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- Antibody Data
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- References [1374]
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- Western blot [1]
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- Immunoprecipitation [1]
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- Product number
- 10094-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10094-1-AP, RRID:AB_2210695
- Product name
- beta Tubulin antibody
- Antibody type
- Polyclonal
- Description
- Beta Tubulin antibody (Cat. #10094-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
Submitted references Triptonide-mediated PTGS2 Inhibition Induces Autophagic Cell Death to Suppress the Progression of Triple-negative Breast Cancer and Epithelial Ovarian Cancer.
Chondroitin sulfate alleviates osteoarthritis by upregulating HSPA8 to inhibit chondrocyte ferroptosis.
Epithelial Gab1 Restricts Sepsis-Induced Intestinal Injury by Orchestrating TNF/NF-κB Axis.
Capg enhances proliferation, adipogenesis, and inflammatory response in preadipocytes: insights from bioinformatics analysis and functional validation.
NSMCE2 dispensability in mouse spermatogenesis suggests functional redundancy within the meiotic repair network.
RNF26 regulating tumor immunogenicity of hepatocellular carcinoma by degrading GRP78 and instigating ER stress.
RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability.
BCR::ABL1 tyrosine kinase inhibitors induce ribosome collisions to activate ZAK-dependent ribotoxic stress and apoptosis in chronic myeloid leukemia.
β-Sitosterol Suppresses Osteoclastogenesis and Alleviates Bone Loss by Targeting Tmed10 to Inhibit RANKL-Induced Hedgehog/MAPK Signaling and ROS.
Inhibitory effects of spermidine on lipopolysaccharide-induced inflammation in RAW 264.7 cells.
Small peptides derived from the autoinhibitory XY linker of phospholipase C-β isoforms inhibit enzyme activity and reduce inflammation.
Betrixaban activates cGAS and ERVs to promote dual nucleic-sensing antiviral immunity.
Huzhang-Xiangbaji compounds enhance the repair of meniscal cartilage by inhibiting ferroptosis and inflammatory microenvironment.
Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta-on-a-Chip Model.
AhR-Siglec-15 axis regulates lysosomal Ca2+ release for sonic hedgehog medulloblastoma growth via TRPML1.
Galangin 3-methyl ether alleviates mouse hypertrophic cardiomyopathy via targeting HDAC2 and subsequently inactivating the PI3K-AKT signaling pathway.
Lithospermic Acid Improves Doxorubicin-Induced Cardiomyopathy Through Sirtuin-3-Mediated Deacetylation of p53.
Baicalin Restores the Hypoglycemic Effect of Metformin by Regulating the Microbial Imidazole Propionate and Short-Chain Fatty Acids.
Cytosolic nucleic acid sensing triggers type I interferon activation via the Hippo kinase LATS1.
Decreased Glucose Metabolism and Declined Chaperones Are Unique Features Required for the Survival of Senescent Fibroblasts and Pyruvate Dehydrogenase Is a Potent Senolytic Target.
Reversibly unlocking the blood-brain barrier: A study on microtubule dynamics modulation using gold nanoparticle-modified reduced graphene oxide.
Royal jelly protein hydrolysates accelerate in vitro diabetic wound healing by enhancing keratinocytes functions and suppressing macrophage-mediated inflammation.
Targeting Apolipoprotein E4 rescues photoreceptor degeneration by inhibiting the disease-associated microglia activation in experimental retinal detachment.
STING Mediates Microglial Polarization to Promote Neuroinflammation in Epilepsy-Related Cognitive Dysfunction.
Dual targeting of PI3Kδ and PPARα enhances antitumor activity via FoxO1 activation in follicular lymphoma.
GEF-H1 upon microtubule destabilization drives ZBP1-dependent necroptosis.
B3GNT3 facilitates NFKB2 processing and non-canonical NF-κB activation to drive lung adenocarcinoma progression.
Synergistic Anti-Tumor Activity of LRPPRC Inhibition and Dasatinib Through Dual Oxidative Phosphorylation Disruption.
Tet methylcytosine dioxygenase 2(TET2)-dependent epigenetic regulation in the pathogenesis of polycystic ovary syndrome.
Amino acid supplementation enhances in vivo efficacy of lipid nanoparticle-mediated mRNA delivery in preclinical models.
Integrated fabrication of a shape-adaptable, antioxidative composite stent for effective closure and biological repair of enteroatmospheric fistula.
Geometry-driven immunomodulation in 3D-printed bioceramics: Negative curvature promotes macrophage M2 polarization via Ras-MAPK/HIF-1α signaling for vascularized osteogenesis.
Hepatic cavernous hemangioma decellularized extracellular matrix/GelMA composite hydrogel promotes angiogenesis via the ITGA9-FAK-ERK1/2 axis.
Extracellular vesicle-mediated transcellular mitophagy as a modulatory target for moderate hyperoxia-induced alveolar developmental arrest in bronchopulmonary dysplasia.
Polystyrene nanoplastics promote adipogenesis by stimulating nuclear translocation of PPARγ.
Design and synthesis of novel ATP-citrate lyase inhibitors and their effects on MAFLD/MASH.
Ailanthone ameliorates CCl(4)-induced liver fibrosis by targeting PKM2-mediated macrophage M1 polarization and glycolytic reprogramming.
Multi-omics analysis reveals Yishen Qutong formula promotes ferroptosis in Lewis lung cancer associated with Keap1/Nrf2/Nqo1 pathway modulation.
Shaoyao Gancao Decoction alleviates ulcerative colitis-associated secondary liver injury by inhibiting the phosphorylation of pyruvate dehydrogenase in macrophages.
HOMER3 drives oral squamous cell carcinoma progression through TRPV6 calcium influx and TUBB3 microtubule stabilization.
Neuroendocrine prostate cancer (NEPC)-associated CEP55 promotes cisplatin resistance in prostate cancer by regulating CDK1 phosphorylation.
Polydopamine nanoparticle-enhanced stem cell spheroid-derived decellularized extracellular matrix with antioxidant and tissue-adhesive properties for brain repair.
LncRNA FENDRR Inhibits Mitochondrial Apoptosis via TET2-Mediated DNA Demethylation of MFN1 in NSCPO.
METTL1-mediated m7G methylation of FoxO1 regulates lipid metabolism in metabolic dysfunction-associated fatty liver disease.
Nobiletin Ameliorates Skeletal Muscle Performance in D-Galactose-Induced Aging Mice by Boosting Aerobic Metabolism.
TNEA Regulates Hippocampal Oscillation by Improving Inhibitory Synaptic Plasticity to Ameliorates Cognitive Impairment in Alzheimer's Disease.
MXRA8, a key palmitoylation-related gene, promotes bladder cancer progression via remodeling tumor microenvironment and predicts poor prognosis.
HuangLong oral liquid alleviates cough variant asthma in mice via inhibiting M2 macrophage chemotaxis and polarization by regulating the PI3K/AKT/ERK pathway.
Neuroprotective effect of the herbal pair Coptidis Rhizoma-Cinnamomi Cortex against 6-OHDA-induced Parkinson's disease rats through promotion of autophagy via the PI3K/AKT/mTOR pathway.
Multi-Targeted Therapeutic Mechanisms of Huangqi Guizhi Wuwu Decoction Against Rheumatoid Arthritis: An Integrated Approach Combining Serum Pharmacochemistry, Network Pharmacology, Metabolomics, and Experimental Validation.
Vascular smooth muscle cell RNA-binding protein U2AF2 induces copper death by regulating C1qbp expression, delaying development of atherosclerosise.
In-situ RhoA editing via heparinylated LNP-microsphere system for rheumatoid arthritis treatment.
Danthron Attenuates Intestinal Inflammation by Modulating Oxidative Stress via the EGFR-PI3K-AKT and Nrf2-HO-1 Pathways.
Bone marrow-derived mesenchymal stem cells alleviate hepatic lipid metabolism disorders after scald injury: integrating liver transcriptome and metabolome.
Defining the Critical Role of α-Gustducin for NF-κB Inhibition and Anti-Inflammatory Signal Transduction by Bitter Agonists in Lung Epithelium.
BRD4-mediated transcriptional activation of PDLIM4 enhances p21 stability and chemosensitivity in lung adenocarcinoma independent of p53.
Size-dependent pyroptosis induction by calcium oxalate monohydrate crystals in HK-2 cells.
M1-like tumor-associated macrophages promote colorectal cancer progression through feedback activation of the IL1β/NF-κB signaling activity.
Time-of-Day Defines the Risk of Thermally Abused Frying Oil to Renal Injury by Modulating the Diurnal Dynamics of Oxylipins.
USP3 stabilizes MIC19 by deubiquitination under hypoxic stress and promotes the progression of non-small cell lung cancer.
TERT activator compound alleviates cigarette smoke-induced cognitive deficits by modulating hippocampal inflammation and neurogenesis: A comprehensive study integrating Mendelian randomization.
Intranasal delivery of Odorranalectin-modified lipid nanoparticles for multi-targeted therapy of Alzheimer's disease.
Genome-wide CRISPR screening identifies Annexin A1 as a facilitator of porcine astrovirus entry.
Exocarpium Citri Grandis-Derived Extracellular Vesicle-Like Particles for Accelerating Wound Healing via Regulating the Protein Expression on the VEGF/AKT Signaling Pathway.
HMMR is a novel prognostic marker and a potential therapeutic target for colon cancer.
VDLIN: A Deep Learning-Based Platform for Methylcobalamin-Inspired Immunomodulatory Compound Screening.
UBA5 deficiency disrupts mitochondrial autophagy via the PINK1-parkin pathway and impairs myoblast proliferation.
Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics.
Succinate Mediates Immune-Angiogenic Response by Activating Macrophage M2 Polarization in Oxygen-Induced Retinopathy.
Machine learning identifies a DNA repair-related risk model for bladder cancer and functionally characterizes ZWINT as a potential oncogenic factor.
Cepharanthine alleviated chronic prostatitis/chronic pelvic pain syndrome by activating Nrf2 and inhibiting the NF-κB pathway.
Deacetylation of BmHSP90 at Lysines 550/567 Stimulates Its Chaperone Function and Actin Polymerization to Drive the Proliferation of Bombyx mori Nucleopolyhedrovirus.
VAMP7-dependent late endosomal secretion of ER and mitochondrial proteins impacts the tumor microenvironment and macrophage engagement.
DUX4-induced HSATII RNA accumulation drives protein aggregation, impacting RNA processing pathways.
Taurine suppresses gastric intestinal metaplasia in patient-derived organoids and Atp4a (-/-) mice.
Y chromosome-linked EIF1AY deletion drives sex differences in multiple myeloma.
African swine fever virus DEAD-box helicase D1133L promotes OGG1-driven incision of genomic 8-oxoG via HDAC5 deacetylation.
The Bushen Huatan formula inhibits TP53-Mediated ferroptosis and modulating lipid metabolism in polycystic ovary syndrome abnormalities rat model.
Gut microbial ammonia as a mediator of PFOS neurotoxicity and its remediation by the flavonoid Icaritin.
ARID1B regulates sphingolipid metabolism and myelin development via STAG2: Mechanistic insights into ARID1B-related coffin-siris syndrome.
Yueju pill exerts long-lasting antidepressant effects through PACAP-mediated NG2 signaling and enhance hippocampal synaptic proteins.
The GOLM1-ACLY pathway regulates macrophage-secreted EFEMP1 via H3K27ac modifications to drive tumor progression.
Loss of TRAIP Could Attenuate the Breast Cancer Cells Development by Regulating PLSCR4 Stabilization.
Unlocking an Efficient SOD-to-CAT Catalytic Relay in a MOF Nanozyme via Dopamine-Driven Interfacial Nanoreconstruction for Osteoarthritis Therapy.
RUVBL2 Regulates Microglia Metabolic Reprogramming to Mediate Stress Granules Aggregation Exacerbating Postoperative Delirium in Aged Mild Cognitive Impairment Rats.
Neuronal phenotypic alterations and the therapeutic potential of Anxa2 in traumatic brain injury recovery.
Re-analysis of single-cell transcriptomics reveals a critical role of TNS1 gene in driving contractile VSMC transdifferentiation into macrophage-like SMC and atherosclerotic plaque instability.
Targeting SLC5A2 suppresses colorectal tumour development by enhancing NK cell activity through extracellular vesicle-dependent MICA/B signalling.
Celastrol disrupts the inflammatory feedback loop driven by Tenascin-C⁺ fibroblast subtype in psoriasis: Insights from single-cell RNA sequencing and experimental validation.
PSAT1 Promotes NSCLC Progression via the De Novo Serine Synthesis Pathway and Represents a Therapeutic Vulnerability.
Ascites circRNA ASCOR Drives Platinum Resistance of High-Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation.
CircPBX1 ameliorates metabolic memory-associated erectile dysfunction via miR-195-5p/YAP1-mediated angiogenesis in diabetic rats.
Evolutionarily conserved signaling intermediate in Toll pathways facilitates exercise-induced amelioration of skeletal muscle atrophy by maintaining mitochondrial quality control in middle-aged mice.
Cardiomyocytes FGFBP1 induction by STAT3 drives pathological cardiac remodeling.
CuET inhibits Ewing sarcoma of bone progression through modulation of the ESM1-MAPK/ERK signaling axis.
ADAM15 promotes the progression and metastasis of hepatocellular carcinoma by activating the JNK/p38 pathway.
GM-CSF exacerbates pulmonary arterial hypertension via CCL2/CCR2-axis-mediated macrophage NLRP3 inflammasome activation.
PRMT1-Mediated PARP1 Methylation Drives Lung Metastasis and Chemoresistance via P65 Activation in Triple-Negative Breast Cancer.
Eucommia ulmoides extract attenuates oxidative stress and promotes melanogenesis via Wnt/β-catenin signaling in B16 cells and mice.
Histone Methyltransferase EHMT2 Promotes the Progression of Breast Ductal Carcinoma by Regulating the Hippo Pathway.
A Mesoporous Silica-Based Naringenin Delivery System Promoting Macrophage M2 Polarization in Atherosclerosis.
Ginsenoside Rh2-Pretreated Mesenchymal Stem Cell Exosomes Ameliorate Collagen-Induced Arthritis via N6-Methyladenosine Methylation.
Inhibition of Mettl3 alleviates low-dose cisplatin-induced renal fibrosis and enhances the chemotherapeutic efficacy in mouse models of cancer.
Novel Duck Orthoreovirus σA Protein Inhibits Interferon Signaling by Impeding STAT1/STAT2 Nuclear Translocation.
Hsa_circ_0006834 represses intrahepatic cholangiocarcinoma proliferation through activating AMPK-mTOR pathway and autophagy via has-miR-637-NGFR network.
Accelerated peripheral nerve repair using surface-modified biomaterials for targeted capture of glial-derived growth factors post-neurorrhaphy.
Plasma-activated media inhibits epithelial-mesenchymal transition and ameliorates intestinal fibrosis through the PPARγ/TGF-β1/SMAD3 pathway.
Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation.
ROS-Responsive Nanosystem Targeted Co-Delivery YC-1 and Regorafenib to Alleviate Hypoxia Enhancing Hepatocellular Carcinoma Therapy.
Lymph Node Exosomes Delivery Attenuates Myocardial Ischemia-Reperfusion Injury via Regulating PTEN-PI3K/Akt Pathway Mediated Myocardiocyte Apoptosis.
Fibroblast Growth Factor 20 Attenuates Colitis by Restoring Impaired Intestinal Epithelial Barrier Integrity and Modulating Macrophage Polarization via S100A9 in an NF-κB-Dependent Manner.
Probiotic supplementation attenuated early-life chemotherapy-induced brain development impairment in mice.
NCAPG promotes the malignant progression of endometrioid cancer through LEF1/SEMA7A/PI3K-AKT.
Cryptococcus neoformans phospholipase B1 is critical for cryptococcoma formation in the mouse brain.
GDF15 is associated with thyroid cancer progression and may modulate thyroid cancer cell senescence in a p53-dependent manner.
c-Met inhibitor NVP-BVU972 induces antiviral protection and suppresses NF-κB-mediated inflammation.
To reveal biomarkers related to macrophage and lactic acid metabolism in renal fibrosis and explore their mechanisms.
Identification and evaluation of a pinocembrin analog as a TRPV1 inhibitor with analgesic properties in murine pain models.
Stimulation of regulatory dendritic cells suppresses cytotoxic T cell function and alleviates DEN-induced liver injury, fibrosis and hepatocellular carcinoma.
Phosphoglycerate kinase 1 as a potential prognostic biomarker in papillary thyroid carcinoma.
The integrated analysis of SIRT family expression, prognostic value, and potential implications in childhood acute lymphoblastic leukemia.
Hypoxia promotes pancreatic adenocarcinoma progression by stabilizing ID1 via TRIM21 suppression.
Betrixaban is a broad anti-virus inhibitor by activating innate immunity.
Comprehensive Insights Into the Role of TRPM4 in Pan-Cancer Progression and Immune Regulation.
Inhibitors of KAT2A Alleviate the Progression of AKI by Alleviating Macrophage Ferritinophagy.
Peroxisome proliferator-activated receptors-mediated diabetic wound healing regulates endothelial cells' mitochondrial function via sonic hedgehog signaling.
Spatiotemporal regulation of the bone immune microenvironment via a 'Zn(2+)-quercetin' hierarchical delivery system for bone regeneration.
Integrated Transcriptomic Analysis Leveraging Single-Cell and Bulk RNA Sequencing Data to Uncover Pyroptosis-Related Prognostic Signatures in HCC.
Tremella fuciformis Polysaccharides Alleviate Early Brain Injury in Experimental Subarachnoid Hemorrhage by Inhibiting the KDR-Mediated P38 MAPK/NF-κB Pathway.
Phytosphingosine Alleviates Cigarette Smoke-Induced Bronchial Epithelial Cell Senescence in Chronic Obstructive Pulmonary Disease by Targeting the Free Fatty Acid Receptor 4.
Single-protein/RNA imaging reveals ZNF598 as a limiting factor in resolving collided ribosomes.
Hepatic ASPG-mediated lysophosphatidylinositol catabolism impairs insulin signal transduction.
SARS-CoV-2 nucleocapsid protein delays cell cycle in S-phase.
Nuclear localization of platelet activating factor receptor accounts for microglial phagocytosis in ischemic stroke.
RHOD mediates ATG9A trafficking to promote autophagosome formation during autophagy in cancer.
Gut Microbiota Regulate Lipid Metabolism via the Bile Acid Pathway: Resistance to Hypoxia in Gansu Zokor (Eospalax cansus).
Choline reduces inflammatory response and lipid accumulation in calf hepatocytes induced by NEFA via inhibiting ROS/ NF-κB/NLRP3 inflammasome axis.
EcSnx27 facilitates in vitro release of Singapore grouper iridovirus and interacts with its major capsid protein.
DDIT4 knockdown suppresses venous malformation progression by inhibiting NF-κB signaling as a potential therapeutic target.
AARS1-mediated Osterix lactylation promotes its transcriptional activity during osteoblast differentiation.
Gut Metabolite Indole-3-Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging-Related Myocardial Fibrosis.
NFATc4 Promotes Lung Adenocarcinoma Progression via the CCNB1/CDK1 Pathway and Is a Potential Prognostic Biomarker.
Genome-wide CRISPR/Cas9 screen identifies host factors for Newcastle disease virus replication.
Enhancement of spinal cord injury repair in rats using photo-crosslinked GelMA hydrogel combined with mitochondrial transplantation.
Peroxisome Proliferator-Activated Receptor Gamma (PPARγ)-targeted Gel/Mg/Lip@Gigantol nanoplatform attenuates skin barrier disruption-associated aging in mice via NLRP3 suppression.
RfeA from Streptococcus suis serotype 2 triggers NLRP3/Caspase-1-dependent pyroptosis leading to blood-brain barrier disruption.
Jiao-Ai Decoction and active ingredients promoted angiogenesis to alleviate threatened abortion through miR-16 mediated VEGF/VEGFR signaling pathway.
Integration of network pharmacology and transcriptomics to reveal the mechanism of Paeoniae Radix Alba Polysaccharide in alleviating hepatic fibrosis.
Inhalation of Mesenchymal-Stem-Cell-Derived Nanovesicles Delivering Catalase Enhances the Treatment for Acute Lung Injury.
Lithospermic acid improves diabetic kidney fibrosis by regulating Piezo1/TGF-β1/Smad signaling pathway.
MSTRG.118323.5 targets BAG5 as a miR-200-y sponge to regulate Sertoli cells apoptosis via PI3K/AKT/mTOR pathways of Bactrian camels.
Reduced mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology.
Reduced growth and biofilm formation at high temperatures contribute to Cryptococcus deneoformans dermatotropism.
Influence of Sevoflurane Postconditioning on Hypoxic-Ischemic Brain Injury via Nrf2-Regulated Ferroptosis in Neonatal Rats.
TAP1 promotes immune escape by activating JNK/STAT1/PD-L1 signaling in EBV-associated gastric cancer.
OTUD1 downregulates PD-L1 expression by deubiquitinating STAT3 and promotes the immune response in ccRCC.
Tailoring the therapeutic potential of stem cell spheroid-derived decellularized ECM through post-decellularization BDNF incorporation to enhance brain repair.
MitoQ alleviates prion-induced neurodegeneration by modulating DRP1- and OPA1-mediated mitochondrial dynamics.
Endogenous synthesis of n-3 PUFAs can reduce lipid synthesis in Fad3 transgenic cattle.
Propofol-mediated inhibition of ovarian function by mitophagy over-activation via TGF-β1/SMAD2/3 signaling pathway.
Cancer Cell-Derived Large Extracellular Vesicles Promote Venous Thromboembolism by Activating NETosis Through Delivering CYBA.
Nanovesicles Synergistically Regulate Ferroptosis Characteristic Macrophage-Induced Angiogenesis via Ferritin Heavy Chain 1/Glutathione Peroxidase 4 Pathway to Promote Peripheral Nerve Regeneration.
Identification of human RNA Polymerase II interactors at early stages of transcription.
ANK3 Is Regulated by Recursive Splicing and Inhibits Hepatocellular Carcinoma Metastasis by Inhibiting E-Cadherin Protein Degradation.
Rosmarinic acid improves intestinal barrier integrity through PI3K/AKT/Nrf2-mediated regulation of tight junction protein expression.
The activation of hippocampus microglia in the occurrence of airway hyperresponsiveness comorbidity anxiety.
PADI2 exacerbates Mycoplasma ovipneumoniae-induced lung injury in sheep by suppressing M2 macrophage polarization.
Cephalomannine as in vitro and in vivo anticancer agent in mesothelioma cells: mechanisms of action.
Menaquinone-4 ameliorates abdominal aortic aneurysm by suppressing ferroptosis through NRF2/GCLM axis.
PTEN-L dephosphorylates Parkin and Ub Ser65 to aggravate mitophagy dysfunction in prion disease cell models.
Exosomal transfer of miR-375-3p from pancreatic β cells to hepatocytes impairs hepatic glycogenesis via Rbpj repression.
Panax notoginseng Flower Extract Attenuates Pentylenetetrazole-Induced Epilepsy by Restoring Glutamate Homeostasis.
Corilagin regulates antigen processing and presentation by directly binding to inhibit ERAP1.
Rab26-mediated lysosomal translocation of eEF1A alleviates myocardial hypertrophy and cardiac remodeling.
A BACH1 inhibitor ameliorates myocardial infarction and limb ischemia in mice.
Nuclearporin subcomplex Nup98/Rae1 is vital for maternal-to-zygotic transition during early embryonic development.
Mangiferin targets PFKFB3 to inhibit glioblastoma progression by suppressing glycolysis and PI3K/AKT/mTOR signaling.
MicroRNA-592 suppresses breast cancer progression by targeting CYP20A1 to modulate the CHOP pathway.
Molecular mechanism of the crosstalk between glucocorticoid receptor (GR) and hypoxia-inducible factor 3α (HIF-3α) pathways.
Activation of the C3 Complement Pathway in the Hippocampus Produces Anxiodepressive Effects in a Mouse Model of Inflammation Pain.
Fingolimod Exerts Therapeutic Effects on Autistic Mice via Improving the Structure and Function of Meningeal Lymphatics.
HAX1 mediates SARS-CoV-2 spike-triggered unfolded protein response in host cells.
Very high-dose vitamin D₃ supplementation reduces the expression of genes and proteins engaged in β-oxidation in healthy pigs.
Treadmill exercise alleviates STING-mediated microglia pyroptosis and polarization via activating mitophagy post-TBI.
Discovery of KMT5A repressed miR-99b cluster with potential to restore chemotherapy sensitivity in gastric cancer by regulating mitochondrial complex II and affecting OXPHOS.
Analysis of antiviral functions, differences and apoptotic effects of two novel MHC-Iα genotypes in orange-spotted grouper (Epinephelus coioides).
USP20 competitively binds to STUB1 to enhance CTSL expression and promote epithelial-mesenchymal transition in head and neck squamous cell carcinoma.
Brain endothelial HIF-1α exacerbates diabetes-associated cognitive impairment by accelerating glycolysis-driven lactate production.
Understanding the impact of glycolysis and oxidative stress on residual feed intake in slow-growing chicken.
circ_0000132 Regulates Chicken Granulosa Cell Proliferation Apoptosis and E2/P4 Synthesis via miR-206 E2F5 Signaling.
DDX1 facilitates lenvatinib resistance in hepatocellular carcinoma through regulating ephrin-A3 and activating the Wnt/β-catenin signaling pathway.
MYST1-Mediated Lysine Acetylation Stabilizes KLF4 to Promote Intimal Hyperplasia.
Elevating cytosolic NADPH metabolism in endothelial cells ameliorates vascular aging.
Regulatory role of sirtuin-1 by targeting MDM2 to mitochondria-associated membranes formation in the treatment of NAFLD.
Cisplatin-encapsulated zeolitic imidazolate framework-8 nanosystem enhanced radiosensitivity of non-small cell lung cancer.
Acetylbinankadsurin A Decreases Macrophage Glycolysis and Pro-Inflammatory Phenotype Polarization via Inhibiting HIF-1α to Alleviate Hepatic Fibrosis in Mice.
GDF11 alleviates glucocorticoid-induced osteonecrosis of the femoral head by regulating angiogenesis via the PI3K-AKT-eNOS pathway.
Tunneling nanotube-mediated stem cell immunomodulation dysfunction promotes adipose inflammation and insulin resistance in GDM.
Zhenqi Fuzheng Granule targets the SCFAs-GPR109A axis to enhance PD-1 antibody efficacy via immunometabolic remodeling in colorectal cancer.
MPP(+) disorders Irg1-Itaconate axis to promote M1 polarization of microglia by activating succinate dehydrogenase.
Design, Synthesis and Anticancer Activity of 6-Substituted-1-(3,4,5-trimethoxyphenyl)-1H-indole Against Tubulin Polymerisation.
PD-L1(+) neutrophils trigger pulmonary endothelial pyroptosis via an oxidative phosphorylation-dependent mechanism in sepsis.
Dynamic remodelling of epithelial plasticity in colorectal cancer from single-cell and spatially resolved perspectives.
Roseburia hominis enriched by baicalin reverses the non-response to metformin via upregulating linolenic acid metabolism.
Identification of novel biomarkers for hypertension and ventricular remodeling based on transcriptomics and machine learning.
N7-methylguanosine-related gene decapping scavenger enzymes as a novel biomarker regulating epithelial cell function in diabetic foot ulcers.
A novel angiotensin II type 2 receptor antagonist TDI05 alleviates the peripheral neuropathic pain.
Naringenin targets and inhibits Monoamine Oxidase A/B to bidirectionally regulate intestinal motility.
Bioinformatics and validation reveal spinal cord cathepsin S potential degradation of perineuronal nets in neuropathic pain.
Oxidative damage to lung mitochondrial DNA is a key contributor to the development of chemical lung injury.
Circulating Mitochondrial N-Formyl Peptides Are Associated with Acute Respiratory Distress Syndrome after Cardiopulmonary Bypass and Regulate Endothelial Barrier through FPR2.
Vitamins D and K jointly protect against osteoarthritis via regulating OSCAR during osteoclastogenesis.
Regulation of N-Glycosylation of CDNF on Its Protein Stability and Function in Hypoxia/Reoxygenation Model of H9C2 Cells.
Cyclic RGD modified dextran-quercetin polymer micelles for targeted therapy of breast cancer.
Histone acetyltransferase BmMOF inhibits the proliferation of the Bombyx mori nucleopolyhedrovirus by targeting Bmp53.
De Novo Protein Synthesis Occurs Through the Cytoplasmic Translation Machinery in Mammalian Spermatozoa.
Pad2 deletion induces anxiety‑like behaviors and memory deficits in mice.
Distinct In Vitro Differentiation Protocols Differentially Affect Cytotoxicity Induced by Heavy Metals in Human Neuroblastoma SH-SY5Y Cells.
Myd88 functions as a negative regulator of IRF11-mediated IFN production in teleosts.
Sauchinone preserves cardiac function in doxorubicin-induced cardiomyopathy by inhibiting the NLRP3 inflammasome.
Identification and Functional Analysis of Novel Mutations in AXIN2 and LRP6 Linked With Non-Syndromic Tooth Agenesis.
LMTK2 and CRB1 are two novel risk genes for Alzheimer's disease in Han Chinese.
MARVELD1 inhibits Neuro2a cell migration and tumorigenesis via regulating the transcriptional coactivators and protein methylation.
Inactivation of TACC2 epigenetically represses CDKN1A and confers sensitivity to CDK inhibitors.
A Novel Role of Adipokine 'Intelectin-1': Ameliorating Renal Fibrosis Through Inhibition of Renal Tubular Epithelial Cell Senescence.
Multi-parameter magnetic resonance imaging of zebularine in liver fibrosis treatment and calcineurin/NFAT3 mechanism.
Complement C4 exacerbates astrocyte-mediated neuroinflammation and promotes α-synuclein pathology in Parkinson's disease.
The Therapeutic Potential of Bombyx Batryticatus for Chronic Atrophic Gastritis Precancerous Lesions via the PI3K/AKT/mTOR Pathway Based on Network Pharmacology of Blood-Entering Components.
Targeting of the IL-33/Wnt axis restricts breast cancer stemness and metastasis.
TREM2 deficiency exacerbates cognitive impairment by aggravating α-Synuclein-induced lysosomal dysfunction in Parkinson's disease.
ZLN005, a PGC-1α agonist, delays photoreceptor degeneration by enhancing mitochondrial biogenesis in a murine model of retinitis pigmentosa.
PAI-1-driven SFRP2(high) cancer-associated fibroblasts hijack the abscopal effect of radioimmunotherapy.
HBV core protein enhances WDR46 stabilization to upregulate NUSAP1 and promote HCC progression.
Distinct Transcriptomic Profiles of Cultured Anterior and Posterior Populations of Human Infant Scleral Fibroblasts: Including Dopamine Receptors.
Inhibition of microRNA-139-5p by glucagon-like peptide-1 ameliorates oxidative stress-induced vascular endothelial cell damage via targeting SOD1/GCLc.
Computational and functional prioritization identifies genes that rescue behavior and reduce tau protein in fly and human cell models of Alzheimer disease.
Lentinan alleviates cadmium-induced kidney injury by reducing cadmium accumulation via promoting cadmium excretion and metallothionein synthesis and regulating silencing information regulator1/nuclear factor erythroid 2-related factor 2/nuclear factor kappa-B signaling pathway.
Mitochondrial-Derived Signaling Mediates Differentiation of Parietal Epithelial Cells into Podocytes.
Study on metabolic disorders in rat liver induced by different times after scalds.
Astragaloside IV Relieves Central Sensitization by Regulating Astrocytic ROS/NF-κB Nuclear Translocation Signaling in Chronic Migraine Male Rats.
GIMAP1 interacts with TMX1 to improve lung adenocarcinoma prognosis by influencing tumor immune microenvironment.
KEAP1-NRF2/HO-1 Pathway Promotes Ferroptosis and Neuronal Injury in Schizophrenia.
Allium Macrostemon Bge. Attenuates the Cognitive Decline of Aging Mice by Enhancing BDNF/TrkB Pathway.
ANXA2 promotes chondrocyte differentiation and fracture healing by regulating the phosphorylation of STAT3 and PI3K/AKT signaling pathways.
Semaglutide, a glucagon-like peptide-1 receptor agonist, inhibits oral squamous cell carcinoma growth through P38 MAPK signaling pathway.
Inhibiting HMGB1/AGER/NF-κB pathway prevents pro-inflammatory microglia polarization and protect photoreceptors in retinitis pigmentosa.
Lactate Dehydrogenase A Crotonylation and Mono-Ubiquitination Maintains Vascular Smooth Muscle Cell Growth and Migration and Promotes Neointima Hyperplasia.
Uric acid promotes aortic valve calcification via mediating valve interstitial cell osteogenic differentiation and endothelial dysfunction.
Arsenic enhances cervical cancer cell radiosensitivity by suppressing the DNA damage repair pathway.
Neurotransmitter 5-HT Further Promotes LL-37-Induced Rosacea-like Inflammation Through HTR3A.
Mitochondrial miRNA miR-134-5p Play Oncogenic Role in Clear Cell Renal Cell Carcinoma.
S1PR3 in hippocampal neurons improves synaptic plasticity and decreases depressive behavior via downregulation of RhoA/ROCK1.
IFI16 recruits HDAC1 and HDAC2 to deacetylate the Kaposi's sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen (LANA), facilitating latency.
Neuroprotective effect of apo-9'-fucoxanthinone against cerebral ischemia injury by targeting the PI3K/AKT/GSK-3β pathway.
Mitochondrial Calcium Uniporter knockdown improves the viability of HT22 hippocampal neurons in Alzheimer's disease.
Polo-like kinase2 regulates renal tubulointerstitial fibrosis via notch signaling pathway in diabetic kidney disease.
YTHDC1 negatively regulates UBE3A to influence RAD51 ubiquitination and inhibit apoptosis in colorectal cancer cells.
Design of Selective BRD4 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease.
Blueberry Anthocyanin Extracts (BAEs) Protect Retinal and Retinal Pigment Epithelium Function from High-Glucose-Induced Apoptosis by Activating GLP-1R/Akt Signaling.
Intrinsic differences in mTOR activity mediates lineage-specific responses to cyclophosphamide in mouse and human granulosa cells.
Prognostic implications and characterization of tumor-associated tertiary lymphoid structures genes in pancreatic cancer.
LINC02154 Promotes Esophageal Squamous Cell Carcinoma Progression via the PI3K-AKT-mTOR Signaling Pathway by Interacting With IGF2BP2.
H3K18 lactylation-mediated SIX1 upregulation contributes to silica-induced epithelial-mesenchymal transition in airway epithelial cells.
Crosstalk Between Th17 Cells and Renal Tubular Epithelial Cells Promotes Fibrotic Progression in IgA Nephropathy.
K(+)-H(+) coupling strategy for immune regulation and bone defect repair.
Cryo-trojan mesenchymal stem cells as non-living tumor-homing supercarriers for enhanced drug delivery and immune activation in prostate cancer.
Transcriptome profiling reveals that the host BRD4 protein facilitates African swine fever virus infection and suppresses inflammatory cytokine expression by downregulating transcriptional regulatory signaling pathways.
Melatonin attenuates inflammatory bone loss by alleviating mitophagy and lactate production.
HDAC9 Deficiency Upregulates cGMP-dependent Kinase II to Mitigate Neuronal Apoptosis in Ischemic Stroke.
An Energy Metabolism Nanoblocker for Cutting Tumor Cell Respiration and Inhibiting Mitochondrial Hijacking from Cytotoxic T Lymphocyte.
Vegfr3 activation of Pkd2l1(+) CSF-cNs triggers the neural stem cell response in spinal cord injury.
A Novel Theranostic Strategy for Malignant Pulmonary Nodules by Targeted CECAM6 with (89)Zr/(131)I-Labeled Tinurilimab.
Knockdown of RUNX2 Attenuated A1 Astrocyte Overactivation, Brain Injury, and Cerebral Edema During Ischemic Stroke.
VIRMA-mediated m(6)A modification regulates forebrain formation through modulating ribosome biogenesis.
Peptide Hydrogels for Renal Carcinoma Therapy via Synergistic Inhibition of Glycolysis and Mitochondrial Metabolism Reprogramming.
STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma.
Yinchenhao Decoction Mitigates Cholestatic Liver Injury in Mice via Gut Microbiota Regulation and Activation of FXR-FGF15 Pathway.
Excretory/secretory products from Hymenolepis nana adult worms alleviate ulcerative colitis in mice via tuft/IL-13 signaling pathway.
Pretreatment with Citrus reticulata 'Chachi' Polysaccharide Alleviates Alcohol-Induced Gastric Ulcer by Inhibiting NLRP3/ASC/Caspase-1 and Nrf2/HO-1 Signaling Pathways.
Long Non-Coding RNA LOC401312 Induces Radiosensitivity Through Upregulation of CPS1 in Non-Small Cell Lung Cancer.
Sleep deficiency exacerbates periodontal inflammation via trigeminal TRPV1 neurons.
The Effect of FPR2 on the Regulation of Trophoblast Autophagy via the PI3K/AKT/mTOR Signaling Pathway in Preeclampsia.
Direct Peritoneal Resuscitation and Melatonin in the Treatment of Abdominal Sepsis-Induced Lung Injury via Macrophage Metabolic Reprogramming.
Silencing YTHDF2 Induces Apoptosis of Neuroblastoma Cells In a Cell Line-Dependent Manner via Regulating the Expression of DLK1.
Gastrodin alleviates Aβ(25-35)-induced glycolytic dysfunction via activating PI3K/AKT/BACH1 signaling in Alzheimer's disease models.
Chronic prostatitis/chronic pelvic pain syndrome impairs erectile function by inducing apoptosis in a rat model of experimental autoimmune prostatitis.
CircSETD3 interrupts the bidirectional positive feedback of ErbB3 and Akt by sponging miR-4667-5p to inhibit colorectal cancer progression and cetuximab resistance.
AD16 Modulates Microglial Activation and Polarization to Mitigate Neuroinflammation in Ischemic Stroke Models Through α7nAChR-ERK-STAT3 Signaling.
Phellodendrine chloride alleviates gouty arthritis through IL-6/STAT3 signaling pathway.
Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration.
Design, synthesis, and antitumor activity of novel thioheterocyclic nucleoside derivatives by suppressing the c-MYC pathway.
AdipoR2 enhances adipocyte thermogenesis in Tibetan pigs via AMPK-ACC signaling.
STAT1 and STAT6 orchestrate Cbs transcription and transsulfur metabolism in microglia and contribute to parkinson's disease-related neuroinflammation.
TSPAN7 inhibits pancreatic cancer progression by suppressing DNA double-strand break repair and enhances sensitivity to immunochemotherapy.
HOXC4 promotes proliferation of endometriotic stromal cells via the SLIT2-ROBO1 axis.
Protocatechuic acid suppresses ferroptosis to protect against hypoxic-ischemic encephalopathy by targeting the HIF-1α/VEGFA axis.
Discovery of 2-Pyrazolylpyrimidinone Derivatives as New SPOP Inhibitors for Renal Cell Carcinoma Therapy.
Kai-Xin-San ameliorates fluoxetine-resistant depressive-like behaviors by modulating tryptophan-kynurenine metabolic homeostasis in a rodent model.
TRIB3 regulates Cx43 expression in human granulosa cells via the Wnt/β-catenin signaling pathway: an in vitro study.
Design, synthesis and biological evaluation of novel β-caryophyllene derivatives as potential anti-cancer agents through the ROS-mediated apoptosis pathway.
TBB inhibits CK2/PD-L1/EGFR pathway-mediated tumor progression.
CLDN4 palmitoylation promotes hepatic-to-biliary lineage transition and lenvatinib resistance in hepatocellular carcinoma.
The interaction between COX-2 and endoplasmic reticulum stress is involved in liver ischemia-reperfusion injury in mice.
SIRT5 alleviates oxidative stress of boar sperm induced by cryopreservation through IDH2 and SOD2 pathway.
Gut bacteria and the host synergies promote resveratrol metabolism and induce tolerance in ALD mice.
Tang Bi formula alleviates diabetic sciatic neuropathy via AMPK/PGC-1α/MFN2 pathway activation.
Pharmacological evaluation of physcion as a TRPV1 inhibitor with multimodal analgesic efficacy in experimental pain models.
Differences in macrophage pyroptosis and polarization induced by nano-/micro-calcium oxalate crystals.
Intermediate filament IFFO1 negatively regulates the migration of lung cancer cells by inhibiting the IQGAP3-Cdc42 interaction.
Consensus artificial intelligence-driven prognostic signature for predicting the prognosis of hepatocellular carcinoma: a multi-center and large-scale study.
Self-propelled smart nanomotors for enhanced mild photothermal therapy of tumors through autophagy modulation.
BSCL2 and CDK5 are two genes associated with circadian rhythm disturbance in Parkinson's disease.
Identification of a ferroptosis related genes signature and GDF15 contributing to a new perspective for the diagnosis of CRPC.
IL-17A's role in exacerbating radiation-induced lung injury: Autophagy impairment via the PP2A-mTOR pathway.
Impaired Iron-Sulfur Cluster Synthesis Induces Mitochondrial PARthanatos in Diabetic Cardiomyopathy.
GNF-5837 alleviates intervertebral disc ageing by upregulating glutathione peroxidase 7.
Diagnostic role of circulating long non-coding RNA LINC00312 in patients with non-small cell lung cancer: a retrospective study.
Cromolyn sodium reduces LPS-induced pulmonary fibrosis by inhibiting the EMT process enhanced by MC-derived IL-13.
Cordycepin Extracted from Cordyceps militaris mitigated CUMS-induced depression of rats via targeting GSK3β/β-catenin signaling pathway.
Elucidation of the mechanism of the Yinhua Miyanling Tablet against urinary tract infection based on a combined strategy of network pharmacology, multi-omics and molecular biology.
N(6)-methyladenosine in 28S rRNA promotes oncogenic mRNA translation and tyrosine catabolism.
Adipose mesenchymal stem cell-derived extracellular vesicles alleviate renal fibrosis by reducing epithelial-mesenchymal transition via the FOXS1/Wnt/β-catenin signaling pathway.
CFAP65 is essential for C2a projection integrity in axonemes: implications for organ-specific ciliary dysfunction and infertility.
SUMO-Specific Peptidase 5 Promotes Oesophageal Squamous Cell Carcinoma Growth through the NF-κB-SLC1A3 Axis.
DUX4-induced HSATII RNA accumulation drives protein aggregation impacting RNA processing pathways.
1-methyl-tryptophan improves anxiety-like behavior in colitis mice by inhibiting neuroinflammation, promoting cell regeneration, and decreasing apoptosis.
Two novel heterozygous HPDL variants in a Chinese family with a neurodevelopmental disorder with progressive spasticity and brain white matter abnormalities.
Both 20S and 19S proteasome components are essential for meiosis in male mice.
The Role of TRPV1/CGRP Pathway Activated by Prevotella melaninogenica in Pathogenesis of Oral Lichen Planus.
Microglia phagocytosis of PNNs mediates PV-positive interneuron dysfunction and associated gamma oscillations in neuroinflammation-induced cognitive impairment in mice.
AAV mediated carboxyl terminus of Hsp70 interacting protein overexpression mitigates the cognitive and pathological phenotypes of APP/PS1 mice.
AFP shields hepatocellular carcinoma from macrophage phagocytosis by regulating HuR-mediated CD47 translocation in cellular membrane.
Chronic environmental exposure to polystyrene microplastics increases the risk of nonalcoholic fatty liver disease.
E3 ubiquitin ligase CHIP facilitates cAMP and cGMP signalling cross-talk by polyubiquitinating PDE9A.
H(2)S Donor SPRC Ameliorates Ischemic Stroke by Upregulating CD24.
The PROTAC selectively degrading BCL-X(L) inhibits the growth of tumors and significantly synergizes with Paclitaxel.
SMURF1 leads to the β-catenin signaling-mediated progression of esophageal squamous carcinoma by losing PATZ1-induced CCNG2 transcription.
VNS facilitates the neurological function recovery after ischemia/reperfusion injury by regulating the A1/A2 polarization of astrocytes through the NMU-NMUR2 pathway.
PPARβ/δ Activation Improves Corticosterone-Induced Oxidative Stress Damage in Astrocytes by Targeting UBR5/ATM Signaling.
Melittin suppresses ovarian cancer growth by regulating SREBP1-mediated lipid metabolism.
Clofarabine induces tumor cell apoptosis, GSDME-related pyroptosis, and CD8(+) T-cell antitumor activity via the non-canonical P53/STING pathway.
CircGRB14 Inhibits Proliferation and Promotes Apoptosis of Granulosa Cells in Chicken Follicle Selection Through Sponging miR-12264-3p and miR-6660-3p.
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
Bridging the gap: investigating the role of phosphorylation at the serine 129 site of α-synuclein in VAPB-PTPIP51 interactions.
α-Cyperone Alleviates LPS-Induced Pyroptosis in Rat Aortic Endothelial Cells via the PI3K/AKT Signaling Pathway.
In vitro analysis of the molecular mechanisms of ursolic acid against ovarian cancer.
O-GlcNAcylation of DJ-1 suppresses ferroptosis in renal cell carcinoma by affecting the transsulfuration pathway.
Exploring macrophage and nerve interaction in endometriosis-associated pain: the inductive role of IL-33.
Structural Characterization of APSN from Astragalus membranaceus and Its Potential Therapeutic Effect on Immune Dysregulation and Tissue Damage.
p16(INK4a) promoted progress of MCT induced pulmonary hypertension via maintaining redox balance and autophagy pathway.
Eriodictyol-cisplatin coated nanomedicine synergistically promote osteosarcoma cells ferroptosis and chemosensitivity.
Inhibition of SCF(KDM2A)/USP22-dependent nuclear β-catenin ubiquitylation mediates cerebral ischemic tolerance.
Dihuang Yinzi improves scopolamine-induced learning and memory impairment by regulating plasma exosome-derived BDNF.
Antidepressant and anxiolytic effects of Wuling Capsule in CSDS mice: Alleviating HPA axis hyperactivity via the Nesfatin-1/NF-κB signaling pathway.
MDPAO1 peptide from human milk enhances brown adipose tissue thermogenesis and mitigates obesity.
PINK1 overexpression suppresses p38 MAPK/NF‑κB signaling to attenuate chondrocyte senescence in osteoarthritis.
Sodium-Glucose Cotransporter 2 Inhibitor Ameliorate Angiotensin II-Induced Hypertension and Vascular Injury by Upregulating FGF21.
Dietary baking soda (NaHCO(3)) therapy recovered urolithiasis-induced kidney injury in mice by inhibition of oxidative stress, pyroptosis, and inflammation through gut-kidney axis.
TM4SF1 as a Prognostic Biomarker and Therapeutic Target in Cervical Cancer.
Atf3 Deficiency Promotes Mesodermal Commitment and Enhances Endothelial Differentiation in Embryonic Stem Cells.
Integrated multi-omics analysis reveals TMEM147 as an immunosuppressive prognostic biomarker in LUAD.
Anti-tumor analysis of the RIG-I agonist in vitro and in vivo.
Chlormequat chloride inhibited thyroid hormone in the pregnant rats by regulating sodium/iodide symporter.
STC2 Serves as a Critical Hypoxic Effector in Keloid Pathogenesis by Orchestrating Fibroblasts Activation and ECM Remodelling.
A novel covalent inhibitor alleviates type 2 diabetes mellitus by restraining GSK-3β.
Low-Intensity pulsed ultrasound inhibits the ROS/NF-κB signaling pathway and improves inflammation in ovarian granulosa cells of PCOS rats.
Gut microbes-spinal connection is required for itch sensation.
Ferroptosis is important for Toxoplasma gondii replication and virulence in vitro and in vivo.
Elevated SNHG15 empowers keratinocytes hyperproliferation through activation of STAT3/Cyclin D1 axis in psoriasis.
CAPG enhances adipogenesis and inflammatory cytokine expression in adipocytes.
Andrographolide drives dual apoptosis and ferroptosis via caspase-3 and FACL4 in T-ALL cell lines.
Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain-Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model.
Transcriptome analysis reveals reduced lipid accumulation and mitochondrial metabolic remodeling in ADCY3-overexpressing adipocytes.
Multi-omics analysis reveals that ALYREF-mediated m(5)C modification promotes platinum resistance in ovarian cancer via the NSUN2/ALYREF/LGR4 axis.
GSDMD deficiency attenuates BPD by suppressing macrophage pyroptosis and promoting M2 polarization.
Activated oligoadenylate synthetase-ribonuclease L pathway promotes endothelial pyroptosis and impairs diabetic wound healing via thioredoxin-interacting protein m(6)A methylation.
EXOSC3 knockdown induces G1/S phase arrest to suppress hepatocellular carcinoma cell proliferation.
Cathepsin C-driven enhancement of neutrophil extracellular trap formation contributes to acute lung injury.
STAT2 Promotes Tumor Growth in Colorectal Cancer Independent of Type I IFN Receptor Signaling.
Discovery of a heterocyclic aromatic amide based P-gp inhibitor as coadjutant regulating autophagy against drug resistance in breast cancer.
Exercise-induced histone lactylation in monocyte-derived macrophages restores cardiac immune homeostasis and function in sepsis-induced cardiomyopathy.
β-caryolane derivatives as novel anti-colorectal cancer agents: synthesis and in vitro biological evaluation.
RalGAP complexes control secretion and primary cilia in pancreatic disease.
Cardiomyocyte-localized CCDC25 senses NET DNA to promote doxorubicin cardiotoxicity by activating autophagic flux.
An RNA G-quadruplex within the sclerostin 3' untranslated region enhances sclerostin expression by blocking miR-4648 binding.
Trimethylamine N-Oxide Mitigates Perioperative Neurocognitive Disorders via ANXA1 Nuclear Translocation and M2 Microglial Polarization in the Hippocampus.
Leber's hereditary optic neuropathy-associated ND1 3733G>C mutation ameliorates the mitochondrial quality control and cellular homeostasis.
Purinergic P2X7 receptor involves in anti-retinal photodamage effects of berberine.
Electroacupuncture regulates the P2X(7)R-NLRP3 inflammatory cascade to relieve decreased sensation on ocular surface of type 2 diabetic rats with dry eye.
Cardiopulmonary Bypass-Induced IL-17A Aggravates Caspase-12-Dependent Neuronal Apoptosis Through the Act1-IRE1-JNK1 Pathway.
RIPK1 senses S-adenosylmethionine scarcity to drive cell death and inflammation.
Dimethyl fumarate improves non-alcoholic fatty liver disease by regulating SIRT1 signal to inhibit MAMs over-enrichment.
PGRP-S promotes hepatocellular carcinoma progression via MAPK/ERK pathway by interaction with TTC1.
Targeting phagocytosis for amyloid-β clearance: implications of morphology remodeling and microglia activation probed by bifunctional chimaeras.
Construction of lactylation (LA) risk signature in prostate cancer based on 4D fast DIA L-lactated quantitative genomics.
Anti-Obesity Effects of Pea Peptides Modified by Steam Explosion on Obese Mice: Regulation of Gut Microbiota and Glucose Metabolism.
Anterior cingulate cortex mediates the comorbidity between colorectal cancer and depression-like behaviors.
Cyclooxygenase-1 deletion in 5 × FAD mice protects against microglia-induced neuroinflammation and mitigates cognitive impairment.
Oncogenic GOPC-ROS1 fusion promotes the formation of lymphatic malformations by impairing tight junction and its crizotinib resistance through repressing ferroptosis.
High expression of LIMD2 predicts a poor prognosis and promotes migration of colon cancer cells.
GDF15 attenuates myocardial hypoxic injury by inhibiting mitochondrial damage through BNIP3 pathway.
Chondroitin sulfate protects against synaptic impairment caused by fluorosis through the Erk1/2-MMP-9 signaling pathway.
MOSPD1 facilitates fatty acid metabolism and gastric cancer progression by promoting the MAPK pathway.
TFAP4 Regulation of MCM5 Activates the PI3K/AKT Pathway to Promote Invasion and Metastasis of Gastric Cancer.
The property of larval cells of the scleractinian coral, Acropora tenuis, deduced from in vitro cultured cells.
Targeted sonodynamic therapy induces tumor cell quasi-immunogenic ferroptosis and macrophage immunostimulatory autophagy in glioblastoma.
Mycoplasma ovipnuemoniae impairs the immune response of sheep and suppresses neutrophil function by inhibiting S100A9.
Integrative Multi-Omics Approaches Reveal Selectivity Profiles and Molecular Mechanisms of FIIN-2, a Covalent FGFR Inhibitor.
The INO80E at 16p11.2 locus increases risk of schizophrenia in humans and induces schizophrenia-like phenotypes in mice.
Tanshinone IIA Ameliorates Myocardial Ischemia-Reperfusion Injury via Activating HDAC1-Repressed Nrf2-xCT/Gpx4/HO-1 Axis.
The African swine fever virus gene MGF_360-4L inhibits interferon signaling by recruiting mitochondrial selective autophagy receptor SQSTM1 degrading MDA5 antagonizing innate immune responses.
Lacc1-engineered extracellular vesicles reprogram mitochondrial metabolism to alleviate inflammation and cartilage degeneration in TMJ osteoarthritis.
Inhaled exogenous thymosin beta 4 suppresses bleomycin-induced pulmonary fibrosis in mice via TGF-β1 signalling pathway.
FAM20B-Catalyzed Glycosylation Regulates the Chondrogenic and Osteogenic Differentiation of the Embryonic Condyle by Controlling IHH Diffusion and Release.
LAMP2A-mediated neuronal hyperexcitability by enhancing NKAβ1 degradation underlies depression-induced allodynia.
GAMT facilitates tumor progression via inhibiting p53 in clear cell renal cell carcinoma.
The interaction between IL-33 and TRIM28 in the regulation of macrophage polarization in an ST2-independent manner.
Troxerutin suppresses the stemness of osteosarcoma via the CD155/SRC/β-catenin signaling axis.
Preclinical evaluation of AGT mRNA replacement therapy for primary hyperoxaluria type I disease.
Development of an iridium complex fluorescent probe for FGF21 protein labeling and tracking.
Aquaporin 9 downregulation in KRAS(G12V) colorectal cancer and associated with increased proliferation and decreased apoptosis in cancer cells.
In vitro susceptibility of differentiated SH-SY5Y human neuroblastoma cells to herpes simplex virus type 1 and Japanese encephalitis virus infection.
KGF-2 Alleviates Dry Eye Disease by Regulating the HMGB1/TLR4 Pathway.
Idebenone improves mitochondrial respiratory activity and attenuates oxidative damage via the SIRT3-SOD2 pathway in a prion disease cell model.
Genome-Wide Mendelian Randomization Identifies Ferroptosis-Related Drug Targets for Alzheimer's Disease.
Electroacupuncture Improves Cardiac Function via Inhibiting Sympathetic Remodeling Mediated by Promoting Macrophage M2 Polarization in Myocardial Infarction Mice.
Comparative Analysis of the Therapeutic Effects of MSCs From Umbilical Cord, Bone Marrow, and Adipose Tissue and Investigating the Impact of Oxidized RNA on Radiation-Induced Lung Injury.
USP10 promotes pancreatic ductal adenocarcinoma progression by attenuating FOXC1 protein degradation to activate the WNT signaling pathway.
Identification and development of Tetra-ARMS PCR-based screening test for a genetic variant of OLA1 (Tyr254Cys) in the human failing heart.
Apelin-13-Loaded Macrophage Membrane-Encapsulated Nanoparticles for Targeted Ischemic Stroke Therapy via Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis.
SIRT2 Promotes NLRP3-Mediated Microglia Pyroptosis and Neuroinflammation via FOXO3a Pathway After Subarachnoid Hemorrhage.
Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activating the Nrf2/HO-1 pathway.
Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.
ATP5J regulates microglial activation via mitochondrial dysfunction, exacerbating neuroinflammation in intracerebral hemorrhage.
Identification and validation of efferocytosis-related biomarkers for the diagnosis of metabolic dysfunction-associated steatohepatitis based on bioinformatics analysis and machine learning.
(+)-catechin protects PC12 cells against CORT-induced oxidative stress and pyroptosis through the pathways of PI3K/AKT and Nrf2/HO-1/NF-κB.
APP-CD74 axis mediates endothelial cell-macrophage communication to promote kidney injury and fibrosis.
Synergistic antitumor activity of baicalein combined with almonertinib in almonertinib-resistant non-small cell lung cancer cells through the reactive oxygen species-mediated PI3K/Akt pathway.
Metrnl inhibits choroidal neovascularization by attenuating the choroidal inflammation via inactivating the UCHL-1/NF-κB signaling pathway.
Xiasangju alleviate metabolic syndrome by enhancing noradrenaline biosynthesis and activating brown adipose tissue.
Edaravone dexborneol attenuates oxidative stress in experimental subarachnoid hemorrhage via Keap1/Nrf2 signaling pathway.
TRIM28 facilitates type I interferon activation by targeting TBK1.
A novel brown adipocytes-related gene signature predicts and validates prognosis and immune infiltration of clear cell renal cell carcinoma.
Abnormal mitochondrial iron metabolism damages alveolar type II epithelial cells involved in bleomycin-induced pulmonary fibrosis.
Towards modelling tick-virus interactions using the weakly pathogenic Sindbis virus: Evidence that ticks are competent vectors.
Matrix metalloproteinase-8 regulates dendritic cell tolerance in late polymicrobial sepsis via the nuclear factor kappa-B p65/β-catenin pathway.
PLAUR facilitates the progression of clear cell renal cell carcinoma by activating the PI3K/AKT/mTOR signaling pathway.
PLEK2: a potential biomarker for metastasis and prognostic evaluation in uveal melanoma.
N6-methyladenosine triggers renal fibrosis via enhancing translation and stability of ZEB2 mRNA.
A novel senolytic drug for pulmonary fibrosis: BTSA1 targets apoptosis of senescent myofibroblasts by activating BAX.
Systematic identification of post-transcriptional regulatory modules.
SIRT1 Regulates Mitochondrial Damage in N2a Cells Treated with the Prion Protein Fragment 106-126 via PGC-1α-TFAM-Mediated Mitochondrial Biogenesis.
Key subdomains of mesencephalic astrocyte-derived neurotrophic factor attenuate myocardial ischemia/reperfusion injury by JAK1/STAT1/NF-κB signaling pathway.
GRP78/IRE1 and cGAS/STING pathway crosstalk through CHOP facilitates iodoacetic acid-mediated testosterone decline.
Developing diagnostic biomarkers for Alzheimer's disease based on histone lactylation-related gene.
Duck hepatitis A virus 1-encoded 2B protein disturbs ion and organelle homeostasis to promote NF-κB/NLRP3-mediated inflammatory response.
The Delayed Turnover of Proteasome Processing of Myocilin upon Dexamethasone Stimulation Introduces the Profiling of Trabecular Meshwork Cells' Ubiquitylome.
Electroacupuncture enhances cerebral blood perfusion by inhibiting HIF-1α in rat subarachnoid hemorrhage.
Hsa_circ_0000825 promotes the progression of laryngeal squamous cell carcinoma by sponging miR-766 and interacting with ELAVL1.
Upregulated SKP2 Empowers Epidermal Proliferation Through Downregulation of P27 Kip1.
Prebiotic stachyose inhibits PRDX5 activity and castration-resistant prostate cancer development.
Dipeptidyl peptidase 4: A predictor of ferroptosis in ulcerative colitis.
Global acetylome profiling indicates EPA impedes but OA promotes prostate cancer motility through altered acetylation of PFN1 and FLNA.
ITCH inhibits alkaliptosis in human pancreatic cancer cells through YAP1-dependent SLC16A1 activation.
Acovenosigenin A β-glucoside mediates JAK2-STAT3 signaling pathway by targeting GP130 in A549 and H460 cells based on integrative analysis of transcriptome and proteome and biological verification.
Paeoniflorin suppresses ferroptosis after traumatic brain injury by antagonizing P53 acetylation.
Effect of dapagliflozin on pulmonary vascular remodeling in rats with chronic hypoxic pulmonary arterial hypertension.
Astaxanthin Alleviates Chronic Prostatitis via the ERK1/2 Signaling Pathway: Evidence from Network Pharmacology and Experimental Validation.
Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation.
Increased expression of mesencephalic astrocyte-derived neurotrophic factor (MANF) contributes to synapse loss in Alzheimer's disease.
Exogenous hydrogen sulfide enhances myogenic differentiation of C2C12 myoblasts under high palmitate stress.
Discovery of Potent Covalent CRM1 Inhibitors Via a Customized Structure-Based Virtual Screening Pipeline and Bioassays.
Discovery of SIRT1-Activating Hydrogen Sulfide Donating Derivatives for Efficient Resistant of Myocardial Ischemic Injury.
A comprehensive analysis of CEBPA on prognosis and function in uterine corpus endometrial carcinoma.
The LncRNA6524/miR-92a-2-5p/Dvl1/Wnt/β-catenin axis promotes renal fibrosis in the UUO mouse model.
miR‑155 promotes an inflammatory response in HaCaT cells via the IRF2BP2/KLF2/NF‑κB pathway in psoriasis.
FOXO1-mTOR pathway in vascular pericyte regulates the formation of type H vessels to control bone metabolism.
GTF2H5 Identified as a crucial synthetic lethal target to counteract chemoresistance in colorectal cancer.
PDZD8 Augments Endoplasmic Reticulum-Mitochondria Contact and Regulates Ca2+ Dynamics and Cypd Expression to Induce Pancreatic β-Cell Death during Diabetes.
A two-pronged approach to inhibit ferroptosis of MSCs caused by the iron overload in postmenopausal osteoporosis and promote osseointegration of titanium implant.
Prevotella melaninogenica disrupted oral epithelial barrier function via myosin light chain kinase.
Protective effects of bioactive components targeting β2-adrenergic receptors and muscarinic-3 acetylcholine receptor in Zhisou San on ovalbumin-induced allergic asthma.
Mesenchymal stem cells improve depressive disorder via inhibiting the inflammatory polarization of microglia.
Accelerating diabetic wound healing with Ramulus Mori (Sangzhi) alkaloids via NRF2/HO-1/eNOS pathway.
S. glabra exerts anti-lung cancer effects by inducing ferroptosis and anticancer immunity.
Trans-resveratrol mitigates miR-204-3p mediated progression of allergic rhinitis by regulating the EGLN3/HIF-1α/IL33/ST2 signalling pathway.
HES1 revitalizes the functionality of aged adipose-derived stem cells by inhibiting the transcription of STAT1.
Involvement of sphingosine-1-phosphate receptor 1 in pain insensitivity in a BTBR mouse model of autism spectrum disorder.
Oxidative Injury to Lung Mitochondrial DNA is a Key Contributor for the Development of Chemical Lung Injury.
KLF4 promotes cisplatin resistance by activating mTORC1 signaling in ovarian cancer.
A novel multifunctional nanocomposite hydrogel orchestrates the macrophage reprogramming-osteogenesis crosstalk to boost bone defect repair.
Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation.
A peptide against the N-terminus of myristoylated alanine-rich C kinase substrate promotes neuronal differentiation in SH-SY5Y human neuroblastoma cells.
Itaconate inhibits corticosterone-induced necroptosis and neuroinflammation via up-regulating menin in HT22 cells.
PMP2 regulates myelin thickening and ATP production during remyelination.
ER-tethered RNA-binding protein controls NADPH oxidase translation for hydrogen peroxide homeostasis.
EMX2 inhibits clear cell renal cell carcinoma progress via modulating Akt/FOXO3a pathway.
Follicular fluid-derived exosomal LncRNA LIPE-AS1 modulates steroid metabolism and survival of granulosa cells leading to oocyte maturation arrest in polycystic ovary syndrome.
PLCE1 enhances mitochondrial dysfunction to promote GSDME-mediated pyroptosis in doxorubicin-induced cardiotoxicity.
D-mannose alleviates intervertebral disc degeneration through glutamine metabolism.
PD-1/PD-L1 axis is involved in the interaction between microglial polarization and glioma.
Electroacupuncture modulates the TLR4-NF-κB inflammatory signaling pathway to attenuate ocular surface inflammation in dry eyes of type 2 diabetic rats.
Nitazoxanide protects against experimental ulcerative colitis through improving intestinal barrier and inhibiting inflammation.
Transcriptomics confirms IRF1 as a key regulator of pyroptosis in diabetic retinopathy.
Targeted degradation of oncogenic BCR-ABL by silencing the gene of NEDD8 E3 ligase RAPSYN.
Oxypeucedanin hydrate alleviates rheumatoid arthritis by inhibiting the TLR4-MD2/NF-κB/MAPK signaling axis.
Esculin suppresses the PERK-eIF2α-CHOP pathway by enhancing SIRT1 expression in oxidative stress-induced rat chondrocytes, mitigating osteoarthritis progression in a rat model.
The disrupting effect of chlormequat chloride on growth hormone is associated with pregnancy.
Crocin Inhibits Orbital Fibroblasts Fibrosis in Thyroid-Associated Ophthalmopathy.
SESN1 functions as a new tumor suppressor gene via Toll-like receptor signaling pathway in neuroblastoma.
OTUD7B knockdown inhibits the proliferation and stemness of breast cancer cells by destabilizing FOXM1.
ACOX1 deficiency-induced lipid metabolic disorder facilitates chronic interstitial fibrosis development in renal allografts.
RSK4 promotes the macrophage recruitment and M2 polarization in esophageal squamous cell carcinoma.
Enhanced glutathione production protects against zearalenone-induced oxidative stress and ferroptosis in female reproductive system.
DTTZ suppresses ferroptosis and reverses mitochondrial dysfunction in normal tissues affected by chemotherapy.
Genome-wide analyses reveal the regulatory roles of DNA methylation-regulated alternative promoter transcripts in breast cancer.
The RNA m(6)A reader IGF2BP3 regulates NFAT1/IRF1 axis-mediated anti-tumor activity in gastric cancer.
Pan-cancer integrated analysis of ANKRD1 expression, prognostic value, and potential implications in cancer.
RFX1 regulates foam cell formation and atherosclerosis by mediating CD36 expression.
Discovery and verification of mmu_Circ_26986/hsa_Circ_0072463 as a potential biomarker and intervention target for sepsis-associated acute kidney injury.
Securin acetylation prevents precocious separase activation and premature sister chromatid separation.
Piperine promotes PI3K/AKT/mTOR-mediated gut-brain autophagy to degrade α-Synuclein in Parkinson's disease rats.
An intranasal influenza virus vector vaccine protects against Helicobacter pylori in mice.
Metformin switches cell death modes to soothe the apical periodontitis via ZBP1.
YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia.
Design, synthesis, and bioactivity evaluation of novel indole-selenide derivatives as P-glycoprotein inhibitors against multi-drug resistance in MCF-7/ADR cell.
Endoplasmic reticulum stress impedes regulated secretion by governing key exocytotic and granulogenic molecular switches.
Antidepressant fluoxetine alleviates colitis by reshaping intestinal microenvironment.
Mefloquine enhances the efficacy of anti-PD-1 immunotherapy via IFN-γ-STAT1-IRF1-LPCAT3-induced ferroptosis in tumors.
IL-35 ameliorates lipopolysaccharide-induced endothelial dysfunction by inhibiting endothelial-to-mesenchymal transition.
The mechanism of EGFL7 regulating neovascularization in diabetic retinopathy through the PI3K/AKT/VEGFA pathway.
Arecoline induces neurotoxicity in HT22 cells via the promotion of endoplasmic reticulum stress and downregulation of the Nrf2/HO-1 pathway.
LUC7L3 is a downstream factor of SRSF1 and prevents genomic instability.
Real time monitoring peripheral nerve function with ICG and BDA-ICG by NIR-II fluorescence imaging.
Conditional deficiency of Rho-associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice.
HOXB2 promotes cisplatin resistance by upregulating lncRNA DANCR in ovarian cancer.
Bu-Shen-Ning-Xin decoction inhibits macrophage activation to ameliorate premature ovarian insufficiency-related osteoimmune disorder via FSH/FSHR pathway.
Increasing GSH-Px Activity and Activating Wnt Pathway Promote Fine Wool Growth in FGF5-Edited Sheep.
A pan-KRAS degrader for the treatment of KRAS-mutant cancers.
Tumor cell-released autophagosomes (TRAPs) induce PD-L1-decorated NETs that suppress T-cell function to promote breast cancer pulmonary metastasis.
PWP1 is overexpressed in hepatocellular carcinoma and facilitates liver cancer cell proliferation.
Frataxin deficiency shifts metabolism to promote reactive microglia via glucose catabolism.
NKAIN1, as an oncogene, promotes the proliferation and metastasis of breast cancer, affecting its prognosis.
