Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 24021-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- CXorf56 antibody
- Antibody type
- Polyclonal
- Description
- CXorf56 antibody (Cat. #24021-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cholesterol-binding motifs in STING that control endoplasmic reticulum retention mediate anti-tumoral activity of cholesterol-lowering compounds.
Inhibition of CXorf56 promotes PARP inhibitor-induced cytotoxicity in triple-negative breast cancer.
The Papain-Like Protease of Porcine Reproductive and Respiratory Syndrome Virus Impedes STING Translocation from the Endoplasmic Reticulum to the Golgi Apparatus by Deubiquitinating STIM1.
A STING antagonist modulating the interaction with STIM1 blocks ER-to-Golgi trafficking and inhibits lupus pathology.
Zhang BC, Laursen MF, Hu L, Hazrati H, Narita R, Jensen LS, Hansen AS, Huang J, Zhang Y, Ding X, Muyesier M, Nilsson E, Banasik A, Zeiler C, Mogensen TH, Etzerodt A, Agger R, Johannsen M, Kofod-Olsen E, Paludan SR, Jakobsen MR
Nature communications 2024 Mar 29;15(1):2760
Nature communications 2024 Mar 29;15(1):2760
Inhibition of CXorf56 promotes PARP inhibitor-induced cytotoxicity in triple-negative breast cancer.
Zhu Y, Liu Z, Gui L, Yun W, Mao C, Deng R, Yao Y, Yu Q, Feng J, Ma H, Bao W
NPJ breast cancer 2023 May 8;9(1):34
NPJ breast cancer 2023 May 8;9(1):34
The Papain-Like Protease of Porcine Reproductive and Respiratory Syndrome Virus Impedes STING Translocation from the Endoplasmic Reticulum to the Golgi Apparatus by Deubiquitinating STIM1.
Diao F, Bai J, Jiang C, Sun Y, Gao Y, Nauwynck H, Jiang P, Liu X
Journal of virology 2023 Apr 27;97(4):e0018823
Journal of virology 2023 Apr 27;97(4):e0018823
A STING antagonist modulating the interaction with STIM1 blocks ER-to-Golgi trafficking and inhibits lupus pathology.
Prabakaran T, Troldborg A, Kumpunya S, Alee I, Marinković E, Windross SJ, Nandakumar R, Narita R, Zhang BC, Carstensen M, Vejvisithsakul P, Marqvorsen MHS, Iversen MB, Holm CK, Østergaard LJ, Pedersen FS, Pisitkun T, Behrendt R, Pisitkun P, Paludan SR
EBioMedicine 2021 Apr;66:103314
EBioMedicine 2021 Apr;66:103314
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The CXorf56 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human CXorf56. This antibody recognizes human, mouse antigen. The CXorf56 antibody has been validated for the following applications: ELISA, WB analysis.