent Transformation of Microglial M1/M2 Phenotypes Underlying Mechanisms of Spatial Learning and Memory Impairment after Chronic Methamphetamine Exposure.
Wu Y, Dong Z, Jiang X, Qu L, Zhou W, Sun X, Hou J, Xu H, Cheng M
Microbiology spectrum 2023 Jun 15;11(3):e0030223
Microbiology spectrum 2023 Jun 15;11(3):e0030223
Islet amyloid polypeptide triggers α-synuclein pathology in Parkinson's disease.
Meng L, Li Y, Liu C, Zhang G, Chen J, Xiong M, Pan L, Zhang X, Chen G, Xiong J, Liu C, Xu X, Bu L, Zhang Z, Zhang Z
Progress in neurobiology 2023 Jul;226:102462
Progress in neurobiology 2023 Jul;226:102462
SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes.
Chang Y, Wang C, Zhu J, Zheng S, Sun S, Wu Y, Jiang X, Li L, Ma R, Li G
Journal of translational medicine 2023 Jul 22;21(1):494
Journal of translational medicine 2023 Jul 22;21(1):494
FTO-dependent m(6)A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke.
Li B, Xi W, Bai Y, Liu X, Zhang Y, Li L, Bian L, Liu C, Tang Y, Shen L, Yang L, Gu X, Xie J, Zhou Z, Wang Y, Yu X, Wang J, Chao J, Han B, Yao H
Nature communications 2023 Jan 30;14(1):489
Nature communications 2023 Jan 30;14(1):489
Atmospheric particulate matter impairs cognition by modulating synaptic function via the nose-to-brain route.
Liang C, Jiang Y, Zhang T, Ji Y, Zhang Y, Sun Y, Li S, Qi Y, Wang Y, Cai Y, Lai T, Cui L
The Science of the total environment 2023 Jan 20;857(Pt 3):159600
The Science of the total environment 2023 Jan 20;857(Pt 3):159600
Tunicamycin induces depression-like behaviors in male rats, accompanied by initiated chaperon-mediated autophagy and decreased synaptic protein expression in the hippocampus.
Yuan G, Xiao L, Xie Y, Si L, Xu H, Xu W, Wang G
Neuroscience letters 2023 Feb 28;798:137058
Neuroscience letters 2023 Feb 28;798:137058
Infralimbic YTHDF1 is necessary for the beneficial effects of acute mild exercise on auditory fear extinction retention.
Li SJ, Zhang LX, Zou GJ, Ma MH, Zhou SF, Lu XY, Li F, Li CQ
Cerebral cortex (New York, N.Y. : 1991) 2023 Feb 20;33(5):1814-1825
Cerebral cortex (New York, N.Y. : 1991) 2023 Feb 20;33(5):1814-1825
Copper Induces Cognitive Impairment in Mice via Modulation of Cuproptosis and CREB Signaling.
Zhang Y, Zhou Q, Lu L, Su Y, Shi W, Zhang H, Liu R, Pu Y, Yin L
Nutrients 2023 Feb 15;15(4)
Nutrients 2023 Feb 15;15(4)
Aerobic glycolysis is the predominant means of glucose metabolism in neuronal somata, which protects against oxidative damage.
Wei Y, Miao Q, Zhang Q, Mao S, Li M, Xu X, Xia X, Wei K, Fan Y, Zheng X, Fang Y, Mei M, Zhang Q, Ding J, Fan Y, Lu M, Hu G
Nature neuroscience 2023 Dec;26(12):2081-2089
Nature neuroscience 2023 Dec;26(12):2081-2089
Ginsenoside Rb1 protects hippocampal neurons in depressed rats based on mitophagy-regulated astrocytic pyroptosis.
Li Y, Li J, Yang L, Ren F, Dong K, Zhao Z, Duan W, Wei W, Guo R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155083
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155083
Extracellular vesicles from hiPSC-NSCs can prevent peripheral inflammation-induced cognitive dysfunction with inflammasome inhibition and improved neurogenesis in the hippocampus.
Ayyubova G, Kodali M, Upadhya R, Madhu LN, Attaluri S, Somayaji Y, Shuai B, Rao S, Shankar G, Shetty AK
Journal of neuroinflammation 2023 Dec 12;20(1):297
Journal of neuroinflammation 2023 Dec 12;20(1):297
Gypenoside IX restores Akt/GSK-3β pathway and alleviates Alzheimer's disease-like neuropathology and cognitive deficits.
Lei L, Luo Y, Kang D, Yang F, Meng D, Wang JZ, Liu R, Wang X, Li HL
Aging 2023 Dec 12;15(23):14172-14191
Aging 2023 Dec 12;15(23):14172-14191
Homocysteine impedes neurite outgrowth recovery after intracerebral haemorrhage by downregulating pCAMK2A.
Guo G, Yang J, Guo W, Deng H, Yu H, Bai S, Li G, Tang Y, Zhang P, Xu Y, Pan C, Tang Z
Stroke and vascular neurology 2023 Aug;8(4):335-348
Stroke and vascular neurology 2023 Aug;8(4):335-348
Sirt1 Overexpression Inhibits Fibrous Scar Formation and Improves Functional Recovery After Cerebral Ischemic Injury Through the Deacetylation of 14-3-3ζ.
