Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations [0]
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Validation data
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- Product number
- 14731-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14731-1-AP, RRID:AB_11182589
- Product name
- TMEM98 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TMEM98 antibody (Cat. #14731-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Tumor-Suppressor Gene Transmembrane Protein 98 Promotes Proliferation and Inhibits Apoptosis in Ovarian Cancer.
TMEM98 is a negative regulator of FRAT mediated Wnt/ß-catenin signalling.
The microRNA miR-29c-5p inhibits cell proliferation and migration by targeting TMEM98 in head and neck carcinoma.
The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification.
Variants in myelin regulatory factor (MYRF) cause autosomal dominant and syndromic nanophthalmos in humans and retinal degeneration in mice.
Missense Mutations in the Human Nanophthalmos Gene TMEM98 Cause Retinal Defects in the Mouse.
Wu SG, Xu JY, Lei J, Hu M, Zhou J
Frontiers in bioscience (Landmark edition) 2022 Jun 30;27(7):210
Frontiers in bioscience (Landmark edition) 2022 Jun 30;27(7):210
TMEM98 is a negative regulator of FRAT mediated Wnt/ß-catenin signalling.
van der Wal T, Lambooij JP, van Amerongen R
PloS one 2020;15(1):e0227435
PloS one 2020;15(1):e0227435
The microRNA miR-29c-5p inhibits cell proliferation and migration by targeting TMEM98 in head and neck carcinoma.
Li J, Chen W, Luo L, Liao L, Deng X, Wang Y
Aging 2020 Nov 26;13(1):769-781
Aging 2020 Nov 26;13(1):769-781
The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification.
Cross SH, Mckie L, Hurd TW, Riley S, Wills J, Barnard AR, Young F, MacLaren RE, Jackson IJ
PLoS genetics 2020 Apr;16(4):e1008583
PLoS genetics 2020 Apr;16(4):e1008583
Variants in myelin regulatory factor (MYRF) cause autosomal dominant and syndromic nanophthalmos in humans and retinal degeneration in mice.
Garnai SJ, Brinkmeier ML, Emery B, Aleman TS, Pyle LC, Veleva-Rotse B, Sisk RA, Rozsa FW, Ozel AB, Li JZ, Moroi SE, Archer SM, Lin CM, Sheskey S, Wiinikka-Buesser L, Eadie J, Urquhart JE, Black GCM, Othman MI, Boehnke M, Sullivan SA, Skuta GL, Pawar HS, Katz AE, Huryn LA, Hufnagel RB, Genomic Ascertainment Cohort, Camper SA, Richards JE, Prasov L
PLoS genetics 2019 May;15(5):e1008130
PLoS genetics 2019 May;15(5):e1008130
Missense Mutations in the Human Nanophthalmos Gene TMEM98 Cause Retinal Defects in the Mouse.
Cross SH, Mckie L, Keighren M, West K, Thaung C, Davey T, Soares DC, Sanchez-Pulido L, Jackson IJ
Investigative ophthalmology & visual science 2019 Jul 1;60(8):2875-2887
Investigative ophthalmology & visual science 2019 Jul 1;60(8):2875-2887
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