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Learn19983-1-AP
antibody from Proteintech Group
Targeting: PRKDC
DNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, p350, p460, XRCC7
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 19983-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19983-1-AP, RRID:AB_10642811
- Product name
- DNA-PKcs antibody
- Antibody type
- Polyclonal
- Description
- DNA-PKcs antibody (Cat. #19983-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CircUGGT2 facilitates progression and cisplatin resistance of bladder cancer through nonhomologous end-joining pathway.
CC-115 Mediates GSDME-Dependent Pyroptosis in Lung Adenocarcinoma Through the Akt/Bax Pathway.
Role of ionizing radiation activated NRF2 in lung cancer radioresistance.
Antitumor efficacy of a recombinant EGFR-targeted fusion protein conjugate that induces telomere shortening and telomerase downregulation.
PGC1α Degradation Suppresses Mitochondrial Biogenesis to Confer Radiation Resistance in Glioma.
ITGA2 overexpression inhibits DNA repair and confers sensitivity to radiotherapies in pancreatic cancer.
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response.
DNA damage promotes microtubule dynamics through a DNA-PK-AKT axis for enhanced repair.
Long noncoding RNA lnc-RI regulates DNA damage repair and radiation sensitivity of CRC cells through NHEJ pathway.
HUWE1-dependent DNA-PKcs neddylation modulates its autophosphorylation in DNA damage response.
Targeting Ku86 enhances X-ray-induced radiotherapy sensitivity in serous ovarian cancer cells.
Stem cells from human exfoliated deciduous teeth ameliorate type II diabetic mellitus in Goto-Kakizaki rats.
Flavone protects HBE cells from DNA double-strand breaks caused by PM2.5.
Sensitization of tamoxifen-resistant breast cancer cells by Z-ligustilide through inhibiting autophagy and accumulating DNA damages.
Interaction of cellular proteins with BCL-xL targeted to cytoplasmic inclusion bodies in adenovirus infected cells.
Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis.
IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV.
Lyu F, Huang S, Yan Z, He Q, Liu C, Cheng L, Cong Y, Chen K, Song Y, Xing Y
Cellular signalling 2024 Jul;119:111164
Cellular signalling 2024 Jul;119:111164
CC-115 Mediates GSDME-Dependent Pyroptosis in Lung Adenocarcinoma Through the Akt/Bax Pathway.
Zhang T, Liu MQ, Xie GS, Wu DM, Luo PW, Liu T, Deng SH, Wang YY, He S, Zhou Y, Zhou J, Xu Y
Journal of Cancer 2023;14(8):1350-1361
Journal of Cancer 2023;14(8):1350-1361
Role of ionizing radiation activated NRF2 in lung cancer radioresistance.
Xu Q, Zhang P, Han X, Ren H, Yu W, Hao W, Luo B, Khan MI, Chen N
International journal of biological macromolecules 2023 Jun 30;241:124476
International journal of biological macromolecules 2023 Jun 30;241:124476
Antitumor efficacy of a recombinant EGFR-targeted fusion protein conjugate that induces telomere shortening and telomerase downregulation.
Tao HY, He SM, Zhao CY, Wang Y, Sheng WJ, Zhen YS
International journal of biological macromolecules 2023 Jan 31;226:1088-1099
International journal of biological macromolecules 2023 Jan 31;226:1088-1099
PGC1α Degradation Suppresses Mitochondrial Biogenesis to Confer Radiation Resistance in Glioma.
Zhao M, Li Y, Lu C, Ding F, Xu M, Ge X, Li M, Wang Z, Yin J, Zhang J, Wang X, Ge Z, Xiao H, Xiao Y, Liu H, Liu W, Cao Y, Wang Q, You Y, Wang X, Yang K, Shi Z, Qian X
Cancer research 2023 Apr 4;83(7):1094-1110
Cancer research 2023 Apr 4;83(7):1094-1110
ITGA2 overexpression inhibits DNA repair and confers sensitivity to radiotherapies in pancreatic cancer.