Chen Y, Huang J, Liu J, Zhu H, Li X, Wen J, Tian M, Ren J, Zhou L, Yang Q
Molecular neurobiology 2023 Aug;60(8):4795-4810
Molecular neurobiology 2023 Aug;60(8):4795-4810
CNTN1 in the Nucleus Accumbens is Involved in Methamphetamine-Induced Conditioned Place Preference in Mice.
Zhang L, Zeng Z, Lu X, Li M, Yao J, Zou G, Chen Z, Li Q, Li C, Li F
Neurotoxicity research 2023 Aug;41(4):324-337
Neurotoxicity research 2023 Aug;41(4):324-337
The microglial innate immune receptors TREM-1 and TREM-2 in the anterior cingulate cortex (ACC) drive visceral hypersensitivity and depressive-like behaviors following DSS-induced colitis.
Wu K, Liu YY, Shao S, Song W, Chen XH, Dong YT, Zhang YM
Brain, behavior, and immunity 2023 Aug;112:96-117
Brain, behavior, and immunity 2023 Aug;112:96-117
The effects of acupuncture on depression by regulating BDNF-related balance via lateral habenular nucleus BDNF/TrkB/CREB signaling pathway in rats.
Tong T, Chen Y, Hao C, Shen J, Chen W, Cheng W, Yan S, Li J, Li Y, Gulizhaerkezi T, Zeng J, Meng X
Behavioural brain research 2023 Aug 5;451:114509
Behavioural brain research 2023 Aug 5;451:114509
Aerobic Exercise Facilitates the Nuclear Translocation of SREBP2 by Activating AKT/SEC24D to Contribute Cholesterol Homeostasis for Improving Cognition in APP/PS1 Mice.
Hu Z, Yuan Y, Tong Z, Liao M, Yuan S, Wu W, Tang Y, Wang Y, Tang C, Liu W
International journal of molecular sciences 2023 Aug 16;24(16)
International journal of molecular sciences 2023 Aug 16;24(16)
A terrified-sound stress causes cognitive impairment in female mice by impairing neuronal plasticity.
Gao S, Zhang L, Wang X, Li R, Han L, Xiong X, Jiang Q, Cheng D, Xiao X, Li H, Yang J
Brain research 2023 Aug 1;1812:148419
Brain research 2023 Aug 1;1812:148419
Corticostriatal Projections Relying on GABA Levels Mediate Exercise-Induced Functional Recovery in Cerebral Ischemic Mice.
Xing Y, Zhang A, Li C, Han J, Wang J, Luo L, Chang X, Tian Z, Bai Y
Molecular neurobiology 2023 Apr;60(4):1836-1853
Molecular neurobiology 2023 Apr;60(4):1836-1853
Thymol improves autism-like behaviour in VPA-induced ASD rats through the Pin1/p38 MAPK pathway.
Xiong Y, Chen J, Lv M, Wang F, Zhang H, Tang B, Li Y
International immunopharmacology 2023 Apr;117:109885
International immunopharmacology 2023 Apr;117:109885
miR-6315 silencing protects against spinal cord injury through the Smo and anti-ferroptosis pathway.
Ma Z, Fan Y, Peng Y, Bian L, Zhou J, Wang L, Xia Y, Zheng S, Ji Y, Han Y, Feng C, Ba Y
Bioscience reports 2023 Apr 26;43(4)
Bioscience reports 2023 Apr 26;43(4)
Exercise training remodels inguinal white adipose tissue through adaptations in innervation, vascularization, and the extracellular matrix.
Nigro P, Vamvini M, Yang J, Caputo T, Ho LL, Carbone NP, Papadopoulos D, Conlin R, He J, Hirshman MF, White JD, Robidoux J, Hickner RC, Nielsen S, Pedersen BK, Kellis M, Middelbeek RJW, Goodyear LJ
Cell reports 2023 Apr 25;42(4):112392
Cell reports 2023 Apr 25;42(4):112392
The role of reactive astrocytes in neurotoxicity induced by ultrafine particulate matter.
Li B, Chang X, Liang X, Liu T, Shen Y, Zhang Q, Yang X, Lyu Y, Liu L, Guo J, Wu M, Gao Y, Yan X, Wang T, Zhang W, Qiu Y, Zheng J
The Science of the total environment 2023 Apr 1;867:161416
The Science of the total environment 2023 Apr 1;867:161416
Peripheral Transplantation of Mesenchymal Stem Cells at Sepsis Convalescence Improves Cognitive Function of Sepsis Surviving Mice.
Tan L, Cheng Y, Wang H, Tong J, Qin X
Oxidative medicine and cellular longevity 2022;2022:6897765
Oxidative medicine and cellular longevity 2022;2022:6897765
Treatment Combining Focused Ultrasound with Gastrodin Alleviates Memory Deficit and Neuropathology in an Alzheimer's Disease-Like Experimental Mouse Model.
