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- Antibody Data
- Antigen structure
- References [820]
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- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
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- Product number
- 10094-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10094-1-AP, RRID:AB_2210695
- Product name
- beta Tubulin antibody
- Antibody type
- Polyclonal
- Description
- Beta Tubulin antibody (Cat. #10094-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
Submitted references Metrnl inhibits choroidal neovascularization by attenuating the choroidal inflammation via inactivating the UCHL-1/NF-κB signaling pathway.
Xiasangju alleviate metabolic syndrome by enhancing noradrenaline biosynthesis and activating brown adipose tissue.
TRIM28 facilitates type I interferon activation by targeting TBK1.
Towards modelling tick-virus interactions using the weakly pathogenic Sindbis virus: Evidence that ticks are competent vectors.
Matrix metalloproteinase-8 regulates dendritic cell tolerance in late polymicrobial sepsis via the nuclear factor kappa-B p65/β-catenin pathway.
Global acetylome profiling indicates EPA impedes but OA promotes prostate cancer motility through altered acetylation of PFN1 and FLNA.
Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation.
Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation.
Itaconate inhibits corticosterone-induced necroptosis and neuroinflammation via up-regulating menin in HT22 cells.
PMP2 regulates myelin thickening and ATP production during remyelination.
ER-tethered RNA-binding protein controls NADPH oxidase translation for hydrogen peroxide homeostasis.
EMX2 inhibits clear cell renal cell carcinoma progress via modulating Akt/FOXO3a pathway.
PLCE1 enhances mitochondrial dysfunction to promote GSDME-mediated pyroptosis in doxorubicin-induced cardiotoxicity.
Prevotella melaninogenica disrupted oral epithelial barrier function via myosin light chain kinase.
D-mannose alleviates intervertebral disc degeneration through glutamine metabolism.
PD-1/PD-L1 axis is involved in the interaction between microglial polarization and glioma.
Transcriptomics confirms IRF1 as a key regulator of pyroptosis in diabetic retinopathy.
Targeted degradation of oncogenic BCR-ABL by silencing the gene of NEDD8 E3 ligase RAPSYN.
Esculin suppresses the PERK-eIF2α-CHOP pathway by enhancing SIRT1 expression in oxidative stress-induced rat chondrocytes, mitigating osteoarthritis progression in a rat model.
The disrupting effect of chlormequat chloride on growth hormone is associated with pregnancy.
Crocin Inhibits Orbital Fibroblasts Fibrosis in Thyroid-Associated Ophthalmopathy.
SESN1 functions as a new tumor suppressor gene via Toll-like receptor signaling pathway in neuroblastoma.
OTUD7B knockdown inhibits the proliferation and stemness of breast cancer cells by destabilizing FOXM1.
ACOX1 deficiency-induced lipid metabolic disorder facilitates chronic interstitial fibrosis development in renal allografts.
RSK4 promotes the macrophage recruitment and M2 polarization in esophageal squamous cell carcinoma.
Enhanced glutathione production protects against zearalenone-induced oxidative stress and ferroptosis in female reproductive system.
DTTZ suppresses ferroptosis and reverses mitochondrial dysfunction in normal tissues affected by chemotherapy.
Genome-wide analyses reveal the regulatory roles of DNA methylation-regulated alternative promoter transcripts in breast cancer.
The RNA m(6)A reader IGF2BP3 regulates NFAT1/IRF1 axis-mediated anti-tumor activity in gastric cancer.
Pan-cancer integrated analysis of ANKRD1 expression, prognostic value, and potential implications in cancer.
RFX1 regulates foam cell formation and atherosclerosis by mediating CD36 expression.
Discovery and verification of mmu_Circ_26986/hsa_Circ_0072463 as a potential biomarker and intervention target for sepsis-associated acute kidney injury.
Securin acetylation prevents precocious separase activation and premature sister chromatid separation.
Piperine promotes PI3K/AKT/mTOR-mediated gut-brain autophagy to degrade α-Synuclein in Parkinson's disease rats.
An intranasal influenza virus vector vaccine protects against Helicobacter pylori in mice.
Metformin switches cell death modes to soothe the apical periodontitis via ZBP1.
YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia.
Design, synthesis, and bioactivity evaluation of novel indole-selenide derivatives as P-glycoprotein inhibitors against multi-drug resistance in MCF-7/ADR cell.
Purinergic P2X7 receptor involves in anti-retinal photodamage effects of berberine.
Antidepressant fluoxetine alleviates colitis by reshaping intestinal microenvironment.
Mefloquine enhances the efficacy of anti-PD-1 immunotherapy via IFN-γ-STAT1-IRF1-LPCAT3-induced ferroptosis in tumors.
Electroacupuncture regulates the P2X(7)R-NLRP3 inflammatory cascade to relieve decreased sensation on ocular surface of type 2 diabetic rats with dry eye.
IL-35 ameliorates lipopolysaccharide-induced endothelial dysfunction by inhibiting endothelial-to-mesenchymal transition.
The mechanism of EGFL7 regulating neovascularization in diabetic retinopathy through the PI3K/AKT/VEGFA pathway.
Arecoline induces neurotoxicity in HT22 cells via the promotion of endoplasmic reticulum stress and downregulation of the Nrf2/HO-1 pathway.
LUC7L3 is a downstream factor of SRSF1 and prevents genomic instability.
Conditional deficiency of Rho-associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice.
Bu-Shen-Ning-Xin decoction inhibits macrophage activation to ameliorate premature ovarian insufficiency-related osteoimmune disorder via FSH/FSHR pathway.
A pan-KRAS degrader for the treatment of KRAS-mutant cancers.
Frataxin deficiency shifts metabolism to promote reactive microglia via glucose catabolism.
Transformation of A1/A2 Astrocytes Participates in Brain Ischemic Tolerance Induced by Cerebral Ischemic Preconditioning via Inhibiting NDRG2.
Quercetin prevented diabetic nephropathy by inhibiting renal tubular epithelial cell apoptosis via the PI3K/AKT pathway.
PC (16:0/14:0) ameliorates hyperoxia-induced bronchopulmonary dysplasia by upregulating claudin-1 and promoting alveolar type II cell repair.
Preventive effect of propolis on cognitive decline in Alzheimer's disease model mice.
Genome-scale exon perturbation screens uncover exons critical for cell fitness.
Circular RNA circXPO1 Promotes Multiple Myeloma Progression by Regulating miR-495-3p/DNA Damage-Induced Transcription 4 Axis.
Aristolochic acid I aggravates oxidative stress-mediated apoptosis by inhibiting APE1/Nrf2/HO-1 signaling.
HSP90β regulates EAAT2 expression and participates in ischemia‑reperfusion injury in rats.
Ailanthone synergizes with PARP1 inhibitor in tumour growth inhibition through crosstalk of DNA repair pathways in gastric cancer.
Identification of potential miR‑155 target genes in epidermal immune microenvironment of atopic dermatitis patients and their inflammatory effects on HaCaT cells.
MicroRNA-124 conducts neuroprotective effect via inhibiting AK4/ATF3 after subarachnoid hemorrhage.
Hydrogen sulfide attenuates depression-like behaviours in Parkinson's disease model rats by improving synaptic plasticity in a hippocampal Warburg effect-dependent manner.
Amyloid pathology reduces ELP3 expression and tRNA modifications leading to impaired proteostasis.
Inulin alters gut microbiota to alleviate post-stroke depressive-like behavior associated with the IGF-1-mediated MAPK signaling pathway.
Lycopene protects against ionizing radiation-induced testicular damage by inhibition of apoptosis and mitochondrial dysfunction.
Mitochondria-derived peptide is an effective target for treating streptozotocin induced painful diabetic neuropathy through induction of activated protein kinase/peroxisome proliferator-activated receptor gamma coactivator 1alpha -mediated mitochondrial biogenesis.
TBC1D1 represses glioma progression by altering the integrity of the cytoskeleton.
α-Synuclein reduces acetylserotonin O-methyltransferase mediated melatonin biosynthesis by microtubule-associated protein 1 light chain 3 beta-related degradation pathway.
FBXO28 promotes cell proliferation, migration and invasion via upregulation of the TGF-beta1/SMAD2/3 signaling pathway in ovarian cancer.
DDX60 Promotes Migration and Invasion of Head and Neck Squamous Cell Carcinoma Cell through the NF-κB/IFI27 Signaling Pathway.
Discovery of (quinazolin-6-yl)benzamide derivatives containing a 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety as potent reversal agents against P-glycoprotein-mediated multidrug resistance.
Preliminary study on the role of the CSMD2 gene in bladder cancer.
GDF11 mediates H(2)S to prevent chronic stress-induced cognitive impairment by reducing hippocampal NLRP3/caspase-1-dependent pyroptosis.
Mechanism of synergistic inhibitory effect of benzyl isothiocyanate and zoledronic acid combination on breast cancer induction of osteoclast differentiation.
Aucubin provides protection against cerebral ischaemia-reperfusion injury by suppressing neuronal apoptosis, oxidative stress, and inflammation through the modulation of the AKT-GSK-3β-Nrf2 signal cascade.
Circular RNA RHBDD1 regulates tumorigenicity and ferroptosis in colorectal cancer by mediating the ELAVL1/SCD mRNA interaction.
Single-cell multi-omics profiling of human preimplantation embryos identifies cytoskeletal defects during embryonic arrest.
CDC123 promotes Hepatocellular Carcinoma malignant progression by regulating CDKAL1.
A prognostic model based on Scissor(+) cancer associated fibroblasts identified from bulk and single cell RNA sequencing data in head and neck squamous cell carcinoma.
Discovery of PRDM16-Mediated TRPA1 Induction as the Mechanism for Low Tubulo-Interstitial Fibrosis in Diabetic Kidney Disease.
CEBPA Overexpression Enhances β-Cell Proliferation and Survival.
Warm Acupuncture Reduces Pain and Inflammation in Rats with Lumbar Disc Herniation Induced by Autologous Nucleus Pulposus Transplantation via Regulating p38MAPK/NF-κB Pathway.
Identification of hypoxia- and immune-related biomarkers in patients with ischemic stroke.
Specific inhibition of TET1 in the spinal dorsal horn alleviates inflammatory pain in mice by regulating synaptic plasticity.
Electroacupuncture stimulation ameliorates cognitive impairment induced by long-term high-fat diet by regulating microglial BDNF.
MiR-145-5p overexpression rejuvenates aged adipose stem cells and accelerates wound healing.
Calcitonin gene-related peptide attenuated discogenic low back pain in rats possibly via inhibiting microglia activation.
M2 macrophages promote subconjunctival fibrosis through YAP/TAZ signalling.
Nervous necrosis virus induced vacuolization is a Rab5- and actin-dependent process.
A ROS-responsive and scavenging hydrogel for postoperative abdominal adhesion prevention.
Silencing lncRNA-DARS-AS1 suppresses nonsmall cell lung cancer progression by stimulating miR-302a-3p to inhibit ACAT1 expression.
CRISPR/Cas9 based gene editing of Frizzled class receptor 6 (FZD6) reveals its role in depressive symptoms through disrupting Wnt/β-catenin signaling pathway.
Mechanism of acupuncture in attenuating cerebral ischaemia-reperfusion injury based on nuclear receptor coactivator 4 mediated ferritinophagy.
Icariin alleviates renal inflammation and tubulointerstitial fibrosis via Nrf2-mediated attenuation of mitochondrial damage.
Citric acid promotes SPARC release in pancreatic cancer cells and inhibits the progression of pancreatic tumors in mice on a high-fat diet.
A novel and ubiquitous miRNA-involved regulatory module ensures precise phosphorylation of RNA polymerase II and proper transcription.
Clock knockout in inhibitory neurons reduces predisposition to epilepsy and influences anxiety-like behaviors in mice.
Human amniotic mesenchymal stromal cell-derived exosomes promote neuronal function by inhibiting excessive apoptosis in a hypoxia/ischemia-induced cerebral palsy model: A preclinical study.
HSPA4 upregulation induces immune evasion via ALKBH5/CD58 axis in gastric cancer.
Short-term regulation of TSFM level does not alter amyloidogenesis and mitochondrial function in type-specific cells.
Identification of ferroptosis related genes and pathways in prostate cancer cells under erastin exposure.
Static magnetic field-induced IL-6 secretion in periodontal ligament stem cells accelerates orthodontic tooth movement.
The role of FPR2-mediated ferroptosis in formyl peptide-induced acute lung injury against endothelial barrier damage and protective effect of the mitochondria-derived peptide MOTS-c.
PEI, a new transfection method, augments the inhibitory effect of RBM5 on prostate cancer.
Phosphoglycerate mutase 5 exacerbates liver ischemia-reperfusion injury by activating mitochondrial fission.
Germline USP36 Mutation Confers Resistance to EGFR-TKIs by Upregulating MLLT3 Expression in Patients with Non-Small Cell Lung Cancer.
Penfluroidol Attenuates the Imbalance of the Inflammatory Response by Repressing the Activation of the NLRP3 Inflammasome and Reduces Oxidative Stress via the Nrf2/HO-1 Signaling Pathway in LPS-Induced Macrophages.
S100 Calcium Binding Protein A16 Promotes Cell Proliferation by triggering LATS1 ubiquitin degradation mediated by CUL4A ligase to inhibit Hippo pathway in Glioma development.
XPOT Disruption Suppresses TNBC Growth through Inhibition of Specific tRNA Nuclear Exportation and TTC19 Expression to Induce Cytokinesis Failure.
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
Sodium Butyrate Ameliorates Type 2 Diabetes-Related Sarcopenia Through IL-33-Independent ILC2s/IL-13/STAT3 Signaling Pathway.
Electroacupuncture alleviates perioperative hypothalamus-pituitary-adrenal axis dysfunction via circRNA-miRNA-mRNA networks.
Prognostic values of Annexins and validation of the influence on cell proliferation, migration, and invasion in uveal melanoma.
HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication.
Neutrophil infiltration associated genes on the prognosis and tumor immune microenvironment of lung adenocarcinoma.
Porcine epidemic diarrhea virus causes diarrhea by activating EGFR to regulates NHE3 activity and mobility on plasma membrane.
Weight bearing training alleviates muscle atrophy and pyroptosis of middle-aged rats.
The overexpression of actin related protein 2/3 complex subunit 1B(ARPC1B) promotes the ovarian cancer progression via activation of the Wnt/β-catenin signaling pathway.
Selenomethionine against titanium particle-induced osteolysis by regulating the ROS-dependent NLRP3 inflammasome activation via the β-catenin signaling pathway.
Pan-cancer analysis of Krüppel-like factor 3 and its carcinogenesis in pancreatic cancer.
Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis via the p38/p53/p21 pathway.
Application of a JEG-3 organoid model to study HLA-G function in the trophoblast.
Grouper cGAS is a negative regulator of STING-mediated interferon response.
Tsp-1(+) microglia attenuate retinal neovascularization by maintaining the expression of Smad3 in endothelial cells through exosomes with decreased miR-27a-5p.
Targeting plasmodium α-tubulin-1 to block malaria transmission to mosquitoes.
Inhibition of Hypothalamic FTO Activates STAT3 Signal through ERK1/2 Associated with Reductions in Food Intake and Body Weight.
Combined effects of EMP and RF field on emotional behavior in mice.
The protective role of EP300 in monocrotaline-induced pulmonary hypertension.
Effect of renal denervation on cardiac remodelling and function in rats with chronic intermittent hypoxia.
Aβ Induces Neuroinflammation and Microglial M1 Polarization via cGAS-STING-IFITM3 Signaling Pathway in BV-2 Cells.
DELE1 oligomerization promotes integrated stress response activation.
STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1(+) NK cells.
Optineurin tunes outside-in signaling to regulate lysosome biogenesis and phagocytic clearance in the retina.
Steroidal saponins PPI/CCRIS/PSV induce cell death in pancreatic cancer cell through GSDME-dependent pyroptosis.
MicroRNA miR-223 modulates NLRP3 and Keap1, mitigating lipopolysaccharide-induced inflammation and oxidative stress in bovine mammary epithelial cells and murine mammary glands.
EP300 promotes ferroptosis via HSPA5 acetylation in pancreatic cancer.
Upregulation of HDAC9 in hippocampal neurons mediates depression-like behaviours by inhibiting ANXA2 degradation.
FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer.
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production.
Antigenic variation in hemagglutinin-neuraminidase of Newcastle disease virus isolated from Tibet, China.
Glycogen synthase kinase 3 controls T-cell exhaustion by regulating NFAT activation.
CALHM2 V136G polymorphism reduces astrocytic ATP release and is associated with depressive symptoms and Alzheimer's disease risk.
Acetyl-coenzyme A acetyltransferase 1 promotes brown adipogenesis by activating the AMPK-PGC1α signaling pathway.
A high-throughput Gaussia luciferase reporter assay for screening potential gasdermin E activators against pancreatic cancer.
Plasma exosomes induce inflammatory immune response in patients with acute myocardial infarction.
Dihydromyricetin confers cerebroprotection against subarachnoid hemorrhage via the Nrf2-dependent Prx2 signaling cascade.
Elucidating the pharmacological effects of Compound Kushen injection on MYC-P15-CCND1 signaling pathway in nasopharyngeal carcinoma - An in vitro study.
Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.
Identification and development of Tetra-ARMS PCR-based screening test for a genetic variant of OLA1 (Tyr254Cys) in the human failing heart.
Suppression of the gut microbiota-bile acid-FGF19 axis in patients with atrial fibrillation.
GPR37 promotes colorectal cancer liver metastases by enhancing the glycolysis and histone lactylation via Hippo pathway.
C-IGF1R encoded by cIGF1R acts as a molecular switch to restrict mitophagy of drug-tolerant persister tumour cells in non-small cell lung cancer.
Inhibition of ANXA2 activity attenuates epileptic susceptibility and GluA1 phosphorylation.
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
Mulberry leaf flavonoids activate BAT and induce browning of WAT to improve type 2 diabetes via regulating the AMPK/SIRT1/PGC-1α signaling pathway.
Co-delivery of azithromycin and ibuprofen by ROS-responsive polymer nanoparticles synergistically attenuates the acute lung injury.
FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation.
Lnc-PTCHD4-AS inhibits gastric cancer through MSH2-MSH6 dimerization and ATM-p53-p21 activation.
PDK4 rescues high-glucose-induced senescent fibroblasts and promotes diabetic wound healing through enhancing glycolysis and regulating YAP and JNK pathway.
PHD3 inhibits colon cancer cell metastasis through the occludin-p38 pathway.
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
Screening UFMylation-associated genes in heart tissues of Ufm1-transgenic mice.
Dopamine and cyclic adenosine monophosphate-regulated phosphoprotein with an apparent Mr of 32000 promotes colorectal cancer growth.
Gastrodia elata specific miRNA attenuates neuroinflammation via modulating NF-κB signaling pathway.
Lnc AC016727.1/BACH1/HIF-1 α signal loop promotes the progression of non-small cell lung cancer.
Activation of LXRα attenuates 2-Ethylhexyl diphenyl phosphate (EHDPP) induced placental dysfunction.
Sevoflurane induces neurotoxic effects on developing neurons through the WNK1/NKCC1/Ca(2+) /Drp-1 signalling pathway.
Discovery of a natural small-molecule AMP-activated kinase activator that alleviates nonalcoholic steatohepatitis.
PGC-1α Affects Epileptic Seizures by Regulating Mitochondrial Fusion in Epileptic Rats.
PDLIM3 supports hedgehog signaling in medulloblastoma by facilitating cilia formation.
GNB1 promotes hepatocellular carcinoma progression by targeting BAG2 to activate P38/MAPK signaling.
CB2R activation ameliorates late adolescent chronic alcohol exposure-induced anxiety-like behaviors during withdrawal by preventing morphological changes and suppressing NLRP3 inflammasome activation in prefrontal cortex microglia in mice.
BACH1 deficiency prevents neointima formation and maintains the differentiated phenotype of vascular smooth muscle cells by regulating chromatin accessibility.
IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma.
Estrogen-mediated oar-miR-485-5p targets PPP1R13B to regulate myoblast proliferation in sheep.
VPS35 promotes cell proliferation via EGFR recycling and enhances EGFR inhibitors response in gastric cancer.
Stabilization of nuclear β-catenin by inhibiting KDM2A mediates cerebral ischemic tolerance.
METTL3 promotes SMSCs chondrogenic differentiation by targeting the MMP3, MMP13, and GATA3.
IGF2 inhibits hippocampal over-activated microglia and alleviates depression-like behavior in LPS- treated male mice.
One Stone, Two Birds: A Peptide-Au(I) Infinite Coordination Supermolecule for the Confederate Physical and Biological Radiosensitization in Cancer Radiation Therapy.
Artesunate, a new antimalarial clinical drug, exhibits potent anti-AML activity by targeting the ROS/Bim and TFRC/Fe(2+) pathways.
Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage.
Key domains and residues of the receptor MRGPRX1 recognizing the peptide ligand BAM8-22.
LncRNA SPRY4-IT1 facilitates cell proliferation and angiogenesis of glioma via the miR-101-3p/EZH2/VEGFA signaling axis.
PKCθ Regulates Pituitary Adenoma Bone Invasion by Activating Osteoclast in NF-κB/IL-1β-Dependent Manner.
Deletion of Transglutaminase 2 from Mouse Astrocytes Significantly Improves Their Ability to Promote Neurite Outgrowth on an Inhibitory Matrix.
PDCD6 Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis through the AKT/GSK3β/β-catenin Pathway.
Effects of Spatial Expression of Activating Transcription Factor 4 on the Pathogenicity of Two Phenotypes of Bovine Viral Diarrhea Virus by Regulating the Endoplasmic Reticulum-Mediated Autophagy Process.
1,2,4,5-Tetrazine-tethered probes for fluorogenically imaging superoxide in live cells with ultrahigh specificity.
Mechanism Repositioning Based on Integrative Pharmacology: Anti-Inflammatory Effect of Safflower in Myocardial Ischemia-Reperfusion Injury.
Tibetan medicine Si-Wei-Qiang-Wei Powder ameliorates cholecystitis via inhibiting the production of pro-inflammatory cytokines and regulating the MAPK signaling pathway.
Decellularized brain extracellular matrix slice glioblastoma culture model recapitulates the interaction between cells and the extracellular matrix without a nutrient-oxygen gradient interference.
The tick saliva peptide HIDfsin2 promotes the tick-borne virus SFTSV replication in vitro by enhancing p38 signal pathway.
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.
Magnify is a universal molecular anchoring strategy for expansion microscopy.
Proteomics Profiling Reveals the Molecular Signatures and Potential Therapeutic Targets of Human Nasopharyngeal Carcinoma.
Chromatin remodeling and nucleoskeleton synergistically control osteogenic differentiation in different matrix stiffnesses.
Amyloid futures in the expanding pathology of brain aging and dementia.
Ginsenoside Rb1 improves energy metabolism after spinal cord injury.
Low rumen degradable starch promotes the growth performance of goats by increasing protein synthesis in skeletal muscle via the AMPK-mTOR pathway.
Docosahexaenoic Acid Alters Lipid Metabolism Processes via H3K9ac Epigenetic Modification in Dairy Goat.
Endothelial progenitor cell-derived exosomes promote anti-inflammatory macrophages via SOCS3/JAK2/STAT3 axis and improve the outcome of spinal cord injury.
DnaJC7 specifically regulates tau seeding.
Tumor-Associated Fibroblast-Derived Exosomal circDennd1b Promotes Pituitary Adenoma Progression by Modulating the miR-145-5p/ONECUT2 Axis and Activating the MAPK Pathway.
FBXO28 promotes proliferation, invasion, and metastasis of pancreatic cancer cells through regulation of SMARCC2 ubiquitination.
Scarless wound healing programmed by core-shell microneedles.
Hydrogen sulfide antagonizes formaldehyde-induced ferroptosis via preventing ferritinophagy by upregulation of GDF11 in HT22 cells.
ORP8 inhibits renal cell carcinoma progression by accelerating Stathmin1 degradation and microtubule polymerization.
Exosomes derived from oral squamous cell carcinoma tissue accelerate diabetic wound healing.
The distinct initiation sites and processing activities of TTLL4 and TTLL7 in glutamylation of brain tubulin.
MRPL51 is a downstream target of FOXM1 in promoting the malignant behaviors of lung adenocarcinoma.
Anisomycin inhibits Coxsackievirus B replication by promoting the lysosomal degradation of eEF1A1.
TANGO1 interacts with NRTN to promote hepatocellular carcinoma progression by regulating the PI3K/AKT/mTOR signaling pathway.
Neotuberostemonine and tuberostemonine ameliorate pulmonary fibrosis through suppressing TGF-β and SDF-1 secreted by macrophages and fibroblasts via the PI3K-dependent AKT and ERK pathways.
Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3-NFS1 axis in doxorubicin-induced cardiotoxicity.
Tumor necrosis factor-α reduces adiponectin production by decreasing transcriptional activity of peroxisome proliferator-activated receptor-γ in calf adipocytes.
Expression and Activity of the Transcription Factor CCAAT/Enhancer-Binding Protein β (C/EBPβ) Is Regulated by Specific Pulse-Modulated Radio Frequencies in Oligodendroglial Cells.
Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer.
αKG-driven RNA polymerase II transcription of cyclin D1 licenses malic enzyme 2 to promote cell-cycle progression.
Neobavaisoflavone induces pyroptosis of liver cancer cells via Tom20 sensing the activated ROS signal.
Transcriptional analysis of the expression and prognostic value of lipid droplet-localized proteins in hepatocellular carcinoma.
Triptolide with hepatotoxicity and nephrotoxicity used in local delivery treatment of myocardial infarction by thermosensitive hydrogel.
PPARα is involved in high-fat diet-induced risk avoidance impairment via the regulation of hippocampal BDNF.
Small intestine submucosa as a growth factor attractor promotes peripheral nerve regeneration by enhancing syndecan-3/glial cell line-derived neurotrophic factor (GDNF) signalling:in vivostudy().
Resveratrol-loaded macrophage exosomes alleviate multiple sclerosis through targeting microglia.
Dexmedetomidine attenuates airway inflammation and oxidative stress in asthma via the Nrf2 signaling pathway.
Inhibition of deubiquitinase USP28 attenuates cyst growth in autosomal dominant polycystic kidney disease.
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
Pine pollen extract alleviates ethanol-induced oxidative stress and apoptosis in HepG2 cells via MAPK signaling.
Zcf24, a zinc-finger transcription factor, is required for lactate catabolism and inhibits commensalism in Candida albicans.
Low-Dose Radiation Reduces Doxorubicin-Induced Myocardial Injury Through Mitochondrial Pathways.
Transcription factor ETS proto-oncogene 1 contributes to neuropathic pain by regulating histone deacetylase 1 in primary afferent neurons.
Exosomal-miR-129-2-3p derived from Fusobacterium nucleatum-infected intestinal epithelial cells promotes experimental colitis through regulating TIMELESS-mediated cellular senescence pathway.
Resveratrol Modulates the Redox Response and Bile Acid Metabolism to Maintain the Cholesterol Homeostasis in Fish Megalobrama amblycephala Offered a High-Carbohydrate Diet.
Network Pharmacology and Experimental Verification to Unveil the Mechanism of N-Methyl-D-Aspartic Acid Rescue Humantenirine-Induced Excitotoxicity.
Marine-Derived Natural Product HDYL-GQQ-495 Targets P62 to Inhibit Autophagy.
Jatrorrhizine Suppresses Murine-Norovirus-Triggered N-GSDMD-Dependent Pyroptosis in RAW264.7 Macrophages.
Anti-inflammatory and osteoprotective effects of Shi-Wei-Ru-Xiang pills on collagen-induced arthritis in rats via inhibiting MAPK and STAT3 pathways.
Polydopamine-Decorated PLCL Conduit to Induce Synergetic Effect of Electrical Stimulation and Topological Morphology for Peripheral Nerve Regeneration.
Zinc Promotes Spinal Cord Injury Recovery by Blocking the Activation of NLRP3 Inflammasome Through SIRT3-Mediated Autophagy.
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
3, 14, 19-Triacetyl Andrographolide alleviates the cognitive dysfunction of 3 × Tg-AD mice by inducing initiation and promoting degradation process of autophagy.
Mechanism of YY1 mediating autophagy dependent ferroptosis in PM2.5 induced cardiac fibrosis.
Collagen type Ⅰ-loaded methacrylamide hyaluronic acid hydrogel microneedles alleviate stress urinary incontinence in mice: A novel treatment and prevention strategy.
Bacterial infection promotes tumorigenesis of colorectal cancer via regulating CDC42 acetylation.
Mutation of the attractin gene impairs working memory in rats.
Revealing active components and action mechanism of Fritillariae Bulbus against non-small cell lung cancer through spectrum-effect relationship and proteomics.
TIPE2 deletion improves the therapeutic potential of adoptively transferred NK cells.
Baricitinib Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice by Inhibiting TGF-β1 Signaling Pathway.
Peroxiredoxin-6 Released by Astrocytes Contributes to Neuroapoptosis During Ischemia.
Site-specific phosphorylation of tau impacts mitochondrial biology and response to stressors.
SECTM1 is upregulated in immuno-hot tumors and predicts immunotherapeutic efficacy in multiple cancers.
Hyperactivation of TRPV4 causes the hippocampal pyroptosis pathway and results in cognitive impairment in LPS-treated mice.
Design, synthesis and biological evaluation of novel phenylfuran-bisamide derivatives as P-glycoprotein inhibitors against multidrug resistance in MCF-7/ADR cell.
microRNA-627-5p inhibits colorectal cancer cell proliferation, migration and invasion by targeting Wnt2.
A Novel Prenylflavonoid Icariside I Ameliorates Estrogen Deficiency-Induced Osteoporosis via Simultaneous Regulation of Osteoblast and Osteoclast Differentiation.
Si-Ni-SAN ameliorates obesity through AKT/AMPK/HSL pathway-mediated lipolysis: Network pharmacology and experimental validation.
UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.
Knockout of transient receptor potential ankyrin 1 (TRPA1) modulates the glial phenotype and alleviates perihematomal neuroinflammation after intracerebral hemorrhage in mice via MAPK/NF-κB signaling.
ADAMTS7-Mediated Complement Factor H Degradation Potentiates Complement Activation to Contributing to Renal Injuries.
TBC1 domain family member 25 protects against myocardial apoptosis and the proinflammatory response triggered by ischemia-reperfusion injury through suppression of the TAK1-JNK/p38 MAPK signaling cascade.
White adipose tissue-derived small extracellular vesicles: A new potential therapeutic reagent for accelerating diabetic wound healing.
Exogenous H(2) S promotes ubiquitin-mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S-sulfhydration.
Succinate-induced macrophage polarization and RBP4 secretion promote vascular sprouting in ocular neovascularization.
MRPL48 is a novel prognostic and predictive biomarker of hepatocellular carcinoma.
Piezo1 suppression reduces demyelination after intracerebral hemorrhage.
MicroRNA‑30a‑5p regulates cypermethrin-induced apoptosis of Sertoli cells by targeting KLF9 in vitro.
MicroRNA-144-3p protects against chemotherapy-induced apoptosis of ovarian granulosa cells and activation of primordial follicles by targeting MAP3K9.
CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway.
LncRNA SOCS2-AS1 promotes the progression of papillary thyroid cancer by destabilizing p53 protein.
TM6SF2 reduces lipid accumulation in vascular smooth muscle cells by inhibiting LOX-1 and CD36 expression.
Progressive Thinning of Retinal Nerve Fiber Layer/Ganglion Cell Layer (RNFL/GCL) as Biomarker and Pharmacological Target of Diabetic Retinopathy.
Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.
Apolipoprotein E Polymorphism Impacts White Matter Injury Through Microglial Phagocytosis After Experimental Subarachnoid Hemorrhage.
Systemic treatment with GnRH agonist produces antidepressant-like effects in LPS induced depression male mouse model.
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.
SIRT1 attenuates blood-spinal cord barrier disruption after spinal cord injury by deacetylating p66Shc.
In silico, in vitro and in vivo studies: Dibutyl phthalate promotes prostate cancer cell proliferation by activating Forkhead Box M1 and remission after Natura-α pretreatment.
Vagus nerve stimulation is a potential treatment for ischemic stroke.
Association between F-box-only protein 43 overexpression and hepatocellular carcinoma pathogenesis and prognosis.
Dual-specificity phosphatase 26-dificient neurons are susceptible to oxygen-glucose deprivation/reoxygenation-evoked apoptosis and proinflammatory response by affecting the TAK1-medaited JNK/P38 MAPK pathway.
The dichloromethane extract of Callicarpa longissima rich in diterpenoid phenols exerts anti-inflammatory effect via inhibiting the TLR4/NF-κB signaling pathway.
Enhanced E6AP-mediated ubiquitination of ENO1 via LINC00663 contributes to radiosensitivity of breast cancer by regulating mitochondrial homeostasis.
Novel Benzo Five-Membered Heterocycle Derivatives as P-Glycoprotein Inhibitors: Design, Synthesis, Molecular Docking, and Anti-Multidrug Resistance Activity.
Acinous cell AR42J-derived exosome miR125b-5p promotes acute pancreatitis exacerbation by inhibiting M2 macrophage polarization via PI3K/AKT signaling pathway.
Targeting Chondroitin Sulphate Synthase 1 (Chsy1) Promotes Axon Growth Following Neurorrhaphy by Suppressing Versican Accumulation.
A conditional knockout rat resource of mitochondrial protein-coding genes via a DdCBE-induced premature stop codon.
ME2 Promotes Hepatocellular Carcinoma Cell Migration through Pyruvate.
TET1-TRPV4 Signaling Contributes to Bone Cancer Pain in Rats.
Antidepressant-like effect of acute dose of Naringin involves suppression of NR1 and activation of protein kinase A/cyclic adenosine monophosphate response element-binding protein/brain-derived neurotrophic factor signaling in hippocampus.
The preventive and therapeutic effect of repetitive transcranial magnetic stimulation on radiation-induced brain injury in mice.
Selective Inhibition of Histone Deacetylase Class IIa With MC1568 Ameliorates Podocyte Injury.
Copy Number Analyses Identified a Novel Gene: APOBEC3A Related to Lipid Metabolism in the Pathogenesis of Preeclampsia.
Activation of Transcription Factor EB Is Associated With Adipose Tissue Lipolysis in Dairy Cows With Subclinical Ketosis.
The Hair Growth-Promoting Effect of Gardenia florida Fruit Extract and Its Molecular Regulation.
Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK.
Epoxyeicosatrienoic Acids Inhibit the Activation of Murine Fibroblasts by Blocking the TGF-β1-Smad2/3 Signaling in a PPARγ-Dependent Manner.
Identifying Potential Tumor Antigens and Antigens-Related Subtypes in Hepatocellular Carcinoma for mRNA Vaccine Development.
Dexpramipexole Attenuates White Matter Injury to Facilitate Locomotion and Motor Coordination Recovery via Reducing Ferroptosis after Intracerebral Hemorrhage.
Extracellular CIRP Upregulates Proinflammatory Cytokine Expression via the NF-kappaB and ERK1/2 Signaling Pathways in Psoriatic Keratinocytes.
Metformin Protects against Spinal Cord Injury and Cell Pyroptosis via AMPK/NLRP3 Inflammasome Pathway.
Prediction of Prognosis and Recurrence of Bladder Cancer by ECM-Related Genes.
Hyperhomocysteinemia Promotes Cardiac Hypertrophy in Hypertension.
Repeated Yueju, But Not Fluoxetine, Induced Sustained Antidepressant Activity in a Mouse Model of Chronic Learned Helplessness: Involvement of CaMKII Signaling in the Hippocampus.
Silencing lncRNA 93358 Inhibits the Apoptosis of Myocardial Cells in Myocardial Infarction Rats by Inducing the Expression of SLC8A1.
MiR-3571 modulates the proliferation and migration of vascular smooth muscle cells by targeting claudin 1.
Caspase-1-mediated extracellular vesicles derived from pyroptotic alveolar macrophages promote inflammation in acute lung injury.
Diprotin A TFA Exerts Neurovascular Protection in Ischemic Cerebral Stroke.
Inhibiting Sphingosine 1-Phosphate Receptor Subtype 3 Attenuates Brain Damage During Ischemia-Reperfusion Injury by Regulating nNOS/NO and Oxidative Stress.
BRD7 Stabilizes P53 via Dephosphorylation of MDM2 to Inhibit Tumor Growth in Breast Cancer Harboring Wild-type P53.
Qing-Re-Xiao-Zheng-Yi-Qi formula relieves kidney damage and activates mitophagy in diabetic kidney disease.
Therapeutic effects of shaogan fuzi decoction in rheumatoid arthritis: Network pharmacology and experimental validation.
Cuproptosis status affects treatment options about immunotherapy and targeted therapy for patients with kidney renal clear cell carcinoma.
Optical Visualization of Red-GQDs' Organelles Distribution and Localization in Living Cells.
ANXA1: An Important Independent Prognostic Factor and Molecular Target in Glioma.
Oar-miR-432 Regulates Fat Differentiation and Promotes the Expression of BMP2 in Ovine Preadipocytes.
Sperm Autoantigenic Protein 17 Predicts the Prognosis and the Immunotherapy Response of Cancers: A Pan-Cancer Analysis.
Sleeve Gastrectomy-Induced AMPK Activation Attenuates Diabetic Cardiomyopathy by Maintaining Mitochondrial Homeostasis via NR4A1 Suppression in Rats.
S1PR3, as a Core Protein Related to Ischemic Stroke, is Involved in the Regulation of Blood-Brain Barrier Damage.
Punicalagin Alleviates Psoriasis by Inhibiting NF-κB-Mediated IL-1β Transcription and Caspase-1-Regulated IL-1β Secretion.
Avasimibe Alleviates Disruption of the Airway Epithelial Barrier by Suppressing the Wnt/β-Catenin Signaling Pathway.
Identification of super-enhancer-driven peptidyl arginine deiminases as potential biomarkers and therapeutic targets for osimertinib-resistant non-small cell lung cancer.
Small RNA perspective of physical exercise-related improvement of male reproductive dysfunction due to obesity.
Berberine prevents lethal EV71 neurological infection in newborn mice.
X-box binding protein 1: A new metabolic mediator and drug target of metformin?
Prrx1 promotes resistance to temozolomide by upregulating ABCC1 and inducing vasculogenic mimicry in glioma.
Interleukin 33-mediated inhibition of A-type K(+) channels induces sensory neuronal hyperexcitability and nociceptive behaviors in mice.
The PROTAC selectively degrading Bcl-x(L) represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while sparing bone growth.
A novel HCC prognosis predictor PDSS1 affects the cell cycle through the STAT3 signaling pathway in HCC.
The Synergistic Cytotoxic Effects of GW5074 and Sorafenib by Impacting Mitochondrial Functions in Human Colorectal Cancer Cell Lines.
Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6.
AQP5 Is a Novel Prognostic Biomarker in Pancreatic Adenocarcinoma.
Transient Receptor Potential Cation Channel Subfamily V Member 1 Expression Promotes Chemoresistance in Non-Small-Cell Lung Cancer.
Label-free LC-MS/MS proteomics analyses reveal CLIC1 as a predictive biomarker for bladder cancer staging and prognosis.
HIF-1/2α-Activated RNF146 Enhances the Proliferation and Glycolysis of Hepatocellular Carcinoma Cells via the PTEN/AKT/mTOR Pathway.
Chicken ISG12(2) attenuates Newcastle disease virus and enhances the efficiency of Newcastle disease vaccine via activating immune pathways.
Nav1.8 in keratinocytes contributes to ROS-mediated inflammation in inflammatory skin diseases.
Silica nanoparticle exposure inhibits surfactant protein A and B in A549 cells through ROS-mediated JNK/c-Jun signaling pathway.
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Vagus nerve stimulation promotes the M1-to-M2 transition via inhibition of TLR4/NF-κB in microglial to rescue the reperfusion injury.
UFL1 alleviates ER stress and apoptosis stimulated by LPS via blocking the ferroptosis pathway in human granulosa-like cells.
Elevated phosphorylation of EGFR in NSCLC due to mutations in PTPRH.
Deficiency of proline/serine-rich coiled-coil protein 1 (PSRC1) accelerates trimethylamine N-oxide-induced atherosclerosis in ApoE(-/-) mice.
Phosphorylation of Ser82 on IRF3 acts as negative-feedback regulation of IRF3-dependent innate immunity.
Gut microbiota-derived metabolites contribute negatively to hindgut barrier function development at the early weaning goat model.
Metabolic Syndrome Ameliorated by 4-Methylesculetin by Reducing Hepatic Lipid Accumulation.
Proteomic and Biochemical Approaches Elucidate the Role of Millimeter-Wave Irradiation in Wheat Growth under Flooding Stress.
Acid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis.
Supramolecular Hydrogel-Wrapped Gingival Mesenchymal Stem Cells in Cutaneous Radiation Injury.
Proteomic characterization of gastric cancer response to chemotherapy and targeted therapy reveals new therapeutic strategies.
Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model.
Role of PARP-1 in Human Cytomegalovirus Infection and Functional Partners Encoded by This Virus.
MARCH1 promotes the growth and maintaining of stem cell-like characteristics of gastric cancer cells by activating the Wnt/β-catenin signaling pathway.
LncRNA ALKBH3-AS1 enhances ALKBH3 mRNA stability to promote hepatocellular carcinoma cell proliferation and invasion.
Proteome-wide analysis of the hippocampus in adolescent male mice with learning and memory impairment caused by chronic ethanol exposure.
The phytochemical constituents and protective effect of Fritillaria hupehensis on acute lung injury.
Reticulocalbin3: A Ca(2+) homeostasis regulator that promotes esophageal squamous cell carcinoma progression and cisplatin resistance.
Targeting PERK mediated endoplasmic reticulum stress attenuates neuroinflammation and alleviates lipopolysaccharide-induced depressive-like behavior in male mice.
Local Application of Krill Oil Accelerates the Healing of Artificially Created Wounds in Diabetic Mice.
Hepatic inactivation of murine Surf4 results in marked reduction in plasma cholesterol.
Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood-Milk Barrier.
Knockdown of CLAUDIN-6 Inhibited Apoptosis and Induced Proliferation of Bovine Cumulus Cells.
Hypoxia-Regulated lncRNA USP2-AS1 Drives Head and Neck Squamous Cell Carcinoma Progression.
Angiotensin-converting enzyme 2 identifies immuno-hot tumors suggesting angiotensin-(1-7) as a sensitizer for chemotherapy and immunotherapy in breast cancer.
Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis.
TRPM8 contributes to sex dimorphism by promoting recovery of normal sensitivity in a mouse model of chronic migraine.
The role of E3 ubiquitin ligase WWP2 and the regulation of PARP1 by ubiquitinated degradation in acute lymphoblastic leukemia.
Kaempferol prevents angiogenesis of rat intestinal microvascular endothelial cells induced by LPS and TNF-α via inhibiting VEGF/Akt/p38 signaling pathways and maintaining gut-vascular barrier integrity.
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
Synthetic Retinoid Kills Drug-Resistant Cancer Stem Cells via Inducing RARγ-Translocation-Mediated Tension Reduction and Chromatin Decondensation.
Knockdown of TTC9 inhibits the proliferation, migration and invasion, but induces the apoptosis of lung adenocarcinoma cells.
Overexpression of PYGO1 promotes early cardiac lineage development in human umbilical cord mesenchymal stromal/stem cells by activating the Wnt/β-catenin pathway.
Homozygous missense mutation in CCDC155 disrupts the transmembrane distribution of CCDC155 and SUN1, resulting in non-obstructive azoospermia and premature ovarian insufficiency in humans.
Hydrogen improves exercise endurance in rats by promoting mitochondrial biogenesis.
Hyperglycemia promotes myocardial dysfunction via the ERS-MAPK10 signaling pathway in db/db mice.
Regulation of cohesin-mediated chromosome folding by PDS5 in mammals.
Discovery of a novel Pleuromutilin derivative as anti-IPF lead compound via high-throughput assay.
Functional Attenuation of UCP1 as the Potential Mechanism for a Thickened Blubber Layer in Cetaceans.
Trichostatin D as a Novel KLF2 Activator Attenuates TNFα-Induced Endothelial Inflammation.
Differential requirements of IQUB for the assembly of radial spoke 1 and the motility of mouse cilia and flagella.
Hydrogen Sulfide Regulates SERCA2a Ubiquitylation via Muscle RING Finger-1 S-Sulfhydration to Affect Cardiac Contractility in db/db Mice.
mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters.
NAP1L5 targeting combined with MYH9 Inhibit HCC progression through PI3K/AKT/mTOR signaling pathway.
Inhibitory effect of tanshinone IIA, resveratrol and silibinin on enterovirus 68 production through inhibiting ATM and DNA-PK pathway.
cGAS-STING mediates cytoplasmic mitochondrial-DNA-induced inflammatory signal transduction during accelerated senescence of pancreatic β-cells induced by metabolic stress.
SMAD4 Inhibits Granulosa Cell Apoptosis via the miR-183-96-182 Cluster and FoxO1 Axis.
Type IIB PKA is highly expressed in β cells and controls cell proliferation via regulating Cyclin D1 expression.
The roles of grouper TAK1 in regulating the infection of Singapore grouper iridovirus.
Ubiquitin-like modifier 1 ligating enzyme 1 relieves cisplatin-induced premature ovarian failure by reducing endoplasmic reticulum stress in granulosa cells.
MiR-135a-5p suppresses trophoblast proliferative, migratory, invasive, and angiogenic activity in the context of unexplained spontaneous abortion.
Aberrant translation regulated by METTL1/WDR4-mediated tRNA N7-methylguanosine modification drives head and neck squamous cell carcinoma progression.
Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury.
p62 Promotes the Mitochondrial Localization of p53 through Its UBA Domain and Participates in Regulating the Sensitivity of Ovarian Cancer Cells to Cisplatin.
Iron metabolism protein transferrin receptor 1 involves in cervical cancer progression by affecting gene expression and alternative splicing in HeLa cells.
Effects of ALA-PDT on the macrophages in wound healing and its related mechanisms in vivo and in vitro.
Rutin-activated adipose tissue thermogenesis is correlated with increased intestinal short-chain fatty acid levels.
Dexmedetomidine attenuates perioperative neurocognitive disorders by suppressing hippocampal neuroinflammation and HMGB1/RAGE/NF-κB signaling pathway.
NPM1 promotes cell proliferation by targeting PRDX6 in colorectal cancer.
Deacetylation of Caveolin-1 by Sirt6 induces autophagy and retards high glucose-stimulated LDL transcytosis and atherosclerosis formation.
Heart-targeted amelioration of sepsis-induced myocardial dysfunction by microenvironment responsive nitric oxide nanogenerators in situ.
