25395-1-AP
antibody from Proteintech Group
Targeting: FAM20C
DKFZp547D065, DMP4, G-CK, IMAGE:4942737
Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 25395-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- FAM20C antibody
- Antibody type
- Polyclonal
- Description
- FAM20C antibody (Cat. #25395-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Knocking out FAM20C in pre-osteoblasts leads to up-regulation of osteoclast differentiation to affect long bone development.
1,25-Dihydroxyvitamin D3 regulates furin-mediated FGF23 cleavage.
Altered sulfation status of FAM20C-dependent chondroitin sulfate is associated with osteosclerotic bone dysplasia.
Fam20C-mediated phosphorylation of osteopontin is critical for its secretion but dispensable for its action as a cytokine in the activation of hepatic stellate cells in liver fibrogenesis.
Jiang L, Liu X, Liu L, Su L, Lu Z, Zhang H, Guo Y, Zhang W, Zhang S, Xu W, Zhang J, Zhang K, Zhan Y, Xie X, Li R, Dong X, Jin H, Zhang B, Li Y
Gene 2024 Jul 15;915:148396
Gene 2024 Jul 15;915:148396
1,25-Dihydroxyvitamin D3 regulates furin-mediated FGF23 cleavage.
Xie H, Bastepe I, Zhou W, Ay B, Ceraj Z, Portales-Castillo IA, Liu ES, Burnett-Bowie SM, Jüppner H, Rhee EP, Bastepe M, Simic P
JCI insight 2023 Sep 8;8(17)
JCI insight 2023 Sep 8;8(17)
Altered sulfation status of FAM20C-dependent chondroitin sulfate is associated with osteosclerotic bone dysplasia.
Koike T, Mikami T, Tamura JI, Kitagawa H
Nature communications 2022 Dec 26;13(1):7952
Nature communications 2022 Dec 26;13(1):7952
Fam20C-mediated phosphorylation of osteopontin is critical for its secretion but dispensable for its action as a cytokine in the activation of hepatic stellate cells in liver fibrogenesis.
Tibaldi E, Brocca A, Sticca A, Gola E, Pizzi M, Bordin L, Pagano MA, Mazzorana M, Donà G, Violi P, Marin O, Romano A, Angeli P, Carraro A, Brunati AM
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1122-1135
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1122-1135
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse ovary tissue were subjected to SDS PAGE followed by western blot with 25395-1-AP( FAM20C Antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FAM20C antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human FAM20C. This antibody recognizes human, mouse, rat antigen. The FAM20C antibody has been validated for the following applications: ELISA, WB, IHC analysis.