orb386047

antibody from Biorbyt

Targeting: GJB1 CMTX, CMTX1, CX32

Western blot

Immunocytochemistry

Immunohistochemistry

Flow cytometry

Antibody data

Submit

Validation data

Product number: orb386047 - Provider product page
Provider: Biorbyt
Product name: Connexin 32 Antibody / GJB1
Antibody type: Monoclonal
Description: This Ab recognizes a protein of 27-32kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane a-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another.
Reactivity: Human, Mouse, Rat
Host: Mouse
Conjugate: Unconjugated
Antibody clone number: M12.13
Vial size: 20 ug
Storage: Store the Connexin 32 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

GJB1 protein structure - orb386047 shown in red.