Sesamin Activates Skeletal Muscle FNDC5 Expression and Increases Irisin Secretion via the SIRT1 Signaling Pathway.
The mechanism of dioscin preventing lung cancer based on network pharmacology and experimental validation.
circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop.
Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached.
Transcriptome study digs out BMP2 involved in adipogenesis in sheep tails.
JNK and Jag1/Notch2 co-regulate CXCL16 to facilitate cypermethrin-induced kidney damage.
Difenoconazole causes spleen tissue damage and immune dysfunction of carp through oxidative stress and apoptosis.
Chronic exposure of alcohol triggers microglia-mediated synaptic elimination inducing cognitive impairment.
Lysyl oxidase-like 2 inhibitor rescues D-galactose-induced skeletal muscle fibrosis.
The neuroprotective effects of GPR55 against hippocampal neuroinflammation and impaired adult neurogenesis in CSDS mice.
Time series RNA-seq analysis identifies MAPK10 as a critical gene in diabetes mellitus-induced atrial fibrillation in mice.
Cortistatin attenuates titanium particle-induced osteolysis through regulation of TNFR1-ROS-caspase-3 signaling in osteoblasts.
Morphological and Proteomic Analyses of Soybean Seedling Interaction Mechanism Affected by Fiber Crosslinked with Zinc-Oxide Nanoparticles.
Discovery of Novel Phosphoinositide-3-Kinase α Inhibitors with High Selectivity, Excellent Bioavailability, and Long-Acting Efficacy for Gastric Cancer.
Dysregulation of SIRT3 SUMOylation Confers AML Chemoresistance via Controlling HES1-Dependent Fatty Acid Oxidation.
Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage.
Quantitative proteomics analysis to assess protein expression levels in the ovaries of pubescent goats.
Increased m6A-RNA methylation and FTO suppression is associated with myocardial inflammation and dysfunction during endotoxemia in mice.
BCAA-BCKA axis regulates WAT browning through acetylation of PRDM16.
Bioglass promotes wound healing by inhibiting endothelial cell pyroptosis through regulation of the connexin 43/reactive oxygen species (ROS) signaling pathway.
A homozygous loss-of-function mutation in FBXO43 causes human non-obstructive azoospermia.
CHMFL-BMX-078, a BMX inhibitor, overcomes the resistance of melanoma to vemurafenib via inhibiting AKT pathway.
An efficient strategy for digging protein-protein interactions for rational drug design - A case study with HIF-1α/VHL.
Qingwei San treats oral ulcer subjected to stomach heat syndrome in db/db mice by targeting TLR4/MyD88/NF-κB pathway.
ID2 inhibits innate antiviral immunity by blocking TBK1- and IKKε-induced activation of IRF3.
Increased expression of osteopontin in subchondral bone promotes bone turnover and remodeling, and accelerates the progression of OA in a mouse model.
The bibenzyl derivatives of Dendrobium officinale prevent UV-B irradiation induced photoaging via SIRT3.
Sodium hydrosulfide reverses β(2)-microglobulin-induced depressive-like behaviors of male Sprague-Dawley rats: Involving improvement of synaptic plasticity and enhancement of Warburg effect in hippocampus.
Nrf2 loss of function exacerbates endoplasmic reticulum stress-induced apoptosis in TBI mice.
Krill Oil Inhibits NLRP3 Inflammasome Activation in the Prevention of the Pathological Injuries of Diabetic Cardiomyopathy.
Amelioration of scopolamine-induced learning and memory impairment by the TRPV4 inhibitor HC067047 in ICR mice.
DsbA-L interacts with VDAC1 in mitochondrion-mediated tubular cell apoptosis and contributes to the progression of acute kidney disease.
Supervillin Contributes to LPS-induced Inflammatory Response in THP-1 Cell-derived Macrophages.
Chronic exposure to biomass ambient particulate matter triggers alveolar macrophage polarization and activation in the rat lung.
Dual effects of bisphenol A on wound healing, involvement of estrogen receptor β.
KDM2B overexpression prevents myocardial ischemia-reperfusion injury in rats through regulating inflammatory response via the TLR4/NF-κB p65 axis.
MxB inhibits long interspersed element type 1 retrotransposition.
Resveratrol attenuates inflammation and apoptosis through alleviating endoplasmic reticulum stress via Akt/mTOR pathway in fungus-induced allergic airways inflammation.
Vagus nerve stimulation alleviated cerebral ischemia and reperfusion injury in rats by inhibiting pyroptosis via α7 nicotinic acetylcholine receptor.
Toddalolactone protects against osteoarthritis by ameliorating chondrocyte inflammation and suppressing osteoclastogenesis.
RFC2: a prognosis biomarker correlated with the immune signature in diffuse lower-grade gliomas.
The expression of m6A enzymes in the hippocampus of diabetic cognitive impairment mice and the possible improvement of YTHDF1.
Inhibition of base editors with anti-deaminases derived from viruses.
FAEE exerts a protective effect against osteoporosis by regulating the MAPK signalling pathway.
Cdk5 Promotes Mitochondrial Fission via Drp1 Phosphorylation at S616 in Chronic Ethanol Exposure-Induced Cognitive Impairment.
Cellular communication network factor 1 interlinks autophagy and ERK signaling to promote osteogenesis of periodontal ligament stem cells.
The protective effects of Xuebijing injection on intestinal injuries of mice exposed to irradiation.
Defective autophagy triggered by arterial cyclic stretch promotes neointimal hyperplasia in vein grafts via the p62/nrf2/slc7a11 signaling pathway.
Attachment of -tBu groups to aza-BODIPY core at 3,5-sites with ultra-large Stokes shift to enhance photothermal therapy through apoptosis mechanism.
PVT1/miR-145-5p/HK2 modulates vascular smooth muscle cells phenotype switch via glycolysis: The new perspective on the spiral artery remodeling.
mmu-lncRNA 121686/hsa-lncRNA 520657 induced by METTL3 drive the progression of AKI by targeting miR-328-5p/HtrA3 signaling axis.
Proteomic-Based Approach Reveals the Involvement of Apolipoprotein A-I in Related Phenotypes of Autism Spectrum Disorder in the BTBR Mouse Model.
RNA-m6A modification of HDGF mediated by Mettl3 aggravates the progression of atherosclerosis by regulating macrophages polarization via energy metabolism reprogramming.
Effect of miR-143-3p from Extracellular Vesicles of Porcine Uterine Luminal Fluid on Porcine Trophoblast Cells.
Melatonin protects oocytes from cadmium exposure-induced meiosis defects by changing epigenetic modification and enhancing mitochondrial morphology in the mouse.
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
A synthetic pregnenolone analog promotes microtubule dynamics and neural development.
Hypoxia facilitates proliferation of smooth muscle cells derived from pluripotent stem cells for vascular tissue engineering.
ROS-responsive polymer nanoparticles with enhanced loading of dexamethasone effectively modulate the lung injury microenvironment.
Cypermethrin inhibits proliferation of Sertoli cells through AR involving DAB2IP/PI3K/AKT signaling pathway in vitro.
Effect of Silkworm Pupa Protein Hydrolysates on Proliferation of Gastric Cancer Cells In Vitro.
The Exocyst Is Required for CD36 Fatty Acid Translocase Trafficking and Free Fatty Acid Uptake in Skeletal Muscle Cells.
Chemical profile and miscarriage prevention evaluation of Jiao-Ai Decoction, a classical traditional Chinese formula.
Inhibition of BET Family Proteins Suppresses African Swine Fever Virus Infection.
The mechanism on Prevotella melaninogenica promoting the inflammatory progression of oral lichen planus.
Aperture Modulation of Isoreticular Metal Organic Frameworks for Targeted Antitumor Drug Delivery.
Quantitative proteomics and functional analysis identified novel targets for missed abortion.
Apextrin from Ruditapes philippinarum functions as pattern recognition receptor and modulates NF-κB pathway.
Cognitive enhancement and neuroprotective effects of OABL, a sesquiterpene lactone in 5xFAD Alzheimer's disease mice model.
O-GlcNAc transferase promotes the nuclear localization of the focal adhesion-associated protein Zyxin to regulate UV-induced cell death.
Protective Effects of Scutellarin on Acute Alcohol Intestinal Injury.
The lncRNA MIAT regulates CPT-1a mediated cardiac hypertrophy through m(6)A RNA methylation reading protein Ythdf2.
IL-37 isoform D acts as an inhibitor of soluble ST2 to boost type 2 immune homeostasis in white adipose tissue.
Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue.
The Tobacco β-Cembrenediol: A Prostate Cancer Recurrence Suppressor Lead and Prospective Scaffold via Modulation of Indoleamine 2,3-Dioxygenase and Tryptophan Dioxygenase.
The plant hormone abscisic acid stimulates megakaryocyte differentiation from human iPSCs in vitro.
Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.
ORP5 promotes tumor metastasis via stabilizing c-Met in renal cell carcinoma.
Age-related visual impairments and retinal ganglion cells axonal degeneration in a mouse model harboring OPTN (E50K) mutation.
Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma.
Bioinformatic Approach to Unveil Key Differentially Expressed Proteins in Human Sperm After Slow and Rapid Cryopreservation.
The Regulatory Role of GBF1 on Osteoclast Activation Through EIF2a Mediated ER Stress and Novel Marker FAM129A Induction.
Tributyltin Oxide Exposure During in vitro Maturation Disrupts Oocyte Maturation and Subsequent Embryonic Developmental Competence in Pigs.
Iron Overload-Induced Ferroptosis Impairs Porcine Oocyte Maturation and Subsequent Embryonic Developmental Competence in vitro.
The m(6)A Reader YTHDF1 Facilitates the Tumorigenesis and Metastasis of Gastric Cancer via USP14 Translation in an m(6)A-Dependent Manner.
Mechanically Activated Calcium Channel PIEZO1 Modulates Radiation-Induced Epithelial-Mesenchymal Transition by Forming a Positive Feedback With TGF-β1.
Expression and Functional Analysis of lncRNAs Involved in Platelet-Derived Growth Factor-BB-Induced Proliferation of Human Aortic Smooth Muscle Cells.
Transcriptome Differences in Pig Tracheal Epithelial Cells in Response to Pasteurella Multocida Infection.
DCI after Aneurysmal Subarachnoid Hemorrhage Is Related to the Expression of MFG-E8.
USP37 downregulation elevates the Chemical Sensitivity of Human Breast Cancer Cells to Adriamycin.
MnSOD Lysine 68 acetylation leads to cisplatin and doxorubicin resistance due to aberrant mitochondrial metabolism.
Rosuvastatin Nanomicelles Target Neuroinflammation and Improve Neurological Deficit in a Mouse Model of Intracerebral Hemorrhage.
GluN2A/ERK/CREB Signaling Pathway Involved in Electroacupuncture Regulating Hypothalamic-Pituitary-Adrenal Axis Hyperactivity.
Latent Sex Differences in CaMKII-nNOS Signaling That Underlie Antidepressant-Like Effects of Yueju-Ganmaidazao Decoction in the Hippocampus.
PADI6 Regulates Trophoblast Cell Migration-Invasion Through the Hippo/YAP1 Pathway in Hydatidiform Moles.
RNF128 suppresses the malignancy of colorectal cancer cells via inhibition of Wnt/β-catenin signaling.
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Ilexsaponin A(1) Ameliorates Diet-Induced Nonalcoholic Fatty Liver Disease by Regulating Bile Acid Metabolism in Mice.
Loss of Diacylglycerol Kinase α Enhances Macrophage Responsiveness.
ZnT8 Deficiency Protects From APAP-Induced Acute Liver Injury by Reducing Oxidative Stress Through Upregulating Hepatic Zinc and Metallothioneins.
The Downregulation of eIF3a Contributes to Vemurafenib Resistance in Melanoma by Activating ERK via PPP2R1B.
CXCL5 Downregulation in Villous Tissue Is Correlated With Recurrent Spontaneous Abortion.
Protective Effect of Remdesivir Against Pulmonary Fibrosis in Mice.
Chlorogenic Acid Ameliorates Damage Induced by Fluorene-9-Bisphenol in Porcine Sertoli Cells.
Human umbilical cord-derived mesenchymal stem cell therapy ameliorates lupus through increasing CD4+ T cell senescence via MiR-199a-5p/Sirt1/p53 axis.
circCDYL2, Overexpressed in Highly Migratory Colorectal Cancer Cells, Promotes Migration by Binding to Ezrin.
The Role of KDM2B and EZH2 in Regulating the Stemness in Colorectal Cancer Through the PI3K/AKT Pathway.
Expression and prognostic potential of PLEK2 in head and neck squamous cell carcinoma based on bioinformatics analysis.
Therapy of spinal cord injury by zinc modified gold nanoclusters via immune-suppressing strategies.
TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity.
Protocol for nuclear export signal characterization of cGAS in mammalian cells.
Yixin-Fumai granules improve sick sinus syndrome in aging mice through Nrf-2/HO-1 pathway: A new target for sick sinus syndrome.
MicroRNA‑8063 targets heterogeneous nuclear ribonucleoprotein AB to inhibit the self‑renewal of colorectal cancer stem cells via the Wnt/β‑catenin pathway.
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Cucurbit[7]uril as a Broad-Spectrum Antiviral Agent against Diverse RNA Viruses.
ZBP1-MLKL necroptotic signaling potentiates radiation-induced antitumor immunity via intratumoral STING pathway activation.
NORHA, a novel follicular atresia-related lncRNA, promotes porcine granulosa cell apoptosis via the miR-183-96-182 cluster and FoxO1 axis.
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Frugoside delays osteoarthritis progression via inhibiting miR-155-modulated synovial macrophage M1 polarization.
Naringin Promotes Skeletal Muscle Fiber Remodeling by the AdipoR1-APPL1-AMPK Signaling Pathway.
Comparative Proteomics of Rat Olfactory Bulb Reveal Insights into Susceptibility and Resiliency to Chronic-stress-induced Depression or Anxiety.
Arsenic trioxide induces expression of BCL-2 expression via NF-κB and p38 MAPK signaling pathways in BEAS-2B cells during apoptosis.
Reduced activity of intestinal surface Na(+)/H(+) exchanger NHE3 is a key factor for induction of diarrhea after PEDV infection in neonatal piglets.
Tripartite motif-containing protein 16 protects against myocardial ischemia/reperfusion injury by affecting the Keap1/Nrf2 axis.
EGFR and ERK activation resists flavonoid quercetin-induced anticancer activities in human cervical cancer cells in vitro.
Guaiazulene derivative 1,2,3,4-tetrahydroazuleno[1,2-b] tropone reduces the production of ATP by inhibiting electron transfer complex II.
Vagus nerve stimulation mediates microglia M1/2 polarization via inhibition of TLR4 pathway after ischemic stroke.
A network pharmacology approach to reveal the pharmacological targets and biological mechanism of compound kushen injection for treating pancreatic cancer based on WGCNA and in vitro experiment validation.
Inhibition of the NLRP3 inflammasome with MCC950 prevents chronic social isolation-induced depression-like behavior in male mice.
1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-κB/MAPK pathways.
Iptakalim alleviates synaptic damages via targeting mitochondrial ATP-sensitive potassium channel in depression.
Characterization of ALTO-encoding circular RNAs expressed by Merkel cell polyomavirus and trichodysplasia spinulosa polyomavirus.
Extracellular vesicles-based pre-targeting strategy enables multi-modal imaging of orthotopic colon cancer and image-guided surgery.
Functional domains and amino acid residues of Japanese eel IRF1, AjIRF1, regulate its nuclear import and IFN/Mx promoter activation.
Inhibition of ERAD synergizes with FTS to eradicate pancreatic cancer cells.
The combination of G-CSF and AMD3100 mobilizes bone marrow-derived stem cells to protect against cisplatin-induced acute kidney injury in mice.
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
lncRNA Ttc3-209 Promotes the Apoptosis of Retinal Ganglion Cells in Retinal Ischemia Reperfusion Injury by Targeting the miR-484/Wnt8a Axis.
Sesamin induces cell cycle arrest and apoptosis through p38/C-Jun N-terminal kinase mitogen-activated protein kinase pathways in human colorectal cancer cells.
Pharmacological effects of indole alkaloids from Alstonia scholaris (L.) R. Br. on pulmonary fibrosis in vivo.
Glycine alleviates fluoride-induced oxidative stress, apoptosis and senescence in a porcine testicular Sertoli cell line.
Alternative splicing transitions associate with emerging atrophy phenotype during denervation-induced skeletal muscle atrophy.
Melatonin ameliorates cypermethrin-induced impairments by regulating oxidative stress, DNA damage and apoptosis in porcine Sertoli cells.
Resolving the graft ischemia-reperfusion injury during liver transplantation at the single cell resolution.
Ameliorative effects of eosinophil deficiency on immune response, endoplasmic reticulum stress, apoptosis, and autophagy in fungus-induced allergic lung inflammation.
Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
PI3K/AKT pathway mediates the antidepressant- and anxiolytic-like roles of hydrogen sulfide in streptozotocin-induced diabetic rats via promoting hippocampal neurogenesis.
AEG-1 Knockdown Sensitizes Glioma Cells to Radiation Through Impairing Homologous Recombination Via Targeting RFC5.
The role of SAMM50 in non-alcoholic fatty liver disease: from genetics to mechanisms.
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking.
Theaflavin Promotes Mitochondrial Abundance and Glucose Absorption in Myotubes by Activating the CaMKK2-AMPK Signal Axis via Calcium-Ion Influx.
Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model.
Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB.
Attractin Gene Deficiency in Rats Leads to Impairments in Both Activity and Spatial Learning and Memory.
Betulinic acid attenuated bleomycin-induced pulmonary fibrosis by effectively intervening Wnt/β-catenin signaling.
ETV5 Regulates Hepatic Fatty Acid Metabolism Through PPAR Signaling Pathway.
Identification and Bioinformatic Assessment of circRNA Expression After RMI1 Knockdown and Ionizing Radiation Exposure.
NADPH levels affect cellular epigenetic state by inhibiting HDAC3-Ncor complex.
Libertellenone H, a Natural Pimarane Diterpenoid, Inhibits Thioredoxin System and Induces ROS-Mediated Apoptosis in Human Pancreatic Cancer Cells.
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.
A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA.
Formaldehyde induces ferroptosis in hippocampal neuronal cells by upregulation of the Warburg effect.
CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson's disease.
PDGF/MEK/ERK axis represses Ca(2+) clearance via decreasing the abundance of plasma membrane Ca(2+) pump PMCA4 in pulmonary arterial smooth muscle cells.
BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.
Oral Administration of Probiotic Bifidobacterium breve Improves Facilitation of Hippocampal Memory Extinction via Restoration of Aberrant Higher Induction of Neuropsin in an MPTP-Induced Mouse Model of Parkinson's Disease.
A novel tonicity-responsive microRNA miR-23a-5p modulates renal cell survival under osmotic stress through targeting heat shock protein 70 HSPA1B.
Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology.
Hypoxia-inducible factor-1α promotes proliferation of airway smooth muscle cells through miRNA-103-mediated signaling pathway under hypoxia.
Integrated Metabolomics and Transcriptomics Analyses Reveal Metabolic Landscape in Neuronal Cells during JEV Infection.
Decreased NHE3 activity in intestinal epithelial cells in TGEV and PEDV-induced piglet diarrhea.
The STING antagonist H-151 ameliorates psoriasis via suppression of STING/NF-κB-mediated inflammation.
Mbd2 deficiency alleviates retinal cell apoptosisvia the miR-345-5p/Atf1 axis in high glucoseinjury and streptozotocin-induced diabetic mice.
HRD1-mediated METTL14 degradation regulates m(6)A mRNA modification to suppress ER proteotoxic liver disease.
TRPV4 inhibitor HC067047 produces antidepressant-like effect in LPS-induced depression mouse model.
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
NOD2 deficiency confers a pro-tumorigenic macrophage phenotype to promote lung adenocarcinoma progression.
Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Ameliorate HaCaT Cell Photo-Aging.
Isoeucommin A attenuates kidney injury in diabetic nephropathy through the Nrf2/HO-1 pathway.
Cypermethrin induces Sertoli cell apoptosis through mitochondrial pathway associated with calcium.
TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.
The E2F1/USP11 positive feedback loop promotes hepatocellular carcinoma metastasis and inhibits autophagy by activating ERK/mTOR pathway.
High-Carbohydrate Diet Alleviates the Oxidative Stress, Inflammation and Apoptosis of Megalobrama amblycephala Following Dietary Exposure to Silver Nanoparticles.
Triptolide impairs glycolysis by suppressing GATA4/Sp1/PFKP signaling axis in mouse Sertoli cells.
KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathway.
HSP/HSC70 activity is required for Bombyx mori nucleopolyhedrovirus replication at the early infectious phase.
Salidroside Attenuates Doxorubicin-Induced Cardiac Dysfunction Partially Through Activation of QKI/FoxO1 Pathway.
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1.
Neural Tube Defects and ZIC4 Hypomethylation in Relation to Polycyclic Aromatic Hydrocarbon Exposure.
Identification of Transcriptional Variation in Aortic Remodeling Using a Murine Transverse Aortic Constriction (TAC) Model.
Similar Repair Effects of Human Placenta, Bone Marrow Mesenchymal Stem Cells, and Their Exosomes for Damaged SVOG Ovarian Granulosa Cells.
Beneficial Effects of Crocin against Depression via Pituitary Adenylate Cyclase-Activating Polypeptide.
Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway.
Skp2 modulates proliferation, senescence and tumorigenesis of glioma.
HCK can serve as novel prognostic biomarker and therapeutic target for Breast Cancer patients.
Repression of FGF signaling is responsible for Dnmt3b inhibition and impaired de novo DNA methylation during early development of in vitro fertilized embryos.
G Protein-Coupled Receptor 109A Maintains the Intestinal Integrity and Protects Against ETEC Mucosal Infection by Promoting IgA Secretion.
Integration of Transcriptomics and Metabolomics Reveals the Antitumor Mechanism Underlying Shikonin in Colon Cancer.
Possible Roles of Proinflammatory Signaling in Keratinocytes Through Aryl Hydrocarbon Receptor Ligands for the Development of Squamous Cell Carcinoma.
Cyclophilin A plays an important role in embryo implantation through activating Stat3.
Control the fate of human umbilical cord mesenchymal stem cells with dual-enzymatically cross-linked gelatin hydrogels for potential applications in nerve regeneration.
miR-361-5p Mediates SMAD4 to Promote Porcine Granulosa Cell Apoptosis through VEGFA.
Neddylation promotes protein translocation between the cytoplasm and nucleus.
EPS8 regulates an NLRP3 inflammasome-independent caspase-1 activation pathway in monosodium urate crystal-treated RAW264.7 macrophages.
RNA-binding protein CUGBP1 controls the differential INSR splicing in molecular subtypes of breast cancer cells and affects cell aggressiveness.
Chrysin Inhibits Melanoma Tumor Metastasis via Interfering with the FOXM1/β-Catenin Signaling.
Indole alkaloids from leaves of Alstonia scholaris (L.) R. Br. protect against emphysema in mice.
miR-203 inhibits cell proliferation and ERK pathway in prostate cancer by targeting IRS-1.
Identification of long-term survival-associated gene in breast cancer.
bta-miR-23a Regulates the Myogenic Differentiation of Fetal Bovine Skeletal Muscle-Derived Progenitor Cells by Targeting MDFIC Gene.
Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage.
Efficacy of a wound-dressing biomaterial on prevention of postinflammatory hyperpigmentation after suction blister epidermal grafting in stable vitiligo patients: a controlled assessor-blinded clinical study with in vitro bioactivity investigation.
The critical role of the hippocampal NLRP3 inflammasome in social isolation-induced cognitive impairment in male mice.
MitoQ attenuates brain damage by polarizing microglia towards the M2 phenotype through inhibition of the NLRP3 inflammasome after ICH.
The B7-H4 gene induces immune escape partly via upregulating the PD-1/Stat3 pathway in non-small cell lung cancer.
Protein target identification of ginsenosides in skeletal muscle tissues: discovery of natural small-molecule activators of muscle-type creatine kinase.
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Leptin mediates protection of hydrogen sulfide against 6-hydroxydopamine-induced Parkinson's disease: Involving enhancement in Warburg effect.
Neuropeptide Y1 receptor antagonist promotes osteoporosis and microdamage repair and enhances osteogenic differentiation of bone marrow stem cells via cAMP/PKA/CREB pathway.
A Novel Mechanism of bta-miR-210 in Bovine Early Intramuscular Adipogenesis.
Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep.
Synergistic antifibrotic effects of miR-451 with miR-185 partly by co-targeting EphB2 on hepatic stellate cells.
Synthesis and biological evaluations of N'-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents.
Mbd2 Mediates Retinal Cell Apoptosis by Targeting the lncRNA Mbd2-AL1/miR-188-3p/Traf3 Axis in Ischemia/Reperfusion Injury.
Anti-neuroinflammatory effect of 3,4-dihydroxybenzaldehyde in ischemic stroke.
Yueju-Ganmaidazao Decoction confers rapid antidepressant-like effects and the involvement of suppression of NMDA/NO/cGMP signaling.
The developmental and experience-dependent expression of IGF-2 in mice visual cortex.
Overexpression of NRF1-742 or NRF1-772 Reduces Arsenic-Induced Cytotoxicity and Apoptosis in Human HaCaT Keratinocytes.
Circular RNA hsa_circ_0008285 inhibits colorectal cancer cell proliferation and migration via the miR-382-5p/PTEN axis.
Hepatic HuR modulates lipid homeostasis in response to high-fat diet.
Melatonin regulates mitochondrial dynamics and alleviates neuron damage in prion diseases.
PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition.
A novel microRNA and its pfk target control growth length in the freshwater shrimp Neocaridina heteropoda.
Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5.
Nucleus-located PDK1 regulates growth, invasion and migration of breast cancer cells.
Autophagy inducer activates Nrf2-ARE pathway to attenuate aberrant alveolarization in neonatal rats with bronchopulmonary dysplasia.
PCNA and GSK3β interact with each other to regulate H1299 lung adenocarcinoma cells apoptosis.
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis.
SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1-STAT3 Signaling in Human ES Cells.
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA(2) phosphorylation in experimental ischemic stroke.
Pizotifen inhibits the proliferation and invasion of gastric cancer cells.
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABA(A) receptors.
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma.
NCAPG Dynamically Coordinates the Myogenesis of Fetal Bovine Tissue by Adjusting Chromatin Accessibility.
Sodium butyrate causes α-synuclein degradation by an Atg5-dependent and PI3K/Akt/mTOR-related autophagy pathway.
Oxidative stress-mediated hepatotoxicity in rats induced by ethanol extracts of different parts of Chloranthus serratus.
Regulation of indoleamine 2, 3-dioxygenase in hippocampal microglia by NLRP3 inflammasome in lipopolysaccharide-induced depressive-like behaviors.
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2.
Inhibition of p38 MAPK regulates epileptic severity by decreasing expression levels of A1R and ENT1.
Tongmai formula improves cardiac function via regulating mitochondrial quality control in the myocardium with ischemia/reperfusion injury.
Radiosensitization Effect of AGuIX, a Gadolinium-Based Nanoparticle, in Nonsmall Cell Lung Cancer.
Adiponectin protects HL-1 cardiomyocytes against rotenone-induced cytotoxicity through AMPK activation.
Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.
Blood coagulation factor VIII D1241E polymorphism leads to a weak malectin interaction and reduction of factor VIII posttranslational modification and secretion.
Homocysteine downregulates cardiac homeobox transcription factor NKX2.5 via IGFBP5.
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Interplay of m(6)A and H3K27 trimethylation restrains inflammation during bacterial infection.
WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy.
Myricetin ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting TGF-β signaling via targeting HSP90β.
Lnc-M2 controls M2 macrophage differentiation via the PKA/CREB pathway.
Anti-Inflammatory Effect of Simonsinol on Lipopolysaccharide Stimulated RAW264.7 Cells through Inactivation of NF-κB Signaling Pathway.
Precise base editing with CC context-specificity using engineered human APOBEC3G-nCas9 fusions.
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.
Design, synthesis and biological evaluation of a novel tubulin inhibitor SKLB0565 targeting the colchicine binding site.
Hypoxia induces tumor cell growth and angiogenesis in non-small cell lung carcinoma via the Akt-PDK1-HIF1α-YKL-40 pathway.
The E3 ubiquitin ligase Smurf2 regulates PARP1 stability to alleviate oxidative stress-induced injury in human umbilical vein endothelial cells.
Monophosphoryl lipid A alleviated radiation-induced testicular injury through TLR4-dependent exosomes.
Inhibition of histone acetyltransferase GCN5 extends lifespan in both yeast and human cell lines.
The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity.
Exogenous H(2)S Induces Hrd1 S-sulfhydration and Prevents CD36 Translocation via VAMP3 Ubiquitylation in Diabetic Hearts.
Systemic MCPIP1 deficiency in mice impairs lipid homeostasis.
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
BH3 mimetic ABT-263 enhances the anticancer effects of apigenin in tumor cells with activating EGFR mutation.
The Binding of PD-L1 and Akt Facilitates Glioma Cell Invasion Upon Starvation via Akt/Autophagy/F-Actin Signaling.
Neuroprotective Effect of Echinacoside in Subacute Mouse Model of Parkinson's Disease.
Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1).
(-)-Epigallocatechin-3-gallate derivatives combined with cisplatin exhibit synergistic inhibitory effects on non-small-cell lung cancer cells.
Long-Term Effects of Zinc Deficiency and Zinc Supplementation on Developmental Seizure-Induced Brain Damage and the Underlying GPR39/ZnT-3 and MBP Expression in the Hippocampus.
Catalpol prevents denervated muscular atrophy related to the inhibition of autophagy and reduces BAX/BCL2 ratio via mTOR pathway.
Lipoxin A4 Regulates Lipopolysaccharide-Induced BV2 Microglial Activation and Differentiation via the Notch Signaling Pathway.
Protein kinase C-iota-mediated glycolysis promotes non-small-cell lung cancer progression.
LXRα Promotes the Differentiation of Human Gastric Cancer Cells through Inactivation of Wnt/β-catenin Signaling.
A Comparative Peptidomic Characterization of Cultured Skeletal Muscle Tissues Derived From db/db Mice.
TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease.
An improved Tet-on system in microRNA overexpression and CRISPR/Cas9-mediated gene editing.
Anti-TGEV Miller Strain Infection Effect of Lactobacillus plantarum Supernatant Based on the JAK-STAT1 Signaling Pathway.
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Integrating yeast chemical genomics and mammalian cell pathway analysis.
Sorafenib kills liver cancer cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids via the ATP-AMPK-mTOR-SREBP1 signaling pathway.
The oncogenic role of CB2 in the progression of non-small-cell lung cancer.
Interactions between β-cyclodextrin and tea catechins, and potential anti-osteoclastogenesis activity of the (-)-epigallocatechin-3-gallate-β-cyclodextrin complex.
Exosomal transfer of miR-501 confers doxorubicin resistance and tumorigenesis via targeting of BLID in gastric cancer.
USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway.
Deregulated lncRNA expression profile in the mouse lung adenocarcinomas with KRAS-G12D mutation and P53 knockout.
Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and hippocampi of adolescent mice.
Oxidation derivative of (-)-epigallocatechin-3-gallate (EGCG) inhibits RANKL-induced osteoclastogenesis by suppressing RANK signaling pathways in RAW 264.7 cells.
HIF-1α contributes to Ang II-induced inflammatory cytokine production in podocytes.
The CRISPR-Cas13a Gene-Editing System Induces Collateral Cleavage of RNA in Glioma Cells.
An LTR retrotransposon-derived lncRNA interacts with RNF169 to promote homologous recombination.
Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury.
Astaxanthin inhibits proliferation and induces apoptosis of LX‑2 cells by regulating the miR‑29b/Bcl‑2 pathway.
Sirt2 epigenetically down-regulates PDGFRα expression and promotes CG4 cell differentiation.
Fuplatin: An Efficient and Low-Toxic Dual-Prodrug.
Casp8 hypomethylation and neural tube defects in association with polycyclic aromatic hydrocarbon exposure.
The protective effects of XH-105 against radiation-induced intestinal injury.
Leonurine promotes neurite outgrowth and neurotrophic activity by modulating the GR/SGK1 signaling pathway in cultured PC12 cells.
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Long noncoding RNA CCAT2 promotes hepatocellular carcinoma proliferation and metastasis through up-regulation of NDRG1.
Protective effect of hyperoside against renal ischemia-reperfusion injury via modulating mitochondrial fission, oxidative stress, and apoptosis.
Role of Nkx2.5 in H(2)O(2)-induced Nsd1 suppression.
Long-term pulmonary exposure to multi-walled carbon nanotubes promotes breast cancer metastatic cascades.
Aloperine suppresses human pulmonary vascular smooth muscle cell proliferation via inhibiting inflammatory response.
PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol Efflux.
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats.
YAP mediates the positive regulation of hnRNPK on the lung adenocarcinoma H1299 cell growth.
Involvement of the microglial NLRP3 inflammasome in the anti-inflammatory effect of the antidepressant clomipramine.
Resveratrol protects against isoproterenol induced myocardial infarction in rats through VEGF-B/AMPK/eNOS/NO signalling pathway.
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA(2) phosphorylation.
Matrix Metalloproteases-Mediated Cleavage on β-Dystroglycan May Play a Key Role in the Blood-Brain Barrier After Intracerebral Hemorrhage in Rats.
Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells.
KIAA1199 promotes metastasis of colorectal cancer cells via microtubule destabilization regulated by a PP2A/stathmin pathway.
Echinacoside protects against MPTP/MPP(+)-induced neurotoxicity via regulating autophagy pathway mediated by Sirt1.
Activation of brain endothelium by Escherichia coli K1 virulence factor cglD promotes polymorphonuclear leukocyte transendothelial migration.
Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates.
Structural and functional damage to the hippocampal neurovascular unit in diabetes-related depression.
Exosomes from human adipose-derived stem cells promote sciatic nerve regeneration via optimizing Schwann cell function.
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Water-separated part of Chloranthus serratus alleviates lipopolysaccharide- induced RAW264.7 cell injury mainly by regulating the MAPK and Nrf2/HO-1 inflammatory pathways.
Hypoxic postconditioning activates the Wnt/β-catenin pathway and protects against transient global cerebral ischemia through Dkk1 Inhibition and GSK-3β inactivation.
Inhibition of dendritic spine extension through acrolein conjugation with α-, β-tubulin proteins.
Overexpression of ANLN in lung adenocarcinoma is associated with metastasis.
Crocin induces anti-ischemia in middle cerebral artery occlusion rats and inhibits autophagy by regulating the mammalian target of rapamycin.
RMI1 contributes to DNA repair and to the tolerance to camptothecin.
EIF4A2 interacts with the membrane protein of transmissible gastroenteritis coronavirus and plays a role in virus replication.
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
NKX2-2 Suppresses Osteosarcoma Metastasis and Proliferation by Downregulating Multiple Target Genes.
Caffeine Promotes Conversion of Palmitic Acid to Palmitoleic Acid by Inducing Expression of fat-5 in Caenorhabditis elegans and scd1 in Mice.
EGFR as a Negative Regulatory Protein Adjusts the Activity and Mobility of NHE3 in the Cell Membrane of IPEC-J2 Cells With TGEV Infection.
Involvement of NMDA-AKT-mTOR Signaling in Rapid Antidepressant-Like Activity of Chaihu-jia-Longgu-Muli-tang on Olfactory Bulbectomized Mice.
Effect of Black Tea Extract and Thearubigins on Osteoporosis in Rats and Osteoclast Formation in vitro.
Phosphorylation of IRS4 by CK1γ2 promotes its degradation by CHIP through the ubiquitin/lysosome pathway.
Effect of decabrominated diphenyl ether exposure on spatial learning and memory, the expression and phosphorylation of hippocampal glutamate receptor subunits in adult Sprague-Dawley rats.
iTRAQ-Based Proteomics Analysis Reveals the Effect of Rhubarb in Rats with Ischemic Stroke.
The Protective Effect of New Compound XH-103 on Radiation-Induced GI Syndrome.
PAX2 may induce ADAM10 expression in renal tubular epithelial cells and contribute to epithelial-to-mesenchymal transition.
Rapid induction of apoptosis in tumor cells treated with a new platinum(II) complex based on amino-thiazolidinone.
Theabrownin suppresses in vitro osteoclastogenesis and prevents bone loss in ovariectomized rats.
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Apolipoprotein E deficiency accelerates atherosclerosis development in miniature pigs.
hnRNPK modulates selective quality-control autophagy by downregulating the expression of HDAC6 in 293 cells.
Temporal Proteomic Analysis of Pancreatic β-Cells in Response to Lipotoxicity and Glucolipotoxicity.
Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells.
Horizontal transfer of exosomal CXCR4 promotes murine hepatocarcinoma cell migration, invasion and lymphangiogenesis.
KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.
The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43.
PMN inhibits colorectal cancer cells through inducing mitotic arrest and p53-dependent apoptosis via the inhibition of tubulin polymerization.
Met is involved in TIGAR-regulated metastasis of non-small-cell lung cancer.
Combined treatment with Dendrobium candidum and black tea extract promotes osteoprotective activity in ovariectomized estrogen deficient rats and osteoclast formation.
CCAAT/enhancer-binding protein β overexpression alleviates myocardial remodelling by regulating angiotensin-converting enzyme-2 expression in diabetes.
[USP33 suppresses lung adenocarcinoma lung cell invasion and metastasis by down-regulating SLIT2/ROBO1 signaling pathway].
PTEN-L promotes type I interferon responses and antiviral immunity.
Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex.
Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production.
Synergistic neuroprotective effect of rasagiline and idebenone against retinal ischemia-reperfusion injury via the Lin28-let-7-Dicer pathway.
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
The antidepressant effects of ɑ-tocopherol are related to activation of autophagy via the AMPK/mTOR pathway.
Pu-erh Tea Extract Ameliorates Ovariectomy-Induced Osteoporosis in Rats and Suppresses Osteoclastogenesis In Vitro.
Role of the Ubiquitin C-Terminal Hydrolase L1-Modulated Ubiquitin Proteasome System in Auditory Cortex Senescence.
Neural Plasticity Associated with Hippocampal PKA-CREB and NMDA Signaling Is Involved in the Antidepressant Effect of Repeated Low Dose of Yueju Pill on Chronic Mouse Model of Learned Helplessness.
Tail Nerve Electrical Stimulation and Electro-Acupuncture Can Protect Spinal Motor Neurons and Alleviate Muscle Atrophy after Spinal Cord Transection in Rats.
Regulatory Axis of miR-195/497 and HMGA1-Id3 Governs Muscle Cell Proliferation and Differentiation.
2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G(2)/M cell cycle arrest through generation of thiol oxidative stress in human esophageal cancer cells.
Nrf2 Promotes Keratinocyte Proliferation in Psoriasis through Up-Regulation of Keratin 6, Keratin 16, and Keratin 17.
Synthesis of β-tubulin occurs within chromatoid body of round spermatids.
PRAS40 alleviates neurotoxic prion peptide-induced apoptosis via mTOR-AKT signaling.
High expression of ubiquitin-specific peptidase 39 is associated with the development of vascular remodeling.
Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages.
MicroRNA-17-92 Regulates the Transcription Factor E2F3b during Myogenesis In Vitro and In Vivo.
CBX3 promotes colon cancer cell proliferation by CDK6 kinase-independent function during cell cycle.
cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases.
ERK1/2-mediated Cytoplasmic Accumulation of hnRNPK Antagonizes TRAIL-induced Apoptosis through Upregulation of XIAP in H1299 Cells.
Abl2 kinase phosphorylates Bi-organellar regulator MNRR1 in mitochondria, stimulating respiration.
20-Hydroxyeicosatetraenoic acid regulates the expression of Nedd4‑2 in kidney and liver through a neddylation modification pathway.
miR-34b Modulates Skeletal Muscle Cell Proliferation and Differentiation.
Alginate enhances Toll-like receptor 4-mediated phagocytosis by murine RAW264.7 macrophages.
Knockdown of RMI1 impairs DNA repair under DNA replication stress.
Overexpression of DBC1, correlated with poor prognosis, is a potential therapeutic target for hepatocellular carcinoma.
LL-37-induced human mast cell activation through G protein-coupled receptor MrgX2.
The mechanically activated p38/MMP-2 signaling pathway promotes bone marrow mesenchymal stem cell migration in rats.
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
The DEAD-Box RNA Helicase DDX3 Interacts with NF-κB Subunit p65 and Suppresses p65-Mediated Transcription.
Six2 Is a Coordinator of LiCl-Induced Cell Proliferation and Apoptosis.
MicroRNA-378 Alleviates Cerebral Ischemic Injury by Negatively Regulating Apoptosis Executioner Caspase-3.
Up-regulation of miR-95-3p in hepatocellular carcinoma promotes tumorigenesis by targeting p21 expression.
Senkyunolide I attenuates oxygen-glucose deprivation/reoxygenation-induced inflammation in microglial cells.
Conventional protein kinase Cβ-mediated phosphorylation inhibits collapsin response-mediated protein 2 proteolysis and alleviates ischemic injury in cultured cortical neurons and ischemic stroke-induced mice.
The tumor suppressor PTEN has a critical role in antiviral innate immunity.
Hen egg white ovomacroglobulin promotes fibroblast migration via mediating cell adhesion and cytoskeleton.
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
Tubb3 regulation by the Erk and Akt signaling pathways: a mechanism involved in the effect of arginine ADP-ribosyltransferase 1 (Art1) on apoptosis of colon carcinoma CT26 cells.
Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers.
Inhibition of autophagy by 3-MA enhances IL-24-induced apoptosis in human oral squamous cell carcinoma cells.
Expression of Iodotyrosine Deiodinase in Thyroid and Other Organs in Iodine-Deficient and Iodine-Excess Rats.
Regulation of signal transducer and activator of transcription 3 and apoptotic pathways by betaine attenuates isoproterenol-induced acute myocardial injury in rats.
SCD1 negatively regulates autophagy-induced cell death in human hepatocellular carcinoma through inactivation of the AMPK signaling pathway.
Expression and localization of estrogen receptor in human breast cancer and its clinical significance.
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo.
Quantitative proteomic study of myocardial mitochondria in urea transporter B knockout mice.
The mechanisms of EGFR in the regulation of axon regeneration.
CXXC5 Associates with Smads to Mediate TNF-α Induced Apoptosis.
Downregulation of miR-181b in mouse brain following ischemic stroke induces neuroprotection against ischemic injury through targeting heat shock protein A5 and ubiquitin carboxyl-terminal hydrolase isozyme L1.
Modulation of calcineurin activity in mouse brain by chronic oral administration of cyclosporine A.
Effect of pioglitazone on altered expression of Aβ metabolism-associated molecules in the brain of fructose-drinking rats, a rodent model of insulin resistance.
Mutational analysis of ErbB2 intracellular localization.
Zhang L, Li Y, Wu Z, Shen Q, Zeng C, Liu H, Zhang X, Yang J, Liu Q, Tang D, Ou K, Fang Y
Frontiers in immunology 2024;15:1379586
Frontiers in immunology 2024;15:1379586
Xiasangju alleviate metabolic syndrome by enhancing noradrenaline biosynthesis and activating brown adipose tissue.
He C, An Y, Shi L, Huang Y, Zhang H, Fu W, Wang M, Shan Z, Du Y, Xie J, Huang Z, Sun W, Zhao Y, Zhao B
Frontiers in pharmacology 2024;15:1371929
Frontiers in pharmacology 2024;15:1371929
TRIM28 facilitates type I interferon activation by targeting TBK1.
Hua F, Nass T Jr, Parvatiyar K
Frontiers in immunology 2024;15:1279920
Frontiers in immunology 2024;15:1279920
Towards modelling tick-virus interactions using the weakly pathogenic Sindbis virus: Evidence that ticks are competent vectors.
Wang Y, Xu Z, Zhang H, Zhou Y, Cao J, Zhang Y, Wang Z, Zhou J
Frontiers in cellular and infection microbiology 2024;14:1334351
Frontiers in cellular and infection microbiology 2024;14:1334351
Matrix metalloproteinase-8 regulates dendritic cell tolerance in late polymicrobial sepsis via the nuclear factor kappa-B p65/β-catenin pathway.
Lu ZQ, Zhang C, Zhao LJ, Dong W, Lv L, Lu Y, Chen XY, Zhang J, Liu XY, Xiao Z, Chen LW, Yao YM, Zhao GJ
Burns & trauma 2024;12:tkad025
Burns & trauma 2024;12:tkad025
Global acetylome profiling indicates EPA impedes but OA promotes prostate cancer motility through altered acetylation of PFN1 and FLNA.
He C, Chen X, Chen Y, Sun J, Qi M, Rocha S, Wang M
Proteomics 2024 Oct;24(19):e2300393
Proteomics 2024 Oct;24(19):e2300393
Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation.
Delgado T, Emerson J, Hong M, Keillor JW, Johnson GV
bioRxiv : the preprint server for biology 2024 Oct 31;
bioRxiv : the preprint server for biology 2024 Oct 31;
Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation.
Delgado T, Emerson J, Hong M, Keillor JW, Johnson GV
bioRxiv : the preprint server for biology 2024 Nov 11;
bioRxiv : the preprint server for biology 2024 Nov 11;
Itaconate inhibits corticosterone-induced necroptosis and neuroinflammation via up-regulating menin in HT22 cells.
Liang JY, Gao S, Jiang JM, Zhang P, Zou W, Tang XQ, Tang YY
Journal of physiology and biochemistry 2024 May;80(2):393-405
Journal of physiology and biochemistry 2024 May;80(2):393-405
PMP2 regulates myelin thickening and ATP production during remyelination.
Hong J, Garfolo R, Kabre S, Humml C, Velanac V, Roué C, Beck B, Jeanette H, Haslam S, Bach M, Arora S, Acheta J, Nave KA, Schwab MH, Jourd'heuil D, Poitelon Y, Belin S
Glia 2024 May;72(5):885-898
Glia 2024 May;72(5):885-898
ER-tethered RNA-binding protein controls NADPH oxidase translation for hydrogen peroxide homeostasis.
Pei X, Wang Z, He W, Li S, Chen X, Fan Z, Lan Y, Yuan L, Xu P
Redox biology 2024 May;71:103126
Redox biology 2024 May;71:103126
EMX2 inhibits clear cell renal cell carcinoma progress via modulating Akt/FOXO3a pathway.
Zhou X, Dong S, Zhou Y, He Z, Zhang Z, Liao L, Zou B, Zheng X, Peng K, Duan X
Molecular carcinogenesis 2024 May;63(5):951-961
Molecular carcinogenesis 2024 May;63(5):951-961
PLCE1 enhances mitochondrial dysfunction to promote GSDME-mediated pyroptosis in doxorubicin-induced cardiotoxicity.
