Explore
Validate
LearnABIN358415
antibody from antibodies-online
Targeting: PRKDC
DNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, p350, p460, XRCC7
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN358415 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC) (pThr2609) antibody
- Antibody type
- Polyclonal
- Description
- Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- pThr2609
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Novel localization of the DNA-PK complex in lipid rafts: a putative role in the signal transduction pathway of the ionizing radiation response.
Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment.
Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair.
Regulatory interactions between the checkpoint kinase Chk1 and the proteins of the DNA-dependent protein kinase complex.
Interferon regulatory factor-3 is an in vivo target of DNA-PK.
Lucero H, Gae D, Taccioli GE
The Journal of biological chemistry 2003 Jun 13;278(24):22136-43
The Journal of biological chemistry 2003 Jun 13;278(24):22136-43
Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment.
Calsou P, Delteil C, Frit P, Drouet J, Salles B
Journal of molecular biology 2003 Feb 7;326(1):93-103
Journal of molecular biology 2003 Feb 7;326(1):93-103
Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair.
Ding Q, Reddy YV, Wang W, Woods T, Douglas P, Ramsden DA, Lees-Miller SP, Meek K
Molecular and cellular biology 2003 Aug;23(16):5836-48
Molecular and cellular biology 2003 Aug;23(16):5836-48
Regulatory interactions between the checkpoint kinase Chk1 and the proteins of the DNA-dependent protein kinase complex.
Goudelock DM, Jiang K, Pereira E, Russell B, Sanchez Y
The Journal of biological chemistry 2003 Aug 8;278(32):29940-7
The Journal of biological chemistry 2003 Aug 8;278(32):29940-7
Interferon regulatory factor-3 is an in vivo target of DNA-PK.
Karpova AY, Trost M, Murray JM, Cantley LC, Howley PM
Proceedings of the National Academy of Sciences of the United States of America 2002 Mar 5;99(5):2818-23
Proceedings of the National Academy of Sciences of the United States of America 2002 Mar 5;99(5):2818-23
No comments: Submit comment
No validations: Submit validation data