RA0730

antibody from Oursmab

Targeting: TIGIT DKFZp667A205, FLJ39873, VSIG9, VSTM3

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0730

Provider

Oursmab

Product name

Dargistotug (Biosimilar Reference Antibody) (TIGIT)

Antibody type

Monoclonal

Description

Dargistotug (M-6223) is an investigational fully human IgG1 monoclonal antibody designed as an immune checkpoint inhibitor for the treatment of cancer. It specifically targets TIGIT (T cell immunoreceptor with Ig and ITIM domains), an inhibitory receptor expressed on T cells and NK cells. By blocking TIGIT, it aims to restore anti-tumor immunity and is being evaluated in clinical trials, often in combination with other immunotherapies like PD-1/PD-L1 inhibitors, for various advanced solid tumors.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Dargistotug (Biosimilar Reference Antibody) (TIGIT)-RA0730-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Dargistotug (Biosimilar Reference Antibody) (TIGIT)-RA0730 in a linear range of 3.91-125 ng/mL.