Tuersuntuoheti M, Peng F, Li J, Zhou L, Gao H, Gong H
Biochemical pharmacology 2024 May;223:116142
Biochemical pharmacology 2024 May;223:116142
Prevotella melaninogenica disrupted oral epithelial barrier function via myosin light chain kinase.
Guo Y, Han W, He Y
Oral diseases 2024 May 8;
Oral diseases 2024 May 8;
D-mannose alleviates intervertebral disc degeneration through glutamine metabolism.
Dong ZL, Jiao X, Wang ZG, Yuan K, Yang YQ, Wang Y, Li YT, Wang TC, Kan TY, Wang J, Tao HR
Military Medical Research 2024 May 6;11(1):28
Military Medical Research 2024 May 6;11(1):28
PD-1/PD-L1 axis is involved in the interaction between microglial polarization and glioma.
Wang XP, Guo W, Chen YF, Hong C, Ji J, Zhang XY, Dong YF, Sun XL
International immunopharmacology 2024 May 30;133:112074
International immunopharmacology 2024 May 30;133:112074
Transcriptomics confirms IRF1 as a key regulator of pyroptosis in diabetic retinopathy.
Xian Y, Wang X, Yu Y, Chen X
Biochemical and biophysical research communications 2024 May 21;709:149760
Biochemical and biophysical research communications 2024 May 21;709:149760
Targeted degradation of oncogenic BCR-ABL by silencing the gene of NEDD8 E3 ligase RAPSYN.
Sun Y, Wang Y, Liu C, Huang Y, Long Q, Ju C, Zhang C, Chen Y
Journal of nanobiotechnology 2024 May 13;22(1):247
Journal of nanobiotechnology 2024 May 13;22(1):247
Esculin suppresses the PERK-eIF2α-CHOP pathway by enhancing SIRT1 expression in oxidative stress-induced rat chondrocytes, mitigating osteoarthritis progression in a rat model.
Cheng Z, Liu Z, Liu C, Yang A, Miao H, Bai X
International immunopharmacology 2024 May 10;132:112061
International immunopharmacology 2024 May 10;132:112061
The disrupting effect of chlormequat chloride on growth hormone is associated with pregnancy.
Wu Z, Ma L, Su D, Xiagedeer B
Toxicology letters 2024 May 1;395:17-25
Toxicology letters 2024 May 1;395:17-25
Crocin Inhibits Orbital Fibroblasts Fibrosis in Thyroid-Associated Ophthalmopathy.
Xu S, Mao H
Current eye research 2024 Mar;49(3):330-337
Current eye research 2024 Mar;49(3):330-337
SESN1 functions as a new tumor suppressor gene via Toll-like receptor signaling pathway in neuroblastoma.
Hua Z, Chen B, Gong B, Lin M, Ma Y, Li Z
CNS neuroscience & therapeutics 2024 Mar;30(3):e14664
CNS neuroscience & therapeutics 2024 Mar;30(3):e14664
OTUD7B knockdown inhibits the proliferation and stemness of breast cancer cells by destabilizing FOXM1.
Wang H, Han S, Xiao J, Fu X, Chen W, Zhuo D
Oncology letters 2024 Mar;27(3):102
Oncology letters 2024 Mar;27(3):102
ACOX1 deficiency-induced lipid metabolic disorder facilitates chronic interstitial fibrosis development in renal allografts.
Zhang YH, Bin Liu, Meng Q, Zhang D, Yang H, Li G, Wang Y, Liu M, Liu N, Yu J, Liu S, Zhou H, Xu ZX, Wang Y
Pharmacological research 2024 Mar;201:107105
Pharmacological research 2024 Mar;201:107105
RSK4 promotes the macrophage recruitment and M2 polarization in esophageal squamous cell carcinoma.
He S, Lu M, Zhang L, Wang Z
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166996
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166996
Enhanced glutathione production protects against zearalenone-induced oxidative stress and ferroptosis in female reproductive system.
Fu W, Dai C, Ma Z, Li Q, Lan D, Sun C, Wu X, Li J, Wang S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Mar;185:114462
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Mar;185:114462
DTTZ suppresses ferroptosis and reverses mitochondrial dysfunction in normal tissues affected by chemotherapy.
Yang Y, Chen Y, Tang H, Zhang Z, Zhou X, Xu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116227
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116227
Genome-wide analyses reveal the regulatory roles of DNA methylation-regulated alternative promoter transcripts in breast cancer.
Song Y, Shen T, Sun H, Wang X
Human genetics 2024 Mar;143(3):385-399
Human genetics 2024 Mar;143(3):385-399
The RNA m(6)A reader IGF2BP3 regulates NFAT1/IRF1 axis-mediated anti-tumor activity in gastric cancer.
Ge L, Rui Y, Wang C, Wu Y, Wang H, Wang J
Cell death & disease 2024 Mar 6;15(3):192
Cell death & disease 2024 Mar 6;15(3):192
Pan-cancer integrated analysis of ANKRD1 expression, prognostic value, and potential implications in cancer.
Xu X, Zhong D, Wang X, Luo F, Zheng X, Feng T, Chen R, Cheng Y, Wang Y, Ma G
Scientific reports 2024 Mar 4;14(1):5268
Scientific reports 2024 Mar 4;14(1):5268
RFX1 regulates foam cell formation and atherosclerosis by mediating CD36 expression.
Yang S, Min X, Hu L, Zheng M, Lu S, Zhao M, Jia S
International immunopharmacology 2024 Mar 30;130:111751
International immunopharmacology 2024 Mar 30;130:111751
Discovery and verification of mmu_Circ_26986/hsa_Circ_0072463 as a potential biomarker and intervention target for sepsis-associated acute kidney injury.
Peng X, Li H, Zhang W, Zhang D
Cellular and molecular life sciences : CMLS 2024 Mar 28;81(1):154
Cellular and molecular life sciences : CMLS 2024 Mar 28;81(1):154
Securin acetylation prevents precocious separase activation and premature sister chromatid separation.
Wang T, Zou Y, Meng H, Zheng P, Teng J, Huang N, Chen J
Current biology : CB 2024 Mar 25;34(6):1295-1308.e5
Current biology : CB 2024 Mar 25;34(6):1295-1308.e5
Piperine promotes PI3K/AKT/mTOR-mediated gut-brain autophagy to degrade α-Synuclein in Parkinson's disease rats.
Yu L, Hu X, Xu R, Zhao Y, Xiong L, Ai J, Wang X, Chen X, Ba Y, Xing Z, Guo C, Mi S, Wu X
Journal of ethnopharmacology 2024 Mar 25;322:117628
Journal of ethnopharmacology 2024 Mar 25;322:117628
An intranasal influenza virus vector vaccine protects against Helicobacter pylori in mice.
Nie L, Huang Y, Cheng Z, Luo H, Zhan Y, Dou K, Ma C, Yu C, Luo C, Liu Z, Liu S, Zhu Y
Journal of virology 2024 Mar 19;98(3):e0192323
Journal of virology 2024 Mar 19;98(3):e0192323
Metformin switches cell death modes to soothe the apical periodontitis via ZBP1.
Liu H, Liu YX, Fan W, Fan B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23549
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23549
YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia.
Liu Z, Li S, Chen S, Sheng J, Li Z, Lv T, Yu W, Fan Y, Wang J, Liu W, Hu S, Jin J
iScience 2024 Mar 15;27(3):109125
iScience 2024 Mar 15;27(3):109125
Design, synthesis, and bioactivity evaluation of novel indole-selenide derivatives as P-glycoprotein inhibitors against multi-drug resistance in MCF-7/ADR cell.
Yang Z, Luo D, Shao C, Hu H, Yang X, Cai Y, Mou X, Wu Q, Xu H, Sun X, Wang H, Hou W
European journal of medicinal chemistry 2024 Mar 15;268:116207
European journal of medicinal chemistry 2024 Mar 15;268:116207
Purinergic P2X7 receptor involves in anti-retinal photodamage effects of berberine.
Ye SS, Wang JN, Zhao YF, Dai LS, Zhang JZ, Zuo YQ, Song JT
Purinergic signalling 2024 Mar 15;
Purinergic signalling 2024 Mar 15;
Antidepressant fluoxetine alleviates colitis by reshaping intestinal microenvironment.
Teng S, Yang Y, Zhang W, Li X, Li W, Cui Z, Min L, Wu J
Cell communication and signaling : CCS 2024 Mar 12;22(1):176
Cell communication and signaling : CCS 2024 Mar 12;22(1):176
Mefloquine enhances the efficacy of anti-PD-1 immunotherapy via IFN-γ-STAT1-IRF1-LPCAT3-induced ferroptosis in tumors.
Tao Q, Liu N, Wu J, Chen J, Chen X, Peng C
Journal for immunotherapy of cancer 2024 Mar 11;12(3)
Journal for immunotherapy of cancer 2024 Mar 11;12(3)
Electroacupuncture regulates the P2X(7)R-NLRP3 inflammatory cascade to relieve decreased sensation on ocular surface of type 2 diabetic rats with dry eye.
Wan MM, Fu ZY, Jin T, Wang ZY, Sun XY, Gao WP
Purinergic signalling 2024 Mar 11;
Purinergic signalling 2024 Mar 11;
IL-35 ameliorates lipopolysaccharide-induced endothelial dysfunction by inhibiting endothelial-to-mesenchymal transition.
Feng J, Li K, Xie F, Han L, Wu Y
International immunopharmacology 2024 Mar 10;129:111567
International immunopharmacology 2024 Mar 10;129:111567
The mechanism of EGFL7 regulating neovascularization in diabetic retinopathy through the PI3K/AKT/VEGFA pathway.
Xian Y, Wang X, Yu Y, Chen X
Life sciences 2024 Mar 1;340:122483
Life sciences 2024 Mar 1;340:122483
Arecoline induces neurotoxicity in HT22 cells via the promotion of endoplasmic reticulum stress and downregulation of the Nrf2/HO-1 pathway.
Yan H, Ding J, Li X, Li S, Zhang D
Environmental toxicology 2024 Jun;39(6):3410-3424
Environmental toxicology 2024 Jun;39(6):3410-3424
LUC7L3 is a downstream factor of SRSF1 and prevents genomic instability.
Zhang X, Guo J, Shi X, Zhou X, Chen Q
Cell insight 2024 Jun;3(3):100170
Cell insight 2024 Jun;3(3):100170
Conditional deficiency of Rho-associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice.
Akamine T, Terabayashi T, Sasaki T, Hayashi R, Abe I, Hirayama F, Nureki SI, Ikawa M, Miyata H, Tokunaga A, Kobayashi T, Hanada K, Thumkeo D, Narumiya S, Ishizaki T
FEBS open bio 2024 Jun;14(6):906-921
FEBS open bio 2024 Jun;14(6):906-921
Bu-Shen-Ning-Xin decoction inhibits macrophage activation to ameliorate premature ovarian insufficiency-related osteoimmune disorder via FSH/FSHR pathway.
Sun H, Qi Q, Pan X, Zhou J, Wang J, Li L, Li D, Wang L
Drug discoveries & therapeutics 2024 Jun 6;18(2):106-116
Drug discoveries & therapeutics 2024 Jun 6;18(2):106-116
A pan-KRAS degrader for the treatment of KRAS-mutant cancers.
Yang J, Wang QL, Wang GN, Ye JC, Li ZQ, Wang JY, Liang ZH, Li SX, Sun C, Liao WT, Gao YJ, Wang J, Mao Y, Yu C, Feng GK, Zeng MS
Cell discovery 2024 Jun 28;10(1):70
Cell discovery 2024 Jun 28;10(1):70
Frataxin deficiency shifts metabolism to promote reactive microglia via glucose catabolism.
Sciarretta F, Zaccaria F, Ninni A, Ceci V, Turchi R, Apolloni S, Milani M, Della Valle I, Tiberi M, Chiurchiù V, D'Ambrosi N, Pedretti S, Mitro N, Volontè C, Amadio S, Aquilano K, Lettieri-Barbato D
Life science alliance 2024 Jul;7(7)
Life science alliance 2024 Jul;7(7)
Transformation of A1/A2 Astrocytes Participates in Brain Ischemic Tolerance Induced by Cerebral Ischemic Preconditioning via Inhibiting NDRG2.
Liu XH, Zhang LY, Liu XY, Zhang JG, Hu YY, Zhao CG, Xian XH, Li WB, Zhang M
Neurochemical research 2024 Jul;49(7):1665-1676
Neurochemical research 2024 Jul;49(7):1665-1676
Quercetin prevented diabetic nephropathy by inhibiting renal tubular epithelial cell apoptosis via the PI3K/AKT pathway.
Liu F, Feng Q, Yang M, Yang Y, Nie J, Wang S
Phytotherapy research : PTR 2024 Jul;38(7):3594-3606
Phytotherapy research : PTR 2024 Jul;38(7):3594-3606
PC (16:0/14:0) ameliorates hyperoxia-induced bronchopulmonary dysplasia by upregulating claudin-1 and promoting alveolar type II cell repair.
Hou W, Yu B, Li Y, Yan X, Su Q, Fang X, Zhou X, Yu Z
The international journal of biochemistry & cell biology 2024 Jul;172:106587
The international journal of biochemistry & cell biology 2024 Jul;172:106587
Preventive effect of propolis on cognitive decline in Alzheimer's disease model mice.
Inagaki R, Yamakuni T, Saito T, Saido TC, Moriguchi S
Neurobiology of aging 2024 Jul;139:20-29
Neurobiology of aging 2024 Jul;139:20-29
Genome-scale exon perturbation screens uncover exons critical for cell fitness.
Xiao MS, Damodaran AP, Kumari B, Dickson E, Xing K, On TA, Parab N, King HE, Perez AR, Guiblet WM, Duncan G, Che A, Chari R, Andresson T, Vidigal JA, Weatheritt RJ, Aregger M, Gonatopoulos-Pournatzis T
Molecular cell 2024 Jul 11;84(13):2553-2572.e19
Molecular cell 2024 Jul 11;84(13):2553-2572.e19
Circular RNA circXPO1 Promotes Multiple Myeloma Progression by Regulating miR-495-3p/DNA Damage-Induced Transcription 4 Axis.
Li F, Liu J, Miao J, Hong F, Liu R, Lv Y, Yang Y, He A, Wang J
DNA and cell biology 2024 Jan;43(1):39-55
DNA and cell biology 2024 Jan;43(1):39-55
Aristolochic acid I aggravates oxidative stress-mediated apoptosis by inhibiting APE1/Nrf2/HO-1 signaling.
Zhang Q, Tian L, Hu Y, Jiang W, Wang X, Chen L, Cheng S, Ying J, Jiang B, Zhang L
Toxicology mechanisms and methods 2024 Jan;34(1):20-31
Toxicology mechanisms and methods 2024 Jan;34(1):20-31
HSP90β regulates EAAT2 expression and participates in ischemia‑reperfusion injury in rats.
Liang T, Hu X, Zeng L, Zhou Z, Zhang J, Xu Z, Zeng J, Xu P
Molecular medicine reports 2024 Jan;29(1)
Molecular medicine reports 2024 Jan;29(1)
Ailanthone synergizes with PARP1 inhibitor in tumour growth inhibition through crosstalk of DNA repair pathways in gastric cancer.
Wang C, Yi T, Li X, Cui J, Li B, Qin Y, Tang S, Zhang J
Journal of cellular and molecular medicine 2024 Jan;28(2):e18033
Journal of cellular and molecular medicine 2024 Jan;28(2):e18033
Identification of potential miR‑155 target genes in epidermal immune microenvironment of atopic dermatitis patients and their inflammatory effects on HaCaT cells.
Wang X, Chen L, Chen X, Liu C, Qiu W, Guo K
Experimental and therapeutic medicine 2024 Jan;27(1):25
Experimental and therapeutic medicine 2024 Jan;27(1):25
MicroRNA-124 conducts neuroprotective effect via inhibiting AK4/ATF3 after subarachnoid hemorrhage.
Jiang W, Jia Q, Ma H, Han S, Bi S, Zhu K, Chen L, Liang G
Experimental brain research 2024 Jan;242(1):33-45
Experimental brain research 2024 Jan;242(1):33-45
Hydrogen sulfide attenuates depression-like behaviours in Parkinson's disease model rats by improving synaptic plasticity in a hippocampal Warburg effect-dependent manner.
Liu F, Tian Q, Tang HL, Cheng X, Zou W, Zhang P
Pharmacology, biochemistry, and behavior 2024 Jan;234:173677
Pharmacology, biochemistry, and behavior 2024 Jan;234:173677
Amyloid pathology reduces ELP3 expression and tRNA modifications leading to impaired proteostasis.
Pereira M, Ribeiro DR, Berg M, Tsai AP, Dong C, Nho K, Kaiser S, Moutinho M, Soares AR
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166857
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166857
Inulin alters gut microbiota to alleviate post-stroke depressive-like behavior associated with the IGF-1-mediated MAPK signaling pathway.
Shao R, Tan X, Pan M, Huang J, Huang L, Bi B, Huang X, Wang J, Li X
Brain and behavior 2024 Jan;14(1):e3387
Brain and behavior 2024 Jan;14(1):e3387
Lycopene protects against ionizing radiation-induced testicular damage by inhibition of apoptosis and mitochondrial dysfunction.
Qu M, He Q, Guo B
Food science & nutrition 2024 Jan;12(1):534-546
Food science & nutrition 2024 Jan;12(1):534-546
Mitochondria-derived peptide is an effective target for treating streptozotocin induced painful diabetic neuropathy through induction of activated protein kinase/peroxisome proliferator-activated receptor gamma coactivator 1alpha -mediated mitochondrial biogenesis.
Xu L, Tang X, Yang L, Chang M, Xu Y, Chen Q, Lu C, Liu S, Jiang J
Molecular pain 2024 Jan-Dec;20:17448069241252654
Molecular pain 2024 Jan-Dec;20:17448069241252654
TBC1D1 represses glioma progression by altering the integrity of the cytoskeleton.
Cai J, Jiang Y, Chen P, Liang J, Zhang Y, Yuan R, Fan H, Zhong Y, Cai J, Cheng S, Zhang Y
Aging 2024 Jan 5;16(1):431-444
Aging 2024 Jan 5;16(1):431-444
α-Synuclein reduces acetylserotonin O-methyltransferase mediated melatonin biosynthesis by microtubule-associated protein 1 light chain 3 beta-related degradation pathway.
Jia C, Tian L, Cheng C, Zhang J, Al-Nusaif M, Li T, Yang H, Lin Y, Li S, Le W
Cellular and molecular life sciences : CMLS 2024 Jan 27;81(1):61
Cellular and molecular life sciences : CMLS 2024 Jan 27;81(1):61
FBXO28 promotes cell proliferation, migration and invasion via upregulation of the TGF-beta1/SMAD2/3 signaling pathway in ovarian cancer.
Song G, Sun Z, Chu M, Zhang Z, Chen J, Wang Z, Zhu X
BMC cancer 2024 Jan 24;24(1):122
BMC cancer 2024 Jan 24;24(1):122
DDX60 Promotes Migration and Invasion of Head and Neck Squamous Cell Carcinoma Cell through the NF-κB/IFI27 Signaling Pathway.
Han Y, Gao J, Liu L
Frontiers in bioscience (Landmark edition) 2024 Jan 17;29(1):14
Frontiers in bioscience (Landmark edition) 2024 Jan 17;29(1):14
Discovery of (quinazolin-6-yl)benzamide derivatives containing a 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety as potent reversal agents against P-glycoprotein-mediated multidrug resistance.
Xue WH, Liu KL, Zhang TJ, Dong G, Wang JH, Wang J, Guo S, Hu J, Zhang QY, Li XY, Meng FH
European journal of medicinal chemistry 2024 Jan 15;264:116039
European journal of medicinal chemistry 2024 Jan 15;264:116039
Preliminary study on the role of the CSMD2 gene in bladder cancer.
Yao Z, Yang H, Liu X, Jiang M, Deng W, Fu B
Heliyon 2024 Jan 15;10(1):e22593
Heliyon 2024 Jan 15;10(1):e22593
GDF11 mediates H(2)S to prevent chronic stress-induced cognitive impairment by reducing hippocampal NLRP3/caspase-1-dependent pyroptosis.
Wang B, Chen SM, Yang SQ, Jiang JM, Zhang P, Zou W, Tang XQ
Journal of affective disorders 2024 Jan 1;344:600-611
Journal of affective disorders 2024 Jan 1;344:600-611
Mechanism of synergistic inhibitory effect of benzyl isothiocyanate and zoledronic acid combination on breast cancer induction of osteoclast differentiation.
Hahm ER, Kim SH, Pore SK, Mathan SV, Singh RP, Singh SV
Molecular carcinogenesis 2024 Feb;63(2):301-313
Molecular carcinogenesis 2024 Feb;63(2):301-313
Aucubin provides protection against cerebral ischaemia-reperfusion injury by suppressing neuronal apoptosis, oxidative stress, and inflammation through the modulation of the AKT-GSK-3β-Nrf2 signal cascade.
Yang F, Lian Q, Zhang X, Sun F, Jia S, Zhao W
Toxicology and applied pharmacology 2024 Feb;483:116829
Toxicology and applied pharmacology 2024 Feb;483:116829
Circular RNA RHBDD1 regulates tumorigenicity and ferroptosis in colorectal cancer by mediating the ELAVL1/SCD mRNA interaction.
Long F, Zhong C, Long Q, Zhu K, Wang J, Yu Y, Xie C, Hu G
Cancer gene therapy 2024 Feb;31(2):237-249
Cancer gene therapy 2024 Feb;31(2):237-249
Single-cell multi-omics profiling of human preimplantation embryos identifies cytoskeletal defects during embryonic arrest.
Wang T, Peng J, Fan J, Tang N, Hua R, Zhou X, Wang Z, Wang L, Bai Y, Quan X, Wang Z, Zhang L, Luo C, Zhang W, Kang X, Liu J, Li L, Li L
Nature cell biology 2024 Feb;26(2):263-277
Nature cell biology 2024 Feb;26(2):263-277
CDC123 promotes Hepatocellular Carcinoma malignant progression by regulating CDKAL1.
Wang Y, Pan H, Gong X, Wang Z, Qin X, Zhou S, Zhu C, Hu X, Chen S, Liu H, Jin H, Pang Q, Wu W
Pathology, research and practice 2024 Feb;254:154987
Pathology, research and practice 2024 Feb;254:154987
A prognostic model based on Scissor(+) cancer associated fibroblasts identified from bulk and single cell RNA sequencing data in head and neck squamous cell carcinoma.
Tian G, Zhang J, Bao Y, Li Q, Hou J
Cellular signalling 2024 Feb;114:110984
Cellular signalling 2024 Feb;114:110984
Discovery of PRDM16-Mediated TRPA1 Induction as the Mechanism for Low Tubulo-Interstitial Fibrosis in Diabetic Kidney Disease.
Xu F, Jiang H, Li X, Pan J, Li H, Wang L, Zhang P, Chen J, Qiu S, Xie Y, Li Y, Zhang D, Dong Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2306704
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2306704
CEBPA Overexpression Enhances β-Cell Proliferation and Survival.
Ellsworth PN, Herring JA, Leifer AH, Ray JD, Elison WS, Poulson PD, Crabtree JE, Van Ry PM, Tessem JS
Biology 2024 Feb 9;13(2)
Biology 2024 Feb 9;13(2)
Warm Acupuncture Reduces Pain and Inflammation in Rats with Lumbar Disc Herniation Induced by Autologous Nucleus Pulposus Transplantation via Regulating p38MAPK/NF-κB Pathway.
Pan F, Zeng F, Chen Y, Zheng Y, Chen Z, Zhu X, Yin MF, Huang Y, Liu Z
Journal of acupuncture and meridian studies 2024 Feb 29;17(1):28-37
Journal of acupuncture and meridian studies 2024 Feb 29;17(1):28-37
Identification of hypoxia- and immune-related biomarkers in patients with ischemic stroke.
Zhang H, Sun J, Zou P, Huang Y, Yang Q, Zhang Z, Luo P, Jiang X
Heliyon 2024 Feb 29;10(4):e25866
Heliyon 2024 Feb 29;10(4):e25866
Specific inhibition of TET1 in the spinal dorsal horn alleviates inflammatory pain in mice by regulating synaptic plasticity.
Yang K, Wei R, Liu Q, Tao Y, Wu Z, Yang L, Wang QH, Wang H, Pan Z
Neuropharmacology 2024 Feb 15;244:109799
Neuropharmacology 2024 Feb 15;244:109799
Electroacupuncture stimulation ameliorates cognitive impairment induced by long-term high-fat diet by regulating microglial BDNF.
Yang X, Yu Z, An L, Jing X, Yuan M, Xu T, Yu Z, Xu B, Lu M
Brain research 2024 Feb 15;1825:148710
Brain research 2024 Feb 15;1825:148710
MiR-145-5p overexpression rejuvenates aged adipose stem cells and accelerates wound healing.
Li C, Ren S, Xiong H, Chen J, Jiang T, Guo J, Yan C, Chen Z, Yang X, Xu X
Biology open 2024 Feb 15;13(2)
Biology open 2024 Feb 15;13(2)
Calcitonin gene-related peptide attenuated discogenic low back pain in rats possibly via inhibiting microglia activation.
Xie W, Li F, Han Y, Chi X, Qin Y, Ye F, Li Z, Xiao J
Heliyon 2024 Feb 15;10(3):e25906
Heliyon 2024 Feb 15;10(3):e25906
M2 macrophages promote subconjunctival fibrosis through YAP/TAZ signalling.
Wang Y, Geng X, Guo Z, Chu D, Liu R, Cheng B, Cui H, Li C, Li J, Li Z
Annals of medicine 2024 Dec;56(1):2313680
Annals of medicine 2024 Dec;56(1):2313680
Nervous necrosis virus induced vacuolization is a Rab5- and actin-dependent process.
Liu J, Wang L, Zhang X, Wang S, Qin Q
Virulence 2024 Dec;15(1):2301244
Virulence 2024 Dec;15(1):2301244
A ROS-responsive and scavenging hydrogel for postoperative abdominal adhesion prevention.
Zhang T, Huang Y, Gong Y, Shi X, Xiao D, Ren L, Dai X, Zeng Z, Zhao C
Acta biomaterialia 2024 Aug;184:98-113
Acta biomaterialia 2024 Aug;184:98-113
Silencing lncRNA-DARS-AS1 suppresses nonsmall cell lung cancer progression by stimulating miR-302a-3p to inhibit ACAT1 expression.
Li J, Li Y, Sun X, Wei L, Guan J, Fu L, Du J, Zhang X, Cheng M, Ma H, Jiang S, Zheng Q, Wang L
Molecular carcinogenesis 2024 Apr;63(4):757-771
Molecular carcinogenesis 2024 Apr;63(4):757-771
CRISPR/Cas9 based gene editing of Frizzled class receptor 6 (FZD6) reveals its role in depressive symptoms through disrupting Wnt/β-catenin signaling pathway.
Han H, Xu M, Wang J, Li MD, Yang Z
Journal of advanced research 2024 Apr;58:129-138
Journal of advanced research 2024 Apr;58:129-138
Mechanism of acupuncture in attenuating cerebral ischaemia-reperfusion injury based on nuclear receptor coactivator 4 mediated ferritinophagy.
Xinchang Z, Zheng H, Peiyan H, Mengning Y, Zhihui Z, Guangxia NI
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Apr;44(2):345-352
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Apr;44(2):345-352
Icariin alleviates renal inflammation and tubulointerstitial fibrosis via Nrf2-mediated attenuation of mitochondrial damage.
Ding N, Sun S, Zhou S, Lv Z, Wang R
Cell biochemistry and function 2024 Apr;42(3):e4005
Cell biochemistry and function 2024 Apr;42(3):e4005
Citric acid promotes SPARC release in pancreatic cancer cells and inhibits the progression of pancreatic tumors in mice on a high-fat diet.
Xiao G, Wei Y, Xie R, Tsang Y, Gu J, Shen D, Ding M, Yuan J, Xu D, Fei J
The FEBS journal 2024 Apr;291(8):1699-1718
The FEBS journal 2024 Apr;291(8):1699-1718
A novel and ubiquitous miRNA-involved regulatory module ensures precise phosphorylation of RNA polymerase II and proper transcription.
Wang Z, Zhong S, Zhang S, Zhang B, Zheng Y, Sun Y, Zhang Q, Liu X
PLoS pathogens 2024 Apr;20(4):e1012138
PLoS pathogens 2024 Apr;20(4):e1012138
Clock knockout in inhibitory neurons reduces predisposition to epilepsy and influences anxiety-like behaviors in mice.
Deng L, Jiang H, Lin J, Xu D, Qi A, Guo Q, Li PP, Wang X, Liu JS, Fu X, Li P
Neurobiology of disease 2024 Apr;193:106457
Neurobiology of disease 2024 Apr;193:106457
Human amniotic mesenchymal stromal cell-derived exosomes promote neuronal function by inhibiting excessive apoptosis in a hypoxia/ischemia-induced cerebral palsy model: A preclinical study.
Zhou Y, He LN, Wang LN, Chen KY, Qian SD, Li XH, Zang J, Wang DM, Yu XF, Gao J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116321
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116321
HSPA4 upregulation induces immune evasion via ALKBH5/CD58 axis in gastric cancer.
Suo D, Gao X, Chen Q, Zeng T, Zhan J, Li G, Zheng Y, Zhu S, Yun J, Guan XY, Li Y
Journal of experimental & clinical cancer research : CR 2024 Apr 8;43(1):106
Journal of experimental & clinical cancer research : CR 2024 Apr 8;43(1):106
Short-term regulation of TSFM level does not alter amyloidogenesis and mitochondrial function in type-specific cells.
Li XY, Zhou GF, Xie XY, Pu YL, -Chen X, Li CL, Yang J, Wang L, Chen GJ
Molecular biology reports 2024 Apr 5;51(1):484
Molecular biology reports 2024 Apr 5;51(1):484
Identification of ferroptosis related genes and pathways in prostate cancer cells under erastin exposure.
Wu F, Huang F, Jiang N, Su J, Yao S, Liang B, Li W, Yan T, Zhou S, Zhou Q
BMC urology 2024 Apr 4;24(1):78
BMC urology 2024 Apr 4;24(1):78
Static magnetic field-induced IL-6 secretion in periodontal ligament stem cells accelerates orthodontic tooth movement.
Luo S, Li Z, Liu L, Zhao J, Ge W, Zhang K, Zhou Z, Liu Y
Scientific reports 2024 Apr 29;14(1):9851
Scientific reports 2024 Apr 29;14(1):9851
The role of FPR2-mediated ferroptosis in formyl peptide-induced acute lung injury against endothelial barrier damage and protective effect of the mitochondria-derived peptide MOTS-c.
Wen Z, Fan J, Zhan F, Li X, Li B, Lu P, Yao X, Shen Z, Liu Z, Wang C, Li X, Jin W, Zhang X, Qi Y, Wang X, Song M
International immunopharmacology 2024 Apr 20;131:111911
International immunopharmacology 2024 Apr 20;131:111911
PEI, a new transfection method, augments the inhibitory effect of RBM5 on prostate cancer.
Zhou X, Cao Y, Li R, Di X, Wang Y, Wang K
Biochemical and biophysical research communications 2024 Apr 16;704:149703
Biochemical and biophysical research communications 2024 Apr 16;704:149703
Phosphoglycerate mutase 5 exacerbates liver ischemia-reperfusion injury by activating mitochondrial fission.
Tang H, Yu Q, Chen X, Zhang J, Guo D, Guo W, Zhang S, Shi X
Scientific reports 2024 Apr 12;14(1):8535
Scientific reports 2024 Apr 12;14(1):8535
Germline USP36 Mutation Confers Resistance to EGFR-TKIs by Upregulating MLLT3 Expression in Patients with Non-Small Cell Lung Cancer.
Guan S, Chen X, Wei Y, Wang F, Xie W, Chen Y, Liang H, Zhu X, Yang Y, Fang W, Huang Y, Zhao H, Zhang X, Liu S, Zhuang W, Huang M, Wang X, Zhang L
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Apr 1;30(7):1382-1396
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Apr 1;30(7):1382-1396
Penfluroidol Attenuates the Imbalance of the Inflammatory Response by Repressing the Activation of the NLRP3 Inflammasome and Reduces Oxidative Stress via the Nrf2/HO-1 Signaling Pathway in LPS-Induced Macrophages.
Li Q, Wu L, Cheng B, Tao S, Wang W, Luo Z, Fan J
Mediators of inflammation 2023;2023:9940858
Mediators of inflammation 2023;2023:9940858
S100 Calcium Binding Protein A16 Promotes Cell Proliferation by triggering LATS1 ubiquitin degradation mediated by CUL4A ligase to inhibit Hippo pathway in Glioma development.
Hu Y, Zhang R, Lu S, Zhang W, Wang D, Ge Y, Jiang F, Qin X, Liu Y
International journal of biological sciences 2023;19(7):2034-2052
International journal of biological sciences 2023;19(7):2034-2052
XPOT Disruption Suppresses TNBC Growth through Inhibition of Specific tRNA Nuclear Exportation and TTC19 Expression to Induce Cytokinesis Failure.
Dai H, Yang X, Sheng X, Wang Y, Zhang S, Zhang X, Hu L, Zhang Z, Dong X, Yin W, Yao L, Lu J
International journal of biological sciences 2023;19(16):5319-5336
International journal of biological sciences 2023;19(16):5319-5336
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
Zhu Y, Sun W, Jiang X, Bai R, Luo Y, Gao Y, Li S, Huang Z, Gong Y, Xie C
PloS one 2023;18(1):e0281132
PloS one 2023;18(1):e0281132
Sodium Butyrate Ameliorates Type 2 Diabetes-Related Sarcopenia Through IL-33-Independent ILC2s/IL-13/STAT3 Signaling Pathway.
Cao Y, Li Y, Han W, Jia X, Zhu P, Wei B, Cong X, Wang Z
Journal of inflammation research 2023;16:343-358
Journal of inflammation research 2023;16:343-358
Electroacupuncture alleviates perioperative hypothalamus-pituitary-adrenal axis dysfunction via circRNA-miRNA-mRNA networks.
Wang Y, Hu W, Han J, Zheng J, Jiang N, Feng Y, Tian Z
Frontiers in molecular neuroscience 2023;16:1115569
Frontiers in molecular neuroscience 2023;16:1115569
Prognostic values of Annexins and validation of the influence on cell proliferation, migration, and invasion in uveal melanoma.
Zhao A, Wang Z, Wang Y, Chen X
American journal of translational research 2023;15(5):3131-3151
American journal of translational research 2023;15(5):3131-3151
HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication.
Yuan S, Xu J, Wang M, Huang J, Ma S, Liu Y, Ke Y, Zeng X, Wu K, Wang J, Tian X, Zheng D, Yousaf T, Naz W, Sun J, Chen L, Guo D, Guo M, Sun G
Cellular and molecular gastroenterology and hepatology 2023;15(1):179-195
Cellular and molecular gastroenterology and hepatology 2023;15(1):179-195
Neutrophil infiltration associated genes on the prognosis and tumor immune microenvironment of lung adenocarcinoma.
Liu R, Zhu G, Sun Y, Li M, Hu Z, Cao P, Li X, Song Z, Chen J
Frontiers in immunology 2023;14:1304529
Frontiers in immunology 2023;14:1304529
Porcine epidemic diarrhea virus causes diarrhea by activating EGFR to regulates NHE3 activity and mobility on plasma membrane.
Zhang Y, Zhang S, Sun Z, Liu X, Liao G, Niu Z, Kan Z, Xu S, Zhang J, Zou H, Zhang X, Song Z
Frontiers in microbiology 2023;14:1237913
Frontiers in microbiology 2023;14:1237913
Weight bearing training alleviates muscle atrophy and pyroptosis of middle-aged rats.
Fu P, Gong L, Yang L, Tang S, Ma F
Frontiers in endocrinology 2023;14:1202686
Frontiers in endocrinology 2023;14:1202686
The overexpression of actin related protein 2/3 complex subunit 1B(ARPC1B) promotes the ovarian cancer progression via activation of the Wnt/β-catenin signaling pathway.
Huang J, Zhou H, Tan C, Mo S, Liu T, Kuang Y
Frontiers in immunology 2023;14:1182677
Frontiers in immunology 2023;14:1182677
Selenomethionine against titanium particle-induced osteolysis by regulating the ROS-dependent NLRP3 inflammasome activation via the β-catenin signaling pathway.
Yu R, Yuan Y, Liu Z, Liu L, Xu Z, Zhao Y, Jia C, Zhang P, Li H, Liu Y, Wang Y, Li W, Nie L, Sun X, Li Y, Liu B, Liu H
Frontiers in immunology 2023;14:1171150
Frontiers in immunology 2023;14:1171150
Pan-cancer analysis of Krüppel-like factor 3 and its carcinogenesis in pancreatic cancer.
Zhu J, Teng H, Zhu X, Yuan J, Zhang Q, Zou Y
Frontiers in immunology 2023;14:1167018
Frontiers in immunology 2023;14:1167018
Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis via the p38/p53/p21 pathway.
Xiong D, Gao F, Shao J, Pan Y, Wang S, Wei D, Ye S, Chen Y, Chen R, Yue B, Li J, Chen J
Frontiers in pharmacology 2023;14:1141800
Frontiers in pharmacology 2023;14:1141800
Application of a JEG-3 organoid model to study HLA-G function in the trophoblast.
Zhuang BM, Cao DD, Liu XF, Wang L, Lin XL, Duan YG, Lee CL, Chiu PCN, Yeung WSB, Yao YQ
Frontiers in immunology 2023;14:1130308
Frontiers in immunology 2023;14:1130308
Grouper cGAS is a negative regulator of STING-mediated interferon response.
Zhang L, Zhang X, Liao J, Xu L, Kang S, Chen H, Sun M, Wu S, Xu Z, Wei S, Qin Q, Wei J
Frontiers in immunology 2023;14:1092824
Frontiers in immunology 2023;14:1092824
Tsp-1(+) microglia attenuate retinal neovascularization by maintaining the expression of Smad3 in endothelial cells through exosomes with decreased miR-27a-5p.
Luo Q, Jiang Z, Jiang J, Wan L, Li Y, Huang Y, Qiu J, Yu K, Zhuang J
Theranostics 2023;13(11):3689-3706
Theranostics 2023;13(11):3689-3706
Targeting plasmodium α-tubulin-1 to block malaria transmission to mosquitoes.
Zhang G, Niu G, Hooker-Romera D, Shabani S, Ramelow J, Wang X, Butler NS, James AA, Li J
Frontiers in cellular and infection microbiology 2023;13:1132647
Frontiers in cellular and infection microbiology 2023;13:1132647
Inhibition of Hypothalamic FTO Activates STAT3 Signal through ERK1/2 Associated with Reductions in Food Intake and Body Weight.
Hu F, Yan HJ, Gao CX, Sun WW, Long YS
Neuroendocrinology 2023;113(1):80-91
Neuroendocrinology 2023;113(1):80-91
Combined effects of EMP and RF field on emotional behavior in mice.
Qin T, Liu L, Wang X, Guo L, Lin J, Du J, Xue Y, Lai P, Jing Y, Ding G
Frontiers in public health 2023;11:1087161
Frontiers in public health 2023;11:1087161
The protective role of EP300 in monocrotaline-induced pulmonary hypertension.
Yang L, Tian J, Wang J, Zeng J, Wang T, Lin B, Linneman J, Li L, Niu Y, Gou D, Zhang Y
Frontiers in cardiovascular medicine 2023;10:1037217
Frontiers in cardiovascular medicine 2023;10:1037217
Effect of renal denervation on cardiac remodelling and function in rats with chronic intermittent hypoxia.
Lu D, Wang K, Jiang W, Zhang H, Zhang H
Clinical and experimental pharmacology & physiology 2023 Sep;50(9):719-727
Clinical and experimental pharmacology & physiology 2023 Sep;50(9):719-727
Aβ Induces Neuroinflammation and Microglial M1 Polarization via cGAS-STING-IFITM3 Signaling Pathway in BV-2 Cells.
Wu Z, Tang W, Ibrahim FEEM, Chen X, Yan H, Tao C, Wang Z, Guo Y, Fu Y, Wang Q, Ge Y
Neurochemical research 2023 Sep;48(9):2881-2894
Neurochemical research 2023 Sep;48(9):2881-2894
DELE1 oligomerization promotes integrated stress response activation.
Yang J, Baron KR, Pride DE, Schneemann A, Guo X, Chen W, Song AS, Aviles G, Kampmann M, Wiseman RL, Lander GC
Nature structural & molecular biology 2023 Sep;30(9):1295-1302
Nature structural & molecular biology 2023 Sep;30(9):1295-1302
STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1(+) NK cells.
Lu L, Yang C, Zhou X, Wu L, Hong X, Li W, Wang X, Yang Y, Cao D, Zhang A, Di W, Deng L
Cell reports 2023 Sep 26;42(9):113108
Cell reports 2023 Sep 26;42(9):113108
Optineurin tunes outside-in signaling to regulate lysosome biogenesis and phagocytic clearance in the retina.
Tan LX, Germer CJ, Thamban T, La Cunza N, Lakkaraju A
Current biology : CB 2023 Sep 25;33(18):3805-3820.e7
Current biology : CB 2023 Sep 25;33(18):3805-3820.e7
Steroidal saponins PPI/CCRIS/PSV induce cell death in pancreatic cancer cell through GSDME-dependent pyroptosis.
Liu Y, Zhang W, Zhou H, Chen J
Biochemical and biophysical research communications 2023 Sep 17;673:51-58
Biochemical and biophysical research communications 2023 Sep 17;673:51-58
MicroRNA miR-223 modulates NLRP3 and Keap1, mitigating lipopolysaccharide-induced inflammation and oxidative stress in bovine mammary epithelial cells and murine mammary glands.
Zhou M, Barkema HW, Gao J, Yang J, Wang Y, Kastelic JP, Khan S, Liu G, Han B
Veterinary research 2023 Sep 14;54(1):78
Veterinary research 2023 Sep 14;54(1):78
EP300 promotes ferroptosis via HSPA5 acetylation in pancreatic cancer.
Wang Y, Liu Y, Wang C, Kang R, Tang D, Liu J
Scientific reports 2023 Sep 11;13(1):15004
Scientific reports 2023 Sep 11;13(1):15004
Upregulation of HDAC9 in hippocampal neurons mediates depression-like behaviours by inhibiting ANXA2 degradation.
Dai Y, Wei T, Huang Y, Bei Y, Lin H, Shen Z, Yu L, Yang M, Xu H, He W, Lin Z, Dai H
Cellular and molecular life sciences : CMLS 2023 Sep 10;80(10):289
Cellular and molecular life sciences : CMLS 2023 Sep 10;80(10):289
FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer.
Wang D, Wu S, He J, Sun L, Zhu H, Zhang Y, Liu S, Duan X, Wang Y, Xu T
Journal of experimental & clinical cancer research : CR 2023 Sep 1;42(1):222
Journal of experimental & clinical cancer research : CR 2023 Sep 1;42(1):222
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production.
Yao X, Liu H, Wang Z, Lu F, Chen W, Feng Q, Miao Y, Zhang J, Wang Y, Chen Y, Xue L, Liu Y, Chen L, Zhang Q
Oncogene 2023 Oct;42(43):3206-3218
Oncogene 2023 Oct;42(43):3206-3218
Antigenic variation in hemagglutinin-neuraminidase of Newcastle disease virus isolated from Tibet, China.
Chang Z, Dong X, Guan Z, Lu K, Chen X, Wei X, Guo H, Dang R, Wang J, Wang X, Xiao S, Yang Z, Liu H
Veterinary microbiology 2023 Oct;285:109872
Veterinary microbiology 2023 Oct;285:109872
Glycogen synthase kinase 3 controls T-cell exhaustion by regulating NFAT activation.
Fu Y, Wang J, Liu C, Liao K, Gao X, Tang R, Fan B, Hong Y, Xiao N, Xiao C, Liu WH
Cellular & molecular immunology 2023 Oct;20(10):1127-1139
Cellular & molecular immunology 2023 Oct;20(10):1127-1139
CALHM2 V136G polymorphism reduces astrocytic ATP release and is associated with depressive symptoms and Alzheimer's disease risk.
Liao Y, Wang Y, Tao QQ, Yang C, Wang J, Cheng J, Ma J, Wu ZY, Pan RY, Yuan Z
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Oct;19(10):4407-4420
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Oct;19(10):4407-4420
Acetyl-coenzyme A acetyltransferase 1 promotes brown adipogenesis by activating the AMPK-PGC1α signaling pathway.
Zhu K, Ni L, Han J, Yan Z, Zhang Y, Wang F, Wang L, Yang X
Biochimica et biophysica acta. Molecular and cell biology of lipids 2023 Oct;1868(10):159369
Biochimica et biophysica acta. Molecular and cell biology of lipids 2023 Oct;1868(10):159369
A high-throughput Gaussia luciferase reporter assay for screening potential gasdermin E activators against pancreatic cancer.
Liu Y, Zhang X, Zhang P, He T, Zhang W, Ma D, Li P, Chen J
Acta pharmaceutica Sinica. B 2023 Oct;13(10):4253-4272
Acta pharmaceutica Sinica. B 2023 Oct;13(10):4253-4272
Plasma exosomes induce inflammatory immune response in patients with acute myocardial infarction.
Gong Z, Wen M, Zhang W, Yu L, Huang C, Xu Y, Xia Z, Xu M, Xu J, Liang Q, Bao H, Cheng X
Archives of physiology and biochemistry 2023 Oct;129(5):1168-1176
Archives of physiology and biochemistry 2023 Oct;129(5):1168-1176
Dihydromyricetin confers cerebroprotection against subarachnoid hemorrhage via the Nrf2-dependent Prx2 signaling cascade.
Li XJ, Pang C, Peng Z, Zhuang Z, Lu Y, Li W, Zhang HS, Zhang XS, Hang CH
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:154997
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:154997
Elucidating the pharmacological effects of Compound Kushen injection on MYC-P15-CCND1 signaling pathway in nasopharyngeal carcinoma - An in vitro study.
Wu Z, Wu C, Shi J, Huang Z, Lu S, Tan Y, You R, Hai L, Huang J, Guo S, Gao Y, Jin Z, Tao X, You L, Wu J
Journal of ethnopharmacology 2023 Oct 28;315:116702
Journal of ethnopharmacology 2023 Oct 28;315:116702
Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.
