14392-1-AP

antibody from Proteintech Group

Targeting: YTHDC1 KIAA1966, YT521, YT521-B

Provider product page for 14392-1-AP

Western blot

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Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [77]
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Product number: 14392-1-AP - Provider product page
Provider: Proteintech Group
Product name: YTHDC1 antibody
Antibody type: Polyclonal
Description: KD/KO validated YTHDC1 antibody (Cat. #14392-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

YTHDC1 protein structure - 14392-1-AP shown in red.

Submitted references Low YTHDC1 Expression Upregulates FSCN1 to Promote Nuclear F-Actin Formation and Facilitate Double-strand DNA Breaks Repair in TMZ-Resistant Glioblastoma.

Yang M, Niu W, Wang Y, Chen P, Mu M, Zhang X, Xu B, Hu S, Niu C, Wu P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(13):e13632

FAM20C Modulates Neuronal Differentiation in Hypoxic-Ischemic Brain Damage via KAP1 Phosphorylation and LINE1 RNA m6A-Dependent H3K9me3 Regulation.

Feng CX, Wang M, Li G, Chu SJ, Wu D, Hu XH, Xu LX, Li M, Feng X
Cell proliferation 2026 Jan;59(1):e70073

METTL3-mediated m6A modification of FDX1 confers resistance to cuproptosis and promotes hepatocellular carcinoma progression.

Jiang Q, Peng C, Mao W, Yu Z, Feng Y, Li Y, Zhu J, Zhao J, Liao D, Sun T
Communications biology 2026 Jan 8;9(1):222

Zinc finger protein ZNF33B facilitates Japanese encephalitis virus replication by regulating m(6)A modification on Ifih1 and Irf3 transcripts to antagonize antiviral response.

Du J, Li C, Zhang J, Luo J, Zhang H, Chen H, Li X, Qian P
Cell & bioscience 2026 Jan 4;16(1):13

YTHDC1 modulates the malignant phenotype of retinoblastoma via SQSTM1-mediated autophagy.

Ding J, Sun J, Wang J, Ma R, Xue K, Qian J
Scientific reports 2026 Jan 27;16(1):6292

METTL3-mediated m(6)A modification of CACNA1E promotes osteosarcoma progression and chemoresistance by enhancing WNT7B-mediated Ca(2+) signaling.

Chen C, Xiong K, Liang F, Zhong Y, Qin X, Huang N, Fang Y, Zhu B, Cheng J, Wei Q, Zheng L, Zhao J
Molecular cancer 2026 Jan 19;25(1)

NRAV promotes HCC stemness via the m6A-regulated let-7c-5p/LIN28B axis.

Chen Y, Dai S, Zhuang L, Cai W, Chen H, Zhao J, Zhang F, Chen L, Cheng CS
Cancer gene therapy 2026 Feb;33(2):171-185

Integrated machine learning-based RNA sequencing and single-cell analysis reveal RNA methylation regulation patterns in the immune microenvironment of Alzheimer's disease.

Wu S, Guo T, Zheng X, Gu C, Hu Y, Gu X, Zhou X
Neural regeneration research 2026 Aug 1;21(8):3754-3768

Lactylation-Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22-Mediated Dephosphorylation of NLRP3.

Zhang F, Zeng L, Zou K, Lin K, Yao F, Song J, Zhang S, Feng H, Yang Z, Wang C, Diao H, Kong X, Pan T, Kim J, Duo T, Li L, Bian Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e10192

N(6)-Methyladenosine Reader Protein YTHDC1 Supports Proper Mitotic Progression Partly through Regulation of TPX2-Aurora A Signaling.

Michimori R, Yuki R, Tanaka J, Saito Y, Nakayama Y
Biological & pharmaceutical bulletin 2025;48(5):613-621

METTL16 Promotes Lipid Metabolic Reprogramming and Colorectal Cancer Progression.

Li J, Luo Q, Lu M, Lu C, Xu C, Ding J, Zhan T, Zhu J, Qian M, Lin S, Chang L, Li J, Wang K
International journal of biological sciences 2025;21(11):4782-4797

Integration of bioinformatics and identification of the role of m6A genes in NAFLD.

Ma J, Xu R, Li R, Fu Y, Xu J, Zhou L, Qi Y
PloS one 2025;20(5):e0321757

The m6A modification of SOX18 leads to increased PTX3 and cardiomyocyte pyroptosis in sepsis-induced cardiomyopathy.

