AF2580

antibody from R&D Systems

Targeting: CD300LB CLM7, TREM5

Western blot (Data presented on provider website)

Antibody Data

Product number

AF2580

Provider

R&D Systems

Product name

Mouse CD300b/LMIR5 Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Detects mouse CD300b/LMIR5 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human LMIR5 is observed and less than 5% cross-reactivity with recombinant human (rh) LMIR1, rhLMIR2, recombinant mouse LMIR3, and rhLMIR6 is observed.

Reactivity

Mouse

Host

Goat

Conjugate

Unconjugated

Antigen sequence

Q3U497


Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

A Functional Signature Ontology (FUSION) screen detects an AMPK inhibitor with selective toxicity toward human colon tumor cells.

Das B, Neilsen BK, Fisher KW, Gehring D, Hu Y, Volle DJ, Kim HS, McCall JL, Kelly DL, MacMillan JB, White MA, Lewis RE
Scientific reports 2018 Feb 28;8(1):3770

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A soluble form of LMIR5/CD300b amplifies lipopolysaccharide-induced lethal inflammation in sepsis.

Yamanishi Y, Takahashi M, Izawa K, Isobe M, Ito S, Tsuchiya A, Maehara A, Kaitani A, Uchida T, Togami K, Enomoto Y, Nakahara F, Oki T, Kajikawa M, Kurihara H, Kitamura T, Kitaura J
Journal of immunology (Baltimore, Md. : 1950) 2012 Aug 15;189(4):1773-9