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Cell line expression
Protein structure
UPK1A
Uroplakin 1ATSPAN21
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Top validated antibodies |
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| Proteintech Group |  25275-1-AP |
2 references | Polyclonal |
EL
IP
IHC
|
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| NSJ Bioreagents | V7671 |
Monoclonal |
EL
IHC
PA
OA
|
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| Invitrogen Antibodies | 25275-1-AP |
Polyclonal |
IP
IHC
OA
|
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| NovoPro Bioscience Inc. | 116628 |
Polyclonal |
EL
IP
IHC
|
||
| antibodies-online | ABIN955479 |
3 references | Polyclonal |
WB
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|
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