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Learn15645-1-AP
antibody from Proteintech Group
Targeting: POM121
DKFZP586G1822, DKFZP586P2220, KIAA0618, POM121A
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [2]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- 15645-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- POM121 antibody
- Antibody type
- Polyclonal
- Description
- POM121 antibody (Cat. #15645-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Altered nuclear envelope homeostasis is a key pathogenic event in C9ORF72-linked ALS/FTD.
A tubule-sheet continuum model for the mechanism of nuclear envelope assembly.
Interactions between FUS and the C-terminal Domain of Nup62 are Sufficient for their Co-phase Separation into Amorphous Assemblies.
Heritable transcriptional defects from aberrations of nuclear architecture.
Cardiovirus leader proteins retarget RSK kinases toward alternative substrates to perturb nucleocytoplasmic traffic.
POM121 promotes proliferation and metastasis in non-small-cell lung cancer through TGF-β/SMAD and PI3K/AKT pathways.
Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway.
Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2.
Sirtori R, Gregoire M, Collins A, Santangelo S, Chatragadda B, Cullen R, Ratti A, Fallini C
bioRxiv : the preprint server for biology 2024 Feb 4;
bioRxiv : the preprint server for biology 2024 Feb 4;
A tubule-sheet continuum model for the mechanism of nuclear envelope assembly.
Zhao G, Liu S, Arun S, Renda F, Khodjakov A, Pellman D
Developmental cell 2023 May 22;58(10):847-865.e10
Developmental cell 2023 May 22;58(10):847-865.e10
Interactions between FUS and the C-terminal Domain of Nup62 are Sufficient for their Co-phase Separation into Amorphous Assemblies.
Kumar MS, Stallworth KM, Murthy AC, Lim SM, Li N, Jain A, Munro JB, Fawzi NL, Lagier-Tourenne C, Bosco DA
Journal of molecular biology 2023 Mar 15;435(6):167972
Journal of molecular biology 2023 Mar 15;435(6):167972
Heritable transcriptional defects from aberrations of nuclear architecture.
Papathanasiou S, Mynhier NA, Liu S, Brunette G, Stokasimov E, Jacob E, Li L, Comenho C, van Steensel B, Buenrostro JD, Zhang CZ, Pellman D
Nature 2023 Jul;619(7968):184-192
Nature 2023 Jul;619(7968):184-192
Cardiovirus leader proteins retarget RSK kinases toward alternative substrates to perturb nucleocytoplasmic traffic.
Lizcano-Perret B, Lardinois C, Wavreil F, Hauchamps P, Herinckx G, Sorgeloos F, Vertommen D, Gatto L, Michiels T
PLoS pathogens 2022 Dec;18(12):e1011042
PLoS pathogens 2022 Dec;18(12):e1011042
POM121 promotes proliferation and metastasis in non-small-cell lung cancer through TGF-β/SMAD and PI3K/AKT pathways.
Guan L, Zhang L, Wang T, Jia L, Zhang N, Yan H, Zhao K
Cancer biomarkers : section A of Disease markers 2021;32(3):293-302
Cancer biomarkers : section A of Disease markers 2021;32(3):293-302
Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway.
Lin YC, Kumar MS, Ramesh N, Anderson EN, Nguyen AT, Kim B, Cheung S, McDonough JA, Skarnes WC, Lopez-Gonzalez R, Landers JE, Fawzi NL, Mackenzie IRA, Lee EB, Nickerson JA, Grunwald D, Pandey UB, Bosco DA
Nature neuroscience 2021 Aug;24(8):1077-1088
Nature neuroscience 2021 Aug;24(8):1077-1088
Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2.
Kane M, Rebensburg SV, Takata MA, Zang TM, Yamashita M, Kvaratskhelia M, Bieniasz PD
eLife 2018 Aug 7;7
eLife 2018 Aug 7;7
No comments: Submit comment
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The POM121 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human POM121. This antibody recognizes human antigen. The POM121 antibody has been validated for the following applications: ELISA, WB analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 15645-1-AP( POM121 Antibody) at dilution of 1:300
- Other comments
- WB
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells using 15645-1-AP( POM121 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
- Other comments
- IF
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemistry of paraffin-embedded human colon tissue slide using 15645-1-AP( POM121 Antibody) at dilution of 1:50 (under 40x lens)
- Other comments
- IHC