Transformation of A1/A2 Astrocytes Participates in Brain Ischemic Tolerance Induced by Cerebral Ischemic Preconditioning via Inhibiting NDRG2.
Quercetin prevented diabetic nephropathy by inhibiting renal tubular epithelial cell apoptosis via the PI3K/AKT pathway.
MicroRNA-322-5p targeting Smurf2 regulates the TGF-β/Smad pathway to protect cardiac function and inhibit myocardial infarction.
PPARα phosphorylation regulates colorectal tumor immune escape.
PC (16:0/14:0) ameliorates hyperoxia-induced bronchopulmonary dysplasia by upregulating claudin-1 and promoting alveolar type II cell repair.
Preventive effect of propolis on cognitive decline in Alzheimer's disease model mice.
The EPRS-ATF4-COLI pathway axis is a potential target for anaplastic thyroid carcinoma therapy.
Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation.
Alcohol- and Low-Iron Induced Changes in Antioxidant and Energy Metabolism Associated with Protein Lys Acetylation.
Lipid-associated macrophages reshape BAT cell identity in obesity.
Procyanidin C1 inhibits bleomycin-induced pulmonary fibrosis in mice by selective clearance of senescent myofibroblasts.
Initial Characterization of WDR5B Reveals a Role in the Proliferation of Retinal Pigment Epithelial Cells.
Genome-scale exon perturbation screens uncover exons critical for cell fitness.
Synthesis and Characterization of a Novel PET Tracer for Noninvasive Evaluation of FGL1 Status in Tumors.
Circular RNA circXPO1 Promotes Multiple Myeloma Progression by Regulating miR-495-3p/DNA Damage-Induced Transcription 4 Axis.
Aristolochic acid I aggravates oxidative stress-mediated apoptosis by inhibiting APE1/Nrf2/HO-1 signaling.
HSP90β regulates EAAT2 expression and participates in ischemia‑reperfusion injury in rats.
Ailanthone synergizes with PARP1 inhibitor in tumour growth inhibition through crosstalk of DNA repair pathways in gastric cancer.
Identification of potential miR‑155 target genes in epidermal immune microenvironment of atopic dermatitis patients and their inflammatory effects on HaCaT cells.
MicroRNA-124 conducts neuroprotective effect via inhibiting AK4/ATF3 after subarachnoid hemorrhage.
Hydrogen sulfide attenuates depression-like behaviours in Parkinson's disease model rats by improving synaptic plasticity in a hippocampal Warburg effect-dependent manner.
Amyloid pathology reduces ELP3 expression and tRNA modifications leading to impaired proteostasis.
Inulin alters gut microbiota to alleviate post-stroke depressive-like behavior associated with the IGF-1-mediated MAPK signaling pathway.
Lycopene protects against ionizing radiation-induced testicular damage by inhibition of apoptosis and mitochondrial dysfunction.
Mitochondria-derived peptide is an effective target for treating streptozotocin induced painful diabetic neuropathy through induction of activated protein kinase/peroxisome proliferator-activated receptor gamma coactivator 1alpha -mediated mitochondrial biogenesis.
High-fat diet-induced L-saccharopine accumulation inhibits estradiol synthesis and damages oocyte quality by disturbing mitochondrial homeostasis.
Varicella zoster virus glycoprotein E facilitates PINK1/Parkin-mediated mitophagy to evade STING and MAVS-mediated antiviral innate immunity.
TBC1D1 represses glioma progression by altering the integrity of the cytoskeleton.
α-Synuclein reduces acetylserotonin O-methyltransferase mediated melatonin biosynthesis by microtubule-associated protein 1 light chain 3 beta-related degradation pathway.
FBXO28 promotes cell proliferation, migration and invasion via upregulation of the TGF-beta1/SMAD2/3 signaling pathway in ovarian cancer.
DDX60 Promotes Migration and Invasion of Head and Neck Squamous Cell Carcinoma Cell through the NF-κB/IFI27 Signaling Pathway.
Discovery of (quinazolin-6-yl)benzamide derivatives containing a 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety as potent reversal agents against P-glycoprotein-mediated multidrug resistance.
Preliminary study on the role of the CSMD2 gene in bladder cancer.
GDF11 mediates H(2)S to prevent chronic stress-induced cognitive impairment by reducing hippocampal NLRP3/caspase-1-dependent pyroptosis.
Mechanism of synergistic inhibitory effect of benzyl isothiocyanate and zoledronic acid combination on breast cancer induction of osteoclast differentiation.
Aucubin provides protection against cerebral ischaemia-reperfusion injury by suppressing neuronal apoptosis, oxidative stress, and inflammation through the modulation of the AKT-GSK-3β-Nrf2 signal cascade.
Circular RNA RHBDD1 regulates tumorigenicity and ferroptosis in colorectal cancer by mediating the ELAVL1/SCD mRNA interaction.
Single-cell multi-omics profiling of human preimplantation embryos identifies cytoskeletal defects during embryonic arrest.
CDC123 promotes Hepatocellular Carcinoma malignant progression by regulating CDKAL1.
A prognostic model based on Scissor(+) cancer associated fibroblasts identified from bulk and single cell RNA sequencing data in head and neck squamous cell carcinoma.
Discovery of PRDM16-Mediated TRPA1 Induction as the Mechanism for Low Tubulo-Interstitial Fibrosis in Diabetic Kidney Disease.
CEBPA Overexpression Enhances β-Cell Proliferation and Survival.
Warm Acupuncture Reduces Pain and Inflammation in Rats with Lumbar Disc Herniation Induced by Autologous Nucleus Pulposus Transplantation via Regulating p38MAPK/NF-κB Pathway.
Identification of hypoxia- and immune-related biomarkers in patients with ischemic stroke.
Specific inhibition of TET1 in the spinal dorsal horn alleviates inflammatory pain in mice by regulating synaptic plasticity.
Electroacupuncture stimulation ameliorates cognitive impairment induced by long-term high-fat diet by regulating microglial BDNF.
MiR-145-5p overexpression rejuvenates aged adipose stem cells and accelerates wound healing.
Calcitonin gene-related peptide attenuated discogenic low back pain in rats possibly via inhibiting microglia activation.
Tanshinone IIA alleviates inflammation-induced skeletal muscle atrophy by regulating mitochondrial dysfunction.
M2 macrophages promote subconjunctival fibrosis through YAP/TAZ signalling.
Tumour cell-released autophagosomes promote lung metastasis by upregulating PD-L1 expression in pulmonary vascular endothelial cells in breast cancer.
Attenuation of high-fat diet-induced weight gain by apolipoprotein A4.
Foxk1 promotes bone formation through inducing aerobic glycolysis.
Sorafenib and SIAIS361034, a novel PROTAC degrader of BCL-x(L), display synergistic antitumor effects on hepatocellular carcinoma with minimal hepatotoxicity.
Sulforaphane acts through the NFE2L2/AMPK signaling pathway to protect boar spermatozoa from cryoinjury by activating antioxidant defenses.
Hymenolepis nana antigens alleviate ulcerative colitis by promoting intestinal stem cell proliferation and differentiation via AhR/IL-22 signaling pathway.
Nervous necrosis virus induced vacuolization is a Rab5- and actin-dependent process.
Gastrodia elata specific miRNA attenuates neuroinflammation via modulating NF-κB signaling pathway.
OTUD1 regulates cytokine expression and related pathways in goose fatty liver by promoting deubiquitination of its target proteins.
α-linolenic acid mitigates microglia-mediated neuroinflammation of schizophrenia in mice by suppressing the NF-κB/NLRP3 pathway via binding GPR120-β-arrestin 2.
The Mitochondrial Fusion Promoter M1 Mitigates Cigarette Smoke-Induced Airway Inflammation and Oxidative Stress via the PI3K-AKT Signaling Pathway.
Isoliquiritigenin alleviates neuropathic pain by reducing microglia inflammation through inhibition of the ERK signaling pathway and decreasing CEBPB transcription expression.
Colorectal cancer cells establish metabolic reprogramming with cancer-associated fibroblasts (CAFs) through lactate shuttle to enhance invasion, migration, and angiogenesis.
Desuccinylation of TBK1 by SIRT5 regulates inflammatory response of macrophages in sepsis.
Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma.
OSGEP regulates islet β-cell function by modulating proinsulin translation and maintaining ER stress homeostasis in mice.
Fish Snx27 promotes viral products by modulating the innate immune response and exosomal machinery.
Comparison of Endoplasmic Reticulum Stress and Pyroptosis Induced by Pathogenic Calcium Oxalate Monohydrate and Physiologic Calcium Oxalate Dihydrate Crystals in HK-2 Cells: Insights into Kidney Stone Formation.
Cannabidiol Suppresses Metastatic Castration-Resistant Prostate Cancer Progression and Recurrence through Modulating Tryptophan Catabolism.
Pharmacological Inhibition of Astrocytic Transglutaminase 2 Facilitates the Expression of a Neurosupportive Astrocyte Reactive Phenotype in Association with Increased Histone Acetylation.
The essential role of TTC28 in maintaining chromosomal stability via HSPA8 chaperone-mediated autophagy.
Hyaluronic acid-modified extracellular vesicles for targeted doxorubicin delivery in hepatocellular carcinoma.
Baicalein suppresses Coxsackievirus B3 replication by inhibiting caspase-1 and viral protease 2A.
Hunnivirus structural protein VP2 inhibits beta interferon production by targeting the IRF3 essential modulator.
Permethrin exposure impacts zebrafish lipid metabolism via the KRAS-PPAR-GLUT signaling pathway, which is mediated by oxidative stress.
Celastrol alleviates subconjunctival fibrosis induced by silicone implants mimicking glaucoma surgery.
A ROS-responsive and scavenging hydrogel for postoperative abdominal adhesion prevention.
Carnosic Acid: A Novel Selective Inhibitor of ERAP1 by Direct Binding and Its Modulation of Antigen Processing and Presentation.
Exome-wide association study identifies KDELR3 mutations in extreme myopia.
Micro-Infusion of 5-HT1a Receptor Antagonists into the Ventral Subiculum Ameliorate MK-801 Induced Schizophrenia-Like Behavior in Rats.
PERK inhibitor (ISRIB) improves depression-like behavior by inhibitions of HPA-axis over-activation in mice exposed to chronic restraint stress.
Cystathionine Gamma-Lyase Regulates TNF-α-Mediated Injury Response in Human Colonic Epithelial Cells and Colonoids.
The role of chromatin modulator DPY30 in glucose metabolism of colorectal cancer cells.
Lactate promotes microglial scar formation and facilitates locomotor function recovery by enhancing histone H4 lysine 12 lactylation after spinal cord injury.
OTU deubiquitinase, ubiquitin aldehyde binding 2 (OTUB2) modulates the stemness feature, chemoresistance, and epithelial-mesenchymal transition of colon cancer via regulating GINS complex subunit 1 (GINS1) expression.
A pro-metastatic tRNA fragment drives aldolase A oligomerization to enhance aerobic glycolysis in lung adenocarcinoma.
Effect of X-ray irradiation on renal excretion of bestatin through down-regulating organic anion transporters via the vitamin D receptor in rats.
Electroacupuncture negatively regulates the Nesfatin-1/ERK/CREB pathway to alleviate HPA axis hyperactivity and anxiety-like behaviors caused by surgical trauma.
Integrating bulk and single-cell sequencing reveals metastasis-associated CAFs in head and neck squamous cell carcinoma.
Acetylation-dependent deubiquitinase USP26 stabilizes BAG3 to promote breast cancer progression.
FGF2 promotes the proliferation of injured granulosa cells in premature ovarian failure via Hippo-YAP signaling pathway.
Silencing lncRNA-DARS-AS1 suppresses nonsmall cell lung cancer progression by stimulating miR-302a-3p to inhibit ACAT1 expression.
CRISPR/Cas9 based gene editing of Frizzled class receptor 6 (FZD6) reveals its role in depressive symptoms through disrupting Wnt/β-catenin signaling pathway.
Mechanism of acupuncture in attenuating cerebral ischaemia-reperfusion injury based on nuclear receptor coactivator 4 mediated ferritinophagy.
Icariin alleviates renal inflammation and tubulointerstitial fibrosis via Nrf2-mediated attenuation of mitochondrial damage.
Citric acid promotes SPARC release in pancreatic cancer cells and inhibits the progression of pancreatic tumors in mice on a high-fat diet.
A novel and ubiquitous miRNA-involved regulatory module ensures precise phosphorylation of RNA polymerase II and proper transcription.
Clock knockout in inhibitory neurons reduces predisposition to epilepsy and influences anxiety-like behaviors in mice.
Human amniotic mesenchymal stromal cell-derived exosomes promote neuronal function by inhibiting excessive apoptosis in a hypoxia/ischemia-induced cerebral palsy model: A preclinical study.
HSPA4 upregulation induces immune evasion via ALKBH5/CD58 axis in gastric cancer.
Short-term regulation of TSFM level does not alter amyloidogenesis and mitochondrial function in type-specific cells.
Evolutionary genetics of pulmonary anatomical adaptations in deep-diving cetaceans.
Identification of ferroptosis related genes and pathways in prostate cancer cells under erastin exposure.
Static magnetic field-induced IL-6 secretion in periodontal ligament stem cells accelerates orthodontic tooth movement.
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression.
The role of FPR2-mediated ferroptosis in formyl peptide-induced acute lung injury against endothelial barrier damage and protective effect of the mitochondria-derived peptide MOTS-c.
PEI, a new transfection method, augments the inhibitory effect of RBM5 on prostate cancer.
Phosphoglycerate mutase 5 exacerbates liver ischemia-reperfusion injury by activating mitochondrial fission.
Germline USP36 Mutation Confers Resistance to EGFR-TKIs by Upregulating MLLT3 Expression in Patients with Non-Small Cell Lung Cancer.
Circulating THBS1: A Risk Factor for Nonalcoholic Fatty Liver Disease in Obese Children.
Absent in melanoma 2 attenuates proliferation and migration and promotes apoptosis of human colorectal cancer cells by activating P38MAPK signaling pathway.
Penfluroidol Attenuates the Imbalance of the Inflammatory Response by Repressing the Activation of the NLRP3 Inflammasome and Reduces Oxidative Stress via the Nrf2/HO-1 Signaling Pathway in LPS-Induced Macrophages.
S100 Calcium Binding Protein A16 Promotes Cell Proliferation by triggering LATS1 ubiquitin degradation mediated by CUL4A ligase to inhibit Hippo pathway in Glioma development.
XPOT Disruption Suppresses TNBC Growth through Inhibition of Specific tRNA Nuclear Exportation and TTC19 Expression to Induce Cytokinesis Failure.
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
Sodium Butyrate Ameliorates Type 2 Diabetes-Related Sarcopenia Through IL-33-Independent ILC2s/IL-13/STAT3 Signaling Pathway.
Electroacupuncture alleviates perioperative hypothalamus-pituitary-adrenal axis dysfunction via circRNA-miRNA-mRNA networks.
Prognostic values of Annexins and validation of the influence on cell proliferation, migration, and invasion in uveal melanoma.
HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication.
Neutrophil infiltration associated genes on the prognosis and tumor immune microenvironment of lung adenocarcinoma.
Porcine epidemic diarrhea virus causes diarrhea by activating EGFR to regulates NHE3 activity and mobility on plasma membrane.
Weight bearing training alleviates muscle atrophy and pyroptosis of middle-aged rats.
The overexpression of actin related protein 2/3 complex subunit 1B(ARPC1B) promotes the ovarian cancer progression via activation of the Wnt/β-catenin signaling pathway.
Selenomethionine against titanium particle-induced osteolysis by regulating the ROS-dependent NLRP3 inflammasome activation via the β-catenin signaling pathway.
Pan-cancer analysis of Krüppel-like factor 3 and its carcinogenesis in pancreatic cancer.
Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis via the p38/p53/p21 pathway.
Application of a JEG-3 organoid model to study HLA-G function in the trophoblast.
Grouper cGAS is a negative regulator of STING-mediated interferon response.
Tsp-1(+) microglia attenuate retinal neovascularization by maintaining the expression of Smad3 in endothelial cells through exosomes with decreased miR-27a-5p.
Targeting plasmodium α-tubulin-1 to block malaria transmission to mosquitoes.
Inhibition of Hypothalamic FTO Activates STAT3 Signal through ERK1/2 Associated with Reductions in Food Intake and Body Weight.
Combined effects of EMP and RF field on emotional behavior in mice.
The protective role of EP300 in monocrotaline-induced pulmonary hypertension.
Effect of renal denervation on cardiac remodelling and function in rats with chronic intermittent hypoxia.
Aβ Induces Neuroinflammation and Microglial M1 Polarization via cGAS-STING-IFITM3 Signaling Pathway in BV-2 Cells.
DELE1 oligomerization promotes integrated stress response activation.
STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1(+) NK cells.
Optineurin tunes outside-in signaling to regulate lysosome biogenesis and phagocytic clearance in the retina.
Steroidal saponins PPI/CCRIS/PSV induce cell death in pancreatic cancer cell through GSDME-dependent pyroptosis.
MicroRNA miR-223 modulates NLRP3 and Keap1, mitigating lipopolysaccharide-induced inflammation and oxidative stress in bovine mammary epithelial cells and murine mammary glands.
EP300 promotes ferroptosis via HSPA5 acetylation in pancreatic cancer.
Upregulation of HDAC9 in hippocampal neurons mediates depression-like behaviours by inhibiting ANXA2 degradation.
FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer.
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production.
Antigenic variation in hemagglutinin-neuraminidase of Newcastle disease virus isolated from Tibet, China.
Glycogen synthase kinase 3 controls T-cell exhaustion by regulating NFAT activation.
CALHM2 V136G polymorphism reduces astrocytic ATP release and is associated with depressive symptoms and Alzheimer's disease risk.
Acetyl-coenzyme A acetyltransferase 1 promotes brown adipogenesis by activating the AMPK-PGC1α signaling pathway.
A high-throughput Gaussia luciferase reporter assay for screening potential gasdermin E activators against pancreatic cancer.
Plasma exosomes induce inflammatory immune response in patients with acute myocardial infarction.
Dihydromyricetin confers cerebroprotection against subarachnoid hemorrhage via the Nrf2-dependent Prx2 signaling cascade.
Elucidating the pharmacological effects of Compound Kushen injection on MYC-P15-CCND1 signaling pathway in nasopharyngeal carcinoma - An in vitro study.
Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.
Identification and development of Tetra-ARMS PCR-based screening test for a genetic variant of OLA1 (Tyr254Cys) in the human failing heart.
Suppression of the gut microbiota-bile acid-FGF19 axis in patients with atrial fibrillation.
GPR37 promotes colorectal cancer liver metastases by enhancing the glycolysis and histone lactylation via Hippo pathway.
C-IGF1R encoded by cIGF1R acts as a molecular switch to restrict mitophagy of drug-tolerant persister tumour cells in non-small cell lung cancer.
Inhibition of ANXA2 activity attenuates epileptic susceptibility and GluA1 phosphorylation.
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
Mulberry leaf flavonoids activate BAT and induce browning of WAT to improve type 2 diabetes via regulating the AMPK/SIRT1/PGC-1α signaling pathway.
Co-delivery of azithromycin and ibuprofen by ROS-responsive polymer nanoparticles synergistically attenuates the acute lung injury.
FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation.
Lnc-PTCHD4-AS inhibits gastric cancer through MSH2-MSH6 dimerization and ATM-p53-p21 activation.
PDK4 rescues high-glucose-induced senescent fibroblasts and promotes diabetic wound healing through enhancing glycolysis and regulating YAP and JNK pathway.
PHD3 inhibits colon cancer cell metastasis through the occludin-p38 pathway.
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
Screening UFMylation-associated genes in heart tissues of Ufm1-transgenic mice.
Dopamine and cyclic adenosine monophosphate-regulated phosphoprotein with an apparent Mr of 32000 promotes colorectal cancer growth.
Lnc AC016727.1/BACH1/HIF-1 α signal loop promotes the progression of non-small cell lung cancer.
Activation of LXRα attenuates 2-Ethylhexyl diphenyl phosphate (EHDPP) induced placental dysfunction.
Sevoflurane induces neurotoxic effects on developing neurons through the WNK1/NKCC1/Ca(2+) /Drp-1 signalling pathway.
Discovery of a natural small-molecule AMP-activated kinase activator that alleviates nonalcoholic steatohepatitis.
PGC-1α Affects Epileptic Seizures by Regulating Mitochondrial Fusion in Epileptic Rats.
PDLIM3 supports hedgehog signaling in medulloblastoma by facilitating cilia formation.
GNB1 promotes hepatocellular carcinoma progression by targeting BAG2 to activate P38/MAPK signaling.
CB2R activation ameliorates late adolescent chronic alcohol exposure-induced anxiety-like behaviors during withdrawal by preventing morphological changes and suppressing NLRP3 inflammasome activation in prefrontal cortex microglia in mice.
BACH1 deficiency prevents neointima formation and maintains the differentiated phenotype of vascular smooth muscle cells by regulating chromatin accessibility.
IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma.
Estrogen-mediated oar-miR-485-5p targets PPP1R13B to regulate myoblast proliferation in sheep.
VPS35 promotes cell proliferation via EGFR recycling and enhances EGFR inhibitors response in gastric cancer.
Stabilization of nuclear β-catenin by inhibiting KDM2A mediates cerebral ischemic tolerance.
METTL3 promotes SMSCs chondrogenic differentiation by targeting the MMP3, MMP13, and GATA3.
IGF2 inhibits hippocampal over-activated microglia and alleviates depression-like behavior in LPS- treated male mice.
One Stone, Two Birds: A Peptide-Au(I) Infinite Coordination Supermolecule for the Confederate Physical and Biological Radiosensitization in Cancer Radiation Therapy.
Artesunate, a new antimalarial clinical drug, exhibits potent anti-AML activity by targeting the ROS/Bim and TFRC/Fe(2+) pathways.
Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage.
Key domains and residues of the receptor MRGPRX1 recognizing the peptide ligand BAM8-22.
LncRNA SPRY4-IT1 facilitates cell proliferation and angiogenesis of glioma via the miR-101-3p/EZH2/VEGFA signaling axis.
PKCθ Regulates Pituitary Adenoma Bone Invasion by Activating Osteoclast in NF-κB/IL-1β-Dependent Manner.
Deletion of Transglutaminase 2 from Mouse Astrocytes Significantly Improves Their Ability to Promote Neurite Outgrowth on an Inhibitory Matrix.
PDCD6 Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis through the AKT/GSK3β/β-catenin Pathway.
1,2,4,5-Tetrazine-tethered probes for fluorogenically imaging superoxide in live cells with ultrahigh specificity.
Mechanism Repositioning Based on Integrative Pharmacology: Anti-Inflammatory Effect of Safflower in Myocardial Ischemia-Reperfusion Injury.
Tibetan medicine Si-Wei-Qiang-Wei Powder ameliorates cholecystitis via inhibiting the production of pro-inflammatory cytokines and regulating the MAPK signaling pathway.
Decellularized brain extracellular matrix slice glioblastoma culture model recapitulates the interaction between cells and the extracellular matrix without a nutrient-oxygen gradient interference.
The tick saliva peptide HIDfsin2 promotes the tick-borne virus SFTSV replication in vitro by enhancing p38 signal pathway.
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.
Magnify is a universal molecular anchoring strategy for expansion microscopy.
Proteomics Profiling Reveals the Molecular Signatures and Potential Therapeutic Targets of Human Nasopharyngeal Carcinoma.
Chromatin remodeling and nucleoskeleton synergistically control osteogenic differentiation in different matrix stiffnesses.
Amyloid futures in the expanding pathology of brain aging and dementia.
Ginsenoside Rb1 improves energy metabolism after spinal cord injury.
Low rumen degradable starch promotes the growth performance of goats by increasing protein synthesis in skeletal muscle via the AMPK-mTOR pathway.
Docosahexaenoic Acid Alters Lipid Metabolism Processes via H3K9ac Epigenetic Modification in Dairy Goat.
MiR-145 regulates steroidogenesis in mouse primary granulosa cells by targeting Arpc5 and subsequent cytoskeleton remodeling.
Endothelial progenitor cell-derived exosomes promote anti-inflammatory macrophages via SOCS3/JAK2/STAT3 axis and improve the outcome of spinal cord injury.
DnaJC7 specifically regulates tau seeding.
Tumor-Associated Fibroblast-Derived Exosomal circDennd1b Promotes Pituitary Adenoma Progression by Modulating the miR-145-5p/ONECUT2 Axis and Activating the MAPK Pathway.
FBXO28 promotes proliferation, invasion, and metastasis of pancreatic cancer cells through regulation of SMARCC2 ubiquitination.
Scarless wound healing programmed by core-shell microneedles.
Hydrogen sulfide antagonizes formaldehyde-induced ferroptosis via preventing ferritinophagy by upregulation of GDF11 in HT22 cells.
ORP8 inhibits renal cell carcinoma progression by accelerating Stathmin1 degradation and microtubule polymerization.
Exosomes derived from oral squamous cell carcinoma tissue accelerate diabetic wound healing.
The distinct initiation sites and processing activities of TTLL4 and TTLL7 in glutamylation of brain tubulin.
MRPL51 is a downstream target of FOXM1 in promoting the malignant behaviors of lung adenocarcinoma.
Anisomycin inhibits Coxsackievirus B replication by promoting the lysosomal degradation of eEF1A1.
TANGO1 interacts with NRTN to promote hepatocellular carcinoma progression by regulating the PI3K/AKT/mTOR signaling pathway.
Neotuberostemonine and tuberostemonine ameliorate pulmonary fibrosis through suppressing TGF-β and SDF-1 secreted by macrophages and fibroblasts via the PI3K-dependent AKT and ERK pathways.
Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3-NFS1 axis in doxorubicin-induced cardiotoxicity.
Tumor necrosis factor-α reduces adiponectin production by decreasing transcriptional activity of peroxisome proliferator-activated receptor-γ in calf adipocytes.
Expression and Activity of the Transcription Factor CCAAT/Enhancer-Binding Protein β (C/EBPβ) Is Regulated by Specific Pulse-Modulated Radio Frequencies in Oligodendroglial Cells.
Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer.
αKG-driven RNA polymerase II transcription of cyclin D1 licenses malic enzyme 2 to promote cell-cycle progression.
Neobavaisoflavone induces pyroptosis of liver cancer cells via Tom20 sensing the activated ROS signal.
Transcriptional analysis of the expression and prognostic value of lipid droplet-localized proteins in hepatocellular carcinoma.
Triptolide with hepatotoxicity and nephrotoxicity used in local delivery treatment of myocardial infarction by thermosensitive hydrogel.
PPARα is involved in high-fat diet-induced risk avoidance impairment via the regulation of hippocampal BDNF.
Small intestine submucosa as a growth factor attractor promotes peripheral nerve regeneration by enhancing syndecan-3/glial cell line-derived neurotrophic factor (GDNF) signalling:in vivostudy().
Resveratrol-loaded macrophage exosomes alleviate multiple sclerosis through targeting microglia.
Dexmedetomidine attenuates airway inflammation and oxidative stress in asthma via the Nrf2 signaling pathway.
Inhibition of deubiquitinase USP28 attenuates cyst growth in autosomal dominant polycystic kidney disease.
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
Pine pollen extract alleviates ethanol-induced oxidative stress and apoptosis in HepG2 cells via MAPK signaling.
Zcf24, a zinc-finger transcription factor, is required for lactate catabolism and inhibits commensalism in Candida albicans.
Low-Dose Radiation Reduces Doxorubicin-Induced Myocardial Injury Through Mitochondrial Pathways.
Transcription factor ETS proto-oncogene 1 contributes to neuropathic pain by regulating histone deacetylase 1 in primary afferent neurons.
Exosomal-miR-129-2-3p derived from Fusobacterium nucleatum-infected intestinal epithelial cells promotes experimental colitis through regulating TIMELESS-mediated cellular senescence pathway.
Resveratrol Modulates the Redox Response and Bile Acid Metabolism to Maintain the Cholesterol Homeostasis in Fish Megalobrama amblycephala Offered a High-Carbohydrate Diet.
Network Pharmacology and Experimental Verification to Unveil the Mechanism of N-Methyl-D-Aspartic Acid Rescue Humantenirine-Induced Excitotoxicity.
Marine-Derived Natural Product HDYL-GQQ-495 Targets P62 to Inhibit Autophagy.
Jatrorrhizine Suppresses Murine-Norovirus-Triggered N-GSDMD-Dependent Pyroptosis in RAW264.7 Macrophages.
Anti-inflammatory and osteoprotective effects of Shi-Wei-Ru-Xiang pills on collagen-induced arthritis in rats via inhibiting MAPK and STAT3 pathways.
Polydopamine-Decorated PLCL Conduit to Induce Synergetic Effect of Electrical Stimulation and Topological Morphology for Peripheral Nerve Regeneration.
Zinc Promotes Spinal Cord Injury Recovery by Blocking the Activation of NLRP3 Inflammasome Through SIRT3-Mediated Autophagy.
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
3, 14, 19-Triacetyl Andrographolide alleviates the cognitive dysfunction of 3 × Tg-AD mice by inducing initiation and promoting degradation process of autophagy.
Mechanism of YY1 mediating autophagy dependent ferroptosis in PM2.5 induced cardiac fibrosis.
Collagen type Ⅰ-loaded methacrylamide hyaluronic acid hydrogel microneedles alleviate stress urinary incontinence in mice: A novel treatment and prevention strategy.
Bacterial infection promotes tumorigenesis of colorectal cancer via regulating CDC42 acetylation.
Mutation of the attractin gene impairs working memory in rats.
Revealing active components and action mechanism of Fritillariae Bulbus against non-small cell lung cancer through spectrum-effect relationship and proteomics.
TIPE2 deletion improves the therapeutic potential of adoptively transferred NK cells.
Baricitinib Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice by Inhibiting TGF-β1 Signaling Pathway.
Peroxiredoxin-6 Released by Astrocytes Contributes to Neuroapoptosis During Ischemia.
Site-specific phosphorylation of tau impacts mitochondrial biology and response to stressors.
SECTM1 is upregulated in immuno-hot tumors and predicts immunotherapeutic efficacy in multiple cancers.
Hyperactivation of TRPV4 causes the hippocampal pyroptosis pathway and results in cognitive impairment in LPS-treated mice.
Design, synthesis and biological evaluation of novel phenylfuran-bisamide derivatives as P-glycoprotein inhibitors against multidrug resistance in MCF-7/ADR cell.
microRNA-627-5p inhibits colorectal cancer cell proliferation, migration and invasion by targeting Wnt2.
A Novel Prenylflavonoid Icariside I Ameliorates Estrogen Deficiency-Induced Osteoporosis via Simultaneous Regulation of Osteoblast and Osteoclast Differentiation.
Si-Ni-SAN ameliorates obesity through AKT/AMPK/HSL pathway-mediated lipolysis: Network pharmacology and experimental validation.
UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.
Knockout of transient receptor potential ankyrin 1 (TRPA1) modulates the glial phenotype and alleviates perihematomal neuroinflammation after intracerebral hemorrhage in mice via MAPK/NF-κB signaling.
ADAMTS7-Mediated Complement Factor H Degradation Potentiates Complement Activation to Contributing to Renal Injuries.
TBC1 domain family member 25 protects against myocardial apoptosis and the proinflammatory response triggered by ischemia-reperfusion injury through suppression of the TAK1-JNK/p38 MAPK signaling cascade.
White adipose tissue-derived small extracellular vesicles: A new potential therapeutic reagent for accelerating diabetic wound healing.
Exogenous H(2) S promotes ubiquitin-mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S-sulfhydration.
Phenylbutyrate and Dichloroacetate Enhance the Liquid-Stored Boar Sperm Quality via PDK1 and PDK3.
Succinate-induced macrophage polarization and RBP4 secretion promote vascular sprouting in ocular neovascularization.
MRPL48 is a novel prognostic and predictive biomarker of hepatocellular carcinoma.
Piezo1 suppression reduces demyelination after intracerebral hemorrhage.
MicroRNA‑30a‑5p regulates cypermethrin-induced apoptosis of Sertoli cells by targeting KLF9 in vitro.
MicroRNA-144-3p protects against chemotherapy-induced apoptosis of ovarian granulosa cells and activation of primordial follicles by targeting MAP3K9.
CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway.
LncRNA SOCS2-AS1 promotes the progression of papillary thyroid cancer by destabilizing p53 protein.
TM6SF2 reduces lipid accumulation in vascular smooth muscle cells by inhibiting LOX-1 and CD36 expression.
Progressive Thinning of Retinal Nerve Fiber Layer/Ganglion Cell Layer (RNFL/GCL) as Biomarker and Pharmacological Target of Diabetic Retinopathy.
Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.
Apolipoprotein E Polymorphism Impacts White Matter Injury Through Microglial Phagocytosis After Experimental Subarachnoid Hemorrhage.
Systemic treatment with GnRH agonist produces antidepressant-like effects in LPS induced depression male mouse model.
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.
SIRT1 attenuates blood-spinal cord barrier disruption after spinal cord injury by deacetylating p66Shc.
In silico, in vitro and in vivo studies: Dibutyl phthalate promotes prostate cancer cell proliferation by activating Forkhead Box M1 and remission after Natura-α pretreatment.
Vagus nerve stimulation is a potential treatment for ischemic stroke.
Association between F-box-only protein 43 overexpression and hepatocellular carcinoma pathogenesis and prognosis.
Dual-specificity phosphatase 26-dificient neurons are susceptible to oxygen-glucose deprivation/reoxygenation-evoked apoptosis and proinflammatory response by affecting the TAK1-medaited JNK/P38 MAPK pathway.
The dichloromethane extract of Callicarpa longissima rich in diterpenoid phenols exerts anti-inflammatory effect via inhibiting the TLR4/NF-κB signaling pathway.
Enhanced E6AP-mediated ubiquitination of ENO1 via LINC00663 contributes to radiosensitivity of breast cancer by regulating mitochondrial homeostasis.
Novel Benzo Five-Membered Heterocycle Derivatives as P-Glycoprotein Inhibitors: Design, Synthesis, Molecular Docking, and Anti-Multidrug Resistance Activity.
Acinous cell AR42J-derived exosome miR125b-5p promotes acute pancreatitis exacerbation by inhibiting M2 macrophage polarization via PI3K/AKT signaling pathway.
Targeting Chondroitin Sulphate Synthase 1 (Chsy1) Promotes Axon Growth Following Neurorrhaphy by Suppressing Versican Accumulation.
A conditional knockout rat resource of mitochondrial protein-coding genes via a DdCBE-induced premature stop codon.
Effects of Spatial Expression of Activating Transcription Factor 4 on the Pathogenicity of Two Phenotypes of Bovine Viral Diarrhea Virus by Regulating the Endoplasmic Reticulum-Mediated Autophagy Process.
ME2 Promotes Hepatocellular Carcinoma Cell Migration through Pyruvate.
TET1-TRPV4 Signaling Contributes to Bone Cancer Pain in Rats.
Antidepressant-like effect of acute dose of Naringin involves suppression of NR1 and activation of protein kinase A/cyclic adenosine monophosphate response element-binding protein/brain-derived neurotrophic factor signaling in hippocampus.
The preventive and therapeutic effect of repetitive transcranial magnetic stimulation on radiation-induced brain injury in mice.
Selective Inhibition of Histone Deacetylase Class IIa With MC1568 Ameliorates Podocyte Injury.
Copy Number Analyses Identified a Novel Gene: APOBEC3A Related to Lipid Metabolism in the Pathogenesis of Preeclampsia.
Activation of Transcription Factor EB Is Associated With Adipose Tissue Lipolysis in Dairy Cows With Subclinical Ketosis.
The Hair Growth-Promoting Effect of Gardenia florida Fruit Extract and Its Molecular Regulation.
Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK.
Epoxyeicosatrienoic Acids Inhibit the Activation of Murine Fibroblasts by Blocking the TGF-β1-Smad2/3 Signaling in a PPARγ-Dependent Manner.
Identifying Potential Tumor Antigens and Antigens-Related Subtypes in Hepatocellular Carcinoma for mRNA Vaccine Development.
Dexpramipexole Attenuates White Matter Injury to Facilitate Locomotion and Motor Coordination Recovery via Reducing Ferroptosis after Intracerebral Hemorrhage.
Extracellular CIRP Upregulates Proinflammatory Cytokine Expression via the NF-kappaB and ERK1/2 Signaling Pathways in Psoriatic Keratinocytes.
Metformin Protects against Spinal Cord Injury and Cell Pyroptosis via AMPK/NLRP3 Inflammasome Pathway.
Prediction of Prognosis and Recurrence of Bladder Cancer by ECM-Related Genes.
Hyperhomocysteinemia Promotes Cardiac Hypertrophy in Hypertension.
Repeated Yueju, But Not Fluoxetine, Induced Sustained Antidepressant Activity in a Mouse Model of Chronic Learned Helplessness: Involvement of CaMKII Signaling in the Hippocampus.
Silencing lncRNA 93358 Inhibits the Apoptosis of Myocardial Cells in Myocardial Infarction Rats by Inducing the Expression of SLC8A1.
MiR-3571 modulates the proliferation and migration of vascular smooth muscle cells by targeting claudin 1.
Caspase-1-mediated extracellular vesicles derived from pyroptotic alveolar macrophages promote inflammation in acute lung injury.
Diprotin A TFA Exerts Neurovascular Protection in Ischemic Cerebral Stroke.
Inhibiting Sphingosine 1-Phosphate Receptor Subtype 3 Attenuates Brain Damage During Ischemia-Reperfusion Injury by Regulating nNOS/NO and Oxidative Stress.
BRD7 Stabilizes P53 via Dephosphorylation of MDM2 to Inhibit Tumor Growth in Breast Cancer Harboring Wild-type P53.
Qing-Re-Xiao-Zheng-Yi-Qi formula relieves kidney damage and activates mitophagy in diabetic kidney disease.
Therapeutic effects of shaogan fuzi decoction in rheumatoid arthritis: Network pharmacology and experimental validation.
Cuproptosis status affects treatment options about immunotherapy and targeted therapy for patients with kidney renal clear cell carcinoma.
Optical Visualization of Red-GQDs' Organelles Distribution and Localization in Living Cells.
ANXA1: An Important Independent Prognostic Factor and Molecular Target in Glioma.
Oar-miR-432 Regulates Fat Differentiation and Promotes the Expression of BMP2 in Ovine Preadipocytes.
Sperm Autoantigenic Protein 17 Predicts the Prognosis and the Immunotherapy Response of Cancers: A Pan-Cancer Analysis.
Sleeve Gastrectomy-Induced AMPK Activation Attenuates Diabetic Cardiomyopathy by Maintaining Mitochondrial Homeostasis via NR4A1 Suppression in Rats.
S1PR3, as a Core Protein Related to Ischemic Stroke, is Involved in the Regulation of Blood-Brain Barrier Damage.
Punicalagin Alleviates Psoriasis by Inhibiting NF-κB-Mediated IL-1β Transcription and Caspase-1-Regulated IL-1β Secretion.
Avasimibe Alleviates Disruption of the Airway Epithelial Barrier by Suppressing the Wnt/β-Catenin Signaling Pathway.
Identification of super-enhancer-driven peptidyl arginine deiminases as potential biomarkers and therapeutic targets for osimertinib-resistant non-small cell lung cancer.
Small RNA perspective of physical exercise-related improvement of male reproductive dysfunction due to obesity.
Berberine prevents lethal EV71 neurological infection in newborn mice.
X-box binding protein 1: A new metabolic mediator and drug target of metformin?
Prrx1 promotes resistance to temozolomide by upregulating ABCC1 and inducing vasculogenic mimicry in glioma.
Interleukin 33-mediated inhibition of A-type K(+) channels induces sensory neuronal hyperexcitability and nociceptive behaviors in mice.
The PROTAC selectively degrading Bcl-x(L) represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while sparing bone growth.
A novel HCC prognosis predictor PDSS1 affects the cell cycle through the STAT3 signaling pathway in HCC.
The Synergistic Cytotoxic Effects of GW5074 and Sorafenib by Impacting Mitochondrial Functions in Human Colorectal Cancer Cell Lines.
Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6.
AQP5 Is a Novel Prognostic Biomarker in Pancreatic Adenocarcinoma.
Transient Receptor Potential Cation Channel Subfamily V Member 1 Expression Promotes Chemoresistance in Non-Small-Cell Lung Cancer.
Label-free LC-MS/MS proteomics analyses reveal CLIC1 as a predictive biomarker for bladder cancer staging and prognosis.
HIF-1/2α-Activated RNF146 Enhances the Proliferation and Glycolysis of Hepatocellular Carcinoma Cells via the PTEN/AKT/mTOR Pathway.
Chicken ISG12(2) attenuates Newcastle disease virus and enhances the efficiency of Newcastle disease vaccine via activating immune pathways.
Nav1.8 in keratinocytes contributes to ROS-mediated inflammation in inflammatory skin diseases.
Silica nanoparticle exposure inhibits surfactant protein A and B in A549 cells through ROS-mediated JNK/c-Jun signaling pathway.
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Vagus nerve stimulation promotes the M1-to-M2 transition via inhibition of TLR4/NF-κB in microglial to rescue the reperfusion injury.
UFL1 alleviates ER stress and apoptosis stimulated by LPS via blocking the ferroptosis pathway in human granulosa-like cells.
Elevated phosphorylation of EGFR in NSCLC due to mutations in PTPRH.
Deficiency of proline/serine-rich coiled-coil protein 1 (PSRC1) accelerates trimethylamine N-oxide-induced atherosclerosis in ApoE(-/-) mice.
Phosphorylation of Ser82 on IRF3 acts as negative-feedback regulation of IRF3-dependent innate immunity.
Gut microbiota-derived metabolites contribute negatively to hindgut barrier function development at the early weaning goat model.
Metabolic Syndrome Ameliorated by 4-Methylesculetin by Reducing Hepatic Lipid Accumulation.
Proteomic and Biochemical Approaches Elucidate the Role of Millimeter-Wave Irradiation in Wheat Growth under Flooding Stress.
Acid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis.
Supramolecular Hydrogel-Wrapped Gingival Mesenchymal Stem Cells in Cutaneous Radiation Injury.
Proteomic characterization of gastric cancer response to chemotherapy and targeted therapy reveals new therapeutic strategies.
Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model.
Role of PARP-1 in Human Cytomegalovirus Infection and Functional Partners Encoded by This Virus.
MARCH1 promotes the growth and maintaining of stem cell-like characteristics of gastric cancer cells by activating the Wnt/β-catenin signaling pathway.
LncRNA ALKBH3-AS1 enhances ALKBH3 mRNA stability to promote hepatocellular carcinoma cell proliferation and invasion.
Proteome-wide analysis of the hippocampus in adolescent male mice with learning and memory impairment caused by chronic ethanol exposure.
The phytochemical constituents and protective effect of Fritillaria hupehensis on acute lung injury.
Reticulocalbin3: A Ca(2+) homeostasis regulator that promotes esophageal squamous cell carcinoma progression and cisplatin resistance.
Targeting PERK mediated endoplasmic reticulum stress attenuates neuroinflammation and alleviates lipopolysaccharide-induced depressive-like behavior in male mice.
Local Application of Krill Oil Accelerates the Healing of Artificially Created Wounds in Diabetic Mice.
Hepatic inactivation of murine Surf4 results in marked reduction in plasma cholesterol.
Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood-Milk Barrier.
Knockdown of CLAUDIN-6 Inhibited Apoptosis and Induced Proliferation of Bovine Cumulus Cells.
Hypoxia-Regulated lncRNA USP2-AS1 Drives Head and Neck Squamous Cell Carcinoma Progression.
Angiotensin-converting enzyme 2 identifies immuno-hot tumors suggesting angiotensin-(1-7) as a sensitizer for chemotherapy and immunotherapy in breast cancer.
Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis.
TRPM8 contributes to sex dimorphism by promoting recovery of normal sensitivity in a mouse model of chronic migraine.
The role of E3 ubiquitin ligase WWP2 and the regulation of PARP1 by ubiquitinated degradation in acute lymphoblastic leukemia.
Kaempferol prevents angiogenesis of rat intestinal microvascular endothelial cells induced by LPS and TNF-α via inhibiting VEGF/Akt/p38 signaling pathways and maintaining gut-vascular barrier integrity.
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
Synthetic Retinoid Kills Drug-Resistant Cancer Stem Cells via Inducing RARγ-Translocation-Mediated Tension Reduction and Chromatin Decondensation.
Knockdown of TTC9 inhibits the proliferation, migration and invasion, but induces the apoptosis of lung adenocarcinoma cells.
Overexpression of PYGO1 promotes early cardiac lineage development in human umbilical cord mesenchymal stromal/stem cells by activating the Wnt/β-catenin pathway.
Homozygous missense mutation in CCDC155 disrupts the transmembrane distribution of CCDC155 and SUN1, resulting in non-obstructive azoospermia and premature ovarian insufficiency in humans.
Hydrogen improves exercise endurance in rats by promoting mitochondrial biogenesis.
Hyperglycemia promotes myocardial dysfunction via the ERS-MAPK10 signaling pathway in db/db mice.
Regulation of cohesin-mediated chromosome folding by PDS5 in mammals.
Discovery of a novel Pleuromutilin derivative as anti-IPF lead compound via high-throughput assay.
Functional Attenuation of UCP1 as the Potential Mechanism for a Thickened Blubber Layer in Cetaceans.
Trichostatin D as a Novel KLF2 Activator Attenuates TNFα-Induced Endothelial Inflammation.
Differential requirements of IQUB for the assembly of radial spoke 1 and the motility of mouse cilia and flagella.
Hydrogen Sulfide Regulates SERCA2a Ubiquitylation via Muscle RING Finger-1 S-Sulfhydration to Affect Cardiac Contractility in db/db Mice.
mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters.
NAP1L5 targeting combined with MYH9 Inhibit HCC progression through PI3K/AKT/mTOR signaling pathway.
Inhibitory effect of tanshinone IIA, resveratrol and silibinin on enterovirus 68 production through inhibiting ATM and DNA-PK pathway.
cGAS-STING mediates cytoplasmic mitochondrial-DNA-induced inflammatory signal transduction during accelerated senescence of pancreatic β-cells induced by metabolic stress.
SMAD4 Inhibits Granulosa Cell Apoptosis via the miR-183-96-182 Cluster and FoxO1 Axis.
Type IIB PKA is highly expressed in β cells and controls cell proliferation via regulating Cyclin D1 expression.
The roles of grouper TAK1 in regulating the infection of Singapore grouper iridovirus.
Ubiquitin-like modifier 1 ligating enzyme 1 relieves cisplatin-induced premature ovarian failure by reducing endoplasmic reticulum stress in granulosa cells.
MiR-135a-5p suppresses trophoblast proliferative, migratory, invasive, and angiogenic activity in the context of unexplained spontaneous abortion.
Aberrant translation regulated by METTL1/WDR4-mediated tRNA N7-methylguanosine modification drives head and neck squamous cell carcinoma progression.
Ubiquitylation of cyclin C by HACE1 regulates cisplatin-associated sensitivity in gastric cancer.
Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury.
p62 Promotes the Mitochondrial Localization of p53 through Its UBA Domain and Participates in Regulating the Sensitivity of Ovarian Cancer Cells to Cisplatin.
Iron metabolism protein transferrin receptor 1 involves in cervical cancer progression by affecting gene expression and alternative splicing in HeLa cells.
Effects of ALA-PDT on the macrophages in wound healing and its related mechanisms in vivo and in vitro.
Rutin-activated adipose tissue thermogenesis is correlated with increased intestinal short-chain fatty acid levels.
Dexmedetomidine attenuates perioperative neurocognitive disorders by suppressing hippocampal neuroinflammation and HMGB1/RAGE/NF-κB signaling pathway.
NPM1 promotes cell proliferation by targeting PRDX6 in colorectal cancer.
Deacetylation of Caveolin-1 by Sirt6 induces autophagy and retards high glucose-stimulated LDL transcytosis and atherosclerosis formation.
Heart-targeted amelioration of sepsis-induced myocardial dysfunction by microenvironment responsive nitric oxide nanogenerators in situ.
Sesamin Activates Skeletal Muscle FNDC5 Expression and Increases Irisin Secretion via the SIRT1 Signaling Pathway.
The mechanism of dioscin preventing lung cancer based on network pharmacology and experimental validation.
circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop.
Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached.
Transcriptome study digs out BMP2 involved in adipogenesis in sheep tails.
JNK and Jag1/Notch2 co-regulate CXCL16 to facilitate cypermethrin-induced kidney damage.
Difenoconazole causes spleen tissue damage and immune dysfunction of carp through oxidative stress and apoptosis.
Chronic exposure of alcohol triggers microglia-mediated synaptic elimination inducing cognitive impairment.
Lysyl oxidase-like 2 inhibitor rescues D-galactose-induced skeletal muscle fibrosis.
The neuroprotective effects of GPR55 against hippocampal neuroinflammation and impaired adult neurogenesis in CSDS mice.
Time series RNA-seq analysis identifies MAPK10 as a critical gene in diabetes mellitus-induced atrial fibrillation in mice.
Cortistatin attenuates titanium particle-induced osteolysis through regulation of TNFR1-ROS-caspase-3 signaling in osteoblasts.
Morphological and Proteomic Analyses of Soybean Seedling Interaction Mechanism Affected by Fiber Crosslinked with Zinc-Oxide Nanoparticles.
Discovery of Novel Phosphoinositide-3-Kinase α Inhibitors with High Selectivity, Excellent Bioavailability, and Long-Acting Efficacy for Gastric Cancer.
Dysregulation of SIRT3 SUMOylation Confers AML Chemoresistance via Controlling HES1-Dependent Fatty Acid Oxidation.
Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage.
Quantitative proteomics analysis to assess protein expression levels in the ovaries of pubescent goats.
Increased m6A-RNA methylation and FTO suppression is associated with myocardial inflammation and dysfunction during endotoxemia in mice.
BCAA-BCKA axis regulates WAT browning through acetylation of PRDM16.
Bioglass promotes wound healing by inhibiting endothelial cell pyroptosis through regulation of the connexin 43/reactive oxygen species (ROS) signaling pathway.
A homozygous loss-of-function mutation in FBXO43 causes human non-obstructive azoospermia.
CHMFL-BMX-078, a BMX inhibitor, overcomes the resistance of melanoma to vemurafenib via inhibiting AKT pathway.
An efficient strategy for digging protein-protein interactions for rational drug design - A case study with HIF-1α/VHL.
Qingwei San treats oral ulcer subjected to stomach heat syndrome in db/db mice by targeting TLR4/MyD88/NF-κB pathway.
ID2 inhibits innate antiviral immunity by blocking TBK1- and IKKε-induced activation of IRF3.
Increased expression of osteopontin in subchondral bone promotes bone turnover and remodeling, and accelerates the progression of OA in a mouse model.
The bibenzyl derivatives of Dendrobium officinale prevent UV-B irradiation induced photoaging via SIRT3.
Sodium hydrosulfide reverses β(2)-microglobulin-induced depressive-like behaviors of male Sprague-Dawley rats: Involving improvement of synaptic plasticity and enhancement of Warburg effect in hippocampus.
Nrf2 loss of function exacerbates endoplasmic reticulum stress-induced apoptosis in TBI mice.
Krill Oil Inhibits NLRP3 Inflammasome Activation in the Prevention of the Pathological Injuries of Diabetic Cardiomyopathy.
Amelioration of scopolamine-induced learning and memory impairment by the TRPV4 inhibitor HC067047 in ICR mice.
DsbA-L interacts with VDAC1 in mitochondrion-mediated tubular cell apoptosis and contributes to the progression of acute kidney disease.
Supervillin Contributes to LPS-induced Inflammatory Response in THP-1 Cell-derived Macrophages.
Chronic exposure to biomass ambient particulate matter triggers alveolar macrophage polarization and activation in the rat lung.
Dual effects of bisphenol A on wound healing, involvement of estrogen receptor β.
KDM2B overexpression prevents myocardial ischemia-reperfusion injury in rats through regulating inflammatory response via the TLR4/NF-κB p65 axis.
MxB inhibits long interspersed element type 1 retrotransposition.
Resveratrol attenuates inflammation and apoptosis through alleviating endoplasmic reticulum stress via Akt/mTOR pathway in fungus-induced allergic airways inflammation.
Vagus nerve stimulation alleviated cerebral ischemia and reperfusion injury in rats by inhibiting pyroptosis via α7 nicotinic acetylcholine receptor.
Toddalolactone protects against osteoarthritis by ameliorating chondrocyte inflammation and suppressing osteoclastogenesis.
RFC2: a prognosis biomarker correlated with the immune signature in diffuse lower-grade gliomas.
The expression of m6A enzymes in the hippocampus of diabetic cognitive impairment mice and the possible improvement of YTHDF1.
Inhibition of base editors with anti-deaminases derived from viruses.
FAEE exerts a protective effect against osteoporosis by regulating the MAPK signalling pathway.
Cdk5 Promotes Mitochondrial Fission via Drp1 Phosphorylation at S616 in Chronic Ethanol Exposure-Induced Cognitive Impairment.
Cellular communication network factor 1 interlinks autophagy and ERK signaling to promote osteogenesis of periodontal ligament stem cells.
The protective effects of Xuebijing injection on intestinal injuries of mice exposed to irradiation.
Defective autophagy triggered by arterial cyclic stretch promotes neointimal hyperplasia in vein grafts via the p62/nrf2/slc7a11 signaling pathway.
Attachment of -tBu groups to aza-BODIPY core at 3,5-sites with ultra-large Stokes shift to enhance photothermal therapy through apoptosis mechanism.
PVT1/miR-145-5p/HK2 modulates vascular smooth muscle cells phenotype switch via glycolysis: The new perspective on the spiral artery remodeling.
mmu-lncRNA 121686/hsa-lncRNA 520657 induced by METTL3 drive the progression of AKI by targeting miR-328-5p/HtrA3 signaling axis.
Proteomic-Based Approach Reveals the Involvement of Apolipoprotein A-I in Related Phenotypes of Autism Spectrum Disorder in the BTBR Mouse Model.
RNA-m6A modification of HDGF mediated by Mettl3 aggravates the progression of atherosclerosis by regulating macrophages polarization via energy metabolism reprogramming.
Effect of miR-143-3p from Extracellular Vesicles of Porcine Uterine Luminal Fluid on Porcine Trophoblast Cells.
Melatonin protects oocytes from cadmium exposure-induced meiosis defects by changing epigenetic modification and enhancing mitochondrial morphology in the mouse.
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
A synthetic pregnenolone analog promotes microtubule dynamics and neural development.
Hypoxia facilitates proliferation of smooth muscle cells derived from pluripotent stem cells for vascular tissue engineering.
ROS-responsive polymer nanoparticles with enhanced loading of dexamethasone effectively modulate the lung injury microenvironment.
Cypermethrin inhibits proliferation of Sertoli cells through AR involving DAB2IP/PI3K/AKT signaling pathway in vitro.
Effect of Silkworm Pupa Protein Hydrolysates on Proliferation of Gastric Cancer Cells In Vitro.
The Exocyst Is Required for CD36 Fatty Acid Translocase Trafficking and Free Fatty Acid Uptake in Skeletal Muscle Cells.
Chemical profile and miscarriage prevention evaluation of Jiao-Ai Decoction, a classical traditional Chinese formula.
Inhibition of BET Family Proteins Suppresses African Swine Fever Virus Infection.
The mechanism on Prevotella melaninogenica promoting the inflammatory progression of oral lichen planus.
Aperture Modulation of Isoreticular Metal Organic Frameworks for Targeted Antitumor Drug Delivery.
Quantitative proteomics and functional analysis identified novel targets for missed abortion.
Apextrin from Ruditapes philippinarum functions as pattern recognition receptor and modulates NF-κB pathway.
Cognitive enhancement and neuroprotective effects of OABL, a sesquiterpene lactone in 5xFAD Alzheimer's disease mice model.
O-GlcNAc transferase promotes the nuclear localization of the focal adhesion-associated protein Zyxin to regulate UV-induced cell death.
Protective Effects of Scutellarin on Acute Alcohol Intestinal Injury.
The lncRNA MIAT regulates CPT-1a mediated cardiac hypertrophy through m(6)A RNA methylation reading protein Ythdf2.
IL-37 isoform D acts as an inhibitor of soluble ST2 to boost type 2 immune homeostasis in white adipose tissue.
Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue.
The Tobacco β-Cembrenediol: A Prostate Cancer Recurrence Suppressor Lead and Prospective Scaffold via Modulation of Indoleamine 2,3-Dioxygenase and Tryptophan Dioxygenase.
The plant hormone abscisic acid stimulates megakaryocyte differentiation from human iPSCs in vitro.
Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.
ORP5 promotes tumor metastasis via stabilizing c-Met in renal cell carcinoma.
Age-related visual impairments and retinal ganglion cells axonal degeneration in a mouse model harboring OPTN (E50K) mutation.
Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma.
Bioinformatic Approach to Unveil Key Differentially Expressed Proteins in Human Sperm After Slow and Rapid Cryopreservation.
The Regulatory Role of GBF1 on Osteoclast Activation Through EIF2a Mediated ER Stress and Novel Marker FAM129A Induction.
Tributyltin Oxide Exposure During in vitro Maturation Disrupts Oocyte Maturation and Subsequent Embryonic Developmental Competence in Pigs.
Iron Overload-Induced Ferroptosis Impairs Porcine Oocyte Maturation and Subsequent Embryonic Developmental Competence in vitro.
The m(6)A Reader YTHDF1 Facilitates the Tumorigenesis and Metastasis of Gastric Cancer via USP14 Translation in an m(6)A-Dependent Manner.
Mechanically Activated Calcium Channel PIEZO1 Modulates Radiation-Induced Epithelial-Mesenchymal Transition by Forming a Positive Feedback With TGF-β1.
Expression and Functional Analysis of lncRNAs Involved in Platelet-Derived Growth Factor-BB-Induced Proliferation of Human Aortic Smooth Muscle Cells.
Transcriptome Differences in Pig Tracheal Epithelial Cells in Response to Pasteurella Multocida Infection.
DCI after Aneurysmal Subarachnoid Hemorrhage Is Related to the Expression of MFG-E8.
USP37 downregulation elevates the Chemical Sensitivity of Human Breast Cancer Cells to Adriamycin.
MnSOD Lysine 68 acetylation leads to cisplatin and doxorubicin resistance due to aberrant mitochondrial metabolism.
Rosuvastatin Nanomicelles Target Neuroinflammation and Improve Neurological Deficit in a Mouse Model of Intracerebral Hemorrhage.
GluN2A/ERK/CREB Signaling Pathway Involved in Electroacupuncture Regulating Hypothalamic-Pituitary-Adrenal Axis Hyperactivity.
Latent Sex Differences in CaMKII-nNOS Signaling That Underlie Antidepressant-Like Effects of Yueju-Ganmaidazao Decoction in the Hippocampus.
PADI6 Regulates Trophoblast Cell Migration-Invasion Through the Hippo/YAP1 Pathway in Hydatidiform Moles.
RNF128 suppresses the malignancy of colorectal cancer cells via inhibition of Wnt/β-catenin signaling.
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Ilexsaponin A(1) Ameliorates Diet-Induced Nonalcoholic Fatty Liver Disease by Regulating Bile Acid Metabolism in Mice.
Loss of Diacylglycerol Kinase α Enhances Macrophage Responsiveness.
ZnT8 Deficiency Protects From APAP-Induced Acute Liver Injury by Reducing Oxidative Stress Through Upregulating Hepatic Zinc and Metallothioneins.
The Downregulation of eIF3a Contributes to Vemurafenib Resistance in Melanoma by Activating ERK via PPP2R1B.
CXCL5 Downregulation in Villous Tissue Is Correlated With Recurrent Spontaneous Abortion.
Protective Effect of Remdesivir Against Pulmonary Fibrosis in Mice.
Chlorogenic Acid Ameliorates Damage Induced by Fluorene-9-Bisphenol in Porcine Sertoli Cells.
Glycosylation of Siglec15 promotes immunoescape and tumor growth.
Human umbilical cord-derived mesenchymal stem cell therapy ameliorates lupus through increasing CD4+ T cell senescence via MiR-199a-5p/Sirt1/p53 axis.
circCDYL2, Overexpressed in Highly Migratory Colorectal Cancer Cells, Promotes Migration by Binding to Ezrin.
The Role of KDM2B and EZH2 in Regulating the Stemness in Colorectal Cancer Through the PI3K/AKT Pathway.
Expression and prognostic potential of PLEK2 in head and neck squamous cell carcinoma based on bioinformatics analysis.
Therapy of spinal cord injury by zinc modified gold nanoclusters via immune-suppressing strategies.
TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity.
Protocol for nuclear export signal characterization of cGAS in mammalian cells.
Yixin-Fumai granules improve sick sinus syndrome in aging mice through Nrf-2/HO-1 pathway: A new target for sick sinus syndrome.
MicroRNA‑8063 targets heterogeneous nuclear ribonucleoprotein AB to inhibit the self‑renewal of colorectal cancer stem cells via the Wnt/β‑catenin pathway.
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Cucurbit[7]uril as a Broad-Spectrum Antiviral Agent against Diverse RNA Viruses.
ZBP1-MLKL necroptotic signaling potentiates radiation-induced antitumor immunity via intratumoral STING pathway activation.
NORHA, a novel follicular atresia-related lncRNA, promotes porcine granulosa cell apoptosis via the miR-183-96-182 cluster and FoxO1 axis.
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Frugoside delays osteoarthritis progression via inhibiting miR-155-modulated synovial macrophage M1 polarization.
Naringin Promotes Skeletal Muscle Fiber Remodeling by the AdipoR1-APPL1-AMPK Signaling Pathway.
Comparative Proteomics of Rat Olfactory Bulb Reveal Insights into Susceptibility and Resiliency to Chronic-stress-induced Depression or Anxiety.
Arsenic trioxide induces expression of BCL-2 expression via NF-κB and p38 MAPK signaling pathways in BEAS-2B cells during apoptosis.
Reduced activity of intestinal surface Na(+)/H(+) exchanger NHE3 is a key factor for induction of diarrhea after PEDV infection in neonatal piglets.
Tripartite motif-containing protein 16 protects against myocardial ischemia/reperfusion injury by affecting the Keap1/Nrf2 axis.
EGFR and ERK activation resists flavonoid quercetin-induced anticancer activities in human cervical cancer cells in vitro.
Guaiazulene derivative 1,2,3,4-tetrahydroazuleno[1,2-b] tropone reduces the production of ATP by inhibiting electron transfer complex II.
Vagus nerve stimulation mediates microglia M1/2 polarization via inhibition of TLR4 pathway after ischemic stroke.
A network pharmacology approach to reveal the pharmacological targets and biological mechanism of compound kushen injection for treating pancreatic cancer based on WGCNA and in vitro experiment validation.
Inhibition of the NLRP3 inflammasome with MCC950 prevents chronic social isolation-induced depression-like behavior in male mice.
1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-κB/MAPK pathways.
Iptakalim alleviates synaptic damages via targeting mitochondrial ATP-sensitive potassium channel in depression.
Characterization of ALTO-encoding circular RNAs expressed by Merkel cell polyomavirus and trichodysplasia spinulosa polyomavirus.
Extracellular vesicles-based pre-targeting strategy enables multi-modal imaging of orthotopic colon cancer and image-guided surgery.
Functional domains and amino acid residues of Japanese eel IRF1, AjIRF1, regulate its nuclear import and IFN/Mx promoter activation.
Inhibition of ERAD synergizes with FTS to eradicate pancreatic cancer cells.
The combination of G-CSF and AMD3100 mobilizes bone marrow-derived stem cells to protect against cisplatin-induced acute kidney injury in mice.
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
lncRNA Ttc3-209 Promotes the Apoptosis of Retinal Ganglion Cells in Retinal Ischemia Reperfusion Injury by Targeting the miR-484/Wnt8a Axis.
Sesamin induces cell cycle arrest and apoptosis through p38/C-Jun N-terminal kinase mitogen-activated protein kinase pathways in human colorectal cancer cells.
Pharmacological effects of indole alkaloids from Alstonia scholaris (L.) R. Br. on pulmonary fibrosis in vivo.
Glycine alleviates fluoride-induced oxidative stress, apoptosis and senescence in a porcine testicular Sertoli cell line.
Alternative splicing transitions associate with emerging atrophy phenotype during denervation-induced skeletal muscle atrophy.
Melatonin ameliorates cypermethrin-induced impairments by regulating oxidative stress, DNA damage and apoptosis in porcine Sertoli cells.
Resolving the graft ischemia-reperfusion injury during liver transplantation at the single cell resolution.
Ameliorative effects of eosinophil deficiency on immune response, endoplasmic reticulum stress, apoptosis, and autophagy in fungus-induced allergic lung inflammation.
Expression of deubiquitinases in human gingiva and cultured human gingival fibroblasts.
Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
PI3K/AKT pathway mediates the antidepressant- and anxiolytic-like roles of hydrogen sulfide in streptozotocin-induced diabetic rats via promoting hippocampal neurogenesis.
AEG-1 Knockdown Sensitizes Glioma Cells to Radiation Through Impairing Homologous Recombination Via Targeting RFC5.
The role of SAMM50 in non-alcoholic fatty liver disease: from genetics to mechanisms.
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking.
Theaflavin Promotes Mitochondrial Abundance and Glucose Absorption in Myotubes by Activating the CaMKK2-AMPK Signal Axis via Calcium-Ion Influx.
Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model.
Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB.
Attractin Gene Deficiency in Rats Leads to Impairments in Both Activity and Spatial Learning and Memory.
Betulinic acid attenuated bleomycin-induced pulmonary fibrosis by effectively intervening Wnt/β-catenin signaling.
ETV5 Regulates Hepatic Fatty Acid Metabolism Through PPAR Signaling Pathway.
Identification and Bioinformatic Assessment of circRNA Expression After RMI1 Knockdown and Ionizing Radiation Exposure.
NADPH levels affect cellular epigenetic state by inhibiting HDAC3-Ncor complex.
Libertellenone H, a Natural Pimarane Diterpenoid, Inhibits Thioredoxin System and Induces ROS-Mediated Apoptosis in Human Pancreatic Cancer Cells.
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.
A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA.
Formaldehyde induces ferroptosis in hippocampal neuronal cells by upregulation of the Warburg effect.
CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson's disease.
PDGF/MEK/ERK axis represses Ca(2+) clearance via decreasing the abundance of plasma membrane Ca(2+) pump PMCA4 in pulmonary arterial smooth muscle cells.
BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.
Oral Administration of Probiotic Bifidobacterium breve Improves Facilitation of Hippocampal Memory Extinction via Restoration of Aberrant Higher Induction of Neuropsin in an MPTP-Induced Mouse Model of Parkinson's Disease.
A novel tonicity-responsive microRNA miR-23a-5p modulates renal cell survival under osmotic stress through targeting heat shock protein 70 HSPA1B.
Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology.
Hypoxia-inducible factor-1α promotes proliferation of airway smooth muscle cells through miRNA-103-mediated signaling pathway under hypoxia.
Integrated Metabolomics and Transcriptomics Analyses Reveal Metabolic Landscape in Neuronal Cells during JEV Infection.
Decreased NHE3 activity in intestinal epithelial cells in TGEV and PEDV-induced piglet diarrhea.
The STING antagonist H-151 ameliorates psoriasis via suppression of STING/NF-κB-mediated inflammation.
Mbd2 deficiency alleviates retinal cell apoptosisvia the miR-345-5p/Atf1 axis in high glucoseinjury and streptozotocin-induced diabetic mice.
HRD1-mediated METTL14 degradation regulates m(6)A mRNA modification to suppress ER proteotoxic liver disease.
TRPV4 inhibitor HC067047 produces antidepressant-like effect in LPS-induced depression mouse model.
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
NOD2 deficiency confers a pro-tumorigenic macrophage phenotype to promote lung adenocarcinoma progression.
Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Ameliorate HaCaT Cell Photo-Aging.
Isoeucommin A attenuates kidney injury in diabetic nephropathy through the Nrf2/HO-1 pathway.
Cypermethrin induces Sertoli cell apoptosis through mitochondrial pathway associated with calcium.
TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.
The E2F1/USP11 positive feedback loop promotes hepatocellular carcinoma metastasis and inhibits autophagy by activating ERK/mTOR pathway.
High-Carbohydrate Diet Alleviates the Oxidative Stress, Inflammation and Apoptosis of Megalobrama amblycephala Following Dietary Exposure to Silver Nanoparticles.
Triptolide impairs glycolysis by suppressing GATA4/Sp1/PFKP signaling axis in mouse Sertoli cells.
KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathway.
HSP/HSC70 activity is required for Bombyx mori nucleopolyhedrovirus replication at the early infectious phase.
Salidroside Attenuates Doxorubicin-Induced Cardiac Dysfunction Partially Through Activation of QKI/FoxO1 Pathway.
