ABIN362178

antibody from antibodies-online

Targeting: PRKDC DNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, p350, p460, XRCC7

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN362178

Provider

antibodies-online

Product name

anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (pThr2609) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pThr2609 (V-E-T (p) -Q-A) derived from Human DNA-PK. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human

Host

Rabbit

Epitope

pThr2609

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair.

Ding Q, Reddy YV, Wang W, Woods T, Douglas P, Ramsden DA, Lees-Miller SP, Meek K
Molecular and cellular biology 2003 Aug;23(16):5836-48

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Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks.

Chan DW, Chen BP, Prithivirajsingh S, Kurimasa A, Story MD, Qin J, Chen DJ
Genes & development 2002 Sep 15;16(18):2333-8

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Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase.

Douglas P, Sapkota GP, Morrice N, Yu Y, Goodarzi AA, Merkle D, Meek K, Alessi DR, Lees-Miller SP
The Biochemical journal 2002 Nov 15;368(Pt 1):243-51