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- Antibody Data
- Antigen structure
- References [9]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 20605-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20605-1-AP, RRID:AB_10732804
- Product name
- HECTD1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HECTD1 antibody (Cat. #20605-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Dorsal root ganglion-derived exosomes deteriorate neuropathic pain by activating microglia via the microRNA-16-5p/HECTD1/HSP90 axis.
Nucleoporin 93, a new substrate of the E3 ubiquitin protein ligase HECTD1, promotes esophageal squamous cell carcinoma progression.
Circ-Bnc2 alleviates neuroinflammation in LPS-stimulated microglial cells to inhibit neuron cell apoptosis through regulating miR-497a-5p/HECTD1 axis.
Proteasomal turnover of the RhoGAP tumor suppressor DLC1 is regulated by HECTD1 and USP7.
Involvement of HECTD1 in LPS-induced astrocyte activation via σ-1R-JNK/p38-FOXJ2 axis.
Legumain is a predictor of all-cause mortality and potential therapeutic target in acute myocardial infarction.
The serine/threonine protein kinase of Streptococcus suis serotype 2 affects the ability of the pathogen to penetrate the blood-brain barrier.
Circular RNA DLGAP4 Ameliorates Ischemic Stroke Outcomes by Targeting miR-143 to Regulate Endothelial-Mesenchymal Transition Associated with Blood-Brain Barrier Integrity.
Condensin I and II Complexes License Full Estrogen Receptor α-Dependent Enhancer Activation.
Xing Y, Li P, Jia Y, Zhang K, Liu M, Jiang J
Biological research 2024 May 15;57(1):28
Biological research 2024 May 15;57(1):28
Nucleoporin 93, a new substrate of the E3 ubiquitin protein ligase HECTD1, promotes esophageal squamous cell carcinoma progression.
Zhang J, Xin Y, Ling X, Liang H, Zhang L, Fang C, Ma J
Human cell 2024 Jan;37(1):245-257
Human cell 2024 Jan;37(1):245-257
Circ-Bnc2 alleviates neuroinflammation in LPS-stimulated microglial cells to inhibit neuron cell apoptosis through regulating miR-497a-5p/HECTD1 axis.
Chen Y, Cao P
Brain and behavior 2023 May;13(5):e2935
Brain and behavior 2023 May;13(5):e2935
Proteasomal turnover of the RhoGAP tumor suppressor DLC1 is regulated by HECTD1 and USP7.
Frey Y, Franz-Wachtel M, Macek B, Olayioye MA
Scientific reports 2022 Mar 23;12(1):5036
Scientific reports 2022 Mar 23;12(1):5036
Involvement of HECTD1 in LPS-induced astrocyte activation via σ-1R-JNK/p38-FOXJ2 axis.
Tang Y, Zhou M, Huang R, Shen L, Yang L, Zhou Z, Ren H, Bai Y
Cell & bioscience 2021 Mar 30;11(1):62
Cell & bioscience 2021 Mar 30;11(1):62
Legumain is a predictor of all-cause mortality and potential therapeutic target in acute myocardial infarction.
Yang H, He Y, Zou P, Hu Y, Li X, Tang L, Zhu Z, Tai S, Tu T, Xiao Y, Chen M, Wu C, Zhou S
Cell death & disease 2020 Nov 26;11(11):1014
Cell death & disease 2020 Nov 26;11(11):1014
The serine/threonine protein kinase of Streptococcus suis serotype 2 affects the ability of the pathogen to penetrate the blood-brain barrier.
Rui L, Weiyi L, Yu M, Hong Z, Jiao Y, Zhe M, Hongjie F
Cellular microbiology 2018 Oct;20(10):e12862
Cellular microbiology 2018 Oct;20(10):e12862
Circular RNA DLGAP4 Ameliorates Ischemic Stroke Outcomes by Targeting miR-143 to Regulate Endothelial-Mesenchymal Transition Associated with Blood-Brain Barrier Integrity.
Bai Y, Zhang Y, Han B, Yang L, Chen X, Huang R, Wu F, Chao J, Liu P, Hu G, Zhang JH, Yao H
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Jan 3;38(1):32-50
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Jan 3;38(1):32-50
Condensin I and II Complexes License Full Estrogen Receptor α-Dependent Enhancer Activation.
Li W, Hu Y, Oh S, Ma Q, Merkurjev D, Song X, Zhou X, Liu Z, Tanasa B, He X, Chen AY, Ohgi K, Zhang J, Liu W, Rosenfeld MG
Molecular cell 2015 Jul 16;59(2):188-202
Molecular cell 2015 Jul 16;59(2):188-202
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 20605-1-AP(HECTD1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using HECTD1 antibody 20605-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-HECTD1 (IP:20605-1-AP, 5ug; Detection:20605-1-AP 1:500) with mouse brain tissue lysate 8000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 20605-1-AP(HECTD1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 20605-1-AP(HECTD1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
