PPP1R14C

The degree of protein phosphorylation is regulated by a balance of protein kinase and phosphatase activities. Protein phosphatase-1 (PP1; see MIM 176875) is a signal-transducing phosphatase that influences neuronal activity, protein synthesis, metabolism, muscle contraction, and cell division. PPP1R14C is an inhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]). [supplied by OMIM, Feb 2010]

Description

Protein phosphatase 1 regulatory inhibitor subunit 14C

Tissue specificity

Tissue enhanced (heart muscle, skeletal muscle, skin , thyroid gland)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

6 (150143044 - 150250392)

Ensembl ID

ENSG00000198729  (ver. 103.38)

Orthologs

Mouse Ppp1r14c: ENSMUSG00000040653

UniProt

Q8TAE6

neXtProt

NX_Q8TAE6

Human splice variants
Mouse splice variants

Protein structure