Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
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Validation data
Reference
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- Product number
- 19856-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- PCM1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PCM1 antibody (Cat. #19856-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A ciliopathy complex builds distal appendages to initiate ciliogenesis.
Novel loss-of-function mutation in HERC2 is associated with severe developmental delay and paediatric lethality.
Diastolic dysfunction in a pre-clinical model of diabetes is associated with changes in the cardiac non-myocyte cellular composition.
Aurora Kinase A proximity map reveals centriolar satellites as regulators of its ciliary function.
Distinct Roles of TRAPPC8 and TRAPPC12 in Ciliogenesis via Their Interactions With OFD1.
ASK1-Mediated Phosphorylation Blocks HDAC6 Ubiquitination and Degradation to Drive the Disassembly of Photoreceptor Connecting Cilia.
CCDC57 Cooperates with Microtubules and Microcephaly Protein CEP63 and Regulates Centriole Duplication and Mitotic Progression.
Centrosomal and ciliary targeting of CCDC66 requires cooperative action of centriolar satellites, microtubules and molecular motors.
Centriolar satellites are required for efficient ciliogenesis and ciliary content regulation.
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
The X-linked deubiquitinase USP9X is an integral component of centrosome.
The centriolar satellite protein CCDC66 interacts with CEP290 and functions in cilium formation and trafficking.
Kumar D, Rains A, Herranz-Pérez V, Lu Q, Shi X, Swaney DL, Stevenson E, Krogan NJ, Huang B, Westlake C, Garcia-Verdugo JM, Yoder BK, Reiter JF
The Journal of cell biology 2021 Sep 6;220(9)
The Journal of cell biology 2021 Sep 6;220(9)
Novel loss-of-function mutation in HERC2 is associated with severe developmental delay and paediatric lethality.
Elpidorou M, Best S, Poulter JA, Hartill V, Hobson E, Sheridan E, Johnson CA
Journal of medical genetics 2021 May;58(5):334-341
Journal of medical genetics 2021 May;58(5):334-341
Diastolic dysfunction in a pre-clinical model of diabetes is associated with changes in the cardiac non-myocyte cellular composition.
Cohen CD, De Blasio MJ, Lee MKS, Farrugia GE, Prakoso D, Krstevski C, Deo M, Donner DG, Kiriazis H, Flynn MC, Gaynor TL, Murphy AJ, Drummond GR, Pinto AR, Ritchie RH
Cardiovascular diabetology 2021 Jun 1;20(1):116
Cardiovascular diabetology 2021 Jun 1;20(1):116
Aurora Kinase A proximity map reveals centriolar satellites as regulators of its ciliary function.
Arslanhan MD, Rauniyar N, Yates JR 3rd, Firat-Karalar EN
EMBO reports 2021 Aug 4;22(8):e51902
EMBO reports 2021 Aug 4;22(8):e51902
Distinct Roles of TRAPPC8 and TRAPPC12 in Ciliogenesis via Their Interactions With OFD1.
Zhang C, Li C, Siu GKY, Luo X, Yu S
Frontiers in cell and developmental biology 2020;8:148
Frontiers in cell and developmental biology 2020;8:148
ASK1-Mediated Phosphorylation Blocks HDAC6 Ubiquitination and Degradation to Drive the Disassembly of Photoreceptor Connecting Cilia.
Ran J, Liu M, Feng J, Li H, Ma H, Song T, Cao Y, Zhou P, Wu Y, Yang Y, Yang Y, Yu F, Guo H, Zhang L, Xie S, Li D, Gao J, Zhang X, Zhu X, Zhou J
Developmental cell 2020 May 4;53(3):287-299.e5
Developmental cell 2020 May 4;53(3):287-299.e5
CCDC57 Cooperates with Microtubules and Microcephaly Protein CEP63 and Regulates Centriole Duplication and Mitotic Progression.
Gurkaslar HK, Culfa E, Arslanhan MD, Lince-Faria M, Firat-Karalar EN
Cell reports 2020 May 12;31(6):107630
Cell reports 2020 May 12;31(6):107630
Centrosomal and ciliary targeting of CCDC66 requires cooperative action of centriolar satellites, microtubules and molecular motors.
Conkar D, Bayraktar H, Firat-Karalar EN
Scientific reports 2019 Oct 3;9(1):14250
Scientific reports 2019 Oct 3;9(1):14250
Centriolar satellites are required for efficient ciliogenesis and ciliary content regulation.
Odabasi E, Gul S, Kavakli IH, Firat-Karalar EN
EMBO reports 2019 Jun;20(6)
EMBO reports 2019 Jun;20(6)
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Li X, Song N, Liu L, Liu X, Ding X, Song X, Yang S, Shan L, Zhou X, Su D, Wang Y, Zhang Q, Cao C, Ma S, Yu N, Yang F, Wang Y, Yao Z, Shang Y, Shi L
Nature communications 2017 Mar 31;8:14866
Nature communications 2017 Mar 31;8:14866
The X-linked deubiquitinase USP9X is an integral component of centrosome.
Wang Q, Tang Y, Xu Y, Xu S, Jiang Y, Dong Q, Zhou Y, Ge W
The Journal of biological chemistry 2017 Aug 4;292(31):12874-12884
The Journal of biological chemistry 2017 Aug 4;292(31):12874-12884
The centriolar satellite protein CCDC66 interacts with CEP290 and functions in cilium formation and trafficking.
Conkar D, Culfa E, Odabasi E, Rauniyar N, Yates JR 3rd, Firat-Karalar EN
Journal of cell science 2017 Apr 15;130(8):1450-1462
Journal of cell science 2017 Apr 15;130(8):1450-1462
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 19856-1-AP(PCM1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP result of anti-PCM1 (19856-1-AP for IP and Detection) with HeLa cells.
- Sample type
- cell line