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- Antibody Data
- Antigen structure
- References [13]
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- Validations
- Immunohistochemistry [2]
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- Product number
- 12284-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12284-1-AP, RRID:AB_11182285
- Product name
- PLAC8 antibody
- Antibody type
- Polyclonal
- Description
- PLAC8 antibody (Cat. #12284-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Targeting the CCL28-STAT3-PLAC8 axis to suppress metastasis and remodel tumor microenvironment in colorectal cancer.
Identification and validation of immune and diagnostic biomarkers for interstitial cystitis/painful bladder syndrome by integrating bioinformatics and machine-learning.
PLAC8 attenuates pulmonary fibrosis and inhibits apoptosis of alveolar epithelial cells via facilitating autophagy.
Propagation of monocyte exhaustion memory and underlying mechanisms.
Aberrant PLAC8 expression characterizes glioblastoma with temozolomide resistance and an immunosuppressive microenvironment.
Plac8-ERK pathway modulation of monocyte function in sepsis.
Single-cell RNA profiling reveals classification and characteristics of mononuclear phagocytes in colorectal cancer.
Alleviation of monocyte exhaustion by BCG derivative mycolic acid.
PLAC8 contributes to the malignant behaviors of cervical cancer cells by activating the SOX4-mediated AKT pathway.
Expression profiling of lncRNAs and mRNAs in placental site trophoblastic tumor (PSTT) by microarray.
PLAC8 promotes the autophagic activity and improves the growth priority of human trophoblast cells.
Gut butyrate-producing organisms correlate to Placenta Specific 8 protein: Importance to colorectal cancer progression.
New animal models reveal that coenzyme Q2 (Coq2) and placenta-specific 8 (Plac8) are candidate genes for the onset of type 2 diabetes associated with obesity in rats.
Yang Y, Jiang Q, Zhu Z, Zhang S, Du T, Song S, Jiang X
Frontiers in immunology 2025;16:1610540
Frontiers in immunology 2025;16:1610540
Identification and validation of immune and diagnostic biomarkers for interstitial cystitis/painful bladder syndrome by integrating bioinformatics and machine-learning.
Zhou T, Zhu C, Zhang W, Wu Q, Deng M, Jiang Z, Peng L, Geng H, Tuo Z, Zou C
Frontiers in immunology 2025;16:1511529
Frontiers in immunology 2025;16:1511529
PLAC8 attenuates pulmonary fibrosis and inhibits apoptosis of alveolar epithelial cells via facilitating autophagy.
Sun W, Zhao B, He Z, Chang L, Song W, Chen Y
Communications biology 2025 Jan 14;8(1):48
Communications biology 2025 Jan 14;8(1):48
Propagation of monocyte exhaustion memory and underlying mechanisms.
Wang J, Caldwell BA, Wu Y, Razani B, Li L
Cell communication and signaling : CCS 2025 Dec 5;23(1):525
Cell communication and signaling : CCS 2025 Dec 5;23(1):525
Aberrant PLAC8 expression characterizes glioblastoma with temozolomide resistance and an immunosuppressive microenvironment.
She H, Li TR, Zhao G, Yi L, Liu Q, Liu ZC, Pei HY, Li X, Zuo D, Mao Q, Li Y
Cancer letters 2025 Aug 10;625:217805
Cancer letters 2025 Aug 10;625:217805
Plac8-ERK pathway modulation of monocyte function in sepsis.
Zhang T, Fu JN, Chen GB, Zhang X
Cell death discovery 2024 Jul 3;10(1):308
Cell death discovery 2024 Jul 3;10(1):308
Single-cell RNA profiling reveals classification and characteristics of mononuclear phagocytes in colorectal cancer.
Ji T, Fu H, Wang L, Chen J, Tian S, Wang G, Wang L, Wang Z
PLoS genetics 2024 Feb;20(2):e1011176
PLoS genetics 2024 Feb;20(2):e1011176
Alleviation of monocyte exhaustion by BCG derivative mycolic acid.
Wu Y, Caldwell B, Wang J, Zhang Y, Li L
iScience 2024 Feb 16;27(2):108978
iScience 2024 Feb 16;27(2):108978
PLAC8 contributes to the malignant behaviors of cervical cancer cells by activating the SOX4-mediated AKT pathway.
Deng B, Zhang S, Zhou Y, Zhu Y, Fei J, Li A
Histochemistry and cell biology 2023 May;159(5):439-451
Histochemistry and cell biology 2023 May;159(5):439-451
Expression profiling of lncRNAs and mRNAs in placental site trophoblastic tumor (PSTT) by microarray.
Gan J, Chen Z, Feng X, Wei Z, Zhang S, Du Y, Xu C, Zhao H
International journal of medical sciences 2022;19(1):1-12
International journal of medical sciences 2022;19(1):1-12
PLAC8 promotes the autophagic activity and improves the growth priority of human trophoblast cells.
Feng X, Wei Z, Tao X, Du Y, Wu J, Yu Y, Yu H, Zhao H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Mar;35(3):e21351
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Mar;35(3):e21351
Gut butyrate-producing organisms correlate to Placenta Specific 8 protein: Importance to colorectal cancer progression.
Huang CC, Shen MH, Chen SK, Yang SH, Liu CY, Guo JW, Chang KW, Huang CJ
Journal of advanced research 2020 Mar;22:7-20
Journal of advanced research 2020 Mar;22:7-20
New animal models reveal that coenzyme Q2 (Coq2) and placenta-specific 8 (Plac8) are candidate genes for the onset of type 2 diabetes associated with obesity in rats.
Sasaki D, Kotoh J, Watadani R, Matsumoto K
Mammalian genome : official journal of the International Mammalian Genome Society 2015 Dec;26(11-12):619-29
Mammalian genome : official journal of the International Mammalian Genome Society 2015 Dec;26(11-12):619-29
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human tonsil using 12284-1-AP(PLAC8 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PLAC8 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PLAC8. This antibody recognizes human,mouse,rat antigen. The PLAC8 antibody has been validated for the following applications: ELISA, IHC analysis.
