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- Antibody Data
- Antigen structure
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- Product number
- abx032396 - Provider product page
- Provider
- Abbexa
- Product name
- Proteasomal ATPase-Associated Factor 1 (PAAF1) Antibody
- Antibody type
- Polyclonal
- Description
- PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 80 µl
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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