HPA023374

antibody from Atlas Antibodies

Targeting: PCM1 PTC4

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA023374

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA023374, RRID:AB_1855073

Product name

Anti-PCM1

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human PCM1, Gene description: pericentriolar material 1, Alternative Gene Names: PTC4, Validated applications: IHC, ICC, Uniprot ID: Q15154, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.3 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

A Latent Cardiomyocyte Regeneration Potential in Human Heart Disease

Derks W, Rode J, Collin S, Rost F, Heinke P, Hariharan A, Pickel L, Simonova I, Lázár E, Graham E, Jashari R, Andrä M, Jeppsson A, Salehpour M, Alkass K, Druid H, Kyriakopoulos C, Taleb I, Shankar T, Selzman C, Sadek H, Jovinge S, Brusch L, Frisén J, Drakos S, Bergmann O
Circulation 2025;151(3):245-256

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Lineage tracing of nuclei in skeletal myofibers uncovers distinct transcripts and interplay between myonuclear populations

Sun C, Swoboda C, Morales F, Calvo C, Petrany M, Parameswaran S, VonHandorf A, Weirauch M, Lepper C, Millay D
Nature Communications 2024;15(1)

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Global ischemia induces stemness and dedifferentiation in human adult cardiomyocytes after cardiac arrest

Jinton H, Sopasakis V, Sjölin L, Oldfors A, Jeppsson A, Oras J, Wernbom M, Vukusic K
Scientific Reports 2024;14(1)

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Catecholamine treatment induces reversible heart injury and cardiomyocyte gene expression

Bode C, Preissl S, Hein L, Lother A
Intensive Care Medicine Experimental 2024;12(1)

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Transcription factor NFYa controls cardiomyocyte metabolism and proliferation during mouse fetal heart development

Cui M, Bezprozvannaya S, Hao T, Elnwasany A, Szweda L, Liu N, Bassel-Duby R, Olson E
Developmental Cell 2023;58(24):2867-2880.e7

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Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity

Tan C, Chan P, Tan H, Tan S, Lee C, Wang J, Ye S, Werner H, Loh Y, Lee Y, Ackers-Johnson M, Foo R, Jiang J
Journal of Translational Medicine 2023;21(1)

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Opposing gene regulatory programs governing myofiber development and maturation revealed at single nucleus resolution

Dos Santos M, Shah A, Zhang Y, Bezprozvannaya S, Chen K, Xu L, Lin W, McAnally J, Bassel-Duby R, Liu N, Olson E
Nature Communications 2023;14(1)

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Sun C, Swoboda C, Petrany M, Parameswaran S, VonHandorf A, Weirauch M, Lepper C, Millay D
2023

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HRas and Myc synergistically induce cell cycle progression and apoptosis of murine cardiomyocytes.

Boikova A, Bywater MJ, Quaife-Ryan GA, Straube J, Thompson L, Ascanelli C, Littlewood TD, Evan GI, Hudson JE, Wilson CH
Frontiers in cardiovascular medicine 2022;9:948281

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RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development

Gan P, Wang Z, Morales M, Zhang Y, Bassel-Duby R, Liu N, Olson E
Developmental Cell 2022;57(8):959-973.e7

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Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing

Cui M, Wang Z, Chen K, Shah A, Tan W, Duan L, Sanchez-Ortiz E, Li H, Xu L, Liu N, Bassel-Duby R, Olson E
Developmental Cell 2020;53(1):102-116.e8

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Dietary protein restriction throughout intrauterine and postnatal life results in potentially beneficial myocardial tissue remodeling in the adult mouse heart

Hennig M, Ewering L, Pyschny S, Shimoyama S, Olecka M, Ewald D, Magarin M, Uebing A, Thierfelder L, Jux C, Drenckhahn J
Scientific Reports 2019;9(1)

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A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes

So C, Seres K, Steyer A, Mönnich E, Clift D, Pejkovska A, Möbius W, Schuh M
Science 2019;364(6447)

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Yin Yang 1 Suppresses Dilated Cardiomyopathy and Cardiac Fibrosis Through Regulation of Bmp7 and Ctgf

Tan C, Wong J, Chan P, Tan H, Liao D, Chen W, Tan L, Ackers-Johnson M, Wakimoto H, Seidman J, Seidman C, Lunde I, Zhu F, Hu Q, Bian J, Wang J, Foo R, Jiang J
Circulation Research 2019;125(9):834-846

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The Atrioventricular Junction: A Potential Niche Region for Progenitor Cells in the Adult Human Heart.

Vukusic K, Sandstedt M, Jonsson M, Jansson M, Oldfors A, Jeppsson A, Dellgren G, Lindahl A, Sandstedt J
Stem cells and development 2019 Aug 15;28(16):1078-1088

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Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction

Zacchigna S, Martinelli V, Moimas S, Colliva A, Anzini M, Nordio A, Costa A, Rehman M, Vodret S, Pierro C, Colussi G, Zentilin L, Gutierrez M, Dirkx E, Long C, Sinagra G, Klatzmann D, Giacca M
Nature Communications 2018;9(1)

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DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes

Nothjunge S, Nührenberg T, Grüning B, Doppler S, Preissl S, Schwaderer M, Rommel C, Krane M, Hein L, Gilsbach R
Nature Communications 2017;8(1)

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Single cardiomyocyte nuclear transcriptomes reveal a lincRNA-regulated de-differentiation and cell cycle stress-response in vivo

See K, Tan W, Lim E, Tiang Z, Lee L, Li P, Luu T, Ackers-Johnson M, Foo R
Nature Communications 2017;8(1)

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A Method for the Acute and Rapid Degradation of Endogenous Proteins

Clift D, McEwan W, Labzin L, Konieczny V, Mogessie B, James L, Schuh M
Cell 2017;171(7):1692-1706.e18

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5'-Hydroxymethylcytosine Precedes Loss of CpG Methylation in Enhancers and Genes Undergoing Activation in Cardiomyocyte Maturation

Deng D, Kranzhöfer D, Gilsbach R, Grüning B, Backofen R, Nührenberg T, Hein L
PLOS ONE 2016;11(11):e0166575

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BBS mutations modify phenotypic expression of CEP290-related ciliopathies

Zhang Y, Seo S, Bhattarai S, Bugge K, Searby C, Zhang Q, Drack A, Stone E, Sheffield V
Human Molecular Genetics 2014;23(1):40-51

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ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting

Humbert M, Weihbrecht K, Searby C, Li Y, Pope R, Sheffield V, Seo S
Proceedings of the National Academy of Sciences 2012;109(48):19691-19696

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Identification of cardiomyocyte nuclei and assessment of ploidy for the analysis of cell turnover

Bergmann O, Zdunek S, Alkass K, Druid H, Bernard S, Frisén J
Experimental Cell Research 2011;317(2):188-194