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1.
Neural Tube Defects and ZIC4 Hypomethylation in Relation to Polycyclic Aromatic Hydrocarbon Exposure.
Identification of Transcriptional Variation in Aortic Remodeling Using a Murine Transverse Aortic Constriction (TAC) Model.
Similar Repair Effects of Human Placenta, Bone Marrow Mesenchymal Stem Cells, and Their Exosomes for Damaged SVOG Ovarian Granulosa Cells.
Beneficial Effects of Crocin against Depression via Pituitary Adenylate Cyclase-Activating Polypeptide.
Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway.
Skp2 modulates proliferation, senescence and tumorigenesis of glioma.
HCK can serve as novel prognostic biomarker and therapeutic target for Breast Cancer patients.
Repression of FGF signaling is responsible for Dnmt3b inhibition and impaired de novo DNA methylation during early development of in vitro fertilized embryos.
G Protein-Coupled Receptor 109A Maintains the Intestinal Integrity and Protects Against ETEC Mucosal Infection by Promoting IgA Secretion.
Integration of Transcriptomics and Metabolomics Reveals the Antitumor Mechanism Underlying Shikonin in Colon Cancer.
Possible Roles of Proinflammatory Signaling in Keratinocytes Through Aryl Hydrocarbon Receptor Ligands for the Development of Squamous Cell Carcinoma.
Cyclophilin A plays an important role in embryo implantation through activating Stat3.
Control the fate of human umbilical cord mesenchymal stem cells with dual-enzymatically cross-linked gelatin hydrogels for potential applications in nerve regeneration.
miR-361-5p Mediates SMAD4 to Promote Porcine Granulosa Cell Apoptosis through VEGFA.
Neddylation promotes protein translocation between the cytoplasm and nucleus.
EPS8 regulates an NLRP3 inflammasome-independent caspase-1 activation pathway in monosodium urate crystal-treated RAW264.7 macrophages.
RNA-binding protein CUGBP1 controls the differential INSR splicing in molecular subtypes of breast cancer cells and affects cell aggressiveness.
Chrysin Inhibits Melanoma Tumor Metastasis via Interfering with the FOXM1/β-Catenin Signaling.
Indole alkaloids from leaves of Alstonia scholaris (L.) R. Br. protect against emphysema in mice.
miR-203 inhibits cell proliferation and ERK pathway in prostate cancer by targeting IRS-1.
Identification of long-term survival-associated gene in breast cancer.
bta-miR-23a Regulates the Myogenic Differentiation of Fetal Bovine Skeletal Muscle-Derived Progenitor Cells by Targeting MDFIC Gene.
Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage.
Efficacy of a wound-dressing biomaterial on prevention of postinflammatory hyperpigmentation after suction blister epidermal grafting in stable vitiligo patients: a controlled assessor-blinded clinical study with in vitro bioactivity investigation.
The critical role of the hippocampal NLRP3 inflammasome in social isolation-induced cognitive impairment in male mice.
MitoQ attenuates brain damage by polarizing microglia towards the M2 phenotype through inhibition of the NLRP3 inflammasome after ICH.
Anti-neuroinflammatory effect of 3,4-dihydroxybenzaldehyde in ischemic stroke.
The B7-H4 gene induces immune escape partly via upregulating the PD-1/Stat3 pathway in non-small cell lung cancer.
Protein target identification of ginsenosides in skeletal muscle tissues: discovery of natural small-molecule activators of muscle-type creatine kinase.
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Leptin mediates protection of hydrogen sulfide against 6-hydroxydopamine-induced Parkinson's disease: Involving enhancement in Warburg effect.
Neuropeptide Y1 receptor antagonist promotes osteoporosis and microdamage repair and enhances osteogenic differentiation of bone marrow stem cells via cAMP/PKA/CREB pathway.
A Novel Mechanism of bta-miR-210 in Bovine Early Intramuscular Adipogenesis.
Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep.
Synergistic antifibrotic effects of miR-451 with miR-185 partly by co-targeting EphB2 on hepatic stellate cells.
Synthesis and biological evaluations of N'-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents.
Mbd2 Mediates Retinal Cell Apoptosis by Targeting the lncRNA Mbd2-AL1/miR-188-3p/Traf3 Axis in Ischemia/Reperfusion Injury.
Yueju-Ganmaidazao Decoction confers rapid antidepressant-like effects and the involvement of suppression of NMDA/NO/cGMP signaling.
The developmental and experience-dependent expression of IGF-2 in mice visual cortex.
Overexpression of NRF1-742 or NRF1-772 Reduces Arsenic-Induced Cytotoxicity and Apoptosis in Human HaCaT Keratinocytes.
CRISPR/Cas9-mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen.
Circular RNA hsa_circ_0008285 inhibits colorectal cancer cell proliferation and migration via the miR-382-5p/PTEN axis.
Hepatic HuR modulates lipid homeostasis in response to high-fat diet.
Melatonin regulates mitochondrial dynamics and alleviates neuron damage in prion diseases.
PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition.
A novel microRNA and its pfk target control growth length in the freshwater shrimp Neocaridina heteropoda.
Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5.
Nucleus-located PDK1 regulates growth, invasion and migration of breast cancer cells.
Autophagy inducer activates Nrf2-ARE pathway to attenuate aberrant alveolarization in neonatal rats with bronchopulmonary dysplasia.
PCNA and GSK3β interact with each other to regulate H1299 lung adenocarcinoma cells apoptosis.
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis.
SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1-STAT3 Signaling in Human ES Cells.
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA(2) phosphorylation in experimental ischemic stroke.
Pizotifen inhibits the proliferation and invasion of gastric cancer cells.
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABA(A) receptors.
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma.
NCAPG Dynamically Coordinates the Myogenesis of Fetal Bovine Tissue by Adjusting Chromatin Accessibility.
Sodium butyrate causes α-synuclein degradation by an Atg5-dependent and PI3K/Akt/mTOR-related autophagy pathway.
Oxidative stress-mediated hepatotoxicity in rats induced by ethanol extracts of different parts of Chloranthus serratus.
Regulation of indoleamine 2, 3-dioxygenase in hippocampal microglia by NLRP3 inflammasome in lipopolysaccharide-induced depressive-like behaviors.
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2.
Inhibition of p38 MAPK regulates epileptic severity by decreasing expression levels of A1R and ENT1.
Tongmai formula improves cardiac function via regulating mitochondrial quality control in the myocardium with ischemia/reperfusion injury.
Radiosensitization Effect of AGuIX, a Gadolinium-Based Nanoparticle, in Nonsmall Cell Lung Cancer.
Adiponectin protects HL-1 cardiomyocytes against rotenone-induced cytotoxicity through AMPK activation.
Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.
Blood coagulation factor VIII D1241E polymorphism leads to a weak malectin interaction and reduction of factor VIII posttranslational modification and secretion.
Homocysteine downregulates cardiac homeobox transcription factor NKX2.5 via IGFBP5.
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Interplay of m(6)A and H3K27 trimethylation restrains inflammation during bacterial infection.
WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy.
Myricetin ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting TGF-β signaling via targeting HSP90β.
Lnc-M2 controls M2 macrophage differentiation via the PKA/CREB pathway.
Anti-Inflammatory Effect of Simonsinol on Lipopolysaccharide Stimulated RAW264.7 Cells through Inactivation of NF-κB Signaling Pathway.
Precise base editing with CC context-specificity using engineered human APOBEC3G-nCas9 fusions.
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.
Design, synthesis and biological evaluation of a novel tubulin inhibitor SKLB0565 targeting the colchicine binding site.
Hypoxia induces tumor cell growth and angiogenesis in non-small cell lung carcinoma via the Akt-PDK1-HIF1α-YKL-40 pathway.
The E3 ubiquitin ligase Smurf2 regulates PARP1 stability to alleviate oxidative stress-induced injury in human umbilical vein endothelial cells.
Monophosphoryl lipid A alleviated radiation-induced testicular injury through TLR4-dependent exosomes.
Inhibition of histone acetyltransferase GCN5 extends lifespan in both yeast and human cell lines.
The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity.
Exogenous H(2)S Induces Hrd1 S-sulfhydration and Prevents CD36 Translocation via VAMP3 Ubiquitylation in Diabetic Hearts.
Systemic MCPIP1 deficiency in mice impairs lipid homeostasis.
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
BH3 mimetic ABT-263 enhances the anticancer effects of apigenin in tumor cells with activating EGFR mutation.
The Binding of PD-L1 and Akt Facilitates Glioma Cell Invasion Upon Starvation via Akt/Autophagy/F-Actin Signaling.
Neuroprotective Effect of Echinacoside in Subacute Mouse Model of Parkinson's Disease.
Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1).
(-)-Epigallocatechin-3-gallate derivatives combined with cisplatin exhibit synergistic inhibitory effects on non-small-cell lung cancer cells.
Long-Term Effects of Zinc Deficiency and Zinc Supplementation on Developmental Seizure-Induced Brain Damage and the Underlying GPR39/ZnT-3 and MBP Expression in the Hippocampus.
Catalpol prevents denervated muscular atrophy related to the inhibition of autophagy and reduces BAX/BCL2 ratio via mTOR pathway.
Lipoxin A4 Regulates Lipopolysaccharide-Induced BV2 Microglial Activation and Differentiation via the Notch Signaling Pathway.
Protein kinase C-iota-mediated glycolysis promotes non-small-cell lung cancer progression.
Catalpol improves axonal outgrowth and reinnervation of injured sciatic nerve by activating Akt/mTOR pathway and regulating BDNF and PTEN expression.
LXRα Promotes the Differentiation of Human Gastric Cancer Cells through Inactivation of Wnt/β-catenin Signaling.
A Comparative Peptidomic Characterization of Cultured Skeletal Muscle Tissues Derived From db/db Mice.
TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease.
An improved Tet-on system in microRNA overexpression and CRISPR/Cas9-mediated gene editing.
Anti-TGEV Miller Strain Infection Effect of Lactobacillus plantarum Supernatant Based on the JAK-STAT1 Signaling Pathway.
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Integrating yeast chemical genomics and mammalian cell pathway analysis.
Sorafenib kills liver cancer cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids via the ATP-AMPK-mTOR-SREBP1 signaling pathway.
The oncogenic role of CB2 in the progression of non-small-cell lung cancer.
Interactions between β-cyclodextrin and tea catechins, and potential anti-osteoclastogenesis activity of the (-)-epigallocatechin-3-gallate-β-cyclodextrin complex.
Exosomal transfer of miR-501 confers doxorubicin resistance and tumorigenesis via targeting of BLID in gastric cancer.
USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway.
Deregulated lncRNA expression profile in the mouse lung adenocarcinomas with KRAS-G12D mutation and P53 knockout.
Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and hippocampi of adolescent mice.
Oxidation derivative of (-)-epigallocatechin-3-gallate (EGCG) inhibits RANKL-induced osteoclastogenesis by suppressing RANK signaling pathways in RAW 264.7 cells.
HIF-1α contributes to Ang II-induced inflammatory cytokine production in podocytes.
The CRISPR-Cas13a Gene-Editing System Induces Collateral Cleavage of RNA in Glioma Cells.
An LTR retrotransposon-derived lncRNA interacts with RNF169 to promote homologous recombination.
Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury.
Astaxanthin inhibits proliferation and induces apoptosis of LX‑2 cells by regulating the miR‑29b/Bcl‑2 pathway.
Sirt2 epigenetically down-regulates PDGFRα expression and promotes CG4 cell differentiation.
Fuplatin: An Efficient and Low-Toxic Dual-Prodrug.
Casp8 hypomethylation and neural tube defects in association with polycyclic aromatic hydrocarbon exposure.
The protective effects of XH-105 against radiation-induced intestinal injury.
Leonurine promotes neurite outgrowth and neurotrophic activity by modulating the GR/SGK1 signaling pathway in cultured PC12 cells.
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Long noncoding RNA CCAT2 promotes hepatocellular carcinoma proliferation and metastasis through up-regulation of NDRG1.
Protective effect of hyperoside against renal ischemia-reperfusion injury via modulating mitochondrial fission, oxidative stress, and apoptosis.
Role of Nkx2.5 in H(2)O(2)-induced Nsd1 suppression.
Long-term pulmonary exposure to multi-walled carbon nanotubes promotes breast cancer metastatic cascades.
Aloperine suppresses human pulmonary vascular smooth muscle cell proliferation via inhibiting inflammatory response.
PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol Efflux.
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats.
YAP mediates the positive regulation of hnRNPK on the lung adenocarcinoma H1299 cell growth.
Involvement of the microglial NLRP3 inflammasome in the anti-inflammatory effect of the antidepressant clomipramine.
Resveratrol protects against isoproterenol induced myocardial infarction in rats through VEGF-B/AMPK/eNOS/NO signalling pathway.
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA(2) phosphorylation.
Matrix Metalloproteases-Mediated Cleavage on β-Dystroglycan May Play a Key Role in the Blood-Brain Barrier After Intracerebral Hemorrhage in Rats.
Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells.
KIAA1199 promotes metastasis of colorectal cancer cells via microtubule destabilization regulated by a PP2A/stathmin pathway.
Echinacoside protects against MPTP/MPP(+)-induced neurotoxicity via regulating autophagy pathway mediated by Sirt1.
Activation of brain endothelium by Escherichia coli K1 virulence factor cglD promotes polymorphonuclear leukocyte transendothelial migration.
Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates.
Structural and functional damage to the hippocampal neurovascular unit in diabetes-related depression.
Exosomes from human adipose-derived stem cells promote sciatic nerve regeneration via optimizing Schwann cell function.
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Water-separated part of Chloranthus serratus alleviates lipopolysaccharide- induced RAW264.7 cell injury mainly by regulating the MAPK and Nrf2/HO-1 inflammatory pathways.
Hypoxic postconditioning activates the Wnt/β-catenin pathway and protects against transient global cerebral ischemia through Dkk1 Inhibition and GSK-3β inactivation.
Inhibition of dendritic spine extension through acrolein conjugation with α-, β-tubulin proteins.
Overexpression of ANLN in lung adenocarcinoma is associated with metastasis.
Crocin induces anti-ischemia in middle cerebral artery occlusion rats and inhibits autophagy by regulating the mammalian target of rapamycin.
RMI1 contributes to DNA repair and to the tolerance to camptothecin.
EIF4A2 interacts with the membrane protein of transmissible gastroenteritis coronavirus and plays a role in virus replication.
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
NKX2-2 Suppresses Osteosarcoma Metastasis and Proliferation by Downregulating Multiple Target Genes.
Caffeine Promotes Conversion of Palmitic Acid to Palmitoleic Acid by Inducing Expression of fat-5 in Caenorhabditis elegans and scd1 in Mice.
EGFR as a Negative Regulatory Protein Adjusts the Activity and Mobility of NHE3 in the Cell Membrane of IPEC-J2 Cells With TGEV Infection.
Involvement of NMDA-AKT-mTOR Signaling in Rapid Antidepressant-Like Activity of Chaihu-jia-Longgu-Muli-tang on Olfactory Bulbectomized Mice.
Effect of Black Tea Extract and Thearubigins on Osteoporosis in Rats and Osteoclast Formation in vitro.
Phosphorylation of IRS4 by CK1γ2 promotes its degradation by CHIP through the ubiquitin/lysosome pathway.
Effect of decabrominated diphenyl ether exposure on spatial learning and memory, the expression and phosphorylation of hippocampal glutamate receptor subunits in adult Sprague-Dawley rats.
iTRAQ-Based Proteomics Analysis Reveals the Effect of Rhubarb in Rats with Ischemic Stroke.
The Protective Effect of New Compound XH-103 on Radiation-Induced GI Syndrome.
PAX2 may induce ADAM10 expression in renal tubular epithelial cells and contribute to epithelial-to-mesenchymal transition.
Rapid induction of apoptosis in tumor cells treated with a new platinum(II) complex based on amino-thiazolidinone.
Theabrownin suppresses in vitro osteoclastogenesis and prevents bone loss in ovariectomized rats.
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Apolipoprotein E deficiency accelerates atherosclerosis development in miniature pigs.
hnRNPK modulates selective quality-control autophagy by downregulating the expression of HDAC6 in 293 cells.
Temporal Proteomic Analysis of Pancreatic β-Cells in Response to Lipotoxicity and Glucolipotoxicity.
Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells.
Horizontal transfer of exosomal CXCR4 promotes murine hepatocarcinoma cell migration, invasion and lymphangiogenesis.
KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.
The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43.
PMN inhibits colorectal cancer cells through inducing mitotic arrest and p53-dependent apoptosis via the inhibition of tubulin polymerization.
Met is involved in TIGAR-regulated metastasis of non-small-cell lung cancer.
Combined treatment with Dendrobium candidum and black tea extract promotes osteoprotective activity in ovariectomized estrogen deficient rats and osteoclast formation.
CCAAT/enhancer-binding protein β overexpression alleviates myocardial remodelling by regulating angiotensin-converting enzyme-2 expression in diabetes.
[USP33 suppresses lung adenocarcinoma lung cell invasion and metastasis by down-regulating SLIT2/ROBO1 signaling pathway].
PTEN-L promotes type I interferon responses and antiviral immunity.
Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex.
Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production.
Synergistic neuroprotective effect of rasagiline and idebenone against retinal ischemia-reperfusion injury via the Lin28-let-7-Dicer pathway.
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
The antidepressant effects of ɑ-tocopherol are related to activation of autophagy via the AMPK/mTOR pathway.
Pu-erh Tea Extract Ameliorates Ovariectomy-Induced Osteoporosis in Rats and Suppresses Osteoclastogenesis In Vitro.
Role of the Ubiquitin C-Terminal Hydrolase L1-Modulated Ubiquitin Proteasome System in Auditory Cortex Senescence.
Neural Plasticity Associated with Hippocampal PKA-CREB and NMDA Signaling Is Involved in the Antidepressant Effect of Repeated Low Dose of Yueju Pill on Chronic Mouse Model of Learned Helplessness.
Tail Nerve Electrical Stimulation and Electro-Acupuncture Can Protect Spinal Motor Neurons and Alleviate Muscle Atrophy after Spinal Cord Transection in Rats.
Regulatory Axis of miR-195/497 and HMGA1-Id3 Governs Muscle Cell Proliferation and Differentiation.
2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G(2)/M cell cycle arrest through generation of thiol oxidative stress in human esophageal cancer cells.
Nrf2 Promotes Keratinocyte Proliferation in Psoriasis through Up-Regulation of Keratin 6, Keratin 16, and Keratin 17.
Synthesis of β-tubulin occurs within chromatoid body of round spermatids.
PRAS40 alleviates neurotoxic prion peptide-induced apoptosis via mTOR-AKT signaling.
High expression of ubiquitin-specific peptidase 39 is associated with the development of vascular remodeling.
Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages.
MicroRNA-17-92 Regulates the Transcription Factor E2F3b during Myogenesis In Vitro and In Vivo.
CBX3 promotes colon cancer cell proliferation by CDK6 kinase-independent function during cell cycle.
cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases.
ERK1/2-mediated Cytoplasmic Accumulation of hnRNPK Antagonizes TRAIL-induced Apoptosis through Upregulation of XIAP in H1299 Cells.
Abl2 kinase phosphorylates Bi-organellar regulator MNRR1 in mitochondria, stimulating respiration.
20-Hydroxyeicosatetraenoic acid regulates the expression of Nedd4‑2 in kidney and liver through a neddylation modification pathway.
miR-34b Modulates Skeletal Muscle Cell Proliferation and Differentiation.
Alginate enhances Toll-like receptor 4-mediated phagocytosis by murine RAW264.7 macrophages.
Knockdown of RMI1 impairs DNA repair under DNA replication stress.
Overexpression of DBC1, correlated with poor prognosis, is a potential therapeutic target for hepatocellular carcinoma.
LL-37-induced human mast cell activation through G protein-coupled receptor MrgX2.
The mechanically activated p38/MMP-2 signaling pathway promotes bone marrow mesenchymal stem cell migration in rats.
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
The DEAD-Box RNA Helicase DDX3 Interacts with NF-κB Subunit p65 and Suppresses p65-Mediated Transcription.
Six2 Is a Coordinator of LiCl-Induced Cell Proliferation and Apoptosis.
RETRACTED: MicroRNA-378 Alleviates Cerebral Ischemic Injury by Negatively Regulating Apoptosis Executioner Caspase-3.
Up-regulation of miR-95-3p in hepatocellular carcinoma promotes tumorigenesis by targeting p21 expression.
Senkyunolide I attenuates oxygen-glucose deprivation/reoxygenation-induced inflammation in microglial cells.
Conventional protein kinase Cβ-mediated phosphorylation inhibits collapsin response-mediated protein 2 proteolysis and alleviates ischemic injury in cultured cortical neurons and ischemic stroke-induced mice.
The tumor suppressor PTEN has a critical role in antiviral innate immunity.
Hen egg white ovomacroglobulin promotes fibroblast migration via mediating cell adhesion and cytoskeleton.
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
Tubb3 regulation by the Erk and Akt signaling pathways: a mechanism involved in the effect of arginine ADP-ribosyltransferase 1 (Art1) on apoptosis of colon carcinoma CT26 cells.
Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers.
Inhibition of autophagy by 3-MA enhances IL-24-induced apoptosis in human oral squamous cell carcinoma cells.
Expression of Iodotyrosine Deiodinase in Thyroid and Other Organs in Iodine-Deficient and Iodine-Excess Rats.
Regulation of signal transducer and activator of transcription 3 and apoptotic pathways by betaine attenuates isoproterenol-induced acute myocardial injury in rats.
SCD1 negatively regulates autophagy-induced cell death in human hepatocellular carcinoma through inactivation of the AMPK signaling pathway.
Expression and localization of estrogen receptor in human breast cancer and its clinical significance.
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo.
Quantitative proteomic study of myocardial mitochondria in urea transporter B knockout mice.
The mechanisms of EGFR in the regulation of axon regeneration.
CXXC5 Associates with Smads to Mediate TNF-α Induced Apoptosis.
Downregulation of miR-181b in mouse brain following ischemic stroke induces neuroprotection against ischemic injury through targeting heat shock protein A5 and ubiquitin carboxyl-terminal hydrolase isozyme L1.
Modulation of calcineurin activity in mouse brain by chronic oral administration of cyclosporine A.
Effect of pioglitazone on altered expression of Aβ metabolism-associated molecules in the brain of fructose-drinking rats, a rodent model of insulin resistance.
Mutational analysis of ErbB2 intracellular localization.
Gong K, Song K, Wang H, Li L, Sun X, Sun L, Hao W, Chen ZS, Huang Y
International journal of biological sciences 2026;22(5):2215-2232
International journal of biological sciences 2026;22(5):2215-2232
Chondroitin sulfate alleviates osteoarthritis by upregulating HSPA8 to inhibit chondrocyte ferroptosis.
Jiang J, Xu Y, Dai T, Chen J, Li S, Meng Q
PloS one 2026;21(2):e0342242
PloS one 2026;21(2):e0342242
Epithelial Gab1 Restricts Sepsis-Induced Intestinal Injury by Orchestrating TNF/NF-κB Axis.
Jin W, Wu Y, Cheng X, Pan Y, He L, Xu Y, Xu J, Zhang X
Mediators of inflammation 2026;2026:5486971
Mediators of inflammation 2026;2026:5486971
Capg enhances proliferation, adipogenesis, and inflammatory response in preadipocytes: insights from bioinformatics analysis and functional validation.
Zhang L, Sang B, Li S, Li Y, Guo D, Ma Q, Liu X, Li X, Chen B, Liu D
PeerJ 2026;14:e20730
PeerJ 2026;14:e20730
NSMCE2 dispensability in mouse spermatogenesis suggests functional redundancy within the meiotic repair network.
Qin Z, Xiong Q, Wang M, Fang Y, Fan Q, Ma B, Gao Y, Cheng M, Cao Y, Zhang Y
Frontiers in cell and developmental biology 2026;14:1751806
Frontiers in cell and developmental biology 2026;14:1751806
RNF26 regulating tumor immunogenicity of hepatocellular carcinoma by degrading GRP78 and instigating ER stress.
Luo J, Zhuo H, Zheng M, Fang Y, Wang X, Jin Y, Li Y, Du S, Wang J, Xue C, Jiang R, Li G
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101375
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101375
RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability.
Peng S, Chen Y, Wu J, Huang X, Hong L, Xie Y, Lei Y, Wei X, Yang P, Zhang J, Yang Q, Liu G, Li A, Liu S, Li J, Dai W, Hu Y, Wang J, Xiong J, Wang J
International journal of oncology 2026 May;68(5)
International journal of oncology 2026 May;68(5)
BCR::ABL1 tyrosine kinase inhibitors induce ribosome collisions to activate ZAK-dependent ribotoxic stress and apoptosis in chronic myeloid leukemia.
Park J, Kim SH, Park J, Park H, Kim H, Kim DW, Lim C
Leukemia 2026 May;40(5):955-969
Leukemia 2026 May;40(5):955-969
β-Sitosterol Suppresses Osteoclastogenesis and Alleviates Bone Loss by Targeting Tmed10 to Inhibit RANKL-Induced Hedgehog/MAPK Signaling and ROS.
Huang W, Liu T, Liao J, Lian D, Zeng X, Yao Z, He M, Zhang X, Cai Z
Phytotherapy research : PTR 2026 May;40(5):2491-2513
Phytotherapy research : PTR 2026 May;40(5):2491-2513
Inhibitory effects of spermidine on lipopolysaccharide-induced inflammation in RAW 264.7 cells.
Yuan H, Peng F, Zhou YF, Wu SX, Long ZY, Peng YM, Zhou YZ
Experimental and therapeutic medicine 2026 May;31(5):124
Experimental and therapeutic medicine 2026 May;31(5):124
Small peptides derived from the autoinhibitory XY linker of phospholipase C-β isoforms inhibit enzyme activity and reduce inflammation.
de Andrés-López J, Cabañero D, Devesa I, Shah S, Fernández-Ballester G, Gamper N, Ángeles Bonache M, González-Muñiz R, Fernández-Carvajal A, Ferrer-Montiel A
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2026 May;198:119272
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2026 May;198:119272
Betrixaban activates cGAS and ERVs to promote dual nucleic-sensing antiviral immunity.
Chen X, Zhao Y, Xie Y, Liu T, Wang H, Wang X, Guo X, You F
EMBO molecular medicine 2026 May;18(5):1563-1591
EMBO molecular medicine 2026 May;18(5):1563-1591
Huzhang-Xiangbaji compounds enhance the repair of meniscal cartilage by inhibiting ferroptosis and inflammatory microenvironment.
Li J, Zhou J, Zhang G, Ding N, Kuang Z, Wang J, Liu N, Jia G, Jiang M, Wu S, Yang J, Ding X, Lei Z, Nie Y, Zhang Y, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158008
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158008
Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta-on-a-Chip Model.
Liu H, Wang Y, Cai Y, Guo R, Liu S, Chen T, Sun T, Huo R, Liu T, Lv Q, Wang X
Advanced healthcare materials 2026 May;15(18):e04027
Advanced healthcare materials 2026 May;15(18):e04027
AhR-Siglec-15 axis regulates lysosomal Ca2+ release for sonic hedgehog medulloblastoma growth via TRPML1.
Wang Z, Li S, Sun X, Wang D, Zhou Y, Zhou L, Chen J, Zhou N, Zhu Q, Liu J, Zhang G, Tong WM, Lv J, Huang B
Protein & cell 2026 May 1;17(5):438-451
Protein & cell 2026 May 1;17(5):438-451
Galangin 3-methyl ether alleviates mouse hypertrophic cardiomyopathy via targeting HDAC2 and subsequently inactivating the PI3K-AKT signaling pathway.
Zhang K, Xu T, Heng XY, Lei JZ, Han DS, Huang SH, He MQ, Pu L, Wu YY, Sun N, Yang H, Ye C
Acta pharmacologica Sinica 2026 Mar;47(3):636-651
Acta pharmacologica Sinica 2026 Mar;47(3):636-651
Lithospermic Acid Improves Doxorubicin-Induced Cardiomyopathy Through Sirtuin-3-Mediated Deacetylation of p53.
Zhao Y, Xu T, Ye C, Zhang K, Heng X, Huang S, Chen Y, Guo Y, Shao S, Wen Z, Shao C, Lu X, Sun N, Yang H
Phytotherapy research : PTR 2026 Mar;40(3):965-985
Phytotherapy research : PTR 2026 Mar;40(3):965-985
Baicalin Restores the Hypoglycemic Effect of Metformin by Regulating the Microbial Imidazole Propionate and Short-Chain Fatty Acids.
Wang A, Miao Z, Huang B, Zeng J, Yuan M, Yan D
Phytotherapy research : PTR 2026 Mar;40(3):1060-1073
Phytotherapy research : PTR 2026 Mar;40(3):1060-1073
Cytosolic nucleic acid sensing triggers type I interferon activation via the Hippo kinase LATS1.
Nass T Jr, Reichardt AD, Aliyari SR, Tom E, LeMunyan G, Parvatiyar MS, Cheng G, Parvatiyar K
The Journal of biological chemistry 2026 Mar;302(3):111204
The Journal of biological chemistry 2026 Mar;302(3):111204
Decreased Glucose Metabolism and Declined Chaperones Are Unique Features Required for the Survival of Senescent Fibroblasts and Pyruvate Dehydrogenase Is a Potent Senolytic Target.
Zhang M, Hu Z, Piao S, Song Y, Jia Y, Liu J, Zhao N, Liu A, Fu S, Sun W, Xu H, Yang Y, Gygi SP, Zhou C
Aging cell 2026 Mar;25(3):e70434
Aging cell 2026 Mar;25(3):e70434
Reversibly unlocking the blood-brain barrier: A study on microtubule dynamics modulation using gold nanoparticle-modified reduced graphene oxide.
Wu J, Cui G, Lin Z, Lin W, Zhang Y, Zhou T, He P, Zhang Y, Yao G
Acta pharmaceutica Sinica. B 2026 Mar;16(3):1676-1695
Acta pharmaceutica Sinica. B 2026 Mar;16(3):1676-1695
Royal jelly protein hydrolysates accelerate in vitro diabetic wound healing by enhancing keratinocytes functions and suppressing macrophage-mediated inflammation.
Lin T, Huang L, Lin A, Yuan Y, Cai R, Lin Z, Wang L, Lin Y, Su S
BMC complementary medicine and therapies 2026 Mar 9;26(1)
BMC complementary medicine and therapies 2026 Mar 9;26(1)
Targeting Apolipoprotein E4 rescues photoreceptor degeneration by inhibiting the disease-associated microglia activation in experimental retinal detachment.
Li X, Fan N, Yan Y, Ren M, Wu H, Dong K
Journal of neuroinflammation 2026 Mar 9;23(1)
Journal of neuroinflammation 2026 Mar 9;23(1)
STING Mediates Microglial Polarization to Promote Neuroinflammation in Epilepsy-Related Cognitive Dysfunction.
Yang H, Wang W, Liu X, Shi M, Wang H, Wu X, Liu Y, Yu Y
Neurochemical research 2026 Mar 25;51(2)
Neurochemical research 2026 Mar 25;51(2)
Dual targeting of PI3Kδ and PPARα enhances antitumor activity via FoxO1 activation in follicular lymphoma.
Wang W, Zhou H, Tan S, Qin D, Wang S, Xu C, Lei X, Li W, Wang L, Fu S, Jia S, Xu B, Zha J
Cell death & disease 2026 Mar 23;17(1)
Cell death & disease 2026 Mar 23;17(1)
GEF-H1 upon microtubule destabilization drives ZBP1-dependent necroptosis.
Zhang X, Li X, Yang Y, Wu J, Liu Q, Deng L, Huang J, Zhao Y, Ren J, Wu X
Cell death and differentiation 2026 Mar 17;
Cell death and differentiation 2026 Mar 17;
B3GNT3 facilitates NFKB2 processing and non-canonical NF-κB activation to drive lung adenocarcinoma progression.
Lin Y, Zhang Y, Yu B, Wang J, Wu Z, Wang H
Cellular oncology (Dordrecht, Netherlands) 2026 Mar 16;49(2)
Cellular oncology (Dordrecht, Netherlands) 2026 Mar 16;49(2)
Synergistic Anti-Tumor Activity of LRPPRC Inhibition and Dasatinib Through Dual Oxidative Phosphorylation Disruption.
Chen J, Gao L, Liang Y, Zhou W, Wang Y, Wang X, Fang X, Shao X
Pharmaceuticals (Basel, Switzerland) 2026 Mar 12;19(3)
Pharmaceuticals (Basel, Switzerland) 2026 Mar 12;19(3)
Tet methylcytosine dioxygenase 2(TET2)-dependent epigenetic regulation in the pathogenesis of polycystic ovary syndrome.
Liu K, Hong Y, Gao Q, Huang J, Liu L, Li Y, Liang Y, Zhang S, He X, Nie X
Cellular and molecular life sciences : CMLS 2026 Mar 11;83(1)
Cellular and molecular life sciences : CMLS 2026 Mar 11;83(1)
Amino acid supplementation enhances in vivo efficacy of lipid nanoparticle-mediated mRNA delivery in preclinical models.
Chen K, Wang W, Lennon A, McClure RA, Vuchkovska A, Kelley SO, Wang Z
Science translational medicine 2026 Mar 11;18(840):eadx4097
Science translational medicine 2026 Mar 11;18(840):eadx4097
Integrated fabrication of a shape-adaptable, antioxidative composite stent for effective closure and biological repair of enteroatmospheric fistula.
Qu G, Li Z, Yang S, Huang L, Liu Y, Li S, Liu J, Yu L, Ma R, Teng Y, Li H, Huang J, Ren J, Wu X
Bioactive materials 2026 Jun;60:55-73
Bioactive materials 2026 Jun;60:55-73
Geometry-driven immunomodulation in 3D-printed bioceramics: Negative curvature promotes macrophage M2 polarization via Ras-MAPK/HIF-1α signaling for vascularized osteogenesis.
Lu Q, Kuang Y, Diao J, Zheng J, Zhao N, Du C, Wang Y
Bioactive materials 2026 Jun;60:282-298
Bioactive materials 2026 Jun;60:282-298
Hepatic cavernous hemangioma decellularized extracellular matrix/GelMA composite hydrogel promotes angiogenesis via the ITGA9-FAK-ERK1/2 axis.
Dai Z, Li X, Jin M, Liu W, Li X, Zhang C, Li F, Lin J, Zhou Z, Sun X, Wang T, Yang H, Zhang J
Materials today. Bio 2026 Jun;38:102976
Materials today. Bio 2026 Jun;38:102976
Extracellular vesicle-mediated transcellular mitophagy as a modulatory target for moderate hyperoxia-induced alveolar developmental arrest in bronchopulmonary dysplasia.
Sun Y, Wang T, Yang Y, Wang R, Zhu B, Wang J, Liang G, Peng W, Zhang N, Guo X, Wang X
Free radical biology & medicine 2026 Jun;249:453-468
Free radical biology & medicine 2026 Jun;249:453-468
Polystyrene nanoplastics promote adipogenesis by stimulating nuclear translocation of PPARγ.
Zheng Y, Liu Z, Zhao Z, Sheng C, Li W, Tang D, Ning Y, Zhou R, Li A, Zhou Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jun;212:116030
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jun;212:116030
Design and synthesis of novel ATP-citrate lyase inhibitors and their effects on MAFLD/MASH.
Xu X, Wang Z, Wen H, Xie X, Hou T, Luo F, Zhou H, Wang J, Zhao Y, Liang X
European journal of medicinal chemistry 2026 Jun 5;310:118796
European journal of medicinal chemistry 2026 Jun 5;310:118796
Ailanthone ameliorates CCl(4)-induced liver fibrosis by targeting PKM2-mediated macrophage M1 polarization and glycolytic reprogramming.
Wan Y, Wang T, Wang K, Huo Q, Cheng X
International immunopharmacology 2026 Jun 15;179:116640
International immunopharmacology 2026 Jun 15;179:116640
Multi-omics analysis reveals Yishen Qutong formula promotes ferroptosis in Lewis lung cancer associated with Keap1/Nrf2/Nqo1 pathway modulation.
Li S, Cui Y, Zheng S, Yan Y, Jin Y, Chen Y, Yu J, Li Y, Feng L
Journal of ethnopharmacology 2026 Jun 12;364:121469
Journal of ethnopharmacology 2026 Jun 12;364:121469
Shaoyao Gancao Decoction alleviates ulcerative colitis-associated secondary liver injury by inhibiting the phosphorylation of pyruvate dehydrogenase in macrophages.
Tang F, Tang Y, Li L, Zhou F, Sun C, Ouyang B, Huang D, Li M, He W, Pei G, Tan Y
Journal of ethnopharmacology 2026 Jul 15;366:121652
Journal of ethnopharmacology 2026 Jul 15;366:121652
HOMER3 drives oral squamous cell carcinoma progression through TRPV6 calcium influx and TUBB3 microtubule stabilization.
Xu C, Zhang J, Zhang H, Chen L, Zhao J, Yang G, Xiao R, Zhu J, Fan C, Yao Y, Sun S
Oncogene 2026 Jan;45(2):278-294
Oncogene 2026 Jan;45(2):278-294
Neuroendocrine prostate cancer (NEPC)-associated CEP55 promotes cisplatin resistance in prostate cancer by regulating CDK1 phosphorylation.
Lai Z, Hu C, Jie J, Xiao Y, Zhu Y, Guo X, Liu Y, Wang Y, Pang S, Zeng X, Tan W, Wang Q
Cancer pathogenesis and therapy 2026 Jan;4(1):51-63
Cancer pathogenesis and therapy 2026 Jan;4(1):51-63
Polydopamine nanoparticle-enhanced stem cell spheroid-derived decellularized extracellular matrix with antioxidant and tissue-adhesive properties for brain repair.
Yang PC, Kao YC, Lin YP, Chen GH, Ho CH, Liu SW, Huang SC, Lee PY, Chen L, Huang CC
Biomaterials 2026 Jan;324:123530
Biomaterials 2026 Jan;324:123530
LncRNA FENDRR Inhibits Mitochondrial Apoptosis via TET2-Mediated DNA Demethylation of MFN1 in NSCPO.
Wu C, Liu H, Shan Z, Xia Y, Zhao P, Zhang Z, Yueguang G, Ma J
Oral diseases 2026 Jan;32(1):183-200
Oral diseases 2026 Jan;32(1):183-200
METTL1-mediated m7G methylation of FoxO1 regulates lipid metabolism in metabolic dysfunction-associated fatty liver disease.
Du J, Li Y, Zhu X, Gao J, Zhang Y, Wang C, Han D, Qiao L, Kou B, Guo R, Zhang H, Lin J
Metabolism: clinical and experimental 2026 Jan;174:156420
Metabolism: clinical and experimental 2026 Jan;174:156420
Nobiletin Ameliorates Skeletal Muscle Performance in D-Galactose-Induced Aging Mice by Boosting Aerobic Metabolism.
Wang H, Zhang Y, Zhang Y, Wang X, Li Y, Ren F, Sun Y
Food science & nutrition 2026 Jan;14(1):e71416
Food science & nutrition 2026 Jan;14(1):e71416
TNEA Regulates Hippocampal Oscillation by Improving Inhibitory Synaptic Plasticity to Ameliorates Cognitive Impairment in Alzheimer's Disease.
Guo Z, Ni H, Lu Y, Cui Z, Wang Y, Zhu Z, Wei X, Xia C, Xu M, Du L, Yang Y, Shu S, Wang K, Wang Z, Shan C, Wang D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(3):e10885
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(3):e10885
MXRA8, a key palmitoylation-related gene, promotes bladder cancer progression via remodeling tumor microenvironment and predicts poor prognosis.
Wang H, Xiong Y, He T, He M, Deng J, Song D, Wang Z
BMC urology 2026 Jan 8;26(1):34
BMC urology 2026 Jan 8;26(1):34
HuangLong oral liquid alleviates cough variant asthma in mice via inhibiting M2 macrophage chemotaxis and polarization by regulating the PI3K/AKT/ERK pathway.
Ji X, Fang W, Zhu X, Zhang Y, Zhu W, Long H
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120726
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120726
Neuroprotective effect of the herbal pair Coptidis Rhizoma-Cinnamomi Cortex against 6-OHDA-induced Parkinson's disease rats through promotion of autophagy via the PI3K/AKT/mTOR pathway.
Zhao Y, Ma Y, Xiong L, Ai J, Wang X, Chen X, Wang Y, Ba Y, Wu X
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120582
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120582
Multi-Targeted Therapeutic Mechanisms of Huangqi Guizhi Wuwu Decoction Against Rheumatoid Arthritis: An Integrated Approach Combining Serum Pharmacochemistry, Network Pharmacology, Metabolomics, and Experimental Validation.
Xu Z, Li Z, Qu J, Liang C, Zhang Y, Zhao Q, Li Q
Pharmaceuticals (Basel, Switzerland) 2026 Jan 29;19(2)
Pharmaceuticals (Basel, Switzerland) 2026 Jan 29;19(2)
Vascular smooth muscle cell RNA-binding protein U2AF2 induces copper death by regulating C1qbp expression, delaying development of atherosclerosise.
Yang Y, Chen H, Yu Q, Chen Q, Zhou X, Zhou S, Liu T, Lin J
Biological research 2026 Jan 28;59(1)
Biological research 2026 Jan 28;59(1)
In-situ RhoA editing via heparinylated LNP-microsphere system for rheumatoid arthritis treatment.
Zhu Y, Wang L, Wei Y, Li G, Shi Z, Wang D, Wang Q, Wang L, Si W, Yang X
Journal of nanobiotechnology 2026 Jan 23;24(1):166
Journal of nanobiotechnology 2026 Jan 23;24(1):166
Danthron Attenuates Intestinal Inflammation by Modulating Oxidative Stress via the EGFR-PI3K-AKT and Nrf2-HO-1 Pathways.
Ni C, Liu H, Jiang H, Lin Z, Wu K, Wang R, Yang H, Li W, Fan C, Zhao Y
Antioxidants (Basel, Switzerland) 2026 Jan 23;15(2)
Antioxidants (Basel, Switzerland) 2026 Jan 23;15(2)
Bone marrow-derived mesenchymal stem cells alleviate hepatic lipid metabolism disorders after scald injury: integrating liver transcriptome and metabolome.
Chen Z, Yang Y, Shi X, Yang R, Fang W, Liang G, Li Y, Gao J, Ma L, Yang J, Pang R
Stem cell research & therapy 2026 Jan 2;17(1):1
Stem cell research & therapy 2026 Jan 2;17(1):1
Defining the Critical Role of α-Gustducin for NF-κB Inhibition and Anti-Inflammatory Signal Transduction by Bitter Agonists in Lung Epithelium.
Fang Y, Wang Q, Wu S, He X, Wang S, Ma R, Zhao H, Zhao X, Wang X, Zhang Y
International journal of molecular sciences 2026 Jan 19;27(2)
International journal of molecular sciences 2026 Jan 19;27(2)
BRD4-mediated transcriptional activation of PDLIM4 enhances p21 stability and chemosensitivity in lung adenocarcinoma independent of p53.
Wang Q, Guo L, Wang S, Guan C, Pan J, Zhu S, Zheng L, Wu X, Gu Y, Shu T, Luo L, Lai T, Gao X
BMC biology 2026 Jan 17;24(1):37
BMC biology 2026 Jan 17;24(1):37
Size-dependent pyroptosis induction by calcium oxalate monohydrate crystals in HK-2 cells.
Chen XW, Tong XY, Tan RM, Ouyang JM
iScience 2026 Jan 16;29(1):114459
iScience 2026 Jan 16;29(1):114459
M1-like tumor-associated macrophages promote colorectal cancer progression through feedback activation of the IL1β/NF-κB signaling activity.
Xu X, Wang X, Luo Z, Parveen R, Zhang J, Zhou Y, Chen R, Ye Y, Guo J, Huang G, Wang Y, Ma G
International immunopharmacology 2026 Jan 1;168(Pt 1):115845
International immunopharmacology 2026 Jan 1;168(Pt 1):115845
Time-of-Day Defines the Risk of Thermally Abused Frying Oil to Renal Injury by Modulating the Diurnal Dynamics of Oxylipins.
Liu Y, Lu M, Du Y, Xu J, Fan M, Xue C, Liu Y
Exploration (Beijing, China) 2026 Feb;6(1):20240073
Exploration (Beijing, China) 2026 Feb;6(1):20240073
USP3 stabilizes MIC19 by deubiquitination under hypoxic stress and promotes the progression of non-small cell lung cancer.
Zhao WH, Huang H, Ding C, Zhao ZX, Jia CY, Wang YJ, Hu ZX, Wang GN, Li YW, Liu JH, Liu HY, Chen J
Acta pharmacologica Sinica 2026 Feb;47(2):391-403
Acta pharmacologica Sinica 2026 Feb;47(2):391-403
TERT activator compound alleviates cigarette smoke-induced cognitive deficits by modulating hippocampal inflammation and neurogenesis: A comprehensive study integrating Mendelian randomization.
Zheng Z, Chen C, Zhu S, Zhu X, Tu H, Ding X, Xia T, Gu X
Experimental neurology 2026 Feb;396:115543
Experimental neurology 2026 Feb;396:115543
Intranasal delivery of Odorranalectin-modified lipid nanoparticles for multi-targeted therapy of Alzheimer's disease.
Zhang Y, Yin C, Tian Y, Li X, Wang H, Han S, Chen H, Hou H
Materials today. Bio 2026 Feb;36:102764
Materials today. Bio 2026 Feb;36:102764
Genome-wide CRISPR screening identifies Annexin A1 as a facilitator of porcine astrovirus entry.
Luo Y, Dong Q, Yi S, Zhang W, Du Y, Fang Q, Zhang W, Ouyang K, Chen Y, Yin Y, Wei Z, Qin Y, Huang W
PLoS pathogens 2026 Feb;22(2):e1013943
PLoS pathogens 2026 Feb;22(2):e1013943
Exocarpium Citri Grandis-Derived Extracellular Vesicle-Like Particles for Accelerating Wound Healing via Regulating the Protein Expression on the VEGF/AKT Signaling Pathway.
Xiong Y, Luo Z, Zhao J, Fu C, Song Y, He J, Gao J, Su Z, Liu L, Teng X, Xu J
Food science & nutrition 2026 Feb;14(2):e71472
Food science & nutrition 2026 Feb;14(2):e71472
HMMR is a novel prognostic marker and a potential therapeutic target for colon cancer.
Fang L, Lin J, Huang D, Li J, Cui W, Deng M, Zhang Y
Cellular signalling 2026 Feb;138:112249
Cellular signalling 2026 Feb;138:112249
VDLIN: A Deep Learning-Based Platform for Methylcobalamin-Inspired Immunomodulatory Compound Screening.
Guo X, Zhao Y, Rong X, Niu C, Hu S, Liu Q, You F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(7):e13775
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(7):e13775
UBA5 deficiency disrupts mitochondrial autophagy via the PINK1-parkin pathway and impairs myoblast proliferation.
Shi H, Cai Y, Liu Y
Biological research 2026 Feb 5;59(1)
Biological research 2026 Feb 5;59(1)
Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics.
Kumari B, Damodaran AP, Guiblet WM, Xiao MS, Behera AK, On TA, McIntosh CE, Teszler M, Holloway C, Le S, Parab N, Zhao Y, Aregger M, Gonatopoulos-Pournatzis T
Nature communications 2026 Feb 3;17(1):1218
Nature communications 2026 Feb 3;17(1):1218
Succinate Mediates Immune-Angiogenic Response by Activating Macrophage M2 Polarization in Oxygen-Induced Retinopathy.
Shen T, Lin R, Zheng T, Yu J, Cai W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71545
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71545
Machine learning identifies a DNA repair-related risk model for bladder cancer and functionally characterizes ZWINT as a potential oncogenic factor.
Liang S, Liu H, Su Q, Li X, Yang Z, Mo W
Translational andrology and urology 2026 Feb 28;15(2):46
Translational andrology and urology 2026 Feb 28;15(2):46
Cepharanthine alleviated chronic prostatitis/chronic pelvic pain syndrome by activating Nrf2 and inhibiting the NF-κB pathway.
Zhang H, Zhang D, Wang Z, Liu K, Xu C, Sun H, Yan Z, Li C, Lu B, Yin Y, Zhao C, Niu Y, Li W
Biology direct 2026 Feb 26;21(1)
Biology direct 2026 Feb 26;21(1)
Deacetylation of BmHSP90 at Lysines 550/567 Stimulates Its Chaperone Function and Actin Polymerization to Drive the Proliferation of Bombyx mori Nucleopolyhedrovirus.
Wu YJ, Li JQ, Yang SY, Ma F, Shi XF, Yu W
Insects 2026 Feb 21;17(2)
Insects 2026 Feb 21;17(2)
VAMP7-dependent late endosomal secretion of ER and mitochondrial proteins impacts the tumor microenvironment and macrophage engagement.
Vats S, Dionisio P, Lemercier Q, Pineau R, Therreau L, Lipecka J, Cholley B, Moog JB, Wojnacki J, Keime C, Zala D, Bun P, Freire S, Domingues N, Danglot L, Guerrera IC, Delevoye C, Chevet E, Raimundo N, Galli T
Nature communications 2026 Feb 21;17(1)
Nature communications 2026 Feb 21;17(1)
DUX4-induced HSATII RNA accumulation drives protein aggregation, impacting RNA processing pathways.
Arends T, Bennett SR, Tapscott SJ
The Journal of cell biology 2026 Feb 2;225(2)
The Journal of cell biology 2026 Feb 2;225(2)
Taurine suppresses gastric intestinal metaplasia in patient-derived organoids and Atp4a (-/-) mice.
Liu K, Zhang X, Li FZ, Zheng PY, Mi Y
World journal of gastrointestinal oncology 2026 Feb 15;18(2):114161
World journal of gastrointestinal oncology 2026 Feb 15;18(2):114161
Y chromosome-linked EIF1AY deletion drives sex differences in multiple myeloma.
Feng Z, Bai J, Li Y, Li L, Zhang L
NPJ precision oncology 2026 Feb 14;10(1)
NPJ precision oncology 2026 Feb 14;10(1)
African swine fever virus DEAD-box helicase D1133L promotes OGG1-driven incision of genomic 8-oxoG via HDAC5 deacetylation.
Fan J, Yang J, Tian Z, Zhang X, Geng S, Luo J, Boldogh I, Zeng Q, Yin H, Guan G, Niu Q
Journal of molecular cell biology 2026 Feb 13;17(7)
Journal of molecular cell biology 2026 Feb 13;17(7)
The Bushen Huatan formula inhibits TP53-Mediated ferroptosis and modulating lipid metabolism in polycystic ovary syndrome abnormalities rat model.
Li X, Hu X, Yang J, Yue X, Deng L, Xiong Q
Journal of ovarian research 2026 Feb 10;19(1)
Journal of ovarian research 2026 Feb 10;19(1)
Gut microbial ammonia as a mediator of PFOS neurotoxicity and its remediation by the flavonoid Icaritin.
Yi Y, Zhang W, Wei Y, Ran W, Liu D, Deng W, Duan S, Yao J, Wang L, Zhang Y, Gao J, Gong Q
Gut microbes 2026 Dec 31;18(1):2620125
Gut microbes 2026 Dec 31;18(1):2620125
ARID1B regulates sphingolipid metabolism and myelin development via STAG2: Mechanistic insights into ARID1B-related coffin-siris syndrome.
Yang X, Gan Z, Zhou Y, Zhang M, Wu S, He F, Shen Z, Ma S, Su X, Xiong F
Cellular signalling 2026 Aug;144:112510
Cellular signalling 2026 Aug;144:112510
Yueju pill exerts long-lasting antidepressant effects through PACAP-mediated NG2 signaling and enhance hippocampal synaptic proteins.
Xing S, Peng Y, Wong NL, Wu C, Fu Z, Tan J, Xie H, Chen G, Zhang H
Journal of ethnopharmacology 2026 Aug 10;367:121682
Journal of ethnopharmacology 2026 Aug 10;367:121682
The GOLM1-ACLY pathway regulates macrophage-secreted EFEMP1 via H3K27ac modifications to drive tumor progression.
Zhen L, Min M, Mo X, Zhao G, Li H, Liu M, Wan L, Yang X, Huang L, Zhang Y, Gao Q, Zhong H, Qiang G, Wu F, Xie Q, Wei C, Zhao R
Journal of advanced research 2026 Apr;82:765-783
Journal of advanced research 2026 Apr;82:765-783
Loss of TRAIP Could Attenuate the Breast Cancer Cells Development by Regulating PLSCR4 Stabilization.
Dong Z, Chen Q, Li F, Xie W, Ma X, Ge S, Sun M, Zhao X, Zhang Z, Zhang W, Wei D, Huang S
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70825
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70825
Unlocking an Efficient SOD-to-CAT Catalytic Relay in a MOF Nanozyme via Dopamine-Driven Interfacial Nanoreconstruction for Osteoarthritis Therapy.
Li Z, Wu B, Li W, Marsili E, Tang K, Sun K, Cao Z, Zhang Y, Huang H, Li X, Wang G
Advanced materials (Deerfield Beach, Fla.) 2026 Apr;38(19):e72747
Advanced materials (Deerfield Beach, Fla.) 2026 Apr;38(19):e72747
RUVBL2 Regulates Microglia Metabolic Reprogramming to Mediate Stress Granules Aggregation Exacerbating Postoperative Delirium in Aged Mild Cognitive Impairment Rats.
Zhang L, Wang Z, Yang C, Wang X, Liu X, Zhang H, Liu H, Liao H, Chen J, Wang H
Aging cell 2026 Apr;25(4):e70458
Aging cell 2026 Apr;25(4):e70458
Neuronal phenotypic alterations and the therapeutic potential of Anxa2 in traumatic brain injury recovery.
Hu H, Zhang Y, Jin Y, Zhao J, Xing W, Wang Z, Liu J, Zhang B
Brain research bulletin 2026 Apr;237:111810
Brain research bulletin 2026 Apr;237:111810
Re-analysis of single-cell transcriptomics reveals a critical role of TNS1 gene in driving contractile VSMC transdifferentiation into macrophage-like SMC and atherosclerotic plaque instability.
Yang S, Fu R, Ren X, Sun M, Li Z, Chen S, Yang B, Shi N, Ye J, Shen C, Wang X, Cui Y, Wu N, Lu X, Gu D, Wang L
Clinical and translational medicine 2026 Apr;16(4):e70664
Clinical and translational medicine 2026 Apr;16(4):e70664
Targeting SLC5A2 suppresses colorectal tumour development by enhancing NK cell activity through extracellular vesicle-dependent MICA/B signalling.
Xiao J, Wu J, Deng F, Liu C, Chen Y, Shen K, Wang C, Lin W, Liu W, Ning Z, Zhou R, Zhao L
Clinical and translational medicine 2026 Apr;16(4):e70657
Clinical and translational medicine 2026 Apr;16(4):e70657
Celastrol disrupts the inflammatory feedback loop driven by Tenascin-C⁺ fibroblast subtype in psoriasis: Insights from single-cell RNA sequencing and experimental validation.
Ma Y, Zhang X, Chen X, Zhang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157988
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157988
PSAT1 Promotes NSCLC Progression via the De Novo Serine Synthesis Pathway and Represents a Therapeutic Vulnerability.
Zhou X, Zhao M, Cao Y, Zhou X, Wang K
Cancer medicine 2026 Apr;15(4):e71780
Cancer medicine 2026 Apr;15(4):e71780
Ascites circRNA ASCOR Drives Platinum Resistance of High-Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation.
Liu H, Zhu C, Yao X, Liu Y, Zhu J, Li Y, Xu H, Peng C, Shan G, Chen L, Zhou Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e18922
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e18922
CircPBX1 ameliorates metabolic memory-associated erectile dysfunction via miR-195-5p/YAP1-mediated angiogenesis in diabetic rats.
Luo CY, Luo JQ, Xia RF, Lu BX, He HY, Liao ZQ, He SH, Wu XB, Zhang HB, Hui JL
Communications biology 2026 Apr 8;
Communications biology 2026 Apr 8;
Evolutionarily conserved signaling intermediate in Toll pathways facilitates exercise-induced amelioration of skeletal muscle atrophy by maintaining mitochondrial quality control in middle-aged mice.
Fan J, Wen X, Duan X, Zhang X, Zhang T
The journals of gerontology. Series A, Biological sciences and medical sciences 2026 Apr 7;81(5)
The journals of gerontology. Series A, Biological sciences and medical sciences 2026 Apr 7;81(5)
Cardiomyocytes FGFBP1 induction by STAT3 drives pathological cardiac remodeling.
Shen Y, Wang J, Ye L, Liu R, Wu H, Luo X, Zhou Q, Wang L, Liang G, Xu Z
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 19;:168269
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 19;:168269
CuET inhibits Ewing sarcoma of bone progression through modulation of the ESM1-MAPK/ERK signaling axis.
Xu W, Jiang Z, Peng D
International immunopharmacology 2026 Apr 15;175:116444
International immunopharmacology 2026 Apr 15;175:116444
ADAM15 promotes the progression and metastasis of hepatocellular carcinoma by activating the JNK/p38 pathway.
Junhui X, Mengyun S
Scientific reports 2026 Apr 15;
Scientific reports 2026 Apr 15;
GM-CSF exacerbates pulmonary arterial hypertension via CCL2/CCR2-axis-mediated macrophage NLRP3 inflammasome activation.
Jiang R, Li L, Luo Y, Wang W, Zeng X, Qian C, Gong C, Sheng J
International immunopharmacology 2026 Apr 1;174:116394
International immunopharmacology 2026 Apr 1;174:116394
PRMT1-Mediated PARP1 Methylation Drives Lung Metastasis and Chemoresistance via P65 Activation in Triple-Negative Breast Cancer.
Zhang J, Huang Z, Song C, Wu S, Xie J, Zou Y, Xie X, Wu T, Yang H, Tang H
Research (Washington, D.C.) 2025;8:0854
Research (Washington, D.C.) 2025;8:0854
Eucommia ulmoides extract attenuates oxidative stress and promotes melanogenesis via Wnt/β-catenin signaling in B16 cells and mice.
Liu X, Qiu Y, Lv X, Chang L, Ji T, Gu Y, Chen S
Turkish journal of biology = Turk biyoloji dergisi 2025;49(7):790-799
Turkish journal of biology = Turk biyoloji dergisi 2025;49(7):790-799
Histone Methyltransferase EHMT2 Promotes the Progression of Breast Ductal Carcinoma by Regulating the Hippo Pathway.
Xiao Y, Song L, Xie WJ, Chen RW, Lin ZJ, Lin XY, Liu Y, Jiang Y, Xu S, Xu JP
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2025;44(3):63-74
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2025;44(3):63-74
A Mesoporous Silica-Based Naringenin Delivery System Promoting Macrophage M2 Polarization in Atherosclerosis.
Ren S, Liu J, Pu H, Wang P, Wu X, Qin J, Liu X, Yin M, Lu X, Li B, Zhao Z
Biomaterials research 2025;29:0248
Biomaterials research 2025;29:0248
Ginsenoside Rh2-Pretreated Mesenchymal Stem Cell Exosomes Ameliorate Collagen-Induced Arthritis via N6-Methyladenosine Methylation.
Zhou Z, Wu S, Li Y, Shao P, Jiang J
Biomaterials research 2025;29:0220
Biomaterials research 2025;29:0220
Inhibition of Mettl3 alleviates low-dose cisplatin-induced renal fibrosis and enhances the chemotherapeutic efficacy in mouse models of cancer.
Xie Y, Li H, Pan J, Li Y, Zhang D
International journal of biological sciences 2025;21(10):4293-4311
International journal of biological sciences 2025;21(10):4293-4311
Novel Duck Orthoreovirus σA Protein Inhibits Interferon Signaling by Impeding STAT1/STAT2 Nuclear Translocation.
Xu B, Jiang C, Di L, Zhou L, Wang Z, Tang Y, Fang R, Wang H
Transboundary and emerging diseases 2025;2025:8440800
Transboundary and emerging diseases 2025;2025:8440800
Hsa_circ_0006834 represses intrahepatic cholangiocarcinoma proliferation through activating AMPK-mTOR pathway and autophagy via has-miR-637-NGFR network.
Wang J, Qi X, Zhao W, Hao Z, Wang K, Li Y, Wang Y, Zhang Y
PloS one 2025;20(8):e0329847
PloS one 2025;20(8):e0329847
Accelerated peripheral nerve repair using surface-modified biomaterials for targeted capture of glial-derived growth factors post-neurorrhaphy.
Chen SJ, Lin CM, Liu CH, Chen YH, Hsieh YL, Lin YC, Chu YH, Ku CY, Liao WL, Liao WC
PloS one 2025;20(4):e0319979
PloS one 2025;20(4):e0319979
Plasma-activated media inhibits epithelial-mesenchymal transition and ameliorates intestinal fibrosis through the PPARγ/TGF-β1/SMAD3 pathway.
You Y, Shen Y, Yang Y, Wei X, Zhou Y, Tan F, Deng L, Du H, Wang S, Wang C, Huang Y
PloS one 2025;20(10):e0335225
PloS one 2025;20(10):e0335225
Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation.
Isei MO, Crockett M, Chen E, Rodwell-Bullock J, Carroll T, Girardi PA, Nehrke K, Johnson GVW
PloS one 2025;20(1):e0307358
PloS one 2025;20(1):e0307358
ROS-Responsive Nanosystem Targeted Co-Delivery YC-1 and Regorafenib to Alleviate Hypoxia Enhancing Hepatocellular Carcinoma Therapy.
Song L, Wu Y, Zhao S, Liu Y, Liu Z, Zhai Y, Cao J, Xia Y, Liang R, Wang W, Zhu R, Sun B, Shi Y, Sun Y
International journal of nanomedicine 2025;20:8481-8496
International journal of nanomedicine 2025;20:8481-8496
Lymph Node Exosomes Delivery Attenuates Myocardial Ischemia-Reperfusion Injury via Regulating PTEN-PI3K/Akt Pathway Mediated Myocardiocyte Apoptosis.
Qiao S, Wu B, Chen L, Ma L, Wang Y, Xu B, Gu R
International journal of nanomedicine 2025;20:4967-4981
International journal of nanomedicine 2025;20:4967-4981
Fibroblast Growth Factor 20 Attenuates Colitis by Restoring Impaired Intestinal Epithelial Barrier Integrity and Modulating Macrophage Polarization via S100A9 in an NF-κB-Dependent Manner.
Zhen D, Wang S, Liu Z, Xi Y, Du H, Wang N, Gao X, Lin Z, Wu F
Cellular and molecular gastroenterology and hepatology 2025;19(6):101486
Cellular and molecular gastroenterology and hepatology 2025;19(6):101486
Probiotic supplementation attenuated early-life chemotherapy-induced brain development impairment in mice.
Tan A, Chen J, Zhang J, Tong J, Jiang Z
Frontiers in behavioral neuroscience 2025;19:1697727
Frontiers in behavioral neuroscience 2025;19:1697727
NCAPG promotes the malignant progression of endometrioid cancer through LEF1/SEMA7A/PI3K-AKT.
Ren Z, Li X, Fu C
Journal of Cancer 2025;16(2):445-459
Journal of Cancer 2025;16(2):445-459
Cryptococcus neoformans phospholipase B1 is critical for cryptococcoma formation in the mouse brain.
Munzen ME, de Sousa Araújo GR, Hamed MF, Reguera-Gomez M, Lee HH, Pontes B, Alviña K, Frases S, Martinez LR
Frontiers in immunology 2025;16:1681033
Frontiers in immunology 2025;16:1681033
GDF15 is associated with thyroid cancer progression and may modulate thyroid cancer cell senescence in a p53-dependent manner.
Ma J, Liu Z, Hua R, Ding C, Yang Z, Liang W, Lv B
Frontiers in endocrinology 2025;16:1675245
Frontiers in endocrinology 2025;16:1675245
c-Met inhibitor NVP-BVU972 induces antiviral protection and suppresses NF-κB-mediated inflammation.
Xie Y, Zhao Y, Chen X, Jia H, Wang X, Liu T, Wang H, Li Y, Guo X, You F
Frontiers in immunology 2025;16:1651730
Frontiers in immunology 2025;16:1651730
To reveal biomarkers related to macrophage and lactic acid metabolism in renal fibrosis and explore their mechanisms.
Yong C, Yu Y, Wei Y, Huang G, Shu L, Gao K, Zhou E
Frontiers in immunology 2025;16:1609903
Frontiers in immunology 2025;16:1609903
Identification and evaluation of a pinocembrin analog as a TRPV1 inhibitor with analgesic properties in murine pain models.
Chen H, Li G, Deng L, Xu N, Lee SM, Nie X, Bian JS
Frontiers in pharmacology 2025;16:1585181
Frontiers in pharmacology 2025;16:1585181
Stimulation of regulatory dendritic cells suppresses cytotoxic T cell function and alleviates DEN-induced liver injury, fibrosis and hepatocellular carcinoma.
Wang J, Gong P, Liu Q, Wang M, Wu D, Li M, Zheng S, Wang H, Long Q
Frontiers in immunology 2025;16:1565486
Frontiers in immunology 2025;16:1565486
Phosphoglycerate kinase 1 as a potential prognostic biomarker in papillary thyroid carcinoma.
Shi XQ, Liu XT, Liu XH, Geng HW, Zhang Z, Wang WY, Chen X, Zhao X, Jue BL, Qin B, Liu PP
Frontiers in pharmacology 2025;16:1542159
Frontiers in pharmacology 2025;16:1542159
The integrated analysis of SIRT family expression, prognostic value, and potential implications in childhood acute lymphoblastic leukemia.
Xu X, Wang Z, Wang X, Zhang W, Luo Z, Zheng X, Pan R, Fu Y, Wang Y, Huang G, Chen R, Ma G
Frontiers in oncology 2025;15:1685249
Frontiers in oncology 2025;15:1685249
Hypoxia promotes pancreatic adenocarcinoma progression by stabilizing ID1 via TRIM21 suppression.
Cheng R, Tang Y, Cao X, Huang Z, Guo Y, Jin R, Wang Y, Liu Y, Xue L, Wang Y
Frontiers in oncology 2025;15:1616968
Frontiers in oncology 2025;15:1616968
Betrixaban is a broad anti-virus inhibitor by activating innate immunity.
Hu S, Zhao Y, Chen X, Wang H, Hu W, Huang R, Yang J, Niu C, Guo X, You F
Frontiers in cellular and infection microbiology 2025;15:1603530
Frontiers in cellular and infection microbiology 2025;15:1603530
Comprehensive Insights Into the Role of TRPM4 in Pan-Cancer Progression and Immune Regulation.
Chang W, Gao W, Luo B, Chen Y, Wen Z
ImmunoTargets and therapy 2025;14:831-848
ImmunoTargets and therapy 2025;14:831-848
Inhibitors of KAT2A Alleviate the Progression of AKI by Alleviating Macrophage Ferritinophagy.
Zuo Z, Gao S, Wang J, Liu Z, Lu Z, Wu H, Huang X, Yang C, Chen J, Liu H, Pan Q, Yang L
ImmunoTargets and therapy 2025;14:1515-1529
ImmunoTargets and therapy 2025;14:1515-1529
Peroxisome proliferator-activated receptors-mediated diabetic wound healing regulates endothelial cells' mitochondrial function via sonic hedgehog signaling.
Rui S, Xiao F, Li Q, Yang M, Dai L, Yu S, Zhang X, Jiang X, Ahn S, Wang W, Armstrong DG, Wang H, Huang G, Deng W
Burns & trauma 2025;13:tkaf063
Burns & trauma 2025;13:tkaf063
Spatiotemporal regulation of the bone immune microenvironment via a 'Zn(2+)-quercetin' hierarchical delivery system for bone regeneration.
Sun H, Chen Y, Sang X, Liu Q, Yu H, Hu S, Mao Y, Zhang L
Regenerative biomaterials 2025;12:rbaf006
Regenerative biomaterials 2025;12:rbaf006
Integrated Transcriptomic Analysis Leveraging Single-Cell and Bulk RNA Sequencing Data to Uncover Pyroptosis-Related Prognostic Signatures in HCC.
Li J, Di Y, Kang X, Song Z, Sun Z
Journal of hepatocellular carcinoma 2025;12:2971-2988
Journal of hepatocellular carcinoma 2025;12:2971-2988
Tremella fuciformis Polysaccharides Alleviate Early Brain Injury in Experimental Subarachnoid Hemorrhage by Inhibiting the KDR-Mediated P38 MAPK/NF-κB Pathway.
