Antibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- NB100-1617 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-1617, RRID:AB_10002124
- Product name
- Rabbit Polyclonal Vanilloid R1/TRPV1 Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified. Vanilloid Receptor 1
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.05 ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Characterizing the Mechanical Properties of Ectopic Axonal Receptive Fields in Inflamed Nerves and Following Axonal Transport Disruption.
Eugenol Reduces LDL Cholesterol and Hepatic Steatosis in Hypercholesterolemic Rats by Modulating TRPV1 Receptor.
Possible involvement of peripheral TRP channels in the hydrogen sulfide-induced hyperalgesia in diabetic rats.
Novobiocin, a Newly Found TRPV1 Inhibitor, Attenuates the Expression of TRPV1 in Rat Intestine and Intestinal Epithelial Cell Line IEC-6.
Sympatho-excitatory response to pulmonary chemosensitive spinal afferent activation in anesthetized, vagotomized rats.
Activation of transient receptor potential vanilloid-1 (TRPV1) influences how retinal ganglion cell neurons respond to pressure-related stress.
TRPV1 promotes repetitive febrile seizures by pro-inflammatory cytokines in immature brain.
Fufang Kushen injection inhibits sarcoma growth and tumor-induced hyperalgesia via TRPV1 signaling pathways.
Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism.
TRPV1: contribution to retinal ganglion cell apoptosis and increased intracellular Ca2+ with exposure to hydrostatic pressure.
Contribution of TRPV1 to microglia-derived IL-6 and NFkappaB translocation with elevated hydrostatic pressure.
Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane.
An N-terminal variant of Trpv1 channel is required for osmosensory transduction.
Expression and co-expression of VR1, CGRP, and IB4-binding glycoprotein in dorsal root ganglion neurons in rats: differences between the disc afferents and the cutaneous afferents.
Expression and co-expression of VR1, CGRP, and IB4-binding glycoprotein in dorsal root ganglion neurons in rats: differences between the disc afferents and the cutaneous afferents.
Extensive co-localization and heteromultimer formation of the vanilloid receptor-like protein TRPV2 and the capsaicin receptor TRPV1 in the adult rat cerebral cortex.
Localization of vanilloid receptor 1 (TRPV1/VR1)-like immunoreactivity in goldfish and zebrafish retinas: restriction to photoreceptor synaptic ribbons.
Cardiac vanilloid receptor 1-expressing afferent nerves and their role in the cardiogenic sympathetic reflex in rats.
Localization and function of ATP and GABAA receptors expressed by nociceptors and other postnatal sensory neurons in rat.
Distinct roles of P2X receptors in modulating glutamate release at different primary sensory synapses in rat spinal cord.
Subunit modification and association in VR1 ion channels.
Subunit modification and association in VR1 ion channels.
Goodwin G, Bove GM, Dayment B, Dilley A
Neuroscience 2020 Mar 1;429:10-22
Neuroscience 2020 Mar 1;429:10-22
Eugenol Reduces LDL Cholesterol and Hepatic Steatosis in Hypercholesterolemic Rats by Modulating TRPV1 Receptor.
Harb AA, Bustanji YK, Almasri IM, Abdalla SS
Scientific reports 2019 Sep 30;9(1):14003
Scientific reports 2019 Sep 30;9(1):14003
Possible involvement of peripheral TRP channels in the hydrogen sulfide-induced hyperalgesia in diabetic rats.
Roa-Coria JE, Pineda-Farias JB, Barragán-Iglesias P, Quiñonez-Bastidas GN, Zúñiga-Romero Á, Huerta-Cruz JC, Reyes-García JG, Flores-Murrieta FJ, Granados-Soto V, Rocha-González HI
BMC neuroscience 2019 Jan 3;20(1):1
BMC neuroscience 2019 Jan 3;20(1):1
Novobiocin, a Newly Found TRPV1 Inhibitor, Attenuates the Expression of TRPV1 in Rat Intestine and Intestinal Epithelial Cell Line IEC-6.
Liang Q, Lv X, Cai Q, Cai Y, Zhao B, Li G
Frontiers in pharmacology 2018;9:1171
Frontiers in pharmacology 2018;9:1171
Sympatho-excitatory response to pulmonary chemosensitive spinal afferent activation in anesthetized, vagotomized rats.
Shanks J, Xia Z, Lisco SJ, Rozanski GJ, Schultz HD, Zucker IH, Wang HJ
Physiological reports 2018 Jun;6(12):e13742
Physiological reports 2018 Jun;6(12):e13742
Activation of transient receptor potential vanilloid-1 (TRPV1) influences how retinal ganglion cell neurons respond to pressure-related stress.
Sappington RM, Sidorova T, Ward NJ, Chakravarthy R, Ho KW, Calkins DJ
Channels (Austin, Tex.) 2015;9(2):102-13
Channels (Austin, Tex.) 2015;9(2):102-13
TRPV1 promotes repetitive febrile seizures by pro-inflammatory cytokines in immature brain.