Sun H, Qiao X, Peng X, Zhu H, Zhang L, Jiang L, Wang L, Xue C, Yang J, Yi W, Zhang B, Liu J, Duan W
Theranostics 2025;15(8):3532-3550

WDR3 drives pancreatic cancer metastasis by enhancing TGF-α mRNA stability through YTHDC1.

Chen L, You X, Yang C, Zhang Y, Di W, He Q
American journal of cancer research 2025;15(11):4923-4933

RBM15-mediated m6A methylation of Entpd1/CD39 regulates extracellular ATP hydrolysis and alleviates myocardial ischemia-reperfusion injury.

Yan Z, Cao H, Zhang X, Wang Y, Chang Q
International immunopharmacology 2025 Sep 23;162:115141

YTHDF1-mediated m6A modification of TOP2A drives pulmonary hypertension via the PI3K/Akt/mTOR pathway.

Zhang T, Jiang X, Diana C, Zhao X, Huang J, Zhang Y
Cellular signalling 2025 Oct;134:111917

KIAA1429-mediated M(6)A methylation inhibits osteoclast differentiation via stabilizing Lrp4 mRNA and protects against osteoporosis.

Liu J, Fu Q, Li M, Chen J, Xu M, Zhai X, Li S, Li L, Wu X, Xu W, Wang K, Si H
Cellular & molecular biology letters 2025 Oct 27;30(1):123

Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures.

Ding Y, Zuo Y, Zhang B, Fan Y, Xu G, Cheng Z, Ma S, Fang S, Tian A, Gao D, Xu X, Wang Q, Jing Y, Jiang M, Xiong M, Li J, Han Z, Sun S, Wang S, He F, Yang J, Qu J, Zhang W, Liu GH
Cell 2025 Oct 2;188(20):5763-5784.e26

m(6)A deficiency impairs uterine spiral artery remodeling to induce preeclampsia-like symptoms via FGF2.

Liu S, Chen W, Chen J, Liu T, Deng M, Xia L, Li Z, Shi J, Li Y, Peng Y, Ren Q, Miao Z, Wu G, Cao X, Xiao S, Zhang J, Zhong M, Wang L, Xia L
Science China. Life sciences 2025 Nov;68(11):3138-3150

Circular RNA circDhx32 promotes cardiac inflammatory responses in mouse cardiac ischemia-reperfusion injury via binding to FOXO1 competed with AdipoR1.

Si W, Wang CL, Zeng LH, Zhao QY, Xie YT, Yang Y, Diao HT, Song JL, Wu H, Zhang F, Wang Z, Kong X, Jiang WT, Zhang XY, Lin KY, Yao FT, Xiong YT, Pan TF, Pang P, Yang BF, Bian Y
Acta pharmacologica Sinica 2025 Nov;46(11):2924-2937

m6A-mediated silencing of RNF41 by METTL3/YTHDC1 disrupts autophagy to drive intervertebral disc degeneration.

Yao B, Wan L, Deng J, Chen Z, Zhao L, Wang W, Han Z
Cell biology and toxicology 2025 Nov 3;41(1):147

FTO aggravates podocyte injury and diabetic nephropathy progression via m6A-dependent stabilization of ACC1 mRNA and promoting fatty acid metabolism.

Chang K, Hong F, Liu H, Fang Y, Wang H, Song N, Ning Y, Lu Z, Jin S, Dai Y, Ding X
Biochemical pharmacology 2025 May;235:116819

XIAP promotes metastasis of bladder cancer cells by ubiquitylating YTHDC1.

Sun N, Wang S, Liu J, Zhang P, Chang Y, Li H, Zhao K, Liu Y, Huang M, Hu Y, Lin Z, Lu Y, Jiang G, Chen W, Huang C, Jin H
Cell death & disease 2025 Mar 25;16(1):205

Leucine-rich pentatricopeptide repeat-containing protein (LRPPRC)-stabilized lncRNA small nucleolar RNA host gene 15 (Snhg15) modulates hematopoietic injury induced by γ-ray irradiation via m(6)A modification.

Zhang S, Cheng Y, Gao Y, Xu F, Wang Y, Zhang J, Shang Y, Li D, Fan S
Molecular biomedicine 2025 Jun 25;6(1):44

m6A reader IGF2BP2-stabilized lncRNA LHX1-DT inhibits renal cell carcinoma (RCC) cell proliferation and invasion by sponging miR-590-5p.