Wang M, Tang J, Zhang S, Pang K, Zhao Y, Liu N, Huang J, Kang J, Dong S, Li H, Tian Z, Duan B, Lu F, Zhang W
Cell death discovery 2023 Oct 24;9(1):394
Cell death discovery 2023 Oct 24;9(1):394
Identification and development of Tetra-ARMS PCR-based screening test for a genetic variant of OLA1 (Tyr254Cys) in the human failing heart.
Dubey PK, Dubey S, Singh S, Bhat PD, Pogwizd S, Krishnamurthy P
medRxiv : the preprint server for health sciences 2023 Oct 19;
medRxiv : the preprint server for health sciences 2023 Oct 19;
Suppression of the gut microbiota-bile acid-FGF19 axis in patients with atrial fibrillation.
Zuo K, Fang C, Gao Y, Fu Y, Wang H, Li J, Zhong J, Yang X, Xu L
Cell proliferation 2023 Nov;56(11):e13488
Cell proliferation 2023 Nov;56(11):e13488
GPR37 promotes colorectal cancer liver metastases by enhancing the glycolysis and histone lactylation via Hippo pathway.
Zhou J, Xu W, Wu Y, Wang M, Zhang N, Wang L, Feng Y, Zhang T, Wang L, Mao A
Oncogene 2023 Nov;42(45):3319-3330
Oncogene 2023 Nov;42(45):3319-3330
C-IGF1R encoded by cIGF1R acts as a molecular switch to restrict mitophagy of drug-tolerant persister tumour cells in non-small cell lung cancer.
Wang H, Liang Y, Zhang T, Yu X, Song X, Chen Y, Mao Q, Xia W, Chen B, Xu L, Dong G, Jiang F
Cell death and differentiation 2023 Nov;30(11):2365-2381
Cell death and differentiation 2023 Nov;30(11):2365-2381
Inhibition of ANXA2 activity attenuates epileptic susceptibility and GluA1 phosphorylation.
Ma L, Wu Q, Yuan J, Wang Y, Zhang P, Liu Q, Tan D, Liang M, Chen Y
CNS neuroscience & therapeutics 2023 Nov;29(11):3644-3656
CNS neuroscience & therapeutics 2023 Nov;29(11):3644-3656
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
Yuan Z, Li J, Zou X, Liu C, Lu J, Ni C, Tang L, Wu X, Yan F
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
Mulberry leaf flavonoids activate BAT and induce browning of WAT to improve type 2 diabetes via regulating the AMPK/SIRT1/PGC-1α signaling pathway.
Cheng L, Shi L, He C, Wang C, Lv Y, Li H, An Y, Duan Y, Dai H, Zhang H, Huang Y, Fu W, Sun W, Zhao B
Chinese journal of natural medicines 2023 Nov;21(11):812-829
Chinese journal of natural medicines 2023 Nov;21(11):812-829
Co-delivery of azithromycin and ibuprofen by ROS-responsive polymer nanoparticles synergistically attenuates the acute lung injury.
Muhammad W, Zhang Y, Zhu J, Xie J, Wang S, Wang R, Feng B, Zhou J, Chen W, Xu Y, Yao Q, Yu Y, Cao H, Gao C
Biomaterials advances 2023 Nov;154:213621
Biomaterials advances 2023 Nov;154:213621
FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation.
Tian T, Xie X, Yi W, Zhou Y, Xu Y, Wang Z, Zhang J, Lin M, Zhang R, Lv Z, Li X, Lv L, Xu Y
Cell reports 2023 Nov 28;42(11):113362
Cell reports 2023 Nov 28;42(11):113362
Lnc-PTCHD4-AS inhibits gastric cancer through MSH2-MSH6 dimerization and ATM-p53-p21 activation.
Wang J, Mi Y, Sun X, Xue X, Zhao H, Zhang M, Hu B, Bukhari I, Zheng P
Aging 2023 Nov 27;15(22):13558-13578
Aging 2023 Nov 27;15(22):13558-13578
PDK4 rescues high-glucose-induced senescent fibroblasts and promotes diabetic wound healing through enhancing glycolysis and regulating YAP and JNK pathway.
Ma Z, Ding Y, Ding X, Mou H, Mo R, Tan Q
Cell death discovery 2023 Nov 25;9(1):424
Cell death discovery 2023 Nov 25;9(1):424
PHD3 inhibits colon cancer cell metastasis through the occludin-p38 pathway.
Li Y, Yuan T, Zhang H, Liu S, Lun J, Guo J, Wang Y, Zhang Y, Fang J
Acta biochimica et biophysica Sinica 2023 Nov 25;55(11):1749-1757
Acta biochimica et biophysica Sinica 2023 Nov 25;55(11):1749-1757
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
Cheng Z, Wang H, Yang Z, Li J, Chen X
BMC cancer 2023 Nov 20;23(1):1128
BMC cancer 2023 Nov 20;23(1):1128
Screening UFMylation-associated genes in heart tissues of Ufm1-transgenic mice.
Jiajia H, Ziyao Y, Jiaqi Z, Yanli C, Xiaotao Z, Ming S
BMC cardiovascular disorders 2023 Nov 18;23(1):567
BMC cardiovascular disorders 2023 Nov 18;23(1):567
Dopamine and cyclic adenosine monophosphate-regulated phosphoprotein with an apparent Mr of 32000 promotes colorectal cancer growth.
He K, Xie CZ, Li Y, Chen ZZ, Xu SH, Huang SQ, Yang JG, Wei ZQ, Peng XD
World journal of gastrointestinal oncology 2023 Nov 15;15(11):1936-1950
World journal of gastrointestinal oncology 2023 Nov 15;15(11):1936-1950
Gastrodia elata specific miRNA attenuates neuroinflammation via modulating NF-κB signaling pathway.
Fu J, Lu ZT, Wu G, Yang ZC, Wu X, Wang D, Nie ZM, Sheng Q
The International journal of neuroscience 2023 Nov 15;:1-11
The International journal of neuroscience 2023 Nov 15;:1-11
Lnc AC016727.1/BACH1/HIF-1 α signal loop promotes the progression of non-small cell lung cancer.
Zhang L, Liang J, Qin H, Lv Y, Liu X, Li Z, Chao Z, Jia C, Qin X, Zhang H
Journal of experimental & clinical cancer research : CR 2023 Nov 10;42(1):296
Journal of experimental & clinical cancer research : CR 2023 Nov 10;42(1):296
Activation of LXRα attenuates 2-Ethylhexyl diphenyl phosphate (EHDPP) induced placental dysfunction.
Zhang Y, Liang J, Gu H, Du T, Xu P, Yu T, He Q, Huang Z, Lei S, Li J
Ecotoxicology and environmental safety 2023 Nov 1;266:115605
Ecotoxicology and environmental safety 2023 Nov 1;266:115605
Sevoflurane induces neurotoxic effects on developing neurons through the WNK1/NKCC1/Ca(2+) /Drp-1 signalling pathway.
Bai YF, Li WJ, Ji YW, An LX, Zhang L, Li JF
Clinical and experimental pharmacology & physiology 2023 May;50(5):393-402
Clinical and experimental pharmacology & physiology 2023 May;50(5):393-402
Discovery of a natural small-molecule AMP-activated kinase activator that alleviates nonalcoholic steatohepatitis.
Chen J, Xu L, Zhang XQ, Liu X, Zhang ZX, Zhu QM, Liu JY, Iqbal MO, Ding N, Shao CL, Wei MY, Gu YC
Marine life science & technology 2023 May;5(2):196-210
Marine life science & technology 2023 May;5(2):196-210
PGC-1α Affects Epileptic Seizures by Regulating Mitochondrial Fusion in Epileptic Rats.
Li D, Zhang L, Tuo J, Zhang F, Tai Z, Liu X, Qiu X, Zhang H, Yang J, Wang J, Luo Z, Xu Z
Neurochemical research 2023 May;48(5):1361-1369
Neurochemical research 2023 May;48(5):1361-1369
PDLIM3 supports hedgehog signaling in medulloblastoma by facilitating cilia formation.
Zhang J, Yang Y, Li X, Li G, Mizukami T, Liu Y, Wang Y, Xu G, Roder H, Zhang L, Yang ZJ
Cell death and differentiation 2023 May;30(5):1198-1210
Cell death and differentiation 2023 May;30(5):1198-1210
GNB1 promotes hepatocellular carcinoma progression by targeting BAG2 to activate P38/MAPK signaling.
Zhang X, Dong K, Zhang J, Kuang T, Luo Y, Yu J, Yu J, Wang W
Cancer science 2023 May;114(5):2001-2013
Cancer science 2023 May;114(5):2001-2013
CB2R activation ameliorates late adolescent chronic alcohol exposure-induced anxiety-like behaviors during withdrawal by preventing morphological changes and suppressing NLRP3 inflammasome activation in prefrontal cortex microglia in mice.
Li J, Wang H, Liu D, Li X, He L, Pan J, Shen Q, Peng Y
Brain, behavior, and immunity 2023 May;110:60-79
Brain, behavior, and immunity 2023 May;110:60-79
BACH1 deficiency prevents neointima formation and maintains the differentiated phenotype of vascular smooth muscle cells by regulating chromatin accessibility.
Guo J, Qiu J, Jia M, Li Q, Wei X, Li L, Pan Q, Jin J, Ge F, Ma S, He Y, Lin J, Li Y, Ma J, Jiang N, Zhi X, Jiang L, Zhang J, Osto E, Jing Q, Wang X, Meng D
Nucleic acids research 2023 May 22;51(9):4284-4301
Nucleic acids research 2023 May 22;51(9):4284-4301
IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma.
Zhang X, Wang G, Gong Y, Zhao L, Song P, Zhang H, Zhang Y, Ju H, Wang X, Wang B, Ren H, Zhu X, Dong Y
iScience 2023 May 19;26(5):106639
iScience 2023 May 19;26(5):106639
Estrogen-mediated oar-miR-485-5p targets PPP1R13B to regulate myoblast proliferation in sheep.
Liu S, Liu Z, Wang P, Li W, Zhao S, Liu Y, Chu M
International journal of biological macromolecules 2023 May 1;236:123987
International journal of biological macromolecules 2023 May 1;236:123987
VPS35 promotes cell proliferation via EGFR recycling and enhances EGFR inhibitors response in gastric cancer.
Yu J, Feng H, Sang Q, Li F, Chen M, Yu B, Xu Z, Pan T, Wu X, Hou J, Zhu Z, Yan C, Su L, Li J, Liu B
EBioMedicine 2023 Mar;89:104451
EBioMedicine 2023 Mar;89:104451
Stabilization of nuclear β-catenin by inhibiting KDM2A mediates cerebral ischemic tolerance.
Zuo Y, Zhan L, Wen H, Xue J, Tan Y, Sun W, Xu E
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22796
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22796
METTL3 promotes SMSCs chondrogenic differentiation by targeting the MMP3, MMP13, and GATA3.
Hu B, Zou X, Yu Y, Jiang Y, Xu H
Regenerative therapy 2023 Mar;22:148-159
Regenerative therapy 2023 Mar;22:148-159
IGF2 inhibits hippocampal over-activated microglia and alleviates depression-like behavior in LPS- treated male mice.
Guo D, Xu Y, Liu Z, Wang Y, Xu X, Li C, Li S, Zhang J, Xiong T, Cao W, Liang J
Brain research bulletin 2023 Mar;194:1-12
Brain research bulletin 2023 Mar;194:1-12
One Stone, Two Birds: A Peptide-Au(I) Infinite Coordination Supermolecule for the Confederate Physical and Biological Radiosensitization in Cancer Radiation Therapy.
Wang J, Zhao J, Ma F, Gong L, Lu Y, Xiao W, Tang H, Gao C, Chen Y, Ma J, Gao Z, Yan J, Han S
Small (Weinheim an der Bergstrasse, Germany) 2023 Mar;19(11):e2204238
Small (Weinheim an der Bergstrasse, Germany) 2023 Mar;19(11):e2204238
Artesunate, a new antimalarial clinical drug, exhibits potent anti-AML activity by targeting the ROS/Bim and TFRC/Fe(2+) pathways.
Liu Y, Li H, Luo Z, Yu Y, Yang J, Zhang M, Law BYK, Huang Z, Li W
British journal of pharmacology 2023 Mar;180(6):701-720
British journal of pharmacology 2023 Mar;180(6):701-720
Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage.
Qiu X, Tao Q, Zhang L, Kuang C, Xie Y, Zhang L, Yin S, Peng J, Jiang Y
Journal of neurochemistry 2023 Mar;164(6):829-846
Journal of neurochemistry 2023 Mar;164(6):829-846
Key domains and residues of the receptor MRGPRX1 recognizing the peptide ligand BAM8-22.
Hu J, Wang L, Yang H, Meng Y, Tao M, Wu Y, Cao Z
Peptides 2023 Mar;161:170927
Peptides 2023 Mar;161:170927
LncRNA SPRY4-IT1 facilitates cell proliferation and angiogenesis of glioma via the miR-101-3p/EZH2/VEGFA signaling axis.
Wang J, Chen Y, Wang Q, Xu H, Jiang Q, Wang M, Li S, Chen Y, Wu C, Yu P, Xiao Z, Chen W, Lan Q
Cancer medicine 2023 Mar;12(6):7309-7326
Cancer medicine 2023 Mar;12(6):7309-7326
PKCθ Regulates Pituitary Adenoma Bone Invasion by Activating Osteoclast in NF-κB/IL-1β-Dependent Manner.
Wang Q, Lei Z, Wang Z, Jiang Q, Zhang Z, Liu X, Xing B, Li S, Guo X, Liu Y, Li X, Shu K, Zhang H, Huang Y, Lei T
Cancers 2023 Mar 6;15(5)
Cancers 2023 Mar 6;15(5)
Deletion of Transglutaminase 2 from Mouse Astrocytes Significantly Improves Their Ability to Promote Neurite Outgrowth on an Inhibitory Matrix.
Emerson J, Delgado T, Girardi P, Johnson GVW
International journal of molecular sciences 2023 Mar 23;24(7)
International journal of molecular sciences 2023 Mar 23;24(7)
PDCD6 Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis through the AKT/GSK3β/β-catenin Pathway.
Wen SY, Liu YT, Wei BY, Ma JQ, Chen YY
Biomedical and environmental sciences : BES 2023 Mar 20;36(3):241-252
Biomedical and environmental sciences : BES 2023 Mar 20;36(3):241-252
Effects of Spatial Expression of Activating Transcription Factor 4 on the Pathogenicity of Two Phenotypes of Bovine Viral Diarrhea Virus by Regulating the Endoplasmic Reticulum-Mediated Autophagy Process.
Wang J, Chen KY, Wang SH, Liu Y, Zhao YQ, Yang L, Yang GH, Wang XJ, Zhu YH, Yin JH, Wang JF
Microbiology spectrum 2023 Mar 20;11(2):e0422522
Microbiology spectrum 2023 Mar 20;11(2):e0422522
1,2,4,5-Tetrazine-tethered probes for fluorogenically imaging superoxide in live cells with ultrahigh specificity.
Jiang X, Li M, Wang Y, Wang C, Wang Y, Shen T, Shen L, Liu X, Wang Y, Li X
Nature communications 2023 Mar 14;14(1):1401
Nature communications 2023 Mar 14;14(1):1401
Mechanism Repositioning Based on Integrative Pharmacology: Anti-Inflammatory Effect of Safflower in Myocardial Ischemia-Reperfusion Injury.
Zhao F, Jiang H, Zhang T, Chen H, Li W, Li X, Wang P, Xu H
International journal of molecular sciences 2023 Mar 10;24(6)
International journal of molecular sciences 2023 Mar 10;24(6)
Tibetan medicine Si-Wei-Qiang-Wei Powder ameliorates cholecystitis via inhibiting the production of pro-inflammatory cytokines and regulating the MAPK signaling pathway.
Zheng Z, Xiong H, Zhao Z, Zhou K, Fu M, Liu X, Mei Z
Journal of ethnopharmacology 2023 Mar 1;303:116026
Journal of ethnopharmacology 2023 Mar 1;303:116026
Decellularized brain extracellular matrix slice glioblastoma culture model recapitulates the interaction between cells and the extracellular matrix without a nutrient-oxygen gradient interference.
Wang C, Zhao Q, Zheng X, Li S, Chen J, Zhao H, Chen F, Cui L, Li W
Acta biomaterialia 2023 Mar 1;158:132-150
Acta biomaterialia 2023 Mar 1;158:132-150
The tick saliva peptide HIDfsin2 promotes the tick-borne virus SFTSV replication in vitro by enhancing p38 signal pathway.
Wang L, Sun F, Hu J, Zuo W, Zheng Y, Wu Y, Kwok HF, Cao Z
Archives of toxicology 2023 Jun;97(6):1783-1794
Archives of toxicology 2023 Jun;97(6):1783-1794
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.
Li K, Feng Z, Wang L, Ma X, Wang L, Liu K, Geng X, Peng C
Inflammation 2023 Jun;46(3):1061-1076
Inflammation 2023 Jun;46(3):1061-1076
Magnify is a universal molecular anchoring strategy for expansion microscopy.
Klimas A, Gallagher BR, Wijesekara P, Fekir S, DiBernardo EF, Cheng Z, Stolz DB, Cambi F, Watkins SC, Brody SL, Horani A, Barth AL, Moore CI, Ren X, Zhao Y
Nature biotechnology 2023 Jun;41(6):858-869
Nature biotechnology 2023 Jun;41(6):858-869
Proteomics Profiling Reveals the Molecular Signatures and Potential Therapeutic Targets of Human Nasopharyngeal Carcinoma.
Fu Y, Liang X, Yang X, Liu J, Huang H, Zhang P, Li S, Zhu D, Zhang Y, Peng F, Chen Y, Chen Z
Molecular & cellular proteomics : MCP 2023 Jun;22(6):100567
Molecular & cellular proteomics : MCP 2023 Jun;22(6):100567
Chromatin remodeling and nucleoskeleton synergistically control osteogenic differentiation in different matrix stiffnesses.
Xu X, Zhang H, Li Y, Liu F, Jing Z, Ren M, Chen T, Fu Y, Wu Y, Ji P, Yang S
Materials today. Bio 2023 Jun;20:100661
Materials today. Bio 2023 Jun;20:100661
Amyloid futures in the expanding pathology of brain aging and dementia.
Thorwald MA, Silva J, Head E, Finch CE
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Jun;19(6):2605-2617
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Jun;19(6):2605-2617
Ginsenoside Rb1 improves energy metabolism after spinal cord injury.
Wen S, Zou ZR, Cheng S, Guo H, Hu HS, Zeng FZ, Mei XF
Neural regeneration research 2023 Jun;18(6):1332-1338
Neural regeneration research 2023 Jun;18(6):1332-1338
Low rumen degradable starch promotes the growth performance of goats by increasing protein synthesis in skeletal muscle via the AMPK-mTOR pathway.
Liang Z, Jin C, Bai H, Liang G, Su X, Wang D, Yao J
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Jun;13:1-8
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Jun;13:1-8
Docosahexaenoic Acid Alters Lipid Metabolism Processes via H3K9ac Epigenetic Modification in Dairy Goat.
Wu J, Luo J, He Q, Xia Y, Tian H, Zhu L, Li C, Loor JJ
Journal of agricultural and food chemistry 2023 Jun 7;71(22):8527-8539
Journal of agricultural and food chemistry 2023 Jun 7;71(22):8527-8539
Endothelial progenitor cell-derived exosomes promote anti-inflammatory macrophages via SOCS3/JAK2/STAT3 axis and improve the outcome of spinal cord injury.
Yuan F, Peng W, Yang Y, Xu J, Liu Y, Xie Y, Huang T, Shi C, Ding Y, Li C, Qin T, Xie S, Zhu F, Lu H, Huang J, Hu J
Journal of neuroinflammation 2023 Jun 30;20(1):156
Journal of neuroinflammation 2023 Jun 30;20(1):156
DnaJC7 specifically regulates tau seeding.
Perez VA, Sanders DW, Mendoza-Oliva A, Stopschinski BE, Mullapudi V, White CL, Joachimiak LA, Diamond MI
eLife 2023 Jun 30;12
eLife 2023 Jun 30;12
Tumor-Associated Fibroblast-Derived Exosomal circDennd1b Promotes Pituitary Adenoma Progression by Modulating the miR-145-5p/ONECUT2 Axis and Activating the MAPK Pathway.
Jiang Q, Lei Z, Wang Z, Wang Q, Zhang Z, Liu X, Xing B, Li S, Guo X, Liu Y, Li X, Qi Y, Shu K, Zhang H, Huang Y, Lei T
Cancers 2023 Jun 27;15(13)
Cancers 2023 Jun 27;15(13)
FBXO28 promotes proliferation, invasion, and metastasis of pancreatic cancer cells through regulation of SMARCC2 ubiquitination.
Liu S, Liu P, Zhu C, Yang R, He Z, Li Y, Li Y, Fei X, Hou J, Wang X, Pan Y
Aging 2023 Jun 21;15(12):5381-5398
Aging 2023 Jun 21;15(12):5381-5398
Scarless wound healing programmed by core-shell microneedles.
Zhang Y, Wang S, Yang Y, Zhao S, You J, Wang J, Cai J, Wang H, Wang J, Zhang W, Yu J, Han C, Zhang Y, Gu Z
Nature communications 2023 Jun 10;14(1):3431
Nature communications 2023 Jun 10;14(1):3431
Hydrogen sulfide antagonizes formaldehyde-induced ferroptosis via preventing ferritinophagy by upregulation of GDF11 in HT22 cells.
Tang YH, Wu L, Huang HL, Zhang PP, Zou W, Tang XQ, Tang YY
Toxicology 2023 Jun 1;491:153517
Toxicology 2023 Jun 1;491:153517
ORP8 inhibits renal cell carcinoma progression by accelerating Stathmin1 degradation and microtubule polymerization.
Zhang L, Pan Q, Wu Y, Zhang P, Li S, Xu Y, Li D, Zheng M, Pei D, Wang Q
Experimental cell research 2023 Jun 1;427(1):113601
Experimental cell research 2023 Jun 1;427(1):113601
Exosomes derived from oral squamous cell carcinoma tissue accelerate diabetic wound healing.
Zhang M, Guo J, Xiang K, Chen J, Wang C, Jiang T, Kang Y, Xu X, Li J, Yang X, Chen Z
American journal of physiology. Cell physiology 2023 Jun 1;324(6):C1307-C1319
American journal of physiology. Cell physiology 2023 Jun 1;324(6):C1307-C1319
The distinct initiation sites and processing activities of TTLL4 and TTLL7 in glutamylation of brain tubulin.
Zhang X, Li X, Chen W, Wang Y, Diao L, Gao Y, Wang H, Bao L, Liang X, Wu HY
The Journal of biological chemistry 2023 Jul;299(7):104923
The Journal of biological chemistry 2023 Jul;299(7):104923
MRPL51 is a downstream target of FOXM1 in promoting the malignant behaviors of lung adenocarcinoma.
Zhang W, Yu L, Xu C, Tang T, Cao J, Chen L, Pang X, Ren W
Oncology letters 2023 Jul;26(1):298
Oncology letters 2023 Jul;26(1):298
Anisomycin inhibits Coxsackievirus B replication by promoting the lysosomal degradation of eEF1A1.
Shao E, Zhao S, Dong Y, Wang Y, Fei Y, Li S, Wang L, Bashir T, Luan T, Lin L, Wang Y, Zhao W, Zhong Z
Antiviral research 2023 Jul;215:105621
Antiviral research 2023 Jul;215:105621
TANGO1 interacts with NRTN to promote hepatocellular carcinoma progression by regulating the PI3K/AKT/mTOR signaling pathway.
Man J, Zhou W, Zuo S, Zhao X, Wang Q, Ma H, Li HY
Biochemical pharmacology 2023 Jul;213:115615
Biochemical pharmacology 2023 Jul;213:115615
Neotuberostemonine and tuberostemonine ameliorate pulmonary fibrosis through suppressing TGF-β and SDF-1 secreted by macrophages and fibroblasts via the PI3K-dependent AKT and ERK pathways.
Fu S, Song X, Hu Y, Zhu Q, Lv X, Tang X, Zhang M
Chinese journal of natural medicines 2023 Jul;21(7):527-539
Chinese journal of natural medicines 2023 Jul;21(7):527-539
Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3-NFS1 axis in doxorubicin-induced cardiotoxicity.
Wang Y, Ying X, Wang Y, Zou Z, Yuan A, Xiao Z, Geng N, Qiao Z, Li W, Lu X, Pu J
Cellular signalling 2023 Jul;107:110655
Cellular signalling 2023 Jul;107:110655
Tumor necrosis factor-α reduces adiponectin production by decreasing transcriptional activity of peroxisome proliferator-activated receptor-γ in calf adipocytes.
Yu H, Gao X, Ge Q, Tai W, Hao X, Shao Q, Fang Z, Chen M, Song Y, Gao W, Liu G, Du X, Li X
Journal of dairy science 2023 Jul;106(7):5182-5195
Journal of dairy science 2023 Jul;106(7):5182-5195
Expression and Activity of the Transcription Factor CCAAT/Enhancer-Binding Protein β (C/EBPβ) Is Regulated by Specific Pulse-Modulated Radio Frequencies in Oligodendroglial Cells.
Huang B, Zhao W, Cai X, Zhu Y, Lu Y, Zhao J, Xiang N, Wang X, Deng H, Tang X, Liu L, Zhao Y, Shi Y
International journal of molecular sciences 2023 Jul 5;24(13)
International journal of molecular sciences 2023 Jul 5;24(13)
Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer.
Li X, Li F, Ye F, Guo H, Chen W, Jin J, Wang Y, Dai P, Shi H, Tao H, Dang W, Ding Y, Wang M, Jiang H, Chen K, Zhang N, Gao D, Zhang Y, Luo C
Cell reports 2023 Jul 25;42(7):112798
Cell reports 2023 Jul 25;42(7):112798
αKG-driven RNA polymerase II transcription of cyclin D1 licenses malic enzyme 2 to promote cell-cycle progression.
Yang Y, Zhang Z, Li W, Si Y, Li L, Du W
Cell reports 2023 Jul 25;42(7):112770
Cell reports 2023 Jul 25;42(7):112770
Neobavaisoflavone induces pyroptosis of liver cancer cells via Tom20 sensing the activated ROS signal.
Li Y, Zhao R, Xiu Z, Yang X, Zhu Y, Han J, Li S, Li Y, Sun L, Li X, Jin N, Li Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154869
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154869
Transcriptional analysis of the expression and prognostic value of lipid droplet-localized proteins in hepatocellular carcinoma.
Zhang Y, Liang X, Lian Q, Liu L, Zhang B, Dong Z, Liu K
BMC cancer 2023 Jul 18;23(1):677
BMC cancer 2023 Jul 18;23(1):677
Triptolide with hepatotoxicity and nephrotoxicity used in local delivery treatment of myocardial infarction by thermosensitive hydrogel.
Wang K, Zhu K, Zhu Z, Shao F, Qian R, Wang C, Dong H, Li Y, Gao Z, Zhao J
Journal of nanobiotechnology 2023 Jul 17;21(1):227
Journal of nanobiotechnology 2023 Jul 17;21(1):227
PPARα is involved in high-fat diet-induced risk avoidance impairment via the regulation of hippocampal BDNF.
Zhu XY, Luo J, Wei XJ, Pan LH, Xu XF, Hu LB, Dong YB, Jiang YK, Dong FY, Xu L, Xu LM, Liu AM, Zhang XQ
Food & function 2023 Jul 17;14(14):6541-6553
Food & function 2023 Jul 17;14(14):6541-6553
Small intestine submucosa as a growth factor attractor promotes peripheral nerve regeneration by enhancing syndecan-3/glial cell line-derived neurotrophic factor (GDNF) signalling:in vivostudy().
Liu CH, Chu YH, Chen YH, Chiang YH, Chen YH, Ku CY, Hsu MY, Lee YJ, Yang MY, Liao WC
Biomedical materials (Bristol, England) 2023 Jul 12;18(5)
Biomedical materials (Bristol, England) 2023 Jul 12;18(5)
Resveratrol-loaded macrophage exosomes alleviate multiple sclerosis through targeting microglia.
Zheng X, Sun K, Liu Y, Yin X, Zhu H, Yu F, Zhao W
Journal of controlled release : official journal of the Controlled Release Society 2023 Jan;353:675-684
Journal of controlled release : official journal of the Controlled Release Society 2023 Jan;353:675-684
Dexmedetomidine attenuates airway inflammation and oxidative stress in asthma via the Nrf2 signaling pathway.
Xiao S, Zhou Y, Gao H, Yang D
Molecular medicine reports 2023 Jan;27(1)
Molecular medicine reports 2023 Jan;27(1)
Inhibition of deubiquitinase USP28 attenuates cyst growth in autosomal dominant polycystic kidney disease.
Ren Y, Zhu X, Fu K, Zhang H, Zhao W, Lin Y, Fang Q, Wang J, Chen Y, Guo D
Biochemical pharmacology 2023 Jan;207:115355
Biochemical pharmacology 2023 Jan;207:115355
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
Tong F, Zhao JX, Fang ZY, Cui XT, Su DY, Liu X, Zhou JH, Wang GX, Qiu ZJ, Liu SZ, Fu JQ, Kang CS, Wang JC, Wang QX
Pharmacological research 2023 Jan;187:106606
Pharmacological research 2023 Jan;187:106606
Pine pollen extract alleviates ethanol-induced oxidative stress and apoptosis in HepG2 cells via MAPK signaling.
Ma D, Wang Z, He Z, Wang Z, Chen Q, Qin F, Zeng M, Chen J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jan;171:113550
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jan;171:113550
Zcf24, a zinc-finger transcription factor, is required for lactate catabolism and inhibits commensalism in Candida albicans.
Sun Q, Dong B, Yang D, Yu J, Ren T, Wang T, Yang L, Lu Y, Su C
Molecular microbiology 2023 Jan;119(1):112-125
Molecular microbiology 2023 Jan;119(1):112-125
Low-Dose Radiation Reduces Doxorubicin-Induced Myocardial Injury Through Mitochondrial Pathways.
Zhao D, Jiang X, Meng X, Liu D, Du Y, Zhao L, Jiang H
Dose-response : a publication of International Hormesis Society 2023 Jan-Mar;21(1):15593258231155789
Dose-response : a publication of International Hormesis Society 2023 Jan-Mar;21(1):15593258231155789
Transcription factor ETS proto-oncogene 1 contributes to neuropathic pain by regulating histone deacetylase 1 in primary afferent neurons.
Zheng HL, Sun SY, Jin T, Zhang M, Zeng Y, Liu Q, Yang K, Wei R, Pan Z, Lin F
Molecular pain 2023 Jan-Dec;19:17448069231152125
Molecular pain 2023 Jan-Dec;19:17448069231152125
Exosomal-miR-129-2-3p derived from Fusobacterium nucleatum-infected intestinal epithelial cells promotes experimental colitis through regulating TIMELESS-mediated cellular senescence pathway.
Wei S, Wu X, Chen M, Xiang Z, Li X, Zhang J, Dong W
Gut microbes 2023 Jan-Dec;15(1):2240035
Gut microbes 2023 Jan-Dec;15(1):2240035
Resveratrol Modulates the Redox Response and Bile Acid Metabolism to Maintain the Cholesterol Homeostasis in Fish Megalobrama amblycephala Offered a High-Carbohydrate Diet.
Ge Y, Zhang L, Chen W, Sun M, Liu W, Li X
Antioxidants (Basel, Switzerland) 2023 Jan 3;12(1)
Antioxidants (Basel, Switzerland) 2023 Jan 3;12(1)
Network Pharmacology and Experimental Verification to Unveil the Mechanism of N-Methyl-D-Aspartic Acid Rescue Humantenirine-Induced Excitotoxicity.
Qi XJ, Huang CY, Zuo MT, Gong MD, Huang SJ, Tang MH, Liu ZY
Metabolites 2023 Jan 28;13(2)
Metabolites 2023 Jan 28;13(2)
Marine-Derived Natural Product HDYL-GQQ-495 Targets P62 to Inhibit Autophagy.
Li Q, Fan J, Chen Y, Liu Y, Liu H, Jiang W, Li D, Dang Y
Marine drugs 2023 Jan 20;21(2)
Marine drugs 2023 Jan 20;21(2)
Jatrorrhizine Suppresses Murine-Norovirus-Triggered N-GSDMD-Dependent Pyroptosis in RAW264.7 Macrophages.
Fu M, Chen N, Zhou Y, Chen S, Xu W, Gong S, Geng L
Vaccines 2023 Jan 12;11(1)
Vaccines 2023 Jan 12;11(1)
Anti-inflammatory and osteoprotective effects of Shi-Wei-Ru-Xiang pills on collagen-induced arthritis in rats via inhibiting MAPK and STAT3 pathways.
Xiong H, Meng F, Luo M, Chen W, Tian J, Chen L, Ju Y, Mei Z
Journal of ethnopharmacology 2023 Jan 10;300:115693
Journal of ethnopharmacology 2023 Jan 10;300:115693
Polydopamine-Decorated PLCL Conduit to Induce Synergetic Effect of Electrical Stimulation and Topological Morphology for Peripheral Nerve Regeneration.
Lu S, Chen W, Wang J, Guo Z, Xiao L, Wei L, Yu J, Yuan Y, Chen W, Bian M, Huang L, Liu Y, Zhang J, Li YL, Jiang LB
Small methods 2023 Feb;7(2):e2200883
Small methods 2023 Feb;7(2):e2200883
Zinc Promotes Spinal Cord Injury Recovery by Blocking the Activation of NLRP3 Inflammasome Through SIRT3-Mediated Autophagy.
Xu C, Zhou Z, Zhao H, Lin S, Zhang P, Tian H, Mei X
Neurochemical research 2023 Feb;48(2):435-446
Neurochemical research 2023 Feb;48(2):435-446
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
Wang J, Xu J, Dong Y, Su Z, Su H, Cheng Q, Liu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
3, 14, 19-Triacetyl Andrographolide alleviates the cognitive dysfunction of 3 × Tg-AD mice by inducing initiation and promoting degradation process of autophagy.
Zhang H, Xie X, Shi J, Zhao Q, Luo D, Hao J, Zhou Y, Han G, Pang X
Phytotherapy research : PTR 2023 Feb;37(2):410-423
Phytotherapy research : PTR 2023 Feb;37(2):410-423
Mechanism of YY1 mediating autophagy dependent ferroptosis in PM2.5 induced cardiac fibrosis.
Hu H, Li L, Zhang H, Zhang Y, Liu Q, Chen M, Ning J, Pang Y, Hu W, Niu Y, Zhang R
Chemosphere 2023 Feb;315:137749
Chemosphere 2023 Feb;315:137749
Collagen type Ⅰ-loaded methacrylamide hyaluronic acid hydrogel microneedles alleviate stress urinary incontinence in mice: A novel treatment and prevention strategy.
Zhang S, Yang L, Hong S, Liu J, Cheng J, He Y, Hong L
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113085
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113085
Bacterial infection promotes tumorigenesis of colorectal cancer via regulating CDC42 acetylation.
Wang DN, Ni JJ, Li JH, Gao YQ, Ni FJ, Zhang ZZ, Fang JY, Lu J, Yao YF
PLoS pathogens 2023 Feb;19(2):e1011189
PLoS pathogens 2023 Feb;19(2):e1011189
Mutation of the attractin gene impairs working memory in rats.
Liu MQ, Xue C, Li XH, Ding HQ, Zhang MY, Chen K, Li Y, Gao SZ, Xu XJ, Zhang WN
Brain and behavior 2023 Feb;13(2):e2876
Brain and behavior 2023 Feb;13(2):e2876
Revealing active components and action mechanism of Fritillariae Bulbus against non-small cell lung cancer through spectrum-effect relationship and proteomics.
Liu FJ, Chen XY, Yang J, Zhao Z, Wang QL, Li P, Jiang Y, Li HJ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Feb;110:154635
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Feb;110:154635
TIPE2 deletion improves the therapeutic potential of adoptively transferred NK cells.
Bi J, Huang C, Jin X, Zheng C, Huang Y, Zheng X, Tian Z, Sun H
Journal for immunotherapy of cancer 2023 Feb;11(2)
Journal for immunotherapy of cancer 2023 Feb;11(2)
Baricitinib Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice by Inhibiting TGF-β1 Signaling Pathway.
Gu S, Liang J, Zhang J, Liu Z, Miao Y, Wei Y, Li S, Gu J, Cui Y, Xiao T, Li X, Yang C
Molecules (Basel, Switzerland) 2023 Feb 27;28(5)
Molecules (Basel, Switzerland) 2023 Feb 27;28(5)
Peroxiredoxin-6 Released by Astrocytes Contributes to Neuroapoptosis During Ischemia.
Hou JY, Zhou XL, Wang XY, Liang J, Xue Q
Neuroscience 2023 Feb 21;512:59-69
Neuroscience 2023 Feb 21;512:59-69
Site-specific phosphorylation of tau impacts mitochondrial biology and response to stressors.
Isei MO, Girardi PA, Rodwell-Bullock J, Nehrke K, Johnson GV
bioRxiv : the preprint server for biology 2023 Feb 19;
bioRxiv : the preprint server for biology 2023 Feb 19;
SECTM1 is upregulated in immuno-hot tumors and predicts immunotherapeutic efficacy in multiple cancers.
Mei J, Fu Z, Cai Y, Song C, Zhou J, Zhu Y, Mao W, Xu J, Yin Y
iScience 2023 Feb 17;26(2):106027
iScience 2023 Feb 17;26(2):106027
Hyperactivation of TRPV4 causes the hippocampal pyroptosis pathway and results in cognitive impairment in LPS-treated mice.
Guo D, Xu Y, Wang Y, Zhong X, Liu Z, Li S, Xu X, Zhang J, Xiong T, Cao W, Liang J
Behavioural brain research 2023 Feb 15;439:114223
Behavioural brain research 2023 Feb 15;439:114223
Design, synthesis and biological evaluation of novel phenylfuran-bisamide derivatives as P-glycoprotein inhibitors against multidrug resistance in MCF-7/ADR cell.
Yang Z, Yang X, Li Y, Cai Y, Yu Y, Zhuang W, Sun X, Li Q, Bao X, Ye X, Tian J, Wei B, Chen J, Wu Q, Zhang H, Mou X, Wang H
European journal of medicinal chemistry 2023 Feb 15;248:115092
European journal of medicinal chemistry 2023 Feb 15;248:115092
microRNA-627-5p inhibits colorectal cancer cell proliferation, migration and invasion by targeting Wnt2.
Zhao DY, Yin TF, Sun XZ, Zhou YC, Wang QQ, Zhou GY, Yao SK
World journal of gastrointestinal oncology 2023 Feb 15;15(2):318-331
World journal of gastrointestinal oncology 2023 Feb 15;15(2):318-331
A Novel Prenylflavonoid Icariside I Ameliorates Estrogen Deficiency-Induced Osteoporosis via Simultaneous Regulation of Osteoblast and Osteoclast Differentiation.
Chen C, Wu M, Lei H, Cao Z, Wu F, Song Y, Zhang C, Qin M, Zhang C, Du R, Zhou J, Lu Y, Xie D, Zhang L
ACS pharmacology & translational science 2023 Feb 10;6(2):270-280
ACS pharmacology & translational science 2023 Feb 10;6(2):270-280
Si-Ni-SAN ameliorates obesity through AKT/AMPK/HSL pathway-mediated lipolysis: Network pharmacology and experimental validation.
Li J, Wu K, Zhong Y, Kuang J, Huang N, Guo X, Du H, Guo C, Li R, Zhu X, Zhang T, Gong L, Sheng L, Sun R
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115892
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115892
UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.
Hong X, Ma N, Li D, Zhang M, Dong W, Huang J, Ci X, Zhang S
Cell death & disease 2023 Feb 10;14(2):100
Cell death & disease 2023 Feb 10;14(2):100
Knockout of transient receptor potential ankyrin 1 (TRPA1) modulates the glial phenotype and alleviates perihematomal neuroinflammation after intracerebral hemorrhage in mice via MAPK/NF-κB signaling.
Xia M, Chen YJ, Chen B, Ru X, Wang J, Lin J, Tang X, Chen W, Hu R, Li W, Feng H
Neuroreport 2023 Feb 1;34(2):81-92
Neuroreport 2023 Feb 1;34(2):81-92
ADAMTS7-Mediated Complement Factor H Degradation Potentiates Complement Activation to Contributing to Renal Injuries.
Ma Z, Mao C, Jia Y, Yu F, Xu P, Tan Y, Zou QH, Zhou XJ, Kong W, Fu Y
Journal of the American Society of Nephrology : JASN 2023 Feb 1;34(2):291-308
Journal of the American Society of Nephrology : JASN 2023 Feb 1;34(2):291-308
TBC1 domain family member 25 protects against myocardial apoptosis and the proinflammatory response triggered by ischemia-reperfusion injury through suppression of the TAK1-JNK/p38 MAPK signaling cascade.
Liu Z, Shang F, Li N, Dong W
In vitro cellular & developmental biology. Animal 2023 Dec;59(10):796-810
In vitro cellular & developmental biology. Animal 2023 Dec;59(10):796-810
White adipose tissue-derived small extracellular vesicles: A new potential therapeutic reagent for accelerating diabetic wound healing.
Zhang C, Jiang T, Jiang G, Xu X, Yan C, Kang Y, Xiang X, Liu S, Nie P, Zhang M, Chen J, Yuan M, Xu Y, Yang X, Chen Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Dec;37(12):e23314
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Dec;37(12):e23314
Exogenous H(2) S promotes ubiquitin-mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S-sulfhydration.
Zhang S, Wang M, Li H, Li Q, Liu N, Dong S, Zhao Y, Pang K, Huang J, Ren C, Wang Y, Tian Z, Lu F, Zhang W
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2719-2732
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2719-2732
Succinate-induced macrophage polarization and RBP4 secretion promote vascular sprouting in ocular neovascularization.
Shen T, Lin R, Hu C, Yu D, Ren C, Li T, Zhu M, Wan Z, Su T, Wu Y, Cai W, Yu J
Journal of neuroinflammation 2023 Dec 21;20(1):308
Journal of neuroinflammation 2023 Dec 21;20(1):308
MRPL48 is a novel prognostic and predictive biomarker of hepatocellular carcinoma.
Lin YX, Pan JY, Feng WD, Huang TC, Li CZ
European journal of medical research 2023 Dec 14;28(1):589
European journal of medical research 2023 Dec 14;28(1):589
Piezo1 suppression reduces demyelination after intracerebral hemorrhage.
Qu J, Zong HF, Shan Y, Zhang SC, Guan WP, Yang Y, Zhao HL
Neural regeneration research 2023 Aug;18(8):1750-1756
Neural regeneration research 2023 Aug;18(8):1750-1756
MicroRNA‑30a‑5p regulates cypermethrin-induced apoptosis of Sertoli cells by targeting KLF9 in vitro.
Wang Q, Xie JF, Yao TT, Wang XX, Guo QW, Wang LS, Yu Y, Xu LC
Reproductive toxicology (Elmsford, N.Y.) 2023 Aug;119:108414
Reproductive toxicology (Elmsford, N.Y.) 2023 Aug;119:108414
MicroRNA-144-3p protects against chemotherapy-induced apoptosis of ovarian granulosa cells and activation of primordial follicles by targeting MAP3K9.
Liu M, Xiao B, Zhu Y, Chen M, Huang J, Guo H, Wang F
European journal of medical research 2023 Aug 3;28(1):264
European journal of medical research 2023 Aug 3;28(1):264
CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway.
Ji HZ, Chen L, Ren M, Li S, Liu TY, Chen HJ, Yu HH, Sun Y
Pharmaceuticals (Basel, Switzerland) 2023 Aug 25;16(9)
Pharmaceuticals (Basel, Switzerland) 2023 Aug 25;16(9)
LncRNA SOCS2-AS1 promotes the progression of papillary thyroid cancer by destabilizing p53 protein.
Zhang X, Zhang X, Yang G, Wan L, Yin F, Li H, Yin D
Biochemical and biophysical research communications 2023 Aug 20;669:95-102
Biochemical and biophysical research communications 2023 Aug 20;669:95-102
TM6SF2 reduces lipid accumulation in vascular smooth muscle cells by inhibiting LOX-1 and CD36 expression.
Li TT, Cui YT, Li TH, Xiang Q, Chen YY, Zheng XL, Peng J, Tang ZH
Experimental cell research 2023 Aug 15;429(2):113666
Experimental cell research 2023 Aug 15;429(2):113666
Progressive Thinning of Retinal Nerve Fiber Layer/Ganglion Cell Layer (RNFL/GCL) as Biomarker and Pharmacological Target of Diabetic Retinopathy.
Zerbini G, Maestroni S, Viganò I, Mosca A, Paleari R, Gabellini D, Galbiati S, Rama P
International journal of molecular sciences 2023 Aug 11;24(16)
International journal of molecular sciences 2023 Aug 11;24(16)
Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.
Zhang Y, Wang S, Dai X, Liu T, Liu Y, Shi H, Yin J, Xu T, Zhang Y, Zhao D, Sukhorukov V, Orekhov AN, Gao S, Wang L, Zhang D
Journal of ethnopharmacology 2023 Aug 10;312:116530
Journal of ethnopharmacology 2023 Aug 10;312:116530
Apolipoprotein E Polymorphism Impacts White Matter Injury Through Microglial Phagocytosis After Experimental Subarachnoid Hemorrhage.
Li C, Lu P, Zhang L, He Y, Zhang L, Yang L, Zhang F, Kong X, Tao Q, Zhou J, Wu J, Peng T, Xie B, Jiang Y, Peng J
Neuroscience 2023 Aug 1;524:220-232
Neuroscience 2023 Aug 1;524:220-232
Systemic treatment with GnRH agonist produces antidepressant-like effects in LPS induced depression male mouse model.
Xu Y, Li W, Shi M, Xu X, Guo D, Liu Z, Chen L, Zhong X, Cao W
Neuropharmacology 2023 Aug 1;233:109560
Neuropharmacology 2023 Aug 1;233:109560
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.
Wang J, Cheng Q, Zhang Y, Hong C, Liu J, Liu X, Chang J
Aging and disease 2023 Aug 1;14(4):1458-1471
Aging and disease 2023 Aug 1;14(4):1458-1471
SIRT1 attenuates blood-spinal cord barrier disruption after spinal cord injury by deacetylating p66Shc.
Jiang T, Qin T, Gao P, Tao Z, Wang X, Wu M, Gu J, Chu B, Zheng Z, Yi J, Xu T, Huang Y, Liu H, Zhao S, Ren Y, Chen J, Yin G
Redox biology 2023 Apr;60:102615
Redox biology 2023 Apr;60:102615
In silico, in vitro and in vivo studies: Dibutyl phthalate promotes prostate cancer cell proliferation by activating Forkhead Box M1 and remission after Natura-α pretreatment.