Huang WX, Yu F, Sanchez RM, Liu YQ, Min JW, Hu JJ, Bsoul NB, Han S, Yin J, Liu WH, He XH, Peng BW
Brain, behavior, and immunity 2015 Aug;48:68-77
Brain, behavior, and immunity 2015 Aug;48:68-77
Fufang Kushen injection inhibits sarcoma growth and tumor-induced hyperalgesia via TRPV1 signaling pathways.
Zhao Z, Fan H, Higgins T, Qi J, Haines D, Trivett A, Oppenheim JJ, Wei H, Li J, Lin H, Howard OM
Cancer letters 2014 Dec 28;355(2):232-41
Cancer letters 2014 Dec 28;355(2):232-41
Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism.
Starowicz K, Makuch W, Korostynski M, Malek N, Slezak M, Zychowska M, Petrosino S, De Petrocellis L, Cristino L, Przewlocka B, Di Marzo V
PloS one 2013;8(4):e60040
PloS one 2013;8(4):e60040
TRPV1: contribution to retinal ganglion cell apoptosis and increased intracellular Ca2+ with exposure to hydrostatic pressure.
Sappington RM, Sidorova T, Long DJ, Calkins DJ
Investigative ophthalmology & visual science 2009 Feb;50(2):717-28
Investigative ophthalmology & visual science 2009 Feb;50(2):717-28
Contribution of TRPV1 to microglia-derived IL-6 and NFkappaB translocation with elevated hydrostatic pressure.
Sappington RM, Calkins DJ
Investigative ophthalmology & visual science 2008 Jul;49(7):3004-17
Investigative ophthalmology & visual science 2008 Jul;49(7):3004-17
Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane.
Stein AT, Ufret-Vincenty CA, Hua L, Santana LF, Gordon SE
The Journal of general physiology 2006 Nov;128(5):509-22
The Journal of general physiology 2006 Nov;128(5):509-22
An N-terminal variant of Trpv1 channel is required for osmosensory transduction.
Sharif Naeini R, Witty MF, Séguéla P, Bourque CW
Nature neuroscience 2006 Jan;9(1):93-8
Nature neuroscience 2006 Jan;9(1):93-8
Expression and co-expression of VR1, CGRP, and IB4-binding glycoprotein in dorsal root ganglion neurons in rats: differences between the disc afferents and the cutaneous afferents.
Aoki Y, Ohtori S, Takahashi K, Ino H, Douya H, Ozawa T, Saito T, Moriya H
Spine 2005 Jul 1;30(13):1496-500
Spine 2005 Jul 1;30(13):1496-500
Expression and co-expression of VR1, CGRP, and IB4-binding glycoprotein in dorsal root ganglion neurons in rats: differences between the disc afferents and the cutaneous afferents.
Aoki Y, Ohtori S, Takahashi K, Ino H, Douya H, Ozawa T, Saito T, Moriya H
Spine 2005 Jul 1;30(13):1496-500
Spine 2005 Jul 1;30(13):1496-500
Extensive co-localization and heteromultimer formation of the vanilloid receptor-like protein TRPV2 and the capsaicin receptor TRPV1 in the adult rat cerebral cortex.
Liapi A, Wood JN
The European journal of neuroscience 2005 Aug;22(4):825-34
The European journal of neuroscience 2005 Aug;22(4):825-34
Localization of vanilloid receptor 1 (TRPV1/VR1)-like immunoreactivity in goldfish and zebrafish retinas: restriction to photoreceptor synaptic ribbons.
Zimov S, Yazulla S
Journal of neurocytology 2004 Jul;33(4):441-52
Journal of neurocytology 2004 Jul;33(4):441-52
Cardiac vanilloid receptor 1-expressing afferent nerves and their role in the cardiogenic sympathetic reflex in rats.
Zahner MR, Li DP, Chen SR, Pan HL
The Journal of physiology 2003 Sep 1;551(Pt 2):515-23
The Journal of physiology 2003 Sep 1;551(Pt 2):515-23
Localization and function of ATP and GABAA receptors expressed by nociceptors and other postnatal sensory neurons in rat.
Labrakakis C, Tong CK, Weissman T, Torsney C, MacDermott AB
The Journal of physiology 2003 May 15;549(Pt 1):131-42
The Journal of physiology 2003 May 15;549(Pt 1):131-42
Distinct roles of P2X receptors in modulating glutamate release at different primary sensory synapses in rat spinal cord.
Nakatsuka T, Tsuzuki K, Ling JX, Sonobe H, Gu JG
Journal of neurophysiology 2003 Jun;89(6):3243-52
Journal of neurophysiology 2003 Jun;89(6):3243-52
Subunit modification and association in VR1 ion channels.
Rosenbaum T, Awaya M, Gordon SE
BMC neuroscience 2002 Mar 22;3:4
BMC neuroscience 2002 Mar 22;3:4
Subunit modification and association in VR1 ion channels.
Rosenbaum T, Awaya M, Gordon SE
BMC neuroscience 2002 Mar 22;3:4
BMC neuroscience 2002 Mar 22;3:4
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Supportive validation
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- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Vanilloid R1/TRPV1 Antibody [NB100-1617] - TRPV1 Antibody [NB100-1617] - Dorsal Root Ganglion