Zhu C, Li R, You X, Xu J, Wang J, Dong D, Chen X, Wang K
NPJ precision oncology 2025 Jun 17;9(1):193

Arsenic enhances endoplasmic reticulum stress via YTHDC1/AKR1C3 aix to promote the malignant transformation of human urothelial cells.

Chen C, Tong M, Chang Y, Li X, Wang J, Chen L, Huang C, Huang H, Zhao L
Toxicology letters 2025 Jul;410:199-210

FTO-mediated m(6)A demethylation regulates IGFBP3 expression and AKT activation through IMP3-dependent P-body re-localisation in lung cancer.

Wang H, Peng H, Zhang Z, Abulimiti Y, Hu J, Zhou Y, Ji P, Li D
Clinical and translational medicine 2025 Jul;15(7):e70392

METTL14-mediated m6A modification of ETV4 inhibits tumor development in colorectal cancer.

Liao X, Hu T
Mutation research 2025 Jul-Dec;831:111910

M6A-dependent RNA condensation underlies FUS autoregulation and can be harnessed for ALS therapy development.

Huang WP, Kumar V, Yap K, An H, John SJ, Hodgson RE, Avila AS, Day E, Ellis BCS, Chung TH, Lord J, Müller-McNicoll M, Makeyev EV, Shelkovnikova TA
Science advances 2025 Jul 25;11(30):eadx1357

piR-26441 inhibits mitochondrial oxidative phosphorylation and tumorigenesis in ovarian cancer through m6A modification by interacting with YTHDC1.

Yuan J, Xie BM, Ji YM, Bao HJ, Wang JL, Cheng JC, Huang XC, Zhao Y, Chen S
Cell death & disease 2025 Jan 18;16(1):25

USP5 stabilizes YTHDF1 to control cancer immune surveillance through mTORC1-mediated phosphorylation.

Shao N, Xi L, Lv Y, Idris M, Zhang L, Cao Y, Xiang J, Xu X, Ong BX, Zhang Q, Peng X, Yue X, Xu F, Liu C
Nature communications 2025 Feb 3;16(1):1313

The YTHDC1 reader protein recognizes and regulates the lncRNA MEG3 following its METTL3-mediated m(6)A methylation: a novel mechanism early during radiation-induced liver injury.

Song GY, Yu QH, Xing XK, Fan XM, Xu SG, Zhang WB, Wu YY, Zhang N, Chao TZ, Wang F, Ding CS, Guo CY, Ma L, Sun CY, Duan SY, Xu P
Cell death & disease 2025 Feb 24;16(1):127

Mettl3/Eed/Ythdc1 regulatory axis controls endometrial receptivity and function.

Hu X, Li J, Ding C, Jiang J, Xia W, Lu J, Su H, Zhang M, Li H, Liu JL, Lin Y, Meng Q, Huang B
Communications biology 2025 Feb 11;8(1):215

METTL3 promotes peritoneal metastasis of colorectal cancer through regulating m6A modification of NRXN3 mRNA.

Lan TH, Li W, Wang X, Geng YJ, Pang B, Kang LF, Li DY, Pang LY, Zhang XX, Zhang CQ, Wang GQ, Li ZX, Zhou CM, Jiang X, Zhao ZR
iScience 2025 Aug 15;28(8):113165

Nuclear accumulation of YTHDF1 regulates mRNA splicing in the DNA damage response.

Hou J, Gao Y, Han B, Yan S, Wei S, Gao X
Science advances 2025 Apr 18;11(16):eado7660

m6A reader IGF2BP1 facilitates macrophage glycolytic metabolism and fibrotic phenotype by stabilizing THBS1 mRNA to promote pulmonary fibrosis.

Hu Y, Yang L, Huang L, Zeng C, Ren S
Cellular and molecular life sciences : CMLS 2025 Apr 12;82(1):157

LncRNA HOTAIRM1 promotes radioresistance in nasopharyngeal carcinoma by modulating FTO acetylation-dependent alternative splicing of CD44.

Mi J, Wang Y, He S, Qin X, Li Z, Zhang T, Huang W, Wang R
Neoplasia (New York, N.Y.) 2024 Oct;56:101034

Advanced paternal age exacerbates neuroinflammation in offspring via m6A modification-mediated intergenerational inheritance.

