HPA003353

antibody from Atlas Antibodies

Targeting: SLC16A2 AHDS, DXS128, MCT7, MCT8, MRX22, XPCT

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA003353

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA003353, RRID:AB_611613

Product name

Anti-SLC16A2

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human SLC16A2, Gene description: solute carrier family 16, member 2 (thyroid hormone transporter), Alternative Gene Names: AHDS, DXS128, MCT7, MCT8, MRX22, XPCT, Validated applications: IHC, ICC, Uniprot ID: P36021, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.1 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Impaired T3 uptake and action in MCT8-deficient cerebral organoids underlie Allan-Herndon-Dudley syndrome

Salas-Lucia F, Escamilla S, Bianco A, Dumitrescu A, Refetoff S
JCI Insight 2024;9(7)

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Melanocortin-4 Receptor PLC Activation Is Modulated by an Interaction with the Monocarboxylate Transporter 8.

Anthofer L, Gmach P, Uretmen Kagiali ZC, Kleinau G, Rotter J, Opitz R, Scheerer P, Beck-Sickinger AG, Wolf P, Biebermann H, Bechmann I, Kühnen P, Krude H, Paisdzior S
International journal of molecular sciences 2024 Jul 10;25(14)

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Thyroid Hormone Transporters MCT8 and OATP1C1 Are Expressed in Projection Neurons and Interneurons of Basal Ganglia and Motor Thalamus in the Adult Human and Macaque Brains

Wang T, Wang Y, Montero-Pedrazuela A, Prensa L, Guadaño-Ferraz A, Rausell E
International Journal of Molecular Sciences 2023;24(11):9643

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Axonal T3 uptake and transport can trigger thyroid hormone signaling in the brain.

Salas-Lucia F, Fekete C, Sinkó R, Egri P, Rada K, Ruska Y, Gereben B, Bianco AC
eLife 2023 May 19;12

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Canonical TSH Regulation of Cathepsin-Mediated Thyroglobulin Processing in the Thyroid Gland of Male Mice Requires Taar1 Expression.

Qatato M, Szumska J, Skripnik V, Rijntjes E, Köhrle J, Brix K
Frontiers in pharmacology 2018;9:221

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Thyroid Hormone Transporters MCT8 and OATP1C1 Control Skeletal Muscle Regeneration

Mayerl S, Schmidt M, Doycheva D, Darras V, Hüttner S, Boelen A, Visser T, Kaether C, Heuer H, von Maltzahn J
Stem Cell Reports 2018;10(6):1959-1974

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Adeno Associated Virus 9–Based Gene Therapy Delivers a Functional Monocarboxylate Transporter 8, Improving Thyroid Hormone Availability to the Brain of Mct8-Deficient Mice

Iwayama H, Liao X, Braun L, Bárez-López S, Kaspar B, Weiss R, Dumitrescu A, Guadaño-Ferraz A, Refetoff S
Thyroid 2016;26(9):1311-1319

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Age-Dependent Changes of Monocarboxylate Transporter 8 Availability in the Postnatal Murine Retina

Henning Y, Szafranski K
Frontiers in Cellular Neuroscience 2016;10