Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 21433-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21433-1-AP, RRID:AB_10755299
- Product name
- SLC5A8 antibody
- Antibody type
- Polyclonal
- Description
- SLC5A8 antibody (Cat. #21433-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Gut-confined fullerene reprograms lactate metabolism to Rescue hypoxia-induced exercise intolerance.
Autophagy mediates the impact of Porphyromonas gingivalis on short-chain fatty acids metabolism in periodontitis-induced gut dysbiosis.
Acetate reprogrammes tumour metabolism and promotes PD-L1 expression and immune evasion by upregulating c-Myc.
Downregulation of OATP2B1 by proinflammatory cytokines leads to 5-ASA hyposensitivity in Ulcerative colitis.
Alleviation of allergic asthma by rosmarinic acid via gut-lung axis.
The reduced SCFA-producing gut microbes are involved in the inflammatory activation in Kawasaki disease.
Microbiota-derived short-chain fatty acids mediate the effects of dengzhan shengmai in ameliorating cerebral ischemia via the gut-brain axis.
Gut-derived butyrate suppresses ocular surface inflammation.
Voglibose Regulates the Secretion of GLP-1 Accompanied by Amelioration of Ileal Inflammatory Damage and Endoplasmic Reticulum Stress in Diabetic KKAy Mice.
Ramulus Mori (Sangzhi) Alkaloids (SZ-A) Ameliorate Glucose Metabolism Accompanied by the Modulation of Gut Microbiota and Ileal Inflammatory Damage in Type 2 Diabetic KKAy Mice.
The probiotic L. casei Zhang slows the progression of acute and chronic kidney disease.
Potential Role of SLC5A8 Expression in the Etiology of Subacute Ruminal Acidosis.
Integrative analysis of DNA methylation and gene expression identified cervical cancer-specific diagnostic biomarkers.
Impaired Na(+)-K(+)-ATPase signaling in renal proximal tubule contributes to hyperuricemia-induced renal tubular injury.
Chen S, Pan Y, Liu M, Liu C, Xu Y, Ma J, Li J, Wang X, Yang L, Wang Y, Li B, Wang Z, Zhang Y, Shen H, Wulan Q, Li J, Wang C, Bai C
Biomaterials 2026 Aug;331:124075
Biomaterials 2026 Aug;331:124075
Autophagy mediates the impact of Porphyromonas gingivalis on short-chain fatty acids metabolism in periodontitis-induced gut dysbiosis.
Sun J, Wang X, Xiao J, Yang Q, Huang X, Yang Z, Liu H, Liu Y, Wang H, Huang Z, Ma L, Cao Z
Scientific reports 2024 Nov 1;14(1):26291
Scientific reports 2024 Nov 1;14(1):26291
Acetate reprogrammes tumour metabolism and promotes PD-L1 expression and immune evasion by upregulating c-Myc.
Wang J, Yang Y, Shao F, Meng Y, Guo D, He J, Lu Z
Nature metabolism 2024 May;6(5):914-932
Nature metabolism 2024 May;6(5):914-932
Downregulation of OATP2B1 by proinflammatory cytokines leads to 5-ASA hyposensitivity in Ulcerative colitis.
Li P, Luo J, Jiang Y, Pan X, Dong M, Chen B, Wang J, Zhou H, Jiang H, Duan Y, Lin N
Chemico-biological interactions 2024 Aug 1;398:111074
Chemico-biological interactions 2024 Aug 1;398:111074
Alleviation of allergic asthma by rosmarinic acid via gut-lung axis.
Guo HH, Han YX, Rong XJ, Shen Z, Shen HR, Kong LF, Guo YD, Li JZ, Xu B, Gao TL, Wang LL, Tie C, Jiang JD
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155470
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155470
The reduced SCFA-producing gut microbes are involved in the inflammatory activation in Kawasaki disease.
Wang F, Qian F, Zhang Q, Zhao J, Cen J, Zhang J, Zhou J, Luo M, Jia C, Rong X, Chu M
Frontiers in immunology 2023;14:1124118
Frontiers in immunology 2023;14:1124118
Microbiota-derived short-chain fatty acids mediate the effects of dengzhan shengmai in ameliorating cerebral ischemia via the gut-brain axis.
Guo HH, Shen HR, Tang MZ, Sheng N, Ding X, Lin Y, Zhang JL, Jiang JD, Gao TL, Wang LL, Han YX
Journal of ethnopharmacology 2023 Apr 24;306:116158
Journal of ethnopharmacology 2023 Apr 24;306:116158
Gut-derived butyrate suppresses ocular surface inflammation.
Schaefer L, Hernandez H, Coats RA, Yu Z, Pflugfelder SC, Britton RA, de Paiva CS
Scientific reports 2022 Mar 16;12(1):4512
Scientific reports 2022 Mar 16;12(1):4512
Voglibose Regulates the Secretion of GLP-1 Accompanied by Amelioration of Ileal Inflammatory Damage and Endoplasmic Reticulum Stress in Diabetic KKAy Mice.
Fu Y, Ji W, Liu Q, Zhang L, Li C, Huan Y, Lei L, Gao X, Chen L, Feng C, Lei L, Zhai J, Li P, Cao H, Liu S, Shen Z
International journal of molecular sciences 2022 Dec 14;23(24)
International journal of molecular sciences 2022 Dec 14;23(24)
Ramulus Mori (Sangzhi) Alkaloids (SZ-A) Ameliorate Glucose Metabolism Accompanied by the Modulation of Gut Microbiota and Ileal Inflammatory Damage in Type 2 Diabetic KKAy Mice.
Liu Q, Liu S, Cao H, Ji W, Li C, Huan Y, Lei L, Fu Y, Gao X, Liu Y, Shen Z
Frontiers in pharmacology 2021;12:642400
Frontiers in pharmacology 2021;12:642400
The probiotic L. casei Zhang slows the progression of acute and chronic kidney disease.
Zhu H, Cao C, Wu Z, Zhang H, Sun Z, Wang M, Xu H, Zhao Z, Wang Y, Pei G, Yang Q, Zhu F, Yang J, Deng X, Hong Y, Li Y, Sun J, Zhu F, Shi M, Qian K, Ye T, Zuo X, Zhao F, Guo J, Xu G, Yao Y, Zeng R
Cell metabolism 2021 Oct 5;33(10):1926-1942.e8
Cell metabolism 2021 Oct 5;33(10):1926-1942.e8
Potential Role of SLC5A8 Expression in the Etiology of Subacute Ruminal Acidosis.
Zhao C, Bobe G, Wang Y, Zhang X, Zhao Z, Zhang S, Sun G, Yuan X, Li X, Liu G
Frontiers in veterinary science 2020;7:394
Frontiers in veterinary science 2020;7:394
Integrative analysis of DNA methylation and gene expression identified cervical cancer-specific diagnostic biomarkers.
Xu W, Xu M, Wang L, Zhou W, Xiang R, Shi Y, Zhang Y, Piao Y
Signal transduction and targeted therapy 2019;4:55
Signal transduction and targeted therapy 2019;4:55
Impaired Na(+)-K(+)-ATPase signaling in renal proximal tubule contributes to hyperuricemia-induced renal tubular injury.
Xiao J, Zhang X, Fu C, Yang Q, Xie Y, Zhang Z, Ye Z
Experimental & molecular medicine 2018 Mar 2;50(3):e452
Experimental & molecular medicine 2018 Mar 2;50(3):e452
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 21433-1-AP(SLC5A8 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunofluorescent analysis of Hela cells, using SLC5A8 antibody 21433-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line