11-9500-42

antibody from Invitrogen Antibodies
Targeting: TIGIT DKFZp667A205, FLJ39873, VSIG9, VSTM3
Provider product page for 11-9500-42

Antibody data

Product number
11-9500-42 - Provider product page
Provider
Invitrogen Antibodies
Product name
TIGIT Monoclonal Antibody (MBSA43), FITC, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The MBSA43 monoclonal antibody reacts with human T cell immunoreceptor with Ig and ITIM domains (TIGIT), which is also known as VSTM3 or WUCAM. This 26 kDa protein is a member of the poliovirus receptor (PVR) family. The expression of TIGIT has been reported on NK cells, regulatory T cells, follicular T helper cells, memory CD4+ T cells, and CD8+ T cells, but it is not expressed on B cells or naive CD4+ T cells. TIGIT may be upregulated on naive CD4+ T cells upon activation. TIGIT can interact with certain members of the PVR and PVR-like families, including CD155, and also mediates the interaction of NK and T cells with antigen presenting cells, fibroblasts, and endothelial cells that express PVR and PVR-like proteins. MBSA43 is reported to crossreact with Rhesus macaque. Applications Reported: This MBSA43 antibody has been reported for use in flow cytometric analysis. Applications Tested: This MBSA43 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Conjugate
Green dye
Isotype
IgG
Antibody clone number
MBSA43
Vial size
100 Tests
Concentration
5 µL/Test
Storage
4° C, store in dark, DO NOT FREEZE!
TIGIT protein structure - 11-9500-42 shown in red.