Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 19254-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19254-1-AP, RRID:AB_10638003
- Product name
- COSMC antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated COSMC antibody (Cat. #19254-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cosmc transfection decreases malignant behavior of Tn+ cells and enhances sensitivity to apoptosis when induced by Apo2L/TRAIL via alteration of O-glycan structure.
The Cosmc-mediated effects of neutrophil elastase on T antigen expression in BEAS-2B cells.
Elevated miR-124-3p in the aging colon disrupts mucus barrier and increases susceptibility to colitis by targeting T-synthase.
COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer.
Ding R, Hu X, Hu W, Du Z, Huang P, Wang M, Sheng J, Ma Y, Wang A, Luan X, Dong M, Cao Q, Zou Y, Hu T
Aging 2021 Oct 13;13(19):23393-23406
Aging 2021 Oct 13;13(19):23393-23406
The Cosmc-mediated effects of neutrophil elastase on T antigen expression in BEAS-2B cells.
Luo L, Zhou X, Kolosov VP, Perelman JM
Respiratory physiology & neurobiology 2020 Oct;281:103496
Respiratory physiology & neurobiology 2020 Oct;281:103496
Elevated miR-124-3p in the aging colon disrupts mucus barrier and increases susceptibility to colitis by targeting T-synthase.
Huang L, Sun TY, Hu LJ, Hu SL, Sun HM, Zhao FQ, Wu B, Yang S, Ji FQ, Zhou DS
Aging cell 2020 Nov;19(11):e13252
Aging cell 2020 Nov;19(11):e13252
COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer.
Hofmann BT, Schlüter L, Lange P, Mercanoglu B, Ewald F, Fölster A, Picksak AS, Harder S, El Gammal AT, Grupp K, Güngör C, Drenckhan A, Schlüter H, Wagener C, Izbicki JR, Jücker M, Bockhorn M, Wolters-Eisfeld G
Molecular cancer 2015 May 29;14:109
Molecular cancer 2015 May 29;14:109
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The COSMC antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human COSMC. This antibody recognizes human,mouse,rat antigen. The COSMC antibody has been validated for the following applications: ELISA, WB analysis.