Bu H, Tang S, Liu G, Miao C, Zhou X, Yang H, Liu B
Toxicology 2023 Apr;488:153465
Toxicology 2023 Apr;488:153465
Vagus nerve stimulation is a potential treatment for ischemic stroke.
Liu YL, Wang SR, Ma JX, Yu LH, Jia GW
Neural regeneration research 2023 Apr;18(4):825-831
Neural regeneration research 2023 Apr;18(4):825-831
Association between F-box-only protein 43 overexpression and hepatocellular carcinoma pathogenesis and prognosis.
Wu S, Qin L, Yang J, Wang J, Shen Y
Cancer medicine 2023 Apr;12(8):10062-10076
Cancer medicine 2023 Apr;12(8):10062-10076
Dual-specificity phosphatase 26-dificient neurons are susceptible to oxygen-glucose deprivation/reoxygenation-evoked apoptosis and proinflammatory response by affecting the TAK1-medaited JNK/P38 MAPK pathway.
Zhao H, Lv J, Meng L, Lv J, Li Z
International immunopharmacology 2023 Apr;117:109980
International immunopharmacology 2023 Apr;117:109980
The dichloromethane extract of Callicarpa longissima rich in diterpenoid phenols exerts anti-inflammatory effect via inhibiting the TLR4/NF-κB signaling pathway.
Li LC, Fu YX, Ning DS, Yu LL, Zou ZQ, Pan ZH
Journal of ethnopharmacology 2023 Apr 6;305:116124
Journal of ethnopharmacology 2023 Apr 6;305:116124
Enhanced E6AP-mediated ubiquitination of ENO1 via LINC00663 contributes to radiosensitivity of breast cancer by regulating mitochondrial homeostasis.
Ma J, Zhu J, Li J, Liu J, Kang X, Yu J
Cancer letters 2023 Apr 28;560:216118
Cancer letters 2023 Apr 28;560:216118
Novel Benzo Five-Membered Heterocycle Derivatives as P-Glycoprotein Inhibitors: Design, Synthesis, Molecular Docking, and Anti-Multidrug Resistance Activity.
Yang Z, Cai Y, Yang X, Li Y, Wu Q, Yu Y, Chen Z, Wei B, Tian JM, Bao X, Ye X, Chen J, Zhang H, Mou X, Sun X, Wang H
Journal of medicinal chemistry 2023 Apr 27;66(8):5550-5566
Journal of medicinal chemistry 2023 Apr 27;66(8):5550-5566
Acinous cell AR42J-derived exosome miR125b-5p promotes acute pancreatitis exacerbation by inhibiting M2 macrophage polarization via PI3K/AKT signaling pathway.
Zheng Z, Cao F, Ding YX, Lu JD, Fu YQ, Liu L, Guo YL, Liu S, Sun HC, Cui YQ, Li F
World journal of gastrointestinal surgery 2023 Apr 27;15(4):600-620
World journal of gastrointestinal surgery 2023 Apr 27;15(4):600-620
Targeting Chondroitin Sulphate Synthase 1 (Chsy1) Promotes Axon Growth Following Neurorrhaphy by Suppressing Versican Accumulation.
Liu CH, Ho YJ, Wang CY, Hsu CC, Chu YH, Hsu MY, Chen SJ, Hsiao WC, Liao WC
Molecules (Basel, Switzerland) 2023 Apr 26;28(9)
Molecules (Basel, Switzerland) 2023 Apr 26;28(9)
A conditional knockout rat resource of mitochondrial protein-coding genes via a DdCBE-induced premature stop codon.
Tan L, Qi X, Kong W, Jin J, Lu D, Zhang X, Wang Y, Wang S, Dong W, Shi X, Chen W, Wang J, Li K, Xie Y, Gao L, Guan F, Gao K, Li C, Wang C, Hu Z, Zhang L, Guo X, Shen B, Ma Y
Science advances 2023 Apr 14;9(15):eadf2695
Science advances 2023 Apr 14;9(15):eadf2695
ME2 Promotes Hepatocellular Carcinoma Cell Migration through Pyruvate.
Yang Y, Zhang Z, Li W, Li L, Zhou Y, Du W
Metabolites 2023 Apr 10;13(4)
Metabolites 2023 Apr 10;13(4)
TET1-TRPV4 Signaling Contributes to Bone Cancer Pain in Rats.
Xu ZH, Niu Z, Liu Y, Liu PL, Lin XL, Zhang L, Chen L, Song Y, Sun R, Zhang HL
Brain sciences 2023 Apr 10;13(4)
Brain sciences 2023 Apr 10;13(4)
Antidepressant-like effect of acute dose of Naringin involves suppression of NR1 and activation of protein kinase A/cyclic adenosine monophosphate response element-binding protein/brain-derived neurotrophic factor signaling in hippocampus.
Wang G, Yang H, Zuo W, Mei X
Behavioural pharmacology 2023 Apr 1;34(2-3):101-111
Behavioural pharmacology 2023 Apr 1;34(2-3):101-111
The preventive and therapeutic effect of repetitive transcranial magnetic stimulation on radiation-induced brain injury in mice.
Liu LY, Qin TZ, Guo L, Rong-Rong H, Jing YT, Lai PP, Xue YZ, Ding GR
International journal of radiation biology 2022;98(8):1316-1329
International journal of radiation biology 2022;98(8):1316-1329
Selective Inhibition of Histone Deacetylase Class IIa With MC1568 Ameliorates Podocyte Injury.
He X, Sun T, Zhang P, Xia Z, Gao C, Ren H, Ji D
Frontiers in medicine 2022;9:848938
Frontiers in medicine 2022;9:848938
Copy Number Analyses Identified a Novel Gene: APOBEC3A Related to Lipid Metabolism in the Pathogenesis of Preeclampsia.
Liu N, Guo YN, Wang XJ, Ma J, He YT, Zhang F, He H, Xie JL, Zhuang X, Liu M, Sun JH, Chen Y, Lin JH, Gong LK, Wang BS
Frontiers in cardiovascular medicine 2022;9:841249
Frontiers in cardiovascular medicine 2022;9:841249
Activation of Transcription Factor EB Is Associated With Adipose Tissue Lipolysis in Dairy Cows With Subclinical Ketosis.
Yu H, Gao X, Loor JJ, Jiang Q, Fang Z, Hao X, Shi Z, Fan M, Chen M, Li X, Liu G, Wang Z, Li X, Du X
Frontiers in veterinary science 2022;9:816064
Frontiers in veterinary science 2022;9:816064
The Hair Growth-Promoting Effect of Gardenia florida Fruit Extract and Its Molecular Regulation.
Liu X, Ji T, Hu H, Lv X, Zhu G
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8498974
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8498974
Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK.
Chen C, Chen Y, Liu T, Song D, Ma D, Cheng O
Oxidative medicine and cellular longevity 2022;2022:7511393
Oxidative medicine and cellular longevity 2022;2022:7511393
Epoxyeicosatrienoic Acids Inhibit the Activation of Murine Fibroblasts by Blocking the TGF-β1-Smad2/3 Signaling in a PPARγ-Dependent Manner.
Tao JH, Liu T, Zhang CY, Zu C, Yang HH, Liu YB, Yang JT, Zhou Y, Guan CX
Oxidative medicine and cellular longevity 2022;2022:7265486
Oxidative medicine and cellular longevity 2022;2022:7265486
Identifying Potential Tumor Antigens and Antigens-Related Subtypes in Hepatocellular Carcinoma for mRNA Vaccine Development.
Liao W, Shi Z, Tang H, Wu T, Zhang C, He Y, Zou R, Wang L
Journal of oncology 2022;2022:6851026
Journal of oncology 2022;2022:6851026
Dexpramipexole Attenuates White Matter Injury to Facilitate Locomotion and Motor Coordination Recovery via Reducing Ferroptosis after Intracerebral Hemorrhage.
Wang B, Zhang X, Zhong J, Wang S, Zhang C, Li M, Hu Q, Wang S, Chen L, Chen W, Ge H, Feng H
Oxidative medicine and cellular longevity 2022;2022:6160701
Oxidative medicine and cellular longevity 2022;2022:6160701
Extracellular CIRP Upregulates Proinflammatory Cytokine Expression via the NF-kappaB and ERK1/2 Signaling Pathways in Psoriatic Keratinocytes.
Zhang X, Wang S, Wang W, Song L, Feng S, Wang J, Kang T, Yang P, Wang N, Yang P, Bai R, Shao Y, Zheng Y
Mediators of inflammation 2022;2022:5978271
Mediators of inflammation 2022;2022:5978271
Metformin Protects against Spinal Cord Injury and Cell Pyroptosis via AMPK/NLRP3 Inflammasome Pathway.
Yuan Y, Fan X, Guo Z, Zhou Z, Gao W
Analytical cellular pathology (Amsterdam) 2022;2022:3634908
Analytical cellular pathology (Amsterdam) 2022;2022:3634908
Prediction of Prognosis and Recurrence of Bladder Cancer by ECM-Related Genes.
Zhao H, Chen Z, Fang Y, Su M, Xu Y, Wang Z, Gyamfi MA, Zhao J
Journal of immunology research 2022;2022:1793005
Journal of immunology research 2022;2022:1793005
Hyperhomocysteinemia Promotes Cardiac Hypertrophy in Hypertension.
Deng Y, Li Z, An X, Fan R, Wang Y, Li J, Yang X, Liao J, Xia Y
Oxidative medicine and cellular longevity 2022;2022:1486157
Oxidative medicine and cellular longevity 2022;2022:1486157
Repeated Yueju, But Not Fluoxetine, Induced Sustained Antidepressant Activity in a Mouse Model of Chronic Learned Helplessness: Involvement of CaMKII Signaling in the Hippocampus.
Zou Z, Huang J, Yang Q, Zhang Y, Xu B, Wang P, Chen G
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1442578
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1442578
Silencing lncRNA 93358 Inhibits the Apoptosis of Myocardial Cells in Myocardial Infarction Rats by Inducing the Expression of SLC8A1.
Cai J, Wang X, Liao W, Zhong Y, Chen L, Zhang Z
BioMed research international 2022;2022:1138709
BioMed research international 2022;2022:1138709
MiR-3571 modulates the proliferation and migration of vascular smooth muscle cells by targeting claudin 1.
Xie Y, Tan J, Qin Y, Cao Y, Wang Y, Li A, Wang Z, Qiao Z, Yan Z
International journal of medical sciences 2022;19(3):511-524
International journal of medical sciences 2022;19(3):511-524
Caspase-1-mediated extracellular vesicles derived from pyroptotic alveolar macrophages promote inflammation in acute lung injury.
Qin X, Zhou Y, Jia C, Chao Z, Qin H, Liang J, Liu X, Liu Z, Sun T, Yuan Y, Zhang H
International journal of biological sciences 2022;18(4):1521-1538
International journal of biological sciences 2022;18(4):1521-1538
Diprotin A TFA Exerts Neurovascular Protection in Ischemic Cerebral Stroke.
Zhou MY, Zhang YJ, Ding HM, Wu WF, Cai WW, Wang YQ, Geng DQ
Frontiers in neuroscience 2022;16:861059
Frontiers in neuroscience 2022;16:861059
Inhibiting Sphingosine 1-Phosphate Receptor Subtype 3 Attenuates Brain Damage During Ischemia-Reperfusion Injury by Regulating nNOS/NO and Oxidative Stress.
Fan X, Chen H, Xu C, Wang Y, Yin P, Li M, Tang Z, Jiang F, Wei W, Song J, Li G, Zhong D
Frontiers in neuroscience 2022;16:838621
Frontiers in neuroscience 2022;16:838621
BRD7 Stabilizes P53 via Dephosphorylation of MDM2 to Inhibit Tumor Growth in Breast Cancer Harboring Wild-type P53.
Luo Y, Wang X, Niu W, Zhou Y, Li M, Ma J, Yang J, Fan S, Zeng Z, Xiong W, Li X, Li G, Xiao J, Zhou M
Journal of Cancer 2022;13(5):1436-1448
Journal of Cancer 2022;13(5):1436-1448
Qing-Re-Xiao-Zheng-Yi-Qi formula relieves kidney damage and activates mitophagy in diabetic kidney disease.
Wu Q, Yan R, Yang H, Wang Y, Zhang C, Zhang J, Cui Z, Wang Y, Sun W
Frontiers in pharmacology 2022;13:992597
Frontiers in pharmacology 2022;13:992597
Therapeutic effects of shaogan fuzi decoction in rheumatoid arthritis: Network pharmacology and experimental validation.
Shi L, Zhao Y, Feng C, Miao F, Dong L, Wang T, Stalin A, Zhang J, Tu J, Liu K, Sun W, Wu J
Frontiers in pharmacology 2022;13:967164
Frontiers in pharmacology 2022;13:967164
Cuproptosis status affects treatment options about immunotherapy and targeted therapy for patients with kidney renal clear cell carcinoma.
Zhang G, Chen X, Fang J, Tai P, Chen A, Cao K
Frontiers in immunology 2022;13:954440
Frontiers in immunology 2022;13:954440
Optical Visualization of Red-GQDs' Organelles Distribution and Localization in Living Cells.
Hu H, Li P, Qiu J, Zhao M, Kuang M, Zhang Z, Wang D
Frontiers in pharmacology 2022;13:932807
Frontiers in pharmacology 2022;13:932807
ANXA1: An Important Independent Prognostic Factor and Molecular Target in Glioma.
Zhang D, Wang W, Zhou H, Su L, Han X, Zhang X, Han W, Wang Y, Xue X
Frontiers in genetics 2022;13:851505
Frontiers in genetics 2022;13:851505
Oar-miR-432 Regulates Fat Differentiation and Promotes the Expression of BMP2 in Ovine Preadipocytes.
Jin M, Fei X, Li T, Lu Z, Chu M, Di R, He X, Wang X, Wang Y, Yuan Z, Quan K, Wang H, Wei C
Frontiers in genetics 2022;13:844747
Frontiers in genetics 2022;13:844747
Sperm Autoantigenic Protein 17 Predicts the Prognosis and the Immunotherapy Response of Cancers: A Pan-Cancer Analysis.
Tu Z, Peng J, Long X, Li J, Wu L, Huang K, Zhu X
Frontiers in immunology 2022;13:844736
Frontiers in immunology 2022;13:844736
Sleeve Gastrectomy-Induced AMPK Activation Attenuates Diabetic Cardiomyopathy by Maintaining Mitochondrial Homeostasis via NR4A1 Suppression in Rats.
Li S, Dong S, Xu Q, Shi B, Li L, Zhang W, Zhu J, Cheng Y, Zhang G, Zhong M
Frontiers in physiology 2022;13:837798
Frontiers in physiology 2022;13:837798
S1PR3, as a Core Protein Related to Ischemic Stroke, is Involved in the Regulation of Blood-Brain Barrier Damage.
Fan X, Chen H, Xu C, Wang Y, Yin P, Li M, Tang Z, Jiang F, Wei W, Song J, Li G, Zhong D
Frontiers in pharmacology 2022;13:834948
Frontiers in pharmacology 2022;13:834948
Punicalagin Alleviates Psoriasis by Inhibiting NF-κB-Mediated IL-1β Transcription and Caspase-1-Regulated IL-1β Secretion.
Tang L, Li T, Zhang B, Zhang Z, Sun X, Zhu Y, Feng B, Su Z, Yang L, Li H, Liu H, Chen Y, Dai Z, Zheng X, Li M, Li C, Zhao J, Qiu X, Ye S, Liu H, Zheng G, Li B, Lu C
Frontiers in pharmacology 2022;13:817526
Frontiers in pharmacology 2022;13:817526
Avasimibe Alleviates Disruption of the Airway Epithelial Barrier by Suppressing the Wnt/β-Catenin Signaling Pathway.
Zhou Z, Liang S, Zhou Z, Liu J, Meng X, Zou F, Yu C, Cai S
Frontiers in pharmacology 2022;13:795934
Frontiers in pharmacology 2022;13:795934
Identification of super-enhancer-driven peptidyl arginine deiminases as potential biomarkers and therapeutic targets for osimertinib-resistant non-small cell lung cancer.
Li H, Muhetaer G, Xie Y, Yao K, Ma Q, Guan H, Xing S, Huang X, Zhou J
Frontiers in pharmacology 2022;13:1071365
Frontiers in pharmacology 2022;13:1071365
Small RNA perspective of physical exercise-related improvement of male reproductive dysfunction due to obesity.
Lin T, Zhang S, Zhou Y, Wu L, Liu X, Huang H
Frontiers in endocrinology 2022;13:1038449
Frontiers in endocrinology 2022;13:1038449
Berberine prevents lethal EV71 neurological infection in newborn mice.
Cui G, Wang H, Yang C, Zhou X, Wang J, Wang T, Ma T
Frontiers in pharmacology 2022;13:1027566
Frontiers in pharmacology 2022;13:1027566
X-box binding protein 1: A new metabolic mediator and drug target of metformin?
Lou K, Sun P, Zhang C, Jiang Q, Pang S
Frontiers in pharmacology 2022;13:1013218
Frontiers in pharmacology 2022;13:1013218
Prrx1 promotes resistance to temozolomide by upregulating ABCC1 and inducing vasculogenic mimicry in glioma.
Chen Z, Zhang Y, Chen Y, Lin W, Zhang Y, Cai G, Sun X, Zheng K, He J, Ai T, Wang J, Zhao L, Ke Y
American journal of cancer research 2022;12(8):3892-3912
American journal of cancer research 2022;12(8):3892-3912
Interleukin 33-mediated inhibition of A-type K(+) channels induces sensory neuronal hyperexcitability and nociceptive behaviors in mice.
Wang Y, Wang X, Qi R, Lu Y, Tao Y, Jiang D, Sun Y, Jiang X, Liu C, Zhang Y, Tao J
Theranostics 2022;12(5):2232-2247
Theranostics 2022;12(5):2232-2247
The PROTAC selectively degrading Bcl-x(L) represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while sparing bone growth.
Zhang S, Chen Y, Xu Z, Yang J, Sun R, Wang J, Sun Y, Jiang B, Yang X, Tan W
Theranostics 2022;12(17):7476-7490
Theranostics 2022;12(17):7476-7490
A novel HCC prognosis predictor PDSS1 affects the cell cycle through the STAT3 signaling pathway in HCC.
Rao Z, Li H, Yao W, Wang Q, Ma B, Xue D, Meng X
Frontiers in oncology 2022;12:927468
Frontiers in oncology 2022;12:927468
The Synergistic Cytotoxic Effects of GW5074 and Sorafenib by Impacting Mitochondrial Functions in Human Colorectal Cancer Cell Lines.
Hu JM, Chang YL, Hsieh CC, Huang SM
Frontiers in oncology 2022;12:925653
Frontiers in oncology 2022;12:925653
Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6.
Wang H, Zhao S, Liu Y, Sun F, Huang X, Wu T
Frontiers in oncology 2022;12:898047
Frontiers in oncology 2022;12:898047
AQP5 Is a Novel Prognostic Biomarker in Pancreatic Adenocarcinoma.
Chen G, Song H, Yang Z, Du T, Zheng Y, Lu Z, Zhang K, Wei D
Frontiers in oncology 2022;12:890193
Frontiers in oncology 2022;12:890193
Transient Receptor Potential Cation Channel Subfamily V Member 1 Expression Promotes Chemoresistance in Non-Small-Cell Lung Cancer.
Li L, Chen C, Xiang Q, Fan S, Xiao T, Chen Y, Zheng D
Frontiers in oncology 2022;12:773654
Frontiers in oncology 2022;12:773654
Label-free LC-MS/MS proteomics analyses reveal CLIC1 as a predictive biomarker for bladder cancer staging and prognosis.
Wang W, Huang G, Lin H, Ren L, Fu L, Mao X
Frontiers in oncology 2022;12:1102392
Frontiers in oncology 2022;12:1102392
HIF-1/2α-Activated RNF146 Enhances the Proliferation and Glycolysis of Hepatocellular Carcinoma Cells via the PTEN/AKT/mTOR Pathway.
Shen G, Wang H, Zhu N, Lu Q, Liu J, Xu Q, Huang D
Frontiers in cell and developmental biology 2022;10:893888
Frontiers in cell and developmental biology 2022;10:893888
Chicken ISG12(2) attenuates Newcastle disease virus and enhances the efficiency of Newcastle disease vaccine via activating immune pathways.
Liu H, Tian J, Lu K, Li Y, Guan Z, Cao X, Li X, Chang Z, Wang X, Sa X, Yang Z
Transboundary and emerging diseases 2022 Sep;69(5):2634-2648
Transboundary and emerging diseases 2022 Sep;69(5):2634-2648
Nav1.8 in keratinocytes contributes to ROS-mediated inflammation in inflammatory skin diseases.
Zhang Y, Li Y, Zhou L, Yuan X, Wang Y, Deng Q, Deng Z, Xu S, Wang Q, Xie H, Li J
Redox biology 2022 Sep;55:102427
Redox biology 2022 Sep;55:102427
Silica nanoparticle exposure inhibits surfactant protein A and B in A549 cells through ROS-mediated JNK/c-Jun signaling pathway.
Yang X, Yang P, Zhang J, Yang Y, Xiong M, Shi F, Li N, Jin Y
Environmental toxicology 2022 Sep;37(9):2291-2301
Environmental toxicology 2022 Sep;37(9):2291-2301
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Zhu C, Tian M, Liu N, Ma L, Lan X, Yang J, Du J, Ma H, Li Y, Zheng P, Yu J, Peng X
Phytotherapy research : PTR 2022 Sep;36(9):3644-3661
Phytotherapy research : PTR 2022 Sep;36(9):3644-3661
Vagus nerve stimulation promotes the M1-to-M2 transition via inhibition of TLR4/NF-κB in microglial to rescue the reperfusion injury.
Zhang L, Zhang X, Liu Y, Wang S, Jia G
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Sep;31(9):106596
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Sep;31(9):106596
UFL1 alleviates ER stress and apoptosis stimulated by LPS via blocking the ferroptosis pathway in human granulosa-like cells.
Li J, Tang X, Tu X, Jin Z, Dong H, Yang Q, Yao T, Pan Z
Cell stress & chaperones 2022 Sep;27(5):485-497
Cell stress & chaperones 2022 Sep;27(5):485-497
Elevated phosphorylation of EGFR in NSCLC due to mutations in PTPRH.
Swiatnicki MR, Rennhack JP, Ortiz MMO, Hollern DP, Perry AV, Kubiak R, Riveria Riveria SM, O'Reilly S, Andrechek ER
PLoS genetics 2022 Sep;18(9):e1010362
PLoS genetics 2022 Sep;18(9):e1010362
Deficiency of proline/serine-rich coiled-coil protein 1 (PSRC1) accelerates trimethylamine N-oxide-induced atherosclerosis in ApoE(-/-) mice.
Luo T, Liu D, Guo Z, Chen P, Guo Z, Ou C, Chen M
Journal of molecular and cellular cardiology 2022 Sep;170:60-74
Journal of molecular and cellular cardiology 2022 Sep;170:60-74
Phosphorylation of Ser82 on IRF3 acts as negative-feedback regulation of IRF3-dependent innate immunity.
Cheng Q, Yuan L, Guo J, Guo D, Liu X, Li S
The international journal of biochemistry & cell biology 2022 Sep;150:106275
The international journal of biochemistry & cell biology 2022 Sep;150:106275
Gut microbiota-derived metabolites contribute negatively to hindgut barrier function development at the early weaning goat model.
Zhang K, Xu Y, Yang Y, Guo M, Zhang T, Zong B, Huang S, Suo L, Ma B, Wang X, Wu Y, Brugger D, Chen Y
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Sep;10:111-123
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Sep;10:111-123
Metabolic Syndrome Ameliorated by 4-Methylesculetin by Reducing Hepatic Lipid Accumulation.
Li L, Zhu G, Fu G, Zha W, Li H
International journal of molecular sciences 2022 Sep 9;23(18)
International journal of molecular sciences 2022 Sep 9;23(18)
Proteomic and Biochemical Approaches Elucidate the Role of Millimeter-Wave Irradiation in Wheat Growth under Flooding Stress.
Komatsu S, Tsutsui Y, Furuya T, Yamaguchi H, Hitachi K, Tsuchida K, Tani M
International journal of molecular sciences 2022 Sep 8;23(18)
International journal of molecular sciences 2022 Sep 8;23(18)
Acid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis.
Xiao J, Zeng W, Zhang P, Zhou Y, Fang Q
Molecular medicine (Cambridge, Mass.) 2022 Sep 6;28(1):106
Molecular medicine (Cambridge, Mass.) 2022 Sep 6;28(1):106
Supramolecular Hydrogel-Wrapped Gingival Mesenchymal Stem Cells in Cutaneous Radiation Injury.
Nie S, Ren C, Liang X, Cai H, Sun H, Liu F, Ji K, Wang Y, Liu Q
Cells 2022 Sep 30;11(19)
Cells 2022 Sep 30;11(19)
Proteomic characterization of gastric cancer response to chemotherapy and targeted therapy reveals new therapeutic strategies.
Li Y, Xu C, Wang B, Xu F, Ma F, Qu Y, Jiang D, Li K, Feng J, Tian S, Wu X, Wang Y, Liu Y, Qin Z, Liu Y, Qin J, Song Q, Zhang X, Sujie A, Huang J, Liu T, Shen K, Zhao JY, Hou Y, Ding C
Nature communications 2022 Sep 29;13(1):5723
Nature communications 2022 Sep 29;13(1):5723
Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model.
Ji J, Li S, Jiang Z, Yu J, Sun Y, Cai Z, Dong Y, Sun X
International journal of molecular sciences 2022 Sep 16;23(18)
International journal of molecular sciences 2022 Sep 16;23(18)
Role of PARP-1 in Human Cytomegalovirus Infection and Functional Partners Encoded by This Virus.
Zhang W, Guo J, Chen Q
Viruses 2022 Sep 15;14(9)
Viruses 2022 Sep 15;14(9)
MARCH1 promotes the growth and maintaining of stem cell-like characteristics of gastric cancer cells by activating the Wnt/β-catenin signaling pathway.
Liang W, Zhang T, Huo J, Yang J
Tissue & cell 2022 Oct;78:101895
Tissue & cell 2022 Oct;78:101895
LncRNA ALKBH3-AS1 enhances ALKBH3 mRNA stability to promote hepatocellular carcinoma cell proliferation and invasion.
Lu Q, Wang H, Lei X, Ma Q, Zhao J, Sun W, Guo C, Huang D, Xu Q
Journal of cellular and molecular medicine 2022 Oct;26(20):5292-5302
Journal of cellular and molecular medicine 2022 Oct;26(20):5292-5302
Proteome-wide analysis of the hippocampus in adolescent male mice with learning and memory impairment caused by chronic ethanol exposure.
Liu D, Liu S, Li J, Liu X, Wu X, Peng Y, Shen Q
Neurobiology of learning and memory 2022 Oct;194:107661
Neurobiology of learning and memory 2022 Oct;194:107661
The phytochemical constituents and protective effect of Fritillaria hupehensis on acute lung injury.
Xiang ML, Zhao YL, Liu YY, Yan XJ, Chen S, Luo XD
Fitoterapia 2022 Oct;162:105283
Fitoterapia 2022 Oct;162:105283
Reticulocalbin3: A Ca(2+) homeostasis regulator that promotes esophageal squamous cell carcinoma progression and cisplatin resistance.
Cai R, Wang P, Zhao X, Lu X, Deng R, Wang X, Hong C, Lin J
Cancer science 2022 Oct;113(10):3593-3607
Cancer science 2022 Oct;113(10):3593-3607
Targeting PERK mediated endoplasmic reticulum stress attenuates neuroinflammation and alleviates lipopolysaccharide-induced depressive-like behavior in male mice.
Xu XF, Shi MM, Luo MY, Liu DD, Guo DM, Ling C, Zhong XL, Xu Y, Cao WY
International immunopharmacology 2022 Oct;111:109092
International immunopharmacology 2022 Oct;111:109092
Local Application of Krill Oil Accelerates the Healing of Artificially Created Wounds in Diabetic Mice.
Hao W, Meng H, Li H, Zheng Y, Song C, Jiang Z, Bai X, Zhang Z, Du L, Liu P, Wu H
Nutrients 2022 Oct 5;14(19)
Nutrients 2022 Oct 5;14(19)
Hepatic inactivation of murine Surf4 results in marked reduction in plasma cholesterol.
Tang VT, McCormick J, Xu B, Wang Y, Fang H, Wang X, Siemieniak D, Khoriaty R, Emmer BT, Chen XW, Ginsburg D
eLife 2022 Oct 4;11
eLife 2022 Oct 4;11
Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood-Milk Barrier.
Zou Y, Wang X, Xu J, Wang S, Li S, Zhu Y, Wang J
International journal of molecular sciences 2022 Oct 31;23(21)
International journal of molecular sciences 2022 Oct 31;23(21)
Knockdown of CLAUDIN-6 Inhibited Apoptosis and Induced Proliferation of Bovine Cumulus Cells.
Wang W, Zou H, Chen N, Tian Y, Hao H, Pang Y, Zhao X, Zhu H, Yu D, Du W
International journal of molecular sciences 2022 Oct 30;23(21)
International journal of molecular sciences 2022 Oct 30;23(21)
Hypoxia-Regulated lncRNA USP2-AS1 Drives Head and Neck Squamous Cell Carcinoma Progression.
Tang J, Wu Z, Wang X, Hou Y, Bai Y, Tian Y
Cells 2022 Oct 28;11(21)
Cells 2022 Oct 28;11(21)
Angiotensin-converting enzyme 2 identifies immuno-hot tumors suggesting angiotensin-(1-7) as a sensitizer for chemotherapy and immunotherapy in breast cancer.
Mei J, Cai Y, Xu R, Yu X, Han X, Weng M, Chen L, Ma T, Gao T, Gao F, Xia T, Zhu Y, Zhang Y
Biological procedures online 2022 Oct 25;24(1):15
Biological procedures online 2022 Oct 25;24(1):15
Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis.
Deng R, Lu X, Hong C, Cai R, Wang P, Xiong L, Wang X, Chen Q, Lin J
Journal of translational medicine 2022 Oct 23;20(1):485
Journal of translational medicine 2022 Oct 23;20(1):485
TRPM8 contributes to sex dimorphism by promoting recovery of normal sensitivity in a mouse model of chronic migraine.
Alarcón-Alarcón D, Cabañero D, de Andrés-López J, Nikolaeva-Koleva M, Giorgi S, Fernández-Ballester G, Fernández-Carvajal A, Ferrer-Montiel A
Nature communications 2022 Oct 22;13(1):6304
Nature communications 2022 Oct 22;13(1):6304
The role of E3 ubiquitin ligase WWP2 and the regulation of PARP1 by ubiquitinated degradation in acute lymphoblastic leukemia.
Lu X, Huang X, Xu H, Lu S, You S, Xu J, Zhan Q, Dong C, Zhang N, Zhang Y, Cao L, Zhang X, Zhang N, Zhang L
Cell death discovery 2022 Oct 18;8(1):421
Cell death discovery 2022 Oct 18;8(1):421
Kaempferol prevents angiogenesis of rat intestinal microvascular endothelial cells induced by LPS and TNF-α via inhibiting VEGF/Akt/p38 signaling pathways and maintaining gut-vascular barrier integrity.
Yu R, Zhong J, Zhou Q, Ren W, Liu Z, Bian Y
Chemico-biological interactions 2022 Oct 1;366:110135
Chemico-biological interactions 2022 Oct 1;366:110135
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
Liu F, Wang Y, Chen L, Bello BK, Zhang T, Yang H, Li X, Pan E, Feng H, Dong J
Ecotoxicology and environmental safety 2022 Oct 1;244:114081
Ecotoxicology and environmental safety 2022 Oct 1;244:114081
Synthetic Retinoid Kills Drug-Resistant Cancer Stem Cells via Inducing RARγ-Translocation-Mediated Tension Reduction and Chromatin Decondensation.
Zhang Y, Dong Q, An Q, Zhang C, Mohagheghian E, Niu B, Qi F, Wei F, Chen S, Chen X, Wang A, Cao X, Wang N, Chen J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Nov;9(31):e2203173
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Nov;9(31):e2203173
Knockdown of TTC9 inhibits the proliferation, migration and invasion, but induces the apoptosis of lung adenocarcinoma cells.
Huang X, Jiang L, Wen Z, Yuan M, Zhong Y
Heliyon 2022 Nov;8(11):e11254
Heliyon 2022 Nov;8(11):e11254
Overexpression of PYGO1 promotes early cardiac lineage development in human umbilical cord mesenchymal stromal/stem cells by activating the Wnt/β-catenin pathway.
Shen J, Wu X, Zhu P, Zhuang J, Qin B, Sun F, Yuan W, Fan X, Jiang Z, Li F, Li Y, Wang Y, Zhao M
Human cell 2022 Nov;35(6):1722-1735
Human cell 2022 Nov;35(6):1722-1735
Homozygous missense mutation in CCDC155 disrupts the transmembrane distribution of CCDC155 and SUN1, resulting in non-obstructive azoospermia and premature ovarian insufficiency in humans.
Wu H, Zhang X, Hua R, Li Y, Cheng L, Li K, Liu Y, Gao Y, Shen Q, Wang G, Lv M, Xu Y, He X, Cao Y, Liu M
Human genetics 2022 Nov;141(11):1795-1809
Human genetics 2022 Nov;141(11):1795-1809
Hydrogen improves exercise endurance in rats by promoting mitochondrial biogenesis.
Luo M, Lu J, Li C, Wen B, Chu W, Dang X, Zhang Y, An G, Wang J, Fan R, Chen X
Genomics 2022 Nov;114(6):110523
Genomics 2022 Nov;114(6):110523
Hyperglycemia promotes myocardial dysfunction via the ERS-MAPK10 signaling pathway in db/db mice.
Deng YW, Liu F, Li ZT, Gao JH, Zhao Y, Yang XL, Xia YL
Laboratory investigation; a journal of technical methods and pathology 2022 Nov;102(11):1192-1202
Laboratory investigation; a journal of technical methods and pathology 2022 Nov;102(11):1192-1202
Regulation of cohesin-mediated chromosome folding by PDS5 in mammals.
Yu D, Chen G, Wang Y, Wang Y, Lin R, Liu N, Zhu P, Liu H, Hu T, Feng R, Feng H, Lan F, Cai J, Chen H
EMBO reports 2022 Nov 7;23(11):e54853
EMBO reports 2022 Nov 7;23(11):e54853
Discovery of a novel Pleuromutilin derivative as anti-IPF lead compound via high-throughput assay.
Zhang K, Liang J, Wang N, Li N, Jiang Y, Li X, Yang C, Zhou H, Yang G
European journal of medicinal chemistry 2022 Nov 5;241:114643
European journal of medicinal chemistry 2022 Nov 5;241:114643
Functional Attenuation of UCP1 as the Potential Mechanism for a Thickened Blubber Layer in Cetaceans.
Zhou M, Wu T, Chen Y, Xu S, Yang G
Molecular biology and evolution 2022 Nov 3;39(11)
Molecular biology and evolution 2022 Nov 3;39(11)
Trichostatin D as a Novel KLF2 Activator Attenuates TNFα-Induced Endothelial Inflammation.
Lei L, Chen M, Wang C, Jiang X, Li Y, Wang W, Li S, Zhao L, Sheng R, Han J, Zhang Y, Chen Y, Yan B, Wu Y, Yu L, Si S, Xu Y
International journal of molecular sciences 2022 Nov 3;23(21)
International journal of molecular sciences 2022 Nov 3;23(21)
Differential requirements of IQUB for the assembly of radial spoke 1 and the motility of mouse cilia and flagella.
Zhang X, Xiao Z, Zhang J, Xu C, Liu S, Cheng L, Zhou S, Zhao S, Zhang Y, Wu J, Wang Y, Liu M
Cell reports 2022 Nov 22;41(8):111683
Cell reports 2022 Nov 22;41(8):111683
Hydrogen Sulfide Regulates SERCA2a Ubiquitylation via Muscle RING Finger-1 S-Sulfhydration to Affect Cardiac Contractility in db/db Mice.
Peng S, Zhao D, Li Q, Wang M, Zhang S, Pang K, Huang J, Lu F, Chen H, Zhang W
Cells 2022 Nov 2;11(21)
Cells 2022 Nov 2;11(21)
mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters.
Liu Y, Azizian NG, Sullivan DK, Li Y
Nature communications 2022 Nov 17;13(1):7047
Nature communications 2022 Nov 17;13(1):7047
NAP1L5 targeting combined with MYH9 Inhibit HCC progression through PI3K/AKT/mTOR signaling pathway.
Zhao R, Ge Y, Gong Y, Li B, Xiao B, Zuo S
Aging 2022 Nov 11;14(22):9000-9019
Aging 2022 Nov 11;14(22):9000-9019
Inhibitory effect of tanshinone IIA, resveratrol and silibinin on enterovirus 68 production through inhibiting ATM and DNA-PK pathway.
Su Y, Wu T, Yu XY, Huo WB, Wang SH, Huan C, Liu YM, Liu JM, Cui MN, Li XH, Yu JH
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153977
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153977
cGAS-STING mediates cytoplasmic mitochondrial-DNA-induced inflammatory signal transduction during accelerated senescence of pancreatic β-cells induced by metabolic stress.
Hu H, Zhao R, He Q, Cui C, Song J, Guo X, Zang N, Yang M, Zou Y, Yang J, Li J, Wang L, Xia L, Wang L, He F, Hou X, Yan F, Chen L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 May;36(5):e22266
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 May;36(5):e22266
SMAD4 Inhibits Granulosa Cell Apoptosis via the miR-183-96-182 Cluster and FoxO1 Axis.
Yao W, Wang S, Du X, Lin C, Zhang J, Pan Z, Li Q
Reproductive sciences (Thousand Oaks, Calif.) 2022 May;29(5):1577-1585
Reproductive sciences (Thousand Oaks, Calif.) 2022 May;29(5):1577-1585
Type IIB PKA is highly expressed in β cells and controls cell proliferation via regulating Cyclin D1 expression.
Jiang Y, Zhu L, Wu D, Ni Y, Huang C, Ye H, Yang Y, Liu R, Li Y
The FEBS journal 2022 May;289(10):2865-2876
The FEBS journal 2022 May;289(10):2865-2876
The roles of grouper TAK1 in regulating the infection of Singapore grouper iridovirus.
Zhang L, Kang S, Chen H, Liao J, Sun M, Wu S, Xu Z, Xu L, Zhang X, Qin Q, Wei J
Fish & shellfish immunology 2022 May;124:164-173
Fish & shellfish immunology 2022 May;124:164-173
Ubiquitin-like modifier 1 ligating enzyme 1 relieves cisplatin-induced premature ovarian failure by reducing endoplasmic reticulum stress in granulosa cells.
Tang X, Dong H, Fang Z, Li J, Yang Q, Yao T, Pan Z
Reproductive biology and endocrinology : RB&E 2022 May 24;20(1):84
Reproductive biology and endocrinology : RB&E 2022 May 24;20(1):84
MiR-135a-5p suppresses trophoblast proliferative, migratory, invasive, and angiogenic activity in the context of unexplained spontaneous abortion.
Lu Y, Zhang X, Li X, Deng L, Wei C, Yang D, Tan X, Pan W, Pang L
Reproductive biology and endocrinology : RB&E 2022 May 24;20(1):82
Reproductive biology and endocrinology : RB&E 2022 May 24;20(1):82
Aberrant translation regulated by METTL1/WDR4-mediated tRNA N7-methylguanosine modification drives head and neck squamous cell carcinoma progression.
Chen J, Li K, Chen J, Wang X, Ling R, Cheng M, Chen Z, Chen F, He Q, Li S, Zhang C, Jiang Y, Chen Q, Wang A, Chen D
Cancer communications (London, England) 2022 Mar;42(3):223-244
Cancer communications (London, England) 2022 Mar;42(3):223-244
Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury.
Lin F, Chen W, Zhou J, Zhu J, Yao Q, Feng B, Feng X, Shi X, Pan Q, Yu J, Li L, Cao H
Cell death & disease 2022 Mar 26;13(3):271
Cell death & disease 2022 Mar 26;13(3):271
p62 Promotes the Mitochondrial Localization of p53 through Its UBA Domain and Participates in Regulating the Sensitivity of Ovarian Cancer Cells to Cisplatin.
Kong Q, Yan X, Cheng M, Jiang X, Xu L, Shen L, Yu H, Sun L
International journal of molecular sciences 2022 Mar 18;23(6)
International journal of molecular sciences 2022 Mar 18;23(6)
Iron metabolism protein transferrin receptor 1 involves in cervical cancer progression by affecting gene expression and alternative splicing in HeLa cells.
Huang N, Wei Y, Cheng Y, Wang X, Wang Q, Chen D, Li W
Genes & genomics 2022 Jun;44(6):637-650
Genes & genomics 2022 Jun;44(6):637-650
Effects of ALA-PDT on the macrophages in wound healing and its related mechanisms in vivo and in vitro.
Li L, Yang Y, Yang Z, Zheng M, Luo G, He W, Yin R
Photodiagnosis and photodynamic therapy 2022 Jun;38:102816
Photodiagnosis and photodynamic therapy 2022 Jun;38:102816
Rutin-activated adipose tissue thermogenesis is correlated with increased intestinal short-chain fatty acid levels.
Cheng L, Shi L, He C, Wang C, Lv Y, Li H, An Y, Dai H, Duan Y, Zhang H, Huang Y, Fu W, Meng Y, Zhao B
Phytotherapy research : PTR 2022 Jun;36(6):2495-2510
Phytotherapy research : PTR 2022 Jun;36(6):2495-2510
Dexmedetomidine attenuates perioperative neurocognitive disorders by suppressing hippocampal neuroinflammation and HMGB1/RAGE/NF-κB signaling pathway.
Wang J, Xin Y, Chu T, Liu C, Xu A
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113006
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113006
NPM1 promotes cell proliferation by targeting PRDX6 in colorectal cancer.
Wang D, Li Y, Liu Y, Cheng S, Liu F, Zuo R, Ding C, Shi S, Liu G
The international journal of biochemistry & cell biology 2022 Jun;147:106233
The international journal of biochemistry & cell biology 2022 Jun;147:106233
Deacetylation of Caveolin-1 by Sirt6 induces autophagy and retards high glucose-stimulated LDL transcytosis and atherosclerosis formation.
Zhao Y, Jia X, Yang X, Bai X, Lu Y, Zhu L, Cheng W, Shu M, Zhu Y, Du X, Wang L, Shu Y, Song Y, Jin S
Metabolism: clinical and experimental 2022 Jun;131:155162
Metabolism: clinical and experimental 2022 Jun;131:155162
Heart-targeted amelioration of sepsis-induced myocardial dysfunction by microenvironment responsive nitric oxide nanogenerators in situ.
Ouyang M, Ouyang X, Peng Z, Liu M, Xu G, Zou Z, Zhang M, Shang Q
Journal of nanobiotechnology 2022 Jun 7;20(1):263
Journal of nanobiotechnology 2022 Jun 7;20(1):263
Sesamin Activates Skeletal Muscle FNDC5 Expression and Increases Irisin Secretion via the SIRT1 Signaling Pathway.
Kou G, Li P, Shi Y, Traore SS, Shi X, Amoah AN, Cui Z, Lyu Q
Journal of agricultural and food chemistry 2022 Jun 29;70(25):7704-7715
Journal of agricultural and food chemistry 2022 Jun 29;70(25):7704-7715
The mechanism of dioscin preventing lung cancer based on network pharmacology and experimental validation.
Xi P, Niu Y, Zhang Y, Li W, Gao F, Gu W, Kui F, Liu Z, Lu L, Du G
Journal of ethnopharmacology 2022 Jun 28;292:115138
Journal of ethnopharmacology 2022 Jun 28;292:115138
circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop.
Li X, Wang J, Lin W, Yuan Q, Lu Y, Wang H, Chen Y, Chen L, Dai P, Long H, Li X
Molecular cancer 2022 Jun 23;21(1):135
Molecular cancer 2022 Jun 23;21(1):135
Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached.
Wilcock DJ, Badrock AP, Wong CW, Owen R, Guerin M, Southam AD, Johnston H, Telfer BA, Fullwood P, Watson J, Ferguson H, Ferguson J, Lloyd GR, Jankevics A, Dunn WB, Wellbrock C, Lorigan P, Ceol C, Francavilla C, Smith MP, Hurlstone AFL
Cell reports 2022 Jun 21;39(12):110995
Cell reports 2022 Jun 21;39(12):110995
Transcriptome study digs out BMP2 involved in adipogenesis in sheep tails.
Jin M, Fei X, Li T, Lu Z, Chu M, Di R, He X, Wang X, Wei C
BMC genomics 2022 Jun 21;23(1):457
BMC genomics 2022 Jun 21;23(1):457
JNK and Jag1/Notch2 co-regulate CXCL16 to facilitate cypermethrin-induced kidney damage.
Liu C, Wu M, Qu J, Huang X, Zeng Q, Ha M
Ecotoxicology and environmental safety 2022 Jun 15;238:113582
Ecotoxicology and environmental safety 2022 Jun 15;238:113582
Difenoconazole causes spleen tissue damage and immune dysfunction of carp through oxidative stress and apoptosis.
Liu F, Li X, Bello BK, Zhang T, Yang H, Wang K, Dong J
Ecotoxicology and environmental safety 2022 Jun 1;237:113563
Ecotoxicology and environmental safety 2022 Jun 1;237:113563
Chronic exposure of alcohol triggers microglia-mediated synaptic elimination inducing cognitive impairment.
Lan L, Wang H, Zhang X, Shen Q, Li X, He L, Rong X, Peng J, Mo J, Peng Y
Experimental neurology 2022 Jul;353:114061
Experimental neurology 2022 Jul;353:114061
Lysyl oxidase-like 2 inhibitor rescues D-galactose-induced skeletal muscle fibrosis.
Wu Y, Wu Y, Yang Y, Yu J, Wu J, Liao Z, Guo A, Sun Y, Zhao Y, Chen J, Xiao Q
Aging cell 2022 Jul;21(7):e13659
Aging cell 2022 Jul;21(7):e13659
The neuroprotective effects of GPR55 against hippocampal neuroinflammation and impaired adult neurogenesis in CSDS mice.
Shen SY, Yu R, Li W, Liang LF, Han QQ, Huang HJ, Li B, Xu SF, Wu GC, Zhang YQ, Yu J
Neurobiology of disease 2022 Jul;169:105743
Neurobiology of disease 2022 Jul;169:105743
Time series RNA-seq analysis identifies MAPK10 as a critical gene in diabetes mellitus-induced atrial fibrillation in mice.
