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- Antigen structure
- References [6]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
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- Product number
- 55178-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- THOC2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated THOC2 antibody (Cat. #55178-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CUL5 E3 ubiquitin ligase regulates the evasion of bladder cancer cells to CD8+ T cell-mediated killing by inhibiting autophagy.
Deciphering lactate/lactylation networks in AML: integrated scRNA-seq and transcriptomics reveal functions and prognostic model.
Targeting mRNA export complex macromolecules THO subunits (Thoc2 and Thoc5) for somatic cell reprograming.
YTHDC1 cooperates with the THO complex to prevent RNA-damage-induced DNA breaks.
Clinical and functional characterization of recurrent missense variants implicated in THOC6-related intellectual disability.
Murine leukemia virus uses TREX components for efficient nuclear export of unspliced viral transcripts.
Gao X, Yu Y, Sun J, Zhao H, You Y, Shi X, Wang K, Hong S, Xiong X, Huang C, Zhang H, Jiang G
PLoS biology 2026 Feb;24(2):e3003647
PLoS biology 2026 Feb;24(2):e3003647
Deciphering lactate/lactylation networks in AML: integrated scRNA-seq and transcriptomics reveal functions and prognostic model.
Chen X, Feng A, Guo H, Zeng J, Chen M
BMC cancer 2025 Oct 25;25(1):1647
BMC cancer 2025 Oct 25;25(1):1647
Targeting mRNA export complex macromolecules THO subunits (Thoc2 and Thoc5) for somatic cell reprograming.
Rehman A, Wang H, Li C, Fatima I, Noor F, Ding Y, He Z, Dong H, Ni Y, Meng Y, Qasim M, Shi X, Liao M
International journal of biological macromolecules 2025 May;307(Pt 3):142072
International journal of biological macromolecules 2025 May;307(Pt 3):142072
YTHDC1 cooperates with the THO complex to prevent RNA-damage-induced DNA breaks.
Tsao N, Lombardi PM, Park A, Olabode J, Rodell R, Sun H, Padmanaban S, Brickner JR, Tsai MS, Pollina EA, Chen CK, Mosammaparast N
Molecular cell 2025 Mar 20;85(6):1085-1100.e9
Molecular cell 2025 Mar 20;85(6):1085-1100.e9
Clinical and functional characterization of recurrent missense variants implicated in THOC6-related intellectual disability.
Mattioli F, Isidor B, Abdul-Rahman O, Gunter A, Huang L, Kumar R, Beaulieu C, Gecz J, Innes M, Mandel JL, Piton A
Human molecular genetics 2019 Mar 15;28(6):952-960
Human molecular genetics 2019 Mar 15;28(6):952-960
Murine leukemia virus uses TREX components for efficient nuclear export of unspliced viral transcripts.
Sakuma T, Tonne JM, Ikeda Y
Viruses 2014 Mar 10;6(3):1135-48
Viruses 2014 Mar 10;6(3):1135-48
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 55178-1-AP( THOC2 Antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The THOC2 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human THOC2. This antibody recognizes human antigen. The THOC2 antibody has been validated for the following applications: ELISA, IP, WB, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-THOC2 (IP:55178-1-AP, 5ug; Detection:55178-1-AP 1:300) with HeLa cells lysate 1800ug.
- Sample type
- cell line
