POU5F1B

This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development. [provided by RefSeq, Apr 2009]

Description

POU class 5 homeobox 1B

Tissue specificity

Tissue enhanced (choroid plexus)

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Transcription factors

Chromosome

8 (127322183 - 127420066)

Ensembl ID

ENSG00000212993  (ver. 103.38)

Orthologs

-

UniProt

Q06416

neXtProt

NX_Q06416

Human splice variants

Protein structure