Zhou C, Li S, Bin K, Qin G, Pan P, Ren D, Zhao Y, Xia W, Chen J, Liu J, Wu H, Zhou Y
Cancer letters 2022 Oct 28;547:215855
Cancer letters 2022 Oct 28;547:215855
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response.
Wang W, Li J, Tan J, Wang M, Yang J, Zhang ZM, Li C, Basnakian AG, Tang HW, Perrimon N, Zhou Q
Nature communications 2021 Jan 20;12(1):476
Nature communications 2021 Jan 20;12(1):476
DNA damage promotes microtubule dynamics through a DNA-PK-AKT axis for enhanced repair.
Ma S, Rong Z, Liu C, Qin X, Zhang X, Chen Q
The Journal of cell biology 2021 Feb 1;220(2)
The Journal of cell biology 2021 Feb 1;220(2)
Long noncoding RNA lnc-RI regulates DNA damage repair and radiation sensitivity of CRC cells through NHEJ pathway.
Liu R, Zhang Q, Shen L, Chen S, He J, Wang D, Wang Q, Qi Z, Zhou M, Wang Z
Cell biology and toxicology 2020 Oct;36(5):493-507
Cell biology and toxicology 2020 Oct;36(5):493-507
HUWE1-dependent DNA-PKcs neddylation modulates its autophosphorylation in DNA damage response.
Guo Z, Wang S, Xie Y, Han Y, Hu S, Guan H, Xie D, Bai C, Liu X, Gu Y, Zhou PK, Ma T
Cell death & disease 2020 May 26;11(5):400
Cell death & disease 2020 May 26;11(5):400
Targeting Ku86 enhances X-ray-induced radiotherapy sensitivity in serous ovarian cancer cells.
Ma Q, Kai J, Liu Y, Tong Y, Xie S, Zheng H, Wang Y, Guo L, Lu R
The international journal of biochemistry & cell biology 2020 Apr;121:105705
The international journal of biochemistry & cell biology 2020 Apr;121:105705
Stem cells from human exfoliated deciduous teeth ameliorate type II diabetic mellitus in Goto-Kakizaki rats.
Rao N, Wang X, Zhai Y, Li J, Xie J, Zhao Y, Ge L
Diabetology & metabolic syndrome 2019;11:22
Diabetology & metabolic syndrome 2019;11:22
Flavone protects HBE cells from DNA double-strand breaks caused by PM2.5.
Ren X, Tang Y, Sun J, Feng J, Chen L, Chen H, Zeng S, Chen C, Li X, Zhu H, Zeng Z
Human cell 2018 Apr;31(2):116-126
Human cell 2018 Apr;31(2):116-126
Sensitization of tamoxifen-resistant breast cancer cells by Z-ligustilide through inhibiting autophagy and accumulating DNA damages.
Qi H, Jiang Z, Wang C, Yang Y, Li L, He H, Yu Z
Oncotarget 2017 Apr 25;8(17):29300-29317
Oncotarget 2017 Apr 25;8(17):29300-29317
Interaction of cellular proteins with BCL-xL targeted to cytoplasmic inclusion bodies in adenovirus infected cells.
Subramanian T, Vijayalingam S, Kuppuswamy M, Chinnadurai G
Virology 2015 Sep;483:21-31
Virology 2015 Sep;483:21-31
Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis.
Dong H, Shi Q, Song X, Fu J, Hu L, Xu D, Su C, Xia X, Song E, Song Y
Toxicology and applied pharmacology 2015 Jul 1;286(1):10-6
Toxicology and applied pharmacology 2015 Jul 1;286(1):10-6
IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV.
Monroe KM, Yang Z, Johnson JR, Geng X, Doitsh G, Krogan NJ, Greene WC
Science (New York, N.Y.) 2014 Jan 24;343(6169):428-32
Science (New York, N.Y.) 2014 Jan 24;343(6169):428-32
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DNA-PKcs antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human DNA-PKcs. This antibody recognizes human, mouse antigen. The DNA-PKcs antibody has been validated for the following applications: ELISA, WB analysis.