Luo K, Wang Y, Chen WS, Feng X, Liao Y, Chen S, Liu Y, Liao C, Chen M, Ao L
Neural plasticity 2022;2022:5241449
Neural plasticity 2022;2022:5241449
Protective effect of microorganism biotransformation-produced resveratrol on the high fat diet-induced hyperlipidemia, hepatic steatosis and synaptic impairment in hamsters.
Su CH, Wang HL, Tsai ML, Lin YC, Liao JM, Yen CC, Ting HC, Yu CH
International journal of medical sciences 2022;19(10):1586-1595
International journal of medical sciences 2022;19(10):1586-1595
Confinement induces oxidative damage and synaptic dysfunction in mice.
Li N, Wang H, Xin S, Min R, Zhang Y, Deng Y
Frontiers in physiology 2022;13:999574
Frontiers in physiology 2022;13:999574
Hippocampal Iron Accumulation Impairs Synapses and Memory via Suppressing Furin Expression and Downregulating BDNF Maturation.
Zhang Y, Bai X, Zhang Y, Yao S, Cui Y, You LH, Yu P, Chang YZ, Gao G
Molecular neurobiology 2022 Sep;59(9):5574-5590
Molecular neurobiology 2022 Sep;59(9):5574-5590
RNF220 is an E3 ubiquitin ligase for AMPA receptors to regulate synaptic transmission.
Ma P, Wan LP, Li Y, He CH, Song NN, Zhao S, Wang H, Ding YQ, Mao B, Sheng N
Science advances 2022 Sep 30;8(39):eabq4736
Science advances 2022 Sep 30;8(39):eabq4736
Combined cell grafting and VPA administration facilitates neural repair through axonal regeneration and synaptogenesis in traumatic brain injury.
Liu S, Tian H, Niu Y, Yu C, Xie L, Jin Z, Niu W, Ren J, Fu L, Yao Z
Acta biochimica et biophysica Sinica 2022 Sep 25;54(9):1289-1300
Acta biochimica et biophysica Sinica 2022 Sep 25;54(9):1289-1300
Profile of chimeric RNAs and TMPRSS2-ERG e2e4 isoform in neuroendocrine prostate cancer.
Wang Q, Chen J, Singh S, Xie Z, Qin F, Shi X, Cornelison R, Li H, Huang H
Cell & bioscience 2022 Sep 10;12(1):153
Cell & bioscience 2022 Sep 10;12(1):153
Evaluation of Neurotoxicity in BALB/c Mice following Chronic Exposure to Polystyrene Microplastics.
Jin H, Yang C, Jiang C, Li L, Pan M, Li D, Han X, Ding J
Environmental health perspectives 2022 Oct;130(10):107002
Environmental health perspectives 2022 Oct;130(10):107002
Chrysin alleviates lipopolysaccharide-induced neuron damage and behavioral deficits in mice through inhibition of Fyn.
Wang Q, Yang Z, Wu X, Zhang X, Geng F, Wang Q, Geng Z, Yu C, Li Z
International immunopharmacology 2022 Oct;111:109118
International immunopharmacology 2022 Oct;111:109118
Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice.
Li S, Fang Y, Zhang Y, Song M, Zhang X, Ding X, Yao H, Chen M, Sun Y, Ding J, Wang Q, Lu M, Wu G, Hu G
Cell reports 2022 Oct 25;41(4):111532
Cell reports 2022 Oct 25;41(4):111532
Dietary Salt Disrupts Tricarboxylic Acid Cycle and Induces Tau Hyperphosphorylation and Synapse Dysfunction during Aging.
Yuan M, Wang Y, Wen J, Jing F, Zou Q, Pu Y, Pan T, Cai Z
Aging and disease 2022 Oct 1;13(5):1532-1545
Aging and disease 2022 Oct 1;13(5):1532-1545
Fast resupply of synaptic vesicles requires synaptotagmin-3.
Weingarten DJ, Shrestha A, Juda-Nelson K, Kissiwaa SA, Spruston E, Jackman SL
Nature 2022 Nov;611(7935):320-325
Nature 2022 Nov;611(7935):320-325
Differential Expression of Secretogranins II and III in Canine Adrenal Chromaffin Cells and Pheochromocytomas.
Gomi H, Nagumo T, Asano K, Konosu M, Yasui T, Torii S, Hosaka M
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2022 May;70(5):335-356
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2022 May;70(5):335-356
m6A and YTHDF proteins contribute to the localization of select neuronal mRNAs.
Flamand MN, Meyer KD
Nucleic acids research 2022 May 6;50(8):4464-4483
Nucleic acids research 2022 May 6;50(8):4464-4483
Exercise-induced neuroprotection against cerebral ischemia/reperfusion injury is mediated via alleviating inflammasome-induced pyroptosis.
Liu MX, Luo L, Fu JH, He JY, Chen MY, He ZJ, Jia J
Experimental neurology 2022 Mar;349:113952
Experimental neurology 2022 Mar;349:113952
Progranulin improves neural development via the PI3K/Akt/GSK-3β pathway in the cerebellum of a VPA-induced rat model of ASD.
