Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Blocking/Neutralizing [1]
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Validation data
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- Product number
- MAB31071 - Provider product page
- Provider
- R&D Systems
- Product name
- Human Relaxin-3 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Recognizes the pro and mature forms of human Relaxin-3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with the pro forms of recombinant human (rh) Relaxin-1 or rhRelaxin-2 is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
Q8WXF3
- Isotype
- IgG
- Antibody clone number
- 332105
- Vial size
- 500 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- cAMP production Induced by Relaxin-3 and Neutralization by Human Relaxin-3 Antibody. Recombinant Human Relaxin-3 (Catalog # 3107-RN) induces cAMP production in the THP-1 human acute monocytic leukemia cell line in a dose-dependent manner (orange line), as measured by cAMP Parameter Assay Kit (Catalog # KGE002B). cAMP production elicited by Recombinant Human Relaxin-3 (25 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human Relaxin-3 Monoclonal Antibody (Catalog # MAB31071). The ND50 is typically 1-5 µg/mL.