Mao Y, Meng Y, Zou K, Qin N, Wang Y, Yan J, Chen P, Cheng Y, Shi W, Zhou C, Chen H, Sheng J, Liu X, Pan J, Huang H
Journal of neuroinflammation 2024 Oct 4;21(1):249

YTHDC1-mediated microRNA maturation is essential for hematopoietic stem cells maintenance.

Zuo H, Liu J, Shen B, Sheng Y, Ju Z, Wang H
Cell death discovery 2024 Oct 16;10(1):439

Functional role of lncRNA MEG3 on pyroptosis through interacting with EZH2 and YTHDC1 in postoperative cognitive dysfunction.

Ma Z, Niu H, Qi H, Li Y
Brain research bulletin 2024 Oct 15;217:111060

m6A-methylase METTL3 promotes retinal angiogenesis through modulation of metabolic reprogramming in RPE cells.

Zhou Q, Liu X, Lu H, Li N, Meng J, Huang J, Zhang Z, Liu J, Fan W, Li W, Li X, Liu X, Zuo H, Yang P, Hou S
Journal of neuroinflammation 2024 Nov 6;21(1):289

Epstein-Barr virus suppresses N(6)-methyladenosine modification of TLR9 to promote immune evasion.

Zhang X, Li Z, Peng Q, Liu C, Wu Y, Wen Y, Zheng R, Xu C, Tian J, Zheng X, Yan Q, Wang J, Ma J
The Journal of biological chemistry 2024 May;300(5):107226

METTL3-mediated m(6)A modification of SOX4 regulates osteoblast proliferation and differentiation via YTHDF3 recognition.

Feng ZW, Peng B, Wang SH, Zhao DC, Wang YB, Yang A, Zhan HW, Sheng XY, Xu LH, Ren XJ, Yang F, Geng B, Xia YY
Cellular signalling 2024 Mar;115:111038

KIAA1429 facilitates metastasis via m6A-YTHDC1-dependent RND3 down-regulation in hepatocellular carcinoma cells.

Shan M, Liu D, Sun L, Yang M, He M, Zhang Y, Xiang L, Lu L, He H, Niu D, Chen L, Li S, Chen A, He F, Wang Y, Lian J
Cancer letters 2024 Mar 1;584:216598

Deficiency of m (6) A RNA methylation promotes ZBP1-mediated cell death.

Li S, Deng X, Pathak D, Basavaraj R, Sun L, Cheng Y, Li JR, Burke M, Britz GW, Cheng C, Gao Y, Weng YL
bioRxiv : the preprint server for biology 2024 Jun 30;

m6A-Mediated IRS1 Regulates the Development of Oral Squamous Cell Carcinoma through p53/Line-1 Signaling.

Xiao Y, Zhu X, Li Q, Wang Z, Zuo Q, Liu X, Tan J
Frontiers in bioscience (Landmark edition) 2024 Jul 19;29(7):257

BIRC5 facilitates cisplatin-chemoresistance in a m(6)A-dependent manner in ovarian cancer.

Fan Y, Pan Y, Jia L, Gu S, Liu B, Mei Z, Lv C, Huang H, Zhu G, Deng Q
Cancer medicine 2024 Jan;13(1):e6811

NAT10 mediated ac4C acetylation driven m(6)A modification via involvement of YTHDC1-LDHA/PFKM regulates glycolysis and promotes osteosarcoma.

Mei Z, Shen Z, Pu J, Liu Q, Liu G, He X, Wang Y, Yue J, Ge S, Li T, Yuan Y, Yang L
Cell communication and signaling : CCS 2024 Jan 17;22(1):51

Autonomous transposons tune their sequences to ensure somatic suppression.

Ilık İA, Glažar P, Tse K, Brändl B, Meierhofer D, Müller FJ, Smith ZD, Aktaş T
Nature 2024 Feb;626(8001):1116-1124

Biogenesis of circRBM33 mediated by N6-methyladenosine and its function in abdominal aortic aneurysm.

Xu Y, Weng X, Qiu J, Wang S
Epigenetics 2024 Dec;19(1):2392401

N6-methyladenosine modified circPAK2 promotes lymph node metastasis via targeting IGF2BPs/VEGFA signaling in gastric cancer.

Ding P, Wu H, Wu J, Li T, He J, Ju Y, Liu Y, Li F, Deng H, Gu R, Zhang L, Guo H, Tian Y, Yang P, Meng N, Li X, Guo Z, Meng L, Zhao Q
Oncogene 2024 Aug;43(34):2548-2563

Alteration of N6-methyladenosine modification profiles in the neutrophilic RNAs following ischemic stroke.