Wang L, Chen J, Hu Y, Liao A, Zheng W, Wang X, Lan J, Shen J, Wang S, Yang F, Wang Y, Li Y, Chen D
Translational psychiatry 2022 Mar 22;12(1):114
Translational psychiatry 2022 Mar 22;12(1):114
Heatstroke-induced late-onset neurological deficits in mice caused by white matter demyelination, Purkinje cell degeneration, and synaptic impairment in the cerebellum.
Miyamoto K, Nakamura M, Ohtaki H, Suzuki K, Yamaga H, Yanagisawa K, Maeda A, Yagi M, Hayashi M, Honda K, Dohi K
Scientific reports 2022 Jun 22;12(1):10598
Scientific reports 2022 Jun 22;12(1):10598
Proteomic analysis of the effects of caffeine in a neonatal rat model of hypoxic-ischemic white matter damage.
Yang L, Yu X, Zhang Y, Liu N, Li D, Xue X, Fu J
CNS neuroscience & therapeutics 2022 Jul;28(7):1019-1032
CNS neuroscience & therapeutics 2022 Jul;28(7):1019-1032
Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor.
Chen B, Qin G, Xiao J, Deng X, Lin A, Liu H
Journal of neuroinflammation 2022 Jul 13;19(1):181
Journal of neuroinflammation 2022 Jul 13;19(1):181
Gestational exposure to fluoride impairs cognition in C57 BL/6 J male offspring mice via the p-Creb1-BDNF-TrkB signaling pathway.
Li W, Lu L, Zhu D, Liu J, Shi Y, Zeng H, Yu X, Guo J, Wei B, Cai Y, Sun M
Ecotoxicology and environmental safety 2022 Jul 1;239:113682
Ecotoxicology and environmental safety 2022 Jul 1;239:113682
DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors.
Chen P, Liu Z, Zhang Q, Lin D, Song L, Liu J, Jiao HF, Lai X, Zou S, Wang S, Zhou T, Li BM, Zhu L, Pan BX, Fei E
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Jan 26;42(4):532-551
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Jan 26;42(4):532-551
The circRNA circ-Nbea participates in regulating diabetic encephalopathy.
Liu J, Deng Z, Yu Z, Zhou W, Yuan Q
Brain research 2022 Jan 1;1774:147702
Brain research 2022 Jan 1;1774:147702
Liraglutide Alleviates Cognitive Deficit in db/db Mice: Involvement in Oxidative Stress, Iron Overload, and Ferroptosis.
An JR, Su JN, Sun GY, Wang QF, Fan YD, Jiang N, Yang YF, Shi Y
Neurochemical research 2022 Feb;47(2):279-294
Neurochemical research 2022 Feb;47(2):279-294
Polygonatum sibiricum ameliorated cognitive impairment of naturally aging rats through BDNF-TrkB signaling pathway.
Zhang X, Ni L, Hu S, Yue B, Chen X, Yuan D, Wang T, Zhou Z
Journal of food biochemistry 2022 Dec;46(12):e14510
Journal of food biochemistry 2022 Dec;46(12):e14510
Effects of neuron autophagy induced by arsenic and fluoride on spatial learning and memory in offspring rats.
Zhao Q, Pan W, Li J, Yu S, Liu Y, Zhang X, Qu R, Zhang Q, Li B, Yan X, Ren X, Qiu Y
Chemosphere 2022 Dec;308(Pt 2):136341
Chemosphere 2022 Dec;308(Pt 2):136341
Heat shock protein Hspa13 regulates endoplasmic reticulum and cytosolic proteostasis through modulation of protein translocation.
Espinoza MF, Nguyen KK, Sycks MM, Lyu Z, Quanrud GM, Montoya MR, Genereux JC
The Journal of biological chemistry 2022 Dec;298(12):102597
The Journal of biological chemistry 2022 Dec;298(12):102597
Inhibition of BRD4 decreases fibrous scarring after ischemic stroke in rats by inhibiting the phosphorylation of Smad2/3.
Li X, Zhu H, Wen J, Huang J, Chen Y, Tian M, Ren J, Zhou L, Yang Q
Brain research 2022 Dec 15;1797:148126
Brain research 2022 Dec 15;1797:148126
FOXO3 Regulates Sevoflurane-Induced Neural Stem Cell Differentiation in Fetal Rats.
Li X, Jiang X, Gao Q, Zhao P
Cellular and molecular neurobiology 2022 Aug;42(6):1777-1786
Cellular and molecular neurobiology 2022 Aug;42(6):1777-1786
Acute lead acetate induces neurotoxicity through decreased synaptic plasticity-related protein expression and disordered dendritic formation in nerve cells.
Chen L, Liu Y, Jia P, Zhang H, Yin Z, Hu D, Ning H, Ge Y
Environmental science and pollution research international 2022 Aug;29(39):58927-58935
Environmental science and pollution research international 2022 Aug;29(39):58927-58935
Identification of distinct genomic features reveals frequent somatic AHNAK and PTEN mutations predominantly in primary malignant melanoma presenting in the ureter.
