Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunohistochemistry [6]
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- Product number
- NBP1-86113 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-86113, RRID:AB_11026385
- Product name
- Rabbit Polyclonal Myotubularin Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human Myotubularin antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references SPEG interacts with myotubularin, and its deficiency causes centronuclear myopathy with dilated cardiomyopathy.
Loss of catalytically inactive lipid phosphatase myotubularin-related protein 12 impairs myotubularin stability and promotes centronuclear myopathy in zebrafish.
Agrawal PB, Pierson CR, Joshi M, Liu X, Ravenscroft G, Moghadaszadeh B, Talabere T, Viola M, Swanson LC, Haliloğlu G, Talim B, Yau KS, Allcock RJ, Laing NG, Perrella MA, Beggs AH
American journal of human genetics 2014 Aug 7;95(2):218-26
American journal of human genetics 2014 Aug 7;95(2):218-26
Loss of catalytically inactive lipid phosphatase myotubularin-related protein 12 impairs myotubularin stability and promotes centronuclear myopathy in zebrafish.
Gupta VA, Hnia K, Smith LL, Gundry SR, McIntire JE, Shimazu J, Bass JR, Talbot EA, Amoasii L, Goldman NE, Laporte J, Beggs AH
PLoS genetics 2013 Jun;9(6):e1003583
PLoS genetics 2013 Jun;9(6):e1003583
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Myotubularin Antibody [NBP1-86113] - Staining of human duodenum shows strong cytoplasmic and membranous positivity in glandular cells (goblet cells).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Myotubularin Antibody [NBP1-86113] - Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules and cells in glomeruli.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Myotubularin Antibody [NBP1-86113] - Staining of human fallopian tube shows moderate to strong membranous positivity in subsets of glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Myotubularin Antibody [NBP1-86113] - Staining of human kidney shows moderate to strong cytoplasmic positivity in cells in tubules.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Myotubularin Antibody [NBP1-86113] - Staining of human small intestine shows moderate to strong membranous positivity in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Myotubularin Antibody [NBP1-86113] - Staining of human testis shows moderate to strong cytoplasmic positivity in subsets of cells in seminiferous ducts.