Fan J, Zhong L, Yan F, Li X, Li L, Zhao H, Han Z, Wang R, Tao Z, Zheng Y, Ma Q, Luo Y
Neuroscience 2024 Aug 16;553:56-73

M6A-methylated circPOLR2B forms an R-loop and regulates the biological behavior of glioma stem cells through positive feedback loops.

Lin H, Cui Z, E T, Xu H, Wang D, Wang P, Ruan X, Liu L, Xue Y
Cell death & disease 2024 Aug 1;15(8):554

N(6)-methyladenosine of Spi2a attenuates inflammation and sepsis-associated myocardial dysfunction in mice.

Wang X, Ding Y, Li R, Zhang R, Ge X, Gao R, Wang M, Huang Y, Zhang F, Zhao B, Liao W, Du J
Nature communications 2023 Mar 2;14(1):1185

Exercise Mitigates Endothelial Pyroptosis and Atherosclerosis by Downregulating NEAT1 Through N6-Methyladenosine Modifications.

Yang Q, Chen S, Wang X, Yang X, Chen L, Huang T, Zheng Y, Zheng X, Wu X, Sun Y, Wu J
Arteriosclerosis, thrombosis, and vascular biology 2023 Jun;43(6):910-926

METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.

Wei W, Zhang ZY, Shi B, Cai Y, Zhang HS, Sun CL, Fei YF, Zhong W, Zhang S, Wang C, He B, Jiang GM, Wang H
Journal of experimental & clinical cancer research : CR 2023 Jun 20;42(1):151

METTL3/YTHDC1-medicated m6A modification of circRNA3634 regulates the proliferation and differentiation of antler chondrocytes by miR-124486-5-MAPK1 axis.

Song M, Yao H, Sun Z, Chen D, Xu X, Long G, Wu L, Hu W
Cellular & molecular biology letters 2023 Dec 7;28(1):101

METTL3-mediated m6A mRNA modification was involved in cadmium-induced liver injury.

Li W, Tan M, Wang H, Wang Z, Pang Y, Yang R, Zhong S, Pan X, Chen S, Wang Q, Li D, Xiao Y, Chen W, Chen L
Environmental pollution (Barking, Essex : 1987) 2023 Aug 15;331(Pt 2):121887

Reduction of mRNA m(6)A associates with glucose metabolism via YTHDC1 in human and mice.

Yang K, Sun J, Zhang Z, Xiao M, Ren D, Liu SM
Diabetes research and clinical practice 2023 Apr;198:110607

Reading and writing of mRNA m(6)A modification orchestrate maternal-to-zygotic transition in mice.

Zhu W, Ding Y, Meng J, Gu L, Liu W, Li L, Chen H, Wang Y, Li Z, Li C, Sun Y, Liu Z
Genome biology 2023 Apr 6;24(1):67

m(6)A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress.

Wang L, Zhan G, Maimaitiyiming Y, Su Y, Lin S, Liu J, Su K, Lin J, Shen S, He W, Wang F, Chen J, Sun S, Xue Y, Gu J, Chen X, Zhang J, Zhang L, Wang Q, Chang KJ, Chiou SH, Björklund M, Naranmandura H, Cheng X, Hsu CH
Cell reports 2022 Oct 25;41(4):111546

LncRNA FENDRR with m6A RNA methylation regulates hypoxia-induced pulmonary artery endothelial cell pyroptosis by mediating DRP1 DNA methylation.

Wang X, Li Q, He S, Bai J, Ma C, Zhang L, Guan X, Yuan H, Li Y, Zhu X, Mei J, Gao F, Zhu D
Molecular medicine (Cambridge, Mass.) 2022 Oct 25;28(1):126

A single N6-methyladenosine site regulates lncRNA HOTAIR function in breast cancer cells.

Porman AM, Roberts JT, Duncan ED, Chrupcala ML, Levine AA, Kennedy MA, Williams MM, Richer JK, Johnson AM
PLoS biology 2022 Nov;20(11):e3001885

m(6)A modification of circSPECC1 suppresses RPE oxidative damage and maintains retinal homeostasis.

Chen X, Wang Y, Wang JN, Cao QC, Sun RX, Zhu HJ, Zhang YR, Ji JD, Liu QH
Cell reports 2022 Nov 15;41(7):111671

METTL14-mediated Lnc-LSG1 m6A modification inhibits clear cell renal cell carcinoma metastasis via regulating ESRP2 ubiquitination.