Huang Y, Wei L, Huang Y, Wen S, Liu T, Duan X, Wang Y, Zhang H, Fan B, Hu B
Japanese journal of clinical oncology 2022 Aug 5;52(8):930-943
Japanese journal of clinical oncology 2022 Aug 5;52(8):930-943
Traumatic Brain Injury Accelerates the Onset of Cognitive Dysfunction and Aggravates Alzheimer's-Like Pathology in the Hippocampus by Altering the Phenotype of Microglia in the APP/PS1 Mouse Model.
Wu D, Kumal JPP, Lu X, Li Y, Mao D, Tang X, Nie M, Liu X, Sun L, Liu B, Zhang Y
Frontiers in neurology 2021;12:666430
Frontiers in neurology 2021;12:666430
Nicotinamide Improves Cognitive Function in Mice With Chronic Cerebral Hypoperfusion.
Liu B, Zhao G, Jin L, Shi J
Frontiers in neurology 2021;12:596641
Frontiers in neurology 2021;12:596641
Postconditioning with Sevoflurane or Propofol Alleviates Lipopolysaccharide-Induced Neuroinflammation but Exerts Dissimilar Effects on the NR2B Subunit and Cognition.
Liu H, Chen B, Guo B, Deng X, Wang B, Dou X
Molecular neurobiology 2021 Sep;58(9):4251-4267
Molecular neurobiology 2021 Sep;58(9):4251-4267
Abnormal spatiotemporal expression pattern of progranulin and neurodevelopment impairment in VPA-induced ASD rat model.
Lan J, Hu Y, Wang X, Zheng W, Liao A, Wang S, Li Y, Wang Y, Yang F, Chen D
Neuropharmacology 2021 Sep 15;196:108689
Neuropharmacology 2021 Sep 15;196:108689
YAP drives fate conversion and chemoresistance of small cell lung cancer.
Wu Q, Guo J, Liu Y, Zheng Q, Li X, Wu C, Fang D, Chen X, Ma L, Xu P, Xu X, Liao C, Wu M, Shen L, Song H
Science advances 2021 Oct;7(40):eabg1850
Science advances 2021 Oct;7(40):eabg1850
Neuroprotective effects of macamide from maca (Lepidium meyenii Walp.) on corticosterone-induced hippocampal impairments through its anti-inflammatory, neurotrophic, and synaptic protection properties.
Yu Z, Li D, Zhai S, Xu H, Liu H, Ao M, Zhao C, Jin W, Yu L
Food & function 2021 Oct 4;12(19):9211-9228
Food & function 2021 Oct 4;12(19):9211-9228
Iptakalim alleviates synaptic damages via targeting mitochondrial ATP-sensitive potassium channel in depression.
Guo W, Tang ZY, Cai ZY, Zhao WE, Yang J, Wang XP, Ji J, Huang XX, Sun XL
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21581
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21581
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.
Li X, Zhang J, Li D, He C, He K, Xue T, Wan L, Zhang C, Liu Q
Neuron 2021 Mar 17;109(6):957-970.e8
Neuron 2021 Mar 17;109(6):957-970.e8
Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease.
Zou L, Zhang X, Xiong M, Meng L, Tian Y, Pan L, Yuan X, Chen G, Wang Z, Bu L, Yao Z, Zhang Z, Ye K, Zhang Z
Neurobiology of disease 2021 Jul;154:105326
Neurobiology of disease 2021 Jul;154:105326
Caloric restriction ameliorates high-fat diet induced cognitive deficits through attenuating neuroinflammation via the TREM2-PI3K/AKT signaling pathway.
Wang R, Zhou Z, Wang D, Zhao Q, Zhang C, Liu C, Zhao H, Yuan C, Yuan D, Wang T
Food & function 2021 Jul 21;12(14):6464-6478
Food & function 2021 Jul 21;12(14):6464-6478
Histone demethylase PHF8 drives neuroendocrine prostate cancer progression by epigenetically upregulating FOXA2.
Liu Q, Pang J, Wang LA, Huang Z, Xu J, Yang X, Xie Q, Huang Y, Tang T, Tong D, Liu G, Wang L, Zhang D, Ma Q, Xiao H, Lan W, Qin J, Jiang J
The Journal of pathology 2021 Jan;253(1):106-118
The Journal of pathology 2021 Jan;253(1):106-118
Hippocampal LASP1 ameliorates chronic stress-mediated behavioral responses in a mouse model of unpredictable chronic mild stress.
Cui YH, Fu A, Wang XQ, Tu BX, Chen KZ, Wang YK, Hu QG, Wang LF, Hu ZL, Pan PH, Li F, Bi FF, Li CQ
Neuropharmacology 2021 Feb 15;184:108410
Neuropharmacology 2021 Feb 15;184:108410
Enriched environment remedies cognitive dysfunctions and synaptic plasticity through NMDAR-Ca(2+)-Activin A circuit in chronic cerebral hypoperfusion rats.
