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- References [15]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 24717-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- YEATS2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated YEATS2 antibody (Cat. #24717-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references YEATS2 promotes DNA repair and induces anoikis resistance by enhancing chromatin accessibility to drive prostate cancer metastasis.
YEATS2 promotes malignant phenotypes of esophageal squamous cell carcinoma via H3K27ac activated-IL6ST.
[High YEATS2 expression promotes epithelial-mesenchymal transition in gastric cancer cells by activating the Wnt/β-catenin signaling pathway].
Dynamic interaction of MYC enhancer RNA with YEATS2 protein regulates MYC gene transcription in pancreatic cancer.
YEATS2 O-GlcNAcylation promotes chromatin association of the ATAC complex and lung cancer tumorigenesis.
SUMOylation targets O-GlcNAcase to chaperone-mediated autophagy.
Interplay of YEATS2 and GCDH regulates histone crotonylation and drives EMT in head and neck cancer.
Repression of YEATS2 induces cellular senescence in hepatocellular carcinoma and inhibits tumor growth.
The ATAC complex represses the transcriptional program of the autophagy-lysosome pathway via its E3 ubiquitin ligase activity.
Overexpression of YEATS2 Remodels the Extracellular Matrix to Promote Hepatocellular Carcinoma Progression via the PI3K/AKT Pathway.
YEATS2 regulates the activation of TAK1/NF-κB pathway and is critical for pancreatic ductal adenocarcinoma cell survival.
Cinobufacini retards progression of pancreatic ductal adenocarcinoma through targeting YEATS2/TAK1/NF-κB axis.
Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma.
YEATS2 is a target of HIF1α and promotes pancreatic cancer cell proliferation and migration.
YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.
Li H, Song Y, Cong Y, Wang C, Chen K, Liu C, Zhou M, Ju Y, Chen J, Chen L, Xing Y
Oncogene 2026 Mar;45(11):971-988
Oncogene 2026 Mar;45(11):971-988
YEATS2 promotes malignant phenotypes of esophageal squamous cell carcinoma via H3K27ac activated-IL6ST.
Zhai Y, Zhang F, Shi X, Zou S, Hu X, Shan C, Zhang L, Zou B, Yang X, Kong P, Cheng X
Frontiers in cell and developmental biology 2025;13:1497290
Frontiers in cell and developmental biology 2025;13:1497290
[High YEATS2 expression promotes epithelial-mesenchymal transition in gastric cancer cells by activating the Wnt/β-catenin signaling pathway].
Jiang X, Huang Q, Xu Y, Wang S, Zhang X, Wang L, Wang Y, Zuo L
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Nov 20;45(11):2416-2426
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Nov 20;45(11):2416-2426
Dynamic interaction of MYC enhancer RNA with YEATS2 protein regulates MYC gene transcription in pancreatic cancer.
Roy J, Kumar A, Chakravarty S, Biswas NK, Goswami S, Mazumder A
EMBO reports 2025 May;26(10):2519-2544
EMBO reports 2025 May;26(10):2519-2544
YEATS2 O-GlcNAcylation promotes chromatin association of the ATAC complex and lung cancer tumorigenesis.
Zhao J, Zhao Z, Zhou W, Zhang J, Chen J, Sun J, Li J
The Journal of biological chemistry 2025 Jul;301(7):110388
The Journal of biological chemistry 2025 Jul;301(7):110388
SUMOylation targets O-GlcNAcase to chaperone-mediated autophagy.
Yan S, Yuan A, Shao G, Zhou W, Xu X, Dong MQ, Liu X, Li J
The Journal of biological chemistry 2025 Jul;301(7):110314
The Journal of biological chemistry 2025 Jul;301(7):110314
Interplay of YEATS2 and GCDH regulates histone crotonylation and drives EMT in head and neck cancer.
Pant D, Kakani P, Joshi R, Sabu A, Agrawal S, Samaiya A, Shukla S
eLife 2025 Aug 14;14
eLife 2025 Aug 14;14
Repression of YEATS2 induces cellular senescence in hepatocellular carcinoma and inhibits tumor growth.
Wu Q, Zheng Q, Yuan L, Gao D, Hu Y, Jiang X, Zhai Q, Liu M, Xu L, Xu H, Ye J, Zhang F
Cell cycle (Georgetown, Tex.) 2024 Feb;23(4):478-494
Cell cycle (Georgetown, Tex.) 2024 Feb;23(4):478-494
The ATAC complex represses the transcriptional program of the autophagy-lysosome pathway via its E3 ubiquitin ligase activity.
Wang X, Wang L, Zhou Z, Jiang C, Bao Z, Wang Y, Zhang Y, Song L, Zhao Y, Li X, Li Q, Shen Y, Yu Y, Mi W
Cell reports 2024 Dec 24;43(12):115033
Cell reports 2024 Dec 24;43(12):115033
Overexpression of YEATS2 Remodels the Extracellular Matrix to Promote Hepatocellular Carcinoma Progression via the PI3K/AKT Pathway.
Liu X, Hu Y, Li C, Chen J, Liu X, Shen Y, Xu Y, Chen W, Xu X
Cancers 2023 Mar 20;15(6)
Cancers 2023 Mar 20;15(6)
YEATS2 regulates the activation of TAK1/NF-κB pathway and is critical for pancreatic ductal adenocarcinoma cell survival.
Sheng H, Zheng F, Lan T, Chen HF, Xu CY, Wang SW, Weng YY, Xu LF, Zhang F
Cell biology and toxicology 2023 Jun;39(3):1-16
Cell biology and toxicology 2023 Jun;39(3):1-16
Cinobufacini retards progression of pancreatic ductal adenocarcinoma through targeting YEATS2/TAK1/NF-κB axis.
Lan T, Chen HF, Zheng F, Huang H, Wu Q, Fan XY, Wang SW, Zhang F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154564
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154564
Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma.
Xi Y, Lin Y, Guo W, Wang X, Zhao H, Miao C, Liu W, Liu Y, Liu T, Luo Y, Fan W, Lin A, Chen Y, Sun Y, Ma Y, Niu X, Zhong C, Tan W, Zhou M, Su J, Wu C, Lin D
Signal transduction and targeted therapy 2022 Feb 25;7(1):53
Signal transduction and targeted therapy 2022 Feb 25;7(1):53
YEATS2 is a target of HIF1α and promotes pancreatic cancer cell proliferation and migration.
Zeng Z, Lei S, He Z, Chen T, Jiang J
Journal of cellular physiology 2021 Mar;236(3):2087-2098
Journal of cellular physiology 2021 Mar;236(3):2087-2098
YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.
Mi W, Guan H, Lyu J, Zhao D, Xi Y, Jiang S, Andrews FH, Wang X, Gagea M, Wen H, Tora L, Dent SYR, Kutateladze TG, Li W, Li H, Shi X
Nature communications 2017 Oct 20;8(1):1088
Nature communications 2017 Oct 20;8(1):1088
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 24717-1-AP( YEATS2 Antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The YEATS2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human YEATS2. This antibody recognizes human antigen. The YEATS2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