Wan YH, Cheng ZJ, Fan LX, Yang DH, Chen BL, Chen XX, Zhu Q
Molecular neurobiology 2025 Sep;62(9):11112-11129
Molecular neurobiology 2025 Sep;62(9):11112-11129
Phytosphingosine Alleviates Cigarette Smoke-Induced Bronchial Epithelial Cell Senescence in Chronic Obstructive Pulmonary Disease by Targeting the Free Fatty Acid Receptor 4.
Zhan Y, Deng Z, Yang R, Chen S, Zhang J, Zhang Y, Fu H, Huang Q, Gu Y, Zeng Z, Chen J, Zhang J, Wu J, Xie J
MedComm 2025 Sep;6(9):e70345
MedComm 2025 Sep;6(9):e70345
Single-protein/RNA imaging reveals ZNF598 as a limiting factor in resolving collided ribosomes.
De La Cruz AC, Tisdale G, Nakayama E, Huang Z, Sinha NK, Green R, Wu B
The EMBO journal 2025 Sep;44(18):5215-5232
The EMBO journal 2025 Sep;44(18):5215-5232
Hepatic ASPG-mediated lysophosphatidylinositol catabolism impairs insulin signal transduction.
Li F, Huang HS, Zhao Q, Zhang W, Shi T, Lv W, Zhu Q, Liu H, Xu Y, Huang H, Tang QQ, Gao Y, Peng T, Pan D
The EMBO journal 2025 Sep;44(18):5005-5036
The EMBO journal 2025 Sep;44(18):5005-5036
SARS-CoV-2 nucleocapsid protein delays cell cycle in S-phase.
Liu J, Liu M, Yu X, Wang PH, Guan X, Huo W, Zhang J, Cui M, Li X, Zhou X, Liu S, Wang C, Huang C, Yu J
International journal of medical microbiology : IJMM 2025 Sep;320:151671
International journal of medical microbiology : IJMM 2025 Sep;320:151671
Nuclear localization of platelet activating factor receptor accounts for microglial phagocytosis in ischemic stroke.
Zhang XY, Xu H, Ren XW, Li QX, Hong C, Chen YF, Yang J, Ji J, Guo RB, Sun XL
Neurobiology of disease 2025 Sep;213:107020
Neurobiology of disease 2025 Sep;213:107020
RHOD mediates ATG9A trafficking to promote autophagosome formation during autophagy in cancer.
Wang S, Ren J, Chi J, Guan Y, Zheng R, Wang J, Liu X, Huang H
Autophagy 2025 Sep;21(9):1976-1994
Autophagy 2025 Sep;21(9):1976-1994
Gut Microbiota Regulate Lipid Metabolism via the Bile Acid Pathway: Resistance to Hypoxia in Gansu Zokor (Eospalax cansus).
Yang M, Zhang Y, Li Z, Liu T, He J, Li J
Integrative zoology 2025 Sep;20(5):948-962
Integrative zoology 2025 Sep;20(5):948-962
Choline reduces inflammatory response and lipid accumulation in calf hepatocytes induced by NEFA via inhibiting ROS/ NF-κB/NLRP3 inflammasome axis.
Zhang R, Du X, Hu H, Chen J, Yu J, Wang L, Yao J, Liu S, Wang J, Cao Y
Molecular immunology 2025 Sep;185:116-126
Molecular immunology 2025 Sep;185:116-126
EcSnx27 facilitates in vitro release of Singapore grouper iridovirus and interacts with its major capsid protein.
Zhao Z, Cai J, Wang S, Liang Y, Qin C, Wu C, Li L, Zang YA, Yu Y, Chen J
Developmental and comparative immunology 2025 Sep;170:105455
Developmental and comparative immunology 2025 Sep;170:105455
DDIT4 knockdown suppresses venous malformation progression by inhibiting NF-κB signaling as a potential therapeutic target.
He Y, Lin J, Li Y, Cheng X, Wang T, Wang W, Zeng W, Li Y
Microvascular research 2025 Sep;161:104833
Microvascular research 2025 Sep;161:104833
AARS1-mediated Osterix lactylation promotes its transcriptional activity during osteoblast differentiation.
Nian F, Guo L, Fei Z, Yang M, Chen L, Zhang Y, Zhang B, Qian Y, Zhang Z
Acta histochemica 2025 Sep;127(3):152273
Acta histochemica 2025 Sep;127(3):152273
Gut Metabolite Indole-3-Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging-Related Myocardial Fibrosis.
Lu J, Wang H, Zhang H, Li J, Li H, Chen Q, Han D, Liu J, Lv L, Xiong J, Yuan K, Wei X, Sheng S, Liu F, Shi Y, Dong Z, Li Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e01070
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e01070
NFATc4 Promotes Lung Adenocarcinoma Progression via the CCNB1/CDK1 Pathway and Is a Potential Prognostic Biomarker.
Yang W, Wu X, Cai F, Guo Z, Xu Z, Peng Y, Yang Z, Zhang X
Cancer science 2025 Sep;116(9):2400-2412
Cancer science 2025 Sep;116(9):2400-2412
Genome-wide CRISPR/Cas9 screen identifies host factors for Newcastle disease virus replication.
Tian J, Wang Y, Zhou Z, Li Y, Chang C, Meng F, Shi W, Li H, Wang W, Wei Q, Liu H, Yang Z, Xiao S
Poultry science 2025 Sep;104(9):105421
Poultry science 2025 Sep;104(9):105421
Enhancement of spinal cord injury repair in rats using photo-crosslinked GelMA hydrogel combined with mitochondrial transplantation.
Gao W, Tang C, Hang D, Chen H, Li D, Yan Y, Wang W, Peng H, Wang X, Zhang E, Wei M, Zhang H, Wang X
Bioengineering & translational medicine 2025 Sep;10(5):e70040
Bioengineering & translational medicine 2025 Sep;10(5):e70040
Peroxisome Proliferator-Activated Receptor Gamma (PPARγ)-targeted Gel/Mg/Lip@Gigantol nanoplatform attenuates skin barrier disruption-associated aging in mice via NLRP3 suppression.
Jia X, Yuan R, Huang Y, Li X, Zhang R, He L, Yang Z
International journal of biological macromolecules 2025 Sep 5;328(Pt 1):147464
International journal of biological macromolecules 2025 Sep 5;328(Pt 1):147464
RfeA from Streptococcus suis serotype 2 triggers NLRP3/Caspase-1-dependent pyroptosis leading to blood-brain barrier disruption.
Gao S, Wu W, Xiao X, Li J, Lei S, Wang L, Han X, Lou Y
Veterinary research 2025 Sep 25;56(1):184
Veterinary research 2025 Sep 25;56(1):184
Jiao-Ai Decoction and active ingredients promoted angiogenesis to alleviate threatened abortion through miR-16 mediated VEGF/VEGFR signaling pathway.
Deng J, Jing S, Zhang M, Quan X, Hu X, Yun J, Geng T, Zhang Y, Zhang L
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120385
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120385
Integration of network pharmacology and transcriptomics to reveal the mechanism of Paeoniae Radix Alba Polysaccharide in alleviating hepatic fibrosis.
Fan X, Gao J, Liu S, Hua J, Shao D, Jia L, Shen Y, Wang Z, Jin Z, Wang J
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120357
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120357
Inhalation of Mesenchymal-Stem-Cell-Derived Nanovesicles Delivering Catalase Enhances the Treatment for Acute Lung Injury.
Zhang L, Yan X, Li X, Huang Y, Wang X, Lin J, Zhang H, Liu Z, Guo Q
ACS nano 2025 Sep 23;19(37):33184-33201
ACS nano 2025 Sep 23;19(37):33184-33201
Lithospermic acid improves diabetic kidney fibrosis by regulating Piezo1/TGF-β1/Smad signaling pathway.
Yan Y, Wang C, Luo S, Hong T, Niu W, Sun X, Zhang E, Yang M, Li Z, Liu J, Zheng Z, Li J
European journal of pharmacology 2025 Sep 15;1003:177896
European journal of pharmacology 2025 Sep 15;1003:177896
MSTRG.118323.5 targets BAG5 as a miR-200-y sponge to regulate Sertoli cells apoptosis via PI3K/AKT/mTOR pathways of Bactrian camels.
Nan J, Liu Y, Wang R, Yan Q, Zhang Y, Wang Q, Zhao X
International journal of biological macromolecules 2025 Sep 11;328(Pt 2):147638
International journal of biological macromolecules 2025 Sep 11;328(Pt 2):147638
Reduced mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology.
Qin Y, Zhu W, Guo T, Zhang Y, Xing T, Yin P, Li S, Li XJ, Yang S
Neural regeneration research 2025 Sep 1;20(9):2655-2666
Neural regeneration research 2025 Sep 1;20(9):2655-2666
Reduced growth and biofilm formation at high temperatures contribute to Cryptococcus deneoformans dermatotropism.
Charles-Niño CL, Desai GM, Koroneos N, Hamed MF, Jain N, Lopes W, Braswell A, Linares A, Munzen ME, Nosanchuk JD, Vainstein MH, Martinez LR
Disease models & mechanisms 2025 Sep 1;18(9)
Disease models & mechanisms 2025 Sep 1;18(9)
Influence of Sevoflurane Postconditioning on Hypoxic-Ischemic Brain Injury via Nrf2-Regulated Ferroptosis in Neonatal Rats.
Li C, Wu Z, Xue H, Gao Q, Kuai S, Zhao P
Anesthesia and analgesia 2025 Sep 1;141(3):648-659
Anesthesia and analgesia 2025 Sep 1;141(3):648-659
TAP1 promotes immune escape by activating JNK/STAT1/PD-L1 signaling in EBV-associated gastric cancer.
Shan W, Li G, Zhang H, Zhang R, Liu J, Gao L, Li Y, Fan L, Yang C, Liu J
Molecular and cellular biochemistry 2025 Oct;480(10):5429-5446
Molecular and cellular biochemistry 2025 Oct;480(10):5429-5446
OTUD1 downregulates PD-L1 expression by deubiquitinating STAT3 and promotes the immune response in ccRCC.
Liang H, Liu X, Guo W, Xiong W, Ren D, Liu W
Cellular oncology (Dordrecht, Netherlands) 2025 Oct;48(5):1349-1361
Cellular oncology (Dordrecht, Netherlands) 2025 Oct;48(5):1349-1361
Tailoring the therapeutic potential of stem cell spheroid-derived decellularized ECM through post-decellularization BDNF incorporation to enhance brain repair.
Kao YC, Yang PC, Lin YP, Chen GH, Liu SW, Ho CH, Huang SC, Lee PY, Chen L, Huang CC
Biomaterials 2025 Oct;321:123332
Biomaterials 2025 Oct;321:123332
MitoQ alleviates prion-induced neurodegeneration by modulating DRP1- and OPA1-mediated mitochondrial dynamics.
Wu W, Zhang X, Xing J, Kong S, Jiang M, Zhou M, Liao Y, Liao B, Ma N
Free radical biology & medicine 2025 Oct;238:582-594
Free radical biology & medicine 2025 Oct;238:582-594
Endogenous synthesis of n-3 PUFAs can reduce lipid synthesis in Fad3 transgenic cattle.
Li D, Gao Y, Zhao X, Yun Y, Bo C, Song L, Yang L, Bai C, Li G, Su G
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Oct;1870(7):159672
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Oct;1870(7):159672
Propofol-mediated inhibition of ovarian function by mitophagy over-activation via TGF-β1/SMAD2/3 signaling pathway.
Miao L, Chen M, Zhou Y, Pan S, Li X, Wang Y, Zhang J, Zhu X
Cellular signalling 2025 Oct;134:111916
Cellular signalling 2025 Oct;134:111916
Cancer Cell-Derived Large Extracellular Vesicles Promote Venous Thromboembolism by Activating NETosis Through Delivering CYBA.
Li X, Ju Y, Xu C, Ma S, Sun L, Guo Q, Liu M, Xie Y, Min L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(37):e07867
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(37):e07867
Nanovesicles Synergistically Regulate Ferroptosis Characteristic Macrophage-Induced Angiogenesis via Ferritin Heavy Chain 1/Glutathione Peroxidase 4 Pathway to Promote Peripheral Nerve Regeneration.
Huo N, Xu G, Zhou H, Liu Y, Li S, Yang X, Liu J, Wang W, Yang N, Zhou N
ACS applied materials & interfaces 2025 Oct 8;17(40):55876-55894
ACS applied materials & interfaces 2025 Oct 8;17(40):55876-55894
Identification of human RNA Polymerase II interactors at early stages of transcription.
Ozer A, Kang JJ, Tang Y, Yugandhar K, Yu S, DeBerardine MD, Omar K, Lis JT, Yu H
bioRxiv : the preprint server for biology 2025 Oct 8;
bioRxiv : the preprint server for biology 2025 Oct 8;
ANK3 Is Regulated by Recursive Splicing and Inhibits Hepatocellular Carcinoma Metastasis by Inhibiting E-Cadherin Protein Degradation.
Guo Y, Fu X, Tian Y
Frontiers in bioscience (Landmark edition) 2025 Oct 30;30(10):46013
Frontiers in bioscience (Landmark edition) 2025 Oct 30;30(10):46013
Rosmarinic acid improves intestinal barrier integrity through PI3K/AKT/Nrf2-mediated regulation of tight junction protein expression.
Tang L, Deng J, Shi P, Zou S, Ran H, Yin F, Liu J
International immunopharmacology 2025 Oct 30;164:115380
International immunopharmacology 2025 Oct 30;164:115380
The activation of hippocampus microglia in the occurrence of airway hyperresponsiveness comorbidity anxiety.
Zhang H, Zhou Y, Liu Y, Zhao K, Chen H, Liu Q, Wang Q, Zhi J, Xu J, Yang D
Journal of neuroinflammation 2025 Oct 28;22(1):249
Journal of neuroinflammation 2025 Oct 28;22(1):249
PADI2 exacerbates Mycoplasma ovipneumoniae-induced lung injury in sheep by suppressing M2 macrophage polarization.
Yan C, Dong T, Zhang C, Liu M, Zhang Y
Veterinary research 2025 Oct 27;56(1):203
Veterinary research 2025 Oct 27;56(1):203
Cephalomannine as in vitro and in vivo anticancer agent in mesothelioma cells: mechanisms of action.
Morani F, Dell'Anno I, Daga A, Doccini S, Bisceglia L, Gemignani F, Landi S
BMC cancer 2025 Oct 22;25(1):1625
BMC cancer 2025 Oct 22;25(1):1625
Menaquinone-4 ameliorates abdominal aortic aneurysm by suppressing ferroptosis through NRF2/GCLM axis.
Zhou Z, Huang L, Wu D, He R, Zhou Y, Wang K, Wang R, Yao C
Gene 2025 Oct 20;970:149785
Gene 2025 Oct 20;970:149785
PTEN-L dephosphorylates Parkin and Ub Ser65 to aggravate mitophagy dysfunction in prion disease cell models.
Li X, Li J, Gou F, Dai Y, Zhao M, Wang D, Sun Z, Wen P, Wang J, Fan Q, Ma T, Wang X, Zhao D, Yang L
Life sciences 2025 Oct 15;379:123860
Life sciences 2025 Oct 15;379:123860
Exosomal transfer of miR-375-3p from pancreatic β cells to hepatocytes impairs hepatic glycogenesis via Rbpj repression.
Xu FZ, Dou L, Wu X, Xia CX, Yu DN, Man Y, Shen T, Huang XQ
World journal of diabetes 2025 Oct 15;16(10):109815
World journal of diabetes 2025 Oct 15;16(10):109815
Panax notoginseng Flower Extract Attenuates Pentylenetetrazole-Induced Epilepsy by Restoring Glutamate Homeostasis.
Zhao Y, Zhu F, Xie J, Wang Y, Matsabisa M, Tang M
Brain sciences 2025 Oct 15;15(10)
Brain sciences 2025 Oct 15;15(10)
Corilagin regulates antigen processing and presentation by directly binding to inhibit ERAP1.
Sun X, Zhou Y, Yu S, Liu X, Wu J, Zhou Y, Bai J, Li D, Xu H, Cao H
International immunopharmacology 2025 Oct 10;163:115180
International immunopharmacology 2025 Oct 10;163:115180
Rab26-mediated lysosomal translocation of eEF1A alleviates myocardial hypertrophy and cardiac remodeling.
Tong Y, Li Y, Bi Y, Liu Y, Peng X, He B, Wang X
Life sciences 2025 Oct 1;378:123830
Life sciences 2025 Oct 1;378:123830
A BACH1 inhibitor ameliorates myocardial infarction and limb ischemia in mice.
Lin J, Liu X, Li Q, Ge F, Ma J, Ng X, Pan Q, Wei X, Jiang Q, Jin J, Ma S, He Y, Li Y, Jiang N, Hou Y, Yu Y, Lin X, Jin Q, Xu C, Wang X, Zhi X, Liang Q, Jiang L, Osto E, Guo J, Wang XJ, Meng D
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Oct 1;33(10):5192-5211
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Oct 1;33(10):5192-5211
Nuclearporin subcomplex Nup98/Rae1 is vital for maternal-to-zygotic transition during early embryonic development.
Anfeng L, Hao G, Ali A, Mengfan Q, Kaixin P, Changfan Z, Wei Z, Song L, Hongyan R, Yanzhen B, Fan C
Theriogenology 2025 Oct 1;245:117519
Theriogenology 2025 Oct 1;245:117519
Mangiferin targets PFKFB3 to inhibit glioblastoma progression by suppressing glycolysis and PI3K/AKT/mTOR signaling.
Xia J, Li X, Yao J, Song D, Gu Z, Zheng G, Tu C
Brain research bulletin 2025 Oct 1;230:111520
Brain research bulletin 2025 Oct 1;230:111520
MicroRNA-592 suppresses breast cancer progression by targeting CYP20A1 to modulate the CHOP pathway.
Pan R, Jiang S, Su J, Zhang C, Li X, He K
Journal of physiology and biochemistry 2025 Nov;81(4):1173-1184
Journal of physiology and biochemistry 2025 Nov;81(4):1173-1184
Molecular mechanism of the crosstalk between glucocorticoid receptor (GR) and hypoxia-inducible factor 3α (HIF-3α) pathways.
Zhang M, Guo Y, Diao X, Guo M, Teng H, Sun X, Zhuang J, Song C, Xie X, Wu D
Marine life science & technology 2025 Nov;7(4):779-791
Marine life science & technology 2025 Nov;7(4):779-791
Activation of the C3 Complement Pathway in the Hippocampus Produces Anxiodepressive Effects in a Mouse Model of Inflammation Pain.
Zhang A, Zhang X, Tang X, Liu M, Xie J, Li S, Cao W, Zhou H, Xu Y
Molecular neurobiology 2025 Nov;62(11):14032-14049
Molecular neurobiology 2025 Nov;62(11):14032-14049
Fingolimod Exerts Therapeutic Effects on Autistic Mice via Improving the Structure and Function of Meningeal Lymphatics.
Hong C, Xiao HL, Sun ZH, Guo RB, Zhang XY, Ji J, Sun XL
CNS neuroscience & therapeutics 2025 Nov;31(11):e70649
CNS neuroscience & therapeutics 2025 Nov;31(11):e70649
HAX1 mediates SARS-CoV-2 spike-triggered unfolded protein response in host cells.
Zhu F, Sheng X, Yang F, Wang X, Yang C, Ren J, Wang C, Hu R
The FEBS journal 2025 Nov;292(22):5948-5964
The FEBS journal 2025 Nov;292(22):5948-5964
Very high-dose vitamin D₃ supplementation reduces the expression of genes and proteins engaged in β-oxidation in healthy pigs.
Steg A, Smołucha G, Świątkiewicz M, Oczkowicz M
The Journal of steroid biochemistry and molecular biology 2025 Nov;254:106835
The Journal of steroid biochemistry and molecular biology 2025 Nov;254:106835
Treadmill exercise alleviates STING-mediated microglia pyroptosis and polarization via activating mitophagy post-TBI.
Chen J, Zhu T, Yang X, Yang Z, Shen M, Gu B, Wang D, Zhang Y, Zhang M, Sun S, Yu J, Yan C
Free radical biology & medicine 2025 Nov;239:155-176
Free radical biology & medicine 2025 Nov;239:155-176
Discovery of KMT5A repressed miR-99b cluster with potential to restore chemotherapy sensitivity in gastric cancer by regulating mitochondrial complex II and affecting OXPHOS.
Niu L, Kang X, Zheng J, Wu F, Liu S, Hong L, Liu H, Wang J, Fan D, Nie Y, Chen Z
Pharmacological research 2025 Nov;221:107996
Pharmacological research 2025 Nov;221:107996
Analysis of antiviral functions, differences and apoptotic effects of two novel MHC-Iα genotypes in orange-spotted grouper (Epinephelus coioides).
Chen J, He X, Meng B, Wang L, Li S, Ouyang W, Sun Y, Qin Q, Yang M
Fish & shellfish immunology 2025 Nov;166:110571
Fish & shellfish immunology 2025 Nov;166:110571
USP20 competitively binds to STUB1 to enhance CTSL expression and promote epithelial-mesenchymal transition in head and neck squamous cell carcinoma.
Guo L, Zhang B, Cui X, Wang X, Xiao J, Miao S, Song K, Sun J
Clinical and translational medicine 2025 Nov;15(11):e70520
Clinical and translational medicine 2025 Nov;15(11):e70520
Brain endothelial HIF-1α exacerbates diabetes-associated cognitive impairment by accelerating glycolysis-driven lactate production.
Chen J, Lin R, Jiang C, Chen F, Li W, Wang L, Pan K, Zhang J, Yin Z, Huang Y
Acta pharmaceutica Sinica. B 2025 Nov;15(11):5772-5788
Acta pharmaceutica Sinica. B 2025 Nov;15(11):5772-5788
Understanding the impact of glycolysis and oxidative stress on residual feed intake in slow-growing chicken.
Niyomphong R, Kaewsatuan P, Pengsanthia S, Molee W, Molee A
Poultry science 2025 Nov;104(11):105816
Poultry science 2025 Nov;104(11):105816
circ_0000132 Regulates Chicken Granulosa Cell Proliferation Apoptosis and E2/P4 Synthesis via miR-206 E2F5 Signaling.
Yang H, Li W, Fu G, Liu S, Ma T
International journal of molecular sciences 2025 Nov 5;26(21)
International journal of molecular sciences 2025 Nov 5;26(21)
DDX1 facilitates lenvatinib resistance in hepatocellular carcinoma through regulating ephrin-A3 and activating the Wnt/β-catenin signaling pathway.
Huang S, Wang H, Fu S, Cheng F, Liu K, Wu J
Functional & integrative genomics 2025 Nov 4;25(1):230
Functional & integrative genomics 2025 Nov 4;25(1):230
MYST1-Mediated Lysine Acetylation Stabilizes KLF4 to Promote Intimal Hyperplasia.
Wang S, Liu Z, Wen J, Zhang C, Wu F, Zeng Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 30;39(22):e71247
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 30;39(22):e71247
Elevating cytosolic NADPH metabolism in endothelial cells ameliorates vascular aging.
Wu D, Tan B, Cheng Z, Li H, Li H, Yin Y, Ma F, Chen T, Dong X, Wang W, Hu Q
Nature communications 2025 Nov 3;16(1):9667
Nature communications 2025 Nov 3;16(1):9667
Regulatory role of sirtuin-1 by targeting MDM2 to mitochondria-associated membranes formation in the treatment of NAFLD.
Zhang R, Zhang Q, Cui Z, Huang B, Li M, Ma H
Cell communication and signaling : CCS 2025 Nov 28;23(1):514
Cell communication and signaling : CCS 2025 Nov 28;23(1):514
Cisplatin-encapsulated zeolitic imidazolate framework-8 nanosystem enhanced radiosensitivity of non-small cell lung cancer.
Yang R, Xie H, Wu H, Liu X, Luo J, Han L, Zhang M, Bao Z, Gong Y, Xie C
Scientific reports 2025 Nov 28;15(1):42758
Scientific reports 2025 Nov 28;15(1):42758
Acetylbinankadsurin A Decreases Macrophage Glycolysis and Pro-Inflammatory Phenotype Polarization via Inhibiting HIF-1α to Alleviate Hepatic Fibrosis in Mice.
Yao Q, Peng W, Lu H, Yang Y, Rao Z, Xie X, Huang D, Wang W, Yan J, Liu J
Molecules (Basel, Switzerland) 2025 Nov 27;30(23)
Molecules (Basel, Switzerland) 2025 Nov 27;30(23)
GDF11 alleviates glucocorticoid-induced osteonecrosis of the femoral head by regulating angiogenesis via the PI3K-AKT-eNOS pathway.
Liu Z, Yu L, Zhang Y, Liu K, Zhai H, Xu X, Lu Q, Li X, Li Z, Yang J, Li S, Si M, Cheng L, Liu P, Sun H
Communications biology 2025 Nov 25;8(1):1682
Communications biology 2025 Nov 25;8(1):1682
Tunneling nanotube-mediated stem cell immunomodulation dysfunction promotes adipose inflammation and insulin resistance in GDM.
Chen B, Chen X, Li J, Hu R, Yang L, Li H, Liu X, Cannon RD, Saffery R, Novakovic B, Qi H, Zhang H, Zhou X
Cell reports 2025 Nov 25;44(11):116505
Cell reports 2025 Nov 25;44(11):116505
Zhenqi Fuzheng Granule targets the SCFAs-GPR109A axis to enhance PD-1 antibody efficacy via immunometabolic remodeling in colorectal cancer.
Guo L, Yi J, Zhang A, Zheng X, Wang M, Yang F, Kong X, Meng J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157312
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157312
MPP(+) disorders Irg1-Itaconate axis to promote M1 polarization of microglia by activating succinate dehydrogenase.
Wang LY, Tang YY, Zou W, Zhang P, Tang XQ, Zhang P
Molecular biology reports 2025 Nov 24;53(1):115
Molecular biology reports 2025 Nov 24;53(1):115
Design, Synthesis and Anticancer Activity of 6-Substituted-1-(3,4,5-trimethoxyphenyl)-1H-indole Against Tubulin Polymerisation.
Gu Y, Gai C, Zou S, Song Y, Zhang J, Zhao Q, Chai X, Wang P
Molecules (Basel, Switzerland) 2025 Nov 24;30(23)
Molecules (Basel, Switzerland) 2025 Nov 24;30(23)
PD-L1(+) neutrophils trigger pulmonary endothelial pyroptosis via an oxidative phosphorylation-dependent mechanism in sepsis.
Ma C, Wang L, Wang X, Zhu X, Chen Y
Respiratory research 2025 Nov 24;26(1):327
Respiratory research 2025 Nov 24;26(1):327
Dynamic remodelling of epithelial plasticity in colorectal cancer from single-cell and spatially resolved perspectives.
Xu C, Pan Y, Zhang S, Lin M, Liu H, Yu Z
Journal of translational medicine 2025 Nov 24;23(1):1341
Journal of translational medicine 2025 Nov 24;23(1):1341
Roseburia hominis enriched by baicalin reverses the non-response to metformin via upregulating linolenic acid metabolism.
Miao Z, Long J, Huang B, Yan D, Wang A
iScience 2025 Nov 21;28(11):113892
iScience 2025 Nov 21;28(11):113892
Identification of novel biomarkers for hypertension and ventricular remodeling based on transcriptomics and machine learning.
Li Z, Zhang B, Chao L, Tian X, Chen W, Liu C, Tian H
iScience 2025 Nov 21;28(11):113668
iScience 2025 Nov 21;28(11):113668
N7-methylguanosine-related gene decapping scavenger enzymes as a novel biomarker regulating epithelial cell function in diabetic foot ulcers.
Xiao FG, Yang Z, Yu SY, Li Q, Huang PC, Huang GB, Li XG, Ran JL, Rui SL, Deng WQ
World journal of diabetes 2025 Nov 15;16(11):109455
World journal of diabetes 2025 Nov 15;16(11):109455
A novel angiotensin II type 2 receptor antagonist TDI05 alleviates the peripheral neuropathic pain.
Mao Q, Zeng Y, Liang H, Hou S, Wang Q, Zhang J, Lan Z, Wang H, Wang J, Zhao H
Neuroscience letters 2025 Nov 1;867:138369
Neuroscience letters 2025 Nov 1;867:138369
Naringenin targets and inhibits Monoamine Oxidase A/B to bidirectionally regulate intestinal motility.
Li Q, Chen Y, Zhang Y, Xu C, Tang T, Qian Y, Seng OS, Wang Y, Fang L, Xu T
Chemico-biological interactions 2025 Nov 1;421:111742
Chemico-biological interactions 2025 Nov 1;421:111742
Bioinformatics and validation reveal spinal cord cathepsin S potential degradation of perineuronal nets in neuropathic pain.
Pang J, Hu Z, Zhao Y, Liu X, Wang B, Fang Q, Xu Y, Hu Y, Zeng H, Wu W
Neuropharmacology 2025 Nov 1;278:110577
Neuropharmacology 2025 Nov 1;278:110577
Oxidative damage to lung mitochondrial DNA is a key contributor to the development of chemical lung injury.
Dubey S, Yu Z, Stephens EM, Lazrak A, Ahmad I, Aggarwal S, Andrabi S, Hossain MI, Jilling T, Fernandez SR, Bartels JL, Lapi SE, Mobley JA, Pastukh VM, Gillespie MN, Matalon S
Redox biology 2025 May;82:103624
Redox biology 2025 May;82:103624
Circulating Mitochondrial N-Formyl Peptides Are Associated with Acute Respiratory Distress Syndrome after Cardiopulmonary Bypass and Regulate Endothelial Barrier through FPR2.
Lu P, Li X, Wang J, Li X, Shen Z, Qi Y, Chu M, Yao X, Zhang X, Zheng Y, Zhan F, Song M, Wang X
American journal of respiratory cell and molecular biology 2025 May;72(5):533-550
American journal of respiratory cell and molecular biology 2025 May;72(5):533-550
Vitamins D and K jointly protect against osteoarthritis via regulating OSCAR during osteoclastogenesis.
Zhao Y, Ou Q, Huang H, Li D, Chen J, Xue S, Zhou Z, Ruan G, Ding C
Journal of orthopaedic translation 2025 May;52:387-403
Journal of orthopaedic translation 2025 May;52:387-403
Regulation of N-Glycosylation of CDNF on Its Protein Stability and Function in Hypoxia/Reoxygenation Model of H9C2 Cells.
Huang Q, Dong H, Jia W, Ren Y, Li W, Zhong L, Gong L, Yang J
Cell biology international 2025 May;49(5):472-483
Cell biology international 2025 May;49(5):472-483
Cyclic RGD modified dextran-quercetin polymer micelles for targeted therapy of breast cancer.
Yang C, Ma H, Liang Z, Zhuang Y, Hu L, Zhang K, Huang L, Li M, Zhang S, Zhen Y
International journal of biological macromolecules 2025 May;308(Pt 1):142272
International journal of biological macromolecules 2025 May;308(Pt 1):142272
Histone acetyltransferase BmMOF inhibits the proliferation of the Bombyx mori nucleopolyhedrovirus by targeting Bmp53.
Miao M, Bai SM, Huang YY, Zhang JW, Xu KL, Chen Y, Qian QT, Dong J, Nie HM, Mei J, Tong FD, Yu W
International journal of biological macromolecules 2025 May;305(Pt 2):141186
International journal of biological macromolecules 2025 May;305(Pt 2):141186
De Novo Protein Synthesis Occurs Through the Cytoplasmic Translation Machinery in Mammalian Spermatozoa.
Corda PO, Silva JV, Almeida CR, Pierre P, Fardilha M
Journal of cellular physiology 2025 May;240(5):e70038
Journal of cellular physiology 2025 May;240(5):e70038
Pad2 deletion induces anxiety‑like behaviors and memory deficits in mice.
Lv X, Deng H, Li C, Gao W, Zhang Y, Gao Y, Zhao B, Shi C, Gao J, Liu Z
Brain research bulletin 2025 May;224:111327
Brain research bulletin 2025 May;224:111327
Distinct In Vitro Differentiation Protocols Differentially Affect Cytotoxicity Induced by Heavy Metals in Human Neuroblastoma SH-SY5Y Cells.
Ferdous J, Naitou K, Shiraishi M
Biological trace element research 2025 May;203(5):2595-2605
Biological trace element research 2025 May;203(5):2595-2605
Myd88 functions as a negative regulator of IRF11-mediated IFN production in teleosts.
Xiang C, Li W, Zhou X, Li D, Huang W, Nie P, Huang B
Developmental and comparative immunology 2025 May;167:105388
Developmental and comparative immunology 2025 May;167:105388
Sauchinone preserves cardiac function in doxorubicin-induced cardiomyopathy by inhibiting the NLRP3 inflammasome.
Xin W, Yang H, Heng X, Xu T, Zhang K, Zhao Y, Liu Y, Han D, Wu Y, Zhang W, He M, Pu L, Shen Y, Qu X, Sun N, Ye C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156624
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156624
Identification and Functional Analysis of Novel Mutations in AXIN2 and LRP6 Linked With Non-Syndromic Tooth Agenesis.
Luo W, Yue H, Song G, Cheng J, He M
Molecular genetics & genomic medicine 2025 May;13(5):e70101
Molecular genetics & genomic medicine 2025 May;13(5):e70101
LMTK2 and CRB1 are two novel risk genes for Alzheimer's disease in Han Chinese.
Xiao X, Liu H, Yao R, Li Y, Liao X, Liu Y, Zhou Y, Wang J, Tang B, Jiao B, Li J, Shen L, Luo S
The journal of prevention of Alzheimer's disease 2025 May;12(5):100087
The journal of prevention of Alzheimer's disease 2025 May;12(5):100087
MARVELD1 inhibits Neuro2a cell migration and tumorigenesis via regulating the transcriptional coactivators and protein methylation.
Liu W, Dong Y, Guo R, Zhou D, Qin Y, Ma Y, Zhang J, Li A
Bulletin du cancer 2025 May;112(5):458-468
Bulletin du cancer 2025 May;112(5):458-468
Inactivation of TACC2 epigenetically represses CDKN1A and confers sensitivity to CDK inhibitors.
Lin ZR, Xia TL, Wang MY, Zhang LJ, Liu YM, Yuan BY, Zhou AJ, Yuan L, Zheng J, Bei JX, Lin DX, Zeng MS, Zhong Q
Med (New York, N.Y.) 2025 May 9;6(5):100568
Med (New York, N.Y.) 2025 May 9;6(5):100568
A Novel Role of Adipokine 'Intelectin-1': Ameliorating Renal Fibrosis Through Inhibition of Renal Tubular Epithelial Cell Senescence.
Zhang Y, Shen M, Zhang B, Li X, Cheng H, Feng D, Han Y, Luo Z, Zhou Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70653
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70653
Multi-parameter magnetic resonance imaging of zebularine in liver fibrosis treatment and calcineurin/NFAT3 mechanism.
Lyu SY, Xiao W, Chen YJ, Liao QL, Cai YY, Yu C, Liu JY, Liu H, Zhang MP, Ren YL, Yu QL, Qi YM, Xiao EH, Luo YH
World journal of gastroenterology 2025 May 28;31(20):105554
World journal of gastroenterology 2025 May 28;31(20):105554
Complement C4 exacerbates astrocyte-mediated neuroinflammation and promotes α-synuclein pathology in Parkinson's disease.
Zou W, Kou L, Wang Y, Jin Z, Xiong N, Wang T, Xia Y
NPJ Parkinson's disease 2025 May 28;11(1):141
NPJ Parkinson's disease 2025 May 28;11(1):141
The Therapeutic Potential of Bombyx Batryticatus for Chronic Atrophic Gastritis Precancerous Lesions via the PI3K/AKT/mTOR Pathway Based on Network Pharmacology of Blood-Entering Components.
Wang X, Chang M, Feng K, Wang Q, Li B, Gao W
Pharmaceuticals (Basel, Switzerland) 2025 May 25;18(6)
Pharmaceuticals (Basel, Switzerland) 2025 May 25;18(6)
Targeting of the IL-33/Wnt axis restricts breast cancer stemness and metastasis.
Fan G, Zuo S, Wang Z, Zhang S, Liu L, Luo H, Xie Y, Zhang Y, Li D
Scientific reports 2025 May 25;15(1):18172
Scientific reports 2025 May 25;15(1):18172
TREM2 deficiency exacerbates cognitive impairment by aggravating α-Synuclein-induced lysosomal dysfunction in Parkinson's disease.
Zhu B, Feng J, Liang X, Fu Z, Liao M, Deng T, Wang K, Xie J, Chi J, Yang L, Gao Y, Nie K, Wang L, Zhang P, Zhang Y
Cell death discovery 2025 May 20;11(1):243
Cell death discovery 2025 May 20;11(1):243
ZLN005, a PGC-1α agonist, delays photoreceptor degeneration by enhancing mitochondrial biogenesis in a murine model of retinitis pigmentosa.
Hu C, Ren C, Wu Y, Lin R, Shen T, Li T, Yu D, Jiang L, Wan Z, Luo Y, Su T, Yu J, Qiu Y
Neuropharmacology 2025 May 15;269:110361
Neuropharmacology 2025 May 15;269:110361
PAI-1-driven SFRP2(high) cancer-associated fibroblasts hijack the abscopal effect of radioimmunotherapy.
Zhang YP, Guo ZQ, Cai XT, Rong ZX, Fang Y, Chen JQ, Zhuang KM, Ruan MJ, Ma SC, Lin LY, Han DD, Li YS, Wang YY, Wang J, Cao CH, Tang XR, Xie QK, Chen Y, Lin Y, Tan JL, Yu ZH, Wu ZN, Wei W, Zheng DY, Zeng YJ, Ruan YC, Xu ZP, Gu JZ, Xiao LS, Liu L, Guan J, Bai X, Wu DH, Dong ZY
Cancer cell 2025 May 12;43(5):856-874.e9
Cancer cell 2025 May 12;43(5):856-874.e9
HBV core protein enhances WDR46 stabilization to upregulate NUSAP1 and promote HCC progression.
Kong F, Bao E, Zhong Y, Wang Y, Liu R, Zhang H, Yang L, Jiang R, Liu X, Li C, Liu X, Pan X, Zheng K, You H, Tang R
Hepatology communications 2025 May 1;9(5)
Hepatology communications 2025 May 1;9(5)
Distinct Transcriptomic Profiles of Cultured Anterior and Posterior Populations of Human Infant Scleral Fibroblasts: Including Dopamine Receptors.
Guan J, Hong G, Liu Z, Zheng Y, He J, Qin D, Li H
Investigative ophthalmology & visual science 2025 May 1;66(5):29
Investigative ophthalmology & visual science 2025 May 1;66(5):29
Inhibition of microRNA-139-5p by glucagon-like peptide-1 ameliorates oxidative stress-induced vascular endothelial cell damage via targeting SOD1/GCLc.
Zhang J, Mo J, Liu Y, Meng X, Tang W, Fu L, Xiong J, Mo Z
Endocrine connections 2025 May 1;14(5)
Endocrine connections 2025 May 1;14(5)
Computational and functional prioritization identifies genes that rescue behavior and reduce tau protein in fly and human cell models of Alzheimer disease.
Stephens MC, Li J, Mair M, Moore J, Zhu K, Tarkunde A, Amoh B, Perez AM, Bhakare A, Guo F, Shulman JM, Al-Ramahi I, Botas J
American journal of human genetics 2025 May 1;112(5):1081-1096
American journal of human genetics 2025 May 1;112(5):1081-1096
Lentinan alleviates cadmium-induced kidney injury by reducing cadmium accumulation via promoting cadmium excretion and metallothionein synthesis and regulating silencing information regulator1/nuclear factor erythroid 2-related factor 2/nuclear factor kappa-B signaling pathway.
Wang X, Zhao G, Zhao Q, Hu M, Wang Y, Li Q, Wang S, Qiao M, Shen Y, Li N, Huang X, Wang D, Gan RY, Song L
Journal of food science 2025 Mar;90(3):e70163
Journal of food science 2025 Mar;90(3):e70163
Mitochondrial-Derived Signaling Mediates Differentiation of Parietal Epithelial Cells into Podocytes.
Wang M, Wu W, Lu J, Lu R, Min L, Song A, Zhao B, Li Y, Xie K, Gu L
Antioxidants & redox signaling 2025 Mar;42(7-9):393-407
Antioxidants & redox signaling 2025 Mar;42(7-9):393-407
Study on metabolic disorders in rat liver induced by different times after scalds.
Chen Z, Lin H, Su X, Xu W, Fang W, Ruan G, Wang Z, Xu G, Pang R
Biochemistry and biophysics reports 2025 Mar;41:101904
Biochemistry and biophysics reports 2025 Mar;41:101904
Astragaloside IV Relieves Central Sensitization by Regulating Astrocytic ROS/NF-κB Nuclear Translocation Signaling in Chronic Migraine Male Rats.
Zhang W, Yang Y, Zhang X, Zhao L, Zhou J, Ji L, Chen L
Phytotherapy research : PTR 2025 Mar;39(3):1438-1452
Phytotherapy research : PTR 2025 Mar;39(3):1438-1452
GIMAP1 interacts with TMX1 to improve lung adenocarcinoma prognosis by influencing tumor immune microenvironment.
Ruan P, Li J, Abdelhalim KA, Tang Z, Tan W, Yao J, Tan Y, Wang L
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167661
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167661
KEAP1-NRF2/HO-1 Pathway Promotes Ferroptosis and Neuronal Injury in Schizophrenia.
Zhu F, Dan T, Hua S
Brain and behavior 2025 Mar;15(3):e70311
Brain and behavior 2025 Mar;15(3):e70311
Allium Macrostemon Bge. Attenuates the Cognitive Decline of Aging Mice by Enhancing BDNF/TrkB Pathway.
Sheng R, Zhao M, Pu K, Zhou Y, Zeng L, Chen Y, Wang P, Liu X, Xu S
Food science & nutrition 2025 Mar;13(3):e70010
Food science & nutrition 2025 Mar;13(3):e70010
ANXA2 promotes chondrocyte differentiation and fracture healing by regulating the phosphorylation of STAT3 and PI3K/AKT signaling pathways.
Wang X, Dong W, Wang X, Wang J
Cellular signalling 2025 Mar;127:111617
Cellular signalling 2025 Mar;127:111617
Semaglutide, a glucagon-like peptide-1 receptor agonist, inhibits oral squamous cell carcinoma growth through P38 MAPK signaling pathway.
Wang C, Wu Z, Zhou J, Cheng B, Huang Y
Journal of cancer research and clinical oncology 2025 Mar 7;151(3):103
Journal of cancer research and clinical oncology 2025 Mar 7;151(3):103
Inhibiting HMGB1/AGER/NF-κB pathway prevents pro-inflammatory microglia polarization and protect photoreceptors in retinitis pigmentosa.
Hu C, Cui T, Xu Z, Yang K, Wu Y, Cai W, Yu J, Qiu Y
International immunopharmacology 2025 Mar 6;149:114192
International immunopharmacology 2025 Mar 6;149:114192
Lactate Dehydrogenase A Crotonylation and Mono-Ubiquitination Maintains Vascular Smooth Muscle Cell Growth and Migration and Promotes Neointima Hyperplasia.
Chen ZH, Cao SH, Ren ZY, Zhang T, Jiang HM, Hu ZK, Dong LH
Journal of the American Heart Association 2025 Mar 4;14(5):e036377
Journal of the American Heart Association 2025 Mar 4;14(5):e036377
Uric acid promotes aortic valve calcification via mediating valve interstitial cell osteogenic differentiation and endothelial dysfunction.
Zhang J, Lei W, Zhou J, Zhang Y, Huang F, Chen M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Mar 31;39(6):e70437
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Mar 31;39(6):e70437
Arsenic enhances cervical cancer cell radiosensitivity by suppressing the DNA damage repair pathway.
Gao X, Liu G, Zhao Z, Tang Y, Hui H, Wang C, Li D, Ma Y, Sun Z, Zhou Y
Translational cancer research 2025 Mar 30;14(3):2078-2094
Translational cancer research 2025 Mar 30;14(3):2078-2094
Neurotransmitter 5-HT Further Promotes LL-37-Induced Rosacea-like Inflammation Through HTR3A.
Ma H, Liu J, Chen F, Zhou Y, Yang C, Zhao B
International journal of molecular sciences 2025 Mar 28;26(7)
International journal of molecular sciences 2025 Mar 28;26(7)
Mitochondrial miRNA miR-134-5p Play Oncogenic Role in Clear Cell Renal Cell Carcinoma.
Shen T, Wang W, Wang H, Zhu X, Zhu G
Biomolecules 2025 Mar 20;15(3)
Biomolecules 2025 Mar 20;15(3)
S1PR3 in hippocampal neurons improves synaptic plasticity and decreases depressive behavior via downregulation of RhoA/ROCK1.
Liu H, Chen S, Xiang H, Xiao J, Zhao S, Zhang X, Shu Z, Zhang J, Ouyang J, Liu Q, Quan Q, Fan J, Gao P, Zheng X, Chen AF, Lu H
Progress in neuro-psychopharmacology & biological psychiatry 2025 Mar 20;137:111256
Progress in neuro-psychopharmacology & biological psychiatry 2025 Mar 20;137:111256
IFI16 recruits HDAC1 and HDAC2 to deacetylate the Kaposi's sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen (LANA), facilitating latency.
Ghosh A, Britto J, Chandran B, Roy A
Journal of virology 2025 Mar 18;99(3):e0154924
Journal of virology 2025 Mar 18;99(3):e0154924
Neuroprotective effect of apo-9'-fucoxanthinone against cerebral ischemia injury by targeting the PI3K/AKT/GSK-3β pathway.
Qi Y, Tang S, Jin S, Wang J, Zhang Y, Xu X, Zhu H, Zhang J, Xu X, Zhao M, Zhu H, Yan P
European journal of pharmacology 2025 Mar 15;991:177348
European journal of pharmacology 2025 Mar 15;991:177348
Mitochondrial Calcium Uniporter knockdown improves the viability of HT22 hippocampal neurons in Alzheimer's disease.
Cai H, Hou F, Wang Y, Wu L, Wang Z, Wu M, Wang X, Hölscher C
European journal of pharmacology 2025 Mar 15;991:177347
European journal of pharmacology 2025 Mar 15;991:177347
Polo-like kinase2 regulates renal tubulointerstitial fibrosis via notch signaling pathway in diabetic kidney disease.
Luo J, Xu H, Su C, Dong W, Xiao M, Xiao N, Jia Y, Xue Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Mar 15;39(5):e70455
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Mar 15;39(5):e70455
YTHDC1 negatively regulates UBE3A to influence RAD51 ubiquitination and inhibit apoptosis in colorectal cancer cells.
Gao M, Wu Y, Zhang L, Zhou Y, Liu H, Zhang W, Wang S, Cui Y
Scientific reports 2025 Mar 14;15(1):8857
Scientific reports 2025 Mar 14;15(1):8857
Design of Selective BRD4 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease.
Yang Y, Liu H, Yuan H, Lyu K, Zhong H, Li Y, Cao D, Zhao W, Zhang H, Xiong B, Chen D, Guo D
Journal of medicinal chemistry 2025 Mar 13;68(5):5257-5274
Journal of medicinal chemistry 2025 Mar 13;68(5):5257-5274
Blueberry Anthocyanin Extracts (BAEs) Protect Retinal and Retinal Pigment Epithelium Function from High-Glucose-Induced Apoptosis by Activating GLP-1R/Akt Signaling.
Li R, Du S, Ye Z, Yang W, Liu Y
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5886-5898
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5886-5898
Intrinsic differences in mTOR activity mediates lineage-specific responses to cyclophosphamide in mouse and human granulosa cells.
Xu S, Ma Y, Zhang Y, Ying H, Tong X, Yang W, Pan Y, Rong Y, Dai Y, Zhang S, Han P
Journal of ovarian research 2025 Mar 11;18(1):49
Journal of ovarian research 2025 Mar 11;18(1):49
Prognostic implications and characterization of tumor-associated tertiary lymphoid structures genes in pancreatic cancer.
Zhang E, Ma Y, Liu Z, Zhang J, Liu W, Chen Y, Liu G, Liu X, Zhang F, Zhu Y, Yang Y, Tian X
Journal of translational medicine 2025 Mar 10;23(1):301
Journal of translational medicine 2025 Mar 10;23(1):301
LINC02154 Promotes Esophageal Squamous Cell Carcinoma Progression via the PI3K-AKT-mTOR Signaling Pathway by Interacting With IGF2BP2.
Zhang M, Zhang C, Zhou F, Yang R, Feng Y, Ji Y, Ren H, Ming L
Molecular carcinogenesis 2025 Jun;64(6):985-996
Molecular carcinogenesis 2025 Jun;64(6):985-996
H3K18 lactylation-mediated SIX1 upregulation contributes to silica-induced epithelial-mesenchymal transition in airway epithelial cells.
Liu S, He Y, Jin L, Shi S, Zhang J, Xie W, Yang M, Zhang Q, Kong H
Toxicology 2025 Jun;514:154109
Toxicology 2025 Jun;514:154109
Crosstalk Between Th17 Cells and Renal Tubular Epithelial Cells Promotes Fibrotic Progression in IgA Nephropathy.
Zhou YN, Xia JK, Shi CR, He Y, Shang SL
Current medical science 2025 Jun;45(3):626-639
Current medical science 2025 Jun;45(3):626-639
K(+)-H(+) coupling strategy for immune regulation and bone defect repair.
Hu L, Yang K, Chen Y, Wang H, Fu Z, Jiang L, Xu J, Tian H, Zhu Y, Dai Z, Li Y, Chen X, Lin X, Chen P, Gu C, Fan S
Materials today. Bio 2025 Jun;32:101744
Materials today. Bio 2025 Jun;32:101744
Cryo-trojan mesenchymal stem cells as non-living tumor-homing supercarriers for enhanced drug delivery and immune activation in prostate cancer.
Wang C, Rong X, Zhang F, Mu X, Jiang J
Materials today. Bio 2025 Jun;32:101650
Materials today. Bio 2025 Jun;32:101650
Transcriptome profiling reveals that the host BRD4 protein facilitates African swine fever virus infection and suppresses inflammatory cytokine expression by downregulating transcriptional regulatory signaling pathways.
Wu M, Yang J, Tian Z, Sun H, Zhang Z, Luo J, Guan G, Yin H, Niu Q, Hao R
Veterinary microbiology 2025 Jun;305:110498
Veterinary microbiology 2025 Jun;305:110498
Melatonin attenuates inflammatory bone loss by alleviating mitophagy and lactate production.
Lin Z, Gu Y, Liu Y, Chen Z, Fang S, Wang Z, Liu Z, Lin Q, Hu Y, Jiang N, Yu B, Liu G
Apoptosis : an international journal on programmed cell death 2025 Jun;30(5-6):1351-1371
Apoptosis : an international journal on programmed cell death 2025 Jun;30(5-6):1351-1371
HDAC9 Deficiency Upregulates cGMP-dependent Kinase II to Mitigate Neuronal Apoptosis in Ischemic Stroke.
Lin H, Bei Y, Shen Z, Wei T, Ge Y, Yu L, Xu H, He W, Dai Y, Yao D, Dai H
Translational stroke research 2025 Jun;16(3):868-881
Translational stroke research 2025 Jun;16(3):868-881
An Energy Metabolism Nanoblocker for Cutting Tumor Cell Respiration and Inhibiting Mitochondrial Hijacking from Cytotoxic T Lymphocyte.
Leng X, Yang Y, Jiang T, Zheng J, Zhang L, Huang J, Xu H, Fang M, Li X, Wang Z, Ge M, Lin H
Advanced healthcare materials 2025 Jun;14(16):e2405174
Advanced healthcare materials 2025 Jun;14(16):e2405174
Vegfr3 activation of Pkd2l1(+) CSF-cNs triggers the neural stem cell response in spinal cord injury.
Cao L, Shangguan Z, Zhang Y, Luo Z, Chen C, Yan H, Fu X, Tan W, Wang C, Dou X, Zheng C, Li Q
Cellular signalling 2025 Jun;130:111675
Cellular signalling 2025 Jun;130:111675
A Novel Theranostic Strategy for Malignant Pulmonary Nodules by Targeted CECAM6 with (89)Zr/(131)I-Labeled Tinurilimab.
Chen C, Zhu K, Wang J, Pan D, Wang X, Xu Y, Yan J, Wang L, Yang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415689
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415689
Knockdown of RUNX2 Attenuated A1 Astrocyte Overactivation, Brain Injury, and Cerebral Edema During Ischemic Stroke.
Ai Z, Huang W, Hu W, An R, Lei G, Gu W, Peng X, Liu Y
Neuromolecular medicine 2025 Jun 27;27(1):48
Neuromolecular medicine 2025 Jun 27;27(1):48
VIRMA-mediated m(6)A modification regulates forebrain formation through modulating ribosome biogenesis.
Wu M, Wu X, Sun H, Wang W, Zhang L, Liu X, Zhang Y, Zhang X, Liu J, Shen B, Zhou T
Science advances 2025 Jun 27;11(26):eadq9643
Science advances 2025 Jun 27;11(26):eadq9643
Peptide Hydrogels for Renal Carcinoma Therapy via Synergistic Inhibition of Glycolysis and Mitochondrial Metabolism Reprogramming.
Ge Z, Xu J, Meng F, Sun M, He L, Fan Z, Du J
ACS applied materials & interfaces 2025 Jun 25;17(25):36487-36496
ACS applied materials & interfaces 2025 Jun 25;17(25):36487-36496
STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma.
Yu W, Gui S, Peng L, Luo H, Xie J, Xiao J, Yilamu Y, Sun Y, Cai S, Cheng Z, Tao Z
Developmental cell 2025 Jun 23;60(12):1751-1767.e9
Developmental cell 2025 Jun 23;60(12):1751-1767.e9
Yinchenhao Decoction Mitigates Cholestatic Liver Injury in Mice via Gut Microbiota Regulation and Activation of FXR-FGF15 Pathway.
Li W, Huang D, Luo Z, Zhou T, Jin Z
Pharmaceuticals (Basel, Switzerland) 2025 Jun 20;18(7)
Pharmaceuticals (Basel, Switzerland) 2025 Jun 20;18(7)
Excretory/secretory products from Hymenolepis nana adult worms alleviate ulcerative colitis in mice via tuft/IL-13 signaling pathway.
Mou R, Cui X, Wang H, Zhang Z, Cheng Y, Wu W, Li J, Zhang K
Parasites & vectors 2025 Jun 20;18(1):230
Parasites & vectors 2025 Jun 20;18(1):230
Pretreatment with Citrus reticulata 'Chachi' Polysaccharide Alleviates Alcohol-Induced Gastric Ulcer by Inhibiting NLRP3/ASC/Caspase-1 and Nrf2/HO-1 Signaling Pathways.
Liang H, Liang Y, Wu L, Lin L, Yao Y, Deng J, Xu J, Li H, Gao F, Xing W, Yu M, Jia X, Wei M, Li C, Zheng G
Nutrients 2025 Jun 20;17(13)
Nutrients 2025 Jun 20;17(13)
Long Non-Coding RNA LOC401312 Induces Radiosensitivity Through Upregulation of CPS1 in Non-Small Cell Lung Cancer.
Cao Z, Wang T, Tai F, Zhai R, Li H, Li J, Xiang S, Gao H, Zheng X, Li C
International journal of molecular sciences 2025 Jun 19;26(12)
International journal of molecular sciences 2025 Jun 19;26(12)
Sleep deficiency exacerbates periodontal inflammation via trigeminal TRPV1 neurons.
Li J, Cui Z, Gong H, Zhang Y, Yuan Z, Zhang Z, Ma Z, Zhou N, Huang C, Zhao Y, Li X, Zhang Z, Sun Y
Proceedings of the National Academy of Sciences of the United States of America 2025 Jun 17;122(24):e2424169122
Proceedings of the National Academy of Sciences of the United States of America 2025 Jun 17;122(24):e2424169122
The Effect of FPR2 on the Regulation of Trophoblast Autophagy via the PI3K/AKT/mTOR Signaling Pathway in Preeclampsia.
Jiang N, Zhou M, Le Y, Xiao L, Zhang C, Li S, Guo J, Wu Y, Zhang M, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70697
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70697
Direct Peritoneal Resuscitation and Melatonin in the Treatment of Abdominal Sepsis-Induced Lung Injury via Macrophage Metabolic Reprogramming.
Zhao Z, Ji J, Ming L, Luo Z, Li M, Chen Y, Sun R, Lu W, Tian W, Yang F, Huang Q
Journal of pineal research 2025 Jul;77(4):e70066
Journal of pineal research 2025 Jul;77(4):e70066
Silencing YTHDF2 Induces Apoptosis of Neuroblastoma Cells In a Cell Line-Dependent Manner via Regulating the Expression of DLK1.
Hua Z, Gong B, Li Z
Molecular neurobiology 2025 Jul;62(7):8121-8134
Molecular neurobiology 2025 Jul;62(7):8121-8134
Gastrodin alleviates Aβ(25-35)-induced glycolytic dysfunction via activating PI3K/AKT/BACH1 signaling in Alzheimer's disease models.
Liu TT, Yang X, Lei HP, Hu YT, Wu LN, Wei AH, Ji XH, Liu J, Jin H, Shi JS, Zhou SY, Jin F
Experimental neurology 2025 Jul;389:115225
Experimental neurology 2025 Jul;389:115225
Chronic prostatitis/chronic pelvic pain syndrome impairs erectile function by inducing apoptosis in a rat model of experimental autoimmune prostatitis.
Gu Q, Luan J, Yu M, Xia J, Wang Z
International journal of impotence research 2025 Jul;37(7):519-526
International journal of impotence research 2025 Jul;37(7):519-526
CircSETD3 interrupts the bidirectional positive feedback of ErbB3 and Akt by sponging miR-4667-5p to inhibit colorectal cancer progression and cetuximab resistance.
Li X, Chen T, Cai Y, Zhang J, Wang Y, Wang J, Mao X, Xu L, Li D, Wang Y, Wang X
International journal of biological macromolecules 2025 Jul;318(Pt 4):145352
International journal of biological macromolecules 2025 Jul;318(Pt 4):145352
AD16 Modulates Microglial Activation and Polarization to Mitigate Neuroinflammation in Ischemic Stroke Models Through α7nAChR-ERK-STAT3 Signaling.
Zhao GJ, Zhang LM, Wang SR, Yang M, Jiang JH, Yuan BX, Huang C, Huang ZH, Tang XL, Chen T
CNS neuroscience & therapeutics 2025 Jul;31(7):e70519
CNS neuroscience & therapeutics 2025 Jul;31(7):e70519
Phellodendrine chloride alleviates gouty arthritis through IL-6/STAT3 signaling pathway.
Qin YY, Qin ZY, Liang T, Qin DE, Hua SY, Tan MH, Guo S, Yang F, Shi L, Yu Y, Zhang GJ
Immunobiology 2025 Jul;230(4):152918
Immunobiology 2025 Jul;230(4):152918
Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration.
Tang Q, Tang K, Markby GR, Parys M, Phadwal K, MacRae VE, Corcoran BM
Autophagy 2025 Jul;21(7):1433-1455
Autophagy 2025 Jul;21(7):1433-1455
Design, synthesis, and antitumor activity of novel thioheterocyclic nucleoside derivatives by suppressing the c-MYC pathway.
Li XJ, Huang KX, Wang KX, Liu R, Wang DC, Liang YR, Hao EJ, Wang Y, Guo HM
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3685-3707
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3685-3707
AdipoR2 enhances adipocyte thermogenesis in Tibetan pigs via AMPK-ACC signaling.
Liu S, Yang Z, Yang Y, Cai Y, Zhao S
Journal of thermal biology 2025 Jul;131:104209
Journal of thermal biology 2025 Jul;131:104209
STAT1 and STAT6 orchestrate Cbs transcription and transsulfur metabolism in microglia and contribute to parkinson's disease-related neuroinflammation.
Liu Y, Wang Z, Ma YT, Chen YX, Qian XY, Hou XO, Wan B, Ren HG, Hu LF
Cellular and molecular life sciences : CMLS 2025 Jul 30;82(1):294
Cellular and molecular life sciences : CMLS 2025 Jul 30;82(1):294
TSPAN7 inhibits pancreatic cancer progression by suppressing DNA double-strand break repair and enhances sensitivity to immunochemotherapy.
Lin H, Zhou J, Li Y, Luo L, Zeng Y, Liang X, Yu J, Ye C, Yang P, Lin Y, Li Y, Zeng L
Biochemical pharmacology 2025 Jul 30;242(Pt 1):117199
Biochemical pharmacology 2025 Jul 30;242(Pt 1):117199
HOXC4 promotes proliferation of endometriotic stromal cells via the SLIT2-ROBO1 axis.
Yang Y, Yin B, Li C, Dong X, Wang M, Su J, Tang X, Chen R, Li Q, Ding D
Molecular human reproduction 2025 Jul 3;31(3)
Molecular human reproduction 2025 Jul 3;31(3)
Protocatechuic acid suppresses ferroptosis to protect against hypoxic-ischemic encephalopathy by targeting the HIF-1α/VEGFA axis.
Zhang X, Luo J, Bharati L, Hua Z, Chen S, Dong Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156900
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156900
Discovery of 2-Pyrazolylpyrimidinone Derivatives as New SPOP Inhibitors for Renal Cell Carcinoma Therapy.
Zhang Q, Zhou Y, Zhao J, Hu L, Zhu Z, Wang H, Jin Y, You Q, Jiang Z, Guo X
Journal of medicinal chemistry 2025 Jul 24;68(14):14945-14961
Journal of medicinal chemistry 2025 Jul 24;68(14):14945-14961
Kai-Xin-San ameliorates fluoxetine-resistant depressive-like behaviors by modulating tryptophan-kynurenine metabolic homeostasis in a rodent model.
Yao L, Jing R, Wang C, Wang Y, Li X, Wu X, Wang Y, Liu L, Mu L, Liu P, Hu Y
Journal of ethnopharmacology 2025 Jul 24;351:120011
Journal of ethnopharmacology 2025 Jul 24;351:120011
TRIB3 regulates Cx43 expression in human granulosa cells via the Wnt/β-catenin signaling pathway: an in vitro study.
Zhu Z, Dong J, Liu W, Xia L, Niu Z
Journal of ovarian research 2025 Jul 2;18(1):139
Journal of ovarian research 2025 Jul 2;18(1):139
Design, synthesis and biological evaluation of novel β-caryophyllene derivatives as potential anti-cancer agents through the ROS-mediated apoptosis pathway.
Wang Z, Chen Y, Huang A, Wen H, Wu Y, Xu X, Qiao Z, Chen L, Zhao Y, Liang X
RSC medicinal chemistry 2025 Jul 16;16(7):3174-3189
RSC medicinal chemistry 2025 Jul 16;16(7):3174-3189
TBB inhibits CK2/PD-L1/EGFR pathway-mediated tumor progression.
Che S, Zhang Y, Xu H, Shi J, Hou Y
European journal of pharmacology 2025 Jul 15;999:177689
European journal of pharmacology 2025 Jul 15;999:177689
CLDN4 palmitoylation promotes hepatic-to-biliary lineage transition and lenvatinib resistance in hepatocellular carcinoma.
Xu M, Zheng Y, Chen J, Gao C, Zhu M, Ma A, Liang B, Xu W, Fan J, Zhou H, Ke A, Shen Y
Cell reports. Medicine 2025 Jul 15;6(7):102208
Cell reports. Medicine 2025 Jul 15;6(7):102208
The interaction between COX-2 and endoplasmic reticulum stress is involved in liver ischemia-reperfusion injury in mice.
Liang C, Guo L, Tian X, Mu Z, Chen M, Hu Y, Su J
Molecular biology reports 2025 Jul 15;52(1):710
Molecular biology reports 2025 Jul 15;52(1):710
SIRT5 alleviates oxidative stress of boar sperm induced by cryopreservation through IDH2 and SOD2 pathway.
Ali MA, Zhang Y, Ni Q, Huang AQ, Dou S, Tang Y, Xu X, Zeng C
Theriogenology 2025 Jul 15;241:117424
Theriogenology 2025 Jul 15;241:117424
Gut bacteria and the host synergies promote resveratrol metabolism and induce tolerance in ALD mice.
Zhang SX, Hu FF, Chen H, Guo J, Xiang ZW, Ding X, Ye ML, Ye WL, Chen JH, Wang X, Han WJ, Zhou HH, Zhang W, Huang Y, Wu LL, Lian GH, Chen Y
NPJ biofilms and microbiomes 2025 Jul 14;11(1):132
NPJ biofilms and microbiomes 2025 Jul 14;11(1):132
Tang Bi formula alleviates diabetic sciatic neuropathy via AMPK/PGC-1α/MFN2 pathway activation.
Yang C, Yu H, Zhou L, Su H, Li X, Qi W, Lian F
Scientific reports 2025 Jul 11;15(1):25069
Scientific reports 2025 Jul 11;15(1):25069
Pharmacological evaluation of physcion as a TRPV1 inhibitor with multimodal analgesic efficacy in experimental pain models.
Chen H, Li G, Deng L, Li S, Huang S, Lee SM, Nie X, Bian JS
Biological research 2025 Jul 10;58(1):48
Biological research 2025 Jul 10;58(1):48
Differences in macrophage pyroptosis and polarization induced by nano-/micro-calcium oxalate crystals.
Tong XY, Nong WJ, Tan RM, Ouyang JM
Journal of nanobiotechnology 2025 Jul 10;23(1):499
Journal of nanobiotechnology 2025 Jul 10;23(1):499
Intermediate filament IFFO1 negatively regulates the migration of lung cancer cells by inhibiting the IQGAP3-Cdc42 interaction.
Ye Y, Shen F, Yan M, Zhan C, Lv J, Zou M, Wang Z, Ning S, Gao Y, Wu J, Li W
Cell death & disease 2025 Jul 10;16(1):509
Cell death & disease 2025 Jul 10;16(1):509
Consensus artificial intelligence-driven prognostic signature for predicting the prognosis of hepatocellular carcinoma: a multi-center and large-scale study.
Wen W, Wang R
NPJ precision oncology 2025 Jul 1;9(1):207
NPJ precision oncology 2025 Jul 1;9(1):207
Self-propelled smart nanomotors for enhanced mild photothermal therapy of tumors through autophagy modulation.
Mei L, Liu H, Ding Q, Xie Y, Shen X, Chen H, Wang K, Li M, He Q
Acta biomaterialia 2025 Jul 1;201:574-590
Acta biomaterialia 2025 Jul 1;201:574-590
BSCL2 and CDK5 are two genes associated with circadian rhythm disturbance in Parkinson's disease.
Chen D, Huang Q, Ye M
Scientific reports 2025 Jul 1;15(1):22096
Scientific reports 2025 Jul 1;15(1):22096
Identification of a ferroptosis related genes signature and GDF15 contributing to a new perspective for the diagnosis of CRPC.
Shao Y, Li X, Liu J, Qiu Z, Zhang T, Li N, Hu J, Lu F, Zhu Z
Scientific reports 2025 Jul 1;15(1):21624
Scientific reports 2025 Jul 1;15(1):21624
IL-17A's role in exacerbating radiation-induced lung injury: Autophagy impairment via the PP2A-mTOR pathway.
Liu L, Yi G, Li X, Chen C, Chen K, He H, Li J, Cai F, Peng Y, Yang Z, Zhang X
Biochimica et biophysica acta. Molecular cell research 2025 Jan;1872(1):119864
Biochimica et biophysica acta. Molecular cell research 2025 Jan;1872(1):119864
Impaired Iron-Sulfur Cluster Synthesis Induces Mitochondrial PARthanatos in Diabetic Cardiomyopathy.
Wang M, Zhang S, Tian J, Yang F, Chen H, Bai S, Kang J, Pang K, Huang J, Dong M, Dong S, Tian Z, Fang S, Fan H, Lu F, Yu B, Li S, Zhang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(1):e2406695
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(1):e2406695
GNF-5837 alleviates intervertebral disc ageing by upregulating glutathione peroxidase 7.
Xu Y, Chen R, Zhuang Y, Xu W
International journal of immunopathology and pharmacology 2025 Jan-Dec;39:3946320251343365
International journal of immunopathology and pharmacology 2025 Jan-Dec;39:3946320251343365
Diagnostic role of circulating long non-coding RNA LINC00312 in patients with non-small cell lung cancer: a retrospective study.
Zhang R, Jiang Y, Gu J, Zhang X, Xie Y
BMC cancer 2025 Jan 9;25(1):47
BMC cancer 2025 Jan 9;25(1):47
Cromolyn sodium reduces LPS-induced pulmonary fibrosis by inhibiting the EMT process enhanced by MC-derived IL-13.
Tan C, Zhou H, Xiong Q, Xian X, Liu Q, Zhang Z, Xu J, Yao H
Respiratory research 2025 Jan 6;26(1):3
Respiratory research 2025 Jan 6;26(1):3
Cordycepin Extracted from Cordyceps militaris mitigated CUMS-induced depression of rats via targeting GSK3β/β-catenin signaling pathway.
