Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 25081-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- PGP antibody
- Antibody type
- Polyclonal
- Description
- PGP antibody (Cat. #25081-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Quantitative chemoproteomics reveals dopamine's protective modification of Tau.
Eupatilin attenuates vemurafenib resistance through inhibition of ABCB1 in melanoma.
ITF6475, a New Histone Deacetylase 6 Inhibitor, Prevents Painful Neuropathy Induced by Paclitaxel.
Combination therapy using Cel-CSO/Taxol NPs for reversing drug resistance in breast cancer through inhibiting PI3K/AKT/NF-κB/HIF-1α pathway.
Establishment and validation of an in vitro liver model based extracellular matrix for hepatotoxicity prediction.
Targeting Metabolic Adaptation of Colorectal Cancer with Vanadium-Doped Nanosystem to Enhance Chemotherapy and Immunotherapy.
Hepatotoxic assessment in a microphysiological system: Simulation of the drug absorption and toxic process after an overdosed acetaminophen on intestinal-liver-on-chip.
Effect of age on metabolomic changes in a model of paclitaxel-induced peripheral neurotoxicity.
A 3D spheroid model of quadruple cell co-culture with improved liver functions for hepatotoxicity prediction.
Design, synthesis and biological evaluation of novel phenylfuran-bisamide derivatives as P-glycoprotein inhibitors against multidrug resistance in MCF-7/ADR cell.
Combination of polythyleneimine regulating autophagy prodrug and Mdr1 siRNA for tumor multidrug resistance.
The inhibitory effect and mechanism of Yi-qi-hua-yu-jie-du decoction on the drug resistance of gastric cancer stem cells based on ABC transporters.
Predicting Panel of Metabolism and Immune-Related Genes for the Prognosis of Human Ovarian Cancer.
Systematic evaluation of multifunctional paclitaxel-loaded polymeric mixed micelles as a potential anticancer remedy to overcome multidrug resistance.
Wang Q, Liu Z, Wang Y, Liu Y, Chen Y, Zhang S, Zeng W, Li D, Yang F, He Z, Xiao W, Liu C, Wang C
Nature chemical biology 2025 Sep;21(9):1341-1350
Nature chemical biology 2025 Sep;21(9):1341-1350
Eupatilin attenuates vemurafenib resistance through inhibition of ABCB1 in melanoma.
Li D, Liu S, Ge Y, Li H, Ke X, Cao D, Deng G, Lu L, Su J
Journal of dermatological science 2025 Sep;119(3):112-121
Journal of dermatological science 2025 Sep;119(3):112-121
ITF6475, a New Histone Deacetylase 6 Inhibitor, Prevents Painful Neuropathy Induced by Paclitaxel.
Cavaletti G, Canta A, Chiorazzi A, Pozzi E, Carozzi V, Meregalli C, Alberti P, Marmiroli P, Scuteri A, Crippa L, Fermi S, Segmani I, Vergani B, Steinkühler C, Licandro SA
Toxics 2025 Sep 10;13(9)
Toxics 2025 Sep 10;13(9)
Combination therapy using Cel-CSO/Taxol NPs for reversing drug resistance in breast cancer through inhibiting PI3K/AKT/NF-κB/HIF-1α pathway.
Zeng H, Zeng X, Wang C, Wang G, Tian Q, Zhao J, Zhao L, Li R, Luo Y, Peng H, Zhang Z, Li X, Wu X
Drug delivery and translational research 2025 Mar;15(3):992-1010
Drug delivery and translational research 2025 Mar;15(3):992-1010
Establishment and validation of an in vitro liver model based extracellular matrix for hepatotoxicity prediction.
Yu Y, Zhong H, Niu Q, Zhao M, Li B, Zhou X
Human & experimental toxicology 2025 Jan-Dec;44:9603271251350797
Human & experimental toxicology 2025 Jan-Dec;44:9603271251350797
Targeting Metabolic Adaptation of Colorectal Cancer with Vanadium-Doped Nanosystem to Enhance Chemotherapy and Immunotherapy.
Cheng Q, Chen Y, Zou D, Li Q, Shi X, Qin Q, Liu M, Wang L, Wang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2409329
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2409329
Hepatotoxic assessment in a microphysiological system: Simulation of the drug absorption and toxic process after an overdosed acetaminophen on intestinal-liver-on-chip.
Yu Y, Sun B, Ye X, Wang Y, Zhao M, Song J, Geng X, Marx U, Li B, Zhou X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Nov;193:115016
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Nov;193:115016
Effect of age on metabolomic changes in a model of paclitaxel-induced peripheral neurotoxicity.
Bonomo R, Canta A, Chiorazzi A, Carozzi VA, Meregalli C, Pozzi E, Alberti P, Frampas CF, Van der Veen DR, Marmiroli P, Skene DJ, Cavaletti G
Journal of the peripheral nervous system : JPNS 2024 Mar;29(1):58-71
Journal of the peripheral nervous system : JPNS 2024 Mar;29(1):58-71
A 3D spheroid model of quadruple cell co-culture with improved liver functions for hepatotoxicity prediction.
Sun B, Liang Z, Wang Y, Yu Y, Zhou X, Geng X, Li B
Toxicology 2024 Jun;505:153829
Toxicology 2024 Jun;505:153829
Design, synthesis and biological evaluation of novel phenylfuran-bisamide derivatives as P-glycoprotein inhibitors against multidrug resistance in MCF-7/ADR cell.
Yang Z, Yang X, Li Y, Cai Y, Yu Y, Zhuang W, Sun X, Li Q, Bao X, Ye X, Tian J, Wei B, Chen J, Wu Q, Zhang H, Mou X, Wang H
European journal of medicinal chemistry 2023 Feb 15;248:115092
European journal of medicinal chemistry 2023 Feb 15;248:115092
Combination of polythyleneimine regulating autophagy prodrug and Mdr1 siRNA for tumor multidrug resistance.
Wang C, Li Z, Xu P, Xu L, Han S, Sun Y
Journal of nanobiotechnology 2022 Nov 11;20(1):476
Journal of nanobiotechnology 2022 Nov 11;20(1):476
The inhibitory effect and mechanism of Yi-qi-hua-yu-jie-du decoction on the drug resistance of gastric cancer stem cells based on ABC transporters.
Huang W, Wen F, Gu P, Liu J, Xia Y, Li Y, Zhou J, Song S, Ruan S, Gu S, Chen X, Shu P
Chinese medicine 2022 Aug 9;17(1):93
Chinese medicine 2022 Aug 9;17(1):93
Predicting Panel of Metabolism and Immune-Related Genes for the Prognosis of Human Ovarian Cancer.
Zhang L, Sun W, Ren W, Zhang J, Xu G
Frontiers in cell and developmental biology 2021;9:690542
Frontiers in cell and developmental biology 2021;9:690542
Systematic evaluation of multifunctional paclitaxel-loaded polymeric mixed micelles as a potential anticancer remedy to overcome multidrug resistance.
Zhang J, Zhao X, Chen Q, Yin X, Xin X, Li K, Qiao M, Hu H, Chen D, Zhao X
Acta biomaterialia 2017 Mar 1;50:381-395
Acta biomaterialia 2017 Mar 1;50:381-395
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 25081-1-AP( PGP Antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The PGP antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PGP. This antibody recognizes human, mouse antigen. The PGP antibody has been validated for the following applications: ELISA, WB, IHC analysis.