HPA040262

antibody from Atlas Antibodies

Targeting: CLPX

Immunocytochemistry (Data presented on provider website)

Antibody Data

Product number

HPA040262

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA040262, RRID:AB_10793961

Product name

Anti-CLPX

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human CLPX, Gene description: caseinolytic mitochondrial matrix peptidase chaperone subunit, Validated applications: ICC, Uniprot ID: O76031, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.1 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Dopamine pre-treatment impairs the anti-cancer effect of integrated stress response- and TRAIL pathway-inducing ONC201, ONC206 and ONC212 imipridones in pancreatic, colorectal cancer but not DMG cells

Zhang Y
American Journal of Cancer Research 2024;14(5):2453-2464

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Inactivity of Peptidase ClpP Causes Primary Accumulation of Mitochondrial Disaggregase ClpX with Its Interacting Nucleoid Proteins, and of mtDNA

Key J, Torres-Odio S, Bach N, Gispert S, Koepf G, Reichlmeir M, West A, Prokisch H, Freisinger P, Newman W, Shalev S, Sieber S, Wittig I, Auburger G
Cells 2021;10(12):3354

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The Mouse Heart Mitochondria N Terminome Provides Insights into ClpXP-Mediated Proteolysis

Hofsetz E, Demir F, Szczepanowska K, Kukat A, Kizhakkedathu J, Trifunovic A, Huesgen P
Molecular & Cellular Proteomics 2020;19(8):1330-1345

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A salvage pathway maintains highly functional respiratory complex I

Szczepanowska K, Senft K, Heidler J, Herholz M, Kukat A, Höhne M, Hofsetz E, Becker C, Kaspar S, Giese H, Zwicker K, Guerrero-Castillo S, Baumann L, Kauppila J, Rumyantseva A, Müller S, Frese C, Brandt U, Riemer J, Wittig I, Trifunovic A
Nature Communications 2020;11(1)

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Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation

Ferreira N, Perks K, Rossetti G, Rudler D, Hughes L, Ermer J, Scott L, Kuznetsova I, Richman T, Narayana V, Abudulai L, Shearwood A, Cserne Szappanos H, Tull D, Yeoh G, Hool L, Filipovska A, Rackham O
The EMBO Journal 2019;38(24)

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CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis

Becker C, Kukat A, Szczepanowska K, Hermans S, Senft K, Brandscheid C, Maiti P, Trifunovic A
EMBO reports 2018;19(5)

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Concerted regulation of mitochondrial and nuclear non‐coding RNA s by a dual‐targeted RN ase Z

Siira S, Rossetti G, Richman T, Perks K, Ermer J, Kuznetsova I, Hughes L, Shearwood A, Viola H, Hool L, Rackham O, Filipovska A
EMBO reports 2018;19(10)