Wang Y, Deng Y, Feng M, Chen J, Zhong M, Han Z, Zhang Q, Sun Y
Journal of ethnopharmacology 2025 Jan 31;340:119249
Journal of ethnopharmacology 2025 Jan 31;340:119249
Elucidation of the mechanism of the Yinhua Miyanling Tablet against urinary tract infection based on a combined strategy of network pharmacology, multi-omics and molecular biology.
Zheng H, Yu X, Wang C, Guo X, Gao C, Chen K, Wang G, Lin H, Liu C, Liu J, Wang F
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118835
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118835
N(6)-methyladenosine in 28S rRNA promotes oncogenic mRNA translation and tyrosine catabolism.
Chen B, Li L, Huang Y, Ma J, Ji F, Chen Y, Wu L, Peng H
Cell reports 2025 Jan 28;44(1):115139
Cell reports 2025 Jan 28;44(1):115139
Adipose mesenchymal stem cell-derived extracellular vesicles alleviate renal fibrosis by reducing epithelial-mesenchymal transition via the FOXS1/Wnt/β-catenin signaling pathway.
Sun J, Jia Y, Chen S, Bian Y, Liang H, Du X
International immunopharmacology 2025 Jan 27;146:113880
International immunopharmacology 2025 Jan 27;146:113880
CFAP65 is essential for C2a projection integrity in axonemes: implications for organ-specific ciliary dysfunction and infertility.
Chen J, Ren C, Zhao S, Wu H, Wang J, Dong Y, Liu S, Pan Y, Xiao Z, Yang S, Zhang J, Liu M
Cellular and molecular life sciences : CMLS 2025 Jan 24;82(1):61
Cellular and molecular life sciences : CMLS 2025 Jan 24;82(1):61
SUMO-Specific Peptidase 5 Promotes Oesophageal Squamous Cell Carcinoma Growth through the NF-κB-SLC1A3 Axis.
Du C, Hu Y, Yang X, Zhang Z, Gu J, Zhang T, Wang R, Zhang S, Tan L, Yu G
Frontiers in bioscience (Landmark edition) 2025 Jan 22;30(1):27047
Frontiers in bioscience (Landmark edition) 2025 Jan 22;30(1):27047
DUX4-induced HSATII RNA accumulation drives protein aggregation impacting RNA processing pathways.
Arends T, Bennett SR, Tapscott SJ
bioRxiv : the preprint server for biology 2025 Jan 22;
bioRxiv : the preprint server for biology 2025 Jan 22;
1-methyl-tryptophan improves anxiety-like behavior in colitis mice by inhibiting neuroinflammation, promoting cell regeneration, and decreasing apoptosis.
Zhao LP, Tan LL, Xia YM, Ma XY, Li T, Zhou SY, Wu J, Li MA, Zhao WJ, Shen YQ
Clinical and experimental immunology 2025 Jan 21;219(1)
Clinical and experimental immunology 2025 Jan 21;219(1)
Two novel heterozygous HPDL variants in a Chinese family with a neurodevelopmental disorder with progressive spasticity and brain white matter abnormalities.
Ma Y, Li G, Li L, Zong J, Liu W, Zhang R, Liu S
Gene 2025 Jan 20;934:149018
Gene 2025 Jan 20;934:149018
Both 20S and 19S proteasome components are essential for meiosis in male mice.
Han TT, Wang LY, Zhou QX, Wei W, Ma YJ, Chen YH, Li W, Ju ZY, Liu C
Zoological research 2025 Jan 18;46(1):27-40
Zoological research 2025 Jan 18;46(1):27-40
The Role of TRPV1/CGRP Pathway Activated by Prevotella melaninogenica in Pathogenesis of Oral Lichen Planus.
Xu P, Shao R, Zhu P, Fei J, He Y
International journal of molecular sciences 2025 Jan 14;26(2)
International journal of molecular sciences 2025 Jan 14;26(2)
Microglia phagocytosis of PNNs mediates PV-positive interneuron dysfunction and associated gamma oscillations in neuroinflammation-induced cognitive impairment in mice.
Liu K, Gao YZ, Wu XM, Hu XY, Shi CN, He QL, Wu HP, Yao H, Ma DQ, Yang JJ, Ji MH
Neuropharmacology 2025 Jan 1;262:110205
Neuropharmacology 2025 Jan 1;262:110205
AAV mediated carboxyl terminus of Hsp70 interacting protein overexpression mitigates the cognitive and pathological phenotypes of APP/PS1 mice.
Hu Z, Yang J, Zhang S, Li M, Zuo C, Mao C, Zhang Z, Tang M, Shi C, Xu Y
Neural regeneration research 2025 Jan 1;20(1):253-264
Neural regeneration research 2025 Jan 1;20(1):253-264
AFP shields hepatocellular carcinoma from macrophage phagocytosis by regulating HuR-mediated CD47 translocation in cellular membrane.
Pan Y, Yin Q, Wang Z, Wu G, Liu K, Li X, Liu J, Zeng J, Lin B, Li W, Zhu M, Li M
Translational oncology 2025 Feb;52:102240
Translational oncology 2025 Feb;52:102240
Chronic environmental exposure to polystyrene microplastics increases the risk of nonalcoholic fatty liver disease.
Shi Y, Hong R, Fan Z, Huan R, Gao Y, Ma M, Liu T, Pan C
Toxicology 2025 Feb;511:154067
Toxicology 2025 Feb;511:154067
E3 ubiquitin ligase CHIP facilitates cAMP and cGMP signalling cross-talk by polyubiquitinating PDE9A.
Hao X, Hu Z, Li M, Zhang S, Tang M, Hao C, Qi S, Liang Y, Almeida MF, Smith K, Zuo C, Feng Y, Guo M, Ma D, Li S, Wang Z, Sun Y, Deng Z, Mao C, Xia Z, Jiang Y, Gao Y, Xu Y, Schisler JC, Shi C
The EMBO journal 2025 Feb;44(4):1249-1273
The EMBO journal 2025 Feb;44(4):1249-1273
H(2)S Donor SPRC Ameliorates Ischemic Stroke by Upregulating CD24.
Wang C, Li S, Li Q, Xi H, Li J, Zhu Q, Wu P, Zhu YZ, Mao Y
CNS neuroscience & therapeutics 2025 Feb;31(2):e70243
CNS neuroscience & therapeutics 2025 Feb;31(2):e70243
The PROTAC selectively degrading BCL-X(L) inhibits the growth of tumors and significantly synergizes with Paclitaxel.
Qiu F, Tao Y, Chen Y, Shen Z, Huang X, Tan W, Huang T, Cao X
Biochemical pharmacology 2025 Feb;232:116731
Biochemical pharmacology 2025 Feb;232:116731
SMURF1 leads to the β-catenin signaling-mediated progression of esophageal squamous carcinoma by losing PATZ1-induced CCNG2 transcription.
Chen L, Tang J, Chang Y, Hang D, Ji J, Chen G
Biochemical pharmacology 2025 Feb;232:116688
Biochemical pharmacology 2025 Feb;232:116688
VNS facilitates the neurological function recovery after ischemia/reperfusion injury by regulating the A1/A2 polarization of astrocytes through the NMU-NMUR2 pathway.
Jiang X, Yang W, Liu G, Tang H, Zhang R, Zhang L, Li C, Li S
Neurochemistry international 2025 Feb;183:105918
Neurochemistry international 2025 Feb;183:105918
PPARβ/δ Activation Improves Corticosterone-Induced Oxidative Stress Damage in Astrocytes by Targeting UBR5/ATM Signaling.
Ji J, Chen YF, Hong C, Ren XW, Xu H, Cai ZY, Dong YF, Sun XL
Journal of neurochemistry 2025 Feb;169(2):e70013
Journal of neurochemistry 2025 Feb;169(2):e70013
Melittin suppresses ovarian cancer growth by regulating SREBP1-mediated lipid metabolism.
Wu R, Li N, Huang W, Yang Y, Zang R, Song H, Shi J, Zhu S, Liu Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156367
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156367
Clofarabine induces tumor cell apoptosis, GSDME-related pyroptosis, and CD8(+) T-cell antitumor activity via the non-canonical P53/STING pathway.
Wu J, Liu N, Chen J, Tao Q, Lu C, Li Q, Chen X, Peng C
Journal for immunotherapy of cancer 2025 Feb 6;13(2)
Journal for immunotherapy of cancer 2025 Feb 6;13(2)
CircGRB14 Inhibits Proliferation and Promotes Apoptosis of Granulosa Cells in Chicken Follicle Selection Through Sponging miR-12264-3p and miR-6660-3p.
Yang H, Li M, Zhang B, Zhang J, Shi Y, Ma T, Sun Y
International journal of molecular sciences 2025 Feb 28;26(5)
International journal of molecular sciences 2025 Feb 28;26(5)
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
Wang M, Yang S, Li X, Zheng Y, Bai Y, Luo W, Zhu G, Chang J, Zhu B
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
Bridging the gap: investigating the role of phosphorylation at the serine 129 site of α-synuclein in VAPB-PTPIP51 interactions.
Liu W, Lu Y, Liu J, Yu Y, Yang H
Acta neuropathologica communications 2025 Feb 24;13(1):40
Acta neuropathologica communications 2025 Feb 24;13(1):40
α-Cyperone Alleviates LPS-Induced Pyroptosis in Rat Aortic Endothelial Cells via the PI3K/AKT Signaling Pathway.
Liu S, Zhang Y, Liang X, Yin L, He C
Pharmaceuticals (Basel, Switzerland) 2025 Feb 22;18(3)
Pharmaceuticals (Basel, Switzerland) 2025 Feb 22;18(3)
In vitro analysis of the molecular mechanisms of ursolic acid against ovarian cancer.
Zhang R, Zhang Z, Xie L, Yu Z, Gao R, Zhang ZR, Zhang Y, Wei X, Chen Y, Jiao S, Gao Y, Guo JP
BMC complementary medicine and therapies 2025 Feb 21;25(1):65
BMC complementary medicine and therapies 2025 Feb 21;25(1):65
O-GlcNAcylation of DJ-1 suppresses ferroptosis in renal cell carcinoma by affecting the transsulfuration pathway.
Yan Z, Li Y, Wang M, Xu K, Liu Y, Wang L, Luo H, Chen Z, Liu X
International immunopharmacology 2025 Feb 20;148:114098
International immunopharmacology 2025 Feb 20;148:114098
Exploring macrophage and nerve interaction in endometriosis-associated pain: the inductive role of IL-33.
Li J, Wu Z, Li N, Wang J, Huang M, Zhu L, Wan G, Zhang Z
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Feb 19;74(1):42
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Feb 19;74(1):42
Structural Characterization of APSN from Astragalus membranaceus and Its Potential Therapeutic Effect on Immune Dysregulation and Tissue Damage.
Hu L, Sun Q, Liu Z, Huang H, Zhao E, Chen H, Wu Y, Ge Y, Ouyang D, Tang B
Journal of agricultural and food chemistry 2025 Feb 19;73(7):4042-4054
Journal of agricultural and food chemistry 2025 Feb 19;73(7):4042-4054
p16(INK4a) promoted progress of MCT induced pulmonary hypertension via maintaining redox balance and autophagy pathway.
Wang F, Xiao W, Li J, Zhang Z, Zhang X, Sun J, Zhong Y, Wang X, Zhuang R, Gu X
Biochemical and biophysical research communications 2025 Feb 16;749:151385
Biochemical and biophysical research communications 2025 Feb 16;749:151385
Eriodictyol-cisplatin coated nanomedicine synergistically promote osteosarcoma cells ferroptosis and chemosensitivity.
Lin Z, Li Y, Wu Z, Liu Q, Li X, Luo W
Journal of nanobiotechnology 2025 Feb 14;23(1):109
Journal of nanobiotechnology 2025 Feb 14;23(1):109
Inhibition of SCF(KDM2A)/USP22-dependent nuclear β-catenin ubiquitylation mediates cerebral ischemic tolerance.
Zuo Y, Xue J, Wen H, Zhan L, Chen M, Sun W, Xu E
Communications biology 2025 Feb 11;8(1):214
Communications biology 2025 Feb 11;8(1):214
Dihuang Yinzi improves scopolamine-induced learning and memory impairment by regulating plasma exosome-derived BDNF.
Su W, Du Y, Wang W, Li Q, Zhang J, He W
Journal of ethnopharmacology 2025 Feb 11;341:119322
Journal of ethnopharmacology 2025 Feb 11;341:119322
Antidepressant and anxiolytic effects of Wuling Capsule in CSDS mice: Alleviating HPA axis hyperactivity via the Nesfatin-1/NF-κB signaling pathway.
Zheng J, Han J, Wang Y, Xu Y, Yu J, Han B, Tian Z
Journal of ethnopharmacology 2025 Feb 10;338(Pt 3):119111
Journal of ethnopharmacology 2025 Feb 10;338(Pt 3):119111
MDPAO1 peptide from human milk enhances brown adipose tissue thermogenesis and mitigates obesity.
Gao Y, Zhang J, Cao M, Zhang Y, Cao M, Gu W, Wang M
Molecular and cellular endocrinology 2025 Feb 1;597:112443
Molecular and cellular endocrinology 2025 Feb 1;597:112443
PINK1 overexpression suppresses p38 MAPK/NF‑κB signaling to attenuate chondrocyte senescence in osteoarthritis.
Jie L, Zhang Y, Liu J, Fu H, Zhu Z, Huang Z, Shi X, Wang P, Yin S
International journal of molecular medicine 2025 Dec;56(6)
International journal of molecular medicine 2025 Dec;56(6)
Sodium-Glucose Cotransporter 2 Inhibitor Ameliorate Angiotensin II-Induced Hypertension and Vascular Injury by Upregulating FGF21.
Dai M, Jia Z, Wang H, Zheng P, Xue Y, Gong K, Zhao R
Inflammation 2025 Dec;48(6):4031-4045
Inflammation 2025 Dec;48(6):4031-4045
Dietary baking soda (NaHCO(3)) therapy recovered urolithiasis-induced kidney injury in mice by inhibition of oxidative stress, pyroptosis, and inflammation through gut-kidney axis.
Liu S, Gao Y, Luo J, Chen Y, Cao H, Guo Z, Zhou H, Hong Z, Chen B, Xu X, Zhang J, Duan N, Zhan X, Yao X, Xie T, Dong Y, Xu Y
Renal failure 2025 Dec;47(1):2521456
Renal failure 2025 Dec;47(1):2521456
TM4SF1 as a Prognostic Biomarker and Therapeutic Target in Cervical Cancer.
Deng JX, Zhang LY, Ouyang ZQ, Guo T, Shen FJ, Zheng HY
Current medical science 2025 Dec;45(6):1367-1381
Current medical science 2025 Dec;45(6):1367-1381
Atf3 Deficiency Promotes Mesodermal Commitment and Enhances Endothelial Differentiation in Embryonic Stem Cells.
Jiang Z, Su L, Chen C, He R, Jiang L, Shu Y, Dai D, Wu M, Guo A, Liu J, Liu S, Liu Z
Arteriosclerosis, thrombosis, and vascular biology 2025 Dec;45(12):2226-2242
Arteriosclerosis, thrombosis, and vascular biology 2025 Dec;45(12):2226-2242
Integrated multi-omics analysis reveals TMEM147 as an immunosuppressive prognostic biomarker in LUAD.
Ding L, Ding Y
Biochemistry and biophysics reports 2025 Dec;44:102281
Biochemistry and biophysics reports 2025 Dec;44:102281
Anti-tumor analysis of the RIG-I agonist in vitro and in vivo.
Wang Q, Song Z, Cui B, An C, Gao F, Liu M, Li L, Ma X, Wu X, Liang Z
Biochemistry and biophysics reports 2025 Dec;44:102249
Biochemistry and biophysics reports 2025 Dec;44:102249
Chlormequat chloride inhibited thyroid hormone in the pregnant rats by regulating sodium/iodide symporter.
Celigeer, Tian W, Wu Z, Huang Y, Huang X, Xiagedeer B
Toxicology letters 2025 Dec;414:111772
Toxicology letters 2025 Dec;414:111772
STC2 Serves as a Critical Hypoxic Effector in Keloid Pathogenesis by Orchestrating Fibroblasts Activation and ECM Remodelling.
Qian L, Deng S, Tian T, He Y, Li Y, Wang X, Tian T, Jiang M, Pan Y, Li D
Experimental dermatology 2025 Dec;34(12):e70193
Experimental dermatology 2025 Dec;34(12):e70193
A novel covalent inhibitor alleviates type 2 diabetes mellitus by restraining GSK-3β.
Zhang S, Zhao F, Pan C, Wang Y, Yang Z, Yang J, Meng Y, Lv S, Huang J, Dong L, Li L, Dong Y
Biochemical pharmacology 2025 Dec;242(Pt 2):117205
Biochemical pharmacology 2025 Dec;242(Pt 2):117205
Low-Intensity pulsed ultrasound inhibits the ROS/NF-κB signaling pathway and improves inflammation in ovarian granulosa cells of PCOS rats.
Hu R, Huang B, Zhao X, Cui X, Luo P, Mao X, Long C, He Y, Shen Z, Chen J, Peng H, Dong W, Lei X, Zhang S, Zhang J
Biochemical pharmacology 2025 Dec;242(Pt 1):117281
Biochemical pharmacology 2025 Dec;242(Pt 1):117281
Gut microbes-spinal connection is required for itch sensation.
Jin T, Li SY, Zheng HL, Liu XD, Huang Y, Ma G, Zhao YX, Zhao XT, Yang L, Wang QH, Wang HJ, Gu C, Pan Z, Lin F
Gut microbes 2025 Dec;17(1):2495859
Gut microbes 2025 Dec;17(1):2495859
Ferroptosis is important for Toxoplasma gondii replication and virulence in vitro and in vivo.
Li LY, Zhou CX, Han B, Elsheikha HM, Qiu HJ, An XD, Zeng T, Liu DA, Yang Q, Zhu XQ, Zhou HY
Virulence 2025 Dec;16(1):2530164
Virulence 2025 Dec;16(1):2530164
Elevated SNHG15 empowers keratinocytes hyperproliferation through activation of STAT3/Cyclin D1 axis in psoriasis.
Tang L, Li G, Chang J, Xian H, Liu Y, Lin L, Dai Z, Liu Z, Qiu X, Zhang B, Su Z, Feng B, Zhu Y, Wang M, Chen Y, Liu H, Wu D, Li C, Zhao J, Li M, Zhu Y, Xie X, Deng H, Ye S, Fan S, Bi H, Lu C, Zheng G
Acta pharmaceutica Sinica. B 2025 Dec;15(12):6430-6443
Acta pharmaceutica Sinica. B 2025 Dec;15(12):6430-6443
CAPG enhances adipogenesis and inflammatory cytokine expression in adipocytes.
Zhang L, Sang B, Li S, Li Y, Guo D, Ma QN, Liu X, Li X, Chen B, Liu D
Adipocyte 2025 Dec;14(1):2549456
Adipocyte 2025 Dec;14(1):2549456
Andrographolide drives dual apoptosis and ferroptosis via caspase-3 and FACL4 in T-ALL cell lines.
Doi H, Akiyama H, Matsui T, Shiogama K, Hirayama M, Nakagawa R, Fujii S, Matsuura H, Miura Y
International journal of hematology 2025 Dec;122(6):843-855
International journal of hematology 2025 Dec;122(6):843-855
Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain-Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model.
Zhang Z, Zhang Y, Si J, Mao H, He F, Ning J, Ma G, Chen X, Xiao H, Zhu Y, Zhang H, Lu Y, Liu Q, Nian M, Sun S, Yu S, Wu S, Fan Z, Jin Z, Huang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e09509
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e09509
Transcriptome analysis reveals reduced lipid accumulation and mitochondrial metabolic remodeling in ADCY3-overexpressing adipocytes.
Liu L, Cui H, Xiang Z, Dong N, Niu D
Functional & integrative genomics 2025 Dec 6;25(1):266
Functional & integrative genomics 2025 Dec 6;25(1):266
Multi-omics analysis reveals that ALYREF-mediated m(5)C modification promotes platinum resistance in ovarian cancer via the NSUN2/ALYREF/LGR4 axis.
Yang S, He P, Wang W, Xu X, Xi X, Li Y
Cell death & disease 2025 Dec 5;17(1):77
Cell death & disease 2025 Dec 5;17(1):77
GSDMD deficiency attenuates BPD by suppressing macrophage pyroptosis and promoting M2 polarization.
Yang X, Wang X, Yang Y, Ma Y, Liu X, Mo D, Guo C, Han W
Cell death discovery 2025 Dec 4;12(1):33
Cell death discovery 2025 Dec 4;12(1):33
Activated oligoadenylate synthetase-ribonuclease L pathway promotes endothelial pyroptosis and impairs diabetic wound healing via thioredoxin-interacting protein m(6)A methylation.
Zhou P, Huang Y, Wang Z, Chen D, Long B, Qin P, Li Y, Yang C, Li Q
Molecular biomedicine 2025 Dec 29;6(1):150
Molecular biomedicine 2025 Dec 29;6(1):150
EXOSC3 knockdown induces G1/S phase arrest to suppress hepatocellular carcinoma cell proliferation.
Chen YM, Huo YX, Wei WS, Liu YX, Wang SH, Jiang L, Rong-He, Zhang HL, Jiang LH
Scientific reports 2025 Dec 29;15(1):44684
Scientific reports 2025 Dec 29;15(1):44684
Cathepsin C-driven enhancement of neutrophil extracellular trap formation contributes to acute lung injury.
Wu X, Liu H, Qin Q, Yuan L, Yao Y, Du X, Qin Q, Wang L, Zhao Q, Qin L, Xiang Y, Yang M, Qin X, Liu C
iScience 2025 Dec 19;28(12):113928
iScience 2025 Dec 19;28(12):113928
STAT2 Promotes Tumor Growth in Colorectal Cancer Independent of Type I IFN Receptor Signaling.
Canar J, Bono M, Alvarado A, Slifker M, Sitia G, Gamero AM
Current oncology (Toronto, Ont.) 2025 Dec 16;32(12)
Current oncology (Toronto, Ont.) 2025 Dec 16;32(12)
Discovery of a heterocyclic aromatic amide based P-gp inhibitor as coadjutant regulating autophagy against drug resistance in breast cancer.
Xue WH, Zhang X, Guo S, Yu H, Man RY, Lu PF, Ge GH, Liu HY, Meng FH, Zhang TJ
European journal of medicinal chemistry 2025 Dec 15;300:118151
European journal of medicinal chemistry 2025 Dec 15;300:118151
Exercise-induced histone lactylation in monocyte-derived macrophages restores cardiac immune homeostasis and function in sepsis-induced cardiomyopathy.
Sun S, Lai C, Huang C, Ren X, Zhang T, Zou J, Tong Y, Zhou Q, Lu J, Shen Z, Chen W, Wang R, Rabrenovic N, Wang X, Ma B, Qian J, Fu G, Shang M
Nature communications 2025 Dec 15;17(1):756
Nature communications 2025 Dec 15;17(1):756
β-caryolane derivatives as novel anti-colorectal cancer agents: synthesis and in vitro biological evaluation.
Xu X, Wang Z, Huang A, Qiao Z, Ge Y, Wen H, Cheng J, Zhao Y, Liang X
RSC advances 2025 Dec 12;15(58):49739-49750
RSC advances 2025 Dec 12;15(58):49739-49750
RalGAP complexes control secretion and primary cilia in pancreatic disease.
Apken LH, Barz H, Beel S, Michalke E, Rasche R, Verma A, Ricker A, Nüsse H, Klingauf J, Kerl K, Wardelmann E, Kümmel D, Steinestel K, Pethő Z, Meisterernst M, Oeckinghaus A
Life science alliance 2025 Aug;8(8)
Life science alliance 2025 Aug;8(8)
Cardiomyocyte-localized CCDC25 senses NET DNA to promote doxorubicin cardiotoxicity by activating autophagic flux.
Nie M, Lei D, Liu Z, Zeng K, Liang X, Huang P, Wang Y, Sun P, Yang H, Liu P, Nie R, Huang S, Song E, Jiang W, Li Z, Yang Y, Xia Y, Yang L
Nature cancer 2025 Aug;6(8):1400-1418
Nature cancer 2025 Aug;6(8):1400-1418
An RNA G-quadruplex within the sclerostin 3' untranslated region enhances sclerostin expression by blocking miR-4648 binding.
Duan X, Luo J, Hong Z, Song Z, Chen Z, Song D, Wang S, Chen XC, Lu YJ, Jin F
International journal of biological macromolecules 2025 Aug;319(Pt 1):145405
International journal of biological macromolecules 2025 Aug;319(Pt 1):145405
Trimethylamine N-Oxide Mitigates Perioperative Neurocognitive Disorders via ANXA1 Nuclear Translocation and M2 Microglial Polarization in the Hippocampus.
Que M, Luo L, Wang X, Li S, Xia Q, Li X, Luo A, Zhan G
CNS neuroscience & therapeutics 2025 Aug;31(8):e70558
CNS neuroscience & therapeutics 2025 Aug;31(8):e70558
Leber's hereditary optic neuropathy-associated ND1 3733G>C mutation ameliorates the mitochondrial quality control and cellular homeostasis.
Yasheng M, Ji Y, He Y, Yi Q, Zhang H, Shan W, Wang K, Zhang J, Li Y, Meng F, Zhang M, Mo JQ, Wei S, Guan MX
The Journal of biological chemistry 2025 Aug;301(8):110464
The Journal of biological chemistry 2025 Aug;301(8):110464
Purinergic P2X7 receptor involves in anti-retinal photodamage effects of berberine.
Ye SS, Wang JN, Zhao YF, Dai LS, Zhang JZ, Zuo YQ, Song JT
Purinergic signalling 2025 Aug;21(4):675-685
Purinergic signalling 2025 Aug;21(4):675-685
Electroacupuncture regulates the P2X(7)R-NLRP3 inflammatory cascade to relieve decreased sensation on ocular surface of type 2 diabetic rats with dry eye.
Wan MM, Fu ZY, Jin T, Wang ZY, Sun XY, Gao WP
Purinergic signalling 2025 Aug;21(4):651-666
Purinergic signalling 2025 Aug;21(4):651-666
Cardiopulmonary Bypass-Induced IL-17A Aggravates Caspase-12-Dependent Neuronal Apoptosis Through the Act1-IRE1-JNK1 Pathway.
Zhao R, Ma Y, Li S, Li J
Biomolecules 2025 Aug 6;15(8)
Biomolecules 2025 Aug 6;15(8)
RIPK1 senses S-adenosylmethionine scarcity to drive cell death and inflammation.
Chen Z, Gu X, Chen H, Zhang H, Liu J, Yang X, Cai Y, Zhang M, Yan L, Yang Y, Shan B, Zhu ZJ, Zhang Y, Gu J, Xu D
Cell metabolism 2025 Aug 5;37(8):1732-1749.e9
Cell metabolism 2025 Aug 5;37(8):1732-1749.e9
Dimethyl fumarate improves non-alcoholic fatty liver disease by regulating SIRT1 signal to inhibit MAMs over-enrichment.
Zhang R, Zhang Q, Cui Z, Huang B, Wang Y, Ma H
European journal of pharmacology 2025 Aug 5;1000:177693
European journal of pharmacology 2025 Aug 5;1000:177693
PGRP-S promotes hepatocellular carcinoma progression via MAPK/ERK pathway by interaction with TTC1.
Zhu H, Feng S, Lv S, Zhao D, Chang X, Fan S, Wang X, Qian X
Scientific reports 2025 Aug 4;15(1):28367
Scientific reports 2025 Aug 4;15(1):28367
Targeting phagocytosis for amyloid-β clearance: implications of morphology remodeling and microglia activation probed by bifunctional chimaeras.
Wang Y, Wang Z, Liu Z, Li J, Yang S, Zhao Y, Huang Y, Liao C, Zhang Y, Zhao J, Zhou W, Zhou B, Yue X, Zhou Q, Bu X
Nature communications 2025 Aug 30;16(1):8128
Nature communications 2025 Aug 30;16(1):8128
Construction of lactylation (LA) risk signature in prostate cancer based on 4D fast DIA L-lactated quantitative genomics.
Zou F, Jin Y, Zhang Z, Zhang Y, Wang M, Zhu F, Qiu J, Ye H, Fu Y, Ping H
Journal of translational medicine 2025 Aug 28;23(1):967
Journal of translational medicine 2025 Aug 28;23(1):967
Anti-Obesity Effects of Pea Peptides Modified by Steam Explosion on Obese Mice: Regulation of Gut Microbiota and Glucose Metabolism.
Tu J, Liu C, Zhang J, Li T, Zhu J, Wang Q, Wu R, Wang T
Foods (Basel, Switzerland) 2025 Aug 28;14(17)
Foods (Basel, Switzerland) 2025 Aug 28;14(17)
Anterior cingulate cortex mediates the comorbidity between colorectal cancer and depression-like behaviors.
Huang M, He S, Wang Y, Zeng Y, Chen Q, Chen Y, Wang X, Li Y, Chen L, Zheng S, Wang Y, Mo S, Han A, Xia P
Communications biology 2025 Aug 27;8(1):1284
Communications biology 2025 Aug 27;8(1):1284
Cyclooxygenase-1 deletion in 5 × FAD mice protects against microglia-induced neuroinflammation and mitigates cognitive impairment.
Wang J, Ni H, Wang Y, Wei L, Ding H, Guo Z, Pan H, Yu Y, Luo J, Pan W, Wang D, Ke ZJ
Translational neurodegeneration 2025 Aug 22;14(1):43
Translational neurodegeneration 2025 Aug 22;14(1):43
Oncogenic GOPC-ROS1 fusion promotes the formation of lymphatic malformations by impairing tight junction and its crizotinib resistance through repressing ferroptosis.
Tian R, Weng Z, Liang H, Zhang C, He Q, Li J, Zhang R, Yin X, Deng D, Hong L, Gu S, Zhan Z
Biochemical pharmacology 2025 Aug 15;242(Pt 1):117243
Biochemical pharmacology 2025 Aug 15;242(Pt 1):117243
High expression of LIMD2 predicts a poor prognosis and promotes migration of colon cancer cells.
Wang J, Cai F, Liu G, Zhang J, Li D, Cai Y, Wang Y, Xu W, Wang X, Li X
Discover oncology 2025 Aug 14;16(1):1550
Discover oncology 2025 Aug 14;16(1):1550
GDF15 attenuates myocardial hypoxic injury by inhibiting mitochondrial damage through BNIP3 pathway.
Huang J, Pan B, He Z, Liu Y, Wang C, Tong J, Shao J, Tang X, Hou P, Ding X, Wang H, Zhu H
Molecular biology reports 2025 Aug 13;52(1):825
Molecular biology reports 2025 Aug 13;52(1):825
Chondroitin sulfate protects against synaptic impairment caused by fluorosis through the Erk1/2-MMP-9 signaling pathway.
Ai F, Wang S, Ye L, Wan W, Zhou X, Liu M, Mo K, Lu Y, Wei N, Guan Z, Liu Y
Scientific reports 2025 Aug 13;15(1):29760
Scientific reports 2025 Aug 13;15(1):29760
MOSPD1 facilitates fatty acid metabolism and gastric cancer progression by promoting the MAPK pathway.
Wang C, Qiu Y, Zheng X, Chen S, He C
Tissue & cell 2025 Apr;93:102752
Tissue & cell 2025 Apr;93:102752
TFAP4 Regulation of MCM5 Activates the PI3K/AKT Pathway to Promote Invasion and Metastasis of Gastric Cancer.
Yuan YW, Yue ZQ, Zhou Q, Sheng J, Zou YH, Fan LJ, Xu H, Xin L
Digestive diseases and sciences 2025 Apr;70(4):1411-1427
Digestive diseases and sciences 2025 Apr;70(4):1411-1427
The property of larval cells of the scleractinian coral, Acropora tenuis, deduced from in vitro cultured cells.
Kawamura K, Sekida S, Nishitsuji K, Satoh N
Development, growth & differentiation 2025 Apr;67(3):119-135
Development, growth & differentiation 2025 Apr;67(3):119-135
Targeted sonodynamic therapy induces tumor cell quasi-immunogenic ferroptosis and macrophage immunostimulatory autophagy in glioblastoma.
Wang MF, Guo J, Yuan SJ, Li K, Zhang Q, Lei HM, Wu JL, Zhao L, Xu YH, Chen X
Biomaterials 2025 Apr;315:122913
Biomaterials 2025 Apr;315:122913
Mycoplasma ovipnuemoniae impairs the immune response of sheep and suppresses neutrophil function by inhibiting S100A9.
Yan C, Dong T, Shan Y, Zhao B, Yang H, Cai Y, Li S, Liu Q, Chu Y, Hao H, Cheng Z, Liu M, Zhang Y
Veterinary microbiology 2025 Apr;303:110446
Veterinary microbiology 2025 Apr;303:110446
Integrative Multi-Omics Approaches Reveal Selectivity Profiles and Molecular Mechanisms of FIIN-2, a Covalent FGFR Inhibitor.
Fu Y, Zhu D, Chen X, Qu L, Guo M, Zhang S, Xu G, Chen Z, Li M, Chen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2412578
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(14):e2412578
The INO80E at 16p11.2 locus increases risk of schizophrenia in humans and induces schizophrenia-like phenotypes in mice.
Hu B, Yin MY, Zhang CY, Shi Z, Wang L, Lei X, Li M, Li SW, Tuo QH
EBioMedicine 2025 Apr;114:105645
EBioMedicine 2025 Apr;114:105645
Tanshinone IIA Ameliorates Myocardial Ischemia-Reperfusion Injury via Activating HDAC1-Repressed Nrf2-xCT/Gpx4/HO-1 Axis.
Yan K, Yu S, Gao X, Li L, Ding L
Chemical biology & drug design 2025 Apr;105(4):e70095
Chemical biology & drug design 2025 Apr;105(4):e70095
The African swine fever virus gene MGF_360-4L inhibits interferon signaling by recruiting mitochondrial selective autophagy receptor SQSTM1 degrading MDA5 antagonizing innate immune responses.
Sun H, Yang J, Zhang Z, Wu M, Tian Z, Liu Y, Zhang X, Zhong J, Yang S, Chen Y, Luo J, Guan G, Yin H, Niu Q
mBio 2025 Apr 9;16(4):e0267724
mBio 2025 Apr 9;16(4):e0267724
Lacc1-engineered extracellular vesicles reprogram mitochondrial metabolism to alleviate inflammation and cartilage degeneration in TMJ osteoarthritis.
Hu X, Xie J, Su J
Journal of nanobiotechnology 2025 Apr 5;23(1):276
Journal of nanobiotechnology 2025 Apr 5;23(1):276
Inhaled exogenous thymosin beta 4 suppresses bleomycin-induced pulmonary fibrosis in mice via TGF-β1 signalling pathway.
Yu R, Li S, Chen L, Hu E, Chai D, Liu Z, Zhang Q, Mao Y, Zhai Y, Li K, Liu Y, Li X, Zhou H, Yang C, Xu J
The Journal of pharmacy and pharmacology 2025 Apr 3;77(4):582-592
The Journal of pharmacy and pharmacology 2025 Apr 3;77(4):582-592
FAM20B-Catalyzed Glycosylation Regulates the Chondrogenic and Osteogenic Differentiation of the Embryonic Condyle by Controlling IHH Diffusion and Release.
Chen X, Liu H, Huang Y, Li L, Jiang X, Liu B, Li N, Zhu L, Liu C, Xiao J
International journal of molecular sciences 2025 Apr 24;26(9)
International journal of molecular sciences 2025 Apr 24;26(9)
LAMP2A-mediated neuronal hyperexcitability by enhancing NKAβ1 degradation underlies depression-induced allodynia.
Zhang Y, Wu H, Zhang Q, Cong P, Li Z, Wu Q, Huang X, Li X, Feng B, Liu Q, Xiong L
Cell reports 2025 Apr 22;44(4):115489
Cell reports 2025 Apr 22;44(4):115489
GAMT facilitates tumor progression via inhibiting p53 in clear cell renal cell carcinoma.
Zheng B, Liu K, Feng J, Ouyang Q, Jia T, Wang Y, Tian S, Chen X, Cai T, Wen L, Zhang X, Li X, Ma X
Biology direct 2025 Apr 2;20(1):43
Biology direct 2025 Apr 2;20(1):43
The interaction between IL-33 and TRIM28 in the regulation of macrophage polarization in an ST2-independent manner.
Zhao Y, Xu H, Liu Q, Yuan Y, Li R, Li D, Zhang Y, Ran J, Yan X, Su J
International immunopharmacology 2025 Apr 16;152:114318
International immunopharmacology 2025 Apr 16;152:114318
Troxerutin suppresses the stemness of osteosarcoma via the CD155/SRC/β-catenin signaling axis.
Chen J, Li H, Jin Q, Li X, Zhang Y, Shen J, Huang G, Yin J, Zou C, Li X, He X, Xie X, Lin T
Cellular & molecular biology letters 2025 Apr 11;30(1):45
Cellular & molecular biology letters 2025 Apr 11;30(1):45
Preclinical evaluation of AGT mRNA replacement therapy for primary hyperoxaluria type I disease.
Yang T, Ge J, Huang L, Zhu X, Zhang D, Tang S, Zhao J, Ma Y, Long M, Bo X, Li J, Zhang Y, Yuan Q, Sharma AD, Ott M, Geng H, Zhao Y, Zhang L, Shen H, Li H, Li D, Wan P, Xia Q
Science advances 2025 Apr 11;11(15):eadt9694
Science advances 2025 Apr 11;11(15):eadt9694
Development of an iridium complex fluorescent probe for FGF21 protein labeling and tracking.
Zhang L, Du S, Ji W, Li J, Ma R, Yan D, Niu Y, Zhao S, Ru J, Gao Y
Scientific reports 2025 Apr 10;15(1):12365
Scientific reports 2025 Apr 10;15(1):12365
Aquaporin 9 downregulation in KRAS(G12V) colorectal cancer and associated with increased proliferation and decreased apoptosis in cancer cells.
Liu Y, Dou J, Tan Q, Chen S, Li Y, Wang R, Sun N, Qi X
Scientific reports 2025 Apr 10;15(1):12298
Scientific reports 2025 Apr 10;15(1):12298
In vitro susceptibility of differentiated SH-SY5Y human neuroblastoma cells to herpes simplex virus type 1 and Japanese encephalitis virus infection.
Ferdous J, Makino H, Masatani T, Fujimoto Y, Naitou K, Shiraishi M
The Journal of veterinary medical science 2025 Apr 1;87(4):426-430
The Journal of veterinary medical science 2025 Apr 1;87(4):426-430
KGF-2 Alleviates Dry Eye Disease by Regulating the HMGB1/TLR4 Pathway.
Wang Y, Xu Z, Wei L, Lu Y, Shi Y, Wen S, Lv X, Huang K, Lu F, Qu J, Hu L
Investigative ophthalmology & visual science 2025 Apr 1;66(4):28
Investigative ophthalmology & visual science 2025 Apr 1;66(4):28
Idebenone improves mitochondrial respiratory activity and attenuates oxidative damage via the SIRT3-SOD2 pathway in a prion disease cell model.
Sun Z, Wen P, Yang D, Li J, Li Z, Zhao M, Wang D, Gou F, Wang J, Fan Q, Dai Y, Ji Y, Li X, Tu Y, Ma T, Wang X, Zhao D, Yang L
Life sciences 2025 Apr 1;366-367:123481
Life sciences 2025 Apr 1;366-367:123481
Genome-Wide Mendelian Randomization Identifies Ferroptosis-Related Drug Targets for Alzheimer's Disease.
Wang Y, Song X, Wang R, Xu X, Du Y, Chen G, Mei J
Journal of Alzheimer's disease reports 2024;8(1):1185-1197
Journal of Alzheimer's disease reports 2024;8(1):1185-1197
Electroacupuncture Improves Cardiac Function via Inhibiting Sympathetic Remodeling Mediated by Promoting Macrophage M2 Polarization in Myocardial Infarction Mice.
Peng R, Shi J, Jiang M, Qian D, Yan Y, Bai H, Yu M, Cao X, Fu S, Lu S
Mediators of inflammation 2024;2024:8237681
Mediators of inflammation 2024;2024:8237681
Comparative Analysis of the Therapeutic Effects of MSCs From Umbilical Cord, Bone Marrow, and Adipose Tissue and Investigating the Impact of Oxidized RNA on Radiation-Induced Lung Injury.
Zhai R, Tai F, Ding K, Tan X, Li H, Cao Z, Ge C, Zheng X, Fu H
Stem cells international 2024;2024:7419270
Stem cells international 2024;2024:7419270
USP10 promotes pancreatic ductal adenocarcinoma progression by attenuating FOXC1 protein degradation to activate the WNT signaling pathway.
Wang J, Gan L, Liu F, Yang Q, Deng Q, Jiang D, Zhang C, Zhang L, Wang X
International journal of biological sciences 2024;20(13):5343-5362
International journal of biological sciences 2024;20(13):5343-5362
Identification and development of Tetra-ARMS PCR-based screening test for a genetic variant of OLA1 (Tyr254Cys) in the human failing heart.
Dubey PK, Dubey S, Singh S, Bhat PD, Pogwizd S, Krishnamurthy P
PloS one 2024;19(6):e0293105
PloS one 2024;19(6):e0293105
Apelin-13-Loaded Macrophage Membrane-Encapsulated Nanoparticles for Targeted Ischemic Stroke Therapy via Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis.
Ma CS, Ma YP, Han B, Duan WL, Meng SC, Bai M, Dong H, Zhang LY, Duan MY, Liu J, Deng AJ, He MT
International journal of nanomedicine 2024;19:9175-9193
International journal of nanomedicine 2024;19:9175-9193
SIRT2 Promotes NLRP3-Mediated Microglia Pyroptosis and Neuroinflammation via FOXO3a Pathway After Subarachnoid Hemorrhage.
Sun JQ, Sheng B, Gao S, Liu XZ, Cui Y, Peng Z, Chen XX, Ding PF, Zhuang Z, Wu LY, Hang CH, Li W
Journal of inflammation research 2024;17:11679-11698
Journal of inflammation research 2024;17:11679-11698
Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activating the Nrf2/HO-1 pathway.
Luan J, Yu M, Gu Q, Zhou X, Shao Y, Chen T, Zhang J, Zhu Z, Song N, Yang J
Frontiers in immunology 2024;15:1532021
Frontiers in immunology 2024;15:1532021
Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.
Zhu Y, Wang Y, Zuo X, Liu S, Cao L, Wang J, Yang Q, Huang Q, Huang Q, Tian M, Ping Y, Wu Q
Frontiers in immunology 2024;15:1525469
Frontiers in immunology 2024;15:1525469
ATP5J regulates microglial activation via mitochondrial dysfunction, exacerbating neuroinflammation in intracerebral hemorrhage.
Ren N, Zhang H, Li T, Ji H, Zhang Z, Wu H
Frontiers in immunology 2024;15:1509370
Frontiers in immunology 2024;15:1509370
Identification and validation of efferocytosis-related biomarkers for the diagnosis of metabolic dysfunction-associated steatohepatitis based on bioinformatics analysis and machine learning.
Cao C, Liu W, Guo X, Weng S, Chen Y, Luo Y, Wang S, Zhu B, Liu Y, Peng D
Frontiers in immunology 2024;15:1460431
Frontiers in immunology 2024;15:1460431
(+)-catechin protects PC12 cells against CORT-induced oxidative stress and pyroptosis through the pathways of PI3K/AKT and Nrf2/HO-1/NF-κB.
Chencen L, Shuo Z, Zhiyu C, Xiaoyu F, Min Z, Pengjiao W, Xiuli G
Frontiers in pharmacology 2024;15:1450211
Frontiers in pharmacology 2024;15:1450211
APP-CD74 axis mediates endothelial cell-macrophage communication to promote kidney injury and fibrosis.
Liu B, Li F, Wang Y, Gao X, Li Y, Wang Y, Zhou H
Frontiers in pharmacology 2024;15:1437113
Frontiers in pharmacology 2024;15:1437113
Synergistic antitumor activity of baicalein combined with almonertinib in almonertinib-resistant non-small cell lung cancer cells through the reactive oxygen species-mediated PI3K/Akt pathway.
Chen T, Zhang P, Cong XF, Wang YY, Li S, Wang H, Zhao SR, Sun XJ
Frontiers in pharmacology 2024;15:1405521
Frontiers in pharmacology 2024;15:1405521
Metrnl inhibits choroidal neovascularization by attenuating the choroidal inflammation via inactivating the UCHL-1/NF-κB signaling pathway.
Zhang L, Li Y, Wu Z, Shen Q, Zeng C, Liu H, Zhang X, Yang J, Liu Q, Tang D, Ou K, Fang Y
Frontiers in immunology 2024;15:1379586
Frontiers in immunology 2024;15:1379586
Xiasangju alleviate metabolic syndrome by enhancing noradrenaline biosynthesis and activating brown adipose tissue.
He C, An Y, Shi L, Huang Y, Zhang H, Fu W, Wang M, Shan Z, Du Y, Xie J, Huang Z, Sun W, Zhao Y, Zhao B
Frontiers in pharmacology 2024;15:1371929
Frontiers in pharmacology 2024;15:1371929
Edaravone dexborneol attenuates oxidative stress in experimental subarachnoid hemorrhage via Keap1/Nrf2 signaling pathway.
Zhu K, Bi S, Zhu Z, Zhang W, Yang X, Li J, Liang G, Yu C, Pan P
Frontiers in pharmacology 2024;15:1342226
Frontiers in pharmacology 2024;15:1342226
TRIM28 facilitates type I interferon activation by targeting TBK1.
Hua F, Nass T Jr, Parvatiyar K
Frontiers in immunology 2024;15:1279920
Frontiers in immunology 2024;15:1279920
A novel brown adipocytes-related gene signature predicts and validates prognosis and immune infiltration of clear cell renal cell carcinoma.
Liu Y, Ouyang Q, Li Q
American journal of cancer research 2024;14(9):4286-4305
American journal of cancer research 2024;14(9):4286-4305
Abnormal mitochondrial iron metabolism damages alveolar type II epithelial cells involved in bleomycin-induced pulmonary fibrosis.
Shao M, Cheng H, Li X, Qiu Y, Zhang Y, Chang Y, Fu J, Shen M, Xu X, Feng D, Han Y, Yue S, Zhou Y, Luo Z
Theranostics 2024;14(7):2687-2705
Theranostics 2024;14(7):2687-2705
Towards modelling tick-virus interactions using the weakly pathogenic Sindbis virus: Evidence that ticks are competent vectors.
Wang Y, Xu Z, Zhang H, Zhou Y, Cao J, Zhang Y, Wang Z, Zhou J
Frontiers in cellular and infection microbiology 2024;14:1334351
Frontiers in cellular and infection microbiology 2024;14:1334351
Matrix metalloproteinase-8 regulates dendritic cell tolerance in late polymicrobial sepsis via the nuclear factor kappa-B p65/β-catenin pathway.
Lu ZQ, Zhang C, Zhao LJ, Dong W, Lv L, Lu Y, Chen XY, Zhang J, Liu XY, Xiao Z, Chen LW, Yao YM, Zhao GJ
Burns & trauma 2024;12:tkad025
Burns & trauma 2024;12:tkad025
PLAUR facilitates the progression of clear cell renal cell carcinoma by activating the PI3K/AKT/mTOR signaling pathway.
Qin T, Huang M, Wei W, Zhou W, Tang Q, Huang Q, Tang N, Gai S
PeerJ 2024;12:e17555
PeerJ 2024;12:e17555
PLEK2: a potential biomarker for metastasis and prognostic evaluation in uveal melanoma.
Liu Y, Wang H, Zhang Q, Gao X, Ji Y, Zhu Y, Zhang J, Luo W
Frontiers in medicine 2024;11:1507576
Frontiers in medicine 2024;11:1507576
N6-methyladenosine triggers renal fibrosis via enhancing translation and stability of ZEB2 mRNA.
Cai Y, Zhou J, Xu A, Huang J, Zhang H, Xie G, Zhong K, Wu Y, Ye P, Wang H, Niu H
The Journal of biological chemistry 2024 Sep;300(9):107598
The Journal of biological chemistry 2024 Sep;300(9):107598
A novel senolytic drug for pulmonary fibrosis: BTSA1 targets apoptosis of senescent myofibroblasts by activating BAX.
Shen M, Fu J, Zhang Y, Chang Y, Li X, Cheng H, Qiu Y, Shao M, Han Y, Zhou Y, Luo Z
Aging cell 2024 Sep;23(9):e14229
Aging cell 2024 Sep;23(9):e14229
Systematic identification of post-transcriptional regulatory modules.
Khoroshkin M, Buyan A, Dodel M, Navickas A, Yu J, Trejo F, Doty A, Baratam R, Zhou S, Lee SB, Joshi T, Garcia K, Choi B, Miglani S, Subramanyam V, Modi H, Carpenter C, Markett D, Corces MR, Mardakheh FK, Kulakovskiy IV, Goodarzi H
Nature communications 2024 Sep 9;15(1):7872
Nature communications 2024 Sep 9;15(1):7872
SIRT1 Regulates Mitochondrial Damage in N2a Cells Treated with the Prion Protein Fragment 106-126 via PGC-1α-TFAM-Mediated Mitochondrial Biogenesis.
Zhao M, Li J, Li Z, Yang D, Wang D, Sun Z, Wen P, Gou F, Dai Y, Ji Y, Li W, Zhao D, Yang L
International journal of molecular sciences 2024 Sep 7;25(17)
International journal of molecular sciences 2024 Sep 7;25(17)
Key subdomains of mesencephalic astrocyte-derived neurotrophic factor attenuate myocardial ischemia/reperfusion injury by JAK1/STAT1/NF-κB signaling pathway.
Dong H, Jia W, Wang C, Teng D, Xu B, Ding X, Yang J, Zhong L, Gong L
Molecular medicine (Cambridge, Mass.) 2024 Sep 6;30(1):139
Molecular medicine (Cambridge, Mass.) 2024 Sep 6;30(1):139
GRP78/IRE1 and cGAS/STING pathway crosstalk through CHOP facilitates iodoacetic acid-mediated testosterone decline.
Mou L, Sun D, Qu J, Tan X, Wang S, Zeng Q, Liu C
Journal of hazardous materials 2024 Sep 5;476:135101
Journal of hazardous materials 2024 Sep 5;476:135101
Developing diagnostic biomarkers for Alzheimer's disease based on histone lactylation-related gene.
Guo S, Zhu W, Bian Y, Li Z, Zheng H, Li W, Yang Y, Ji X, Zhang B
Heliyon 2024 Sep 30;10(18):e37807
Heliyon 2024 Sep 30;10(18):e37807
Duck hepatitis A virus 1-encoded 2B protein disturbs ion and organelle homeostasis to promote NF-κB/NLRP3-mediated inflammatory response.
Mao S, Liu X, Wu D, Zhang Z, Sun D, Ou X, Huang J, Wu Y, Yang Q, Tian B, Chen S, Liu M, Zhu D, Zhang S, Zhao X, He Y, Wu Z, Jia R, Wang M, Cheng A
International journal of biological macromolecules 2024 Sep 23;280(Pt 3):135876
International journal of biological macromolecules 2024 Sep 23;280(Pt 3):135876
The Delayed Turnover of Proteasome Processing of Myocilin upon Dexamethasone Stimulation Introduces the Profiling of Trabecular Meshwork Cells' Ubiquitylome.
Tundo GR, Cavaterra D, Pandino I, Zingale GA, Giammaria S, Boccaccini A, Michelessi M, Roberti G, Tanga L, Carnevale C, Figus M, Grasso G, Coletta M, Bocedi A, Oddone F, Sbardella D
International journal of molecular sciences 2024 Sep 17;25(18)
International journal of molecular sciences 2024 Sep 17;25(18)
Electroacupuncture enhances cerebral blood perfusion by inhibiting HIF-1α in rat subarachnoid hemorrhage.
Wang Y, Chen Y, Li Z, Tang L, Wen D, Wu Y, Guo Z
Brain research 2024 Sep 15;1839:149010
Brain research 2024 Sep 15;1839:149010
Hsa_circ_0000825 promotes the progression of laryngeal squamous cell carcinoma by sponging miR-766 and interacting with ELAVL1.
Yu M, Cao H, Yang J, Liu T, Wang B
Heliyon 2024 Sep 15;10(17):e37264
Heliyon 2024 Sep 15;10(17):e37264
Upregulated SKP2 Empowers Epidermal Proliferation Through Downregulation of P27 Kip1.
Tang L, Zhang B, Li G, Qiu X, Dai Z, Liu H, Zhu Y, Feng B, Su Z, Han W, Huang H, Li Q, Zhang Z, Wang M, Liu H, Chen Y, Zhang Y, Wu D, Zheng X, Liu T, Zhao J, Li C, Zheng G
Annals of dermatology 2024 Oct;36(5):282-291
Annals of dermatology 2024 Oct;36(5):282-291
Prebiotic stachyose inhibits PRDX5 activity and castration-resistant prostate cancer development.
Wang R, Pan Y, Zhang L, Wang J, Ni J, Ding Y, Wang S, Yin J, Ding L, Ran X, Fan S, Sun Q, Tan SY, Koeffler HP, Li J, Mi Y, Chen YQ
International journal of biological macromolecules 2024 Oct;278(Pt 3):134844
International journal of biological macromolecules 2024 Oct;278(Pt 3):134844
Dipeptidyl peptidase 4: A predictor of ferroptosis in ulcerative colitis.
Zhu F, Zou D, Shi P, Tang L, Wu D, Hu X, Yin F, Liu J
The journal of gene medicine 2024 Oct;26(10):e3742
The journal of gene medicine 2024 Oct;26(10):e3742
Global acetylome profiling indicates EPA impedes but OA promotes prostate cancer motility through altered acetylation of PFN1 and FLNA.
He C, Chen X, Chen Y, Sun J, Qi M, Rocha S, Wang M
Proteomics 2024 Oct;24(19):e2300393
Proteomics 2024 Oct;24(19):e2300393
ITCH inhibits alkaliptosis in human pancreatic cancer cells through YAP1-dependent SLC16A1 activation.
Cai X, Chen F, Tang H, Chao D, Kang R, Tang D, Liu J
The international journal of biochemistry & cell biology 2024 Oct;175:106646
The international journal of biochemistry & cell biology 2024 Oct;175:106646
Acovenosigenin A β-glucoside mediates JAK2-STAT3 signaling pathway by targeting GP130 in A549 and H460 cells based on integrative analysis of transcriptome and proteome and biological verification.
Liu Z, Wang Q, Chi Y, Chen R, Zhao L, Liu Z, Zhai J, Li S, Han N, Yin J
Bioorganic chemistry 2024 Oct;151:107633
Bioorganic chemistry 2024 Oct;151:107633
Paeoniflorin suppresses ferroptosis after traumatic brain injury by antagonizing P53 acetylation.
Zhi SM, Cui Y, Liu Y, Zhang JT, Li XJ, Sheng B, Chen XX, Yan CL, Li W, Mao JN, Yan HY, Jin W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155940
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155940
Effect of dapagliflozin on pulmonary vascular remodeling in rats with chronic hypoxic pulmonary arterial hypertension.
Xu Y, Liang W, Huo J, Zhang T, Feng T, Li M, Zhu Z, Zhou P, Zhu S, Lu Y, Wang L
Journal of receptor and signal transduction research 2024 Oct-Dec;44(5-6):174-180
Journal of receptor and signal transduction research 2024 Oct-Dec;44(5-6):174-180
Astaxanthin Alleviates Chronic Prostatitis via the ERK1/2 Signaling Pathway: Evidence from Network Pharmacology and Experimental Validation.
Liu Y, Huang L, Zhang Z, Zhu Q, Xi P, Sun T, Gong B
Combinatorial chemistry & high throughput screening 2024 Oct 9;
Combinatorial chemistry & high throughput screening 2024 Oct 9;
Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation.
Delgado T, Emerson J, Hong M, Keillor JW, Johnson GV
bioRxiv : the preprint server for biology 2024 Oct 31;
bioRxiv : the preprint server for biology 2024 Oct 31;
Increased expression of mesencephalic astrocyte-derived neurotrophic factor (MANF) contributes to synapse loss in Alzheimer's disease.
Zhang Y, Chen X, Chen L, Shao M, Zhu W, Xing T, Guo T, Jia Q, Yang H, Yin P, Yan XX, Yu J, Li S, Li XJ, Yang S
Molecular neurodegeneration 2024 Oct 18;19(1):75
Molecular neurodegeneration 2024 Oct 18;19(1):75
Exogenous hydrogen sulfide enhances myogenic differentiation of C2C12 myoblasts under high palmitate stress.
Lu F, Zhang S, Dong S, Wang M, Pang K, Zhao Y, Huang J, Kang J, Liu N, Zhang X, Zhao D, Lu F, Zhang W
Heliyon 2024 Oct 15;10(19):e38661
Heliyon 2024 Oct 15;10(19):e38661
Discovery of Potent Covalent CRM1 Inhibitors Via a Customized Structure-Based Virtual Screening Pipeline and Bioassays.
Liu H, Shen C, Li H, Hou T, Yang Y
Journal of chemical information and modeling 2024 Oct 14;64(19):7422-7431
Journal of chemical information and modeling 2024 Oct 14;64(19):7422-7431
Discovery of SIRT1-Activating Hydrogen Sulfide Donating Derivatives for Efficient Resistant of Myocardial Ischemic Injury.
Wang S, Feng D, Wang W, Zheng C, Liang C, Li S, Li H, Xu F, Cao H, Hua H, Cheng M, Li D
Journal of medicinal chemistry 2024 Oct 10;67(19):17657-17675
Journal of medicinal chemistry 2024 Oct 10;67(19):17657-17675
A comprehensive analysis of CEBPA on prognosis and function in uterine corpus endometrial carcinoma.
Wang J, Huang W, Chai S, Gan J, Zeng Y, Long P, Pang L
Scientific reports 2024 Oct 10;14(1):23773
Scientific reports 2024 Oct 10;14(1):23773
The LncRNA6524/miR-92a-2-5p/Dvl1/Wnt/β-catenin axis promotes renal fibrosis in the UUO mouse model.
Xie Y, Zhang G, Pan J, Qiu S, Zhang D
Archives of biochemistry and biophysics 2024 Nov;761:110175
Archives of biochemistry and biophysics 2024 Nov;761:110175
miR‑155 promotes an inflammatory response in HaCaT cells via the IRF2BP2/KLF2/NF‑κB pathway in psoriasis.
Chen L, Liu C, Xiang X, Qiu W, Guo K
International journal of molecular medicine 2024 Nov;54(5)
International journal of molecular medicine 2024 Nov;54(5)
FOXO1-mTOR pathway in vascular pericyte regulates the formation of type H vessels to control bone metabolism.
Cheng C, Deng M, Cheng C, Wu H, Wang Y, Lu M, Yao Z, Li K, Zhang X, Yu B
Journal of orthopaedic translation 2024 Nov;49:246-263
Journal of orthopaedic translation 2024 Nov;49:246-263
GTF2H5 Identified as a crucial synthetic lethal target to counteract chemoresistance in colorectal cancer.
Nie J, Liu X, Xu M, Chen X, Hu S, Gu X, Sun H, Gao T, Pan Y, Wang S
Translational oncology 2024 Nov;49:102097
Translational oncology 2024 Nov;49:102097
PDZD8 Augments Endoplasmic Reticulum-Mitochondria Contact and Regulates Ca2+ Dynamics and Cypd Expression to Induce Pancreatic β-Cell Death during Diabetes.
Liu Y, Wei Y, Jin X, Cai H, Chen Q, Zhang X
Diabetes & metabolism journal 2024 Nov;48(6):1058-1072
Diabetes & metabolism journal 2024 Nov;48(6):1058-1072
A two-pronged approach to inhibit ferroptosis of MSCs caused by the iron overload in postmenopausal osteoporosis and promote osseointegration of titanium implant.
Yang Y, Zhang X, Yang Y, Gao P, Fan W, Zheng T, Yang W, Tang Y, Cai K
Bioactive materials 2024 Nov;41:336-354
Bioactive materials 2024 Nov;41:336-354
Prevotella melaninogenica disrupted oral epithelial barrier function via myosin light chain kinase.
Guo Y, Han W, He Y
Oral diseases 2024 Nov;30(8):5102-5112
Oral diseases 2024 Nov;30(8):5102-5112
Protective effects of bioactive components targeting β2-adrenergic receptors and muscarinic-3 acetylcholine receptor in Zhisou San on ovalbumin-induced allergic asthma.
Li FW, Zhou N, Li JJ, Zhang YJ, Zhao X
Journal of Asian natural products research 2024 Nov;26(11):1358-1373
Journal of Asian natural products research 2024 Nov;26(11):1358-1373
Mesenchymal stem cells improve depressive disorder via inhibiting the inflammatory polarization of microglia.
Wang Q, Xu Y, Zhu S, Jiang L, Yao L, Yu X, Zhang Y, Jia S, Hong M, Zheng J
Journal of psychiatric research 2024 Nov;179:105-116
Journal of psychiatric research 2024 Nov;179:105-116
Accelerating diabetic wound healing with Ramulus Mori (Sangzhi) alkaloids via NRF2/HO-1/eNOS pathway.
Xiao F, Rui S, Zhang X, Ma Y, Wu X, Hao W, Huang G, Armstrong DG, Chen Q, Deng W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155990
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155990
S. glabra exerts anti-lung cancer effects by inducing ferroptosis and anticancer immunity.
Liu S, Zhang L, Ding K, Zeng B, Li B, Zhou J, Li J, Wang J, Zhang H, Sun R, Su X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155981
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155981
Trans-resveratrol mitigates miR-204-3p mediated progression of allergic rhinitis by regulating the EGLN3/HIF-1α/IL33/ST2 signalling pathway.
Mao W, Wang B, Chen F, Luo D, Li Y, Liu Y, Liu Y, Dong P, Huang R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155967
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155967
HES1 revitalizes the functionality of aged adipose-derived stem cells by inhibiting the transcription of STAT1.
Li C, Ren S, Yan C, Wang C, Jiang T, Kang Y, Chen J, Xiong H, Guo J, Jiang G, Liu S, Nie P, Chen Z
Stem cell research & therapy 2024 Nov 5;15(1):399
Stem cell research & therapy 2024 Nov 5;15(1):399
Involvement of sphingosine-1-phosphate receptor 1 in pain insensitivity in a BTBR mouse model of autism spectrum disorder.
Fan L, Li Q, Shi Y, Li X, Liu Y, Chen J, Sun Y, Chen A, Yang Y, Zhang X, Wang J, Wu L
BMC medicine 2024 Nov 4;22(1):504
BMC medicine 2024 Nov 4;22(1):504
Oxidative Injury to Lung Mitochondrial DNA is a Key Contributor for the Development of Chemical Lung Injury.
Dubey S, Yu Z, Stephens EM, Lazrak A, Ahmad I, Aggarwal S, Andrabi S, Hossain MI, Jilling T, Fernadez SR, Bartels JL, Lapi SE, Mobley J, Pastukh VM, Gillespie M, Matalon S
bioRxiv : the preprint server for biology 2024 Nov 25;
bioRxiv : the preprint server for biology 2024 Nov 25;
KLF4 promotes cisplatin resistance by activating mTORC1 signaling in ovarian cancer.
Zhou W, Huang H, Teng Y, Hua R, Hu Y, Li X
Discover oncology 2024 Nov 20;15(1):682
Discover oncology 2024 Nov 20;15(1):682
A novel multifunctional nanocomposite hydrogel orchestrates the macrophage reprogramming-osteogenesis crosstalk to boost bone defect repair.
Wang Y, Chen Y, Zhou T, Li J, Zhang N, Liu N, Zhou P, Mao Y
Journal of nanobiotechnology 2024 Nov 13;22(1):702
Journal of nanobiotechnology 2024 Nov 13;22(1):702
Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation.
Delgado T, Emerson J, Hong M, Keillor JW, Johnson GV
bioRxiv : the preprint server for biology 2024 Nov 11;
bioRxiv : the preprint server for biology 2024 Nov 11;
A peptide against the N-terminus of myristoylated alanine-rich C kinase substrate promotes neuronal differentiation in SH-SY5Y human neuroblastoma cells.
Ferdous J, Naitou K, Shiraishi M
The Journal of veterinary medical science 2024 Nov 1;86(11):1136-1144
The Journal of veterinary medical science 2024 Nov 1;86(11):1136-1144
Itaconate inhibits corticosterone-induced necroptosis and neuroinflammation via up-regulating menin in HT22 cells.
Liang JY, Gao S, Jiang JM, Zhang P, Zou W, Tang XQ, Tang YY
Journal of physiology and biochemistry 2024 May;80(2):393-405
Journal of physiology and biochemistry 2024 May;80(2):393-405
PMP2 regulates myelin thickening and ATP production during remyelination.
Hong J, Garfolo R, Kabre S, Humml C, Velanac V, Roué C, Beck B, Jeanette H, Haslam S, Bach M, Arora S, Acheta J, Nave KA, Schwab MH, Jourd'heuil D, Poitelon Y, Belin S
Glia 2024 May;72(5):885-898
Glia 2024 May;72(5):885-898
ER-tethered RNA-binding protein controls NADPH oxidase translation for hydrogen peroxide homeostasis.
Pei X, Wang Z, He W, Li S, Chen X, Fan Z, Lan Y, Yuan L, Xu P
Redox biology 2024 May;71:103126
Redox biology 2024 May;71:103126
EMX2 inhibits clear cell renal cell carcinoma progress via modulating Akt/FOXO3a pathway.
Zhou X, Dong S, Zhou Y, He Z, Zhang Z, Liao L, Zou B, Zheng X, Peng K, Duan X
Molecular carcinogenesis 2024 May;63(5):951-961
Molecular carcinogenesis 2024 May;63(5):951-961
Follicular fluid-derived exosomal LncRNA LIPE-AS1 modulates steroid metabolism and survival of granulosa cells leading to oocyte maturation arrest in polycystic ovary syndrome.
Yu L, Wang C, Liu M, Xia L, Liu T, Che Q, Cai W, Dong X, Pan B, Wang B, Liu S, Guo W
Journal of assisted reproduction and genetics 2024 May;41(5):1387-1401
Journal of assisted reproduction and genetics 2024 May;41(5):1387-1401
PLCE1 enhances mitochondrial dysfunction to promote GSDME-mediated pyroptosis in doxorubicin-induced cardiotoxicity.
Tuersuntuoheti M, Peng F, Li J, Zhou L, Gao H, Gong H
Biochemical pharmacology 2024 May;223:116142
Biochemical pharmacology 2024 May;223:116142
D-mannose alleviates intervertebral disc degeneration through glutamine metabolism.
Dong ZL, Jiao X, Wang ZG, Yuan K, Yang YQ, Wang Y, Li YT, Wang TC, Kan TY, Wang J, Tao HR
Military Medical Research 2024 May 6;11(1):28
Military Medical Research 2024 May 6;11(1):28
PD-1/PD-L1 axis is involved in the interaction between microglial polarization and glioma.
Wang XP, Guo W, Chen YF, Hong C, Ji J, Zhang XY, Dong YF, Sun XL
International immunopharmacology 2024 May 30;133:112074
International immunopharmacology 2024 May 30;133:112074
Electroacupuncture modulates the TLR4-NF-κB inflammatory signaling pathway to attenuate ocular surface inflammation in dry eyes of type 2 diabetic rats.
Fu Z, Wan M, Jin T, Lai S, Li X, Sun X, Gao W
Cellular and molecular biology (Noisy-le-Grand, France) 2024 May 27;70(5):111-118
Cellular and molecular biology (Noisy-le-Grand, France) 2024 May 27;70(5):111-118
Nitazoxanide protects against experimental ulcerative colitis through improving intestinal barrier and inhibiting inflammation.
Zhu HT, Luo J, Peng Y, Cheng XF, Wu SZ, Zhao YD, Chang L, Sun ZJ, Dong DL
Chemico-biological interactions 2024 May 25;395:111013
Chemico-biological interactions 2024 May 25;395:111013
Transcriptomics confirms IRF1 as a key regulator of pyroptosis in diabetic retinopathy.
Xian Y, Wang X, Yu Y, Chen X
Biochemical and biophysical research communications 2024 May 21;709:149760
Biochemical and biophysical research communications 2024 May 21;709:149760
Targeted degradation of oncogenic BCR-ABL by silencing the gene of NEDD8 E3 ligase RAPSYN.
