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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [12]
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- Product number
- 21537-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- FAM134B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FAM134B antibody (Cat. #21537-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ATF4 links ER stress with reticulophagy in glioblastoma cells.
Endoplasmic reticulum tubules limit the size of misfolded protein condensates.
Sunitinib treatment promotes metastasis of drug-resistant renal cell carcinoma via TFE3 signaling pathway.
STING1 is essential for an RNA-virus triggered autophagy.
Mass spectrometry proteomics reveals a function for mammalian CALCOCO1 in MTOR-regulated selective autophagy.
CALCOCO1 acts with VAMP-associated proteins to mediate ER-phagy.
Intrinsically Disordered Protein TEX264 Mediates ER-phagy.
TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress.
Excessive ER-phagy mediated by the autophagy receptor FAM134B results in ER stress, the unfolded protein response, and cell death in HeLa cells.
Cells Deploy a Two-Pronged Strategy to Rectify Misfolded Proinsulin Aggregates.
Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD.
Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B.
Zielke S, Kardo S, Zein L, Mari M, Covarrubias-Pinto A, Kinzler MN, Meyer N, Stolz A, Fulda S, Reggiori F, Kögel D, van Wijk S
Autophagy 2021 Sep;17(9):2432-2448
Autophagy 2021 Sep;17(9):2432-2448
Endoplasmic reticulum tubules limit the size of misfolded protein condensates.
Parashar S, Chidambaram R, Chen S, Liem CR, Griffis E, Lambert GG, Shaner NC, Wortham M, Hay JC, Ferro-Novick S
eLife 2021 Sep 1;10
eLife 2021 Sep 1;10
Sunitinib treatment promotes metastasis of drug-resistant renal cell carcinoma via TFE3 signaling pathway.
Li L, Zhao S, Liu Z, Zhang N, Pang S, Liu J, Liu C, Fan Y
Cell death & disease 2021 Feb 26;12(2):220
Cell death & disease 2021 Feb 26;12(2):220
STING1 is essential for an RNA-virus triggered autophagy.
Zhang R, Qin X, Yang Y, Zhu X, Zhao S, Zhang Z, Su Q, Zhao Z, Yin X, Meng X, Zhang Z, Li Y
Autophagy 2021 Aug 2;:1-13
Autophagy 2021 Aug 2;:1-13
Mass spectrometry proteomics reveals a function for mammalian CALCOCO1 in MTOR-regulated selective autophagy.
Stefely JA, Zhang Y, Freiberger EC, Kwiecien NW, Thomas HE, Davis AM, Lowry ND, Vincent CE, Shishkova E, Clark NA, Medvedovic M, Coon JJ, Pagliarini DJ, Mercer CA
Autophagy 2020 Dec;16(12):2219-2237
Autophagy 2020 Dec;16(12):2219-2237
CALCOCO1 acts with VAMP-associated proteins to mediate ER-phagy.
Nthiga TM, Kumar Shrestha B, Sjøttem E, Bruun JA, Bowitz Larsen K, Bhujabal Z, Lamark T, Johansen T
The EMBO journal 2020 Aug 3;39(15):e103649
The EMBO journal 2020 Aug 3;39(15):e103649
Intrinsically Disordered Protein TEX264 Mediates ER-phagy.
Chino H, Hatta T, Natsume T, Mizushima N
Molecular cell 2019 Jun 6;74(5):909-921.e6
Molecular cell 2019 Jun 6;74(5):909-921.e6
TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress.
An H, Ordureau A, Paulo JA, Shoemaker CJ, Denic V, Harper JW
Molecular cell 2019 Jun 6;74(5):891-908.e10
Molecular cell 2019 Jun 6;74(5):891-908.e10
Excessive ER-phagy mediated by the autophagy receptor FAM134B results in ER stress, the unfolded protein response, and cell death in HeLa cells.
Liao Y, Duan B, Zhang Y, Zhang X, Xia B
The Journal of biological chemistry 2019 Dec 27;294(52):20009-20023
The Journal of biological chemistry 2019 Dec 27;294(52):20009-20023
Cells Deploy a Two-Pronged Strategy to Rectify Misfolded Proinsulin Aggregates.
Cunningham CN, Williams JM, Knupp J, Arunagiri A, Arvan P, Tsai B
Molecular cell 2019 Aug 8;75(3):442-456.e4
Molecular cell 2019 Aug 8;75(3):442-456.e4
Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD.
Schultz ML, Krus KL, Kaushik S, Dang D, Chopra R, Qi L, Shakkottai VG, Cuervo AM, Lieberman AP
Nature communications 2018 Sep 10;9(1):3671
Nature communications 2018 Sep 10;9(1):3671
Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B.
Lennemann NJ, Coyne CB
Autophagy 2017 Feb;13(2):322-332
Autophagy 2017 Feb;13(2):322-332
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