Zhang X, Shi X, Wang J, Xu Z, He J
Aging 2021 Aug 30;13(16):20748-20761
Aging 2021 Aug 30;13(16):20748-20761
Haploinsufficiency of the TDP43 ubiquitin E3 ligase RNF220 leads to ALS-like motor neuron defects in the mouse.
Ma P, Li Y, Wang H, Mao B
Journal of molecular cell biology 2021 Aug 18;13(5):374-382
Journal of molecular cell biology 2021 Aug 18;13(5):374-382
Quantitative proteomic analysis of cortex in the depressive-like behavior of rats induced by the simulated complex space environment.
Min R, Chen Z, Wang Y, Deng Z, Zhang Y, Deng Y
Journal of proteomics 2021 Apr 15;237:104144
Journal of proteomics 2021 Apr 15;237:104144
Curcumin Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behaviors via Restoring Changes in Oxidative Stress and the Activation of Nrf2 Signaling Pathway in Rats.
Liao D, Lv C, Cao L, Yao D, Wu Y, Long M, Liu N, Jiang P
Oxidative medicine and cellular longevity 2020;2020:9268083
Oxidative medicine and cellular longevity 2020;2020:9268083
Xiaoyao Pills Attenuate Inflammation and Nerve Injury Induced by Lipopolysaccharide in Hippocampal Neurons In Vitro.
Fang Y, Shi B, Liu X, Luo J, Rao Z, Liu R, Zeng N
Neural plasticity 2020;2020:8841332
Neural plasticity 2020;2020:8841332
Transplantation of Stem Cells from Human Exfoliated Deciduous Teeth Decreases Cognitive Impairment from Chronic Cerebral Ischemia by Reducing Neuronal Apoptosis in Rats.
Zhu S, Min D, Zeng J, Ju Y, Liu Y, Chen X
Stem cells international 2020;2020:6393075
Stem cells international 2020;2020:6393075
Bisphenol-A exposure induced neurotoxicity and associated with synapse and cytoskeleton in Neuro-2a cells.
Yin Z, Hua L, Chen L, Hu D, Li J, An Z, Tian T, Ning H, Ge Y
Toxicology in vitro : an international journal published in association with BIBRA 2020 Sep;67:104911
Toxicology in vitro : an international journal published in association with BIBRA 2020 Sep;67:104911
Identification and immunohistochemical characterization of G-quadruplexes in mouse brain.
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Biochemical and biophysical research communications 2020 Oct 8;531(1):67-74
Biochemical and biophysical research communications 2020 Oct 8;531(1):67-74
Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice.
Feng T, Mai S, Roscoe JM, Sheng RR, Ullah M, Zhang J, Katz II, Yu H, Xiong W, Hu F
EMBO reports 2020 Oct 5;21(10):e50219
EMBO reports 2020 Oct 5;21(10):e50219
The Neurotrophic Function of Glucagon-Like Peptide-1 Promotes Human Neuroblastoma Differentiation via the PI3K-AKT Axis.
Yang JL, Lin YT, Chen WY, Yang YR, Sun SF, Chen SD
Biology 2020 Oct 22;9(11)
Biology 2020 Oct 22;9(11)
Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells.
Sun Y, He L, Wang T, Hua W, Qin H, Wang J, Wang L, Gu W, Li T, Li N, Liu X, Chen F, Tang L
Molecular neurobiology 2020 Nov;57(11):4628-4641
Molecular neurobiology 2020 Nov;57(11):4628-4641
The critical role of the hippocampal NLRP3 inflammasome in social isolation-induced cognitive impairment in male mice.
Niu L, Luo SS, Xu Y, Wang Z, Luo D, Yang H, Li W, He J, Zhong XL, Liu ZH, Zeng JY, Cao WY, Wan W
Neurobiology of learning and memory 2020 Nov;175:107301
Neurobiology of learning and memory 2020 Nov;175:107301
NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology.
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Cellular & molecular immunology 2020 Mar;17(3):283-299
Cellular & molecular immunology 2020 Mar;17(3):283-299
Small dose of L-dopa/Benserazide hydrochloride improved sepsis-induced neuroinflammation and long-term cognitive dysfunction in sepsis mice.
Li F, Zhang B, Duan S, Qing W, Tan L, Chen S, Wang Y, Li D, Yang J, Tong J, Fang J, Le Y
Brain research 2020 Jun 15;1737:146780
Brain research 2020 Jun 15;1737:146780
Huperzine A, reduces brain iron overload and alleviates cognitive deficit in mice exposed to chronic intermittent hypoxia.
An JR, Zhao YS, Luo LF, Guan P, Tan M, Ji ES
Life sciences 2020 Jun 1;250:117573
Life sciences 2020 Jun 1;250:117573
Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer's Disease Pathogenesis in Cell and Animal Models.
Wei H, Zhang HL, Wang XC, Xie JZ, An DD, Wan L, Wang JZ, Zeng Y, Shu XJ, Westermarck J, Lu YM, Ohlmeyer M, Liu R
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2020 Jul;17(3):1087-1103
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2020 Jul;17(3):1087-1103
Fingolimod (FTY720) improves postoperative cognitive dysfunction in mice subjected to D-galactose-induced aging.