Sun Y, Wang Y, Liu C, Huang Y, Long Q, Ju C, Zhang C, Chen Y
Journal of nanobiotechnology 2024 May 13;22(1):247
Journal of nanobiotechnology 2024 May 13;22(1):247
Oxypeucedanin hydrate alleviates rheumatoid arthritis by inhibiting the TLR4-MD2/NF-κB/MAPK signaling axis.
Liu M, Huo X, Li C, Hu Y, Lei H, Wang D, Zhu L, Gu Y, Guo D, Huang L, Deng Y
Acta biochimica et biophysica Sinica 2024 May 11;56(12):1789-1801
Acta biochimica et biophysica Sinica 2024 May 11;56(12):1789-1801
Esculin suppresses the PERK-eIF2α-CHOP pathway by enhancing SIRT1 expression in oxidative stress-induced rat chondrocytes, mitigating osteoarthritis progression in a rat model.
Cheng Z, Liu Z, Liu C, Yang A, Miao H, Bai X
International immunopharmacology 2024 May 10;132:112061
International immunopharmacology 2024 May 10;132:112061
The disrupting effect of chlormequat chloride on growth hormone is associated with pregnancy.
Wu Z, Ma L, Su D, Xiagedeer B
Toxicology letters 2024 May 1;395:17-25
Toxicology letters 2024 May 1;395:17-25
Crocin Inhibits Orbital Fibroblasts Fibrosis in Thyroid-Associated Ophthalmopathy.
Xu S, Mao H
Current eye research 2024 Mar;49(3):330-337
Current eye research 2024 Mar;49(3):330-337
SESN1 functions as a new tumor suppressor gene via Toll-like receptor signaling pathway in neuroblastoma.
Hua Z, Chen B, Gong B, Lin M, Ma Y, Li Z
CNS neuroscience & therapeutics 2024 Mar;30(3):e14664
CNS neuroscience & therapeutics 2024 Mar;30(3):e14664
OTUD7B knockdown inhibits the proliferation and stemness of breast cancer cells by destabilizing FOXM1.
Wang H, Han S, Xiao J, Fu X, Chen W, Zhuo D
Oncology letters 2024 Mar;27(3):102
Oncology letters 2024 Mar;27(3):102
ACOX1 deficiency-induced lipid metabolic disorder facilitates chronic interstitial fibrosis development in renal allografts.
Zhang YH, Bin Liu, Meng Q, Zhang D, Yang H, Li G, Wang Y, Liu M, Liu N, Yu J, Liu S, Zhou H, Xu ZX, Wang Y
Pharmacological research 2024 Mar;201:107105
Pharmacological research 2024 Mar;201:107105
RSK4 promotes the macrophage recruitment and M2 polarization in esophageal squamous cell carcinoma.
He S, Lu M, Zhang L, Wang Z
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166996
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166996
Enhanced glutathione production protects against zearalenone-induced oxidative stress and ferroptosis in female reproductive system.
Fu W, Dai C, Ma Z, Li Q, Lan D, Sun C, Wu X, Li J, Wang S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Mar;185:114462
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Mar;185:114462
DTTZ suppresses ferroptosis and reverses mitochondrial dysfunction in normal tissues affected by chemotherapy.
Yang Y, Chen Y, Tang H, Zhang Z, Zhou X, Xu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116227
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116227
Genome-wide analyses reveal the regulatory roles of DNA methylation-regulated alternative promoter transcripts in breast cancer.
Song Y, Shen T, Sun H, Wang X
Human genetics 2024 Mar;143(3):385-399
Human genetics 2024 Mar;143(3):385-399
The RNA m(6)A reader IGF2BP3 regulates NFAT1/IRF1 axis-mediated anti-tumor activity in gastric cancer.
Ge L, Rui Y, Wang C, Wu Y, Wang H, Wang J
Cell death & disease 2024 Mar 6;15(3):192
Cell death & disease 2024 Mar 6;15(3):192
Pan-cancer integrated analysis of ANKRD1 expression, prognostic value, and potential implications in cancer.
Xu X, Zhong D, Wang X, Luo F, Zheng X, Feng T, Chen R, Cheng Y, Wang Y, Ma G
Scientific reports 2024 Mar 4;14(1):5268
Scientific reports 2024 Mar 4;14(1):5268
RFX1 regulates foam cell formation and atherosclerosis by mediating CD36 expression.
Yang S, Min X, Hu L, Zheng M, Lu S, Zhao M, Jia S
International immunopharmacology 2024 Mar 30;130:111751
International immunopharmacology 2024 Mar 30;130:111751
Discovery and verification of mmu_Circ_26986/hsa_Circ_0072463 as a potential biomarker and intervention target for sepsis-associated acute kidney injury.
Peng X, Li H, Zhang W, Zhang D
Cellular and molecular life sciences : CMLS 2024 Mar 28;81(1):154
Cellular and molecular life sciences : CMLS 2024 Mar 28;81(1):154
Securin acetylation prevents precocious separase activation and premature sister chromatid separation.
Wang T, Zou Y, Meng H, Zheng P, Teng J, Huang N, Chen J
Current biology : CB 2024 Mar 25;34(6):1295-1308.e5
Current biology : CB 2024 Mar 25;34(6):1295-1308.e5
Piperine promotes PI3K/AKT/mTOR-mediated gut-brain autophagy to degrade α-Synuclein in Parkinson's disease rats.
Yu L, Hu X, Xu R, Zhao Y, Xiong L, Ai J, Wang X, Chen X, Ba Y, Xing Z, Guo C, Mi S, Wu X
Journal of ethnopharmacology 2024 Mar 25;322:117628
Journal of ethnopharmacology 2024 Mar 25;322:117628
An intranasal influenza virus vector vaccine protects against Helicobacter pylori in mice.
Nie L, Huang Y, Cheng Z, Luo H, Zhan Y, Dou K, Ma C, Yu C, Luo C, Liu Z, Liu S, Zhu Y
Journal of virology 2024 Mar 19;98(3):e0192323
Journal of virology 2024 Mar 19;98(3):e0192323
Metformin switches cell death modes to soothe the apical periodontitis via ZBP1.
Liu H, Liu YX, Fan W, Fan B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23549
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23549
YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia.
Liu Z, Li S, Chen S, Sheng J, Li Z, Lv T, Yu W, Fan Y, Wang J, Liu W, Hu S, Jin J
iScience 2024 Mar 15;27(3):109125
iScience 2024 Mar 15;27(3):109125
Design, synthesis, and bioactivity evaluation of novel indole-selenide derivatives as P-glycoprotein inhibitors against multi-drug resistance in MCF-7/ADR cell.
Yang Z, Luo D, Shao C, Hu H, Yang X, Cai Y, Mou X, Wu Q, Xu H, Sun X, Wang H, Hou W
European journal of medicinal chemistry 2024 Mar 15;268:116207
European journal of medicinal chemistry 2024 Mar 15;268:116207
Endoplasmic reticulum stress impedes regulated secretion by governing key exocytotic and granulogenic molecular switches.
Mukherjee M, Mukherjee C, Ghosh V, Jain A, Sadhukhan S, Dagar S, Sahu BS
Journal of cell science 2024 Mar 15;137(6)
Journal of cell science 2024 Mar 15;137(6)
Antidepressant fluoxetine alleviates colitis by reshaping intestinal microenvironment.
Teng S, Yang Y, Zhang W, Li X, Li W, Cui Z, Min L, Wu J
Cell communication and signaling : CCS 2024 Mar 12;22(1):176
Cell communication and signaling : CCS 2024 Mar 12;22(1):176
Mefloquine enhances the efficacy of anti-PD-1 immunotherapy via IFN-γ-STAT1-IRF1-LPCAT3-induced ferroptosis in tumors.
Tao Q, Liu N, Wu J, Chen J, Chen X, Peng C
Journal for immunotherapy of cancer 2024 Mar 11;12(3)
Journal for immunotherapy of cancer 2024 Mar 11;12(3)
IL-35 ameliorates lipopolysaccharide-induced endothelial dysfunction by inhibiting endothelial-to-mesenchymal transition.
Feng J, Li K, Xie F, Han L, Wu Y
International immunopharmacology 2024 Mar 10;129:111567
International immunopharmacology 2024 Mar 10;129:111567
The mechanism of EGFL7 regulating neovascularization in diabetic retinopathy through the PI3K/AKT/VEGFA pathway.
Xian Y, Wang X, Yu Y, Chen X
Life sciences 2024 Mar 1;340:122483
Life sciences 2024 Mar 1;340:122483
Arecoline induces neurotoxicity in HT22 cells via the promotion of endoplasmic reticulum stress and downregulation of the Nrf2/HO-1 pathway.
Yan H, Ding J, Li X, Li S, Zhang D
Environmental toxicology 2024 Jun;39(6):3410-3424
Environmental toxicology 2024 Jun;39(6):3410-3424
LUC7L3 is a downstream factor of SRSF1 and prevents genomic instability.
Zhang X, Guo J, Shi X, Zhou X, Chen Q
Cell insight 2024 Jun;3(3):100170
Cell insight 2024 Jun;3(3):100170
Real time monitoring peripheral nerve function with ICG and BDA-ICG by NIR-II fluorescence imaging.
Yang X, Wang Y, Qu C, Tan B, Wang M, Li S, Huang J, Li J, Fang M, Cheng Z, Zhou N
Materials today. Bio 2024 Jun;26:101084
Materials today. Bio 2024 Jun;26:101084
Conditional deficiency of Rho-associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice.
Akamine T, Terabayashi T, Sasaki T, Hayashi R, Abe I, Hirayama F, Nureki SI, Ikawa M, Miyata H, Tokunaga A, Kobayashi T, Hanada K, Thumkeo D, Narumiya S, Ishizaki T
FEBS open bio 2024 Jun;14(6):906-921
FEBS open bio 2024 Jun;14(6):906-921
HOXB2 promotes cisplatin resistance by upregulating lncRNA DANCR in ovarian cancer.
Li X, Zheng Z, Zhou W, Huang H, Zhou Y, Xu Q, Zhu X, Teng Y
Journal of ovarian research 2024 Jun 8;17(1):124
Journal of ovarian research 2024 Jun 8;17(1):124
Bu-Shen-Ning-Xin decoction inhibits macrophage activation to ameliorate premature ovarian insufficiency-related osteoimmune disorder via FSH/FSHR pathway.
Sun H, Qi Q, Pan X, Zhou J, Wang J, Li L, Li D, Wang L
Drug discoveries & therapeutics 2024 Jun 6;18(2):106-116
Drug discoveries & therapeutics 2024 Jun 6;18(2):106-116
Increasing GSH-Px Activity and Activating Wnt Pathway Promote Fine Wool Growth in FGF5-Edited Sheep.
Xu XL, Wu SJ, Qi SY, Chen MM, Liu ZM, Zhang R, Zhao Y, Liu SQ, Zhou WD, Zhang JL, Zhang XS, Deng SL, Yu K, Li Y, Lian ZX
Cells 2024 Jun 5;13(11)
Cells 2024 Jun 5;13(11)
A pan-KRAS degrader for the treatment of KRAS-mutant cancers.
Yang J, Wang QL, Wang GN, Ye JC, Li ZQ, Wang JY, Liang ZH, Li SX, Sun C, Liao WT, Gao YJ, Wang J, Mao Y, Yu C, Feng GK, Zeng MS
Cell discovery 2024 Jun 28;10(1):70
Cell discovery 2024 Jun 28;10(1):70
Tumor cell-released autophagosomes (TRAPs) induce PD-L1-decorated NETs that suppress T-cell function to promote breast cancer pulmonary metastasis.
Zhou X, Wu C, Wang X, Pan N, Sun X, Chen B, Zheng S, Wei Y, Chen J, Wu Y, Zhu F, Chen J, Chen H, Wang LX
Journal for immunotherapy of cancer 2024 Jun 26;12(6)
Journal for immunotherapy of cancer 2024 Jun 26;12(6)
PWP1 is overexpressed in hepatocellular carcinoma and facilitates liver cancer cell proliferation.
Huang R, Xu F, Su L, Lu Y, Liu W, Liu S, Yang L, Su L, Song W
Heliyon 2024 Jun 15;10(11):e32409
Heliyon 2024 Jun 15;10(11):e32409
Frataxin deficiency shifts metabolism to promote reactive microglia via glucose catabolism.
Sciarretta F, Zaccaria F, Ninni A, Ceci V, Turchi R, Apolloni S, Milani M, Della Valle I, Tiberi M, Chiurchiù V, D'Ambrosi N, Pedretti S, Mitro N, Volontè C, Amadio S, Aquilano K, Lettieri-Barbato D
Life science alliance 2024 Jul;7(7)
Life science alliance 2024 Jul;7(7)
NKAIN1, as an oncogene, promotes the proliferation and metastasis of breast cancer, affecting its prognosis.
Wang X, Yang F, Sun Z, Zhao G, Pu Q, Geng C, Dong K, Zhang X, Liu Z, Song H
Molecular carcinogenesis 2024 Jul;63(7):1392-1405
Molecular carcinogenesis 2024 Jul;63(7):1392-1405
Transformation of A1/A2 Astrocytes Participates in Brain Ischemic Tolerance Induced by Cerebral Ischemic Preconditioning via Inhibiting NDRG2.
Liu XH, Zhang LY, Liu XY, Zhang JG, Hu YY, Zhao CG, Xian XH, Li WB, Zhang M
Neurochemical research 2024 Jul;49(7):1665-1676
Neurochemical research 2024 Jul;49(7):1665-1676
Quercetin prevented diabetic nephropathy by inhibiting renal tubular epithelial cell apoptosis via the PI3K/AKT pathway.
Liu F, Feng Q, Yang M, Yang Y, Nie J, Wang S
Phytotherapy research : PTR 2024 Jul;38(7):3594-3606
Phytotherapy research : PTR 2024 Jul;38(7):3594-3606
MicroRNA-322-5p targeting Smurf2 regulates the TGF-β/Smad pathway to protect cardiac function and inhibit myocardial infarction.
Guo L, Li K, Ma Y, Niu H, Li J, Shao X, Li N, Sun Y, Wang H
Human cell 2024 Jul;37(4):972-985
Human cell 2024 Jul;37(4):972-985
PPARα phosphorylation regulates colorectal tumor immune escape.
Gou Q, Tian X, Dong C, Yan B, Chen M, Shi J, Yang L, Hou Y
The Journal of biological chemistry 2024 Jul;300(7):107447
The Journal of biological chemistry 2024 Jul;300(7):107447
PC (16:0/14:0) ameliorates hyperoxia-induced bronchopulmonary dysplasia by upregulating claudin-1 and promoting alveolar type II cell repair.
Hou W, Yu B, Li Y, Yan X, Su Q, Fang X, Zhou X, Yu Z
The international journal of biochemistry & cell biology 2024 Jul;172:106587
The international journal of biochemistry & cell biology 2024 Jul;172:106587
Preventive effect of propolis on cognitive decline in Alzheimer's disease model mice.
Inagaki R, Yamakuni T, Saito T, Saido TC, Moriguchi S
Neurobiology of aging 2024 Jul;139:20-29
Neurobiology of aging 2024 Jul;139:20-29
The EPRS-ATF4-COLI pathway axis is a potential target for anaplastic thyroid carcinoma therapy.
Mi L, Liu J, Zhang Y, Su A, Tang M, Xing Z, He T, Wei T, Li Z, Wu W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155670
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155670
Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation.
Isei MO, Crockett M, Chen E, Rodwell-Bullock J, Caroll T, Girardi PA, Nehrke K, Johnson GV
bioRxiv : the preprint server for biology 2024 Jul 9;
bioRxiv : the preprint server for biology 2024 Jul 9;
Alcohol- and Low-Iron Induced Changes in Antioxidant and Energy Metabolism Associated with Protein Lys Acetylation.
Thornton JA, Koc ZC, Sollars VE, Valentovic MA, Denvir J, Wilkinson J 4th, Koc EC
International journal of molecular sciences 2024 Jul 30;25(15)
International journal of molecular sciences 2024 Jul 30;25(15)
Lipid-associated macrophages reshape BAT cell identity in obesity.
Sciarretta F, Ninni A, Zaccaria F, Chiurchiù V, Bertola A, Karlinsey K, Jia W, Ceci V, Di Biagio C, Xu Z, Gaudioso F, Tortolici F, Tiberi M, Zhang J, Carotti S, Boudina S, Grumati P, Zhou B, Brestoff JR, Ivanov S, Aquilano K, Lettieri-Barbato D
Cell reports 2024 Jul 23;43(7):114447
Cell reports 2024 Jul 23;43(7):114447
Procyanidin C1 inhibits bleomycin-induced pulmonary fibrosis in mice by selective clearance of senescent myofibroblasts.
Shao M, Qiu Y, Shen M, Liu W, Feng D, Luo Z, Zhou Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23749
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23749
Initial Characterization of WDR5B Reveals a Role in the Proliferation of Retinal Pigment Epithelial Cells.
Bailey JK, Ma D, Clegg DO
Cells 2024 Jul 13;13(14)
Cells 2024 Jul 13;13(14)
Genome-scale exon perturbation screens uncover exons critical for cell fitness.
Xiao MS, Damodaran AP, Kumari B, Dickson E, Xing K, On TA, Parab N, King HE, Perez AR, Guiblet WM, Duncan G, Che A, Chari R, Andresson T, Vidigal JA, Weatheritt RJ, Aregger M, Gonatopoulos-Pournatzis T
Molecular cell 2024 Jul 11;84(13):2553-2572.e19
Molecular cell 2024 Jul 11;84(13):2553-2572.e19
Synthesis and Characterization of a Novel PET Tracer for Noninvasive Evaluation of FGL1 Status in Tumors.
Tan S, Ding X, Pan D, Xu Y, Wang C, Yan J, Chen C, Wang L, Wang X, Yang M, Xu Y
Molecular pharmaceutics 2024 Jul 1;21(7):3425-3433
Molecular pharmaceutics 2024 Jul 1;21(7):3425-3433
Circular RNA circXPO1 Promotes Multiple Myeloma Progression by Regulating miR-495-3p/DNA Damage-Induced Transcription 4 Axis.
Li F, Liu J, Miao J, Hong F, Liu R, Lv Y, Yang Y, He A, Wang J
DNA and cell biology 2024 Jan;43(1):39-55
DNA and cell biology 2024 Jan;43(1):39-55
Aristolochic acid I aggravates oxidative stress-mediated apoptosis by inhibiting APE1/Nrf2/HO-1 signaling.
Zhang Q, Tian L, Hu Y, Jiang W, Wang X, Chen L, Cheng S, Ying J, Jiang B, Zhang L
Toxicology mechanisms and methods 2024 Jan;34(1):20-31
Toxicology mechanisms and methods 2024 Jan;34(1):20-31
HSP90β regulates EAAT2 expression and participates in ischemia‑reperfusion injury in rats.
Liang T, Hu X, Zeng L, Zhou Z, Zhang J, Xu Z, Zeng J, Xu P
Molecular medicine reports 2024 Jan;29(1)
Molecular medicine reports 2024 Jan;29(1)
Ailanthone synergizes with PARP1 inhibitor in tumour growth inhibition through crosstalk of DNA repair pathways in gastric cancer.
Wang C, Yi T, Li X, Cui J, Li B, Qin Y, Tang S, Zhang J
Journal of cellular and molecular medicine 2024 Jan;28(2):e18033
Journal of cellular and molecular medicine 2024 Jan;28(2):e18033
Identification of potential miR‑155 target genes in epidermal immune microenvironment of atopic dermatitis patients and their inflammatory effects on HaCaT cells.
Wang X, Chen L, Chen X, Liu C, Qiu W, Guo K
Experimental and therapeutic medicine 2024 Jan;27(1):25
Experimental and therapeutic medicine 2024 Jan;27(1):25
MicroRNA-124 conducts neuroprotective effect via inhibiting AK4/ATF3 after subarachnoid hemorrhage.
Jiang W, Jia Q, Ma H, Han S, Bi S, Zhu K, Chen L, Liang G
Experimental brain research 2024 Jan;242(1):33-45
Experimental brain research 2024 Jan;242(1):33-45
Hydrogen sulfide attenuates depression-like behaviours in Parkinson's disease model rats by improving synaptic plasticity in a hippocampal Warburg effect-dependent manner.
Liu F, Tian Q, Tang HL, Cheng X, Zou W, Zhang P
Pharmacology, biochemistry, and behavior 2024 Jan;234:173677
Pharmacology, biochemistry, and behavior 2024 Jan;234:173677
Amyloid pathology reduces ELP3 expression and tRNA modifications leading to impaired proteostasis.
Pereira M, Ribeiro DR, Berg M, Tsai AP, Dong C, Nho K, Kaiser S, Moutinho M, Soares AR
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166857
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166857
Inulin alters gut microbiota to alleviate post-stroke depressive-like behavior associated with the IGF-1-mediated MAPK signaling pathway.
Shao R, Tan X, Pan M, Huang J, Huang L, Bi B, Huang X, Wang J, Li X
Brain and behavior 2024 Jan;14(1):e3387
Brain and behavior 2024 Jan;14(1):e3387
Lycopene protects against ionizing radiation-induced testicular damage by inhibition of apoptosis and mitochondrial dysfunction.
Qu M, He Q, Guo B
Food science & nutrition 2024 Jan;12(1):534-546
Food science & nutrition 2024 Jan;12(1):534-546
Mitochondria-derived peptide is an effective target for treating streptozotocin induced painful diabetic neuropathy through induction of activated protein kinase/peroxisome proliferator-activated receptor gamma coactivator 1alpha -mediated mitochondrial biogenesis.
Xu L, Tang X, Yang L, Chang M, Xu Y, Chen Q, Lu C, Liu S, Jiang J
Molecular pain 2024 Jan-Dec;20:17448069241252654
Molecular pain 2024 Jan-Dec;20:17448069241252654
High-fat diet-induced L-saccharopine accumulation inhibits estradiol synthesis and damages oocyte quality by disturbing mitochondrial homeostasis.
Wen J, Feng Y, Xue L, Yuan S, Chen Q, Luo A, Wang S, Zhang J
Gut microbes 2024 Jan-Dec;16(1):2412381
Gut microbes 2024 Jan-Dec;16(1):2412381
Varicella zoster virus glycoprotein E facilitates PINK1/Parkin-mediated mitophagy to evade STING and MAVS-mediated antiviral innate immunity.
Oh SJ, Yu JW, Ahn JH, Choi ST, Park H, Yun J, Shin OS
Cell death & disease 2024 Jan 6;15(1):16
Cell death & disease 2024 Jan 6;15(1):16
TBC1D1 represses glioma progression by altering the integrity of the cytoskeleton.
Cai J, Jiang Y, Chen P, Liang J, Zhang Y, Yuan R, Fan H, Zhong Y, Cai J, Cheng S, Zhang Y
Aging 2024 Jan 5;16(1):431-444
Aging 2024 Jan 5;16(1):431-444
α-Synuclein reduces acetylserotonin O-methyltransferase mediated melatonin biosynthesis by microtubule-associated protein 1 light chain 3 beta-related degradation pathway.
Jia C, Tian L, Cheng C, Zhang J, Al-Nusaif M, Li T, Yang H, Lin Y, Li S, Le W
Cellular and molecular life sciences : CMLS 2024 Jan 27;81(1):61
Cellular and molecular life sciences : CMLS 2024 Jan 27;81(1):61
FBXO28 promotes cell proliferation, migration and invasion via upregulation of the TGF-beta1/SMAD2/3 signaling pathway in ovarian cancer.
Song G, Sun Z, Chu M, Zhang Z, Chen J, Wang Z, Zhu X
BMC cancer 2024 Jan 24;24(1):122
BMC cancer 2024 Jan 24;24(1):122
DDX60 Promotes Migration and Invasion of Head and Neck Squamous Cell Carcinoma Cell through the NF-κB/IFI27 Signaling Pathway.
Han Y, Gao J, Liu L
Frontiers in bioscience (Landmark edition) 2024 Jan 17;29(1):14
Frontiers in bioscience (Landmark edition) 2024 Jan 17;29(1):14
Discovery of (quinazolin-6-yl)benzamide derivatives containing a 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety as potent reversal agents against P-glycoprotein-mediated multidrug resistance.
Xue WH, Liu KL, Zhang TJ, Dong G, Wang JH, Wang J, Guo S, Hu J, Zhang QY, Li XY, Meng FH
European journal of medicinal chemistry 2024 Jan 15;264:116039
European journal of medicinal chemistry 2024 Jan 15;264:116039
Preliminary study on the role of the CSMD2 gene in bladder cancer.
Yao Z, Yang H, Liu X, Jiang M, Deng W, Fu B
Heliyon 2024 Jan 15;10(1):e22593
Heliyon 2024 Jan 15;10(1):e22593
GDF11 mediates H(2)S to prevent chronic stress-induced cognitive impairment by reducing hippocampal NLRP3/caspase-1-dependent pyroptosis.
Wang B, Chen SM, Yang SQ, Jiang JM, Zhang P, Zou W, Tang XQ
Journal of affective disorders 2024 Jan 1;344:600-611
Journal of affective disorders 2024 Jan 1;344:600-611
Mechanism of synergistic inhibitory effect of benzyl isothiocyanate and zoledronic acid combination on breast cancer induction of osteoclast differentiation.
Hahm ER, Kim SH, Pore SK, Mathan SV, Singh RP, Singh SV
Molecular carcinogenesis 2024 Feb;63(2):301-313
Molecular carcinogenesis 2024 Feb;63(2):301-313
Aucubin provides protection against cerebral ischaemia-reperfusion injury by suppressing neuronal apoptosis, oxidative stress, and inflammation through the modulation of the AKT-GSK-3β-Nrf2 signal cascade.
Yang F, Lian Q, Zhang X, Sun F, Jia S, Zhao W
Toxicology and applied pharmacology 2024 Feb;483:116829
Toxicology and applied pharmacology 2024 Feb;483:116829
Circular RNA RHBDD1 regulates tumorigenicity and ferroptosis in colorectal cancer by mediating the ELAVL1/SCD mRNA interaction.
Long F, Zhong C, Long Q, Zhu K, Wang J, Yu Y, Xie C, Hu G
Cancer gene therapy 2024 Feb;31(2):237-249
Cancer gene therapy 2024 Feb;31(2):237-249
Single-cell multi-omics profiling of human preimplantation embryos identifies cytoskeletal defects during embryonic arrest.
Wang T, Peng J, Fan J, Tang N, Hua R, Zhou X, Wang Z, Wang L, Bai Y, Quan X, Wang Z, Zhang L, Luo C, Zhang W, Kang X, Liu J, Li L, Li L
Nature cell biology 2024 Feb;26(2):263-277
Nature cell biology 2024 Feb;26(2):263-277
CDC123 promotes Hepatocellular Carcinoma malignant progression by regulating CDKAL1.
Wang Y, Pan H, Gong X, Wang Z, Qin X, Zhou S, Zhu C, Hu X, Chen S, Liu H, Jin H, Pang Q, Wu W
Pathology, research and practice 2024 Feb;254:154987
Pathology, research and practice 2024 Feb;254:154987
A prognostic model based on Scissor(+) cancer associated fibroblasts identified from bulk and single cell RNA sequencing data in head and neck squamous cell carcinoma.
Tian G, Zhang J, Bao Y, Li Q, Hou J
Cellular signalling 2024 Feb;114:110984
Cellular signalling 2024 Feb;114:110984
Discovery of PRDM16-Mediated TRPA1 Induction as the Mechanism for Low Tubulo-Interstitial Fibrosis in Diabetic Kidney Disease.
Xu F, Jiang H, Li X, Pan J, Li H, Wang L, Zhang P, Chen J, Qiu S, Xie Y, Li Y, Zhang D, Dong Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2306704
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2306704
CEBPA Overexpression Enhances β-Cell Proliferation and Survival.
Ellsworth PN, Herring JA, Leifer AH, Ray JD, Elison WS, Poulson PD, Crabtree JE, Van Ry PM, Tessem JS
Biology 2024 Feb 9;13(2)
Biology 2024 Feb 9;13(2)
Warm Acupuncture Reduces Pain and Inflammation in Rats with Lumbar Disc Herniation Induced by Autologous Nucleus Pulposus Transplantation via Regulating p38MAPK/NF-κB Pathway.
Pan F, Zeng F, Chen Y, Zheng Y, Chen Z, Zhu X, Yin MF, Huang Y, Liu Z
Journal of acupuncture and meridian studies 2024 Feb 29;17(1):28-37
Journal of acupuncture and meridian studies 2024 Feb 29;17(1):28-37
Identification of hypoxia- and immune-related biomarkers in patients with ischemic stroke.
Zhang H, Sun J, Zou P, Huang Y, Yang Q, Zhang Z, Luo P, Jiang X
Heliyon 2024 Feb 29;10(4):e25866
Heliyon 2024 Feb 29;10(4):e25866
Specific inhibition of TET1 in the spinal dorsal horn alleviates inflammatory pain in mice by regulating synaptic plasticity.
Yang K, Wei R, Liu Q, Tao Y, Wu Z, Yang L, Wang QH, Wang H, Pan Z
Neuropharmacology 2024 Feb 15;244:109799
Neuropharmacology 2024 Feb 15;244:109799
Electroacupuncture stimulation ameliorates cognitive impairment induced by long-term high-fat diet by regulating microglial BDNF.
Yang X, Yu Z, An L, Jing X, Yuan M, Xu T, Yu Z, Xu B, Lu M
Brain research 2024 Feb 15;1825:148710
Brain research 2024 Feb 15;1825:148710
MiR-145-5p overexpression rejuvenates aged adipose stem cells and accelerates wound healing.
Li C, Ren S, Xiong H, Chen J, Jiang T, Guo J, Yan C, Chen Z, Yang X, Xu X
Biology open 2024 Feb 15;13(2)
Biology open 2024 Feb 15;13(2)
Calcitonin gene-related peptide attenuated discogenic low back pain in rats possibly via inhibiting microglia activation.
Xie W, Li F, Han Y, Chi X, Qin Y, Ye F, Li Z, Xiao J
Heliyon 2024 Feb 15;10(3):e25906
Heliyon 2024 Feb 15;10(3):e25906
Tanshinone IIA alleviates inflammation-induced skeletal muscle atrophy by regulating mitochondrial dysfunction.
Han D, Chen YB, Zhao K, Li HZ, Chen XY, Zhu GZ, Tu C, Gao JW, Zhuang JS, Wu ZY, Zhong ZM
Archives of biochemistry and biophysics 2024 Dec;762:110215
Archives of biochemistry and biophysics 2024 Dec;762:110215
M2 macrophages promote subconjunctival fibrosis through YAP/TAZ signalling.
Wang Y, Geng X, Guo Z, Chu D, Liu R, Cheng B, Cui H, Li C, Li J, Li Z
Annals of medicine 2024 Dec;56(1):2313680
Annals of medicine 2024 Dec;56(1):2313680
Tumour cell-released autophagosomes promote lung metastasis by upregulating PD-L1 expression in pulmonary vascular endothelial cells in breast cancer.
Wang XR, Zhou XH, Sun XT, Shen YQ, Wu YY, Wu CD, Zhu FJ, Wei YT, Chen JP, Chen J, Zheng SY, Wang LX
Cellular oncology (Dordrecht, Netherlands) 2024 Dec;47(6):2147-2162
Cellular oncology (Dordrecht, Netherlands) 2024 Dec;47(6):2147-2162
Attenuation of high-fat diet-induced weight gain by apolipoprotein A4.
Kuo HN, LaRussa Z, Xu FM, Consitt LA, Liu M, Davidson WS, Puri V, Coschigano KT, Shi H, Lo CC
Obesity (Silver Spring, Md.) 2024 Dec;32(12):2321-2333
Obesity (Silver Spring, Md.) 2024 Dec;32(12):2321-2333
Foxk1 promotes bone formation through inducing aerobic glycolysis.
Liu C, Feng N, Wang Z, Zheng K, Xie Y, Wang H, Long H, Peng S
Cell death and differentiation 2024 Dec;31(12):1650-1663
Cell death and differentiation 2024 Dec;31(12):1650-1663
Sorafenib and SIAIS361034, a novel PROTAC degrader of BCL-x(L), display synergistic antitumor effects on hepatocellular carcinoma with minimal hepatotoxicity.
Zhang X, Tao Y, Xu Z, Jiang B, Yang X, Huang T, Tan W
Biochemical pharmacology 2024 Dec;230(Pt 1):116542
Biochemical pharmacology 2024 Dec;230(Pt 1):116542
Sulforaphane acts through the NFE2L2/AMPK signaling pathway to protect boar spermatozoa from cryoinjury by activating antioxidant defenses.
Zhang G, Wen F, Li Y, Sun P, Li Y, Hu Z, Wang H, Ma Y, Liang G, Chen L, Yang K, Hu J
Theriogenology 2024 Dec;230:330-340
Theriogenology 2024 Dec;230:330-340
Hymenolepis nana antigens alleviate ulcerative colitis by promoting intestinal stem cell proliferation and differentiation via AhR/IL-22 signaling pathway.
Cui X, Cheng Y, Wang H, Li X, Li J, Zhang K, Mou R
PLoS neglected tropical diseases 2024 Dec;18(12):e0012714
PLoS neglected tropical diseases 2024 Dec;18(12):e0012714
Nervous necrosis virus induced vacuolization is a Rab5- and actin-dependent process.
Liu J, Wang L, Zhang X, Wang S, Qin Q
Virulence 2024 Dec;15(1):2301244
Virulence 2024 Dec;15(1):2301244
Gastrodia elata specific miRNA attenuates neuroinflammation via modulating NF-κB signaling pathway.
Fu J, Lu ZT, Wu G, Yang ZC, Wu X, Wang D, Nie ZM, Sheng Q
The International journal of neuroscience 2024 Dec;134(12):1652-1662
The International journal of neuroscience 2024 Dec;134(12):1652-1662
OTUD1 regulates cytokine expression and related pathways in goose fatty liver by promoting deubiquitination of its target proteins.
Zhou X, Xing Y, Wang Y, Lv M, Zhang P, Zhu S, Ge J, Liu L, Zhao M, Gong H, Gong D, Geng T
Poultry science 2024 Dec;103(12):104382
Poultry science 2024 Dec;103(12):104382
α-linolenic acid mitigates microglia-mediated neuroinflammation of schizophrenia in mice by suppressing the NF-κB/NLRP3 pathway via binding GPR120-β-arrestin 2.
Wang T, Liu S, Shen W, Liu J, Liu Y, Li Y, Zhang F, Li T, Zhang X, Tian W, Zhang J, Ma J, Guo Y, Mi X, Lin Y, Hu Q, Zhang X, Liu J, Wang H
International immunopharmacology 2024 Dec 5;142(Pt A):113047
International immunopharmacology 2024 Dec 5;142(Pt A):113047
The Mitochondrial Fusion Promoter M1 Mitigates Cigarette Smoke-Induced Airway Inflammation and Oxidative Stress via the PI3K-AKT Signaling Pathway.
Zeng T, Liu L, Xu D, Wang T, Wu Y, Qin J, Gao L, Chen M, Li X, Li D, Chen J, Shen Y, Wen F
Lung 2024 Dec 3;203(1):12
Lung 2024 Dec 3;203(1):12
Isoliquiritigenin alleviates neuropathic pain by reducing microglia inflammation through inhibition of the ERK signaling pathway and decreasing CEBPB transcription expression.
Wang Z, Jia S, Kang X, Chen S, Zhang L, Tian Z, Liang X, Meng C
International immunopharmacology 2024 Dec 25;143(Pt 3):113536
International immunopharmacology 2024 Dec 25;143(Pt 3):113536
Colorectal cancer cells establish metabolic reprogramming with cancer-associated fibroblasts (CAFs) through lactate shuttle to enhance invasion, migration, and angiogenesis.
Wang X, Qu Y, Ji J, Liu H, Luo H, Li J, Han X
International immunopharmacology 2024 Dec 25;143(Pt 2):113470
International immunopharmacology 2024 Dec 25;143(Pt 2):113470
Desuccinylation of TBK1 by SIRT5 regulates inflammatory response of macrophages in sepsis.
Zhang X, Ling C, Xiong Z, Gong T, Luo S, Liu X, Zhang L, Liao C, Lu Y, Huang X, Zhou W, Zhou S, Liu Y, Tang J
Cell reports 2024 Dec 24;43(12):115060
Cell reports 2024 Dec 24;43(12):115060
Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma.
Wang H, Yi X, Wang X, Yang Y, Zhang H, Wang H, Chen J, Zhang B, Guo S, Wu L, Du J, Chen Y, Sun N, Gao T, Zhang R, Bian H, Jia L, Li C, Guo W
Cell reports 2024 Dec 24;43(12):115015
Cell reports 2024 Dec 24;43(12):115015
OSGEP regulates islet β-cell function by modulating proinsulin translation and maintaining ER stress homeostasis in mice.
Liu Y, Yang X, Zhou J, Yang H, Yang R, Zhu P, Zhou R, Wu T, Gao Y, Ye Z, Li X, Liu R, Zhang W, Zhou H, Li Q
Nature communications 2024 Dec 2;15(1):10479
Nature communications 2024 Dec 2;15(1):10479
Fish Snx27 promotes viral products by modulating the innate immune response and exosomal machinery.
Yu Y, Liu J, Zhao Z, Lan X, Li L, Hu J, Zang Y-a, Zhang X, Chen J
Journal of virology 2024 Dec 17;98(12):e0097424
Journal of virology 2024 Dec 17;98(12):e0097424
Comparison of Endoplasmic Reticulum Stress and Pyroptosis Induced by Pathogenic Calcium Oxalate Monohydrate and Physiologic Calcium Oxalate Dihydrate Crystals in HK-2 Cells: Insights into Kidney Stone Formation.
Nong WJ, Tong XY, Ouyang JM
Cells 2024 Dec 15;13(24)
Cells 2024 Dec 15;13(24)
Cannabidiol Suppresses Metastatic Castration-Resistant Prostate Cancer Progression and Recurrence through Modulating Tryptophan Catabolism.
Mudhish EA, Ebrahim HY, Helal IE, Alhowiriny AT, El Sayed KA
ACS pharmacology & translational science 2024 Dec 13;7(12):3902-3913
ACS pharmacology & translational science 2024 Dec 13;7(12):3902-3913
Pharmacological Inhibition of Astrocytic Transglutaminase 2 Facilitates the Expression of a Neurosupportive Astrocyte Reactive Phenotype in Association with Increased Histone Acetylation.
Delgado T, Emerson J, Hong M, Keillor JW, Johnson GVW
Biomolecules 2024 Dec 13;14(12)
Biomolecules 2024 Dec 13;14(12)
The essential role of TTC28 in maintaining chromosomal stability via HSPA8 chaperone-mediated autophagy.
Zhang G, Xiang M, Gu L, Zhou J, Zhang B, Tian W, Deng D
Proceedings of the National Academy of Sciences of the United States of America 2024 Dec 10;121(50):e2409447121
Proceedings of the National Academy of Sciences of the United States of America 2024 Dec 10;121(50):e2409447121
Hyaluronic acid-modified extracellular vesicles for targeted doxorubicin delivery in hepatocellular carcinoma.
Liu Y, Hinnant B, Chen S, Tao H, Huang Z, Qian M, Zhou M, Han Z, Han ZC, Zhang J, Li Z
Experimental cell research 2024 Dec 1;443(2):114332
Experimental cell research 2024 Dec 1;443(2):114332
Baicalein suppresses Coxsackievirus B3 replication by inhibiting caspase-1 and viral protease 2A.
Dong Y, Shao E, Li S, Wang R, Wang D, Wang L, Yang H, He Y, Luan T, Chen Y, Wang Y, Lin L, Wang Y, Zhong Z, Zhao W
Virologica Sinica 2024 Aug;39(4):685-693
Virologica Sinica 2024 Aug;39(4):685-693
Hunnivirus structural protein VP2 inhibits beta interferon production by targeting the IRF3 essential modulator.
Zhu X, Dong Q, Zhang K, Zou Y, Zhang G, Du Y, Mo X, Wu A, Ouyang K, Chen Y, Wei Z, Qin Y, Pan Y, Huang W
Veterinary microbiology 2024 Aug;295:110148
Veterinary microbiology 2024 Aug;295:110148
Permethrin exposure impacts zebrafish lipid metabolism via the KRAS-PPAR-GLUT signaling pathway, which is mediated by oxidative stress.
Khan A, Khan B, Hussain S, Wang Y, Mai W, Hou Y
Aquatic toxicology (Amsterdam, Netherlands) 2024 Aug;273:107021
Aquatic toxicology (Amsterdam, Netherlands) 2024 Aug;273:107021
Celastrol alleviates subconjunctival fibrosis induced by silicone implants mimicking glaucoma surgery.
Wang Y, Geng X, Sun X, Cui H, Guo Z, Chu D, Li J, Li Z
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2024 Aug;201:114352
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2024 Aug;201:114352
A ROS-responsive and scavenging hydrogel for postoperative abdominal adhesion prevention.
Zhang T, Huang Y, Gong Y, Shi X, Xiao D, Ren L, Dai X, Zeng Z, Zhao C
Acta biomaterialia 2024 Aug;184:98-113
Acta biomaterialia 2024 Aug;184:98-113
Carnosic Acid: A Novel Selective Inhibitor of ERAP1 by Direct Binding and Its Modulation of Antigen Processing and Presentation.
Wu J, Li Z, Liu X, Feng D, Liang R, Su X, Li D, Hua H, Cao H
Journal of agricultural and food chemistry 2024 Aug 7;72(31):17343-17355
Journal of agricultural and food chemistry 2024 Aug 7;72(31):17343-17355
Exome-wide association study identifies KDELR3 mutations in extreme myopia.
Yuan J, Zhuang YY, Liu X, Zhang Y, Li K, Chen ZJ, Li D, Chen H, Liang J, Yao Y, Yu X, Zhuo R, Zhao F, Zhou X, Myopia Associated Genetics and Intervention Consortium, Yu X, Qu J, Su J
Nature communications 2024 Aug 7;15(1):6703
Nature communications 2024 Aug 7;15(1):6703
Micro-Infusion of 5-HT1a Receptor Antagonists into the Ventral Subiculum Ameliorate MK-801 Induced Schizophrenia-Like Behavior in Rats.
Zhang M, Qian X, Wei Z, Chen K, Ding H, Jia J, Li Y, Liu S, Yang K, Wang J, Chen H, Zhang W
Neuroscience 2024 Aug 6;552:115-125
Neuroscience 2024 Aug 6;552:115-125
PERK inhibitor (ISRIB) improves depression-like behavior by inhibitions of HPA-axis over-activation in mice exposed to chronic restraint stress.
Luhong L, Zhou HM, Tang XH, Chen J, Zhang AM, Zhou CL, Li SY, Wen Yu C, Liyan H, Xiang YY, Yang X
Behavioural brain research 2024 Aug 5;471:115122
Behavioural brain research 2024 Aug 5;471:115122
Cystathionine Gamma-Lyase Regulates TNF-α-Mediated Injury Response in Human Colonic Epithelial Cells and Colonoids.
Arroyo Almenas F, Törő G, Szaniszlo P, Maskey M, Thanki KK, Koltun WA, Yochum GS, Pinchuk IV, Chao C, Hellmich MR, Módis K
Antioxidants (Basel, Switzerland) 2024 Aug 31;13(9)
Antioxidants (Basel, Switzerland) 2024 Aug 31;13(9)
The role of chromatin modulator DPY30 in glucose metabolism of colorectal cancer cells.
Mao X, Yang S, Zhang Y, Yang H, Yan D, Zhang L
Translational cancer research 2024 Aug 31;13(8):4205-4218
Translational cancer research 2024 Aug 31;13(8):4205-4218
Lactate promotes microglial scar formation and facilitates locomotor function recovery by enhancing histone H4 lysine 12 lactylation after spinal cord injury.
Hu X, Huang J, Li Z, Li J, Ouyang F, Chen Z, Li Y, Zhao Y, Wang J, Yu S, Jing J, Cheng L
Journal of neuroinflammation 2024 Aug 3;21(1):193
Journal of neuroinflammation 2024 Aug 3;21(1):193
OTU deubiquitinase, ubiquitin aldehyde binding 2 (OTUB2) modulates the stemness feature, chemoresistance, and epithelial-mesenchymal transition of colon cancer via regulating GINS complex subunit 1 (GINS1) expression.
Zhu W, Wu C, Liu Z, Zhao S, Huang J
Cell communication and signaling : CCS 2024 Aug 29;22(1):420
Cell communication and signaling : CCS 2024 Aug 29;22(1):420
A pro-metastatic tRNA fragment drives aldolase A oligomerization to enhance aerobic glycolysis in lung adenocarcinoma.
Wang Q, Song X, Zhang Y, Liang S, Zhang M, Wang H, Feng Y, Li R, Ding H, Chen Y, Xia W, Dong G, Xu L, Mao Q, Jiang F
Cell reports 2024 Aug 27;43(8):114550
Cell reports 2024 Aug 27;43(8):114550
Effect of X-ray irradiation on renal excretion of bestatin through down-regulating organic anion transporters via the vitamin D receptor in rats.
Dong S, Yang F, Zhang Y, Teng Y, Tang W, Liu J, Fan H
Chemico-biological interactions 2024 Aug 25;399:111123
Chemico-biological interactions 2024 Aug 25;399:111123
Electroacupuncture negatively regulates the Nesfatin-1/ERK/CREB pathway to alleviate HPA axis hyperactivity and anxiety-like behaviors caused by surgical trauma.
Zheng J, Wang Y, Zhang C, Zhang A, Zhou Y, Xu Y, Yu J, Tian Z
Chinese medicine 2024 Aug 17;19(1):108
Chinese medicine 2024 Aug 17;19(1):108
Integrating bulk and single-cell sequencing reveals metastasis-associated CAFs in head and neck squamous cell carcinoma.
Yao Y, Tian G, Zhang J, Zhang S, Liu X, Hou J
Life sciences 2024 Aug 15;351:122768
Life sciences 2024 Aug 15;351:122768
Acetylation-dependent deubiquitinase USP26 stabilizes BAG3 to promote breast cancer progression.
Liu J, Zhai M, Chen Y, Wei Y, Li F, Chen Y, Duan B, Xing L, Du H, Jiang M, Li H, Ren G
Cancer letters 2024 Aug 10;597:217005
Cancer letters 2024 Aug 10;597:217005
FGF2 promotes the proliferation of injured granulosa cells in premature ovarian failure via Hippo-YAP signaling pathway.
Cheng F, Wang J, Wang R, Pan R, Cui Z, Wang L, Wang L, Yang X
Molecular and cellular endocrinology 2024 Aug 1;589:112248
Molecular and cellular endocrinology 2024 Aug 1;589:112248
Silencing lncRNA-DARS-AS1 suppresses nonsmall cell lung cancer progression by stimulating miR-302a-3p to inhibit ACAT1 expression.
Li J, Li Y, Sun X, Wei L, Guan J, Fu L, Du J, Zhang X, Cheng M, Ma H, Jiang S, Zheng Q, Wang L
Molecular carcinogenesis 2024 Apr;63(4):757-771
Molecular carcinogenesis 2024 Apr;63(4):757-771
CRISPR/Cas9 based gene editing of Frizzled class receptor 6 (FZD6) reveals its role in depressive symptoms through disrupting Wnt/β-catenin signaling pathway.
Han H, Xu M, Wang J, Li MD, Yang Z
Journal of advanced research 2024 Apr;58:129-138
Journal of advanced research 2024 Apr;58:129-138
Mechanism of acupuncture in attenuating cerebral ischaemia-reperfusion injury based on nuclear receptor coactivator 4 mediated ferritinophagy.
Xinchang Z, Zheng H, Peiyan H, Mengning Y, Zhihui Z, Guangxia NI
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Apr;44(2):345-352
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2024 Apr;44(2):345-352
Icariin alleviates renal inflammation and tubulointerstitial fibrosis via Nrf2-mediated attenuation of mitochondrial damage.
Ding N, Sun S, Zhou S, Lv Z, Wang R
Cell biochemistry and function 2024 Apr;42(3):e4005
Cell biochemistry and function 2024 Apr;42(3):e4005
Citric acid promotes SPARC release in pancreatic cancer cells and inhibits the progression of pancreatic tumors in mice on a high-fat diet.
Xiao G, Wei Y, Xie R, Tsang Y, Gu J, Shen D, Ding M, Yuan J, Xu D, Fei J
The FEBS journal 2024 Apr;291(8):1699-1718
The FEBS journal 2024 Apr;291(8):1699-1718
A novel and ubiquitous miRNA-involved regulatory module ensures precise phosphorylation of RNA polymerase II and proper transcription.
Wang Z, Zhong S, Zhang S, Zhang B, Zheng Y, Sun Y, Zhang Q, Liu X
PLoS pathogens 2024 Apr;20(4):e1012138
PLoS pathogens 2024 Apr;20(4):e1012138
Clock knockout in inhibitory neurons reduces predisposition to epilepsy and influences anxiety-like behaviors in mice.
Deng L, Jiang H, Lin J, Xu D, Qi A, Guo Q, Li PP, Wang X, Liu JS, Fu X, Li P
Neurobiology of disease 2024 Apr;193:106457
Neurobiology of disease 2024 Apr;193:106457
Human amniotic mesenchymal stromal cell-derived exosomes promote neuronal function by inhibiting excessive apoptosis in a hypoxia/ischemia-induced cerebral palsy model: A preclinical study.
Zhou Y, He LN, Wang LN, Chen KY, Qian SD, Li XH, Zang J, Wang DM, Yu XF, Gao J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116321
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Apr;173:116321
HSPA4 upregulation induces immune evasion via ALKBH5/CD58 axis in gastric cancer.
Suo D, Gao X, Chen Q, Zeng T, Zhan J, Li G, Zheng Y, Zhu S, Yun J, Guan XY, Li Y
Journal of experimental & clinical cancer research : CR 2024 Apr 8;43(1):106
Journal of experimental & clinical cancer research : CR 2024 Apr 8;43(1):106
Short-term regulation of TSFM level does not alter amyloidogenesis and mitochondrial function in type-specific cells.
Li XY, Zhou GF, Xie XY, Pu YL, -Chen X, Li CL, Yang J, Wang L, Chen GJ
Molecular biology reports 2024 Apr 5;51(1):484
Molecular biology reports 2024 Apr 5;51(1):484
Evolutionary genetics of pulmonary anatomical adaptations in deep-diving cetaceans.
Guo B, Sun Y, Wang Y, Zhang Y, Zheng Y, Xu S, Yang G, Ren W
BMC genomics 2024 Apr 4;25(1):339
BMC genomics 2024 Apr 4;25(1):339
Identification of ferroptosis related genes and pathways in prostate cancer cells under erastin exposure.
Wu F, Huang F, Jiang N, Su J, Yao S, Liang B, Li W, Yan T, Zhou S, Zhou Q
BMC urology 2024 Apr 4;24(1):78
BMC urology 2024 Apr 4;24(1):78
Static magnetic field-induced IL-6 secretion in periodontal ligament stem cells accelerates orthodontic tooth movement.
Luo S, Li Z, Liu L, Zhao J, Ge W, Zhang K, Zhou Z, Liu Y
Scientific reports 2024 Apr 29;14(1):9851
Scientific reports 2024 Apr 29;14(1):9851
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression.
Wu J, Wen T, Marzio A, Song D, Chen S, Yang C, Zhao F, Zhang B, Zhao G, Ferri A, Cheng H, Ma J, Ren H, Chen QY, Yang Y, Qin S
Cell death & disease 2024 Apr 20;15(4):282
Cell death & disease 2024 Apr 20;15(4):282
The role of FPR2-mediated ferroptosis in formyl peptide-induced acute lung injury against endothelial barrier damage and protective effect of the mitochondria-derived peptide MOTS-c.
Wen Z, Fan J, Zhan F, Li X, Li B, Lu P, Yao X, Shen Z, Liu Z, Wang C, Li X, Jin W, Zhang X, Qi Y, Wang X, Song M
International immunopharmacology 2024 Apr 20;131:111911
International immunopharmacology 2024 Apr 20;131:111911
PEI, a new transfection method, augments the inhibitory effect of RBM5 on prostate cancer.
Zhou X, Cao Y, Li R, Di X, Wang Y, Wang K
Biochemical and biophysical research communications 2024 Apr 16;704:149703
Biochemical and biophysical research communications 2024 Apr 16;704:149703
Phosphoglycerate mutase 5 exacerbates liver ischemia-reperfusion injury by activating mitochondrial fission.
Tang H, Yu Q, Chen X, Zhang J, Guo D, Guo W, Zhang S, Shi X
Scientific reports 2024 Apr 12;14(1):8535
Scientific reports 2024 Apr 12;14(1):8535
Germline USP36 Mutation Confers Resistance to EGFR-TKIs by Upregulating MLLT3 Expression in Patients with Non-Small Cell Lung Cancer.
Guan S, Chen X, Wei Y, Wang F, Xie W, Chen Y, Liang H, Zhu X, Yang Y, Fang W, Huang Y, Zhao H, Zhang X, Liu S, Zhuang W, Huang M, Wang X, Zhang L
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Apr 1;30(7):1382-1396
Clinical cancer research : an official journal of the American Association for Cancer Research 2024 Apr 1;30(7):1382-1396
Circulating THBS1: A Risk Factor for Nonalcoholic Fatty Liver Disease in Obese Children.
Li M, Liu L, Kang Y, Huang S, Xiao Y
Annals of nutrition & metabolism 2023;79(1):16-28
Annals of nutrition & metabolism 2023;79(1):16-28
Absent in melanoma 2 attenuates proliferation and migration and promotes apoptosis of human colorectal cancer cells by activating P38MAPK signaling pathway.
Zhang Z, Li X, Zhang Y, Zhu H, Qiao Z, Lu Y, Mi X, Cao H, Shen G, He S
Oncology research 2023;32(2):353-360
Oncology research 2023;32(2):353-360
Penfluroidol Attenuates the Imbalance of the Inflammatory Response by Repressing the Activation of the NLRP3 Inflammasome and Reduces Oxidative Stress via the Nrf2/HO-1 Signaling Pathway in LPS-Induced Macrophages.
Li Q, Wu L, Cheng B, Tao S, Wang W, Luo Z, Fan J
Mediators of inflammation 2023;2023:9940858
Mediators of inflammation 2023;2023:9940858
S100 Calcium Binding Protein A16 Promotes Cell Proliferation by triggering LATS1 ubiquitin degradation mediated by CUL4A ligase to inhibit Hippo pathway in Glioma development.
Hu Y, Zhang R, Lu S, Zhang W, Wang D, Ge Y, Jiang F, Qin X, Liu Y
International journal of biological sciences 2023;19(7):2034-2052
International journal of biological sciences 2023;19(7):2034-2052
XPOT Disruption Suppresses TNBC Growth through Inhibition of Specific tRNA Nuclear Exportation and TTC19 Expression to Induce Cytokinesis Failure.
Dai H, Yang X, Sheng X, Wang Y, Zhang S, Zhang X, Hu L, Zhang Z, Dong X, Yin W, Yao L, Lu J
International journal of biological sciences 2023;19(16):5319-5336
International journal of biological sciences 2023;19(16):5319-5336
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
Zhu Y, Sun W, Jiang X, Bai R, Luo Y, Gao Y, Li S, Huang Z, Gong Y, Xie C
PloS one 2023;18(1):e0281132
PloS one 2023;18(1):e0281132
Sodium Butyrate Ameliorates Type 2 Diabetes-Related Sarcopenia Through IL-33-Independent ILC2s/IL-13/STAT3 Signaling Pathway.
Cao Y, Li Y, Han W, Jia X, Zhu P, Wei B, Cong X, Wang Z
Journal of inflammation research 2023;16:343-358
Journal of inflammation research 2023;16:343-358
Electroacupuncture alleviates perioperative hypothalamus-pituitary-adrenal axis dysfunction via circRNA-miRNA-mRNA networks.
Wang Y, Hu W, Han J, Zheng J, Jiang N, Feng Y, Tian Z
Frontiers in molecular neuroscience 2023;16:1115569
Frontiers in molecular neuroscience 2023;16:1115569
Prognostic values of Annexins and validation of the influence on cell proliferation, migration, and invasion in uveal melanoma.
Zhao A, Wang Z, Wang Y, Chen X
American journal of translational research 2023;15(5):3131-3151
American journal of translational research 2023;15(5):3131-3151
HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication.
Yuan S, Xu J, Wang M, Huang J, Ma S, Liu Y, Ke Y, Zeng X, Wu K, Wang J, Tian X, Zheng D, Yousaf T, Naz W, Sun J, Chen L, Guo D, Guo M, Sun G
Cellular and molecular gastroenterology and hepatology 2023;15(1):179-195
Cellular and molecular gastroenterology and hepatology 2023;15(1):179-195
Neutrophil infiltration associated genes on the prognosis and tumor immune microenvironment of lung adenocarcinoma.
Liu R, Zhu G, Sun Y, Li M, Hu Z, Cao P, Li X, Song Z, Chen J
Frontiers in immunology 2023;14:1304529
Frontiers in immunology 2023;14:1304529
Porcine epidemic diarrhea virus causes diarrhea by activating EGFR to regulates NHE3 activity and mobility on plasma membrane.
Zhang Y, Zhang S, Sun Z, Liu X, Liao G, Niu Z, Kan Z, Xu S, Zhang J, Zou H, Zhang X, Song Z
Frontiers in microbiology 2023;14:1237913
Frontiers in microbiology 2023;14:1237913
Weight bearing training alleviates muscle atrophy and pyroptosis of middle-aged rats.
Fu P, Gong L, Yang L, Tang S, Ma F
Frontiers in endocrinology 2023;14:1202686
Frontiers in endocrinology 2023;14:1202686
The overexpression of actin related protein 2/3 complex subunit 1B(ARPC1B) promotes the ovarian cancer progression via activation of the Wnt/β-catenin signaling pathway.
Huang J, Zhou H, Tan C, Mo S, Liu T, Kuang Y
Frontiers in immunology 2023;14:1182677
Frontiers in immunology 2023;14:1182677
Selenomethionine against titanium particle-induced osteolysis by regulating the ROS-dependent NLRP3 inflammasome activation via the β-catenin signaling pathway.
Yu R, Yuan Y, Liu Z, Liu L, Xu Z, Zhao Y, Jia C, Zhang P, Li H, Liu Y, Wang Y, Li W, Nie L, Sun X, Li Y, Liu B, Liu H
Frontiers in immunology 2023;14:1171150
Frontiers in immunology 2023;14:1171150
Pan-cancer analysis of Krüppel-like factor 3 and its carcinogenesis in pancreatic cancer.
Zhu J, Teng H, Zhu X, Yuan J, Zhang Q, Zou Y
Frontiers in immunology 2023;14:1167018
Frontiers in immunology 2023;14:1167018
Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis via the p38/p53/p21 pathway.
Xiong D, Gao F, Shao J, Pan Y, Wang S, Wei D, Ye S, Chen Y, Chen R, Yue B, Li J, Chen J
Frontiers in pharmacology 2023;14:1141800
Frontiers in pharmacology 2023;14:1141800
Application of a JEG-3 organoid model to study HLA-G function in the trophoblast.
Zhuang BM, Cao DD, Liu XF, Wang L, Lin XL, Duan YG, Lee CL, Chiu PCN, Yeung WSB, Yao YQ
Frontiers in immunology 2023;14:1130308
Frontiers in immunology 2023;14:1130308
Grouper cGAS is a negative regulator of STING-mediated interferon response.
Zhang L, Zhang X, Liao J, Xu L, Kang S, Chen H, Sun M, Wu S, Xu Z, Wei S, Qin Q, Wei J
Frontiers in immunology 2023;14:1092824
Frontiers in immunology 2023;14:1092824
Tsp-1(+) microglia attenuate retinal neovascularization by maintaining the expression of Smad3 in endothelial cells through exosomes with decreased miR-27a-5p.
Luo Q, Jiang Z, Jiang J, Wan L, Li Y, Huang Y, Qiu J, Yu K, Zhuang J
Theranostics 2023;13(11):3689-3706
Theranostics 2023;13(11):3689-3706
Targeting plasmodium α-tubulin-1 to block malaria transmission to mosquitoes.
Zhang G, Niu G, Hooker-Romera D, Shabani S, Ramelow J, Wang X, Butler NS, James AA, Li J
Frontiers in cellular and infection microbiology 2023;13:1132647
Frontiers in cellular and infection microbiology 2023;13:1132647
Inhibition of Hypothalamic FTO Activates STAT3 Signal through ERK1/2 Associated with Reductions in Food Intake and Body Weight.
Hu F, Yan HJ, Gao CX, Sun WW, Long YS
Neuroendocrinology 2023;113(1):80-91
Neuroendocrinology 2023;113(1):80-91
Combined effects of EMP and RF field on emotional behavior in mice.
Qin T, Liu L, Wang X, Guo L, Lin J, Du J, Xue Y, Lai P, Jing Y, Ding G
Frontiers in public health 2023;11:1087161
Frontiers in public health 2023;11:1087161
The protective role of EP300 in monocrotaline-induced pulmonary hypertension.
Yang L, Tian J, Wang J, Zeng J, Wang T, Lin B, Linneman J, Li L, Niu Y, Gou D, Zhang Y
Frontiers in cardiovascular medicine 2023;10:1037217
Frontiers in cardiovascular medicine 2023;10:1037217
Effect of renal denervation on cardiac remodelling and function in rats with chronic intermittent hypoxia.
Lu D, Wang K, Jiang W, Zhang H, Zhang H
Clinical and experimental pharmacology & physiology 2023 Sep;50(9):719-727
Clinical and experimental pharmacology & physiology 2023 Sep;50(9):719-727
Aβ Induces Neuroinflammation and Microglial M1 Polarization via cGAS-STING-IFITM3 Signaling Pathway in BV-2 Cells.
Wu Z, Tang W, Ibrahim FEEM, Chen X, Yan H, Tao C, Wang Z, Guo Y, Fu Y, Wang Q, Ge Y
Neurochemical research 2023 Sep;48(9):2881-2894
Neurochemical research 2023 Sep;48(9):2881-2894
DELE1 oligomerization promotes integrated stress response activation.
Yang J, Baron KR, Pride DE, Schneemann A, Guo X, Chen W, Song AS, Aviles G, Kampmann M, Wiseman RL, Lander GC
Nature structural & molecular biology 2023 Sep;30(9):1295-1302
Nature structural & molecular biology 2023 Sep;30(9):1295-1302
STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1(+) NK cells.
Lu L, Yang C, Zhou X, Wu L, Hong X, Li W, Wang X, Yang Y, Cao D, Zhang A, Di W, Deng L
Cell reports 2023 Sep 26;42(9):113108
Cell reports 2023 Sep 26;42(9):113108
Optineurin tunes outside-in signaling to regulate lysosome biogenesis and phagocytic clearance in the retina.
Tan LX, Germer CJ, Thamban T, La Cunza N, Lakkaraju A
Current biology : CB 2023 Sep 25;33(18):3805-3820.e7
Current biology : CB 2023 Sep 25;33(18):3805-3820.e7
Steroidal saponins PPI/CCRIS/PSV induce cell death in pancreatic cancer cell through GSDME-dependent pyroptosis.
Liu Y, Zhang W, Zhou H, Chen J
Biochemical and biophysical research communications 2023 Sep 17;673:51-58
Biochemical and biophysical research communications 2023 Sep 17;673:51-58
MicroRNA miR-223 modulates NLRP3 and Keap1, mitigating lipopolysaccharide-induced inflammation and oxidative stress in bovine mammary epithelial cells and murine mammary glands.
Zhou M, Barkema HW, Gao J, Yang J, Wang Y, Kastelic JP, Khan S, Liu G, Han B
Veterinary research 2023 Sep 14;54(1):78
Veterinary research 2023 Sep 14;54(1):78
EP300 promotes ferroptosis via HSPA5 acetylation in pancreatic cancer.
Wang Y, Liu Y, Wang C, Kang R, Tang D, Liu J
Scientific reports 2023 Sep 11;13(1):15004
Scientific reports 2023 Sep 11;13(1):15004
Upregulation of HDAC9 in hippocampal neurons mediates depression-like behaviours by inhibiting ANXA2 degradation.
Dai Y, Wei T, Huang Y, Bei Y, Lin H, Shen Z, Yu L, Yang M, Xu H, He W, Lin Z, Dai H
Cellular and molecular life sciences : CMLS 2023 Sep 10;80(10):289
Cellular and molecular life sciences : CMLS 2023 Sep 10;80(10):289
FAT4 overexpression promotes antitumor immunity by regulating the β-catenin/STT3/PD-L1 axis in cervical cancer.
Wang D, Wu S, He J, Sun L, Zhu H, Zhang Y, Liu S, Duan X, Wang Y, Xu T
Journal of experimental & clinical cancer research : CR 2023 Sep 1;42(1):222
Journal of experimental & clinical cancer research : CR 2023 Sep 1;42(1):222
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production.
Yao X, Liu H, Wang Z, Lu F, Chen W, Feng Q, Miao Y, Zhang J, Wang Y, Chen Y, Xue L, Liu Y, Chen L, Zhang Q
Oncogene 2023 Oct;42(43):3206-3218
Oncogene 2023 Oct;42(43):3206-3218
Antigenic variation in hemagglutinin-neuraminidase of Newcastle disease virus isolated from Tibet, China.
Chang Z, Dong X, Guan Z, Lu K, Chen X, Wei X, Guo H, Dang R, Wang J, Wang X, Xiao S, Yang Z, Liu H
Veterinary microbiology 2023 Oct;285:109872
Veterinary microbiology 2023 Oct;285:109872
Glycogen synthase kinase 3 controls T-cell exhaustion by regulating NFAT activation.
Fu Y, Wang J, Liu C, Liao K, Gao X, Tang R, Fan B, Hong Y, Xiao N, Xiao C, Liu WH
Cellular & molecular immunology 2023 Oct;20(10):1127-1139
Cellular & molecular immunology 2023 Oct;20(10):1127-1139
CALHM2 V136G polymorphism reduces astrocytic ATP release and is associated with depressive symptoms and Alzheimer's disease risk.
Liao Y, Wang Y, Tao QQ, Yang C, Wang J, Cheng J, Ma J, Wu ZY, Pan RY, Yuan Z
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Oct;19(10):4407-4420
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Oct;19(10):4407-4420
Acetyl-coenzyme A acetyltransferase 1 promotes brown adipogenesis by activating the AMPK-PGC1α signaling pathway.
Zhu K, Ni L, Han J, Yan Z, Zhang Y, Wang F, Wang L, Yang X
Biochimica et biophysica acta. Molecular and cell biology of lipids 2023 Oct;1868(10):159369
Biochimica et biophysica acta. Molecular and cell biology of lipids 2023 Oct;1868(10):159369
A high-throughput Gaussia luciferase reporter assay for screening potential gasdermin E activators against pancreatic cancer.
Liu Y, Zhang X, Zhang P, He T, Zhang W, Ma D, Li P, Chen J
Acta pharmaceutica Sinica. B 2023 Oct;13(10):4253-4272
Acta pharmaceutica Sinica. B 2023 Oct;13(10):4253-4272
Plasma exosomes induce inflammatory immune response in patients with acute myocardial infarction.
Gong Z, Wen M, Zhang W, Yu L, Huang C, Xu Y, Xia Z, Xu M, Xu J, Liang Q, Bao H, Cheng X
Archives of physiology and biochemistry 2023 Oct;129(5):1168-1176
Archives of physiology and biochemistry 2023 Oct;129(5):1168-1176
Dihydromyricetin confers cerebroprotection against subarachnoid hemorrhage via the Nrf2-dependent Prx2 signaling cascade.
Li XJ, Pang C, Peng Z, Zhuang Z, Lu Y, Li W, Zhang HS, Zhang XS, Hang CH
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:154997
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:154997
Elucidating the pharmacological effects of Compound Kushen injection on MYC-P15-CCND1 signaling pathway in nasopharyngeal carcinoma - An in vitro study.
Wu Z, Wu C, Shi J, Huang Z, Lu S, Tan Y, You R, Hai L, Huang J, Guo S, Gao Y, Jin Z, Tao X, You L, Wu J
Journal of ethnopharmacology 2023 Oct 28;315:116702
Journal of ethnopharmacology 2023 Oct 28;315:116702
Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.
Wang M, Tang J, Zhang S, Pang K, Zhao Y, Liu N, Huang J, Kang J, Dong S, Li H, Tian Z, Duan B, Lu F, Zhang W
Cell death discovery 2023 Oct 24;9(1):394
Cell death discovery 2023 Oct 24;9(1):394
Identification and development of Tetra-ARMS PCR-based screening test for a genetic variant of OLA1 (Tyr254Cys) in the human failing heart.