Liu F, Deng Y, Zhao Y, Li Z, Gao J, Zhang Y, Yang X, Liu Y, Xia Y
Journal of molecular and cellular cardiology 2022 Jul;168:70-82
Journal of molecular and cellular cardiology 2022 Jul;168:70-82
Cortistatin attenuates titanium particle-induced osteolysis through regulation of TNFR1-ROS-caspase-3 signaling in osteoblasts.
Cao J, Ma X, Liu L, Zhang G, Wu Y, Fu Y, Gong A, Yang Z, Zhao Y, Zhang L, Li Y
Annals of the New York Academy of Sciences 2022 Jul;1513(1):140-152
Annals of the New York Academy of Sciences 2022 Jul;1513(1):140-152
Morphological and Proteomic Analyses of Soybean Seedling Interaction Mechanism Affected by Fiber Crosslinked with Zinc-Oxide Nanoparticles.
Komatsu S, Murata K, Yakeishi S, Shimada K, Yamaguchi H, Hitachi K, Tsuchida K, Obi R, Akita S, Fukuda R
International journal of molecular sciences 2022 Jul 3;23(13)
International journal of molecular sciences 2022 Jul 3;23(13)
Discovery of Novel Phosphoinositide-3-Kinase α Inhibitors with High Selectivity, Excellent Bioavailability, and Long-Acting Efficacy for Gastric Cancer.
Hou Y, Zhang F, Min W, Yuan K, Kuang W, Wang X, Zhu Y, Sun C, Xia F, Wang Y, Zhang H, Wang L, Yang P
Journal of medicinal chemistry 2022 Jul 28;65(14):9873-9892
Journal of medicinal chemistry 2022 Jul 28;65(14):9873-9892
Dysregulation of SIRT3 SUMOylation Confers AML Chemoresistance via Controlling HES1-Dependent Fatty Acid Oxidation.
Zhang Y, Shen Y, Wei W, Wang W, Jiang D, Ren Y, Peng Z, Fan Q, Cheng J, Ma J
International journal of molecular sciences 2022 Jul 27;23(15)
International journal of molecular sciences 2022 Jul 27;23(15)
Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage.
Zhou H, Shen X, Yan C, Xiong W, Ma Z, Tan Z, Wang J, Li Y, Liu J, Duan A, Liu F
Stem cell research & therapy 2022 Jul 16;13(1):322
Stem cell research & therapy 2022 Jul 16;13(1):322
Quantitative proteomics analysis to assess protein expression levels in the ovaries of pubescent goats.
Qin P, Ye J, Gong X, Yan X, Lin M, Lin T, Liu T, Li H, Wang X, Zhu Y, Li X, Liu Y, Li Y, Ling Y, Zhang X, Fang F
BMC genomics 2022 Jul 13;23(1):507
BMC genomics 2022 Jul 13;23(1):507
Increased m6A-RNA methylation and FTO suppression is associated with myocardial inflammation and dysfunction during endotoxemia in mice.
Dubey PK, Patil M, Singh S, Dubey S, Ahuja P, Verma SK, Krishnamurthy P
Molecular and cellular biochemistry 2022 Jan;477(1):129-141
Molecular and cellular biochemistry 2022 Jan;477(1):129-141
BCAA-BCKA axis regulates WAT browning through acetylation of PRDM16.
Ma QX, Zhu WY, Lu XC, Jiang D, Xu F, Li JT, Zhang L, Wu YL, Chen ZJ, Yin M, Huang HY, Lei QY
Nature metabolism 2022 Jan;4(1):106-122
Nature metabolism 2022 Jan;4(1):106-122
Bioglass promotes wound healing by inhibiting endothelial cell pyroptosis through regulation of the connexin 43/reactive oxygen species (ROS) signaling pathway.
Zhang K, Chai B, Ji H, Chen L, Ma Y, Zhu L, Xu J, Wu Y, Lan Y, Li H, Feng Z, Xiao J, Zhang H, Xu K
Laboratory investigation; a journal of technical methods and pathology 2022 Jan;102(1):90-101
Laboratory investigation; a journal of technical methods and pathology 2022 Jan;102(1):90-101
A homozygous loss-of-function mutation in FBXO43 causes human non-obstructive azoospermia.
Wu H, Zhang X, Shen Q, Liu Y, Gao Y, Wang G, Lv M, Hua R, Xu Y, Zhou P, Wei Z, Tao F, He X, Cao Y, Liu M
Clinical genetics 2022 Jan;101(1):55-64
Clinical genetics 2022 Jan;101(1):55-64
CHMFL-BMX-078, a BMX inhibitor, overcomes the resistance of melanoma to vemurafenib via inhibiting AKT pathway.
Jiang S, Jiang T, Huang H, Chen X, Li L, Wang Z, Fei J, Liu C, Liu Z, Cheng Y
Chemico-biological interactions 2022 Jan 5;351:109747
Chemico-biological interactions 2022 Jan 5;351:109747
An efficient strategy for digging protein-protein interactions for rational drug design - A case study with HIF-1α/VHL.
Xue X, Kang JB, Yang X, Li N, Chang L, Ji J, Meng XK, Zhang HQ, Zhong Y, Yu SP, Wu WY, Wang XL, Li NG, Sun SL
European journal of medicinal chemistry 2022 Jan 5;227:113871
European journal of medicinal chemistry 2022 Jan 5;227:113871
Qingwei San treats oral ulcer subjected to stomach heat syndrome in db/db mice by targeting TLR4/MyD88/NF-κB pathway.
Shi L, An Y, Cheng L, Li Y, Li H, Wang C, Lv Y, Duan Y, Dai H, He C, Zhang H, Huang Y, Fu W, Wang S, Zhao B, Wang Y, Zhao Y
Chinese medicine 2022 Jan 4;17(1):1
Chinese medicine 2022 Jan 4;17(1):1
ID2 inhibits innate antiviral immunity by blocking TBK1- and IKKε-induced activation of IRF3.
Yu C, Wang B, Zhu Y, Zhang C, Ren L, Lei X, Xiang Z, Zhou Z, Huang H, Wang J, Zhao Z
Science signaling 2022 Jan 4;15(715):eabh0068
Science signaling 2022 Jan 4;15(715):eabh0068
Increased expression of osteopontin in subchondral bone promotes bone turnover and remodeling, and accelerates the progression of OA in a mouse model.
Lin C, Chen Z, Guo D, Zhou L, Lin S, Li C, Li S, Wang X, Lin B, Ding Y
Aging 2022 Jan 4;14(1):253-271
Aging 2022 Jan 4;14(1):253-271
The bibenzyl derivatives of Dendrobium officinale prevent UV-B irradiation induced photoaging via SIRT3.
Chen DK, Shao HY, Yang L, Hu JM
Natural products and bioprospecting 2022 Jan 27;12(1):1
Natural products and bioprospecting 2022 Jan 27;12(1):1
Sodium hydrosulfide reverses β(2)-microglobulin-induced depressive-like behaviors of male Sprague-Dawley rats: Involving improvement of synaptic plasticity and enhancement of Warburg effect in hippocampus.
Yang SQ, Tang YY, Zeng D, Tian Q, Wei HJ, Wang CY, Zhang P, Chen YJ, Zou W, Tang XQ
Behavioural brain research 2022 Jan 24;417:113562
Behavioural brain research 2022 Jan 24;417:113562
Nrf2 loss of function exacerbates endoplasmic reticulum stress-induced apoptosis in TBI mice.
Sun G, Zhao Z, Lang J, Sun B, Zhao Q
Neuroscience letters 2022 Jan 23;770:136400
Neuroscience letters 2022 Jan 23;770:136400
Krill Oil Inhibits NLRP3 Inflammasome Activation in the Prevention of the Pathological Injuries of Diabetic Cardiomyopathy.
Sun X, Sun X, Meng H, Wu J, Guo X, Du L, Wu H
Nutrients 2022 Jan 15;14(2)
Nutrients 2022 Jan 15;14(2)
Amelioration of scopolamine-induced learning and memory impairment by the TRPV4 inhibitor HC067047 in ICR mice.
Deng Y, Li W, Niu L, Luo X, Li J, Zhang Y, Liu H, He J, Wan W
Neuroscience letters 2022 Jan 10;767:136209
Neuroscience letters 2022 Jan 10;767:136209
DsbA-L interacts with VDAC1 in mitochondrion-mediated tubular cell apoptosis and contributes to the progression of acute kidney disease.
Li X, Pan J, Li H, Li G, Liu B, Tang X, Liu X, He Z, Peng Z, Zhang H, Wang L, Li Y, Xiang X, Chai X, Yuan Y, Zheng P, Zhang D
EBioMedicine 2022 Feb;76:103859
EBioMedicine 2022 Feb;76:103859
Supervillin Contributes to LPS-induced Inflammatory Response in THP-1 Cell-derived Macrophages.
Zhou J, Que Y, Pan L, Li X, Zhu C, Jin L, Li S
Inflammation 2022 Feb;45(1):356-371
Inflammation 2022 Feb;45(1):356-371
Chronic exposure to biomass ambient particulate matter triggers alveolar macrophage polarization and activation in the rat lung.
Wang S, Chen Y, Hong W, Li B, Zhou Y, Ran P
Journal of cellular and molecular medicine 2022 Feb;26(4):1156-1168
Journal of cellular and molecular medicine 2022 Feb;26(4):1156-1168
Dual effects of bisphenol A on wound healing, involvement of estrogen receptor β.
Wen X, Zhu M, Li Z, Li T, Xu X
Ecotoxicology and environmental safety 2022 Feb;231:113207
Ecotoxicology and environmental safety 2022 Feb;231:113207
KDM2B overexpression prevents myocardial ischemia-reperfusion injury in rats through regulating inflammatory response via the TLR4/NF-κB p65 axis.
Wei Z, Luo L, Hu S, Tian R, Liu Z
Experimental and therapeutic medicine 2022 Feb;23(2):154
Experimental and therapeutic medicine 2022 Feb;23(2):154
MxB inhibits long interspersed element type 1 retrotransposition.
Huang Y, Xu F, Mei S, Liu X, Zhao F, Wei L, Fan Z, Hu Y, Wang L, Ai B, Cen S, Liang C, Guo F
PLoS genetics 2022 Feb;18(2):e1010034
PLoS genetics 2022 Feb;18(2):e1010034
Resveratrol attenuates inflammation and apoptosis through alleviating endoplasmic reticulum stress via Akt/mTOR pathway in fungus-induced allergic airways inflammation.
Wang S, Gong L, Mo Y, Zhang J, Jiang Z, Tian Z, Shao C
International immunopharmacology 2022 Feb;103:108489
International immunopharmacology 2022 Feb;103:108489
Vagus nerve stimulation alleviated cerebral ischemia and reperfusion injury in rats by inhibiting pyroptosis via α7 nicotinic acetylcholine receptor.
Tang H, Li J, Zhou Q, Li S, Xie C, Niu L, Ma J, Li C
Cell death discovery 2022 Feb 8;8(1):54
Cell death discovery 2022 Feb 8;8(1):54
Toddalolactone protects against osteoarthritis by ameliorating chondrocyte inflammation and suppressing osteoclastogenesis.
Xu Y, Xue S, Zhang T, Jin X, Wang C, Lu H, Zhong Y, Chen H, Zhu L, Ma J, Sang W
Chinese medicine 2022 Feb 5;17(1):18
Chinese medicine 2022 Feb 5;17(1):18
RFC2: a prognosis biomarker correlated with the immune signature in diffuse lower-grade gliomas.
Zhao X, Wang Y, Li J, Qu F, Fu X, Liu S, Wang X, Xie Y, Zhang X
Scientific reports 2022 Feb 24;12(1):3122
Scientific reports 2022 Feb 24;12(1):3122
The expression of m6A enzymes in the hippocampus of diabetic cognitive impairment mice and the possible improvement of YTHDF1.
Li M, Zhong X, Zhao Z, Zeng Z, Yuan Q, Xiao X, Zu X, Liu J
Brain research 2022 Feb 15;1777:147766
Brain research 2022 Feb 15;1777:147766
Inhibition of base editors with anti-deaminases derived from viruses.
Liu Z, Chen S, Lai L, Li Z
Nature communications 2022 Feb 1;13(1):597
Nature communications 2022 Feb 1;13(1):597
FAEE exerts a protective effect against osteoporosis by regulating the MAPK signalling pathway.
Wang MY, An MF, Fan MS, Zhang SS, Sun ZR, Zhao YL, Xiang ZM, Sheng J
Pharmaceutical biology 2022 Dec;60(1):467-478
Pharmaceutical biology 2022 Dec;60(1):467-478
Cdk5 Promotes Mitochondrial Fission via Drp1 Phosphorylation at S616 in Chronic Ethanol Exposure-Induced Cognitive Impairment.
Liu D, Li J, Rong X, Li J, Peng Y, Shen Q
Molecular neurobiology 2022 Dec;59(12):7075-7094
Molecular neurobiology 2022 Dec;59(12):7075-7094
Cellular communication network factor 1 interlinks autophagy and ERK signaling to promote osteogenesis of periodontal ligament stem cells.
Li Z, Wu Z, Xi X, Zhao F, Liu H, Liu D
Journal of periodontal research 2022 Dec;57(6):1169-1182
Journal of periodontal research 2022 Dec;57(6):1169-1182
The protective effects of Xuebijing injection on intestinal injuries of mice exposed to irradiation.
Dong Y, Zhang Y, Wang X, Li W, Zhang J, Lu L, Dong H, Fan S, Meng A, Li D
Animal models and experimental medicine 2022 Dec;5(6):565-574
Animal models and experimental medicine 2022 Dec;5(6):565-574
Defective autophagy triggered by arterial cyclic stretch promotes neointimal hyperplasia in vein grafts via the p62/nrf2/slc7a11 signaling pathway.
Chen Y, Bao M, Liu JT, Bao H, Zhang SM, Lou Y, Qi YX
Journal of molecular and cellular cardiology 2022 Dec;173:101-114
Journal of molecular and cellular cardiology 2022 Dec;173:101-114
Attachment of -tBu groups to aza-BODIPY core at 3,5-sites with ultra-large Stokes shift to enhance photothermal therapy through apoptosis mechanism.
Li R, Ren J, Zhang D, Lv M, Wang Z, Wang H, Zhang S, Du J, Jiang XD, Wang G
Materials today. Bio 2022 Dec;16:100446
Materials today. Bio 2022 Dec;16:100446
PVT1/miR-145-5p/HK2 modulates vascular smooth muscle cells phenotype switch via glycolysis: The new perspective on the spiral artery remodeling.
Wu M, Liu W, Huang H, Chen Z, Chen Y, Zhong Y, Jin Z, Liu X, Zou L
Placenta 2022 Dec;130:25-33
Placenta 2022 Dec;130:25-33
mmu-lncRNA 121686/hsa-lncRNA 520657 induced by METTL3 drive the progression of AKI by targeting miR-328-5p/HtrA3 signaling axis.
Pan J, Xie Y, Li H, Li X, Chen J, Liu X, Zhou J, Tang X, He Z, Peng Z, Zhang H, Li Y, Xiang X, Yuan Y, Zhang D
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Dec 7;30(12):3694-3713
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Dec 7;30(12):3694-3713
Proteomic-Based Approach Reveals the Involvement of Apolipoprotein A-I in Related Phenotypes of Autism Spectrum Disorder in the BTBR Mouse Model.
Li Q, Shi Y, Li X, Yang Y, Zhang X, Xu L, Ma Z, Wang J, Fan L, Wu L
International journal of molecular sciences 2022 Dec 4;23(23)
International journal of molecular sciences 2022 Dec 4;23(23)
RNA-m6A modification of HDGF mediated by Mettl3 aggravates the progression of atherosclerosis by regulating macrophages polarization via energy metabolism reprogramming.
Zheng L, Chen X, Yin Q, Gu J, Chen J, Chen M, Zhang Y, Dong M, Jiang H, Yin N, Chen H, Li X
Biochemical and biophysical research communications 2022 Dec 20;635:120-127
Biochemical and biophysical research communications 2022 Dec 20;635:120-127
Effect of miR-143-3p from Extracellular Vesicles of Porcine Uterine Luminal Fluid on Porcine Trophoblast Cells.
Ding Y, Hu Q, Gan J, Zang X, Gu T, Wu Z, Cai G, Hong L
Animals : an open access journal from MDPI 2022 Dec 2;12(23)
Animals : an open access journal from MDPI 2022 Dec 2;12(23)
Melatonin protects oocytes from cadmium exposure-induced meiosis defects by changing epigenetic modification and enhancing mitochondrial morphology in the mouse.
Qu J, Wang Q, Niu H, Sun X, Ji D, Li Y
Ecotoxicology and environmental safety 2022 Dec 15;248:114311
Ecotoxicology and environmental safety 2022 Dec 15;248:114311
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
Zhou X, Zhang X, Zhou X, Abulimiti G, Wang Y, Zhang Q, Cong R, Ji C, Luan J, Yao L, Yang J, Song N
Ecotoxicology and environmental safety 2022 Dec 1;247:114241
Ecotoxicology and environmental safety 2022 Dec 1;247:114241
A synthetic pregnenolone analog promotes microtubule dynamics and neural development.
Kolas V, Bandonil JSA, Wali N, Hsia KC, Shie JJ, Chung BC
Cell & bioscience 2022 Dec 1;12(1):190
Cell & bioscience 2022 Dec 1;12(1):190
Hypoxia facilitates proliferation of smooth muscle cells derived from pluripotent stem cells for vascular tissue engineering.
Fang L, Mei J, Yao B, Liu J, Liu P, Wang X, Zhou J, Lin Z
Journal of tissue engineering and regenerative medicine 2022 Aug;16(8):744-756
Journal of tissue engineering and regenerative medicine 2022 Aug;16(8):744-756
ROS-responsive polymer nanoparticles with enhanced loading of dexamethasone effectively modulate the lung injury microenvironment.
Muhammad W, Zhu J, Zhai Z, Xie J, Zhou J, Feng X, Feng B, Pan Q, Li S, Venkatesan R, Li P, Cao H, Gao C
Acta biomaterialia 2022 Aug;148:258-270
Acta biomaterialia 2022 Aug;148:258-270
Cypermethrin inhibits proliferation of Sertoli cells through AR involving DAB2IP/PI3K/AKT signaling pathway in vitro.
Wang Q, Wang XX, Xie JF, Yao TT, Xu LL, Wang LS, Yu Y, Xu LC
Toxicology research 2022 Aug;11(4):583-591
Toxicology research 2022 Aug;11(4):583-591
Effect of Silkworm Pupa Protein Hydrolysates on Proliferation of Gastric Cancer Cells In Vitro.
Li W, Mu L, Zou Y, Wang W, Zhao H, Wu X, Liao S
Foods (Basel, Switzerland) 2022 Aug 7;11(15)
Foods (Basel, Switzerland) 2022 Aug 7;11(15)
The Exocyst Is Required for CD36 Fatty Acid Translocase Trafficking and Free Fatty Acid Uptake in Skeletal Muscle Cells.
Nakamura NK, Tokunaga DS, Ha HY, Polgar N
Cells 2022 Aug 6;11(15)
Cells 2022 Aug 6;11(15)
Chemical profile and miscarriage prevention evaluation of Jiao-Ai Decoction, a classical traditional Chinese formula.
Zhang M, Geng T, Jing SH, Li L, Wang K, Zhang Q, Zhang Y, Zhou SK, Gao P, Ding AW, Zhang L
Journal of pharmaceutical and biomedical analysis 2022 Aug 5;217:114832
Journal of pharmaceutical and biomedical analysis 2022 Aug 5;217:114832
Inhibition of BET Family Proteins Suppresses African Swine Fever Virus Infection.
Zhao Y, Niu Q, Yang S, Yang J, Zhang Z, Geng S, Fan J, Liu Z, Guan G, Liu Z, Zhou J, Hu H, Luo J, Yin H
Microbiology spectrum 2022 Aug 31;10(4):e0241921
Microbiology spectrum 2022 Aug 31;10(4):e0241921
The mechanism on Prevotella melaninogenica promoting the inflammatory progression of oral lichen planus.
Xu P, Shao RR, Zhang S, Tan ZW, Guo YT, He Y
Clinical and experimental immunology 2022 Aug 19;209(2):215-224
Clinical and experimental immunology 2022 Aug 19;209(2):215-224
Aperture Modulation of Isoreticular Metal Organic Frameworks for Targeted Antitumor Drug Delivery.
Cai M, Liang W, Wang K, Yin D, Fu T, Zhu R, Qu C, Dong X, Ni J, Yin X
ACS applied materials & interfaces 2022 Aug 17;14(32):36366-36378
ACS applied materials & interfaces 2022 Aug 17;14(32):36366-36378
Quantitative proteomics and functional analysis identified novel targets for missed abortion.
Chen X, Zheng Q, Ji L, Zhuang Y, Yu H, Cheng X, Han Y, Lv J, Zheng B, Zheng Y, Yu J
Experimental cell research 2022 Aug 15;417(2):113216
Experimental cell research 2022 Aug 15;417(2):113216
Apextrin from Ruditapes philippinarum functions as pattern recognition receptor and modulates NF-κB pathway.
Jiang K, Nie H, Yin Z, Yan X, Li Q
International journal of biological macromolecules 2022 Aug 1;214:33-44
International journal of biological macromolecules 2022 Aug 1;214:33-44
Cognitive enhancement and neuroprotective effects of OABL, a sesquiterpene lactone in 5xFAD Alzheimer's disease mice model.
Tang JJ, Huang LF, Deng JL, Wang YM, Guo C, Peng XN, Liu Z, Gao JM
Redox biology 2022 Apr;50:102229
Redox biology 2022 Apr;50:102229
O-GlcNAc transferase promotes the nuclear localization of the focal adhesion-associated protein Zyxin to regulate UV-induced cell death.
Zhao Y, Yue S, Zhou X, Guo J, Ma S, Chen Q
The Journal of biological chemistry 2022 Apr;298(4):101776
The Journal of biological chemistry 2022 Apr;298(4):101776
Protective Effects of Scutellarin on Acute Alcohol Intestinal Injury.
Liu F, Gao X, Li Z, Zhang X, Fan H, Yu G, Bello BK, Feng X, Li D, Teng D, Chen Y, Zhao P, Fu M, Dong J
Chemistry & biodiversity 2022 Apr;19(4):e202100856
Chemistry & biodiversity 2022 Apr;19(4):e202100856
The lncRNA MIAT regulates CPT-1a mediated cardiac hypertrophy through m(6)A RNA methylation reading protein Ythdf2.
Yang Y, Mbikyo MB, Zhang J, Zhang Y, Zhang N, Li Z
Cell death discovery 2022 Apr 5;8(1):167
Cell death discovery 2022 Apr 5;8(1):167
IL-37 isoform D acts as an inhibitor of soluble ST2 to boost type 2 immune homeostasis in white adipose tissue.
Li C, Zhao M, Zhao M, Chen N, Guo Y, Du Y, Zhang Y, Cao B, Zhan B, Guo C, Li Y, Li Y, Shi Y, Zhu F, Zhang L, Wang Q
Cell death discovery 2022 Apr 5;8(1):163
Cell death discovery 2022 Apr 5;8(1):163
Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue.
Rosina M, Ceci V, Turchi R, Chuan L, Borcherding N, Sciarretta F, Sánchez-Díaz M, Tortolici F, Karlinsey K, Chiurchiù V, Fuoco C, Giwa R, Field RL, Audano M, Arena S, Palma A, Riccio F, Shamsi F, Renzone G, Verri M, Crescenzi A, Rizza S, Faienza F, Filomeni G, Kooijman S, Rufini S, de Vries AAF, Scaloni A, Mitro N, Tseng YH, Hidalgo A, Zhou B, Brestoff JR, Aquilano K, Lettieri-Barbato D
Cell metabolism 2022 Apr 5;34(4):533-548.e12
Cell metabolism 2022 Apr 5;34(4):533-548.e12
The Tobacco β-Cembrenediol: A Prostate Cancer Recurrence Suppressor Lead and Prospective Scaffold via Modulation of Indoleamine 2,3-Dioxygenase and Tryptophan Dioxygenase.
Mudhish EA, Siddique AB, Ebrahim HY, Abdelwahed KS, King JA, El Sayed KA
Nutrients 2022 Apr 4;14(7)
Nutrients 2022 Apr 4;14(7)
The plant hormone abscisic acid stimulates megakaryocyte differentiation from human iPSCs in vitro.
Huang W, Gu H, Zhan Z, Wang R, Song L, Zhang Y, Zhang Y, Li S, Li J, Zang Y, Li Y, Qian B
Platelets 2022 Apr 3;33(3):462-470
Platelets 2022 Apr 3;33(3):462-470
Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.
Li Y, Zhu Y, Chu B, Liu N, Chen S, Wang J, Zou Y
International journal of molecular sciences 2022 Apr 28;23(9)
International journal of molecular sciences 2022 Apr 28;23(9)
ORP5 promotes tumor metastasis via stabilizing c-Met in renal cell carcinoma.
Song L, Zhang L, Zhou Y, Shao X, Xu Y, Pei D, Wang Q
Cell death discovery 2022 Apr 21;8(1):219
Cell death discovery 2022 Apr 21;8(1):219
Age-related visual impairments and retinal ganglion cells axonal degeneration in a mouse model harboring OPTN (E50K) mutation.
Hou M, Shao Z, Zhang S, Liu X, Fan P, Jiang M, Zhao Y, Xiao R, Yuan H
Cell death & disease 2022 Apr 18;13(4):362
Cell death & disease 2022 Apr 18;13(4):362
Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma.
Chen G, Kong P, Yang M, Hu W, Prise KM, Yu KN, Cui S, Qin F, Meng G, Almahi WA, Nie L, Han W
International journal of radiation oncology, biology, physics 2022 Apr 1;112(5):1216-1228
International journal of radiation oncology, biology, physics 2022 Apr 1;112(5):1216-1228
Bioinformatic Approach to Unveil Key Differentially Expressed Proteins in Human Sperm After Slow and Rapid Cryopreservation.
Corda PO, Silva JV, Pereira SC, Barros A, Alves MG, Fardilha M
Frontiers in cell and developmental biology 2021;9:759354
Frontiers in cell and developmental biology 2021;9:759354
The Regulatory Role of GBF1 on Osteoclast Activation Through EIF2a Mediated ER Stress and Novel Marker FAM129A Induction.
Wen C, Zhou Y, Xu Y, Tan H, Pang C, Liu H, Liu K, Wei L, Luo H, Qin T, He C, Liu C, Zhou C
Frontiers in cell and developmental biology 2021;9:706768
Frontiers in cell and developmental biology 2021;9:706768
Tributyltin Oxide Exposure During in vitro Maturation Disrupts Oocyte Maturation and Subsequent Embryonic Developmental Competence in Pigs.
Xiao Y, Yuan B, Hu W, Qi J, Jiang H, Sun B, Zhang J, Liang S
Frontiers in cell and developmental biology 2021;9:683448
Frontiers in cell and developmental biology 2021;9:683448
Iron Overload-Induced Ferroptosis Impairs Porcine Oocyte Maturation and Subsequent Embryonic Developmental Competence in vitro.
Hu W, Zhang Y, Wang D, Yang T, Qi J, Zhang Y, Jiang H, Zhang J, Sun B, Liang S
Frontiers in cell and developmental biology 2021;9:673291
Frontiers in cell and developmental biology 2021;9:673291
The m(6)A Reader YTHDF1 Facilitates the Tumorigenesis and Metastasis of Gastric Cancer via USP14 Translation in an m(6)A-Dependent Manner.
Chen XY, Liang R, Yi YC, Fan HN, Chen M, Zhang J, Zhu JS
Frontiers in cell and developmental biology 2021;9:647702
Frontiers in cell and developmental biology 2021;9:647702
Mechanically Activated Calcium Channel PIEZO1 Modulates Radiation-Induced Epithelial-Mesenchymal Transition by Forming a Positive Feedback With TGF-β1.
Huang JQ, Zhang H, Guo XW, Lu Y, Wang SN, Cheng B, Dong SH, Lyu XL, Li FS, Li YW
Frontiers in molecular biosciences 2021;8:725275
Frontiers in molecular biosciences 2021;8:725275
Expression and Functional Analysis of lncRNAs Involved in Platelet-Derived Growth Factor-BB-Induced Proliferation of Human Aortic Smooth Muscle Cells.
Lin JJ, Chen W, Gong M, Xu X, Du MY, Wang SF, Yang LY, Wang Y, Liu KX, Kong P, Li B, Liu K, Li YM, Dong LH, Sun SG
Frontiers in cardiovascular medicine 2021;8:702718
Frontiers in cardiovascular medicine 2021;8:702718
Transcriptome Differences in Pig Tracheal Epithelial Cells in Response to Pasteurella Multocida Infection.
Wang X, Wang F, Lin L, Liang W, Liu S, Hua L, Wang X, Chen H, Peng Z, Wu B
Frontiers in veterinary science 2021;8:682514
Frontiers in veterinary science 2021;8:682514
DCI after Aneurysmal Subarachnoid Hemorrhage Is Related to the Expression of MFG-E8.
Chen X, Jiang Y, Liu J, Wang C, Wan D, Liang A, Leng J, Yang Y, Xiang H, Liu R
BioMed research international 2021;2021:6568477
BioMed research international 2021;2021:6568477
USP37 downregulation elevates the Chemical Sensitivity of Human Breast Cancer Cells to Adriamycin.
Qin T, Cui XY, Xiu H, Huang C, Sun ZN, Xu XM, Li LH, Yue L
International journal of medical sciences 2021;18(2):325-334
International journal of medical sciences 2021;18(2):325-334
MnSOD Lysine 68 acetylation leads to cisplatin and doxorubicin resistance due to aberrant mitochondrial metabolism.
Gao Y, Zhu Y, Tran EL, Tokars V, Dean AE, Quan S, Gius D
International journal of biological sciences 2021;17(5):1203-1216
International journal of biological sciences 2021;17(5):1203-1216
Rosuvastatin Nanomicelles Target Neuroinflammation and Improve Neurological Deficit in a Mouse Model of Intracerebral Hemorrhage.
Zi L, Zhou W, Xu J, Li J, Li N, Xu J, You C, Wang C, Tian M
International journal of nanomedicine 2021;16:2933-2947
International journal of nanomedicine 2021;16:2933-2947
GluN2A/ERK/CREB Signaling Pathway Involved in Electroacupuncture Regulating Hypothalamic-Pituitary-Adrenal Axis Hyperactivity.
Wang Y, Han J, Zhu J, Zhang M, Ju M, Du Y, Tian Z
Frontiers in neuroscience 2021;15:703044
Frontiers in neuroscience 2021;15:703044
Latent Sex Differences in CaMKII-nNOS Signaling That Underlie Antidepressant-Like Effects of Yueju-Ganmaidazao Decoction in the Hippocampus.
Yin Y, Qian S, Chen Y, Sun Y, Li Y, Yu Y, Li J, Wu Z, Yu X, Ge R, Han J, Sun D, Wu H, Liu L, Xue W, Wang W
Frontiers in behavioral neuroscience 2021;15:640258
Frontiers in behavioral neuroscience 2021;15:640258
PADI6 Regulates Trophoblast Cell Migration-Invasion Through the Hippo/YAP1 Pathway in Hydatidiform Moles.
Huang B, Zhao Y, Zhou L, Gong T, Feng J, Han P, Qian J
Journal of inflammation research 2021;14:3489-3500
Journal of inflammation research 2021;14:3489-3500
RNF128 suppresses the malignancy of colorectal cancer cells via inhibition of Wnt/β-catenin signaling.
Zhu Y, Gan Y, Zou R, Sha H, Lu Y, Zhang Y, Feng J
American journal of translational research 2021;13(12):13567-13578
American journal of translational research 2021;13(12):13567-13578
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Cai C, Hu W, Zhang Y, Hu X, Yang S, Qiu H, Wang R, Ma M, Qiu Y, Chu T
Frontiers in pharmacology 2021;12:772540
Frontiers in pharmacology 2021;12:772540
Ilexsaponin A(1) Ameliorates Diet-Induced Nonalcoholic Fatty Liver Disease by Regulating Bile Acid Metabolism in Mice.
Zhao WW, Xiao M, Wu X, Li XW, Li XX, Zhao T, Yu L, Chen XQ
Frontiers in pharmacology 2021;12:771976
Frontiers in pharmacology 2021;12:771976
Loss of Diacylglycerol Kinase α Enhances Macrophage Responsiveness.
Manigat LC, Granade ME, Taori S, Miller CA, Vass LR, Zhong XP, Harris TE, Purow BW
Frontiers in immunology 2021;12:722469
Frontiers in immunology 2021;12:722469
ZnT8 Deficiency Protects From APAP-Induced Acute Liver Injury by Reducing Oxidative Stress Through Upregulating Hepatic Zinc and Metallothioneins.
Su W, Feng M, Liu Y, Cao R, Liu Y, Tang J, Pan K, Lan R, Mao Z
Frontiers in pharmacology 2021;12:721471
Frontiers in pharmacology 2021;12:721471
The Downregulation of eIF3a Contributes to Vemurafenib Resistance in Melanoma by Activating ERK via PPP2R1B.
Jiang SL, Wang ZB, Zhu T, Jiang T, Fei JF, Liu C, Luo C, Cheng Y, Liu ZQ
Frontiers in pharmacology 2021;12:720619
Frontiers in pharmacology 2021;12:720619
CXCL5 Downregulation in Villous Tissue Is Correlated With Recurrent Spontaneous Abortion.
Zhang S, Ding J, Wang J, Yin T, Zhang Y, Yang J
Frontiers in immunology 2021;12:717483
Frontiers in immunology 2021;12:717483
Protective Effect of Remdesivir Against Pulmonary Fibrosis in Mice.
Li X, Liu R, Cui Y, Liang J, Bi Z, Li S, Miao Y, Zhang L, Li X, Zhou H, Yang C
Frontiers in pharmacology 2021;12:692346
Frontiers in pharmacology 2021;12:692346
Chlorogenic Acid Ameliorates Damage Induced by Fluorene-9-Bisphenol in Porcine Sertoli Cells.
Zhang S, Sun B, Wang D, Liu Y, Li J, Qi J, Zhang Y, Bai C, Liang S
Frontiers in pharmacology 2021;12:678772
Frontiers in pharmacology 2021;12:678772
Human umbilical cord-derived mesenchymal stem cell therapy ameliorates lupus through increasing CD4+ T cell senescence via MiR-199a-5p/Sirt1/p53 axis.
Cheng T, Ding S, Liu S, Li Y, Sun L
Theranostics 2021;11(2):893-905
Theranostics 2021;11(2):893-905
circCDYL2, Overexpressed in Highly Migratory Colorectal Cancer Cells, Promotes Migration by Binding to Ezrin.
Li X, Wang J, Long H, Lin W, Wang H, Chen Y, Yuan Q, Li X
Frontiers in oncology 2021;11:716073
Frontiers in oncology 2021;11:716073
The Role of KDM2B and EZH2 in Regulating the Stemness in Colorectal Cancer Through the PI3K/AKT Pathway.
Sanches JGP, Song B, Zhang Q, Cui X, Yabasin IB, Ntim M, Li X, He J, Zhang Y, Mao J, Lu Y, Li L
Frontiers in oncology 2021;11:637298
Frontiers in oncology 2021;11:637298
Expression and prognostic potential of PLEK2 in head and neck squamous cell carcinoma based on bioinformatics analysis.
Wang J, Sun Z, Wang J, Tian Q, Huang R, Wang H, Wang X, Han F
Cancer medicine 2021 Sep;10(18):6515-6533
Cancer medicine 2021 Sep;10(18):6515-6533
Therapy of spinal cord injury by zinc modified gold nanoclusters via immune-suppressing strategies.
Lin S, Li D, Zhou Z, Xu C, Mei X, Tian H
Journal of nanobiotechnology 2021 Sep 20;19(1):281
Journal of nanobiotechnology 2021 Sep 20;19(1):281
TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity.
Bi J, Cheng C, Zheng C, Huang C, Zheng X, Wan X, Chen YH, Tian Z, Sun H
Science advances 2021 Sep 17;7(38):eabi6515
Science advances 2021 Sep 17;7(38):eabi6515
Protocol for nuclear export signal characterization of cGAS in mammalian cells.
Huang Y, McLean M, Liang C, Guo F
STAR protocols 2021 Sep 17;2(3):100649
STAR protocols 2021 Sep 17;2(3):100649
Yixin-Fumai granules improve sick sinus syndrome in aging mice through Nrf-2/HO-1 pathway: A new target for sick sinus syndrome.
Zhang H, Li L, Hao M, Chen K, Lu Y, Qi J, Chen W, Ren L, Cai X, Chen C, Liu Z, Zhao B, Li Z, Hou P
Journal of ethnopharmacology 2021 Sep 15;277:114254
Journal of ethnopharmacology 2021 Sep 15;277:114254
MicroRNA‑8063 targets heterogeneous nuclear ribonucleoprotein AB to inhibit the self‑renewal of colorectal cancer stem cells via the Wnt/β‑catenin pathway.
Chen ZQ, Yuan T, Jiang H, Yang YY, Wang L, Fu RM, Luo SQ, Zhang T, Wu ZY, Wen KM
Oncology reports 2021 Oct;46(4)
Oncology reports 2021 Oct;46(4)
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Li XJ, Zhang YY, Fu YH, Zhang H, Li HX, Li QF, Li HL, Tan RK, Jiang CX, Jiang W, Li ZX, Luo C, Lu BX, Dang YJ
Acta pharmacologica Sinica 2021 Oct;42(10):1556-1566
Acta pharmacologica Sinica 2021 Oct;42(10):1556-1566
Cucurbit[7]uril as a Broad-Spectrum Antiviral Agent against Diverse RNA Viruses.
Quan J, Zhang X, Ding Y, Li S, Qiu Y, Wang R, Zhou X
Virologica Sinica 2021 Oct;36(5):1165-1176
Virologica Sinica 2021 Oct;36(5):1165-1176
ZBP1-MLKL necroptotic signaling potentiates radiation-induced antitumor immunity via intratumoral STING pathway activation.
Yang Y, Wu M, Cao D, Yang C, Jin J, Wu L, Hong X, Li W, Lu L, Li J, Wang X, Meng X, Zhang Z, Cheng J, Ye Y, Xiao H, Yu J, Deng L
Science advances 2021 Oct 8;7(41):eabf6290
Science advances 2021 Oct 8;7(41):eabf6290
NORHA, a novel follicular atresia-related lncRNA, promotes porcine granulosa cell apoptosis via the miR-183-96-182 cluster and FoxO1 axis.
Yao W, Pan Z, Du X, Zhang J, Liu H, Li Q
Journal of animal science and biotechnology 2021 Oct 7;12(1):103
Journal of animal science and biotechnology 2021 Oct 7;12(1):103
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Wang D, He J, Dong J, Wu S, Liu S, Zhu H, Xu T
Cancer letters 2021 Oct 28;519:2-19
Cancer letters 2021 Oct 28;519:2-19
Frugoside delays osteoarthritis progression via inhibiting miR-155-modulated synovial macrophage M1 polarization.
Wang H, Zhang H, Fan K, Zhang D, Hu A, Zeng X, Liu YL, Tan G, Wang H
Rheumatology (Oxford, England) 2021 Oct 2;60(10):4899-4909
Rheumatology (Oxford, England) 2021 Oct 2;60(10):4899-4909
Naringin Promotes Skeletal Muscle Fiber Remodeling by the AdipoR1-APPL1-AMPK Signaling Pathway.
Li P, Zhang S, Song H, Traore SS, Li J, Raubenheimer D, Cui Z, Kou G
Journal of agricultural and food chemistry 2021 Oct 13;69(40):11890-11899
Journal of agricultural and food chemistry 2021 Oct 13;69(40):11890-11899
Comparative Proteomics of Rat Olfactory Bulb Reveal Insights into Susceptibility and Resiliency to Chronic-stress-induced Depression or Anxiety.
Liu D, Cai X, Wang L, Yi F, Liao W, Huang R, Fang C, Chen J, Zhou J
Neuroscience 2021 Oct 1;473:29-43
Neuroscience 2021 Oct 1;473:29-43
Arsenic trioxide induces expression of BCL-2 expression via NF-κB and p38 MAPK signaling pathways in BEAS-2B cells during apoptosis.
Tang J, Yao C, Liu Y, Yuan J, Wu L, Hosoi K, Yu S, Huang C, Wei H, Chen G
Ecotoxicology and environmental safety 2021 Oct 1;222:112531
Ecotoxicology and environmental safety 2021 Oct 1;222:112531
Reduced activity of intestinal surface Na(+)/H(+) exchanger NHE3 is a key factor for induction of diarrhea after PEDV infection in neonatal piglets.
Song Z, Yan T, Ran L, Niu Z, Zhang Y, Kan Z, Xu S, Zhang S, Zhang J, Zou H, Lei C
Virology 2021 Nov;563:64-73
Virology 2021 Nov;563:64-73
Tripartite motif-containing protein 16 protects against myocardial ischemia/reperfusion injury by affecting the Keap1/Nrf2 axis.
Cui Q, Yan L
Cell and tissue research 2021 Nov;386(2):349-363
Cell and tissue research 2021 Nov;386(2):349-363
EGFR and ERK activation resists flavonoid quercetin-induced anticancer activities in human cervical cancer cells in vitro.
Chen X, Xu P, Zhang H, Su X, Guo L, Zhou X, Wang J, Huang P, Zhang Q, Sun R
Oncology letters 2021 Nov;22(5):754
Oncology letters 2021 Nov;22(5):754
Guaiazulene derivative 1,2,3,4-tetrahydroazuleno[1,2-b] tropone reduces the production of ATP by inhibiting electron transfer complex II.
Kasami C, Yamaguchi JI, Inoue H
FEBS open bio 2021 Nov;11(11):2921-2932
FEBS open bio 2021 Nov;11(11):2921-2932
Vagus nerve stimulation mediates microglia M1/2 polarization via inhibition of TLR4 pathway after ischemic stroke.
Zhang L, Liu Y, Wang S, Long L, Zang Q, Ma J, Yu L, Jia G
Biochemical and biophysical research communications 2021 Nov 5;577:71-79
Biochemical and biophysical research communications 2021 Nov 5;577:71-79
A network pharmacology approach to reveal the pharmacological targets and biological mechanism of compound kushen injection for treating pancreatic cancer based on WGCNA and in vitro experiment validation.
Wu C, Huang ZH, Meng ZQ, Fan XT, Lu S, Tan YY, You LM, Huang JQ, Stalin A, Ye PZ, Wu ZS, Zhang JY, Liu XK, Zhou W, Zhang XM, Wu JR
Chinese medicine 2021 Nov 22;16(1):121
Chinese medicine 2021 Nov 22;16(1):121
Inhibition of the NLRP3 inflammasome with MCC950 prevents chronic social isolation-induced depression-like behavior in male mice.
Li W, Niu L, Liu Z, Xu X, Shi M, Zhang Y, Deng Y, He J, Xu Y, Wan W, Sun Q, Zhong X, Cao W
Neuroscience letters 2021 Nov 20;765:136290
Neuroscience letters 2021 Nov 20;765:136290
1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-κB/MAPK pathways.
Tang JJ, Wang MR, Dong S, Huang LF, He QR, Gao JM
European journal of medicinal chemistry 2021 Nov 15;224:113713
European journal of medicinal chemistry 2021 Nov 15;224:113713
Iptakalim alleviates synaptic damages via targeting mitochondrial ATP-sensitive potassium channel in depression.
Guo W, Tang ZY, Cai ZY, Zhao WE, Yang J, Wang XP, Ji J, Huang XX, Sun XL
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21581
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21581
Characterization of ALTO-encoding circular RNAs expressed by Merkel cell polyomavirus and trichodysplasia spinulosa polyomavirus.
Yang R, Lee EE, Kim J, Choi JH, Kolitz E, Chen Y, Crewe C, Salisbury NJH, Scherer PE, Cockerell C, Smith TR, Rosen L, Verlinden L, Galloway DA, Buck CB, Feltkamp MC, Sullivan CS, Wang RC
PLoS pathogens 2021 May;17(5):e1009582
PLoS pathogens 2021 May;17(5):e1009582
Extracellular vesicles-based pre-targeting strategy enables multi-modal imaging of orthotopic colon cancer and image-guided surgery.
Jing B, Qian R, Jiang D, Gai Y, Liu Z, Guo F, Ren S, Gao Y, Lan X, An R
Journal of nanobiotechnology 2021 May 22;19(1):151
Journal of nanobiotechnology 2021 May 22;19(1):151
Functional domains and amino acid residues of Japanese eel IRF1, AjIRF1, regulate its nuclear import and IFN/Mx promoter activation.
Li W, Ling L, Wang Z, Liang Y, Huang W, Nie P, Huang B
Developmental and comparative immunology 2021 Mar;116:103923
Developmental and comparative immunology 2021 Mar;116:103923
Inhibition of ERAD synergizes with FTS to eradicate pancreatic cancer cells.
Du R, Sullivan DK, Azizian NG, Liu Y, Li Y
BMC cancer 2021 Mar 6;21(1):237
BMC cancer 2021 Mar 6;21(1):237
The combination of G-CSF and AMD3100 mobilizes bone marrow-derived stem cells to protect against cisplatin-induced acute kidney injury in mice.
Chen Z, Ren X, Ren R, Wang Y, Shang J
Stem cell research & therapy 2021 Mar 24;12(1):209
Stem cell research & therapy 2021 Mar 24;12(1):209
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Han D, Xu Y, Peng WP, Feng F, Wang Z, Gu C, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
lncRNA Ttc3-209 Promotes the Apoptosis of Retinal Ganglion Cells in Retinal Ischemia Reperfusion Injury by Targeting the miR-484/Wnt8a Axis.
Zhang R, Feng Y, Lu J, Ge Y, Li H
Investigative ophthalmology & visual science 2021 Mar 1;62(3):13
Investigative ophthalmology & visual science 2021 Mar 1;62(3):13
Sesamin induces cell cycle arrest and apoptosis through p38/C-Jun N-terminal kinase mitogen-activated protein kinase pathways in human colorectal cancer cells.
Wang X, Qiao J, Zou C, Zhao Y, Huang Y
Anti-cancer drugs 2021 Mar 1;32(3):248-256
Anti-cancer drugs 2021 Mar 1;32(3):248-256
Pharmacological effects of indole alkaloids from Alstonia scholaris (L.) R. Br. on pulmonary fibrosis in vivo.
Zhao YL, Pu SB, Qi Y, Wu BF, Shang JH, Liu YP, Hu D, Luo XD
Journal of ethnopharmacology 2021 Mar 1;267:113506
Journal of ethnopharmacology 2021 Mar 1;267:113506
Glycine alleviates fluoride-induced oxidative stress, apoptosis and senescence in a porcine testicular Sertoli cell line.