Zhang J, Xiao B, Li CX, Wang Y
Neural regeneration research 2020 Jul;15(7):1308-1315
Neural regeneration research 2020 Jul;15(7):1308-1315
Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2.
Escande-Beillard N, Loh A, Saleem SN, Kanata K, Hashimoto Y, Altunoglu U, Metoska A, Grandjean J, Ng FM, Pomp O, Baburajendran N, Wong J, Hill J, Beillard E, Cozzone P, Zaki M, Kayserili H, Hamada H, Shiratori H, Reversade B
Neuron 2020 Jul 8;107(1):82-94.e6
Neuron 2020 Jul 8;107(1):82-94.e6
Cancer cell's neuroendocrine feature can be acquired through cell-cell fusion during cancer-neural stem cell interaction.
Yin L, Hu P, Shi X, Qian W, Zhau HE, Pandol SJ, Lewis MS, Chung LWK, Wang R
Scientific reports 2020 Jan 27;10(1):1216
Scientific reports 2020 Jan 27;10(1):1216
Cryopreservation of a Human Brain and Its Experimental Correlate in Rats.
Canatelli-Mallat M, Lascaray F, Entraigues-Abramson M, Portiansky EL, Blamaceda N, Morel GR, Goya RG
Rejuvenation research 2020 Dec;23(6):516-525
Rejuvenation research 2020 Dec;23(6):516-525
Corticosterone Induced the Increase of proBDNF in Primary Hippocampal Neurons Via Endoplasmic Reticulum Stress.
Liu Y, Zou GJ, Tu BX, Hu ZL, Luo C, Cui YH, Xu Y, Li F, Dai RP, Bi FF, Li CQ
Neurotoxicity research 2020 Aug;38(2):370-384
Neurotoxicity research 2020 Aug;38(2):370-384
Subcutaneous administration of β-hydroxybutyrate improves learning and memory of sepsis surviving mice.
Wang X, Song Y, Chen J, Zhang S, Le Y, Xie Z, Ouyang W, Tong J
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2020 Apr;17(2):616-626
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2020 Apr;17(2):616-626
Xiaoyao Pills Prevent Lipopolysaccharide-Induced Depression by Inhibiting Inflammation and Protecting Nerves.
Shi B, Luo J, Fang Y, Liu X, Rao Z, Liu R, Zeng N
Frontiers in pharmacology 2019;10:1324
Frontiers in pharmacology 2019;10:1324
MicroRNA-99a is a Potential Target for Regulating Hypothalamic Synaptic Plasticity in the Peri/Postmenopausal Depression Model.
Yang J, Zhang L, Cao LL, Qi J, Li P, Wang XP, Sun XL
Cells 2019 Sep 13;8(9)
Cells 2019 Sep 13;8(9)
Genomic deletion of TLR2 induces aggravated white matter damage and deteriorated neurobehavioral functions in mouse models of Alzheimer's disease.
Zhou C, Sun X, Hu Y, Song J, Dong S, Kong D, Wang Y, Hua X, Han J, Zhou Y, Jin G, Yang X, Shi H, Zhang Z, Hua F
Aging 2019 Sep 11;11(17):7257-7273
Aging 2019 Sep 11;11(17):7257-7273
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Li PJ, Guo YQ, Ding PY, Liu RB, Deng F, Feng XX, Yan WJ
Neurological research 2019 Oct;41(10):867-874
Neurological research 2019 Oct;41(10):867-874
Cinnamic acid rescues behavioral deficits in a mouse model of traumatic brain injury by targeting miR-455-3p/HDAC2.
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Life sciences 2019 Oct 15;235:116819
Life sciences 2019 Oct 15;235:116819
SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis.
Lan Y, Sullivan PM, Hu F
Autophagy 2019 May;15(5):871-885
Autophagy 2019 May;15(5):871-885
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Singh M, Garrison JE, Wang K, Sheffield VC
Molecular brain 2019 May 9;12(1):48
Molecular brain 2019 May 9;12(1):48
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Shah SZA, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, Mangi MH, Wu W, Lai M, Zhang X, Duan Y, Wang L, Zhou X, Yang L
International journal of molecular sciences 2019 Mar 6;20(5)
International journal of molecular sciences 2019 Mar 6;20(5)
SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE.
Raihan O, Brishti A, Li Q, Zhang Q, Li D, Li X, Zhang Q, Xie Z, Li J, Zhang J, Liu Q
Cell reports 2019 Jul 2;28(1):78-90.e6
Cell reports 2019 Jul 2;28(1):78-90.e6
Chronic fluoride exposure induces neuronal apoptosis and impairs neurogenesis and synaptic plasticity: Role of GSK-3β/β-catenin pathway.
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Chemosphere 2019 Jan;214:430-435
Chemosphere 2019 Jan;214:430-435
PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by influencing synaptic function in the primary motor cortex of rats.
