Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60454 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- TRPV1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human TRPV1.
- Description
- Vanilloid receptor 1 (VR1), also designated capsaicin receptor, is a nonselective cation channel, structurally related to members of the TRP family of ion channels. VR1 is activated by capsaicin, the active ingredient in chili peppers, by heat and by an increase in protons at sites of infection, inflammation and ischemia. By creating moderately acidic conditions, protons are able to lower the temperature threshold for VR1 activation, thus identifying VR1 as a molecular integrator of chemical and physical stimuli that elicit pain. VR1 is expressed in primary sensory neurons and vagal nerves and activated VR1 induces the influx of cations, particularly Ca2+ and Na+ ions. The vanilloid receptor may also be a molecular target for endogenous anandamide, in addition to the cannabinoid receptors, in the nervous and cardiovascular systems.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of TRPV1 pAb at 1:500 dilutionLane1:Hela whole cell lysateLane2:Raw264.7 whole cell lysateLane3:PC12 whole cell lysate