Dubey PK, Dubey S, Singh S, Bhat PD, Pogwizd S, Krishnamurthy P
medRxiv : the preprint server for health sciences 2023 Oct 19;
medRxiv : the preprint server for health sciences 2023 Oct 19;
Suppression of the gut microbiota-bile acid-FGF19 axis in patients with atrial fibrillation.
Zuo K, Fang C, Gao Y, Fu Y, Wang H, Li J, Zhong J, Yang X, Xu L
Cell proliferation 2023 Nov;56(11):e13488
Cell proliferation 2023 Nov;56(11):e13488
GPR37 promotes colorectal cancer liver metastases by enhancing the glycolysis and histone lactylation via Hippo pathway.
Zhou J, Xu W, Wu Y, Wang M, Zhang N, Wang L, Feng Y, Zhang T, Wang L, Mao A
Oncogene 2023 Nov;42(45):3319-3330
Oncogene 2023 Nov;42(45):3319-3330
C-IGF1R encoded by cIGF1R acts as a molecular switch to restrict mitophagy of drug-tolerant persister tumour cells in non-small cell lung cancer.
Wang H, Liang Y, Zhang T, Yu X, Song X, Chen Y, Mao Q, Xia W, Chen B, Xu L, Dong G, Jiang F
Cell death and differentiation 2023 Nov;30(11):2365-2381
Cell death and differentiation 2023 Nov;30(11):2365-2381
Inhibition of ANXA2 activity attenuates epileptic susceptibility and GluA1 phosphorylation.
Ma L, Wu Q, Yuan J, Wang Y, Zhang P, Liu Q, Tan D, Liang M, Chen Y
CNS neuroscience & therapeutics 2023 Nov;29(11):3644-3656
CNS neuroscience & therapeutics 2023 Nov;29(11):3644-3656
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
Yuan Z, Li J, Zou X, Liu C, Lu J, Ni C, Tang L, Wu X, Yan F
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
Mulberry leaf flavonoids activate BAT and induce browning of WAT to improve type 2 diabetes via regulating the AMPK/SIRT1/PGC-1α signaling pathway.
Cheng L, Shi L, He C, Wang C, Lv Y, Li H, An Y, Duan Y, Dai H, Zhang H, Huang Y, Fu W, Sun W, Zhao B
Chinese journal of natural medicines 2023 Nov;21(11):812-829
Chinese journal of natural medicines 2023 Nov;21(11):812-829
Co-delivery of azithromycin and ibuprofen by ROS-responsive polymer nanoparticles synergistically attenuates the acute lung injury.
Muhammad W, Zhang Y, Zhu J, Xie J, Wang S, Wang R, Feng B, Zhou J, Chen W, Xu Y, Yao Q, Yu Y, Cao H, Gao C
Biomaterials advances 2023 Nov;154:213621
Biomaterials advances 2023 Nov;154:213621
FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation.
Tian T, Xie X, Yi W, Zhou Y, Xu Y, Wang Z, Zhang J, Lin M, Zhang R, Lv Z, Li X, Lv L, Xu Y
Cell reports 2023 Nov 28;42(11):113362
Cell reports 2023 Nov 28;42(11):113362
Lnc-PTCHD4-AS inhibits gastric cancer through MSH2-MSH6 dimerization and ATM-p53-p21 activation.
Wang J, Mi Y, Sun X, Xue X, Zhao H, Zhang M, Hu B, Bukhari I, Zheng P
Aging 2023 Nov 27;15(22):13558-13578
Aging 2023 Nov 27;15(22):13558-13578
PDK4 rescues high-glucose-induced senescent fibroblasts and promotes diabetic wound healing through enhancing glycolysis and regulating YAP and JNK pathway.
Ma Z, Ding Y, Ding X, Mou H, Mo R, Tan Q
Cell death discovery 2023 Nov 25;9(1):424
Cell death discovery 2023 Nov 25;9(1):424
PHD3 inhibits colon cancer cell metastasis through the occludin-p38 pathway.
Li Y, Yuan T, Zhang H, Liu S, Lun J, Guo J, Wang Y, Zhang Y, Fang J
Acta biochimica et biophysica Sinica 2023 Nov 25;55(11):1749-1757
Acta biochimica et biophysica Sinica 2023 Nov 25;55(11):1749-1757
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
Cheng Z, Wang H, Yang Z, Li J, Chen X
BMC cancer 2023 Nov 20;23(1):1128
BMC cancer 2023 Nov 20;23(1):1128
Screening UFMylation-associated genes in heart tissues of Ufm1-transgenic mice.
Jiajia H, Ziyao Y, Jiaqi Z, Yanli C, Xiaotao Z, Ming S
BMC cardiovascular disorders 2023 Nov 18;23(1):567
BMC cardiovascular disorders 2023 Nov 18;23(1):567
Dopamine and cyclic adenosine monophosphate-regulated phosphoprotein with an apparent Mr of 32000 promotes colorectal cancer growth.
He K, Xie CZ, Li Y, Chen ZZ, Xu SH, Huang SQ, Yang JG, Wei ZQ, Peng XD
World journal of gastrointestinal oncology 2023 Nov 15;15(11):1936-1950
World journal of gastrointestinal oncology 2023 Nov 15;15(11):1936-1950
Lnc AC016727.1/BACH1/HIF-1 α signal loop promotes the progression of non-small cell lung cancer.
Zhang L, Liang J, Qin H, Lv Y, Liu X, Li Z, Chao Z, Jia C, Qin X, Zhang H
Journal of experimental & clinical cancer research : CR 2023 Nov 10;42(1):296
Journal of experimental & clinical cancer research : CR 2023 Nov 10;42(1):296
Activation of LXRα attenuates 2-Ethylhexyl diphenyl phosphate (EHDPP) induced placental dysfunction.
Zhang Y, Liang J, Gu H, Du T, Xu P, Yu T, He Q, Huang Z, Lei S, Li J
Ecotoxicology and environmental safety 2023 Nov 1;266:115605
Ecotoxicology and environmental safety 2023 Nov 1;266:115605
Sevoflurane induces neurotoxic effects on developing neurons through the WNK1/NKCC1/Ca(2+) /Drp-1 signalling pathway.
Bai YF, Li WJ, Ji YW, An LX, Zhang L, Li JF
Clinical and experimental pharmacology & physiology 2023 May;50(5):393-402
Clinical and experimental pharmacology & physiology 2023 May;50(5):393-402
Discovery of a natural small-molecule AMP-activated kinase activator that alleviates nonalcoholic steatohepatitis.
Chen J, Xu L, Zhang XQ, Liu X, Zhang ZX, Zhu QM, Liu JY, Iqbal MO, Ding N, Shao CL, Wei MY, Gu YC
Marine life science & technology 2023 May;5(2):196-210
Marine life science & technology 2023 May;5(2):196-210
PGC-1α Affects Epileptic Seizures by Regulating Mitochondrial Fusion in Epileptic Rats.
Li D, Zhang L, Tuo J, Zhang F, Tai Z, Liu X, Qiu X, Zhang H, Yang J, Wang J, Luo Z, Xu Z
Neurochemical research 2023 May;48(5):1361-1369
Neurochemical research 2023 May;48(5):1361-1369
PDLIM3 supports hedgehog signaling in medulloblastoma by facilitating cilia formation.
Zhang J, Yang Y, Li X, Li G, Mizukami T, Liu Y, Wang Y, Xu G, Roder H, Zhang L, Yang ZJ
Cell death and differentiation 2023 May;30(5):1198-1210
Cell death and differentiation 2023 May;30(5):1198-1210
GNB1 promotes hepatocellular carcinoma progression by targeting BAG2 to activate P38/MAPK signaling.
Zhang X, Dong K, Zhang J, Kuang T, Luo Y, Yu J, Yu J, Wang W
Cancer science 2023 May;114(5):2001-2013
Cancer science 2023 May;114(5):2001-2013
CB2R activation ameliorates late adolescent chronic alcohol exposure-induced anxiety-like behaviors during withdrawal by preventing morphological changes and suppressing NLRP3 inflammasome activation in prefrontal cortex microglia in mice.
Li J, Wang H, Liu D, Li X, He L, Pan J, Shen Q, Peng Y
Brain, behavior, and immunity 2023 May;110:60-79
Brain, behavior, and immunity 2023 May;110:60-79
BACH1 deficiency prevents neointima formation and maintains the differentiated phenotype of vascular smooth muscle cells by regulating chromatin accessibility.
Guo J, Qiu J, Jia M, Li Q, Wei X, Li L, Pan Q, Jin J, Ge F, Ma S, He Y, Lin J, Li Y, Ma J, Jiang N, Zhi X, Jiang L, Zhang J, Osto E, Jing Q, Wang X, Meng D
Nucleic acids research 2023 May 22;51(9):4284-4301
Nucleic acids research 2023 May 22;51(9):4284-4301
IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma.
Zhang X, Wang G, Gong Y, Zhao L, Song P, Zhang H, Zhang Y, Ju H, Wang X, Wang B, Ren H, Zhu X, Dong Y
iScience 2023 May 19;26(5):106639
iScience 2023 May 19;26(5):106639
Estrogen-mediated oar-miR-485-5p targets PPP1R13B to regulate myoblast proliferation in sheep.
Liu S, Liu Z, Wang P, Li W, Zhao S, Liu Y, Chu M
International journal of biological macromolecules 2023 May 1;236:123987
International journal of biological macromolecules 2023 May 1;236:123987
VPS35 promotes cell proliferation via EGFR recycling and enhances EGFR inhibitors response in gastric cancer.
Yu J, Feng H, Sang Q, Li F, Chen M, Yu B, Xu Z, Pan T, Wu X, Hou J, Zhu Z, Yan C, Su L, Li J, Liu B
EBioMedicine 2023 Mar;89:104451
EBioMedicine 2023 Mar;89:104451
Stabilization of nuclear β-catenin by inhibiting KDM2A mediates cerebral ischemic tolerance.
Zuo Y, Zhan L, Wen H, Xue J, Tan Y, Sun W, Xu E
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22796
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22796
METTL3 promotes SMSCs chondrogenic differentiation by targeting the MMP3, MMP13, and GATA3.
Hu B, Zou X, Yu Y, Jiang Y, Xu H
Regenerative therapy 2023 Mar;22:148-159
Regenerative therapy 2023 Mar;22:148-159
IGF2 inhibits hippocampal over-activated microglia and alleviates depression-like behavior in LPS- treated male mice.
Guo D, Xu Y, Liu Z, Wang Y, Xu X, Li C, Li S, Zhang J, Xiong T, Cao W, Liang J
Brain research bulletin 2023 Mar;194:1-12
Brain research bulletin 2023 Mar;194:1-12
One Stone, Two Birds: A Peptide-Au(I) Infinite Coordination Supermolecule for the Confederate Physical and Biological Radiosensitization in Cancer Radiation Therapy.
Wang J, Zhao J, Ma F, Gong L, Lu Y, Xiao W, Tang H, Gao C, Chen Y, Ma J, Gao Z, Yan J, Han S
Small (Weinheim an der Bergstrasse, Germany) 2023 Mar;19(11):e2204238
Small (Weinheim an der Bergstrasse, Germany) 2023 Mar;19(11):e2204238
Artesunate, a new antimalarial clinical drug, exhibits potent anti-AML activity by targeting the ROS/Bim and TFRC/Fe(2+) pathways.
Liu Y, Li H, Luo Z, Yu Y, Yang J, Zhang M, Law BYK, Huang Z, Li W
British journal of pharmacology 2023 Mar;180(6):701-720
British journal of pharmacology 2023 Mar;180(6):701-720
Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage.
Qiu X, Tao Q, Zhang L, Kuang C, Xie Y, Zhang L, Yin S, Peng J, Jiang Y
Journal of neurochemistry 2023 Mar;164(6):829-846
Journal of neurochemistry 2023 Mar;164(6):829-846
Key domains and residues of the receptor MRGPRX1 recognizing the peptide ligand BAM8-22.
Hu J, Wang L, Yang H, Meng Y, Tao M, Wu Y, Cao Z
Peptides 2023 Mar;161:170927
Peptides 2023 Mar;161:170927
LncRNA SPRY4-IT1 facilitates cell proliferation and angiogenesis of glioma via the miR-101-3p/EZH2/VEGFA signaling axis.
Wang J, Chen Y, Wang Q, Xu H, Jiang Q, Wang M, Li S, Chen Y, Wu C, Yu P, Xiao Z, Chen W, Lan Q
Cancer medicine 2023 Mar;12(6):7309-7326
Cancer medicine 2023 Mar;12(6):7309-7326
PKCθ Regulates Pituitary Adenoma Bone Invasion by Activating Osteoclast in NF-κB/IL-1β-Dependent Manner.
Wang Q, Lei Z, Wang Z, Jiang Q, Zhang Z, Liu X, Xing B, Li S, Guo X, Liu Y, Li X, Shu K, Zhang H, Huang Y, Lei T
Cancers 2023 Mar 6;15(5)
Cancers 2023 Mar 6;15(5)
Deletion of Transglutaminase 2 from Mouse Astrocytes Significantly Improves Their Ability to Promote Neurite Outgrowth on an Inhibitory Matrix.
Emerson J, Delgado T, Girardi P, Johnson GVW
International journal of molecular sciences 2023 Mar 23;24(7)
International journal of molecular sciences 2023 Mar 23;24(7)
PDCD6 Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis through the AKT/GSK3β/β-catenin Pathway.
Wen SY, Liu YT, Wei BY, Ma JQ, Chen YY
Biomedical and environmental sciences : BES 2023 Mar 20;36(3):241-252
Biomedical and environmental sciences : BES 2023 Mar 20;36(3):241-252
1,2,4,5-Tetrazine-tethered probes for fluorogenically imaging superoxide in live cells with ultrahigh specificity.
Jiang X, Li M, Wang Y, Wang C, Wang Y, Shen T, Shen L, Liu X, Wang Y, Li X
Nature communications 2023 Mar 14;14(1):1401
Nature communications 2023 Mar 14;14(1):1401
Mechanism Repositioning Based on Integrative Pharmacology: Anti-Inflammatory Effect of Safflower in Myocardial Ischemia-Reperfusion Injury.
Zhao F, Jiang H, Zhang T, Chen H, Li W, Li X, Wang P, Xu H
International journal of molecular sciences 2023 Mar 10;24(6)
International journal of molecular sciences 2023 Mar 10;24(6)
Tibetan medicine Si-Wei-Qiang-Wei Powder ameliorates cholecystitis via inhibiting the production of pro-inflammatory cytokines and regulating the MAPK signaling pathway.
Zheng Z, Xiong H, Zhao Z, Zhou K, Fu M, Liu X, Mei Z
Journal of ethnopharmacology 2023 Mar 1;303:116026
Journal of ethnopharmacology 2023 Mar 1;303:116026
Decellularized brain extracellular matrix slice glioblastoma culture model recapitulates the interaction between cells and the extracellular matrix without a nutrient-oxygen gradient interference.
Wang C, Zhao Q, Zheng X, Li S, Chen J, Zhao H, Chen F, Cui L, Li W
Acta biomaterialia 2023 Mar 1;158:132-150
Acta biomaterialia 2023 Mar 1;158:132-150
The tick saliva peptide HIDfsin2 promotes the tick-borne virus SFTSV replication in vitro by enhancing p38 signal pathway.
Wang L, Sun F, Hu J, Zuo W, Zheng Y, Wu Y, Kwok HF, Cao Z
Archives of toxicology 2023 Jun;97(6):1783-1794
Archives of toxicology 2023 Jun;97(6):1783-1794
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.
Li K, Feng Z, Wang L, Ma X, Wang L, Liu K, Geng X, Peng C
Inflammation 2023 Jun;46(3):1061-1076
Inflammation 2023 Jun;46(3):1061-1076
Magnify is a universal molecular anchoring strategy for expansion microscopy.
Klimas A, Gallagher BR, Wijesekara P, Fekir S, DiBernardo EF, Cheng Z, Stolz DB, Cambi F, Watkins SC, Brody SL, Horani A, Barth AL, Moore CI, Ren X, Zhao Y
Nature biotechnology 2023 Jun;41(6):858-869
Nature biotechnology 2023 Jun;41(6):858-869
Proteomics Profiling Reveals the Molecular Signatures and Potential Therapeutic Targets of Human Nasopharyngeal Carcinoma.
Fu Y, Liang X, Yang X, Liu J, Huang H, Zhang P, Li S, Zhu D, Zhang Y, Peng F, Chen Y, Chen Z
Molecular & cellular proteomics : MCP 2023 Jun;22(6):100567
Molecular & cellular proteomics : MCP 2023 Jun;22(6):100567
Chromatin remodeling and nucleoskeleton synergistically control osteogenic differentiation in different matrix stiffnesses.
Xu X, Zhang H, Li Y, Liu F, Jing Z, Ren M, Chen T, Fu Y, Wu Y, Ji P, Yang S
Materials today. Bio 2023 Jun;20:100661
Materials today. Bio 2023 Jun;20:100661
Amyloid futures in the expanding pathology of brain aging and dementia.
Thorwald MA, Silva J, Head E, Finch CE
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Jun;19(6):2605-2617
Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Jun;19(6):2605-2617
Ginsenoside Rb1 improves energy metabolism after spinal cord injury.
Wen S, Zou ZR, Cheng S, Guo H, Hu HS, Zeng FZ, Mei XF
Neural regeneration research 2023 Jun;18(6):1332-1338
Neural regeneration research 2023 Jun;18(6):1332-1338
Low rumen degradable starch promotes the growth performance of goats by increasing protein synthesis in skeletal muscle via the AMPK-mTOR pathway.
Liang Z, Jin C, Bai H, Liang G, Su X, Wang D, Yao J
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Jun;13:1-8
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Jun;13:1-8
Docosahexaenoic Acid Alters Lipid Metabolism Processes via H3K9ac Epigenetic Modification in Dairy Goat.
Wu J, Luo J, He Q, Xia Y, Tian H, Zhu L, Li C, Loor JJ
Journal of agricultural and food chemistry 2023 Jun 7;71(22):8527-8539
Journal of agricultural and food chemistry 2023 Jun 7;71(22):8527-8539
MiR-145 regulates steroidogenesis in mouse primary granulosa cells by targeting Arpc5 and subsequent cytoskeleton remodeling.
Ma L, Wang S, Yang J, Tang W, Wu Z, Cao L, Luo A, Fu F, Yang S, Wang S
The Journal of reproduction and development 2023 Jun 6;69(3):154-162
The Journal of reproduction and development 2023 Jun 6;69(3):154-162
Endothelial progenitor cell-derived exosomes promote anti-inflammatory macrophages via SOCS3/JAK2/STAT3 axis and improve the outcome of spinal cord injury.
Yuan F, Peng W, Yang Y, Xu J, Liu Y, Xie Y, Huang T, Shi C, Ding Y, Li C, Qin T, Xie S, Zhu F, Lu H, Huang J, Hu J
Journal of neuroinflammation 2023 Jun 30;20(1):156
Journal of neuroinflammation 2023 Jun 30;20(1):156
DnaJC7 specifically regulates tau seeding.
Perez VA, Sanders DW, Mendoza-Oliva A, Stopschinski BE, Mullapudi V, White CL, Joachimiak LA, Diamond MI
eLife 2023 Jun 30;12
eLife 2023 Jun 30;12
Tumor-Associated Fibroblast-Derived Exosomal circDennd1b Promotes Pituitary Adenoma Progression by Modulating the miR-145-5p/ONECUT2 Axis and Activating the MAPK Pathway.
Jiang Q, Lei Z, Wang Z, Wang Q, Zhang Z, Liu X, Xing B, Li S, Guo X, Liu Y, Li X, Qi Y, Shu K, Zhang H, Huang Y, Lei T
Cancers 2023 Jun 27;15(13)
Cancers 2023 Jun 27;15(13)
FBXO28 promotes proliferation, invasion, and metastasis of pancreatic cancer cells through regulation of SMARCC2 ubiquitination.
Liu S, Liu P, Zhu C, Yang R, He Z, Li Y, Li Y, Fei X, Hou J, Wang X, Pan Y
Aging 2023 Jun 21;15(12):5381-5398
Aging 2023 Jun 21;15(12):5381-5398
Scarless wound healing programmed by core-shell microneedles.
Zhang Y, Wang S, Yang Y, Zhao S, You J, Wang J, Cai J, Wang H, Wang J, Zhang W, Yu J, Han C, Zhang Y, Gu Z
Nature communications 2023 Jun 10;14(1):3431
Nature communications 2023 Jun 10;14(1):3431
Hydrogen sulfide antagonizes formaldehyde-induced ferroptosis via preventing ferritinophagy by upregulation of GDF11 in HT22 cells.
Tang YH, Wu L, Huang HL, Zhang PP, Zou W, Tang XQ, Tang YY
Toxicology 2023 Jun 1;491:153517
Toxicology 2023 Jun 1;491:153517
ORP8 inhibits renal cell carcinoma progression by accelerating Stathmin1 degradation and microtubule polymerization.
Zhang L, Pan Q, Wu Y, Zhang P, Li S, Xu Y, Li D, Zheng M, Pei D, Wang Q
Experimental cell research 2023 Jun 1;427(1):113601
Experimental cell research 2023 Jun 1;427(1):113601
Exosomes derived from oral squamous cell carcinoma tissue accelerate diabetic wound healing.
Zhang M, Guo J, Xiang K, Chen J, Wang C, Jiang T, Kang Y, Xu X, Li J, Yang X, Chen Z
American journal of physiology. Cell physiology 2023 Jun 1;324(6):C1307-C1319
American journal of physiology. Cell physiology 2023 Jun 1;324(6):C1307-C1319
The distinct initiation sites and processing activities of TTLL4 and TTLL7 in glutamylation of brain tubulin.
Zhang X, Li X, Chen W, Wang Y, Diao L, Gao Y, Wang H, Bao L, Liang X, Wu HY
The Journal of biological chemistry 2023 Jul;299(7):104923
The Journal of biological chemistry 2023 Jul;299(7):104923
MRPL51 is a downstream target of FOXM1 in promoting the malignant behaviors of lung adenocarcinoma.
Zhang W, Yu L, Xu C, Tang T, Cao J, Chen L, Pang X, Ren W
Oncology letters 2023 Jul;26(1):298
Oncology letters 2023 Jul;26(1):298
Anisomycin inhibits Coxsackievirus B replication by promoting the lysosomal degradation of eEF1A1.
Shao E, Zhao S, Dong Y, Wang Y, Fei Y, Li S, Wang L, Bashir T, Luan T, Lin L, Wang Y, Zhao W, Zhong Z
Antiviral research 2023 Jul;215:105621
Antiviral research 2023 Jul;215:105621
TANGO1 interacts with NRTN to promote hepatocellular carcinoma progression by regulating the PI3K/AKT/mTOR signaling pathway.
Man J, Zhou W, Zuo S, Zhao X, Wang Q, Ma H, Li HY
Biochemical pharmacology 2023 Jul;213:115615
Biochemical pharmacology 2023 Jul;213:115615
Neotuberostemonine and tuberostemonine ameliorate pulmonary fibrosis through suppressing TGF-β and SDF-1 secreted by macrophages and fibroblasts via the PI3K-dependent AKT and ERK pathways.
Fu S, Song X, Hu Y, Zhu Q, Lv X, Tang X, Zhang M
Chinese journal of natural medicines 2023 Jul;21(7):527-539
Chinese journal of natural medicines 2023 Jul;21(7):527-539
Hydrogen sulfide alleviates mitochondrial damage and ferroptosis by regulating OPA3-NFS1 axis in doxorubicin-induced cardiotoxicity.
Wang Y, Ying X, Wang Y, Zou Z, Yuan A, Xiao Z, Geng N, Qiao Z, Li W, Lu X, Pu J
Cellular signalling 2023 Jul;107:110655
Cellular signalling 2023 Jul;107:110655
Tumor necrosis factor-α reduces adiponectin production by decreasing transcriptional activity of peroxisome proliferator-activated receptor-γ in calf adipocytes.
Yu H, Gao X, Ge Q, Tai W, Hao X, Shao Q, Fang Z, Chen M, Song Y, Gao W, Liu G, Du X, Li X
Journal of dairy science 2023 Jul;106(7):5182-5195
Journal of dairy science 2023 Jul;106(7):5182-5195
Expression and Activity of the Transcription Factor CCAAT/Enhancer-Binding Protein β (C/EBPβ) Is Regulated by Specific Pulse-Modulated Radio Frequencies in Oligodendroglial Cells.
Huang B, Zhao W, Cai X, Zhu Y, Lu Y, Zhao J, Xiang N, Wang X, Deng H, Tang X, Liu L, Zhao Y, Shi Y
International journal of molecular sciences 2023 Jul 5;24(13)
International journal of molecular sciences 2023 Jul 5;24(13)
Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer.
Li X, Li F, Ye F, Guo H, Chen W, Jin J, Wang Y, Dai P, Shi H, Tao H, Dang W, Ding Y, Wang M, Jiang H, Chen K, Zhang N, Gao D, Zhang Y, Luo C
Cell reports 2023 Jul 25;42(7):112798
Cell reports 2023 Jul 25;42(7):112798
αKG-driven RNA polymerase II transcription of cyclin D1 licenses malic enzyme 2 to promote cell-cycle progression.
Yang Y, Zhang Z, Li W, Si Y, Li L, Du W
Cell reports 2023 Jul 25;42(7):112770
Cell reports 2023 Jul 25;42(7):112770
Neobavaisoflavone induces pyroptosis of liver cancer cells via Tom20 sensing the activated ROS signal.
Li Y, Zhao R, Xiu Z, Yang X, Zhu Y, Han J, Li S, Li Y, Sun L, Li X, Jin N, Li Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154869
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154869
Transcriptional analysis of the expression and prognostic value of lipid droplet-localized proteins in hepatocellular carcinoma.
Zhang Y, Liang X, Lian Q, Liu L, Zhang B, Dong Z, Liu K
BMC cancer 2023 Jul 18;23(1):677
BMC cancer 2023 Jul 18;23(1):677
Triptolide with hepatotoxicity and nephrotoxicity used in local delivery treatment of myocardial infarction by thermosensitive hydrogel.
Wang K, Zhu K, Zhu Z, Shao F, Qian R, Wang C, Dong H, Li Y, Gao Z, Zhao J
Journal of nanobiotechnology 2023 Jul 17;21(1):227
Journal of nanobiotechnology 2023 Jul 17;21(1):227
PPARα is involved in high-fat diet-induced risk avoidance impairment via the regulation of hippocampal BDNF.
Zhu XY, Luo J, Wei XJ, Pan LH, Xu XF, Hu LB, Dong YB, Jiang YK, Dong FY, Xu L, Xu LM, Liu AM, Zhang XQ
Food & function 2023 Jul 17;14(14):6541-6553
Food & function 2023 Jul 17;14(14):6541-6553
Small intestine submucosa as a growth factor attractor promotes peripheral nerve regeneration by enhancing syndecan-3/glial cell line-derived neurotrophic factor (GDNF) signalling:in vivostudy().
Liu CH, Chu YH, Chen YH, Chiang YH, Chen YH, Ku CY, Hsu MY, Lee YJ, Yang MY, Liao WC
Biomedical materials (Bristol, England) 2023 Jul 12;18(5)
Biomedical materials (Bristol, England) 2023 Jul 12;18(5)
Resveratrol-loaded macrophage exosomes alleviate multiple sclerosis through targeting microglia.
Zheng X, Sun K, Liu Y, Yin X, Zhu H, Yu F, Zhao W
Journal of controlled release : official journal of the Controlled Release Society 2023 Jan;353:675-684
Journal of controlled release : official journal of the Controlled Release Society 2023 Jan;353:675-684
Dexmedetomidine attenuates airway inflammation and oxidative stress in asthma via the Nrf2 signaling pathway.
Xiao S, Zhou Y, Gao H, Yang D
Molecular medicine reports 2023 Jan;27(1)
Molecular medicine reports 2023 Jan;27(1)
Inhibition of deubiquitinase USP28 attenuates cyst growth in autosomal dominant polycystic kidney disease.
Ren Y, Zhu X, Fu K, Zhang H, Zhao W, Lin Y, Fang Q, Wang J, Chen Y, Guo D
Biochemical pharmacology 2023 Jan;207:115355
Biochemical pharmacology 2023 Jan;207:115355
MUC1 promotes glioblastoma progression and TMZ resistance by stabilizing EGFRvIII.
Tong F, Zhao JX, Fang ZY, Cui XT, Su DY, Liu X, Zhou JH, Wang GX, Qiu ZJ, Liu SZ, Fu JQ, Kang CS, Wang JC, Wang QX
Pharmacological research 2023 Jan;187:106606
Pharmacological research 2023 Jan;187:106606
Pine pollen extract alleviates ethanol-induced oxidative stress and apoptosis in HepG2 cells via MAPK signaling.
Ma D, Wang Z, He Z, Wang Z, Chen Q, Qin F, Zeng M, Chen J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jan;171:113550
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jan;171:113550
Zcf24, a zinc-finger transcription factor, is required for lactate catabolism and inhibits commensalism in Candida albicans.
Sun Q, Dong B, Yang D, Yu J, Ren T, Wang T, Yang L, Lu Y, Su C
Molecular microbiology 2023 Jan;119(1):112-125
Molecular microbiology 2023 Jan;119(1):112-125
Low-Dose Radiation Reduces Doxorubicin-Induced Myocardial Injury Through Mitochondrial Pathways.
Zhao D, Jiang X, Meng X, Liu D, Du Y, Zhao L, Jiang H
Dose-response : a publication of International Hormesis Society 2023 Jan-Mar;21(1):15593258231155789
Dose-response : a publication of International Hormesis Society 2023 Jan-Mar;21(1):15593258231155789
Transcription factor ETS proto-oncogene 1 contributes to neuropathic pain by regulating histone deacetylase 1 in primary afferent neurons.
Zheng HL, Sun SY, Jin T, Zhang M, Zeng Y, Liu Q, Yang K, Wei R, Pan Z, Lin F
Molecular pain 2023 Jan-Dec;19:17448069231152125
Molecular pain 2023 Jan-Dec;19:17448069231152125
Exosomal-miR-129-2-3p derived from Fusobacterium nucleatum-infected intestinal epithelial cells promotes experimental colitis through regulating TIMELESS-mediated cellular senescence pathway.
Wei S, Wu X, Chen M, Xiang Z, Li X, Zhang J, Dong W
Gut microbes 2023 Jan-Dec;15(1):2240035
Gut microbes 2023 Jan-Dec;15(1):2240035
Resveratrol Modulates the Redox Response and Bile Acid Metabolism to Maintain the Cholesterol Homeostasis in Fish Megalobrama amblycephala Offered a High-Carbohydrate Diet.
Ge Y, Zhang L, Chen W, Sun M, Liu W, Li X
Antioxidants (Basel, Switzerland) 2023 Jan 3;12(1)
Antioxidants (Basel, Switzerland) 2023 Jan 3;12(1)
Network Pharmacology and Experimental Verification to Unveil the Mechanism of N-Methyl-D-Aspartic Acid Rescue Humantenirine-Induced Excitotoxicity.
Qi XJ, Huang CY, Zuo MT, Gong MD, Huang SJ, Tang MH, Liu ZY
Metabolites 2023 Jan 28;13(2)
Metabolites 2023 Jan 28;13(2)
Marine-Derived Natural Product HDYL-GQQ-495 Targets P62 to Inhibit Autophagy.
Li Q, Fan J, Chen Y, Liu Y, Liu H, Jiang W, Li D, Dang Y
Marine drugs 2023 Jan 20;21(2)
Marine drugs 2023 Jan 20;21(2)
Jatrorrhizine Suppresses Murine-Norovirus-Triggered N-GSDMD-Dependent Pyroptosis in RAW264.7 Macrophages.
Fu M, Chen N, Zhou Y, Chen S, Xu W, Gong S, Geng L
Vaccines 2023 Jan 12;11(1)
Vaccines 2023 Jan 12;11(1)
Anti-inflammatory and osteoprotective effects of Shi-Wei-Ru-Xiang pills on collagen-induced arthritis in rats via inhibiting MAPK and STAT3 pathways.
Xiong H, Meng F, Luo M, Chen W, Tian J, Chen L, Ju Y, Mei Z
Journal of ethnopharmacology 2023 Jan 10;300:115693
Journal of ethnopharmacology 2023 Jan 10;300:115693
Polydopamine-Decorated PLCL Conduit to Induce Synergetic Effect of Electrical Stimulation and Topological Morphology for Peripheral Nerve Regeneration.
Lu S, Chen W, Wang J, Guo Z, Xiao L, Wei L, Yu J, Yuan Y, Chen W, Bian M, Huang L, Liu Y, Zhang J, Li YL, Jiang LB
Small methods 2023 Feb;7(2):e2200883
Small methods 2023 Feb;7(2):e2200883
Zinc Promotes Spinal Cord Injury Recovery by Blocking the Activation of NLRP3 Inflammasome Through SIRT3-Mediated Autophagy.
Xu C, Zhou Z, Zhao H, Lin S, Zhang P, Tian H, Mei X
Neurochemical research 2023 Feb;48(2):435-446
Neurochemical research 2023 Feb;48(2):435-446
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
Wang J, Xu J, Dong Y, Su Z, Su H, Cheng Q, Liu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
3, 14, 19-Triacetyl Andrographolide alleviates the cognitive dysfunction of 3 × Tg-AD mice by inducing initiation and promoting degradation process of autophagy.
Zhang H, Xie X, Shi J, Zhao Q, Luo D, Hao J, Zhou Y, Han G, Pang X
Phytotherapy research : PTR 2023 Feb;37(2):410-423
Phytotherapy research : PTR 2023 Feb;37(2):410-423
Mechanism of YY1 mediating autophagy dependent ferroptosis in PM2.5 induced cardiac fibrosis.
Hu H, Li L, Zhang H, Zhang Y, Liu Q, Chen M, Ning J, Pang Y, Hu W, Niu Y, Zhang R
Chemosphere 2023 Feb;315:137749
Chemosphere 2023 Feb;315:137749
Collagen type Ⅰ-loaded methacrylamide hyaluronic acid hydrogel microneedles alleviate stress urinary incontinence in mice: A novel treatment and prevention strategy.
Zhang S, Yang L, Hong S, Liu J, Cheng J, He Y, Hong L
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113085
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113085
Bacterial infection promotes tumorigenesis of colorectal cancer via regulating CDC42 acetylation.
Wang DN, Ni JJ, Li JH, Gao YQ, Ni FJ, Zhang ZZ, Fang JY, Lu J, Yao YF
PLoS pathogens 2023 Feb;19(2):e1011189
PLoS pathogens 2023 Feb;19(2):e1011189
Mutation of the attractin gene impairs working memory in rats.
Liu MQ, Xue C, Li XH, Ding HQ, Zhang MY, Chen K, Li Y, Gao SZ, Xu XJ, Zhang WN
Brain and behavior 2023 Feb;13(2):e2876
Brain and behavior 2023 Feb;13(2):e2876
Revealing active components and action mechanism of Fritillariae Bulbus against non-small cell lung cancer through spectrum-effect relationship and proteomics.
Liu FJ, Chen XY, Yang J, Zhao Z, Wang QL, Li P, Jiang Y, Li HJ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Feb;110:154635
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Feb;110:154635
TIPE2 deletion improves the therapeutic potential of adoptively transferred NK cells.
Bi J, Huang C, Jin X, Zheng C, Huang Y, Zheng X, Tian Z, Sun H
Journal for immunotherapy of cancer 2023 Feb;11(2)
Journal for immunotherapy of cancer 2023 Feb;11(2)
Baricitinib Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice by Inhibiting TGF-β1 Signaling Pathway.
Gu S, Liang J, Zhang J, Liu Z, Miao Y, Wei Y, Li S, Gu J, Cui Y, Xiao T, Li X, Yang C
Molecules (Basel, Switzerland) 2023 Feb 27;28(5)
Molecules (Basel, Switzerland) 2023 Feb 27;28(5)
Peroxiredoxin-6 Released by Astrocytes Contributes to Neuroapoptosis During Ischemia.
Hou JY, Zhou XL, Wang XY, Liang J, Xue Q
Neuroscience 2023 Feb 21;512:59-69
Neuroscience 2023 Feb 21;512:59-69
Site-specific phosphorylation of tau impacts mitochondrial biology and response to stressors.
Isei MO, Girardi PA, Rodwell-Bullock J, Nehrke K, Johnson GV
bioRxiv : the preprint server for biology 2023 Feb 19;
bioRxiv : the preprint server for biology 2023 Feb 19;
SECTM1 is upregulated in immuno-hot tumors and predicts immunotherapeutic efficacy in multiple cancers.
Mei J, Fu Z, Cai Y, Song C, Zhou J, Zhu Y, Mao W, Xu J, Yin Y
iScience 2023 Feb 17;26(2):106027
iScience 2023 Feb 17;26(2):106027
Hyperactivation of TRPV4 causes the hippocampal pyroptosis pathway and results in cognitive impairment in LPS-treated mice.
Guo D, Xu Y, Wang Y, Zhong X, Liu Z, Li S, Xu X, Zhang J, Xiong T, Cao W, Liang J
Behavioural brain research 2023 Feb 15;439:114223
Behavioural brain research 2023 Feb 15;439:114223
Design, synthesis and biological evaluation of novel phenylfuran-bisamide derivatives as P-glycoprotein inhibitors against multidrug resistance in MCF-7/ADR cell.
Yang Z, Yang X, Li Y, Cai Y, Yu Y, Zhuang W, Sun X, Li Q, Bao X, Ye X, Tian J, Wei B, Chen J, Wu Q, Zhang H, Mou X, Wang H
European journal of medicinal chemistry 2023 Feb 15;248:115092
European journal of medicinal chemistry 2023 Feb 15;248:115092
microRNA-627-5p inhibits colorectal cancer cell proliferation, migration and invasion by targeting Wnt2.
Zhao DY, Yin TF, Sun XZ, Zhou YC, Wang QQ, Zhou GY, Yao SK
World journal of gastrointestinal oncology 2023 Feb 15;15(2):318-331
World journal of gastrointestinal oncology 2023 Feb 15;15(2):318-331
A Novel Prenylflavonoid Icariside I Ameliorates Estrogen Deficiency-Induced Osteoporosis via Simultaneous Regulation of Osteoblast and Osteoclast Differentiation.
Chen C, Wu M, Lei H, Cao Z, Wu F, Song Y, Zhang C, Qin M, Zhang C, Du R, Zhou J, Lu Y, Xie D, Zhang L
ACS pharmacology & translational science 2023 Feb 10;6(2):270-280
ACS pharmacology & translational science 2023 Feb 10;6(2):270-280
Si-Ni-SAN ameliorates obesity through AKT/AMPK/HSL pathway-mediated lipolysis: Network pharmacology and experimental validation.
Li J, Wu K, Zhong Y, Kuang J, Huang N, Guo X, Du H, Guo C, Li R, Zhu X, Zhang T, Gong L, Sheng L, Sun R
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115892
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115892
UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.
Hong X, Ma N, Li D, Zhang M, Dong W, Huang J, Ci X, Zhang S
Cell death & disease 2023 Feb 10;14(2):100
Cell death & disease 2023 Feb 10;14(2):100
Knockout of transient receptor potential ankyrin 1 (TRPA1) modulates the glial phenotype and alleviates perihematomal neuroinflammation after intracerebral hemorrhage in mice via MAPK/NF-κB signaling.
Xia M, Chen YJ, Chen B, Ru X, Wang J, Lin J, Tang X, Chen W, Hu R, Li W, Feng H
Neuroreport 2023 Feb 1;34(2):81-92
Neuroreport 2023 Feb 1;34(2):81-92
ADAMTS7-Mediated Complement Factor H Degradation Potentiates Complement Activation to Contributing to Renal Injuries.
Ma Z, Mao C, Jia Y, Yu F, Xu P, Tan Y, Zou QH, Zhou XJ, Kong W, Fu Y
Journal of the American Society of Nephrology : JASN 2023 Feb 1;34(2):291-308
Journal of the American Society of Nephrology : JASN 2023 Feb 1;34(2):291-308
TBC1 domain family member 25 protects against myocardial apoptosis and the proinflammatory response triggered by ischemia-reperfusion injury through suppression of the TAK1-JNK/p38 MAPK signaling cascade.
Liu Z, Shang F, Li N, Dong W
In vitro cellular & developmental biology. Animal 2023 Dec;59(10):796-810
In vitro cellular & developmental biology. Animal 2023 Dec;59(10):796-810
White adipose tissue-derived small extracellular vesicles: A new potential therapeutic reagent for accelerating diabetic wound healing.
Zhang C, Jiang T, Jiang G, Xu X, Yan C, Kang Y, Xiang X, Liu S, Nie P, Zhang M, Chen J, Yuan M, Xu Y, Yang X, Chen Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Dec;37(12):e23314
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Dec;37(12):e23314
Exogenous H(2) S promotes ubiquitin-mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S-sulfhydration.
Zhang S, Wang M, Li H, Li Q, Liu N, Dong S, Zhao Y, Pang K, Huang J, Ren C, Wang Y, Tian Z, Lu F, Zhang W
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2719-2732
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2719-2732
Phenylbutyrate and Dichloroacetate Enhance the Liquid-Stored Boar Sperm Quality via PDK1 and PDK3.
Guo Z, Zhang Y, Huang A, Ni Q, Zeng C
International journal of molecular sciences 2023 Dec 4;24(23)
International journal of molecular sciences 2023 Dec 4;24(23)
Succinate-induced macrophage polarization and RBP4 secretion promote vascular sprouting in ocular neovascularization.
Shen T, Lin R, Hu C, Yu D, Ren C, Li T, Zhu M, Wan Z, Su T, Wu Y, Cai W, Yu J
Journal of neuroinflammation 2023 Dec 21;20(1):308
Journal of neuroinflammation 2023 Dec 21;20(1):308
MRPL48 is a novel prognostic and predictive biomarker of hepatocellular carcinoma.
Lin YX, Pan JY, Feng WD, Huang TC, Li CZ
European journal of medical research 2023 Dec 14;28(1):589
European journal of medical research 2023 Dec 14;28(1):589
Piezo1 suppression reduces demyelination after intracerebral hemorrhage.
Qu J, Zong HF, Shan Y, Zhang SC, Guan WP, Yang Y, Zhao HL
Neural regeneration research 2023 Aug;18(8):1750-1756
Neural regeneration research 2023 Aug;18(8):1750-1756
MicroRNA‑30a‑5p regulates cypermethrin-induced apoptosis of Sertoli cells by targeting KLF9 in vitro.
Wang Q, Xie JF, Yao TT, Wang XX, Guo QW, Wang LS, Yu Y, Xu LC
Reproductive toxicology (Elmsford, N.Y.) 2023 Aug;119:108414
Reproductive toxicology (Elmsford, N.Y.) 2023 Aug;119:108414
MicroRNA-144-3p protects against chemotherapy-induced apoptosis of ovarian granulosa cells and activation of primordial follicles by targeting MAP3K9.
Liu M, Xiao B, Zhu Y, Chen M, Huang J, Guo H, Wang F
European journal of medical research 2023 Aug 3;28(1):264
European journal of medical research 2023 Aug 3;28(1):264
CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway.
Ji HZ, Chen L, Ren M, Li S, Liu TY, Chen HJ, Yu HH, Sun Y
Pharmaceuticals (Basel, Switzerland) 2023 Aug 25;16(9)
Pharmaceuticals (Basel, Switzerland) 2023 Aug 25;16(9)
LncRNA SOCS2-AS1 promotes the progression of papillary thyroid cancer by destabilizing p53 protein.
Zhang X, Zhang X, Yang G, Wan L, Yin F, Li H, Yin D
Biochemical and biophysical research communications 2023 Aug 20;669:95-102
Biochemical and biophysical research communications 2023 Aug 20;669:95-102
TM6SF2 reduces lipid accumulation in vascular smooth muscle cells by inhibiting LOX-1 and CD36 expression.
Li TT, Cui YT, Li TH, Xiang Q, Chen YY, Zheng XL, Peng J, Tang ZH
Experimental cell research 2023 Aug 15;429(2):113666
Experimental cell research 2023 Aug 15;429(2):113666
Progressive Thinning of Retinal Nerve Fiber Layer/Ganglion Cell Layer (RNFL/GCL) as Biomarker and Pharmacological Target of Diabetic Retinopathy.
Zerbini G, Maestroni S, Viganò I, Mosca A, Paleari R, Gabellini D, Galbiati S, Rama P
International journal of molecular sciences 2023 Aug 11;24(16)
International journal of molecular sciences 2023 Aug 11;24(16)
Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.
Zhang Y, Wang S, Dai X, Liu T, Liu Y, Shi H, Yin J, Xu T, Zhang Y, Zhao D, Sukhorukov V, Orekhov AN, Gao S, Wang L, Zhang D
Journal of ethnopharmacology 2023 Aug 10;312:116530
Journal of ethnopharmacology 2023 Aug 10;312:116530
Apolipoprotein E Polymorphism Impacts White Matter Injury Through Microglial Phagocytosis After Experimental Subarachnoid Hemorrhage.
Li C, Lu P, Zhang L, He Y, Zhang L, Yang L, Zhang F, Kong X, Tao Q, Zhou J, Wu J, Peng T, Xie B, Jiang Y, Peng J
Neuroscience 2023 Aug 1;524:220-232
Neuroscience 2023 Aug 1;524:220-232
Systemic treatment with GnRH agonist produces antidepressant-like effects in LPS induced depression male mouse model.
Xu Y, Li W, Shi M, Xu X, Guo D, Liu Z, Chen L, Zhong X, Cao W
Neuropharmacology 2023 Aug 1;233:109560
Neuropharmacology 2023 Aug 1;233:109560
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimer's Disease Pathogenesis.
Wang J, Cheng Q, Zhang Y, Hong C, Liu J, Liu X, Chang J
Aging and disease 2023 Aug 1;14(4):1458-1471
Aging and disease 2023 Aug 1;14(4):1458-1471
SIRT1 attenuates blood-spinal cord barrier disruption after spinal cord injury by deacetylating p66Shc.
Jiang T, Qin T, Gao P, Tao Z, Wang X, Wu M, Gu J, Chu B, Zheng Z, Yi J, Xu T, Huang Y, Liu H, Zhao S, Ren Y, Chen J, Yin G
Redox biology 2023 Apr;60:102615
Redox biology 2023 Apr;60:102615
In silico, in vitro and in vivo studies: Dibutyl phthalate promotes prostate cancer cell proliferation by activating Forkhead Box M1 and remission after Natura-α pretreatment.
Bu H, Tang S, Liu G, Miao C, Zhou X, Yang H, Liu B
Toxicology 2023 Apr;488:153465
Toxicology 2023 Apr;488:153465
Vagus nerve stimulation is a potential treatment for ischemic stroke.
Liu YL, Wang SR, Ma JX, Yu LH, Jia GW
Neural regeneration research 2023 Apr;18(4):825-831
Neural regeneration research 2023 Apr;18(4):825-831
Association between F-box-only protein 43 overexpression and hepatocellular carcinoma pathogenesis and prognosis.
Wu S, Qin L, Yang J, Wang J, Shen Y
Cancer medicine 2023 Apr;12(8):10062-10076
Cancer medicine 2023 Apr;12(8):10062-10076
Dual-specificity phosphatase 26-dificient neurons are susceptible to oxygen-glucose deprivation/reoxygenation-evoked apoptosis and proinflammatory response by affecting the TAK1-medaited JNK/P38 MAPK pathway.
Zhao H, Lv J, Meng L, Lv J, Li Z
International immunopharmacology 2023 Apr;117:109980
International immunopharmacology 2023 Apr;117:109980
The dichloromethane extract of Callicarpa longissima rich in diterpenoid phenols exerts anti-inflammatory effect via inhibiting the TLR4/NF-κB signaling pathway.
Li LC, Fu YX, Ning DS, Yu LL, Zou ZQ, Pan ZH
Journal of ethnopharmacology 2023 Apr 6;305:116124
Journal of ethnopharmacology 2023 Apr 6;305:116124
Enhanced E6AP-mediated ubiquitination of ENO1 via LINC00663 contributes to radiosensitivity of breast cancer by regulating mitochondrial homeostasis.
Ma J, Zhu J, Li J, Liu J, Kang X, Yu J
Cancer letters 2023 Apr 28;560:216118
Cancer letters 2023 Apr 28;560:216118
Novel Benzo Five-Membered Heterocycle Derivatives as P-Glycoprotein Inhibitors: Design, Synthesis, Molecular Docking, and Anti-Multidrug Resistance Activity.
Yang Z, Cai Y, Yang X, Li Y, Wu Q, Yu Y, Chen Z, Wei B, Tian JM, Bao X, Ye X, Chen J, Zhang H, Mou X, Sun X, Wang H
Journal of medicinal chemistry 2023 Apr 27;66(8):5550-5566
Journal of medicinal chemistry 2023 Apr 27;66(8):5550-5566
Acinous cell AR42J-derived exosome miR125b-5p promotes acute pancreatitis exacerbation by inhibiting M2 macrophage polarization via PI3K/AKT signaling pathway.
Zheng Z, Cao F, Ding YX, Lu JD, Fu YQ, Liu L, Guo YL, Liu S, Sun HC, Cui YQ, Li F
World journal of gastrointestinal surgery 2023 Apr 27;15(4):600-620
World journal of gastrointestinal surgery 2023 Apr 27;15(4):600-620
Targeting Chondroitin Sulphate Synthase 1 (Chsy1) Promotes Axon Growth Following Neurorrhaphy by Suppressing Versican Accumulation.
Liu CH, Ho YJ, Wang CY, Hsu CC, Chu YH, Hsu MY, Chen SJ, Hsiao WC, Liao WC
Molecules (Basel, Switzerland) 2023 Apr 26;28(9)
Molecules (Basel, Switzerland) 2023 Apr 26;28(9)
A conditional knockout rat resource of mitochondrial protein-coding genes via a DdCBE-induced premature stop codon.
Tan L, Qi X, Kong W, Jin J, Lu D, Zhang X, Wang Y, Wang S, Dong W, Shi X, Chen W, Wang J, Li K, Xie Y, Gao L, Guan F, Gao K, Li C, Wang C, Hu Z, Zhang L, Guo X, Shen B, Ma Y
Science advances 2023 Apr 14;9(15):eadf2695
Science advances 2023 Apr 14;9(15):eadf2695
Effects of Spatial Expression of Activating Transcription Factor 4 on the Pathogenicity of Two Phenotypes of Bovine Viral Diarrhea Virus by Regulating the Endoplasmic Reticulum-Mediated Autophagy Process.
Wang J, Chen KY, Wang SH, Liu Y, Zhao YQ, Yang L, Yang GH, Wang XJ, Zhu YH, Yin JH, Wang JF
Microbiology spectrum 2023 Apr 13;11(2):e0422522
Microbiology spectrum 2023 Apr 13;11(2):e0422522
ME2 Promotes Hepatocellular Carcinoma Cell Migration through Pyruvate.
Yang Y, Zhang Z, Li W, Li L, Zhou Y, Du W
Metabolites 2023 Apr 10;13(4)
Metabolites 2023 Apr 10;13(4)
TET1-TRPV4 Signaling Contributes to Bone Cancer Pain in Rats.
Xu ZH, Niu Z, Liu Y, Liu PL, Lin XL, Zhang L, Chen L, Song Y, Sun R, Zhang HL
Brain sciences 2023 Apr 10;13(4)
Brain sciences 2023 Apr 10;13(4)
Antidepressant-like effect of acute dose of Naringin involves suppression of NR1 and activation of protein kinase A/cyclic adenosine monophosphate response element-binding protein/brain-derived neurotrophic factor signaling in hippocampus.
Wang G, Yang H, Zuo W, Mei X
Behavioural pharmacology 2023 Apr 1;34(2-3):101-111
Behavioural pharmacology 2023 Apr 1;34(2-3):101-111
The preventive and therapeutic effect of repetitive transcranial magnetic stimulation on radiation-induced brain injury in mice.
Liu LY, Qin TZ, Guo L, Rong-Rong H, Jing YT, Lai PP, Xue YZ, Ding GR
International journal of radiation biology 2022;98(8):1316-1329
International journal of radiation biology 2022;98(8):1316-1329
Selective Inhibition of Histone Deacetylase Class IIa With MC1568 Ameliorates Podocyte Injury.
He X, Sun T, Zhang P, Xia Z, Gao C, Ren H, Ji D
Frontiers in medicine 2022;9:848938
Frontiers in medicine 2022;9:848938
Copy Number Analyses Identified a Novel Gene: APOBEC3A Related to Lipid Metabolism in the Pathogenesis of Preeclampsia.
Liu N, Guo YN, Wang XJ, Ma J, He YT, Zhang F, He H, Xie JL, Zhuang X, Liu M, Sun JH, Chen Y, Lin JH, Gong LK, Wang BS
Frontiers in cardiovascular medicine 2022;9:841249
Frontiers in cardiovascular medicine 2022;9:841249
Activation of Transcription Factor EB Is Associated With Adipose Tissue Lipolysis in Dairy Cows With Subclinical Ketosis.
Yu H, Gao X, Loor JJ, Jiang Q, Fang Z, Hao X, Shi Z, Fan M, Chen M, Li X, Liu G, Wang Z, Li X, Du X
Frontiers in veterinary science 2022;9:816064
Frontiers in veterinary science 2022;9:816064
The Hair Growth-Promoting Effect of Gardenia florida Fruit Extract and Its Molecular Regulation.
Liu X, Ji T, Hu H, Lv X, Zhu G
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8498974
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8498974
Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK.
Chen C, Chen Y, Liu T, Song D, Ma D, Cheng O
Oxidative medicine and cellular longevity 2022;2022:7511393
Oxidative medicine and cellular longevity 2022;2022:7511393
Epoxyeicosatrienoic Acids Inhibit the Activation of Murine Fibroblasts by Blocking the TGF-β1-Smad2/3 Signaling in a PPARγ-Dependent Manner.
Tao JH, Liu T, Zhang CY, Zu C, Yang HH, Liu YB, Yang JT, Zhou Y, Guan CX
Oxidative medicine and cellular longevity 2022;2022:7265486
Oxidative medicine and cellular longevity 2022;2022:7265486
Identifying Potential Tumor Antigens and Antigens-Related Subtypes in Hepatocellular Carcinoma for mRNA Vaccine Development.
Liao W, Shi Z, Tang H, Wu T, Zhang C, He Y, Zou R, Wang L
Journal of oncology 2022;2022:6851026
Journal of oncology 2022;2022:6851026
Dexpramipexole Attenuates White Matter Injury to Facilitate Locomotion and Motor Coordination Recovery via Reducing Ferroptosis after Intracerebral Hemorrhage.
Wang B, Zhang X, Zhong J, Wang S, Zhang C, Li M, Hu Q, Wang S, Chen L, Chen W, Ge H, Feng H
Oxidative medicine and cellular longevity 2022;2022:6160701
Oxidative medicine and cellular longevity 2022;2022:6160701
Extracellular CIRP Upregulates Proinflammatory Cytokine Expression via the NF-kappaB and ERK1/2 Signaling Pathways in Psoriatic Keratinocytes.
Zhang X, Wang S, Wang W, Song L, Feng S, Wang J, Kang T, Yang P, Wang N, Yang P, Bai R, Shao Y, Zheng Y
Mediators of inflammation 2022;2022:5978271
Mediators of inflammation 2022;2022:5978271
Metformin Protects against Spinal Cord Injury and Cell Pyroptosis via AMPK/NLRP3 Inflammasome Pathway.
Yuan Y, Fan X, Guo Z, Zhou Z, Gao W
Analytical cellular pathology (Amsterdam) 2022;2022:3634908
Analytical cellular pathology (Amsterdam) 2022;2022:3634908
Prediction of Prognosis and Recurrence of Bladder Cancer by ECM-Related Genes.
Zhao H, Chen Z, Fang Y, Su M, Xu Y, Wang Z, Gyamfi MA, Zhao J
Journal of immunology research 2022;2022:1793005
Journal of immunology research 2022;2022:1793005
Hyperhomocysteinemia Promotes Cardiac Hypertrophy in Hypertension.
Deng Y, Li Z, An X, Fan R, Wang Y, Li J, Yang X, Liao J, Xia Y
Oxidative medicine and cellular longevity 2022;2022:1486157
Oxidative medicine and cellular longevity 2022;2022:1486157
Repeated Yueju, But Not Fluoxetine, Induced Sustained Antidepressant Activity in a Mouse Model of Chronic Learned Helplessness: Involvement of CaMKII Signaling in the Hippocampus.
Zou Z, Huang J, Yang Q, Zhang Y, Xu B, Wang P, Chen G
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1442578
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1442578
Silencing lncRNA 93358 Inhibits the Apoptosis of Myocardial Cells in Myocardial Infarction Rats by Inducing the Expression of SLC8A1.
Cai J, Wang X, Liao W, Zhong Y, Chen L, Zhang Z
BioMed research international 2022;2022:1138709
BioMed research international 2022;2022:1138709
MiR-3571 modulates the proliferation and migration of vascular smooth muscle cells by targeting claudin 1.
Xie Y, Tan J, Qin Y, Cao Y, Wang Y, Li A, Wang Z, Qiao Z, Yan Z
International journal of medical sciences 2022;19(3):511-524
International journal of medical sciences 2022;19(3):511-524
Caspase-1-mediated extracellular vesicles derived from pyroptotic alveolar macrophages promote inflammation in acute lung injury.
Qin X, Zhou Y, Jia C, Chao Z, Qin H, Liang J, Liu X, Liu Z, Sun T, Yuan Y, Zhang H
International journal of biological sciences 2022;18(4):1521-1538
International journal of biological sciences 2022;18(4):1521-1538
Diprotin A TFA Exerts Neurovascular Protection in Ischemic Cerebral Stroke.
Zhou MY, Zhang YJ, Ding HM, Wu WF, Cai WW, Wang YQ, Geng DQ
Frontiers in neuroscience 2022;16:861059
Frontiers in neuroscience 2022;16:861059
Inhibiting Sphingosine 1-Phosphate Receptor Subtype 3 Attenuates Brain Damage During Ischemia-Reperfusion Injury by Regulating nNOS/NO and Oxidative Stress.
Fan X, Chen H, Xu C, Wang Y, Yin P, Li M, Tang Z, Jiang F, Wei W, Song J, Li G, Zhong D
Frontiers in neuroscience 2022;16:838621
Frontiers in neuroscience 2022;16:838621
BRD7 Stabilizes P53 via Dephosphorylation of MDM2 to Inhibit Tumor Growth in Breast Cancer Harboring Wild-type P53.
Luo Y, Wang X, Niu W, Zhou Y, Li M, Ma J, Yang J, Fan S, Zeng Z, Xiong W, Li X, Li G, Xiao J, Zhou M
Journal of Cancer 2022;13(5):1436-1448
Journal of Cancer 2022;13(5):1436-1448
Qing-Re-Xiao-Zheng-Yi-Qi formula relieves kidney damage and activates mitophagy in diabetic kidney disease.
Wu Q, Yan R, Yang H, Wang Y, Zhang C, Zhang J, Cui Z, Wang Y, Sun W
Frontiers in pharmacology 2022;13:992597
Frontiers in pharmacology 2022;13:992597
Therapeutic effects of shaogan fuzi decoction in rheumatoid arthritis: Network pharmacology and experimental validation.
Shi L, Zhao Y, Feng C, Miao F, Dong L, Wang T, Stalin A, Zhang J, Tu J, Liu K, Sun W, Wu J
Frontiers in pharmacology 2022;13:967164
Frontiers in pharmacology 2022;13:967164
Cuproptosis status affects treatment options about immunotherapy and targeted therapy for patients with kidney renal clear cell carcinoma.
Zhang G, Chen X, Fang J, Tai P, Chen A, Cao K
Frontiers in immunology 2022;13:954440
Frontiers in immunology 2022;13:954440
Optical Visualization of Red-GQDs' Organelles Distribution and Localization in Living Cells.
Hu H, Li P, Qiu J, Zhao M, Kuang M, Zhang Z, Wang D
Frontiers in pharmacology 2022;13:932807
Frontiers in pharmacology 2022;13:932807
ANXA1: An Important Independent Prognostic Factor and Molecular Target in Glioma.
Zhang D, Wang W, Zhou H, Su L, Han X, Zhang X, Han W, Wang Y, Xue X
Frontiers in genetics 2022;13:851505
Frontiers in genetics 2022;13:851505
Oar-miR-432 Regulates Fat Differentiation and Promotes the Expression of BMP2 in Ovine Preadipocytes.
Jin M, Fei X, Li T, Lu Z, Chu M, Di R, He X, Wang X, Wang Y, Yuan Z, Quan K, Wang H, Wei C
Frontiers in genetics 2022;13:844747
Frontiers in genetics 2022;13:844747
Sperm Autoantigenic Protein 17 Predicts the Prognosis and the Immunotherapy Response of Cancers: A Pan-Cancer Analysis.
Tu Z, Peng J, Long X, Li J, Wu L, Huang K, Zhu X
Frontiers in immunology 2022;13:844736
Frontiers in immunology 2022;13:844736
Sleeve Gastrectomy-Induced AMPK Activation Attenuates Diabetic Cardiomyopathy by Maintaining Mitochondrial Homeostasis via NR4A1 Suppression in Rats.
Li S, Dong S, Xu Q, Shi B, Li L, Zhang W, Zhu J, Cheng Y, Zhang G, Zhong M
Frontiers in physiology 2022;13:837798
Frontiers in physiology 2022;13:837798
S1PR3, as a Core Protein Related to Ischemic Stroke, is Involved in the Regulation of Blood-Brain Barrier Damage.
Fan X, Chen H, Xu C, Wang Y, Yin P, Li M, Tang Z, Jiang F, Wei W, Song J, Li G, Zhong D
Frontiers in pharmacology 2022;13:834948
Frontiers in pharmacology 2022;13:834948
Punicalagin Alleviates Psoriasis by Inhibiting NF-κB-Mediated IL-1β Transcription and Caspase-1-Regulated IL-1β Secretion.
Tang L, Li T, Zhang B, Zhang Z, Sun X, Zhu Y, Feng B, Su Z, Yang L, Li H, Liu H, Chen Y, Dai Z, Zheng X, Li M, Li C, Zhao J, Qiu X, Ye S, Liu H, Zheng G, Li B, Lu C
Frontiers in pharmacology 2022;13:817526
Frontiers in pharmacology 2022;13:817526
Avasimibe Alleviates Disruption of the Airway Epithelial Barrier by Suppressing the Wnt/β-Catenin Signaling Pathway.
Zhou Z, Liang S, Zhou Z, Liu J, Meng X, Zou F, Yu C, Cai S
Frontiers in pharmacology 2022;13:795934
Frontiers in pharmacology 2022;13:795934
Identification of super-enhancer-driven peptidyl arginine deiminases as potential biomarkers and therapeutic targets for osimertinib-resistant non-small cell lung cancer.
Li H, Muhetaer G, Xie Y, Yao K, Ma Q, Guan H, Xing S, Huang X, Zhou J
Frontiers in pharmacology 2022;13:1071365
Frontiers in pharmacology 2022;13:1071365
Small RNA perspective of physical exercise-related improvement of male reproductive dysfunction due to obesity.
Lin T, Zhang S, Zhou Y, Wu L, Liu X, Huang H
Frontiers in endocrinology 2022;13:1038449
Frontiers in endocrinology 2022;13:1038449
Berberine prevents lethal EV71 neurological infection in newborn mice.
Cui G, Wang H, Yang C, Zhou X, Wang J, Wang T, Ma T
Frontiers in pharmacology 2022;13:1027566
Frontiers in pharmacology 2022;13:1027566
X-box binding protein 1: A new metabolic mediator and drug target of metformin?
Lou K, Sun P, Zhang C, Jiang Q, Pang S
Frontiers in pharmacology 2022;13:1013218
Frontiers in pharmacology 2022;13:1013218
Prrx1 promotes resistance to temozolomide by upregulating ABCC1 and inducing vasculogenic mimicry in glioma.
Chen Z, Zhang Y, Chen Y, Lin W, Zhang Y, Cai G, Sun X, Zheng K, He J, Ai T, Wang J, Zhao L, Ke Y
American journal of cancer research 2022;12(8):3892-3912
American journal of cancer research 2022;12(8):3892-3912
Interleukin 33-mediated inhibition of A-type K(+) channels induces sensory neuronal hyperexcitability and nociceptive behaviors in mice.
Wang Y, Wang X, Qi R, Lu Y, Tao Y, Jiang D, Sun Y, Jiang X, Liu C, Zhang Y, Tao J
Theranostics 2022;12(5):2232-2247
Theranostics 2022;12(5):2232-2247
The PROTAC selectively degrading Bcl-x(L) represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while sparing bone growth.
Zhang S, Chen Y, Xu Z, Yang J, Sun R, Wang J, Sun Y, Jiang B, Yang X, Tan W
Theranostics 2022;12(17):7476-7490
Theranostics 2022;12(17):7476-7490
A novel HCC prognosis predictor PDSS1 affects the cell cycle through the STAT3 signaling pathway in HCC.
Rao Z, Li H, Yao W, Wang Q, Ma B, Xue D, Meng X
Frontiers in oncology 2022;12:927468
Frontiers in oncology 2022;12:927468
The Synergistic Cytotoxic Effects of GW5074 and Sorafenib by Impacting Mitochondrial Functions in Human Colorectal Cancer Cell Lines.
Hu JM, Chang YL, Hsieh CC, Huang SM
Frontiers in oncology 2022;12:925653
Frontiers in oncology 2022;12:925653
Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling Via Binding to Membrane Receptors LRP5/LRP6.
Wang H, Zhao S, Liu Y, Sun F, Huang X, Wu T
Frontiers in oncology 2022;12:898047
Frontiers in oncology 2022;12:898047
AQP5 Is a Novel Prognostic Biomarker in Pancreatic Adenocarcinoma.
Chen G, Song H, Yang Z, Du T, Zheng Y, Lu Z, Zhang K, Wei D
Frontiers in oncology 2022;12:890193
Frontiers in oncology 2022;12:890193
Transient Receptor Potential Cation Channel Subfamily V Member 1 Expression Promotes Chemoresistance in Non-Small-Cell Lung Cancer.
Li L, Chen C, Xiang Q, Fan S, Xiao T, Chen Y, Zheng D
Frontiers in oncology 2022;12:773654
Frontiers in oncology 2022;12:773654
Label-free LC-MS/MS proteomics analyses reveal CLIC1 as a predictive biomarker for bladder cancer staging and prognosis.
Wang W, Huang G, Lin H, Ren L, Fu L, Mao X
Frontiers in oncology 2022;12:1102392
Frontiers in oncology 2022;12:1102392
HIF-1/2α-Activated RNF146 Enhances the Proliferation and Glycolysis of Hepatocellular Carcinoma Cells via the PTEN/AKT/mTOR Pathway.
Shen G, Wang H, Zhu N, Lu Q, Liu J, Xu Q, Huang D
Frontiers in cell and developmental biology 2022;10:893888
Frontiers in cell and developmental biology 2022;10:893888
Chicken ISG12(2) attenuates Newcastle disease virus and enhances the efficiency of Newcastle disease vaccine via activating immune pathways.
Liu H, Tian J, Lu K, Li Y, Guan Z, Cao X, Li X, Chang Z, Wang X, Sa X, Yang Z
Transboundary and emerging diseases 2022 Sep;69(5):2634-2648
Transboundary and emerging diseases 2022 Sep;69(5):2634-2648
Nav1.8 in keratinocytes contributes to ROS-mediated inflammation in inflammatory skin diseases.
Zhang Y, Li Y, Zhou L, Yuan X, Wang Y, Deng Q, Deng Z, Xu S, Wang Q, Xie H, Li J
Redox biology 2022 Sep;55:102427
Redox biology 2022 Sep;55:102427
Silica nanoparticle exposure inhibits surfactant protein A and B in A549 cells through ROS-mediated JNK/c-Jun signaling pathway.
Yang X, Yang P, Zhang J, Yang Y, Xiong M, Shi F, Li N, Jin Y
Environmental toxicology 2022 Sep;37(9):2291-2301
Environmental toxicology 2022 Sep;37(9):2291-2301
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Zhu C, Tian M, Liu N, Ma L, Lan X, Yang J, Du J, Ma H, Li Y, Zheng P, Yu J, Peng X
Phytotherapy research : PTR 2022 Sep;36(9):3644-3661
Phytotherapy research : PTR 2022 Sep;36(9):3644-3661
Vagus nerve stimulation promotes the M1-to-M2 transition via inhibition of TLR4/NF-κB in microglial to rescue the reperfusion injury.
Zhang L, Zhang X, Liu Y, Wang S, Jia G
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Sep;31(9):106596
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Sep;31(9):106596
UFL1 alleviates ER stress and apoptosis stimulated by LPS via blocking the ferroptosis pathway in human granulosa-like cells.