Liu Y, Sun B, Zhang S, Li J, Qi J, Bai C, Zhang J, Liang S
Reproduction in domestic animals = Zuchthygiene 2021 Jun;56(6):884-896
Reproduction in domestic animals = Zuchthygiene 2021 Jun;56(6):884-896
Alternative splicing transitions associate with emerging atrophy phenotype during denervation-induced skeletal muscle atrophy.
Qiu J, Wu L, Chang Y, Sun H, Sun J
Journal of cellular physiology 2021 Jun;236(6):4496-4514
Journal of cellular physiology 2021 Jun;236(6):4496-4514
Melatonin ameliorates cypermethrin-induced impairments by regulating oxidative stress, DNA damage and apoptosis in porcine Sertoli cells.
Li J, Sun BX, Wang DL, Liu Y, Qi JJ, Nie XW, Bai CY, Zhang JB, Liang S
Theriogenology 2021 Jun;167:67-76
Theriogenology 2021 Jun;167:67-76
Resolving the graft ischemia-reperfusion injury during liver transplantation at the single cell resolution.
Wang L, Li J, He S, Liu Y, Chen H, He S, Yin M, Zou D, Chen S, Luo T, Yu X, Wan X, Huang S, Guo Z, He X
Cell death & disease 2021 Jun 8;12(6):589
Cell death & disease 2021 Jun 8;12(6):589
Ameliorative effects of eosinophil deficiency on immune response, endoplasmic reticulum stress, apoptosis, and autophagy in fungus-induced allergic lung inflammation.
Wang S, Jiang Z, Li L, Zhang J, Zhang C, Shao C
Respiratory research 2021 Jun 7;22(1):173
Respiratory research 2021 Jun 7;22(1):173
Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
Chen Z, Chen Y, Li Y, Lian W, Zheng K, Zhang Y, Zhang Y, Lin C, Liu C, Sun F, Sun X, Wang J, Zhao L, Ke Y
Cell death & disease 2021 Jun 15;12(6):615
Cell death & disease 2021 Jun 15;12(6):615
PI3K/AKT pathway mediates the antidepressant- and anxiolytic-like roles of hydrogen sulfide in streptozotocin-induced diabetic rats via promoting hippocampal neurogenesis.
Jiang W, Tang YY, Zhu WW, Li C, Zhang P, Li RQ, Chen YJ, Zou W, Tang XQ
Neurotoxicology 2021 Jul;85:201-208
Neurotoxicology 2021 Jul;85:201-208
AEG-1 Knockdown Sensitizes Glioma Cells to Radiation Through Impairing Homologous Recombination Via Targeting RFC5.
Zhao X, Sun Y, Sun X, Li J, Shi X, Liang Z, Ma Y, Zhang X
DNA and cell biology 2021 Jul;40(7):895-905
DNA and cell biology 2021 Jul;40(7):895-905
The role of SAMM50 in non-alcoholic fatty liver disease: from genetics to mechanisms.
Li Z, Shen W, Wu G, Qin C, Zhang Y, Wang Y, Song G, Xiao C, Zhang X, Deng G, Wang R, Wang X
FEBS open bio 2021 Jul;11(7):1893-1906
FEBS open bio 2021 Jul;11(7):1893-1906
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking.
Wang F, Chen X, Cheng H, Song L, Liu J, Caplan S, Zhu L, Wu JY
EMBO reports 2021 Jul 5;22(7):e52006
EMBO reports 2021 Jul 5;22(7):e52006
Theaflavin Promotes Mitochondrial Abundance and Glucose Absorption in Myotubes by Activating the CaMKK2-AMPK Signal Axis via Calcium-Ion Influx.
Qu Z, Liu A, Liu C, Tang Q, Zhan L, Xiao W, Huang J, Liu Z, Zhang S
Journal of agricultural and food chemistry 2021 Jul 28;69(29):8144-8159
Journal of agricultural and food chemistry 2021 Jul 28;69(29):8144-8159
Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model.
Duan A, Shen K, Li B, Li C, Zhou H, Kong R, Shao Y, Qin J, Yuan T, Ji J, Guo W, Wang X, Xue T, Li L, Huang X, Sun Y, Cai Z, Liu W, Liu F
Stem cell research & therapy 2021 Jul 28;12(1):427
Stem cell research & therapy 2021 Jul 28;12(1):427
Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB.
Ge W, Wang Y, Zheng S, Zhao D, Wang X, Zhang X, Hu Y
Cell death discovery 2021 Jul 26;7(1):195
Cell death discovery 2021 Jul 26;7(1):195
Attractin Gene Deficiency in Rats Leads to Impairments in Both Activity and Spatial Learning and Memory.
Li XH, Xue C, Liu MQ, Zhang MY, Zhou Y, Xiao X, Wang J, Xu XJ, Shi Y, Zhang WN
Neuroscience 2021 Jul 1;466:101-108
Neuroscience 2021 Jul 1;466:101-108
Betulinic acid attenuated bleomycin-induced pulmonary fibrosis by effectively intervening Wnt/β-catenin signaling.
Li X, Liu X, Deng R, Gao S, Jiang Q, Liu R, Li H, Miao Y, Zhai Y, Zhang S, Wang Z, Ren Y, Ning W, Zhou H, Yang C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153428
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153428
ETV5 Regulates Hepatic Fatty Acid Metabolism Through PPAR Signaling Pathway.
Mao Z, Feng M, Li Z, Zhou M, Xu L, Pan K, Wang S, Su W, Zhang W
Diabetes 2021 Jan;70(1):214-226
Diabetes 2021 Jan;70(1):214-226
Identification and Bioinformatic Assessment of circRNA Expression After RMI1 Knockdown and Ionizing Radiation Exposure.
Sun Y, Fang L, Yang M, He N, Wang J, Zhang M, Ji K, Wang Q, Liu Y, Du L, Wang Y, Xu C, Liu Q
DNA and cell biology 2021 Jan;40(1):80-92
DNA and cell biology 2021 Jan;40(1):80-92
NADPH levels affect cellular epigenetic state by inhibiting HDAC3-Ncor complex.
Li W, Kou J, Qin J, Li L, Zhang Z, Pan Y, Xue Y, Du W
Nature metabolism 2021 Jan;3(1):75-89
Nature metabolism 2021 Jan;3(1):75-89
Libertellenone H, a Natural Pimarane Diterpenoid, Inhibits Thioredoxin System and Induces ROS-Mediated Apoptosis in Human Pancreatic Cancer Cells.
Zhang W, Zhu Y, Yu H, Liu X, Jiao B, Lu X
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
Yang J, Cao LL, Wang XP, Guo W, Guo RB, Sun YQ, Xue TF, Cai ZY, Ji J, Cheng H, Sun XL
Cell death & disease 2021 Jan 6;12(1):23
Cell death & disease 2021 Jan 6;12(1):23
TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.
Zhang HT, Zeng Q, Wu B, Lu J, Tong KL, Lin J, Liu QY, Xu L, Yang J, Liu X, Liu W, Zhang YF, Lian Q, Liu L, Gao X
Cell death & disease 2021 Jan 6;12(1):21
Cell death & disease 2021 Jan 6;12(1):21
A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA.
Sun H, Huang Y, Mei S, Xu F, Liu X, Zhao F, Yin L, Zhang D, Wei L, Wu C, Ma S, Wang J, Cen S, Liang C, Hu S, Guo F
Cell reports 2021 Jan 5;34(1):108586
Cell reports 2021 Jan 5;34(1):108586
Formaldehyde induces ferroptosis in hippocampal neuronal cells by upregulation of the Warburg effect.
Li XN, Yang SQ, Li M, Li XS, Tian Q, Xiao F, Tang YY, Kang X, Wang CY, Zou W, Zhang P, Tang XQ
Toxicology 2021 Jan 30;448:152650
Toxicology 2021 Jan 30;448:152650
CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson's disease.
Hu Z, Mao C, Wang H, Zhang Z, Zhang S, Luo H, Tang M, Yang J, Yuan Y, Wang Y, Liu Y, Fan L, Zhang Q, Yao D, Liu F, Schisler JC, Shi C, Xu Y
Aging 2021 Jan 2;13(1):1458-1472
Aging 2021 Jan 2;13(1):1458-1472
PDGF/MEK/ERK axis represses Ca(2+) clearance via decreasing the abundance of plasma membrane Ca(2+) pump PMCA4 in pulmonary arterial smooth muscle cells.
Deng L, Chen J, Wang T, Chen B, Yang L, Liao J, Chen Y, Wang J, Tang H, Yi J, Kang K, Li L, Gou D
American journal of physiology. Cell physiology 2021 Jan 1;320(1):C66-C79
American journal of physiology. Cell physiology 2021 Jan 1;320(1):C66-C79
BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.
Xue W, Yao X, Ting G, Ling J, Huimin L, Yuan Q, Chun Z, Ming Z, Yuanzhen Z
Environmental pollution (Barking, Essex : 1987) 2021 Jan 1;268(Pt B):115748
Environmental pollution (Barking, Essex : 1987) 2021 Jan 1;268(Pt B):115748
Oral Administration of Probiotic Bifidobacterium breve Improves Facilitation of Hippocampal Memory Extinction via Restoration of Aberrant Higher Induction of Neuropsin in an MPTP-Induced Mouse Model of Parkinson's Disease.
Ishii T, Furuoka H, Kaya M, Kuhara T
Biomedicines 2021 Feb 8;9(2)
Biomedicines 2021 Feb 8;9(2)
A novel tonicity-responsive microRNA miR-23a-5p modulates renal cell survival under osmotic stress through targeting heat shock protein 70 HSPA1B.
Kang K, Liao X, Li Q, Chen J, Niu Y, Zeng Y, Xia S, Zeng L, Liu S, Gou D
American journal of physiology. Cell physiology 2021 Feb 1;320(2):C225-C239
American journal of physiology. Cell physiology 2021 Feb 1;320(2):C225-C239
Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology.
Zhang Y, Chen X, Wang Q, Du C, Lu W, Yuan H, Zhang Z, Li D, Ling X, Ren X, Zhao Y, Su Q, Xing Z, Qin Y, Yang X, Shen Y, Wu H, Qi Y
Journal of molecular medicine (Berlin, Germany) 2021 Dec;99(12):1797-1813
Journal of molecular medicine (Berlin, Germany) 2021 Dec;99(12):1797-1813
Hypoxia-inducible factor-1α promotes proliferation of airway smooth muscle cells through miRNA-103-mediated signaling pathway under hypoxia.
Zhang C, Gao J, Zhu S
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):944-952
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):944-952
Integrated Metabolomics and Transcriptomics Analyses Reveal Metabolic Landscape in Neuronal Cells during JEV Infection.
Li M, Yang J, Ye C, Bian P, Yang X, Zhang H, Luo C, Xue Z, Lei Y, Lian J
Virologica Sinica 2021 Dec;36(6):1554-1565
Virologica Sinica 2021 Dec;36(6):1554-1565
Decreased NHE3 activity in intestinal epithelial cells in TGEV and PEDV-induced piglet diarrhea.
Niu Z, Zhang Y, Kan Z, Ran L, Yan T, Xu S, Zhang S, Zhang J, Zou H, Song Z
Veterinary microbiology 2021 Dec;263:109263
Veterinary microbiology 2021 Dec;263:109263
The STING antagonist H-151 ameliorates psoriasis via suppression of STING/NF-κB-mediated inflammation.
Pan Y, You Y, Sun L, Sui Q, Liu L, Yuan H, Chen C, Liu J, Wen X, Dai L, Sun H
British journal of pharmacology 2021 Dec;178(24):4907-4922
British journal of pharmacology 2021 Dec;178(24):4907-4922
Mbd2 deficiency alleviates retinal cell apoptosisvia the miR-345-5p/Atf1 axis in high glucoseinjury and streptozotocin-induced diabetic mice.
Ge Y, Zhang R, Feng Y, Lu J, Li H
Molecular therapy. Nucleic acids 2021 Dec 3;26:1201-1214
Molecular therapy. Nucleic acids 2021 Dec 3;26:1201-1214
HRD1-mediated METTL14 degradation regulates m(6)A mRNA modification to suppress ER proteotoxic liver disease.
Wei J, Harada BT, Lu D, Ma R, Gao B, Xu Y, Montauti E, Mani N, Chaudhuri SM, Gregory S, Weinberg SE, Zhang DD, Green R, He C, Fang D
Molecular cell 2021 Dec 16;81(24):5052-5065.e6
Molecular cell 2021 Dec 16;81(24):5052-5065.e6
TRPV4 inhibitor HC067047 produces antidepressant-like effect in LPS-induced depression mouse model.
Li W, Xu Y, Liu Z, Shi M, Zhang Y, Deng Y, Zhong X, Chen L, He J, Zeng J, Luo M, Cao W, Wan W
Neuropharmacology 2021 Dec 15;201:108834
Neuropharmacology 2021 Dec 15;201:108834
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
Liu C, Qu J, Wu M, Huang X, Li L
Ecotoxicology and environmental safety 2021 Dec 1;225:112792
Ecotoxicology and environmental safety 2021 Dec 1;225:112792
NOD2 deficiency confers a pro-tumorigenic macrophage phenotype to promote lung adenocarcinoma progression.
Wang Y, Miao Z, Qin X, Li B, Han Y
Journal of cellular and molecular medicine 2021 Aug;25(15):7545-7558
Journal of cellular and molecular medicine 2021 Aug;25(15):7545-7558
Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Ameliorate HaCaT Cell Photo-Aging.
Liu SJ, Meng MY, Han S, Gao H, Zhao YY, Yang Y, Lin ZY, Yang LR, Zhu K, Han R, Huang WW, Wang RQ, Yang LL, Wang WJ, Li L, Wang XD, Hou ZL, Liao LW, Yang L
Rejuvenation research 2021 Aug;24(4):283-293
Rejuvenation research 2021 Aug;24(4):283-293
Isoeucommin A attenuates kidney injury in diabetic nephropathy through the Nrf2/HO-1 pathway.
Huang Q, Ouyang DS, Liu Q
FEBS open bio 2021 Aug;11(8):2350-2363
FEBS open bio 2021 Aug;11(8):2350-2363
Cypermethrin induces Sertoli cell apoptosis through mitochondrial pathway associated with calcium.
Wang HX, Zhang R, Li Z, Wang LS, Yu Y, Wang Q, Ding Z, Zhang JP, Zhang MR, Xu LC
Toxicology research 2021 Aug;10(4):742-750
Toxicology research 2021 Aug;10(4):742-750
TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.
Huang D, Xu B, Liu L, Wu L, Zhu Y, Ghanbarpour A, Wang Y, Chen FJ, Lyu J, Hu Y, Kang Y, Zhou W, Wang X, Ding W, Li X, Jiang Z, Chen J, Zhang X, Zhou H, Li JZ, Guo C, Zheng W, Zhang X, Li P, Melia T, Reinisch K, Chen XW
Cell metabolism 2021 Aug 3;33(8):1655-1670.e8
Cell metabolism 2021 Aug 3;33(8):1655-1670.e8
The E2F1/USP11 positive feedback loop promotes hepatocellular carcinoma metastasis and inhibits autophagy by activating ERK/mTOR pathway.
Qiao L, Zhang Q, Sun Z, Liu Q, Wu Z, Hu W, Bao S, Yang Q, Liu L
Cancer letters 2021 Aug 28;514:63-78
Cancer letters 2021 Aug 28;514:63-78
High-Carbohydrate Diet Alleviates the Oxidative Stress, Inflammation and Apoptosis of Megalobrama amblycephala Following Dietary Exposure to Silver Nanoparticles.
Chen F, Zhao CY, Guan JF, Liu XC, Li XF, Xie DZ, Xu C
Antioxidants (Basel, Switzerland) 2021 Aug 25;10(9)
Antioxidants (Basel, Switzerland) 2021 Aug 25;10(9)
Triptolide impairs glycolysis by suppressing GATA4/Sp1/PFKP signaling axis in mouse Sertoli cells.
Zhang Y, Tang Y, Luo Y, Luo L, Shen F, Huang Z
Toxicology and applied pharmacology 2021 Aug 15;425:115606
Toxicology and applied pharmacology 2021 Aug 15;425:115606
KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathway.
Du W, Zhu J, Zeng Y, Liu T, Zhang Y, Cai T, Fu Y, Zhang W, Zhang R, Liu Z, Huang JA
Cell death and differentiation 2021 Apr;28(4):1284-1300
Cell death and differentiation 2021 Apr;28(4):1284-1300
HSP/HSC70 activity is required for Bombyx mori nucleopolyhedrovirus replication at the early infectious phase.
Mao F, Zhu Y, Gao X, Chen X, Ngowo J, Miao M, Quan Y, Yu W
Microbial pathogenesis 2021 Apr;153:104647
Microbial pathogenesis 2021 Apr;153:104647
Salidroside Attenuates Doxorubicin-Induced Cardiac Dysfunction Partially Through Activation of QKI/FoxO1 Pathway.
Yan F, Liu R, Zhuang X, Li R, Shi H, Gao X
Journal of cardiovascular translational research 2021 Apr;14(2):355-364
Journal of cardiovascular translational research 2021 Apr;14(2):355-364
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1.
Yang F, Zhang Y, Zhu J, Wang J, Jiang Z, Zhao C, Yang Q, Huang Y, Yao W, Pang W, Han L, Zhou J
Frontiers in bioengineering and biotechnology 2020;8:647
Frontiers in bioengineering and biotechnology 2020;8:647
Neural Tube Defects and ZIC4 Hypomethylation in Relation to Polycyclic Aromatic Hydrocarbon Exposure.
Huang Y, Lin S, Wang C, Pi X, Jin L, Li Z, Wang L, Ren A
Frontiers in cell and developmental biology 2020;8:582661
Frontiers in cell and developmental biology 2020;8:582661
Identification of Transcriptional Variation in Aortic Remodeling Using a Murine Transverse Aortic Constriction (TAC) Model.
Zhang X, Feng T, Zeng XI, Liang H, Situ B, Zhang Q, Zhou F, Chen Y, Wang T, Cai D, Lin X, Xiu J, Zheng L
Frontiers in cardiovascular medicine 2020;7:581362
Frontiers in cardiovascular medicine 2020;7:581362
Similar Repair Effects of Human Placenta, Bone Marrow Mesenchymal Stem Cells, and Their Exosomes for Damaged SVOG Ovarian Granulosa Cells.
Chen S, Wang Y, Liao L, Meng L, Li J, Shi C, Han H, Zheng X, Shen H
Stem cells international 2020;2020:8861557
Stem cells international 2020;2020:8861557
Beneficial Effects of Crocin against Depression via Pituitary Adenylate Cyclase-Activating Polypeptide.
Lu L, Wu D, Wang K, Tang J, Chen G
BioMed research international 2020;2020:3903125
BioMed research international 2020;2020:3903125
Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway.
Gao W, Feng Z, Zhang S, Wu B, Geng X, Fan G, Duan Y, Li K, Liu K, Peng C
BioMed research international 2020;2020:1860637
BioMed research international 2020;2020:1860637
Skp2 modulates proliferation, senescence and tumorigenesis of glioma.
Wu J, Su HK, Yu ZH, Xi SY, Guo CC, Hu ZY, Qu Y, Cai HP, Zhao YY, Zhao HF, Chen FR, Huang YF, To ST, Feng BH, Sai K, Chen ZP, Wang J
Cancer cell international 2020;20:71
Cancer cell international 2020;20:71
HCK can serve as novel prognostic biomarker and therapeutic target for Breast Cancer patients.
Zhu X, Zhang Y, Bai Y, Gu X, Chen G, Sun L, Wang Y, Qiao X, Ma Q, Zhu T, Bu J, Xue J, Liu C
International journal of medical sciences 2020;17(17):2773-2789
International journal of medical sciences 2020;17(17):2773-2789
Repression of FGF signaling is responsible for Dnmt3b inhibition and impaired de novo DNA methylation during early development of in vitro fertilized embryos.
Fu W, Yue Y, Miao K, Xi G, Zhang C, Wang W, An L, Tian J
International journal of biological sciences 2020;16(15):3085-3099
International journal of biological sciences 2020;16(15):3085-3099
G Protein-Coupled Receptor 109A Maintains the Intestinal Integrity and Protects Against ETEC Mucosal Infection by Promoting IgA Secretion.
Gong Y, Jin X, Yuan B, Lv Y, Yan G, Liu M, Xie C, Liu J, Tang Y, Gao H, Zhu Y, Huang Y, Wang W
Frontiers in immunology 2020;11:583652
Frontiers in immunology 2020;11:583652
Integration of Transcriptomics and Metabolomics Reveals the Antitumor Mechanism Underlying Shikonin in Colon Cancer.
Chen Y, Gao Y, Yi X, Zhang J, Chen Z, Wu Y
Frontiers in pharmacology 2020;11:544647
Frontiers in pharmacology 2020;11:544647
Possible Roles of Proinflammatory Signaling in Keratinocytes Through Aryl Hydrocarbon Receptor Ligands for the Development of Squamous Cell Carcinoma.
Sato Y, Fujimura T, Hidaka T, Lyu C, Tanita K, Matsushita S, Yamamoto M, Aiba S
Frontiers in immunology 2020;11:534323
Frontiers in immunology 2020;11:534323
Cyclophilin A plays an important role in embryo implantation through activating Stat3.
Yu T, Lin S, Xu R, Du TX, Li Y, Gao H, Diao HL, Zhang XH
Reproduction (Cambridge, England) 2020 Sep;160(3):343-351
Reproduction (Cambridge, England) 2020 Sep;160(3):343-351
Control the fate of human umbilical cord mesenchymal stem cells with dual-enzymatically cross-linked gelatin hydrogels for potential applications in nerve regeneration.
Li J, Gao F, Ma S, Zhang Y, Zhang J, Guan F, Yao M
Journal of tissue engineering and regenerative medicine 2020 Sep;14(9):1261-1271
Journal of tissue engineering and regenerative medicine 2020 Sep;14(9):1261-1271
miR-361-5p Mediates SMAD4 to Promote Porcine Granulosa Cell Apoptosis through VEGFA.
Ma M, Zhang J, Gao X, Yao W, Li Q, Pan Z
Biomolecules 2020 Sep 4;10(9)
Biomolecules 2020 Sep 4;10(9)
Neddylation promotes protein translocation between the cytoplasm and nucleus.
Li S, Fang W, Cui Y, Shi H, Chen J, Li L, Zhang L, Zhang X
Biochemical and biophysical research communications 2020 Sep 3;529(4):991-997
Biochemical and biophysical research communications 2020 Sep 3;529(4):991-997
EPS8 regulates an NLRP3 inflammasome-independent caspase-1 activation pathway in monosodium urate crystal-treated RAW264.7 macrophages.
Chuang JP, Kao CY, Lee JC, Ling P, Maa MC, Leu TH
Biochemical and biophysical research communications 2020 Sep 24;530(3):487-493
Biochemical and biophysical research communications 2020 Sep 24;530(3):487-493
RNA-binding protein CUGBP1 controls the differential INSR splicing in molecular subtypes of breast cancer cells and affects cell aggressiveness.
Huang G, Song C, Wang N, Qin T, Sui S, Obr A, Zeng L, Wood TL, Leroith D, Li M, Wu Y
Carcinogenesis 2020 Sep 24;41(9):1294-1305
Carcinogenesis 2020 Sep 24;41(9):1294-1305
Chrysin Inhibits Melanoma Tumor Metastasis via Interfering with the FOXM1/β-Catenin Signaling.
Yufei Z, Yuqi W, Binyue H, Lingchen T, Xi C, Hoffelt D, Fuliang H
Journal of agricultural and food chemistry 2020 Sep 2;68(35):9358-9367
Journal of agricultural and food chemistry 2020 Sep 2;68(35):9358-9367
Indole alkaloids from leaves of Alstonia scholaris (L.) R. Br. protect against emphysema in mice.
Zhao YL, Yang ZF, Wu BF, Shang JH, Liu YP, Wang XH, Luo XD
Journal of ethnopharmacology 2020 Sep 15;259:112949
Journal of ethnopharmacology 2020 Sep 15;259:112949
miR-203 inhibits cell proliferation and ERK pathway in prostate cancer by targeting IRS-1.
Meng Y, Hu X, Li S, Zeng X, Qiu L, Wei M, Wang Z, Han J
BMC cancer 2020 Oct 27;20(1):1028
BMC cancer 2020 Oct 27;20(1):1028
Identification of long-term survival-associated gene in breast cancer.
Ning S, Li H, Qiao K, Wang Q, Shen M, Kang Y, Yin Y, Liu J, Liu L, Hou S, Wang J, Xu S, Pang D
Aging 2020 Oct 20;12(20):20332-20349
Aging 2020 Oct 20;12(20):20332-20349
bta-miR-23a Regulates the Myogenic Differentiation of Fetal Bovine Skeletal Muscle-Derived Progenitor Cells by Targeting MDFIC Gene.
Hu X, Xing Y, Ren L, Wang Y, Li Q, Yang Q, Du M, Xu L, Willems L, Li J, Zhang L
Genes 2020 Oct 20;11(10)
Genes 2020 Oct 20;11(10)
Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage.
Fan C, Feng J, Tang C, Zhang Z, Feng Y, Duan W, Zhai M, Yan Z, Zhu L, Feng L, Zhu H, Luo E
Stem cell research & therapy 2020 Oct 15;11(1):442
Stem cell research & therapy 2020 Oct 15;11(1):442
Efficacy of a wound-dressing biomaterial on prevention of postinflammatory hyperpigmentation after suction blister epidermal grafting in stable vitiligo patients: a controlled assessor-blinded clinical study with in vitro bioactivity investigation.
Liu Z, Jiang M, Zhao J, Wang Q, Zhang C, Gao M, Gu M, Xiang L
Archives of dermatological research 2020 Nov;312(9):635-645
Archives of dermatological research 2020 Nov;312(9):635-645
The critical role of the hippocampal NLRP3 inflammasome in social isolation-induced cognitive impairment in male mice.
Niu L, Luo SS, Xu Y, Wang Z, Luo D, Yang H, Li W, He J, Zhong XL, Liu ZH, Zeng JY, Cao WY, Wan W
Neurobiology of learning and memory 2020 Nov;175:107301
Neurobiology of learning and memory 2020 Nov;175:107301
MitoQ attenuates brain damage by polarizing microglia towards the M2 phenotype through inhibition of the NLRP3 inflammasome after ICH.
Chen W, Guo C, Huang S, Jia Z, Wang J, Zhong J, Ge H, Yuan J, Chen T, Liu X, Hu R, Yin Y, Feng H
Pharmacological research 2020 Nov;161:105122
Pharmacological research 2020 Nov;161:105122
The B7-H4 gene induces immune escape partly via upregulating the PD-1/Stat3 pathway in non-small cell lung cancer.
Yuan L, Ye J, Fan D
Human immunology 2020 May;81(5):254-261
Human immunology 2020 May;81(5):254-261
Protein target identification of ginsenosides in skeletal muscle tissues: discovery of natural small-molecule activators of muscle-type creatine kinase.
Chen F, Zhu K, Chen L, Ouyang L, Chen C, Gu L, Jiang Y, Wang Z, Lin Z, Zhang Q, Shao X, Dai J, Zhao Y
Journal of ginseng research 2020 May;44(3):461-474
Journal of ginseng research 2020 May;44(3):461-474
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, Shao X, Song N, Zhao Y, Li H, Yang G, Xu C, Wei C
Redox biology 2020 May;32:101514
Redox biology 2020 May;32:101514
Leptin mediates protection of hydrogen sulfide against 6-hydroxydopamine-induced Parkinson's disease: Involving enhancement in Warburg effect.
Yang SQ, Tian Q, Li D, He SQ, Hu M, Liu SY, Zou W, Chen YJ, Zhang P, Tang XQ
Neurochemistry international 2020 May;135:104692
Neurochemistry international 2020 May;135:104692
Neuropeptide Y1 receptor antagonist promotes osteoporosis and microdamage repair and enhances osteogenic differentiation of bone marrow stem cells via cAMP/PKA/CREB pathway.
Xie W, Li F, Han Y, Qin Y, Wang Y, Chi X, Xiao J, Li Z
Aging 2020 May 7;12(9):8120-8136
Aging 2020 May 7;12(9):8120-8136
A Novel Mechanism of bta-miR-210 in Bovine Early Intramuscular Adipogenesis.
Ren L, Li Q, Hu X, Yang Q, Du M, Xing Y, Wang Y, Li J, Zhang L
Genes 2020 May 29;11(6)
Genes 2020 May 29;11(6)
Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep.
Zhang R, Li Y, Jia K, Xu X, Li Y, Zhao Y, Zhang X, Zhang J, Liu G, Deng S, Lian Z
Cell death & disease 2020 May 29;11(5):407
Cell death & disease 2020 May 29;11(5):407
Synergistic antifibrotic effects of miR-451 with miR-185 partly by co-targeting EphB2 on hepatic stellate cells.
Chen X, Zhang D, Wang Y, Chen K, Zhao L, Xu Y, Jiang H, Wang S
Cell death & disease 2020 May 28;11(5):402
Cell death & disease 2020 May 28;11(5):402
Synthesis and biological evaluations of N'-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents.
Li B, Zhu F, He F, Huang Q, Liu X, Wu T, Zhao T, Qiu Y, Wu Z, Xue Y, Fang M
Bioorganic chemistry 2020 Mar;96:103592
Bioorganic chemistry 2020 Mar;96:103592
Mbd2 Mediates Retinal Cell Apoptosis by Targeting the lncRNA Mbd2-AL1/miR-188-3p/Traf3 Axis in Ischemia/Reperfusion Injury.
Ge Y, Zhang R, Feng Y, Li H
Molecular therapy. Nucleic acids 2020 Mar 6;19:1250-1265
Molecular therapy. Nucleic acids 2020 Mar 6;19:1250-1265
Anti-neuroinflammatory effect of 3,4-dihydroxybenzaldehyde in ischemic stroke.
Li X, Xiang B, Shen T, Xiao C, Dai R, He F, Lin Q
International immunopharmacology 2020 Mar 3;82:106353
International immunopharmacology 2020 Mar 3;82:106353
Yueju-Ganmaidazao Decoction confers rapid antidepressant-like effects and the involvement of suppression of NMDA/NO/cGMP signaling.
Zhang H, Sun Y, Qian S, Ge R, Guo X, Shen Q, Sheng L, Nie C, Zhang Y, Yao Y, Zhou T, Wang W, Xue W, Chen G
Journal of ethnopharmacology 2020 Mar 25;250:112380
Journal of ethnopharmacology 2020 Mar 25;250:112380
The developmental and experience-dependent expression of IGF-2 in mice visual cortex.
Luo Y, Liu Z, Luo S, Wang X, Tao L
Neuroscience letters 2020 Mar 16;721:134828
Neuroscience letters 2020 Mar 16;721:134828
Overexpression of NRF1-742 or NRF1-772 Reduces Arsenic-Induced Cytotoxicity and Apoptosis in Human HaCaT Keratinocytes.
Wang S, Cheng H, Wang L, Zhao R, Guan D
International journal of molecular sciences 2020 Mar 16;21(6)
International journal of molecular sciences 2020 Mar 16;21(6)
Circular RNA hsa_circ_0008285 inhibits colorectal cancer cell proliferation and migration via the miR-382-5p/PTEN axis.
Wang J, Luo J, Liu G, Li X
Biochemical and biophysical research communications 2020 Jun 25;527(2):503-510
Biochemical and biophysical research communications 2020 Jun 25;527(2):503-510
Hepatic HuR modulates lipid homeostasis in response to high-fat diet.
Zhang Z, Zong C, Jiang M, Hu H, Cheng X, Ni J, Yi X, Jiang B, Tian F, Chang MW, Su W, Zhu L, Li J, Xiang X, Miao C, Gorospe M, de Cabo R, Dou Y, Ju Z, Yang J, Jiang C, Yang Z, Wang W
Nature communications 2020 Jun 16;11(1):3067
Nature communications 2020 Jun 16;11(1):3067
Melatonin regulates mitochondrial dynamics and alleviates neuron damage in prion diseases.
Zhang X, Zhao D, Wu W, Ali Shah SZ, Lai M, Yang D, Li J, Guan Z, Li W, Gao H, Zhao H, Zhou X, Yang L
Aging 2020 Jun 10;12(11):11139-11151
Aging 2020 Jun 10;12(11):11139-11151
PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition.
Dong P, Fu H, Chen L, Zhang S, Zhang X, Li H, Wu D, Ji X
Journal of cellular and molecular medicine 2020 Jul;24(14):8221-8235
Journal of cellular and molecular medicine 2020 Jul;24(14):8221-8235
A novel microRNA and its pfk target control growth length in the freshwater shrimp Neocaridina heteropoda.
Li R, Weng J, Ren L, Wang X, Meng Q, Wang L, Sun J
The Journal of experimental biology 2020 Jul 8;223(Pt 13)
The Journal of experimental biology 2020 Jul 8;223(Pt 13)
Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5.
Wang Y, Zhang X, Chen W, Gao L, Li J, Song T, Chi J, Zhang X, Shi Z, Dong Y, Yin X, Liu Y
Life sciences 2020 Jul 15;253:117726
Life sciences 2020 Jul 15;253:117726
Nucleus-located PDK1 regulates growth, invasion and migration of breast cancer cells.
Gan D, Yue S, Jiang Y, Zhang D, Shi H, Qian H, Zhou T, Fang W, Yao M, Zuo G, Chen T
Life sciences 2020 Jul 15;253:117722
Life sciences 2020 Jul 15;253:117722
Autophagy inducer activates Nrf2-ARE pathway to attenuate aberrant alveolarization in neonatal rats with bronchopulmonary dysplasia.
Zhao X, Shi Y, Zhang D, Tong X, Sun Y, Xue X, Fu J
Life sciences 2020 Jul 1;252:117662
Life sciences 2020 Jul 1;252:117662
PCNA and GSK3β interact with each other to regulate H1299 lung adenocarcinoma cells apoptosis.
Liu XH, Tang DE, Dai Y, Gao XJ, Liu LX
Neoplasma 2020 Jan;67(1):15-26
Neoplasma 2020 Jan;67(1):15-26
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Jiang YP, Ye RJ, Yang JM, Liu N, Zhang WJ, Ma L, Sun T, Niu JG, Zheng P, Yu JQ
Chemico-biological interactions 2020 Jan 5;315:108869
Chemico-biological interactions 2020 Jan 5;315:108869
Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis.
Feng J, Dai W, Mao Y, Wu L, Li J, Chen K, Yu Q, Kong R, Li S, Zhang J, Ji J, Wu J, Mo W, Xu X, Guo C
Journal of experimental & clinical cancer research : CR 2020 Jan 30;39(1):24
Journal of experimental & clinical cancer research : CR 2020 Jan 30;39(1):24
SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1-STAT3 Signaling in Human ES Cells.
Cai BH, Lee HY, Chou CK, Wu PH, Huang HC, Chao CC, Chung HY, Kannagi R
Cells 2020 Jan 10;9(1)
Cells 2020 Jan 10;9(1)
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA(2) phosphorylation in experimental ischemic stroke.
Cao C, Zhou J, Wu X, Qian Y, Hong Y, Mu J, Jin L, Zhu C, Li S
Cellular signalling 2020 Feb;66:109467
Cellular signalling 2020 Feb;66:109467
Pizotifen inhibits the proliferation and invasion of gastric cancer cells.
Jiang Y, Wang W, Wu X, Shi J
Experimental and therapeutic medicine 2020 Feb;19(2):817-824
Experimental and therapeutic medicine 2020 Feb;19(2):817-824
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABA(A) receptors.
Teoh J, Subramanian N, Pero ME, Bartolini F, Amador A, Kanber A, Williams D, Petri S, Yang M, Allen AS, Beal J, Haut SR, Frankel WN
Neurobiology of disease 2020 Feb;134:104632
Neurobiology of disease 2020 Feb;134:104632
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma.
Ding XY, Hu HY, Huang KN, Wei RQ, Min J, Qi C, Tang H, Qin X
Cancer science 2020 Feb;111(2):489-501
Cancer science 2020 Feb;111(2):489-501
NCAPG Dynamically Coordinates the Myogenesis of Fetal Bovine Tissue by Adjusting Chromatin Accessibility.
Hu X, Xing Y, Fu X, Yang Q, Ren L, Wang Y, Li Q, Li J, Zhang L
International journal of molecular sciences 2020 Feb 13;21(4)
International journal of molecular sciences 2020 Feb 13;21(4)
Sodium butyrate causes α-synuclein degradation by an Atg5-dependent and PI3K/Akt/mTOR-related autophagy pathway.
Qiao CM, Sun MF, Jia XB, Shi Y, Zhang BP, Zhou ZL, Zhao LP, Cui C, Shen YQ
Experimental cell research 2020 Feb 1;387(1):111772
Experimental cell research 2020 Feb 1;387(1):111772
Oxidative stress-mediated hepatotoxicity in rats induced by ethanol extracts of different parts of Chloranthus serratus.
Sun S, Wang Y, Du Y, Sun Q, He L, Zhu E, Li J
Pharmaceutical biology 2020 Dec;58(1):1277-1289
Pharmaceutical biology 2020 Dec;58(1):1277-1289
Regulation of indoleamine 2, 3-dioxygenase in hippocampal microglia by NLRP3 inflammasome in lipopolysaccharide-induced depressive-like behaviors.
Zhang S, Zong Y, Ren Z, Hu J, Wu X, Xiao H, Qin S, Zhou G, Ma Y, Zhang Y, Yu J, Wang K, Lu G, Liu Q
The European journal of neuroscience 2020 Dec;52(11):4586-4601
The European journal of neuroscience 2020 Dec;52(11):4586-4601
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
Chen M, Ding Y, Ke Y, Zeng Y, Liu N, Zhong Y, Hua X, Li Z, Xiong Y, Wu C, Yu H
Artificial cells, nanomedicine, and biotechnology 2020 Dec;48(1):824-833
Artificial cells, nanomedicine, and biotechnology 2020 Dec;48(1):824-833
IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2.
Wang Z, Qi Y, Wang R, Wu W, Li Z, Wang M, Liu R, Zhang C, Li W, Wang S
Journal of cellular physiology 2020 Dec;235(12):9538-9556
Journal of cellular physiology 2020 Dec;235(12):9538-9556
Inhibition of p38 MAPK regulates epileptic severity by decreasing expression levels of A1R and ENT1.
Zhou X, Chen Q, Huang H, Zhang J, Wang J, Chen Y, Peng Y, Zhang H, Zeng J, Feng Z, Xu Z
Molecular medicine reports 2020 Dec;22(6):5348-5357
Molecular medicine reports 2020 Dec;22(6):5348-5357
Tongmai formula improves cardiac function via regulating mitochondrial quality control in the myocardium with ischemia/reperfusion injury.
Zhao Y, Guo R, Li L, Li S, Fan G, Zhao X, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110897
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110897
Radiosensitization Effect of AGuIX, a Gadolinium-Based Nanoparticle, in Nonsmall Cell Lung Cancer.
Du Y, Sun H, Lux F, Xie Y, Du L, Xu C, Zhang H, He N, Wang J, Liu Y, Leduc G, Doussineau T, Ji K, Wang Q, Lin Z, Wang Y, Liu Q, Tillement O
ACS applied materials & interfaces 2020 Dec 23;12(51):56874-56885
ACS applied materials & interfaces 2020 Dec 23;12(51):56874-56885
Adiponectin protects HL-1 cardiomyocytes against rotenone-induced cytotoxicity through AMPK activation.
Li B, Zhang B, Liu N, Wu K, Ma Y, Zuo W, Ning Z, Liu Y, Sun C, Xiao Y, Tu T, Liu Q
Toxicology letters 2020 Dec 15;335:82-90
Toxicology letters 2020 Dec 15;335:82-90
Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.
Li Y, Bai L, Yu H, Cai D, Wang X, Huang B, Peng S, Huang M, Cao G, Kaz AM, Grady WM, Wang J, Luo Y
Cancer research 2020 Dec 1;80(23):5203-5215
Cancer research 2020 Dec 1;80(23):5203-5215
Blood coagulation factor VIII D1241E polymorphism leads to a weak malectin interaction and reduction of factor VIII posttranslational modification and secretion.
Jiang N, Xiao Y, Liu Y, Liu W, Liu S
Experimental cell research 2020 Dec 1;397(1):112334
Experimental cell research 2020 Dec 1;397(1):112334
Homocysteine downregulates cardiac homeobox transcription factor NKX2.5 via IGFBP5.
Lai G, Wang L, Li Z, Zhao Y
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1380-H1386
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1380-H1386
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Yang YX, Yu S, Jia BX, Liu N, Wu A
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Interplay of m(6)A and H3K27 trimethylation restrains inflammation during bacterial infection.
Wu C, Chen W, He J, Jin S, Liu Y, Yi Y, Gao Z, Yang J, Yang J, Cui J, Zhao W
Science advances 2020 Aug;6(34):eaba0647
Science advances 2020 Aug;6(34):eaba0647
WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy.
Zhang Y, You S, Tian Y, Lu S, Cao L, Sun Y, Zhang N
Journal of cellular and molecular medicine 2020 Aug;24(16):9041-9054
Journal of cellular and molecular medicine 2020 Aug;24(16):9041-9054
Myricetin ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting TGF-β signaling via targeting HSP90β.
Li X, Yu H, Liang L, Bi Z, Wang Y, Gao S, Wang M, Li H, Miao Y, Deng R, Ma L, Luan J, Li S, Liu M, Lin J, Zhou H, Yang C
Biochemical pharmacology 2020 Aug;178:114097
Biochemical pharmacology 2020 Aug;178:114097
Lnc-M2 controls M2 macrophage differentiation via the PKA/CREB pathway.
Chen Y, Li H, Ding T, Li J, Zhang Y, Wang J, Yang X, Chong T, Long Y, Li X, Gao F, Lyu X
Molecular immunology 2020 Aug;124:142-152
Molecular immunology 2020 Aug;124:142-152
Anti-Inflammatory Effect of Simonsinol on Lipopolysaccharide Stimulated RAW264.7 Cells through Inactivation of NF-κB Signaling Pathway.
Li LC, Pan ZH, Ning DS, Fu YX
Molecules (Basel, Switzerland) 2020 Aug 6;25(16)
Molecules (Basel, Switzerland) 2020 Aug 6;25(16)
Precise base editing with CC context-specificity using engineered human APOBEC3G-nCas9 fusions.
Liu Z, Chen S, Shan H, Jia Y, Chen M, Song Y, Lai L, Li Z
BMC biology 2020 Aug 31;18(1):111
BMC biology 2020 Aug 31;18(1):111
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Zou YJ, Xu JJ, Wang X, Zhu YH, Wu Q, Wang JF
Veterinary sciences 2020 Aug 14;7(3)
Veterinary sciences 2020 Aug 14;7(3)
Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.
Harmouch E, Seitlinger J, Chaddad H, Ubeaud-Sequier G, Barths J, Saidu S, Désaubry L, Grandemange S, Massfelder T, Fuhrmann G, Fioretti F, Dontenwill M, Benkirane-Jessel N, Idoux-Gillet Y
Scientific reports 2020 Aug 13;10(1):13750
Scientific reports 2020 Aug 13;10(1):13750
Design, synthesis and biological evaluation of a novel tubulin inhibitor SKLB0565 targeting the colchicine binding site.
Hu X, Li L, Zhang Q, Wang Q, Feng Z, Xu Y, Xia Y, Yu L
Bioorganic chemistry 2020 Apr;97:103695
Bioorganic chemistry 2020 Apr;97:103695
Hypoxia induces tumor cell growth and angiogenesis in non-small cell lung carcinoma via the Akt-PDK1-HIF1α-YKL-40 pathway.
Miao Y, Wang W, Dong Y, Hu J, Wei K, Yang S, Lai X, Tang H
Translational cancer research 2020 Apr;9(4):2904-2918
Translational cancer research 2020 Apr;9(4):2904-2918
The E3 ubiquitin ligase Smurf2 regulates PARP1 stability to alleviate oxidative stress-induced injury in human umbilical vein endothelial cells.
Qian H, Zhang N, Wu B, Wu S, You S, Zhang Y, Sun Y
Journal of cellular and molecular medicine 2020 Apr;24(8):4600-4611
Journal of cellular and molecular medicine 2020 Apr;24(8):4600-4611
Monophosphoryl lipid A alleviated radiation-induced testicular injury through TLR4-dependent exosomes.
Liu Z, Cao K, Liao Z, Chen Y, Lei X, Wei Q, Liu C, Sun X, Yang Y, Cai J, Gao F
Journal of cellular and molecular medicine 2020 Apr;24(7):3917-3930
Journal of cellular and molecular medicine 2020 Apr;24(7):3917-3930
Inhibition of histone acetyltransferase GCN5 extends lifespan in both yeast and human cell lines.
Huang B, Zhong D, Zhu J, An Y, Gao M, Zhu S, Dang W, Wang X, Yang B, Xie Z
Aging cell 2020 Apr;19(4):e13129
Aging cell 2020 Apr;19(4):e13129
The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity.
Peng H, Yang F, Hu Q, Sun J, Peng C, Zhao Y, Huang C
Autophagy 2020 Apr;16(4):698-708
Autophagy 2020 Apr;16(4):698-708
Exogenous H(2)S Induces Hrd1 S-sulfhydration and Prevents CD36 Translocation via VAMP3 Ubiquitylation in Diabetic Hearts.
Yu M, Du H, Wang B, Chen J, Lu F, Peng S, Sun Y, Liu N, Sun X, Shiyun D, Zhao Y, Wang Y, Zhao D, Lu F, Zhang W
Aging and disease 2020 Apr;11(2):286-300
Aging and disease 2020 Apr;11(2):286-300
Systemic MCPIP1 deficiency in mice impairs lipid homeostasis.
Moody J, Yang C, Sedinkin J, Chang Y
Current research in pharmacology and drug discovery 2020 Apr;1:1-9
Current research in pharmacology and drug discovery 2020 Apr;1:1-9
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
Chen Z, Yuan SJ, Li K, Zhang Q, Li TF, An HC, Xu HZ, Yue Y, Han M, Xu YH, Komatsu N, Zhao L, Chen X
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
Xie C, Zhu J, Jiang Y, Chen J, Wang X, Geng S, Wu J, Zhong C, Li X, Meng Z
Theranostics 2019;9(16):4827-4840
Theranostics 2019;9(16):4827-4840
BH3 mimetic ABT-263 enhances the anticancer effects of apigenin in tumor cells with activating EGFR mutation.
