MA5-28523

antibody from Invitrogen Antibodies

Targeting: DUSP2 PAC-1

Immunoprecipitation (Recommended by provider)

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

MA5-28523

Provider

Invitrogen Antibodies

Product name

DUSP2 Monoclonal Antibody (PAC-1)

Antibody type

Monoclonal

Antigen

Other

Description

This antibody recognizes an extracellular activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa), also known as integrin alpha IIb beta 3, a receptor which mediates platelet aggregation.

Reactivity

Human

Host

Mouse

Isotype

IgM

Antibody clone number

PAC-1

Vial size

100 µg

Concentration

1 mg/mL

Storage

4° C, do not freeze

References

Submitted references

Rap1 and membrane lipids cooperatively recruit talin to trigger integrin activation.

Bromberger T, Zhu L, Klapproth S, Qin J, Moser M
Journal of cell science 2019 Nov 1;132(21)

Flow cytometry

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Flow cytometry multicolor staining pattern of human lymphocytes stained using anti-human CD41/CD61 (PAC-1) purified Monoclonal antibody (Product # MA5-28523), concentration in sample 8 µg/mL, GAM PE and Hoechst 34580.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Flow cytometry surface staining pattern of PHA stimulated human peripheral whole blood stained using anti-human CD41/CD61 (PAC-1) purified Monoclonal antibody (Product # MA5-28523), concentration in sample 8 µg/mL, GAM PE.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Separation of CD41/CD61 positive platelets (red-filled) from CD41/CD61 negative nucleated cells (black-dashed) in flow cytometry analysis (surface staining) of PHA stimulated human peripheral whole blood stained using anti-human CD41/CD61 (PAC-1) purified Monoclonal antibody (Product # MA5-28523), concentration in sample 8 µg/mL, GAM PE.