Mo J, Wang B, Zhu X, Wu X, Liu Y
Neurobiology of disease 2019 Jan;121:274-285
Neurobiology of disease 2019 Jan;121:274-285
A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets.
Sharon N, Chawla R, Mueller J, Vanderhooft J, Whitehorn LJ, Rosenthal B, Gürtler M, Estanboulieh RR, Shvartsman D, Gifford DK, Trapnell C, Melton D
Cell 2019 Feb 7;176(4):790-804.e13
Cell 2019 Feb 7;176(4):790-804.e13
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Environmental toxicology 2019 Apr;34(4):469-475
Environmental toxicology 2019 Apr;34(4):469-475
Brain-Derived Neurotrophic Factor Precursor in the Hippocampus Regulates Both Depressive and Anxiety-Like Behaviors in Rats.
Zhong F, Liu L, Wei JL, Hu ZL, Li L, Wang S, Xu JM, Zhou XF, Li CQ, Yang ZY, Dai RP
Frontiers in psychiatry 2018;9:776
Frontiers in psychiatry 2018;9:776
Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury.
Wang L, Pei S, Han L, Guo B, Li Y, Duan R, Yao Y, Xue B, Chen X, Jia Y
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Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1535-1559
Metformin Inhibits Prostate Cancer Progression by Targeting Tumor-Associated Inflammatory Infiltration.
Liu Q, Tong D, Liu G, Gao J, Wang LA, Xu J, Yang X, Xie Q, Huang Y, Pang J, Wang L, He Y, Zhang D, Ma Q, Lan W, Jiang J
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Nov 15;24(22):5622-5634
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Nov 15;24(22):5622-5634
Mixed Lineage Kinase Domain-like Protein MLKL Breaks Down Myelin following Nerve Injury.
Ying Z, Pan C, Shao T, Liu L, Li L, Guo D, Zhang S, Yuan T, Cao R, Jiang Z, Chen S, Wang F, Wang X
Molecular cell 2018 Nov 1;72(3):457-468.e5
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Rodent Neural Progenitor Cells Support Functional Recovery after Cervical Spinal Cord Contusion.
Brock JH, Graham L, Staufenberg E, Im S, Tuszynski MH
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Journal of neurotrauma 2018 May 1;35(9):1069-1078
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Stallings NR, O'Neal MA, Hu J, Kavalali ET, Bezprozvanny I, Malter JS
Science signaling 2018 Mar 20;11(522)
Science signaling 2018 Mar 20;11(522)
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Human molecular genetics 2018 Jul 15;27(14):2502-2516
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Biochimica et biophysica acta. Proteins and proteomics 2018 Feb;1866(2):307-315
Biochimica et biophysica acta. Proteins and proteomics 2018 Feb;1866(2):307-315
Xuefu Zhuyu decoction improves neurological dysfunction by increasing synapsin expression after traumatic brain injury.
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Neural regeneration research 2018 Aug;13(8):1417-1424
Neural regeneration research 2018 Aug;13(8):1417-1424
Pre-existing weakness is critical for the occurrence of postoperative cognitive dysfunction in mice of the same age.
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PloS one 2017;12(8):e0182471
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PloS one 2017;12(11):e0188273
PloS one 2017;12(11):e0188273
Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.
Song Z, Shah SZA, Yang W, Dong H, Yang L, Zhou X, Zhao D
Frontiers in molecular neuroscience 2017;10:128
Frontiers in molecular neuroscience 2017;10:128
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Human molecular genetics 2017 Sep 1;26(17):3375-3395
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Chemosphere 2017 Oct;185:589-594
Chemosphere 2017 Oct;185:589-594
Chronic administration of parecoxib exerts anxiolytic-like and memory enhancing effects and modulates synaptophysin expression in mice.
Wang B, Jin X, Kuang X, Tian S
BMC anesthesiology 2017 Nov 13;17(1):152
BMC anesthesiology 2017 Nov 13;17(1):152
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
Shah SZA, Zhao D, Taglialatela G, Khan SH, Hussain T, Dong H, Lai M, Zhou X, Yang L
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Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
Identification of TMEM230 mutations in familial Parkinson's disease.
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Nature genetics 2016 Jul;48(7):733-9
Nature genetics 2016 Jul;48(7):733-9
Identification of protein network alterations upon retinal ischemia-reperfusion injury by quantitative proteomics using a Rattus norvegicus model.
Tian H, Wang L, Cai R, Zheng L, Guo L
PloS one 2014;9(12):e116453
PloS one 2014;9(12):e116453
Effect of treadmill exercise on 5-HT, 5-HT1A receptor and brain derived neurophic factor in rats after permanent middle cerebral artery occlusion.
Lan X, Zhang M, Yang W, Zheng Z, Wu Y, Zeng Q, Liu S, Liu K, Li G
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2014 May;35(5):761-6
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2014 May;35(5):761-6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 17785-1-AP(SYP antibody) at dilution of 1:1500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Synaptophysin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Synaptophysin. This antibody recognizes human,mouse,rat antigen. The Synaptophysin antibody has been validated for the following applications: ELISA, WB, IHC analysis.