Shen D, Ding L, Lu Z, Wang R, Yu C, Wang H, Zheng Q, Wang X, Xu W, Yu H, Xu L, Wang M, Yu S, Zhu S, Qian J, Xia L, Li G
Molecular therapy. Nucleic acids 2022 Mar 8;27:547-561

Fusobacterium nucleatum reduces METTL3-mediated m(6)A modification and contributes to colorectal cancer metastasis.

Chen S, Zhang L, Li M, Zhang Y, Sun M, Wang L, Lin J, Cui Y, Chen Q, Jin C, Li X, Wang B, Chen H, Zhou T, Wang L, Hsu CH, Zhuo W
Nature communications 2022 Mar 10;13(1):1248

YTHDC1 regulates distinct post-integration steps of HIV-1 replication and is important for viral infectivity.

N'Da Konan S, Ségéral E, Bejjani F, Bendoumou M, Ait Said M, Gallois-Montbrun S, Emiliani S
Retrovirology 2022 Jan 31;19(1):4

Vitamin B(12) Deficiency Dysregulates m6A mRNA Methylation of Genes Involved in Neurological Functions.

Mosca P, Robert A, Alberto JM, Meyer M, Kundu U, Hergalant S, Umoret R, Coelho D, Guéant JL, Leheup B, Dreumont N
Molecular nutrition & food research 2021 Sep;65(17):e2100206

YTHDC1-mediated augmentation of miR-30d in repressing pancreatic tumorigenesis via attenuation of RUNX1-induced transcriptional activation of Warburg effect.

Hou Y, Zhang Q, Pang W, Hou L, Liang Y, Han X, Luo X, Wang P, Zhang X, Li L, Meng X
Cell death and differentiation 2021 Nov;28(11):3105-3124

Integrated analysis of m(6)A mRNA methylation in rats with monocrotaline-induced pulmonary arterial hypertension.

Zeng Y, Huang T, Zuo W, Wang D, Xie Y, Wang X, Xiao Z, Chen Z, Liu Q, Liu N, Xiao Y
Aging 2021 Jul 26;13(14):18238-18256

TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4.

Wang H, Wei W, Zhang ZY, Liu Y, Shi B, Zhong W, Zhang HS, Fang X, Sun CL, Wang JB, Liu LX
Cell death & disease 2021 Dec 17;13(1):3

YTH domain family 2 promotes lung cancer cell growth by facilitating 6-phosphogluconate dehydrogenase mRNA translation.

Sheng H, Li Z, Su S, Sun W, Zhang X, Li L, Li J, Liu S, Lu B, Zhang S, Shan C
Carcinogenesis 2020 Jul 10;41(5):541-550

Expression and Prognostic Significance of m6A-Related Genes in Lung Adenocarcinoma.

Zhang Y, Liu X, Liu L, Li J, Hu Q, Sun R
Medical science monitor : international medical journal of experimental and clinical research 2020 Feb 22;26:e919644

N(6)-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation.

Du J, Liao W, Liu W, Deb DK, He L, Hsu PJ, Nguyen T, Zhang L, Bissonnette M, He C, Li YC
Developmental cell 2020 Dec 21;55(6):737-753.e7

N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication.

Hao H, Hao S, Chen H, Chen Z, Zhang Y, Wang J, Wang H, Zhang B, Qiu J, Deng F, Guan W
Nucleic acids research 2019 Jan 10;47(1):362-374

The m(6)A-methylase complex recruits TREX and regulates mRNA export.

Lesbirel S, Viphakone N, Parker M, Parker J, Heath C, Sudbery I, Wilson SA
Scientific reports 2018 Sep 14;8(1):13827

m(6)A facilitates hippocampus-dependent learning and memory through YTHDF1.

Shi H, Zhang X, Weng YL, Lu Z, Liu Y, Lu Z, Li J, Hao P, Zhang Y, Zhang F, Wu Y, Delgado JY, Su Y, Patel MJ, Cao X, Shen B, Huang X, Ming GL, Zhuang X, Song H, He C, Zhou T
Nature 2018 Nov;563(7730):249-253

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: MCF-7 cells were subjected to SDS PAGE followed by western blot with 14392-1-AP( YTHDC1 Antibody) at dilution of 1:300
Validation comment: WB
Appendix: 14392-1-AP.pdf

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