Antibody data

Product number
BS3377 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS3377, RRID:AB_1662166
Product name
FTÉÇ (E285) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 250-300 of Human FTÉÇ.
Description
Mammalian protein farnesyl transferases are heterodimeric proteins containing two nonidentical Ï« and ÉÇ subunits that attach farnesyl residues to a cysteine at the fourth position from the COOH terminus of several proteins, including nuclear lamins and p21Ras proteins. The natural substrates contain the Cys-A-A-Xaa recognition sequence, where the A residues are aliphatic and Xaa represents methionine, serine, glutamine or cysteine. The purified farnesyl transferase is an a-b heterodimer. The ÉÇ subunit, which is known as FTÉÇ, CAAX farnesyltransferase subunit ÉÇ, or Ras proteins prenyltransferase subunit ÉÇ, is a 437 amino acid protein that contains five PFTB repeats and binds the peptide substrate. The Ï« subunit is suspected to participate in formation of a stable complex with the substrate farnesyl pyrophosphate.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
FNTB protein structure - BS3377 shown in red.