Zhan Y, Wang Y, Qi M, Liang P, Ma Y, Li T, Li H, Dai C, An Z, Qi Y, Wu H, Shao H
Cell & bioscience 2019;9:60
Cell & bioscience 2019;9:60
The Binding of PD-L1 and Akt Facilitates Glioma Cell Invasion Upon Starvation via Akt/Autophagy/F-Actin Signaling.
Chen RQ, Xu XH, Liu F, Li CY, Li YJ, Li XR, Jiang GY, Hu F, Liu D, Pan F, Qiu XY, Chen XQ
Frontiers in oncology 2019;9:1347
Frontiers in oncology 2019;9:1347
Neuroprotective Effect of Echinacoside in Subacute Mouse Model of Parkinson's Disease.
Liang Y, Chen C, Xia B, Wu W, Tang J, Chen Q, Tang L, Yang H, Zhang Z, Lu Y, Yang Y, Zhao Y
BioMed research international 2019;2019:4379639
BioMed research international 2019;2019:4379639
Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1).
Zhang C, Wang B, Wang X, Sheng X, Cui Y
Cancer cell international 2019;19:339
Cancer cell international 2019;19:339
(-)-Epigallocatechin-3-gallate derivatives combined with cisplatin exhibit synergistic inhibitory effects on non-small-cell lung cancer cells.
Wang J, Sun P, Wang Q, Zhang P, Wang Y, Zi C, Wang X, Sheng J
Cancer cell international 2019;19:266
Cancer cell international 2019;19:266
Long-Term Effects of Zinc Deficiency and Zinc Supplementation on Developmental Seizure-Induced Brain Damage and the Underlying GPR39/ZnT-3 and MBP Expression in the Hippocampus.
Chen NN, Zhao DJ, Sun YX, Wang DD, Ni H
Frontiers in neuroscience 2019;13:920
Frontiers in neuroscience 2019;13:920
Catalpol prevents denervated muscular atrophy related to the inhibition of autophagy and reduces BAX/BCL2 ratio via mTOR pathway.
Wang Y, Shao Y, Gao Y, Wan G, Wan D, Zhu H, Qiu Y, Ye X
Drug design, development and therapy 2019;13:243-253
Drug design, development and therapy 2019;13:243-253
Lipoxin A4 Regulates Lipopolysaccharide-Induced BV2 Microglial Activation and Differentiation via the Notch Signaling Pathway.
Wu J, Ding DH, Li QQ, Wang XY, Sun YY, Li LJ
Frontiers in cellular neuroscience 2019;13:19
Frontiers in cellular neuroscience 2019;13:19
Protein kinase C-iota-mediated glycolysis promotes non-small-cell lung cancer progression.
Liu L, Lei B, Wang L, Chang C, Yang H, Liu J, Huang G, Xie W
OncoTargets and therapy 2019;12:5835-5848
OncoTargets and therapy 2019;12:5835-5848
LXRα Promotes the Differentiation of Human Gastric Cancer Cells through Inactivation of Wnt/β-catenin Signaling.
Gao Y, Chen Z, Wang R, Tan X, Huang C, Chen G, Chen Z
Journal of Cancer 2019;10(1):156-167
Journal of Cancer 2019;10(1):156-167
A Comparative Peptidomic Characterization of Cultured Skeletal Muscle Tissues Derived From db/db Mice.
Wu Y, Han M, Wang Y, Gao Y, Cui X, Xu P, Ji C, Zhong T, You L, Zeng Y
Frontiers in endocrinology 2019;10:741
Frontiers in endocrinology 2019;10:741
TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease.
Wang Y, Zhu X, Yuan S, Wen S, Liu X, Wang C, Qu Z, Li J, Liu H, Sun L, Liu F
Frontiers in endocrinology 2019;10:603
Frontiers in endocrinology 2019;10:603
An improved Tet-on system in microRNA overexpression and CRISPR/Cas9-mediated gene editing.
Kang K, Huang L, Li Q, Liao X, Dang Q, Yang Y, Luo J, Zeng Y, Li L, Gou D
Journal of animal science and biotechnology 2019;10:43
Journal of animal science and biotechnology 2019;10:43
Anti-TGEV Miller Strain Infection Effect of Lactobacillus plantarum Supernatant Based on the JAK-STAT1 Signaling Pathway.
Wang K, Ran L, Yan T, Niu Z, Kan Z, Zhang Y, Yang Y, Xie L, Huang S, Yu Q, Wu D, Song Z
Frontiers in microbiology 2019;10:2540
Frontiers in microbiology 2019;10:2540
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Wang Y, Zhao S, Chen Y, Wang T, Dong C, Wo X, Zhang J, Dong Y, Xu W, Feng X, Qu C, Wang Y, Zhong Z, Zhao W
Frontiers in microbiology 2019;10:1633
Frontiers in microbiology 2019;10:1633
Integrating yeast chemical genomics and mammalian cell pathway analysis.
Zhou FL, Li SC, Zhu Y, Guo WJ, Shao LJ, Nelson J, Simpkins S, Yang DH, Liu Q, Yashiroda Y, Xu JB, Fan YY, Yue JM, Yoshida M, Xia T, Myers CL, Boone C, Wang MW
Acta pharmacologica Sinica 2019 Sep;40(9):1245-1255
Acta pharmacologica Sinica 2019 Sep;40(9):1245-1255
Sorafenib kills liver cancer cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids via the ATP-AMPK-mTOR-SREBP1 signaling pathway.
Liu G, Kuang S, Cao R, Wang J, Peng Q, Sun C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10089-10103
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10089-10103
The oncogenic role of CB2 in the progression of non-small-cell lung cancer.
Xu S, Ma H, Bo Y, Shao M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109080
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109080
Interactions between β-cyclodextrin and tea catechins, and potential anti-osteoclastogenesis activity of the (-)-epigallocatechin-3-gallate-β-cyclodextrin complex.
Xu H, Liu T, Xu J, Li J, Chen F, Xiang Z, Huang Y, Zhang D, Hu L, Zhang B, Zi C, Wang X, Sheng J
RSC advances 2019 Sep 3;9(48):28006-28018
RSC advances 2019 Sep 3;9(48):28006-28018
Exosomal transfer of miR-501 confers doxorubicin resistance and tumorigenesis via targeting of BLID in gastric cancer.
Liu X, Lu Y, Xu Y, Hou S, Huang J, Wang B, Zhao J, Xia S, Fan S, Yu X, Du Y, Hou L, Li Z, Ding Z, An S, Huang B, Li L, Tang J, Ju J, Guan H, Song B
Cancer letters 2019 Sep 10;459:122-134
Cancer letters 2019 Sep 10;459:122-134
USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway.
Sun H, Ou B, Zhao S, Liu X, Song L, Liu X, Wang R, Peng Z
EBioMedicine 2019 Oct;48:236-247
EBioMedicine 2019 Oct;48:236-247
Deregulated lncRNA expression profile in the mouse lung adenocarcinomas with KRAS-G12D mutation and P53 knockout.
Zhang M, Jiang N, Cui R, Du S, Ou H, Chen T, Ge R, Ma D, Zhang J
Journal of cellular and molecular medicine 2019 Oct;23(10):6978-6988
Journal of cellular and molecular medicine 2019 Oct;23(10):6978-6988
Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and hippocampi of adolescent mice.
Buck JM, O'Neill HC, Stitzel JA
Biochemical pharmacology 2019 Oct;168:438-451
Biochemical pharmacology 2019 Oct;168:438-451
Oxidation derivative of (-)-epigallocatechin-3-gallate (EGCG) inhibits RANKL-induced osteoclastogenesis by suppressing RANK signaling pathways in RAW 264.7 cells.
Xu H, Liu T, Li J, Xu J, Chen F, Hu L, Zhang B, Zi C, Wang X, Sheng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109237
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109237
HIF-1α contributes to Ang II-induced inflammatory cytokine production in podocytes.
Huang H, Fan Y, Gao Z, Wang W, Shao N, Zhang L, Yang Y, Zhu W, Chen Z, Hu J, Ding G
BMC pharmacology & toxicology 2019 Oct 17;20(1):59
BMC pharmacology & toxicology 2019 Oct 17;20(1):59
The CRISPR-Cas13a Gene-Editing System Induces Collateral Cleavage of RNA in Glioma Cells.
Wang Q, Liu X, Zhou J, Yang C, Wang G, Tan Y, Wu Y, Zhang S, Yi K, Kang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2019 Oct 16;6(20):1901299
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2019 Oct 16;6(20):1901299
An LTR retrotransposon-derived lncRNA interacts with RNF169 to promote homologous recombination.
Deng B, Xu W, Wang Z, Liu C, Lin P, Li B, Huang Q, Yang J, Zhou H, Qu L
EMBO reports 2019 Nov 5;20(11):e47650
EMBO reports 2019 Nov 5;20(11):e47650
Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury.
Mo D, Tian W, Zhang HN, Feng YD, Sun Y, Quan W, Hao XW, Wang XY, Liu XX, Li C, Cao W, Liu WJ, Li XQ
European journal of pharmacology 2019 Nov 15;863:172701
European journal of pharmacology 2019 Nov 15;863:172701
Astaxanthin inhibits proliferation and induces apoptosis of LX‑2 cells by regulating the miR‑29b/Bcl‑2 pathway.
Zhu S, Wang T, Luo F, Li H, Jia Q, He T, Wu H, Zou T
Molecular medicine reports 2019 May;19(5):3537-3547
Molecular medicine reports 2019 May;19(5):3537-3547
Sirt2 epigenetically down-regulates PDGFRα expression and promotes CG4 cell differentiation.
Fang N, Cheng J, Zhang C, Chen K, Zhang C, Hu Z, Bi R, Furber KL, Thangaraj M, Nazarali AJ, Ji S
Cell cycle (Georgetown, Tex.) 2019 May;18(10):1095-1109
Cell cycle (Georgetown, Tex.) 2019 May;18(10):1095-1109
Fuplatin: An Efficient and Low-Toxic Dual-Prodrug.
Zhang R, Song XQ, Liu RP, Ma ZY, Xu JY
Journal of medicinal chemistry 2019 May 9;62(9):4543-4554
Journal of medicinal chemistry 2019 May 9;62(9):4543-4554
Casp8 hypomethylation and neural tube defects in association with polycyclic aromatic hydrocarbon exposure.
Huang Y, Ren A, Wang L, Jin L, Lin S, Li Z, McDonald JA
Clinical epigenetics 2019 May 7;11(1):72
Clinical epigenetics 2019 May 7;11(1):72
The protective effects of XH-105 against radiation-induced intestinal injury.
Cheng Y, Dong Y, Hou Q, Wu J, Zhang W, Tian H, Li D
Journal of cellular and molecular medicine 2019 Mar;23(3):2238-2247
Journal of cellular and molecular medicine 2019 Mar;23(3):2238-2247
Leonurine promotes neurite outgrowth and neurotrophic activity by modulating the GR/SGK1 signaling pathway in cultured PC12 cells.
Meng P, Zhu Q, Yang H, Liu D, Lin X, Liu J, Fan J, Liu X, Su W, Liu L, Wang Y, Cai X
Neuroreport 2019 Mar 6;30(4):247-254
Neuroreport 2019 Mar 6;30(4):247-254
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Shah SZA, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, Mangi MH, Wu W, Lai M, Zhang X, Duan Y, Wang L, Zhou X, Yang L
International journal of molecular sciences 2019 Mar 6;20(5)
International journal of molecular sciences 2019 Mar 6;20(5)
Long noncoding RNA CCAT2 promotes hepatocellular carcinoma proliferation and metastasis through up-regulation of NDRG1.
Liu Y, Wang D, Li Y, Yan S, Dang H, Yue H, Ling J, Chen F, Zhao Y, Gou L, Tang P, Huang A, Tang H
Experimental cell research 2019 Jun 1;379(1):19-29
Experimental cell research 2019 Jun 1;379(1):19-29
Protective effect of hyperoside against renal ischemia-reperfusion injury via modulating mitochondrial fission, oxidative stress, and apoptosis.
Wu L, Li Q, Liu S, An X, Huang Z, Zhang B, Yuan Y, Xing C
Free radical research 2019 Jul;53(7):727-736
Free radical research 2019 Jul;53(7):727-736
Role of Nkx2.5 in H(2)O(2)-induced Nsd1 suppression.
Liang X, Chu G, Wang L, Lai G, Zhao Y
Cell stress & chaperones 2019 Jul;24(4):697-707
Cell stress & chaperones 2019 Jul;24(4):697-707
Long-term pulmonary exposure to multi-walled carbon nanotubes promotes breast cancer metastatic cascades.
Lu X, Zhu Y, Bai R, Wu Z, Qian W, Yang L, Cai R, Yan H, Li T, Pandey V, Liu Y, Lobie PE, Chen C, Zhu T
Nature nanotechnology 2019 Jul;14(7):719-727
Nature nanotechnology 2019 Jul;14(7):719-727
Aloperine suppresses human pulmonary vascular smooth muscle cell proliferation via inhibiting inflammatory response.
Chang Z, Zhang P, Zhang M, Jun F, Hu Z, Yang J, Wu Y, Zhou R
The Chinese journal of physiology 2019 Jul-Aug;62(4):157-165
The Chinese journal of physiology 2019 Jul-Aug;62(4):157-165
PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol Efflux.
Zhou Y, Miles JR, Tavori H, Lin M, Khoshbouei H, Borchelt DR, Bazick H, Landreth GE, Lee S, Fazio S, Notterpek L
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Jul 3;39(27):5404-5418
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Jul 3;39(27):5404-5418
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Yang Y, Chen S, Tao L, Gan S, Luo H, Xu Y, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388
Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats.
Ying X, Tu W, Li S, Wu Q, Chen X, Zhou Y, Hu J, Yang G, Jiang S
Life sciences 2019 Jul 15;229:187-199
Life sciences 2019 Jul 15;229:187-199
YAP mediates the positive regulation of hnRNPK on the lung adenocarcinoma H1299 cell growth.
Xu L, Zhang T, Huang W, Liu X, Lu J, Gao X, Zhang YF, Liu L
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):677-687
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):677-687
Involvement of the microglial NLRP3 inflammasome in the anti-inflammatory effect of the antidepressant clomipramine.
Gong W, Zhang S, Zong Y, Halim M, Ren Z, Wang Y, Ma Y, Li B, Ma L, Zhou G, Yu J, Zhang J, Liu Q
Journal of affective disorders 2019 Jul 1;254:15-25
Journal of affective disorders 2019 Jul 1;254:15-25
Resveratrol protects against isoproterenol induced myocardial infarction in rats through VEGF-B/AMPK/eNOS/NO signalling pathway.
Feng L, Ren J, Li Y, Yang G, Kang L, Zhang S, Ma C, Li J, Liu J, Yang L, Qi Z
Free radical research 2019 Jan;53(1):82-93
Free radical research 2019 Jan;53(1):82-93
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA(2) phosphorylation.
Cao C, Dai L, Mu J, Wang X, Hong Y, Zhu C, Jin L, Li S
Cellular signalling 2019 Jan;53:151-161
Cellular signalling 2019 Jan;53:151-161
Matrix Metalloproteases-Mediated Cleavage on β-Dystroglycan May Play a Key Role in the Blood-Brain Barrier After Intracerebral Hemorrhage in Rats.
Zhang X, Gu Y, Li P, Jiang A, Sheng X, Jin X, Shi Y, Li G
Medical science monitor : international medical journal of experimental and clinical research 2019 Jan 28;25:794-800
Medical science monitor : international medical journal of experimental and clinical research 2019 Jan 28;25:794-800
Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells.
Shi H, Wang XL, Quan HF, Yan L, Pei XY, Wang R, Peng XD
Molecules (Basel, Switzerland) 2019 Jan 21;24(2)
Molecules (Basel, Switzerland) 2019 Jan 21;24(2)
KIAA1199 promotes metastasis of colorectal cancer cells via microtubule destabilization regulated by a PP2A/stathmin pathway.
Zhao L, Zhang D, Shen Q, Jin M, Lin Z, Ma H, Huang S, Zhou P, Wu G, Zhang T
Oncogene 2019 Feb;38(7):935-949
Oncogene 2019 Feb;38(7):935-949
Echinacoside protects against MPTP/MPP(+)-induced neurotoxicity via regulating autophagy pathway mediated by Sirt1.
Chen C, Xia B, Tang L, Wu W, Tang J, Liang Y, Yang H, Zhang Z, Lu Y, Chen G, Yang Y, Zhao Y
Metabolic brain disease 2019 Feb;34(1):203-212
Metabolic brain disease 2019 Feb;34(1):203-212
Activation of brain endothelium by Escherichia coli K1 virulence factor cglD promotes polymorphonuclear leukocyte transendothelial migration.
Zhang K, Shi MJ, Niu Z, Chen X, Wei JY, Miao ZW, Zhao WD, Chen YH
Medical microbiology and immunology 2019 Feb;208(1):59-68
Medical microbiology and immunology 2019 Feb;208(1):59-68
Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates.
Chen Z, Wang C, Li TF, Li K, Yue Y, Liu X, Xu HZ, Wen Y, Zhang Q, Han M, Komatsu N, Xu YH, Zhao L, Chen X
Nanomedicine (London, England) 2019 Feb;14(3):335-351
Nanomedicine (London, England) 2019 Feb;14(3):335-351
Structural and functional damage to the hippocampal neurovascular unit in diabetes-related depression.
Liu J, Wang YH, Li W, Liu L, Yang H, Meng P, Han YS
Neural regeneration research 2019 Feb;14(2):289-297
Neural regeneration research 2019 Feb;14(2):289-297
Exosomes from human adipose-derived stem cells promote sciatic nerve regeneration via optimizing Schwann cell function.
Chen J, Ren S, Duscher D, Kang Y, Liu Y, Wang C, Yuan M, Guo G, Xiong H, Zhan P, Wang Y, Machens HG, Chen Z
Journal of cellular physiology 2019 Dec;234(12):23097-23110
Journal of cellular physiology 2019 Dec;234(12):23097-23110
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Jiang YP, Yang JM, Ye RJ, Liu N, Zhang WJ, Ma L, Zheng P, Niu JG, Liu P, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Water-separated part of Chloranthus serratus alleviates lipopolysaccharide- induced RAW264.7 cell injury mainly by regulating the MAPK and Nrf2/HO-1 inflammatory pathways.
Sun S, Du Y, Yin C, Suo X, Wang R, Xia R, Zhang X
BMC complementary and alternative medicine 2019 Dec 2;19(1):343
BMC complementary and alternative medicine 2019 Dec 2;19(1):343
Hypoxic postconditioning activates the Wnt/β-catenin pathway and protects against transient global cerebral ischemia through Dkk1 Inhibition and GSK-3β inactivation.
Zhan L, Liu D, Wen H, Hu J, Pang T, Sun W, Xu E
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9291-9307
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9291-9307
Inhibition of dendritic spine extension through acrolein conjugation with α-, β-tubulin proteins.
Uemura T, Suzuki T, Ko K, Watanabe K, Dohmae N, Sakamoto A, Terui Y, Toida T, Kashiwagi K, Igarashi K
The international journal of biochemistry & cell biology 2019 Aug;113:58-66
The international journal of biochemistry & cell biology 2019 Aug;113:58-66
Overexpression of ANLN in lung adenocarcinoma is associated with metastasis.
Xu J, Zheng H, Yuan S, Zhou B, Zhao W, Pan Y, Qi D
Thoracic cancer 2019 Aug;10(8):1702-1709
Thoracic cancer 2019 Aug;10(8):1702-1709
Crocin induces anti-ischemia in middle cerebral artery occlusion rats and inhibits autophagy by regulating the mammalian target of rapamycin.
Huang Z, Xu J, Huang X, Sun G, Jiang R, Wu H, Shan X, Bao K, Wu Q, Wu H, Tao W
European journal of pharmacology 2019 Aug 15;857:172424
European journal of pharmacology 2019 Aug 15;857:172424
RMI1 contributes to DNA repair and to the tolerance to camptothecin.
Fang L, Sun X, Wang Y, Du L, Ji K, Wang J, He N, Liu Y, Wang Q, Zhai H, Hao J, Xu C, Liu Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Apr;33(4):5561-5570
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Apr;33(4):5561-5570
EIF4A2 interacts with the membrane protein of transmissible gastroenteritis coronavirus and plays a role in virus replication.
Song Z, Yang Y, Wang L, Wang K, Ran L, Xie Y, Huang L, Yang Z, Yuan P, Yu Q
Research in veterinary science 2019 Apr;123:39-46
Research in veterinary science 2019 Apr;123:39-46
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
Qin Z, Xiang C, Zhong F, Liu Y, Dong Q, Li K, Shi W, Ding C, Qin L, He F
Journal of experimental & clinical cancer research : CR 2019 Apr 11;38(1):154
Journal of experimental & clinical cancer research : CR 2019 Apr 11;38(1):154
NKX2-2 Suppresses Osteosarcoma Metastasis and Proliferation by Downregulating Multiple Target Genes.
Chen H, Liu W, Zhong L, Liao D, Zhang R, Kang T, Wu Y
Journal of Cancer 2018;9(17):3067-3077
Journal of Cancer 2018;9(17):3067-3077
Caffeine Promotes Conversion of Palmitic Acid to Palmitoleic Acid by Inducing Expression of fat-5 in Caenorhabditis elegans and scd1 in Mice.
Du X, Huang Q, Guan Y, Lv M, He X, Fang C, Wang X, Sheng J
Frontiers in pharmacology 2018;9:321
Frontiers in pharmacology 2018;9:321
EGFR as a Negative Regulatory Protein Adjusts the Activity and Mobility of NHE3 in the Cell Membrane of IPEC-J2 Cells With TGEV Infection.
Yang Z, Ran L, Yuan P, Yang Y, Wang K, Xie L, Huang S, Liu J, Song Z
Frontiers in microbiology 2018;9:2734
Frontiers in microbiology 2018;9:2734
Involvement of NMDA-AKT-mTOR Signaling in Rapid Antidepressant-Like Activity of Chaihu-jia-Longgu-Muli-tang on Olfactory Bulbectomized Mice.
Wang X, Zou Z, Shen Q, Huang Z, Chen J, Tang J, Xue W, Tao W, Wu H, Wang D, Chen G
Frontiers in pharmacology 2018;9:1537
Frontiers in pharmacology 2018;9:1537
Effect of Black Tea Extract and Thearubigins on Osteoporosis in Rats and Osteoclast Formation in vitro.
Liang Q, Lv M, Zhang X, Hu J, Wu Y, Huang Y, Wang X, Sheng J
Frontiers in physiology 2018;9:1225
Frontiers in physiology 2018;9:1225
Phosphorylation of IRS4 by CK1γ2 promotes its degradation by CHIP through the ubiquitin/lysosome pathway.
Li X, Zhong L, Wang Z, Chen H, Liao D, Zhang R, Zhang H, Kang T
Theranostics 2018;8(13):3643-3653
Theranostics 2018;8(13):3643-3653
Effect of decabrominated diphenyl ether exposure on spatial learning and memory, the expression and phosphorylation of hippocampal glutamate receptor subunits in adult Sprague-Dawley rats.
Xiong L, Liyue H, Fancai Z, Maoting L, Ya L, Ting H, Zhen Y, Shanshan Z, Wenwen G, Yan T
The Journal of toxicological sciences 2018;43(11):645-657
The Journal of toxicological sciences 2018;43(11):645-657
iTRAQ-Based Proteomics Analysis Reveals the Effect of Rhubarb in Rats with Ischemic Stroke.
Lin X, Liu T, Li P, He Z, Zhong Y, Cui H, Luo J, Wang Y, Tang T
BioMed research international 2018;2018:6920213
BioMed research international 2018;2018:6920213
The Protective Effect of New Compound XH-103 on Radiation-Induced GI Syndrome.
Dong Y, Cheng Y, Hou Q, Wu J, Li D, Tian H
Oxidative medicine and cellular longevity 2018;2018:3920147
Oxidative medicine and cellular longevity 2018;2018:3920147
PAX2 may induce ADAM10 expression in renal tubular epithelial cells and contribute to epithelial-to-mesenchymal transition.
Hou L, Du Y, Zhao C, Wu Y
International urology and nephrology 2018 Sep;50(9):1729-1741
International urology and nephrology 2018 Sep;50(9):1729-1741
Rapid induction of apoptosis in tumor cells treated with a new platinum(II) complex based on amino-thiazolidinone.
Song XQ, Liu YH, Shao J, Zhang ZL, Xie CZ, Qiao X, Bao WG, Xu JY
European journal of medicinal chemistry 2018 Sep 5;157:188-197
European journal of medicinal chemistry 2018 Sep 5;157:188-197
Theabrownin suppresses in vitro osteoclastogenesis and prevents bone loss in ovariectomized rats.
Liu T, Xiang Z, Chen F, Yin D, Huang Y, Xu J, Hu L, Xu H, Wang X, Sheng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1339-1347
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1339-1347
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Wang C, Luo H, Xu Y, Tao L, Chang C, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
Apolipoprotein E deficiency accelerates atherosclerosis development in miniature pigs.
Fang B, Ren X, Wang Y, Li Z, Zhao L, Zhang M, Li C, Zhang Z, Chen L, Li X, Liu J, Xiong Q, Zhang L, Jin Y, Liu X, Li L, Wei H, Yang H, Li R, Dai Y
Disease models & mechanisms 2018 Oct 10;11(10)
Disease models & mechanisms 2018 Oct 10;11(10)
hnRNPK modulates selective quality-control autophagy by downregulating the expression of HDAC6 in 293 cells.
Li Z, Liu X, Ma J, Zhang T, Gao X, Liu L
International journal of oncology 2018 Nov;53(5):2200-2212
International journal of oncology 2018 Nov;53(5):2200-2212
Temporal Proteomic Analysis of Pancreatic β-Cells in Response to Lipotoxicity and Glucolipotoxicity.
Li Z, Liu H, Niu Z, Zhong W, Xue M, Wang J, Yang F, Zhou Y, Zhou Y, Xu T, Hou J
Molecular & cellular proteomics : MCP 2018 Nov;17(11):2119-2131
Molecular & cellular proteomics : MCP 2018 Nov;17(11):2119-2131
Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells.
Tian T, Sun J, Wang J, Liu Y, Liu H
Oncology letters 2018 Nov;16(5):6133-6139
Oncology letters 2018 Nov;16(5):6133-6139
Horizontal transfer of exosomal CXCR4 promotes murine hepatocarcinoma cell migration, invasion and lymphangiogenesis.
Li M, Lu Y, Xu Y, Wang J, Zhang C, Du Y, Wang L, Li L, Wang B, Shen J, Tang J, Song B
Gene 2018 Nov 15;676:101-109
Gene 2018 Nov 15;676:101-109
KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.
Zhu ZC, Liu JW, Li K, Zheng J, Xiong ZQ
Oncogene 2018 May;37(22):2936-2952
Oncogene 2018 May;37(22):2936-2952
The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43.
Sun J, Hu Q, Peng H, Peng C, Zhou L, Lu J, Huang C
The Journal of biological chemistry 2018 May 25;293(21):8275-8284
The Journal of biological chemistry 2018 May 25;293(21):8275-8284
PMN inhibits colorectal cancer cells through inducing mitotic arrest and p53-dependent apoptosis via the inhibition of tubulin polymerization.
Wu X, Shen Y
Biochemical and biophysical research communications 2018 May 23;499(4):927-933
Biochemical and biophysical research communications 2018 May 23;499(4):927-933
Met is involved in TIGAR-regulated metastasis of non-small-cell lung cancer.
Shen M, Zhao X, Zhao L, Shi L, An S, Huang G, Liu J
Molecular cancer 2018 May 12;17(1):88
Molecular cancer 2018 May 12;17(1):88
Combined treatment with Dendrobium candidum and black tea extract promotes osteoprotective activity in ovariectomized estrogen deficient rats and osteoclast formation.
Wang MY, Shen C, An MF, Xie CQ, Wu X, Zhu QQ, Sun B, Huang YP, Zhao YL, Wang XJ, Sheng J
Life sciences 2018 May 1;200:31-41
Life sciences 2018 May 1;200:31-41
CCAAT/enhancer-binding protein β overexpression alleviates myocardial remodelling by regulating angiotensin-converting enzyme-2 expression in diabetes.
Tie Y, Zhai C, Zhang Y, Qin X, Yu F, Li H, Shan M, Zhang C
Journal of cellular and molecular medicine 2018 Mar;22(3):1475-1488
Journal of cellular and molecular medicine 2018 Mar;22(3):1475-1488
[USP33 suppresses lung adenocarcinoma lung cell invasion and metastasis by down-regulating SLIT2/ROBO1 signaling pathway].
Wang Y, Zhang S, Mu S, Zhang B, Ma S
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2018 Jul 30;38(8):956-961
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2018 Jul 30;38(8):956-961
PTEN-L promotes type I interferon responses and antiviral immunity.
Cao Y, Wang H, Yang L, Zhang Z, Li C, Yuan X, Bu L, Chen L, Chen Y, Li CM, Guo D
Cellular & molecular immunology 2018 Jan;15(1):48-57
Cellular & molecular immunology 2018 Jan;15(1):48-57
Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex.
Li Y, Wang L, Zhang X, Huang M, Li S, Wang X, Chen L, Jiang B, Yang Y
Neuropharmacology 2018 Jan;128:207-220
Neuropharmacology 2018 Jan;128:207-220
Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production.
Huang Y, Hua M, Cui X
Inflammation 2018 Feb;41(1):164-173
Inflammation 2018 Feb;41(1):164-173
Synergistic neuroprotective effect of rasagiline and idebenone against retinal ischemia-reperfusion injury via the Lin28-let-7-Dicer pathway.
Lei D, Shao Z, Zhou X, Yuan H
Oncotarget 2018 Feb 23;9(15):12137-12153
Oncotarget 2018 Feb 23;9(15):12137-12153
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
Wang B, Zhang G, Yang M, Liu N, Li YX, Ma H, Ma L, Sun T, Tan H, Yu J
Neurochemical research 2018 Dec;43(12):2404-2422
Neurochemical research 2018 Dec;43(12):2404-2422
The antidepressant effects of ɑ-tocopherol are related to activation of autophagy via the AMPK/mTOR pathway.
Huang X, Wu H, Jiang R, Sun G, Shen J, Ma M, Ma C, Zhang S, Huang Z, Wu Q, Chen G, Tao W
European journal of pharmacology 2018 Aug 15;833:1-7
European journal of pharmacology 2018 Aug 15;833:1-7
Pu-erh Tea Extract Ameliorates Ovariectomy-Induced Osteoporosis in Rats and Suppresses Osteoclastogenesis In Vitro.
Liu T, Ding S, Yin D, Cuan X, Xie C, Xu H, Wang X, Sheng J
Frontiers in pharmacology 2017;8:324
Frontiers in pharmacology 2017;8:324
Role of the Ubiquitin C-Terminal Hydrolase L1-Modulated Ubiquitin Proteasome System in Auditory Cortex Senescence.
Zhang Y, Huang X, Zhao XY, Hu YJ, Sun HY, Kong WJ
ORL; journal for oto-rhino-laryngology and its related specialties 2017;79(3):153-163
ORL; journal for oto-rhino-laryngology and its related specialties 2017;79(3):153-163
Neural Plasticity Associated with Hippocampal PKA-CREB and NMDA Signaling Is Involved in the Antidepressant Effect of Repeated Low Dose of Yueju Pill on Chronic Mouse Model of Learned Helplessness.
Zou Z, Chen Y, Shen Q, Guo X, Zhang Y, Chen G
Neural plasticity 2017;2017:9160515
Neural plasticity 2017;2017:9160515
Tail Nerve Electrical Stimulation and Electro-Acupuncture Can Protect Spinal Motor Neurons and Alleviate Muscle Atrophy after Spinal Cord Transection in Rats.
Zhang YT, Jin H, Wang JH, Wen LY, Yang Y, Ruan JW, Zhang SX, Ling EA, Ding Y, Zeng YS
Neural plasticity 2017;2017:7351238
Neural plasticity 2017;2017:7351238
Regulatory Axis of miR-195/497 and HMGA1-Id3 Governs Muscle Cell Proliferation and Differentiation.
Qiu H, Zhong J, Luo L, Tang Z, Liu N, Kang K, Li L, Gou D
International journal of biological sciences 2017;13(2):157-166
International journal of biological sciences 2017;13(2):157-166
2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G(2)/M cell cycle arrest through generation of thiol oxidative stress in human esophageal cancer cells.
Li X, Jiang Z, Feng J, Zhang X, Wu J, Chen W
Oncotarget 2017 Sep 22;8(37):61846-61860
Oncotarget 2017 Sep 22;8(37):61846-61860
Nrf2 Promotes Keratinocyte Proliferation in Psoriasis through Up-Regulation of Keratin 6, Keratin 16, and Keratin 17.
Yang L, Fan X, Cui T, Dang E, Wang G
The Journal of investigative dermatology 2017 Oct;137(10):2168-2176
The Journal of investigative dermatology 2017 Oct;137(10):2168-2176
Synthesis of β-tubulin occurs within chromatoid body of round spermatids.
Fujii Y, Fujita H, Yokota S
Cytoskeleton (Hoboken, N.J.) 2017 May;74(5):197-204
Cytoskeleton (Hoboken, N.J.) 2017 May;74(5):197-204
PRAS40 alleviates neurotoxic prion peptide-induced apoptosis via mTOR-AKT signaling.
Yang W, Yang LF, Song ZQ, Shah SZA, Cui YY, Li CS, Zhao HF, Gao HL, Zhou XM, Zhao DM
CNS neuroscience & therapeutics 2017 May;23(5):416-427
CNS neuroscience & therapeutics 2017 May;23(5):416-427
High expression of ubiquitin-specific peptidase 39 is associated with the development of vascular remodeling.
He S, Zhong W, Yin L, Wang Y, Qiu Z, Song G
Molecular medicine reports 2017 May;15(5):2567-2573
Molecular medicine reports 2017 May;15(5):2567-2573
Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages.
Fang W, Bi D, Zheng R, Cai N, Xu H, Zhou R, Lu J, Wan M, Xu X
Scientific reports 2017 May 10;7(1):1663
Scientific reports 2017 May 10;7(1):1663
MicroRNA-17-92 Regulates the Transcription Factor E2F3b during Myogenesis In Vitro and In Vivo.
Tang Z, Liu N, Luo L, Kang K, Li L, Ni R, Qiu H, Gou D
International journal of molecular sciences 2017 Mar 31;18(4)
International journal of molecular sciences 2017 Mar 31;18(4)
CBX3 promotes colon cancer cell proliferation by CDK6 kinase-independent function during cell cycle.
Fan Y, Li H, Liang X, Xiang Z
Oncotarget 2017 Mar 21;8(12):19934-19946
Oncotarget 2017 Mar 21;8(12):19934-19946
cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases.
Wang L, Lai G, Chu G, Liang X, Zhao Y
Experimental cell research 2017 Jun 1;355(1):18-25
Experimental cell research 2017 Jun 1;355(1):18-25
ERK1/2-mediated Cytoplasmic Accumulation of hnRNPK Antagonizes TRAIL-induced Apoptosis through Upregulation of XIAP in H1299 Cells.
Huang WS, Xu FM, Zeng QZ, Liu XH, Gao XJ, Liu LX
Biomedical and environmental sciences : BES 2017 Jul;30(7):473-481
Biomedical and environmental sciences : BES 2017 Jul;30(7):473-481
Abl2 kinase phosphorylates Bi-organellar regulator MNRR1 in mitochondria, stimulating respiration.
Aras S, Arrabi H, Purandare N, Hüttemann M, Kamholz J, Züchner S, Grossman LI
Biochimica et biophysica acta. Molecular cell research 2017 Feb;1864(2):440-448
Biochimica et biophysica acta. Molecular cell research 2017 Feb;1864(2):440-448
20-Hydroxyeicosatetraenoic acid regulates the expression of Nedd4‑2 in kidney and liver through a neddylation modification pathway.
Zhao J, Zhang B, Lai G, Xu R, Chu G, Zhao Y
Molecular medicine reports 2017 Dec;16(6):9671-9677
Molecular medicine reports 2017 Dec;16(6):9671-9677
miR-34b Modulates Skeletal Muscle Cell Proliferation and Differentiation.
Tang Z, Qiu H, Luo L, Liu N, Zhong J, Kang K, Gou D
Journal of cellular biochemistry 2017 Dec;118(12):4285-4295
Journal of cellular biochemistry 2017 Dec;118(12):4285-4295
Alginate enhances Toll-like receptor 4-mediated phagocytosis by murine RAW264.7 macrophages.
Bi D, Zhou R, Cai N, Lai Q, Han Q, Peng Y, Jiang Z, Tang Z, Lu J, Bao W, Xu H, Xu X
International journal of biological macromolecules 2017 Dec;105(Pt 2):1446-1454
International journal of biological macromolecules 2017 Dec;105(Pt 2):1446-1454
Knockdown of RMI1 impairs DNA repair under DNA replication stress.
Xu C, Fang L, Kong Y, Xiao C, Yang M, Du LQ, Liu Q
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):158-164
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):158-164
Overexpression of DBC1, correlated with poor prognosis, is a potential therapeutic target for hepatocellular carcinoma.
Li C, Liao J, Wu S, Fan J, Peng Z, Wang Z
Biochemical and biophysical research communications 2017 Dec 16;494(3-4):511-517
Biochemical and biophysical research communications 2017 Dec 16;494(3-4):511-517
LL-37-induced human mast cell activation through G protein-coupled receptor MrgX2.
Yu Y, Zhang Y, Zhang Y, Lai Y, Chen W, Xiao Z, Zhang W, Jin M, Yu B
International immunopharmacology 2017 Aug;49:6-12
International immunopharmacology 2017 Aug;49:6-12
The mechanically activated p38/MMP-2 signaling pathway promotes bone marrow mesenchymal stem cell migration in rats.
Yang Z, Wu B, Jia S, Zhao Y, Hou R, Liu X, Wang X, Chen L, Yang X, Lei D, Wang L
Archives of oral biology 2017 Apr;76:55-60
Archives of oral biology 2017 Apr;76:55-60
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
Shah SZA, Zhao D, Taglialatela G, Khan SH, Hussain T, Dong H, Lai M, Zhou X, Yang L
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
The DEAD-Box RNA Helicase DDX3 Interacts with NF-κB Subunit p65 and Suppresses p65-Mediated Transcription.
Xiang N, He M, Ishaq M, Gao Y, Song F, Guo L, Ma L, Sun G, Liu D, Guo D, Chen Y
PloS one 2016;11(10):e0164471
PloS one 2016;11(10):e0164471
Six2 Is a Coordinator of LiCl-Induced Cell Proliferation and Apoptosis.
Liu J, Ju P, Zhou Y, Zhao Y, Xie Y, Long Y, Gu Y, Ni D, Lyv Z, Mao Z, Hao J, Li Y, Wan Q, Kanyomse Q, Liu Y, Xiang Y, Wang R, Chen X, Zhang J, Liu X, Zhao H, Zhou Q, Li G
International journal of molecular sciences 2016 Sep 8;17(9)
International journal of molecular sciences 2016 Sep 8;17(9)
MicroRNA-378 Alleviates Cerebral Ischemic Injury by Negatively Regulating Apoptosis Executioner Caspase-3.
Zhang N, Zhong J, Han S, Li Y, Yin Y, Li J
International journal of molecular sciences 2016 Sep 2;17(9)
International journal of molecular sciences 2016 Sep 2;17(9)
Up-regulation of miR-95-3p in hepatocellular carcinoma promotes tumorigenesis by targeting p21 expression.
Ye J, Yao Y, Song Q, Li S, Hu Z, Yu Y, Hu C, Da X, Li H, Chen Q, Wang QK
Scientific reports 2016 Oct 4;6:34034
Scientific reports 2016 Oct 4;6:34034
Senkyunolide I attenuates oxygen-glucose deprivation/reoxygenation-induced inflammation in microglial cells.
Hu YY, Wang Y, Liang S, Yu XL, Zhang L, Feng LY, Feng Y
Brain research 2016 Oct 15;1649(Pt A):123-131
Brain research 2016 Oct 15;1649(Pt A):123-131
Conventional protein kinase Cβ-mediated phosphorylation inhibits collapsin response-mediated protein 2 proteolysis and alleviates ischemic injury in cultured cortical neurons and ischemic stroke-induced mice.
Yang X, Zhang X, Li Y, Han S, Howells DW, Li S, Li J
Journal of neurochemistry 2016 May;137(3):446-59
Journal of neurochemistry 2016 May;137(3):446-59
The tumor suppressor PTEN has a critical role in antiviral innate immunity.
Li S, Zhu M, Pan R, Fang T, Cao YY, Chen S, Zhao X, Lei CQ, Guo L, Chen Y, Li CM, Jokitalo E, Yin Y, Shu HB, Guo D
Nature immunology 2016 Mar;17(3):241-9
Nature immunology 2016 Mar;17(3):241-9
Hen egg white ovomacroglobulin promotes fibroblast migration via mediating cell adhesion and cytoskeleton.
Geng F, Huang X, Ma M
Journal of the science of food and agriculture 2016 Jul;96(9):3188-94
Journal of the science of food and agriculture 2016 Jul;96(9):3188-94
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
Tao X, Sun X, Xu L, Yin L, Han X, Qi Y, Xu Y, Zhao Y, Wang C, Peng J
Nutrients 2016 Jul 8;8(7)
Nutrients 2016 Jul 8;8(7)
Tubb3 regulation by the Erk and Akt signaling pathways: a mechanism involved in the effect of arginine ADP-ribosyltransferase 1 (Art1) on apoptosis of colon carcinoma CT26 cells.
Xiao M, Tang Y, Chen WW, Wang YL, Yang L, Li X, Song GL, Kuang J
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Feb;37(2):2353-63
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Feb;37(2):2353-63
Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers.
Wilcox KC, Marunde MR, Das A, Velasco PT, Kuhns BD, Marty MT, Jiang H, Luan CH, Sligar SG, Klein WL
PloS one 2015;10(4):e0125263
PloS one 2015;10(4):e0125263
Inhibition of autophagy by 3-MA enhances IL-24-induced apoptosis in human oral squamous cell carcinoma cells.
Li J, Yang D, Wang W, Piao S, Zhou J, Saiyin W, Zheng C, Sun H, Li Y
Journal of experimental & clinical cancer research : CR 2015 Sep 11;34(1):97
Journal of experimental & clinical cancer research : CR 2015 Sep 11;34(1):97
Expression of Iodotyrosine Deiodinase in Thyroid and Other Organs in Iodine-Deficient and Iodine-Excess Rats.
Sun X, Zhang X, Jiang Y, Bao S, Shan Z, Teng W
Biological trace element research 2015 Oct;167(2):272-9
Biological trace element research 2015 Oct;167(2):272-9
Regulation of signal transducer and activator of transcription 3 and apoptotic pathways by betaine attenuates isoproterenol-induced acute myocardial injury in rats.
Zheng P, Liu J, Mai S, Yuan Y, Wang Y, Dai G
Human & experimental toxicology 2015 May;34(5):538-47
Human & experimental toxicology 2015 May;34(5):538-47
SCD1 negatively regulates autophagy-induced cell death in human hepatocellular carcinoma through inactivation of the AMPK signaling pathway.
Huang GM, Jiang QH, Cai C, Qu M, Shen W
Cancer letters 2015 Mar 28;358(2):180-190
Cancer letters 2015 Mar 28;358(2):180-190
Expression and localization of estrogen receptor in human breast cancer and its clinical significance.
Li L, Wang Q, Lv X, Sha L, Qin H, Wang L, Li L
Cell biochemistry and biophysics 2015 Jan;71(1):63-8
Cell biochemistry and biophysics 2015 Jan;71(1):63-8
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo.
Xiao W, Jiang Y, Men Q, Yuan L, Huang Z, Liu T, Li W, Liu X
International journal of oncology 2015 Jan;46(1):360-8
International journal of oncology 2015 Jan;46(1):360-8
Quantitative proteomic study of myocardial mitochondria in urea transporter B knockout mice.
Du Y, Meng Y, Zhu J, Kang L, Jia X, Guo L, Zhang L, Ye M, Hu L, Zhao X, Gu J, Yang B, Zou H
Proteomics 2014 Sep;14(17-18):2072-83
Proteomics 2014 Sep;14(17-18):2072-83
The mechanisms of EGFR in the regulation of axon regeneration.
Xu MF, Zhou H, Hu CY, Liang YQ, Hu L, Chen D
Cell biochemistry and function 2014 Jan;32(1):101-5
Cell biochemistry and function 2014 Jan;32(1):101-5
CXXC5 Associates with Smads to Mediate TNF-α Induced Apoptosis.
Wang X, Liao P, Fan X, Wan Y, Wang Y, Li Y, Jiang Z, Ye X, Mo X, Ocorr K, Deng Y, Wu X, Yuan W
Current molecular medicine 2013 Sep;13(8):1385-96
Current molecular medicine 2013 Sep;13(8):1385-96
Downregulation of miR-181b in mouse brain following ischemic stroke induces neuroprotection against ischemic injury through targeting heat shock protein A5 and ubiquitin carboxyl-terminal hydrolase isozyme L1.
Peng Z, Li J, Li Y, Yang X, Feng S, Han S, Li J
Journal of neuroscience research 2013 Oct;91(10):1349-62
Journal of neuroscience research 2013 Oct;91(10):1349-62
Modulation of calcineurin activity in mouse brain by chronic oral administration of cyclosporine A.
Liu H, Tu L, Wang Q, Sun Y, Ma Y, Cen J, Wei Q, Luo J
IUBMB life 2013 May;65(5):445-53
IUBMB life 2013 May;65(5):445-53
Effect of pioglitazone on altered expression of Aβ metabolism-associated molecules in the brain of fructose-drinking rats, a rodent model of insulin resistance.
Luo D, Hou X, Hou L, Wang M, Xu S, Dong C, Liu X
European journal of pharmacology 2011 Aug 16;664(1-3):14-9
European journal of pharmacology 2011 Aug 16;664(1-3):14-9
Mutational analysis of ErbB2 intracellular localization.
Chen L, Qian L, Zhang Z, Shi M, Song Y, Yuan G, Zhang H, Hu M, Yu M, Zhang X, Shen B, Guo N
Histochemistry and cell biology 2007 Nov;128(5):473-83
Histochemistry and cell biology 2007 Nov;128(5):473-83
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10094-1-AP(tubulin-beta antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using 10094-1-AP and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-tubulin-beta (IP:10094-1-AP, 3ug; Detection:10094-1-AP 1:1000) with mouse brain tissue lysate 7500ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded rat brain using 10094-1-AP(tubulin-beta antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded rat brain using 10094-1-AP(tubulin-beta antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
