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- Antigen structure
- References [15]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 14253-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14253-1-AP, RRID:AB_2288205
- Product name
- UBL4A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated UBL4A antibody (Cat. #14253-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Supercharging-enhanced nDIA-MS enables global profiling of drug-induced proteome solubility shifts.
The tumor promoter 12-O-tetradecanoylphorbol-13-acetate suppresses cell proliferation in metastatic melanoma through TC-PTP/PTPN2 and SH-PTP2/PTPN11.
SEC62-dependent ER-phagy contributes to apelin-13/APJ-induced monocyte-vascular endothelial cell adhesion in atherosclerosis pathogenesis.
Ubiquitin-like 4A alleviates the progression of intracerebral hemorrhage by regulating oxidative stress and mitochondrial damage.
LAMP1 controls CXCL10-CXCR3 axis mediated inflammatory regulation of macrophage polarization during inflammatory stimulation.
GdX inhibits the occurrence and progression of breast cancer by negatively modulating the activity of STAT3.
Chromosomal 3q amplicon encodes essential regulators of secretory vesicles that drive secretory addiction in cancer.
Proteotoxic stresses stimulate dissociation of UBL4A from the tail-anchored protein recognition complex.
Preterm birth alters the feeding-induced activation of Akt signaling in the muscle of neonatal piglets.
C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.
Intermittent Bolus Compared With Continuous Feeding Enhances Insulin and Amino Acid Signaling to Translation Initiation in Skeletal Muscle of Neonatal Pigs.
Mutations in GET4 disrupt the transmembrane domain recognition complex pathway.
UBL4A Augments Innate Immunity by Promoting the K63-Linked Ubiquitination of TRAF6.
UBL4A inhibits autophagy-mediated proliferation and metastasis of pancreatic ductal adenocarcinoma via targeting LAMP1.
SGTA-Dependent Regulation of Hsc70 Promotes Cytosol Entry of Simian Virus 40 from the Endoplasmic Reticulum.
Xiong Y, Zhang H, Tan L, Wei B, Weinstein JN, Lorenzi PL
Nature communications 2026 Jan 30;17(1)
Nature communications 2026 Jan 30;17(1)
The tumor promoter 12-O-tetradecanoylphorbol-13-acetate suppresses cell proliferation in metastatic melanoma through TC-PTP/PTPN2 and SH-PTP2/PTPN11.
Akamatsu Y, Onishi M, Nagano T, Oka M, Kamada S, Iwasaki T
Journal of biochemistry 2025 Sep 30;178(4):237-250
Journal of biochemistry 2025 Sep 30;178(4):237-250
SEC62-dependent ER-phagy contributes to apelin-13/APJ-induced monocyte-vascular endothelial cell adhesion in atherosclerosis pathogenesis.
Chen Z, Cheng J, Zhou Q, Wu LL, Chen JW, Duan XN, Yan JL, Cao JG, Xia XD, Li LF, Chen LX
Acta pharmacologica Sinica 2025 Jun;46(6):1652-1663
Acta pharmacologica Sinica 2025 Jun;46(6):1652-1663
Ubiquitin-like 4A alleviates the progression of intracerebral hemorrhage by regulating oxidative stress and mitochondrial damage.
Li D, Wang L, Shi S, Deng X, Zeng X, Li Y, Li S, Bai P
Experimental animals 2024 Oct 23;73(4):421-432
Experimental animals 2024 Oct 23;73(4):421-432
LAMP1 controls CXCL10-CXCR3 axis mediated inflammatory regulation of macrophage polarization during inflammatory stimulation.
Ye Y, Li L, Kang H, Wan Z, Zhang M, Gang B, Liu J, Liu G, Gu W
International immunopharmacology 2024 May 10;132:111929
International immunopharmacology 2024 May 10;132:111929
GdX inhibits the occurrence and progression of breast cancer by negatively modulating the activity of STAT3.
Chen Z, Xu L, Lin S, Huang H, Long Q, Liu J
Cancer biology & therapy 2024 Dec 31;25(1):2420383
Cancer biology & therapy 2024 Dec 31;25(1):2420383
Chromosomal 3q amplicon encodes essential regulators of secretory vesicles that drive secretory addiction in cancer.
Tan X, Wang S, Xiao GY, Wu C, Liu X, Zhou B, Jiang Y, Duose DY, Xi Y, Wang J, Gupta K, Pataer A, Roth JA, Kim MP, Chen F, Creighton CJ, Russell WK, Kurie JM
The Journal of clinical investigation 2024 Apr 25;134(12)
The Journal of clinical investigation 2024 Apr 25;134(12)
Proteotoxic stresses stimulate dissociation of UBL4A from the tail-anchored protein recognition complex.
Hagiwara T, Minami R, Ushio C, Yokota N, Kawahara H
The Biochemical journal 2023 Oct 11;480(19):1583-1598
The Biochemical journal 2023 Oct 11;480(19):1583-1598
Preterm birth alters the feeding-induced activation of Akt signaling in the muscle of neonatal piglets.
Suryawan A, Rudar M, Naberhuis JK, Fiorotto ML, Davis TA
Pediatric research 2023 Jun;93(7):1891-1898
Pediatric research 2023 Jun;93(7):1891-1898
C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.
Jülg J, Edbauer D, Behrends C
EMBO reports 2023 Aug 3;24(8):e55895
EMBO reports 2023 Aug 3;24(8):e55895
Intermittent Bolus Compared With Continuous Feeding Enhances Insulin and Amino Acid Signaling to Translation Initiation in Skeletal Muscle of Neonatal Pigs.
Suryawan A, El-Kadi SW, Nguyen HV, Fiorotto ML, Davis TA
The Journal of nutrition 2021 Sep 4;151(9):2636-2645
The Journal of nutrition 2021 Sep 4;151(9):2636-2645
Mutations in GET4 disrupt the transmembrane domain recognition complex pathway.
Tambe MA, Ng BG, Shimada S, Wolfe LA, Adams DR, Undiagnosed Diseases Network, Gahl WA, Bamshad MJ, Nickerson DA, Malicdan MCV, Freeze HH
Journal of inherited metabolic disease 2020 Sep;43(5):1037-1045
Journal of inherited metabolic disease 2020 Sep;43(5):1037-1045
UBL4A Augments Innate Immunity by Promoting the K63-Linked Ubiquitination of TRAF6.
Peng SJ, Yao RR, Yu SS, Chen HY, Pang X, Zhang Y, Zhang J
Journal of immunology (Baltimore, Md. : 1950) 2019 Oct 1;203(7):1943-1951
Journal of immunology (Baltimore, Md. : 1950) 2019 Oct 1;203(7):1943-1951
UBL4A inhibits autophagy-mediated proliferation and metastasis of pancreatic ductal adenocarcinoma via targeting LAMP1.
Chen H, Li L, Hu J, Zhao Z, Ji L, Cheng C, Zhang G, Zhang T, Li Y, Chen H, Pan S, Sun B
Journal of experimental & clinical cancer research : CR 2019 Jul 9;38(1):297
Journal of experimental & clinical cancer research : CR 2019 Jul 9;38(1):297
SGTA-Dependent Regulation of Hsc70 Promotes Cytosol Entry of Simian Virus 40 from the Endoplasmic Reticulum.
Dupzyk A, Williams JM, Bagchi P, Inoue T, Tsai B
Journal of virology 2017 Jun 15;91(12)
Journal of virology 2017 Jun 15;91(12)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 14253-1-AP(UBL4A antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using UBL4A antibody 14253-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
