AF2788

antibody from R&D Systems

Targeting: CD300LF CD300f, CLM1, IGSF13, IREM1, NKIR

Western blot (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

AF2788

Provider

R&D Systems

Product name

Mouse CD300f/LMIR3 Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Detects mouse CD300f/LMIR3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) LMIR1, rhLMIR2, rhLMIR3, recombinant mouse LMIR5, and rhLMIR6 is observed.

Reactivity

Mouse

Host

Goat

Conjugate

Unconjugated

Antigen sequence

Q6SJQ7


Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Mouse LIMR3/CD300f is a negative regulator of the antimicrobial activity of neutrophils.

Ueno K, Urai M, Izawa K, Otani Y, Yanagihara N, Kataoka M, Takatsuka S, Abe M, Hasegawa H, Shimizu K, Kitamura T, Kitaura J, Miyazaki Y, Kinjo Y
Scientific reports 2018 Nov 27;8(1):17406

---

An activating and inhibitory signal from an inhibitory receptor LMIR3/CLM-1: LMIR3 augments lipopolysaccharide response through association with FcRgamma in mast cells.

Izawa K, Kitaura J, Yamanishi Y, Matsuoka T, Kaitani A, Sugiuchi M, Takahashi M, Maehara A, Enomoto Y, Oki T, Takai T, Kitamura T
Journal of immunology (Baltimore, Md. : 1950) 2009 Jul 15;183(2):925-36