Li J, Tang X, Tu X, Jin Z, Dong H, Yang Q, Yao T, Pan Z
Cell stress & chaperones 2022 Sep;27(5):485-497
Cell stress & chaperones 2022 Sep;27(5):485-497
Elevated phosphorylation of EGFR in NSCLC due to mutations in PTPRH.
Swiatnicki MR, Rennhack JP, Ortiz MMO, Hollern DP, Perry AV, Kubiak R, Riveria Riveria SM, O'Reilly S, Andrechek ER
PLoS genetics 2022 Sep;18(9):e1010362
PLoS genetics 2022 Sep;18(9):e1010362
Deficiency of proline/serine-rich coiled-coil protein 1 (PSRC1) accelerates trimethylamine N-oxide-induced atherosclerosis in ApoE(-/-) mice.
Luo T, Liu D, Guo Z, Chen P, Guo Z, Ou C, Chen M
Journal of molecular and cellular cardiology 2022 Sep;170:60-74
Journal of molecular and cellular cardiology 2022 Sep;170:60-74
Phosphorylation of Ser82 on IRF3 acts as negative-feedback regulation of IRF3-dependent innate immunity.
Cheng Q, Yuan L, Guo J, Guo D, Liu X, Li S
The international journal of biochemistry & cell biology 2022 Sep;150:106275
The international journal of biochemistry & cell biology 2022 Sep;150:106275
Gut microbiota-derived metabolites contribute negatively to hindgut barrier function development at the early weaning goat model.
Zhang K, Xu Y, Yang Y, Guo M, Zhang T, Zong B, Huang S, Suo L, Ma B, Wang X, Wu Y, Brugger D, Chen Y
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Sep;10:111-123
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Sep;10:111-123
Metabolic Syndrome Ameliorated by 4-Methylesculetin by Reducing Hepatic Lipid Accumulation.
Li L, Zhu G, Fu G, Zha W, Li H
International journal of molecular sciences 2022 Sep 9;23(18)
International journal of molecular sciences 2022 Sep 9;23(18)
Proteomic and Biochemical Approaches Elucidate the Role of Millimeter-Wave Irradiation in Wheat Growth under Flooding Stress.
Komatsu S, Tsutsui Y, Furuya T, Yamaguchi H, Hitachi K, Tsuchida K, Tani M
International journal of molecular sciences 2022 Sep 8;23(18)
International journal of molecular sciences 2022 Sep 8;23(18)
Acid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis.
Xiao J, Zeng W, Zhang P, Zhou Y, Fang Q
Molecular medicine (Cambridge, Mass.) 2022 Sep 6;28(1):106
Molecular medicine (Cambridge, Mass.) 2022 Sep 6;28(1):106
Supramolecular Hydrogel-Wrapped Gingival Mesenchymal Stem Cells in Cutaneous Radiation Injury.
Nie S, Ren C, Liang X, Cai H, Sun H, Liu F, Ji K, Wang Y, Liu Q
Cells 2022 Sep 30;11(19)
Cells 2022 Sep 30;11(19)
Proteomic characterization of gastric cancer response to chemotherapy and targeted therapy reveals new therapeutic strategies.
Li Y, Xu C, Wang B, Xu F, Ma F, Qu Y, Jiang D, Li K, Feng J, Tian S, Wu X, Wang Y, Liu Y, Qin Z, Liu Y, Qin J, Song Q, Zhang X, Sujie A, Huang J, Liu T, Shen K, Zhao JY, Hou Y, Ding C
Nature communications 2022 Sep 29;13(1):5723
Nature communications 2022 Sep 29;13(1):5723
Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model.
Ji J, Li S, Jiang Z, Yu J, Sun Y, Cai Z, Dong Y, Sun X
International journal of molecular sciences 2022 Sep 16;23(18)
International journal of molecular sciences 2022 Sep 16;23(18)
Role of PARP-1 in Human Cytomegalovirus Infection and Functional Partners Encoded by This Virus.
Zhang W, Guo J, Chen Q
Viruses 2022 Sep 15;14(9)
Viruses 2022 Sep 15;14(9)
MARCH1 promotes the growth and maintaining of stem cell-like characteristics of gastric cancer cells by activating the Wnt/β-catenin signaling pathway.
Liang W, Zhang T, Huo J, Yang J
Tissue & cell 2022 Oct;78:101895
Tissue & cell 2022 Oct;78:101895
LncRNA ALKBH3-AS1 enhances ALKBH3 mRNA stability to promote hepatocellular carcinoma cell proliferation and invasion.
Lu Q, Wang H, Lei X, Ma Q, Zhao J, Sun W, Guo C, Huang D, Xu Q
Journal of cellular and molecular medicine 2022 Oct;26(20):5292-5302
Journal of cellular and molecular medicine 2022 Oct;26(20):5292-5302
Proteome-wide analysis of the hippocampus in adolescent male mice with learning and memory impairment caused by chronic ethanol exposure.
Liu D, Liu S, Li J, Liu X, Wu X, Peng Y, Shen Q
Neurobiology of learning and memory 2022 Oct;194:107661
Neurobiology of learning and memory 2022 Oct;194:107661
The phytochemical constituents and protective effect of Fritillaria hupehensis on acute lung injury.
Xiang ML, Zhao YL, Liu YY, Yan XJ, Chen S, Luo XD
Fitoterapia 2022 Oct;162:105283
Fitoterapia 2022 Oct;162:105283
Reticulocalbin3: A Ca(2+) homeostasis regulator that promotes esophageal squamous cell carcinoma progression and cisplatin resistance.
Cai R, Wang P, Zhao X, Lu X, Deng R, Wang X, Hong C, Lin J
Cancer science 2022 Oct;113(10):3593-3607
Cancer science 2022 Oct;113(10):3593-3607
Targeting PERK mediated endoplasmic reticulum stress attenuates neuroinflammation and alleviates lipopolysaccharide-induced depressive-like behavior in male mice.
Xu XF, Shi MM, Luo MY, Liu DD, Guo DM, Ling C, Zhong XL, Xu Y, Cao WY
International immunopharmacology 2022 Oct;111:109092
International immunopharmacology 2022 Oct;111:109092
Local Application of Krill Oil Accelerates the Healing of Artificially Created Wounds in Diabetic Mice.
Hao W, Meng H, Li H, Zheng Y, Song C, Jiang Z, Bai X, Zhang Z, Du L, Liu P, Wu H
Nutrients 2022 Oct 5;14(19)
Nutrients 2022 Oct 5;14(19)
Hepatic inactivation of murine Surf4 results in marked reduction in plasma cholesterol.
Tang VT, McCormick J, Xu B, Wang Y, Fang H, Wang X, Siemieniak D, Khoriaty R, Emmer BT, Chen XW, Ginsburg D
eLife 2022 Oct 4;11
eLife 2022 Oct 4;11
Z. morio Hemolymph Relieves E. coli-Induced Mastitis by Inhibiting Inflammatory Response and Repairing the Blood-Milk Barrier.
Zou Y, Wang X, Xu J, Wang S, Li S, Zhu Y, Wang J
International journal of molecular sciences 2022 Oct 31;23(21)
International journal of molecular sciences 2022 Oct 31;23(21)
Knockdown of CLAUDIN-6 Inhibited Apoptosis and Induced Proliferation of Bovine Cumulus Cells.
Wang W, Zou H, Chen N, Tian Y, Hao H, Pang Y, Zhao X, Zhu H, Yu D, Du W
International journal of molecular sciences 2022 Oct 30;23(21)
International journal of molecular sciences 2022 Oct 30;23(21)
Hypoxia-Regulated lncRNA USP2-AS1 Drives Head and Neck Squamous Cell Carcinoma Progression.
Tang J, Wu Z, Wang X, Hou Y, Bai Y, Tian Y
Cells 2022 Oct 28;11(21)
Cells 2022 Oct 28;11(21)
Angiotensin-converting enzyme 2 identifies immuno-hot tumors suggesting angiotensin-(1-7) as a sensitizer for chemotherapy and immunotherapy in breast cancer.
Mei J, Cai Y, Xu R, Yu X, Han X, Weng M, Chen L, Ma T, Gao T, Gao F, Xia T, Zhu Y, Zhang Y
Biological procedures online 2022 Oct 25;24(1):15
Biological procedures online 2022 Oct 25;24(1):15
Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis.
Deng R, Lu X, Hong C, Cai R, Wang P, Xiong L, Wang X, Chen Q, Lin J
Journal of translational medicine 2022 Oct 23;20(1):485
Journal of translational medicine 2022 Oct 23;20(1):485
TRPM8 contributes to sex dimorphism by promoting recovery of normal sensitivity in a mouse model of chronic migraine.
Alarcón-Alarcón D, Cabañero D, de Andrés-López J, Nikolaeva-Koleva M, Giorgi S, Fernández-Ballester G, Fernández-Carvajal A, Ferrer-Montiel A
Nature communications 2022 Oct 22;13(1):6304
Nature communications 2022 Oct 22;13(1):6304
The role of E3 ubiquitin ligase WWP2 and the regulation of PARP1 by ubiquitinated degradation in acute lymphoblastic leukemia.
Lu X, Huang X, Xu H, Lu S, You S, Xu J, Zhan Q, Dong C, Zhang N, Zhang Y, Cao L, Zhang X, Zhang N, Zhang L
Cell death discovery 2022 Oct 18;8(1):421
Cell death discovery 2022 Oct 18;8(1):421
Kaempferol prevents angiogenesis of rat intestinal microvascular endothelial cells induced by LPS and TNF-α via inhibiting VEGF/Akt/p38 signaling pathways and maintaining gut-vascular barrier integrity.
Yu R, Zhong J, Zhou Q, Ren W, Liu Z, Bian Y
Chemico-biological interactions 2022 Oct 1;366:110135
Chemico-biological interactions 2022 Oct 1;366:110135
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
Liu F, Wang Y, Chen L, Bello BK, Zhang T, Yang H, Li X, Pan E, Feng H, Dong J
Ecotoxicology and environmental safety 2022 Oct 1;244:114081
Ecotoxicology and environmental safety 2022 Oct 1;244:114081
Synthetic Retinoid Kills Drug-Resistant Cancer Stem Cells via Inducing RARγ-Translocation-Mediated Tension Reduction and Chromatin Decondensation.
Zhang Y, Dong Q, An Q, Zhang C, Mohagheghian E, Niu B, Qi F, Wei F, Chen S, Chen X, Wang A, Cao X, Wang N, Chen J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Nov;9(31):e2203173
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Nov;9(31):e2203173
Knockdown of TTC9 inhibits the proliferation, migration and invasion, but induces the apoptosis of lung adenocarcinoma cells.
Huang X, Jiang L, Wen Z, Yuan M, Zhong Y
Heliyon 2022 Nov;8(11):e11254
Heliyon 2022 Nov;8(11):e11254
Overexpression of PYGO1 promotes early cardiac lineage development in human umbilical cord mesenchymal stromal/stem cells by activating the Wnt/β-catenin pathway.
Shen J, Wu X, Zhu P, Zhuang J, Qin B, Sun F, Yuan W, Fan X, Jiang Z, Li F, Li Y, Wang Y, Zhao M
Human cell 2022 Nov;35(6):1722-1735
Human cell 2022 Nov;35(6):1722-1735
Homozygous missense mutation in CCDC155 disrupts the transmembrane distribution of CCDC155 and SUN1, resulting in non-obstructive azoospermia and premature ovarian insufficiency in humans.
Wu H, Zhang X, Hua R, Li Y, Cheng L, Li K, Liu Y, Gao Y, Shen Q, Wang G, Lv M, Xu Y, He X, Cao Y, Liu M
Human genetics 2022 Nov;141(11):1795-1809
Human genetics 2022 Nov;141(11):1795-1809
Hydrogen improves exercise endurance in rats by promoting mitochondrial biogenesis.
Luo M, Lu J, Li C, Wen B, Chu W, Dang X, Zhang Y, An G, Wang J, Fan R, Chen X
Genomics 2022 Nov;114(6):110523
Genomics 2022 Nov;114(6):110523
Hyperglycemia promotes myocardial dysfunction via the ERS-MAPK10 signaling pathway in db/db mice.
Deng YW, Liu F, Li ZT, Gao JH, Zhao Y, Yang XL, Xia YL
Laboratory investigation; a journal of technical methods and pathology 2022 Nov;102(11):1192-1202
Laboratory investigation; a journal of technical methods and pathology 2022 Nov;102(11):1192-1202
Regulation of cohesin-mediated chromosome folding by PDS5 in mammals.
Yu D, Chen G, Wang Y, Wang Y, Lin R, Liu N, Zhu P, Liu H, Hu T, Feng R, Feng H, Lan F, Cai J, Chen H
EMBO reports 2022 Nov 7;23(11):e54853
EMBO reports 2022 Nov 7;23(11):e54853
Discovery of a novel Pleuromutilin derivative as anti-IPF lead compound via high-throughput assay.
Zhang K, Liang J, Wang N, Li N, Jiang Y, Li X, Yang C, Zhou H, Yang G
European journal of medicinal chemistry 2022 Nov 5;241:114643
European journal of medicinal chemistry 2022 Nov 5;241:114643
Functional Attenuation of UCP1 as the Potential Mechanism for a Thickened Blubber Layer in Cetaceans.
Zhou M, Wu T, Chen Y, Xu S, Yang G
Molecular biology and evolution 2022 Nov 3;39(11)
Molecular biology and evolution 2022 Nov 3;39(11)
Trichostatin D as a Novel KLF2 Activator Attenuates TNFα-Induced Endothelial Inflammation.
Lei L, Chen M, Wang C, Jiang X, Li Y, Wang W, Li S, Zhao L, Sheng R, Han J, Zhang Y, Chen Y, Yan B, Wu Y, Yu L, Si S, Xu Y
International journal of molecular sciences 2022 Nov 3;23(21)
International journal of molecular sciences 2022 Nov 3;23(21)
Differential requirements of IQUB for the assembly of radial spoke 1 and the motility of mouse cilia and flagella.
Zhang X, Xiao Z, Zhang J, Xu C, Liu S, Cheng L, Zhou S, Zhao S, Zhang Y, Wu J, Wang Y, Liu M
Cell reports 2022 Nov 22;41(8):111683
Cell reports 2022 Nov 22;41(8):111683
Hydrogen Sulfide Regulates SERCA2a Ubiquitylation via Muscle RING Finger-1 S-Sulfhydration to Affect Cardiac Contractility in db/db Mice.
Peng S, Zhao D, Li Q, Wang M, Zhang S, Pang K, Huang J, Lu F, Chen H, Zhang W
Cells 2022 Nov 2;11(21)
Cells 2022 Nov 2;11(21)
mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters.
Liu Y, Azizian NG, Sullivan DK, Li Y
Nature communications 2022 Nov 17;13(1):7047
Nature communications 2022 Nov 17;13(1):7047
NAP1L5 targeting combined with MYH9 Inhibit HCC progression through PI3K/AKT/mTOR signaling pathway.
Zhao R, Ge Y, Gong Y, Li B, Xiao B, Zuo S
Aging 2022 Nov 11;14(22):9000-9019
Aging 2022 Nov 11;14(22):9000-9019
Inhibitory effect of tanshinone IIA, resveratrol and silibinin on enterovirus 68 production through inhibiting ATM and DNA-PK pathway.
Su Y, Wu T, Yu XY, Huo WB, Wang SH, Huan C, Liu YM, Liu JM, Cui MN, Li XH, Yu JH
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153977
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153977
cGAS-STING mediates cytoplasmic mitochondrial-DNA-induced inflammatory signal transduction during accelerated senescence of pancreatic β-cells induced by metabolic stress.
Hu H, Zhao R, He Q, Cui C, Song J, Guo X, Zang N, Yang M, Zou Y, Yang J, Li J, Wang L, Xia L, Wang L, He F, Hou X, Yan F, Chen L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 May;36(5):e22266
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 May;36(5):e22266
SMAD4 Inhibits Granulosa Cell Apoptosis via the miR-183-96-182 Cluster and FoxO1 Axis.
Yao W, Wang S, Du X, Lin C, Zhang J, Pan Z, Li Q
Reproductive sciences (Thousand Oaks, Calif.) 2022 May;29(5):1577-1585
Reproductive sciences (Thousand Oaks, Calif.) 2022 May;29(5):1577-1585
Type IIB PKA is highly expressed in β cells and controls cell proliferation via regulating Cyclin D1 expression.
Jiang Y, Zhu L, Wu D, Ni Y, Huang C, Ye H, Yang Y, Liu R, Li Y
The FEBS journal 2022 May;289(10):2865-2876
The FEBS journal 2022 May;289(10):2865-2876
The roles of grouper TAK1 in regulating the infection of Singapore grouper iridovirus.
Zhang L, Kang S, Chen H, Liao J, Sun M, Wu S, Xu Z, Xu L, Zhang X, Qin Q, Wei J
Fish & shellfish immunology 2022 May;124:164-173
Fish & shellfish immunology 2022 May;124:164-173
Ubiquitin-like modifier 1 ligating enzyme 1 relieves cisplatin-induced premature ovarian failure by reducing endoplasmic reticulum stress in granulosa cells.
Tang X, Dong H, Fang Z, Li J, Yang Q, Yao T, Pan Z
Reproductive biology and endocrinology : RB&E 2022 May 24;20(1):84
Reproductive biology and endocrinology : RB&E 2022 May 24;20(1):84
MiR-135a-5p suppresses trophoblast proliferative, migratory, invasive, and angiogenic activity in the context of unexplained spontaneous abortion.
Lu Y, Zhang X, Li X, Deng L, Wei C, Yang D, Tan X, Pan W, Pang L
Reproductive biology and endocrinology : RB&E 2022 May 24;20(1):82
Reproductive biology and endocrinology : RB&E 2022 May 24;20(1):82
Aberrant translation regulated by METTL1/WDR4-mediated tRNA N7-methylguanosine modification drives head and neck squamous cell carcinoma progression.
Chen J, Li K, Chen J, Wang X, Ling R, Cheng M, Chen Z, Chen F, He Q, Li S, Zhang C, Jiang Y, Chen Q, Wang A, Chen D
Cancer communications (London, England) 2022 Mar;42(3):223-244
Cancer communications (London, England) 2022 Mar;42(3):223-244
Ubiquitylation of cyclin C by HACE1 regulates cisplatin-associated sensitivity in gastric cancer.
Jiang HY, Chen YL, Xu XX, Li CY, Chen Y, Li DP, Zeng XQ, Gao H
Clinical and translational medicine 2022 Mar;12(3):e770
Clinical and translational medicine 2022 Mar;12(3):e770
Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury.
Lin F, Chen W, Zhou J, Zhu J, Yao Q, Feng B, Feng X, Shi X, Pan Q, Yu J, Li L, Cao H
Cell death & disease 2022 Mar 26;13(3):271
Cell death & disease 2022 Mar 26;13(3):271
p62 Promotes the Mitochondrial Localization of p53 through Its UBA Domain and Participates in Regulating the Sensitivity of Ovarian Cancer Cells to Cisplatin.
Kong Q, Yan X, Cheng M, Jiang X, Xu L, Shen L, Yu H, Sun L
International journal of molecular sciences 2022 Mar 18;23(6)
International journal of molecular sciences 2022 Mar 18;23(6)
Iron metabolism protein transferrin receptor 1 involves in cervical cancer progression by affecting gene expression and alternative splicing in HeLa cells.
Huang N, Wei Y, Cheng Y, Wang X, Wang Q, Chen D, Li W
Genes & genomics 2022 Jun;44(6):637-650
Genes & genomics 2022 Jun;44(6):637-650
Effects of ALA-PDT on the macrophages in wound healing and its related mechanisms in vivo and in vitro.
Li L, Yang Y, Yang Z, Zheng M, Luo G, He W, Yin R
Photodiagnosis and photodynamic therapy 2022 Jun;38:102816
Photodiagnosis and photodynamic therapy 2022 Jun;38:102816
Rutin-activated adipose tissue thermogenesis is correlated with increased intestinal short-chain fatty acid levels.
Cheng L, Shi L, He C, Wang C, Lv Y, Li H, An Y, Dai H, Duan Y, Zhang H, Huang Y, Fu W, Meng Y, Zhao B
Phytotherapy research : PTR 2022 Jun;36(6):2495-2510
Phytotherapy research : PTR 2022 Jun;36(6):2495-2510
Dexmedetomidine attenuates perioperative neurocognitive disorders by suppressing hippocampal neuroinflammation and HMGB1/RAGE/NF-κB signaling pathway.
Wang J, Xin Y, Chu T, Liu C, Xu A
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113006
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:113006
NPM1 promotes cell proliferation by targeting PRDX6 in colorectal cancer.
Wang D, Li Y, Liu Y, Cheng S, Liu F, Zuo R, Ding C, Shi S, Liu G
The international journal of biochemistry & cell biology 2022 Jun;147:106233
The international journal of biochemistry & cell biology 2022 Jun;147:106233
Deacetylation of Caveolin-1 by Sirt6 induces autophagy and retards high glucose-stimulated LDL transcytosis and atherosclerosis formation.
Zhao Y, Jia X, Yang X, Bai X, Lu Y, Zhu L, Cheng W, Shu M, Zhu Y, Du X, Wang L, Shu Y, Song Y, Jin S
Metabolism: clinical and experimental 2022 Jun;131:155162
Metabolism: clinical and experimental 2022 Jun;131:155162
Heart-targeted amelioration of sepsis-induced myocardial dysfunction by microenvironment responsive nitric oxide nanogenerators in situ.
Ouyang M, Ouyang X, Peng Z, Liu M, Xu G, Zou Z, Zhang M, Shang Q
Journal of nanobiotechnology 2022 Jun 7;20(1):263
Journal of nanobiotechnology 2022 Jun 7;20(1):263
Sesamin Activates Skeletal Muscle FNDC5 Expression and Increases Irisin Secretion via the SIRT1 Signaling Pathway.
Kou G, Li P, Shi Y, Traore SS, Shi X, Amoah AN, Cui Z, Lyu Q
Journal of agricultural and food chemistry 2022 Jun 29;70(25):7704-7715
Journal of agricultural and food chemistry 2022 Jun 29;70(25):7704-7715
The mechanism of dioscin preventing lung cancer based on network pharmacology and experimental validation.
Xi P, Niu Y, Zhang Y, Li W, Gao F, Gu W, Kui F, Liu Z, Lu L, Du G
Journal of ethnopharmacology 2022 Jun 28;292:115138
Journal of ethnopharmacology 2022 Jun 28;292:115138
circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop.
Li X, Wang J, Lin W, Yuan Q, Lu Y, Wang H, Chen Y, Chen L, Dai P, Long H, Li X
Molecular cancer 2022 Jun 23;21(1):135
Molecular cancer 2022 Jun 23;21(1):135
Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached.
Wilcock DJ, Badrock AP, Wong CW, Owen R, Guerin M, Southam AD, Johnston H, Telfer BA, Fullwood P, Watson J, Ferguson H, Ferguson J, Lloyd GR, Jankevics A, Dunn WB, Wellbrock C, Lorigan P, Ceol C, Francavilla C, Smith MP, Hurlstone AFL
Cell reports 2022 Jun 21;39(12):110995
Cell reports 2022 Jun 21;39(12):110995
Transcriptome study digs out BMP2 involved in adipogenesis in sheep tails.
Jin M, Fei X, Li T, Lu Z, Chu M, Di R, He X, Wang X, Wei C
BMC genomics 2022 Jun 21;23(1):457
BMC genomics 2022 Jun 21;23(1):457
JNK and Jag1/Notch2 co-regulate CXCL16 to facilitate cypermethrin-induced kidney damage.
Liu C, Wu M, Qu J, Huang X, Zeng Q, Ha M
Ecotoxicology and environmental safety 2022 Jun 15;238:113582
Ecotoxicology and environmental safety 2022 Jun 15;238:113582
Difenoconazole causes spleen tissue damage and immune dysfunction of carp through oxidative stress and apoptosis.
Liu F, Li X, Bello BK, Zhang T, Yang H, Wang K, Dong J
Ecotoxicology and environmental safety 2022 Jun 1;237:113563
Ecotoxicology and environmental safety 2022 Jun 1;237:113563
Chronic exposure of alcohol triggers microglia-mediated synaptic elimination inducing cognitive impairment.
Lan L, Wang H, Zhang X, Shen Q, Li X, He L, Rong X, Peng J, Mo J, Peng Y
Experimental neurology 2022 Jul;353:114061
Experimental neurology 2022 Jul;353:114061
Lysyl oxidase-like 2 inhibitor rescues D-galactose-induced skeletal muscle fibrosis.
Wu Y, Wu Y, Yang Y, Yu J, Wu J, Liao Z, Guo A, Sun Y, Zhao Y, Chen J, Xiao Q
Aging cell 2022 Jul;21(7):e13659
Aging cell 2022 Jul;21(7):e13659
The neuroprotective effects of GPR55 against hippocampal neuroinflammation and impaired adult neurogenesis in CSDS mice.
Shen SY, Yu R, Li W, Liang LF, Han QQ, Huang HJ, Li B, Xu SF, Wu GC, Zhang YQ, Yu J
Neurobiology of disease 2022 Jul;169:105743
Neurobiology of disease 2022 Jul;169:105743
Time series RNA-seq analysis identifies MAPK10 as a critical gene in diabetes mellitus-induced atrial fibrillation in mice.
Liu F, Deng Y, Zhao Y, Li Z, Gao J, Zhang Y, Yang X, Liu Y, Xia Y
Journal of molecular and cellular cardiology 2022 Jul;168:70-82
Journal of molecular and cellular cardiology 2022 Jul;168:70-82
Cortistatin attenuates titanium particle-induced osteolysis through regulation of TNFR1-ROS-caspase-3 signaling in osteoblasts.
Cao J, Ma X, Liu L, Zhang G, Wu Y, Fu Y, Gong A, Yang Z, Zhao Y, Zhang L, Li Y
Annals of the New York Academy of Sciences 2022 Jul;1513(1):140-152
Annals of the New York Academy of Sciences 2022 Jul;1513(1):140-152
Morphological and Proteomic Analyses of Soybean Seedling Interaction Mechanism Affected by Fiber Crosslinked with Zinc-Oxide Nanoparticles.
Komatsu S, Murata K, Yakeishi S, Shimada K, Yamaguchi H, Hitachi K, Tsuchida K, Obi R, Akita S, Fukuda R
International journal of molecular sciences 2022 Jul 3;23(13)
International journal of molecular sciences 2022 Jul 3;23(13)
Discovery of Novel Phosphoinositide-3-Kinase α Inhibitors with High Selectivity, Excellent Bioavailability, and Long-Acting Efficacy for Gastric Cancer.
Hou Y, Zhang F, Min W, Yuan K, Kuang W, Wang X, Zhu Y, Sun C, Xia F, Wang Y, Zhang H, Wang L, Yang P
Journal of medicinal chemistry 2022 Jul 28;65(14):9873-9892
Journal of medicinal chemistry 2022 Jul 28;65(14):9873-9892
Dysregulation of SIRT3 SUMOylation Confers AML Chemoresistance via Controlling HES1-Dependent Fatty Acid Oxidation.
Zhang Y, Shen Y, Wei W, Wang W, Jiang D, Ren Y, Peng Z, Fan Q, Cheng J, Ma J
International journal of molecular sciences 2022 Jul 27;23(15)
International journal of molecular sciences 2022 Jul 27;23(15)
Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage.
Zhou H, Shen X, Yan C, Xiong W, Ma Z, Tan Z, Wang J, Li Y, Liu J, Duan A, Liu F
Stem cell research & therapy 2022 Jul 16;13(1):322
Stem cell research & therapy 2022 Jul 16;13(1):322
Quantitative proteomics analysis to assess protein expression levels in the ovaries of pubescent goats.
Qin P, Ye J, Gong X, Yan X, Lin M, Lin T, Liu T, Li H, Wang X, Zhu Y, Li X, Liu Y, Li Y, Ling Y, Zhang X, Fang F
BMC genomics 2022 Jul 13;23(1):507
BMC genomics 2022 Jul 13;23(1):507
Increased m6A-RNA methylation and FTO suppression is associated with myocardial inflammation and dysfunction during endotoxemia in mice.
Dubey PK, Patil M, Singh S, Dubey S, Ahuja P, Verma SK, Krishnamurthy P
Molecular and cellular biochemistry 2022 Jan;477(1):129-141
Molecular and cellular biochemistry 2022 Jan;477(1):129-141
BCAA-BCKA axis regulates WAT browning through acetylation of PRDM16.
Ma QX, Zhu WY, Lu XC, Jiang D, Xu F, Li JT, Zhang L, Wu YL, Chen ZJ, Yin M, Huang HY, Lei QY
Nature metabolism 2022 Jan;4(1):106-122
Nature metabolism 2022 Jan;4(1):106-122
Bioglass promotes wound healing by inhibiting endothelial cell pyroptosis through regulation of the connexin 43/reactive oxygen species (ROS) signaling pathway.
Zhang K, Chai B, Ji H, Chen L, Ma Y, Zhu L, Xu J, Wu Y, Lan Y, Li H, Feng Z, Xiao J, Zhang H, Xu K
Laboratory investigation; a journal of technical methods and pathology 2022 Jan;102(1):90-101
Laboratory investigation; a journal of technical methods and pathology 2022 Jan;102(1):90-101
A homozygous loss-of-function mutation in FBXO43 causes human non-obstructive azoospermia.
Wu H, Zhang X, Shen Q, Liu Y, Gao Y, Wang G, Lv M, Hua R, Xu Y, Zhou P, Wei Z, Tao F, He X, Cao Y, Liu M
Clinical genetics 2022 Jan;101(1):55-64
Clinical genetics 2022 Jan;101(1):55-64
CHMFL-BMX-078, a BMX inhibitor, overcomes the resistance of melanoma to vemurafenib via inhibiting AKT pathway.
Jiang S, Jiang T, Huang H, Chen X, Li L, Wang Z, Fei J, Liu C, Liu Z, Cheng Y
Chemico-biological interactions 2022 Jan 5;351:109747
Chemico-biological interactions 2022 Jan 5;351:109747
An efficient strategy for digging protein-protein interactions for rational drug design - A case study with HIF-1α/VHL.
Xue X, Kang JB, Yang X, Li N, Chang L, Ji J, Meng XK, Zhang HQ, Zhong Y, Yu SP, Wu WY, Wang XL, Li NG, Sun SL
European journal of medicinal chemistry 2022 Jan 5;227:113871
European journal of medicinal chemistry 2022 Jan 5;227:113871
Qingwei San treats oral ulcer subjected to stomach heat syndrome in db/db mice by targeting TLR4/MyD88/NF-κB pathway.
Shi L, An Y, Cheng L, Li Y, Li H, Wang C, Lv Y, Duan Y, Dai H, He C, Zhang H, Huang Y, Fu W, Wang S, Zhao B, Wang Y, Zhao Y
Chinese medicine 2022 Jan 4;17(1):1
Chinese medicine 2022 Jan 4;17(1):1
ID2 inhibits innate antiviral immunity by blocking TBK1- and IKKε-induced activation of IRF3.
Yu C, Wang B, Zhu Y, Zhang C, Ren L, Lei X, Xiang Z, Zhou Z, Huang H, Wang J, Zhao Z
Science signaling 2022 Jan 4;15(715):eabh0068
Science signaling 2022 Jan 4;15(715):eabh0068
Increased expression of osteopontin in subchondral bone promotes bone turnover and remodeling, and accelerates the progression of OA in a mouse model.
Lin C, Chen Z, Guo D, Zhou L, Lin S, Li C, Li S, Wang X, Lin B, Ding Y
Aging 2022 Jan 4;14(1):253-271
Aging 2022 Jan 4;14(1):253-271
The bibenzyl derivatives of Dendrobium officinale prevent UV-B irradiation induced photoaging via SIRT3.
Chen DK, Shao HY, Yang L, Hu JM
Natural products and bioprospecting 2022 Jan 27;12(1):1
Natural products and bioprospecting 2022 Jan 27;12(1):1
Sodium hydrosulfide reverses β(2)-microglobulin-induced depressive-like behaviors of male Sprague-Dawley rats: Involving improvement of synaptic plasticity and enhancement of Warburg effect in hippocampus.
Yang SQ, Tang YY, Zeng D, Tian Q, Wei HJ, Wang CY, Zhang P, Chen YJ, Zou W, Tang XQ
Behavioural brain research 2022 Jan 24;417:113562
Behavioural brain research 2022 Jan 24;417:113562
Nrf2 loss of function exacerbates endoplasmic reticulum stress-induced apoptosis in TBI mice.
Sun G, Zhao Z, Lang J, Sun B, Zhao Q
Neuroscience letters 2022 Jan 23;770:136400
Neuroscience letters 2022 Jan 23;770:136400
Krill Oil Inhibits NLRP3 Inflammasome Activation in the Prevention of the Pathological Injuries of Diabetic Cardiomyopathy.
Sun X, Sun X, Meng H, Wu J, Guo X, Du L, Wu H
Nutrients 2022 Jan 15;14(2)
Nutrients 2022 Jan 15;14(2)
Amelioration of scopolamine-induced learning and memory impairment by the TRPV4 inhibitor HC067047 in ICR mice.
Deng Y, Li W, Niu L, Luo X, Li J, Zhang Y, Liu H, He J, Wan W
Neuroscience letters 2022 Jan 10;767:136209
Neuroscience letters 2022 Jan 10;767:136209
DsbA-L interacts with VDAC1 in mitochondrion-mediated tubular cell apoptosis and contributes to the progression of acute kidney disease.
Li X, Pan J, Li H, Li G, Liu B, Tang X, Liu X, He Z, Peng Z, Zhang H, Wang L, Li Y, Xiang X, Chai X, Yuan Y, Zheng P, Zhang D
EBioMedicine 2022 Feb;76:103859
EBioMedicine 2022 Feb;76:103859
Supervillin Contributes to LPS-induced Inflammatory Response in THP-1 Cell-derived Macrophages.
Zhou J, Que Y, Pan L, Li X, Zhu C, Jin L, Li S
Inflammation 2022 Feb;45(1):356-371
Inflammation 2022 Feb;45(1):356-371
Chronic exposure to biomass ambient particulate matter triggers alveolar macrophage polarization and activation in the rat lung.
Wang S, Chen Y, Hong W, Li B, Zhou Y, Ran P
Journal of cellular and molecular medicine 2022 Feb;26(4):1156-1168
Journal of cellular and molecular medicine 2022 Feb;26(4):1156-1168
Dual effects of bisphenol A on wound healing, involvement of estrogen receptor β.
Wen X, Zhu M, Li Z, Li T, Xu X
Ecotoxicology and environmental safety 2022 Feb;231:113207
Ecotoxicology and environmental safety 2022 Feb;231:113207
KDM2B overexpression prevents myocardial ischemia-reperfusion injury in rats through regulating inflammatory response via the TLR4/NF-κB p65 axis.
Wei Z, Luo L, Hu S, Tian R, Liu Z
Experimental and therapeutic medicine 2022 Feb;23(2):154
Experimental and therapeutic medicine 2022 Feb;23(2):154
MxB inhibits long interspersed element type 1 retrotransposition.
Huang Y, Xu F, Mei S, Liu X, Zhao F, Wei L, Fan Z, Hu Y, Wang L, Ai B, Cen S, Liang C, Guo F
PLoS genetics 2022 Feb;18(2):e1010034
PLoS genetics 2022 Feb;18(2):e1010034
Resveratrol attenuates inflammation and apoptosis through alleviating endoplasmic reticulum stress via Akt/mTOR pathway in fungus-induced allergic airways inflammation.
Wang S, Gong L, Mo Y, Zhang J, Jiang Z, Tian Z, Shao C
International immunopharmacology 2022 Feb;103:108489
International immunopharmacology 2022 Feb;103:108489
Vagus nerve stimulation alleviated cerebral ischemia and reperfusion injury in rats by inhibiting pyroptosis via α7 nicotinic acetylcholine receptor.
Tang H, Li J, Zhou Q, Li S, Xie C, Niu L, Ma J, Li C
Cell death discovery 2022 Feb 8;8(1):54
Cell death discovery 2022 Feb 8;8(1):54
Toddalolactone protects against osteoarthritis by ameliorating chondrocyte inflammation and suppressing osteoclastogenesis.
Xu Y, Xue S, Zhang T, Jin X, Wang C, Lu H, Zhong Y, Chen H, Zhu L, Ma J, Sang W
Chinese medicine 2022 Feb 5;17(1):18
Chinese medicine 2022 Feb 5;17(1):18
RFC2: a prognosis biomarker correlated with the immune signature in diffuse lower-grade gliomas.
Zhao X, Wang Y, Li J, Qu F, Fu X, Liu S, Wang X, Xie Y, Zhang X
Scientific reports 2022 Feb 24;12(1):3122
Scientific reports 2022 Feb 24;12(1):3122
The expression of m6A enzymes in the hippocampus of diabetic cognitive impairment mice and the possible improvement of YTHDF1.
Li M, Zhong X, Zhao Z, Zeng Z, Yuan Q, Xiao X, Zu X, Liu J
Brain research 2022 Feb 15;1777:147766
Brain research 2022 Feb 15;1777:147766
Inhibition of base editors with anti-deaminases derived from viruses.
Liu Z, Chen S, Lai L, Li Z
Nature communications 2022 Feb 1;13(1):597
Nature communications 2022 Feb 1;13(1):597
FAEE exerts a protective effect against osteoporosis by regulating the MAPK signalling pathway.
Wang MY, An MF, Fan MS, Zhang SS, Sun ZR, Zhao YL, Xiang ZM, Sheng J
Pharmaceutical biology 2022 Dec;60(1):467-478
Pharmaceutical biology 2022 Dec;60(1):467-478
Cdk5 Promotes Mitochondrial Fission via Drp1 Phosphorylation at S616 in Chronic Ethanol Exposure-Induced Cognitive Impairment.
Liu D, Li J, Rong X, Li J, Peng Y, Shen Q
Molecular neurobiology 2022 Dec;59(12):7075-7094
Molecular neurobiology 2022 Dec;59(12):7075-7094
Cellular communication network factor 1 interlinks autophagy and ERK signaling to promote osteogenesis of periodontal ligament stem cells.
Li Z, Wu Z, Xi X, Zhao F, Liu H, Liu D
Journal of periodontal research 2022 Dec;57(6):1169-1182
Journal of periodontal research 2022 Dec;57(6):1169-1182
The protective effects of Xuebijing injection on intestinal injuries of mice exposed to irradiation.
Dong Y, Zhang Y, Wang X, Li W, Zhang J, Lu L, Dong H, Fan S, Meng A, Li D
Animal models and experimental medicine 2022 Dec;5(6):565-574
Animal models and experimental medicine 2022 Dec;5(6):565-574
Defective autophagy triggered by arterial cyclic stretch promotes neointimal hyperplasia in vein grafts via the p62/nrf2/slc7a11 signaling pathway.
Chen Y, Bao M, Liu JT, Bao H, Zhang SM, Lou Y, Qi YX
Journal of molecular and cellular cardiology 2022 Dec;173:101-114
Journal of molecular and cellular cardiology 2022 Dec;173:101-114
Attachment of -tBu groups to aza-BODIPY core at 3,5-sites with ultra-large Stokes shift to enhance photothermal therapy through apoptosis mechanism.
Li R, Ren J, Zhang D, Lv M, Wang Z, Wang H, Zhang S, Du J, Jiang XD, Wang G
Materials today. Bio 2022 Dec;16:100446
Materials today. Bio 2022 Dec;16:100446
PVT1/miR-145-5p/HK2 modulates vascular smooth muscle cells phenotype switch via glycolysis: The new perspective on the spiral artery remodeling.
Wu M, Liu W, Huang H, Chen Z, Chen Y, Zhong Y, Jin Z, Liu X, Zou L
Placenta 2022 Dec;130:25-33
Placenta 2022 Dec;130:25-33
mmu-lncRNA 121686/hsa-lncRNA 520657 induced by METTL3 drive the progression of AKI by targeting miR-328-5p/HtrA3 signaling axis.
Pan J, Xie Y, Li H, Li X, Chen J, Liu X, Zhou J, Tang X, He Z, Peng Z, Zhang H, Li Y, Xiang X, Yuan Y, Zhang D
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Dec 7;30(12):3694-3713
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Dec 7;30(12):3694-3713
Proteomic-Based Approach Reveals the Involvement of Apolipoprotein A-I in Related Phenotypes of Autism Spectrum Disorder in the BTBR Mouse Model.
Li Q, Shi Y, Li X, Yang Y, Zhang X, Xu L, Ma Z, Wang J, Fan L, Wu L
International journal of molecular sciences 2022 Dec 4;23(23)
International journal of molecular sciences 2022 Dec 4;23(23)
RNA-m6A modification of HDGF mediated by Mettl3 aggravates the progression of atherosclerosis by regulating macrophages polarization via energy metabolism reprogramming.
Zheng L, Chen X, Yin Q, Gu J, Chen J, Chen M, Zhang Y, Dong M, Jiang H, Yin N, Chen H, Li X
Biochemical and biophysical research communications 2022 Dec 20;635:120-127
Biochemical and biophysical research communications 2022 Dec 20;635:120-127
Effect of miR-143-3p from Extracellular Vesicles of Porcine Uterine Luminal Fluid on Porcine Trophoblast Cells.
Ding Y, Hu Q, Gan J, Zang X, Gu T, Wu Z, Cai G, Hong L
Animals : an open access journal from MDPI 2022 Dec 2;12(23)
Animals : an open access journal from MDPI 2022 Dec 2;12(23)
Melatonin protects oocytes from cadmium exposure-induced meiosis defects by changing epigenetic modification and enhancing mitochondrial morphology in the mouse.
Qu J, Wang Q, Niu H, Sun X, Ji D, Li Y
Ecotoxicology and environmental safety 2022 Dec 15;248:114311
Ecotoxicology and environmental safety 2022 Dec 15;248:114311
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
Zhou X, Zhang X, Zhou X, Abulimiti G, Wang Y, Zhang Q, Cong R, Ji C, Luan J, Yao L, Yang J, Song N
Ecotoxicology and environmental safety 2022 Dec 1;247:114241
Ecotoxicology and environmental safety 2022 Dec 1;247:114241
A synthetic pregnenolone analog promotes microtubule dynamics and neural development.
Kolas V, Bandonil JSA, Wali N, Hsia KC, Shie JJ, Chung BC
Cell & bioscience 2022 Dec 1;12(1):190
Cell & bioscience 2022 Dec 1;12(1):190
Hypoxia facilitates proliferation of smooth muscle cells derived from pluripotent stem cells for vascular tissue engineering.
Fang L, Mei J, Yao B, Liu J, Liu P, Wang X, Zhou J, Lin Z
Journal of tissue engineering and regenerative medicine 2022 Aug;16(8):744-756
Journal of tissue engineering and regenerative medicine 2022 Aug;16(8):744-756
ROS-responsive polymer nanoparticles with enhanced loading of dexamethasone effectively modulate the lung injury microenvironment.
Muhammad W, Zhu J, Zhai Z, Xie J, Zhou J, Feng X, Feng B, Pan Q, Li S, Venkatesan R, Li P, Cao H, Gao C
Acta biomaterialia 2022 Aug;148:258-270
Acta biomaterialia 2022 Aug;148:258-270
Cypermethrin inhibits proliferation of Sertoli cells through AR involving DAB2IP/PI3K/AKT signaling pathway in vitro.
Wang Q, Wang XX, Xie JF, Yao TT, Xu LL, Wang LS, Yu Y, Xu LC
Toxicology research 2022 Aug;11(4):583-591
Toxicology research 2022 Aug;11(4):583-591
Effect of Silkworm Pupa Protein Hydrolysates on Proliferation of Gastric Cancer Cells In Vitro.
Li W, Mu L, Zou Y, Wang W, Zhao H, Wu X, Liao S
Foods (Basel, Switzerland) 2022 Aug 7;11(15)
Foods (Basel, Switzerland) 2022 Aug 7;11(15)
The Exocyst Is Required for CD36 Fatty Acid Translocase Trafficking and Free Fatty Acid Uptake in Skeletal Muscle Cells.
Nakamura NK, Tokunaga DS, Ha HY, Polgar N
Cells 2022 Aug 6;11(15)
Cells 2022 Aug 6;11(15)
Chemical profile and miscarriage prevention evaluation of Jiao-Ai Decoction, a classical traditional Chinese formula.
Zhang M, Geng T, Jing SH, Li L, Wang K, Zhang Q, Zhang Y, Zhou SK, Gao P, Ding AW, Zhang L
Journal of pharmaceutical and biomedical analysis 2022 Aug 5;217:114832
Journal of pharmaceutical and biomedical analysis 2022 Aug 5;217:114832
Inhibition of BET Family Proteins Suppresses African Swine Fever Virus Infection.
Zhao Y, Niu Q, Yang S, Yang J, Zhang Z, Geng S, Fan J, Liu Z, Guan G, Liu Z, Zhou J, Hu H, Luo J, Yin H
Microbiology spectrum 2022 Aug 31;10(4):e0241921
Microbiology spectrum 2022 Aug 31;10(4):e0241921
The mechanism on Prevotella melaninogenica promoting the inflammatory progression of oral lichen planus.
Xu P, Shao RR, Zhang S, Tan ZW, Guo YT, He Y
Clinical and experimental immunology 2022 Aug 19;209(2):215-224
Clinical and experimental immunology 2022 Aug 19;209(2):215-224
Aperture Modulation of Isoreticular Metal Organic Frameworks for Targeted Antitumor Drug Delivery.
Cai M, Liang W, Wang K, Yin D, Fu T, Zhu R, Qu C, Dong X, Ni J, Yin X
ACS applied materials & interfaces 2022 Aug 17;14(32):36366-36378
ACS applied materials & interfaces 2022 Aug 17;14(32):36366-36378
Quantitative proteomics and functional analysis identified novel targets for missed abortion.
Chen X, Zheng Q, Ji L, Zhuang Y, Yu H, Cheng X, Han Y, Lv J, Zheng B, Zheng Y, Yu J
Experimental cell research 2022 Aug 15;417(2):113216
Experimental cell research 2022 Aug 15;417(2):113216
Apextrin from Ruditapes philippinarum functions as pattern recognition receptor and modulates NF-κB pathway.
Jiang K, Nie H, Yin Z, Yan X, Li Q
International journal of biological macromolecules 2022 Aug 1;214:33-44
International journal of biological macromolecules 2022 Aug 1;214:33-44
Cognitive enhancement and neuroprotective effects of OABL, a sesquiterpene lactone in 5xFAD Alzheimer's disease mice model.
Tang JJ, Huang LF, Deng JL, Wang YM, Guo C, Peng XN, Liu Z, Gao JM
Redox biology 2022 Apr;50:102229
Redox biology 2022 Apr;50:102229
O-GlcNAc transferase promotes the nuclear localization of the focal adhesion-associated protein Zyxin to regulate UV-induced cell death.
Zhao Y, Yue S, Zhou X, Guo J, Ma S, Chen Q
The Journal of biological chemistry 2022 Apr;298(4):101776
The Journal of biological chemistry 2022 Apr;298(4):101776
Protective Effects of Scutellarin on Acute Alcohol Intestinal Injury.
Liu F, Gao X, Li Z, Zhang X, Fan H, Yu G, Bello BK, Feng X, Li D, Teng D, Chen Y, Zhao P, Fu M, Dong J
Chemistry & biodiversity 2022 Apr;19(4):e202100856
Chemistry & biodiversity 2022 Apr;19(4):e202100856
The lncRNA MIAT regulates CPT-1a mediated cardiac hypertrophy through m(6)A RNA methylation reading protein Ythdf2.
Yang Y, Mbikyo MB, Zhang J, Zhang Y, Zhang N, Li Z
Cell death discovery 2022 Apr 5;8(1):167
Cell death discovery 2022 Apr 5;8(1):167
IL-37 isoform D acts as an inhibitor of soluble ST2 to boost type 2 immune homeostasis in white adipose tissue.
Li C, Zhao M, Zhao M, Chen N, Guo Y, Du Y, Zhang Y, Cao B, Zhan B, Guo C, Li Y, Li Y, Shi Y, Zhu F, Zhang L, Wang Q
Cell death discovery 2022 Apr 5;8(1):163
Cell death discovery 2022 Apr 5;8(1):163
Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue.
Rosina M, Ceci V, Turchi R, Chuan L, Borcherding N, Sciarretta F, Sánchez-Díaz M, Tortolici F, Karlinsey K, Chiurchiù V, Fuoco C, Giwa R, Field RL, Audano M, Arena S, Palma A, Riccio F, Shamsi F, Renzone G, Verri M, Crescenzi A, Rizza S, Faienza F, Filomeni G, Kooijman S, Rufini S, de Vries AAF, Scaloni A, Mitro N, Tseng YH, Hidalgo A, Zhou B, Brestoff JR, Aquilano K, Lettieri-Barbato D
Cell metabolism 2022 Apr 5;34(4):533-548.e12
Cell metabolism 2022 Apr 5;34(4):533-548.e12
The Tobacco β-Cembrenediol: A Prostate Cancer Recurrence Suppressor Lead and Prospective Scaffold via Modulation of Indoleamine 2,3-Dioxygenase and Tryptophan Dioxygenase.
Mudhish EA, Siddique AB, Ebrahim HY, Abdelwahed KS, King JA, El Sayed KA
Nutrients 2022 Apr 4;14(7)
Nutrients 2022 Apr 4;14(7)
The plant hormone abscisic acid stimulates megakaryocyte differentiation from human iPSCs in vitro.
Huang W, Gu H, Zhan Z, Wang R, Song L, Zhang Y, Zhang Y, Li S, Li J, Zang Y, Li Y, Qian B
Platelets 2022 Apr 3;33(3):462-470
Platelets 2022 Apr 3;33(3):462-470
Map of Enteropathogenic Escherichia coli Targets Mitochondria and Triggers DRP-1-Mediated Mitochondrial Fission and Cell Apoptosis in Bovine Mastitis.
Li Y, Zhu Y, Chu B, Liu N, Chen S, Wang J, Zou Y
International journal of molecular sciences 2022 Apr 28;23(9)
International journal of molecular sciences 2022 Apr 28;23(9)
ORP5 promotes tumor metastasis via stabilizing c-Met in renal cell carcinoma.
Song L, Zhang L, Zhou Y, Shao X, Xu Y, Pei D, Wang Q
Cell death discovery 2022 Apr 21;8(1):219
Cell death discovery 2022 Apr 21;8(1):219
Age-related visual impairments and retinal ganglion cells axonal degeneration in a mouse model harboring OPTN (E50K) mutation.
Hou M, Shao Z, Zhang S, Liu X, Fan P, Jiang M, Zhao Y, Xiao R, Yuan H
Cell death & disease 2022 Apr 18;13(4):362
Cell death & disease 2022 Apr 18;13(4):362
Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma.
Chen G, Kong P, Yang M, Hu W, Prise KM, Yu KN, Cui S, Qin F, Meng G, Almahi WA, Nie L, Han W
International journal of radiation oncology, biology, physics 2022 Apr 1;112(5):1216-1228
International journal of radiation oncology, biology, physics 2022 Apr 1;112(5):1216-1228
Bioinformatic Approach to Unveil Key Differentially Expressed Proteins in Human Sperm After Slow and Rapid Cryopreservation.
Corda PO, Silva JV, Pereira SC, Barros A, Alves MG, Fardilha M
Frontiers in cell and developmental biology 2021;9:759354
Frontiers in cell and developmental biology 2021;9:759354
The Regulatory Role of GBF1 on Osteoclast Activation Through EIF2a Mediated ER Stress and Novel Marker FAM129A Induction.
Wen C, Zhou Y, Xu Y, Tan H, Pang C, Liu H, Liu K, Wei L, Luo H, Qin T, He C, Liu C, Zhou C
Frontiers in cell and developmental biology 2021;9:706768
Frontiers in cell and developmental biology 2021;9:706768
Tributyltin Oxide Exposure During in vitro Maturation Disrupts Oocyte Maturation and Subsequent Embryonic Developmental Competence in Pigs.
Xiao Y, Yuan B, Hu W, Qi J, Jiang H, Sun B, Zhang J, Liang S
Frontiers in cell and developmental biology 2021;9:683448
Frontiers in cell and developmental biology 2021;9:683448
Iron Overload-Induced Ferroptosis Impairs Porcine Oocyte Maturation and Subsequent Embryonic Developmental Competence in vitro.
Hu W, Zhang Y, Wang D, Yang T, Qi J, Zhang Y, Jiang H, Zhang J, Sun B, Liang S
Frontiers in cell and developmental biology 2021;9:673291
Frontiers in cell and developmental biology 2021;9:673291
The m(6)A Reader YTHDF1 Facilitates the Tumorigenesis and Metastasis of Gastric Cancer via USP14 Translation in an m(6)A-Dependent Manner.
Chen XY, Liang R, Yi YC, Fan HN, Chen M, Zhang J, Zhu JS
Frontiers in cell and developmental biology 2021;9:647702
Frontiers in cell and developmental biology 2021;9:647702
Mechanically Activated Calcium Channel PIEZO1 Modulates Radiation-Induced Epithelial-Mesenchymal Transition by Forming a Positive Feedback With TGF-β1.
Huang JQ, Zhang H, Guo XW, Lu Y, Wang SN, Cheng B, Dong SH, Lyu XL, Li FS, Li YW
Frontiers in molecular biosciences 2021;8:725275
Frontiers in molecular biosciences 2021;8:725275
Expression and Functional Analysis of lncRNAs Involved in Platelet-Derived Growth Factor-BB-Induced Proliferation of Human Aortic Smooth Muscle Cells.
Lin JJ, Chen W, Gong M, Xu X, Du MY, Wang SF, Yang LY, Wang Y, Liu KX, Kong P, Li B, Liu K, Li YM, Dong LH, Sun SG
Frontiers in cardiovascular medicine 2021;8:702718
Frontiers in cardiovascular medicine 2021;8:702718
Transcriptome Differences in Pig Tracheal Epithelial Cells in Response to Pasteurella Multocida Infection.
Wang X, Wang F, Lin L, Liang W, Liu S, Hua L, Wang X, Chen H, Peng Z, Wu B
Frontiers in veterinary science 2021;8:682514
Frontiers in veterinary science 2021;8:682514
DCI after Aneurysmal Subarachnoid Hemorrhage Is Related to the Expression of MFG-E8.
Chen X, Jiang Y, Liu J, Wang C, Wan D, Liang A, Leng J, Yang Y, Xiang H, Liu R
BioMed research international 2021;2021:6568477
BioMed research international 2021;2021:6568477
USP37 downregulation elevates the Chemical Sensitivity of Human Breast Cancer Cells to Adriamycin.
Qin T, Cui XY, Xiu H, Huang C, Sun ZN, Xu XM, Li LH, Yue L
International journal of medical sciences 2021;18(2):325-334
International journal of medical sciences 2021;18(2):325-334
MnSOD Lysine 68 acetylation leads to cisplatin and doxorubicin resistance due to aberrant mitochondrial metabolism.
Gao Y, Zhu Y, Tran EL, Tokars V, Dean AE, Quan S, Gius D
International journal of biological sciences 2021;17(5):1203-1216
International journal of biological sciences 2021;17(5):1203-1216
Rosuvastatin Nanomicelles Target Neuroinflammation and Improve Neurological Deficit in a Mouse Model of Intracerebral Hemorrhage.
Zi L, Zhou W, Xu J, Li J, Li N, Xu J, You C, Wang C, Tian M
International journal of nanomedicine 2021;16:2933-2947
International journal of nanomedicine 2021;16:2933-2947
GluN2A/ERK/CREB Signaling Pathway Involved in Electroacupuncture Regulating Hypothalamic-Pituitary-Adrenal Axis Hyperactivity.
Wang Y, Han J, Zhu J, Zhang M, Ju M, Du Y, Tian Z
Frontiers in neuroscience 2021;15:703044
Frontiers in neuroscience 2021;15:703044
Latent Sex Differences in CaMKII-nNOS Signaling That Underlie Antidepressant-Like Effects of Yueju-Ganmaidazao Decoction in the Hippocampus.
Yin Y, Qian S, Chen Y, Sun Y, Li Y, Yu Y, Li J, Wu Z, Yu X, Ge R, Han J, Sun D, Wu H, Liu L, Xue W, Wang W
Frontiers in behavioral neuroscience 2021;15:640258
Frontiers in behavioral neuroscience 2021;15:640258
PADI6 Regulates Trophoblast Cell Migration-Invasion Through the Hippo/YAP1 Pathway in Hydatidiform Moles.
Huang B, Zhao Y, Zhou L, Gong T, Feng J, Han P, Qian J
Journal of inflammation research 2021;14:3489-3500
Journal of inflammation research 2021;14:3489-3500
RNF128 suppresses the malignancy of colorectal cancer cells via inhibition of Wnt/β-catenin signaling.
Zhu Y, Gan Y, Zou R, Sha H, Lu Y, Zhang Y, Feng J
American journal of translational research 2021;13(12):13567-13578
American journal of translational research 2021;13(12):13567-13578
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Cai C, Hu W, Zhang Y, Hu X, Yang S, Qiu H, Wang R, Ma M, Qiu Y, Chu T
Frontiers in pharmacology 2021;12:772540
Frontiers in pharmacology 2021;12:772540
Ilexsaponin A(1) Ameliorates Diet-Induced Nonalcoholic Fatty Liver Disease by Regulating Bile Acid Metabolism in Mice.
Zhao WW, Xiao M, Wu X, Li XW, Li XX, Zhao T, Yu L, Chen XQ
Frontiers in pharmacology 2021;12:771976
Frontiers in pharmacology 2021;12:771976
Loss of Diacylglycerol Kinase α Enhances Macrophage Responsiveness.
Manigat LC, Granade ME, Taori S, Miller CA, Vass LR, Zhong XP, Harris TE, Purow BW
Frontiers in immunology 2021;12:722469
Frontiers in immunology 2021;12:722469
ZnT8 Deficiency Protects From APAP-Induced Acute Liver Injury by Reducing Oxidative Stress Through Upregulating Hepatic Zinc and Metallothioneins.
Su W, Feng M, Liu Y, Cao R, Liu Y, Tang J, Pan K, Lan R, Mao Z
Frontiers in pharmacology 2021;12:721471
Frontiers in pharmacology 2021;12:721471
The Downregulation of eIF3a Contributes to Vemurafenib Resistance in Melanoma by Activating ERK via PPP2R1B.
Jiang SL, Wang ZB, Zhu T, Jiang T, Fei JF, Liu C, Luo C, Cheng Y, Liu ZQ
Frontiers in pharmacology 2021;12:720619
Frontiers in pharmacology 2021;12:720619
CXCL5 Downregulation in Villous Tissue Is Correlated With Recurrent Spontaneous Abortion.
Zhang S, Ding J, Wang J, Yin T, Zhang Y, Yang J
Frontiers in immunology 2021;12:717483
Frontiers in immunology 2021;12:717483
Protective Effect of Remdesivir Against Pulmonary Fibrosis in Mice.
Li X, Liu R, Cui Y, Liang J, Bi Z, Li S, Miao Y, Zhang L, Li X, Zhou H, Yang C
Frontiers in pharmacology 2021;12:692346
Frontiers in pharmacology 2021;12:692346
Chlorogenic Acid Ameliorates Damage Induced by Fluorene-9-Bisphenol in Porcine Sertoli Cells.
Zhang S, Sun B, Wang D, Liu Y, Li J, Qi J, Zhang Y, Bai C, Liang S
Frontiers in pharmacology 2021;12:678772
Frontiers in pharmacology 2021;12:678772
Glycosylation of Siglec15 promotes immunoescape and tumor growth.
Wang YL, Wei MB, Zhao WW, Feng LL, Yin XK, Bai SM, Wan XB, Hung MC, Zou AZ, Wang MH, Zheng J, Qin C, Fan XJ
American journal of cancer research 2021;11(5):2291-2302
American journal of cancer research 2021;11(5):2291-2302
Human umbilical cord-derived mesenchymal stem cell therapy ameliorates lupus through increasing CD4+ T cell senescence via MiR-199a-5p/Sirt1/p53 axis.
Cheng T, Ding S, Liu S, Li Y, Sun L
Theranostics 2021;11(2):893-905
Theranostics 2021;11(2):893-905
circCDYL2, Overexpressed in Highly Migratory Colorectal Cancer Cells, Promotes Migration by Binding to Ezrin.
Li X, Wang J, Long H, Lin W, Wang H, Chen Y, Yuan Q, Li X
Frontiers in oncology 2021;11:716073
Frontiers in oncology 2021;11:716073
The Role of KDM2B and EZH2 in Regulating the Stemness in Colorectal Cancer Through the PI3K/AKT Pathway.
Sanches JGP, Song B, Zhang Q, Cui X, Yabasin IB, Ntim M, Li X, He J, Zhang Y, Mao J, Lu Y, Li L
Frontiers in oncology 2021;11:637298
Frontiers in oncology 2021;11:637298
Expression and prognostic potential of PLEK2 in head and neck squamous cell carcinoma based on bioinformatics analysis.
Wang J, Sun Z, Wang J, Tian Q, Huang R, Wang H, Wang X, Han F
Cancer medicine 2021 Sep;10(18):6515-6533
Cancer medicine 2021 Sep;10(18):6515-6533
Therapy of spinal cord injury by zinc modified gold nanoclusters via immune-suppressing strategies.
Lin S, Li D, Zhou Z, Xu C, Mei X, Tian H
Journal of nanobiotechnology 2021 Sep 20;19(1):281
Journal of nanobiotechnology 2021 Sep 20;19(1):281
TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity.
Bi J, Cheng C, Zheng C, Huang C, Zheng X, Wan X, Chen YH, Tian Z, Sun H
Science advances 2021 Sep 17;7(38):eabi6515
Science advances 2021 Sep 17;7(38):eabi6515
Protocol for nuclear export signal characterization of cGAS in mammalian cells.
Huang Y, McLean M, Liang C, Guo F
STAR protocols 2021 Sep 17;2(3):100649
STAR protocols 2021 Sep 17;2(3):100649
Yixin-Fumai granules improve sick sinus syndrome in aging mice through Nrf-2/HO-1 pathway: A new target for sick sinus syndrome.
Zhang H, Li L, Hao M, Chen K, Lu Y, Qi J, Chen W, Ren L, Cai X, Chen C, Liu Z, Zhao B, Li Z, Hou P
Journal of ethnopharmacology 2021 Sep 15;277:114254
Journal of ethnopharmacology 2021 Sep 15;277:114254
MicroRNA‑8063 targets heterogeneous nuclear ribonucleoprotein AB to inhibit the self‑renewal of colorectal cancer stem cells via the Wnt/β‑catenin pathway.
Chen ZQ, Yuan T, Jiang H, Yang YY, Wang L, Fu RM, Luo SQ, Zhang T, Wu ZY, Wen KM
Oncology reports 2021 Oct;46(4)
Oncology reports 2021 Oct;46(4)
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Li XJ, Zhang YY, Fu YH, Zhang H, Li HX, Li QF, Li HL, Tan RK, Jiang CX, Jiang W, Li ZX, Luo C, Lu BX, Dang YJ
Acta pharmacologica Sinica 2021 Oct;42(10):1556-1566
Acta pharmacologica Sinica 2021 Oct;42(10):1556-1566
Cucurbit[7]uril as a Broad-Spectrum Antiviral Agent against Diverse RNA Viruses.
Quan J, Zhang X, Ding Y, Li S, Qiu Y, Wang R, Zhou X
Virologica Sinica 2021 Oct;36(5):1165-1176
Virologica Sinica 2021 Oct;36(5):1165-1176
ZBP1-MLKL necroptotic signaling potentiates radiation-induced antitumor immunity via intratumoral STING pathway activation.
Yang Y, Wu M, Cao D, Yang C, Jin J, Wu L, Hong X, Li W, Lu L, Li J, Wang X, Meng X, Zhang Z, Cheng J, Ye Y, Xiao H, Yu J, Deng L
Science advances 2021 Oct 8;7(41):eabf6290
Science advances 2021 Oct 8;7(41):eabf6290
NORHA, a novel follicular atresia-related lncRNA, promotes porcine granulosa cell apoptosis via the miR-183-96-182 cluster and FoxO1 axis.
Yao W, Pan Z, Du X, Zhang J, Liu H, Li Q
Journal of animal science and biotechnology 2021 Oct 7;12(1):103
Journal of animal science and biotechnology 2021 Oct 7;12(1):103
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Wang D, He J, Dong J, Wu S, Liu S, Zhu H, Xu T
Cancer letters 2021 Oct 28;519:2-19
Cancer letters 2021 Oct 28;519:2-19
Frugoside delays osteoarthritis progression via inhibiting miR-155-modulated synovial macrophage M1 polarization.
Wang H, Zhang H, Fan K, Zhang D, Hu A, Zeng X, Liu YL, Tan G, Wang H
Rheumatology (Oxford, England) 2021 Oct 2;60(10):4899-4909
Rheumatology (Oxford, England) 2021 Oct 2;60(10):4899-4909
Naringin Promotes Skeletal Muscle Fiber Remodeling by the AdipoR1-APPL1-AMPK Signaling Pathway.
Li P, Zhang S, Song H, Traore SS, Li J, Raubenheimer D, Cui Z, Kou G
Journal of agricultural and food chemistry 2021 Oct 13;69(40):11890-11899
Journal of agricultural and food chemistry 2021 Oct 13;69(40):11890-11899
Comparative Proteomics of Rat Olfactory Bulb Reveal Insights into Susceptibility and Resiliency to Chronic-stress-induced Depression or Anxiety.
Liu D, Cai X, Wang L, Yi F, Liao W, Huang R, Fang C, Chen J, Zhou J
Neuroscience 2021 Oct 1;473:29-43
Neuroscience 2021 Oct 1;473:29-43
Arsenic trioxide induces expression of BCL-2 expression via NF-κB and p38 MAPK signaling pathways in BEAS-2B cells during apoptosis.
Tang J, Yao C, Liu Y, Yuan J, Wu L, Hosoi K, Yu S, Huang C, Wei H, Chen G
Ecotoxicology and environmental safety 2021 Oct 1;222:112531
Ecotoxicology and environmental safety 2021 Oct 1;222:112531
Reduced activity of intestinal surface Na(+)/H(+) exchanger NHE3 is a key factor for induction of diarrhea after PEDV infection in neonatal piglets.
Song Z, Yan T, Ran L, Niu Z, Zhang Y, Kan Z, Xu S, Zhang S, Zhang J, Zou H, Lei C
Virology 2021 Nov;563:64-73
Virology 2021 Nov;563:64-73
Tripartite motif-containing protein 16 protects against myocardial ischemia/reperfusion injury by affecting the Keap1/Nrf2 axis.
Cui Q, Yan L
Cell and tissue research 2021 Nov;386(2):349-363
Cell and tissue research 2021 Nov;386(2):349-363
EGFR and ERK activation resists flavonoid quercetin-induced anticancer activities in human cervical cancer cells in vitro.
Chen X, Xu P, Zhang H, Su X, Guo L, Zhou X, Wang J, Huang P, Zhang Q, Sun R
Oncology letters 2021 Nov;22(5):754
Oncology letters 2021 Nov;22(5):754
Guaiazulene derivative 1,2,3,4-tetrahydroazuleno[1,2-b] tropone reduces the production of ATP by inhibiting electron transfer complex II.
Kasami C, Yamaguchi JI, Inoue H
FEBS open bio 2021 Nov;11(11):2921-2932
FEBS open bio 2021 Nov;11(11):2921-2932
Vagus nerve stimulation mediates microglia M1/2 polarization via inhibition of TLR4 pathway after ischemic stroke.
Zhang L, Liu Y, Wang S, Long L, Zang Q, Ma J, Yu L, Jia G
Biochemical and biophysical research communications 2021 Nov 5;577:71-79
Biochemical and biophysical research communications 2021 Nov 5;577:71-79
A network pharmacology approach to reveal the pharmacological targets and biological mechanism of compound kushen injection for treating pancreatic cancer based on WGCNA and in vitro experiment validation.
Wu C, Huang ZH, Meng ZQ, Fan XT, Lu S, Tan YY, You LM, Huang JQ, Stalin A, Ye PZ, Wu ZS, Zhang JY, Liu XK, Zhou W, Zhang XM, Wu JR
Chinese medicine 2021 Nov 22;16(1):121
Chinese medicine 2021 Nov 22;16(1):121
Inhibition of the NLRP3 inflammasome with MCC950 prevents chronic social isolation-induced depression-like behavior in male mice.
Li W, Niu L, Liu Z, Xu X, Shi M, Zhang Y, Deng Y, He J, Xu Y, Wan W, Sun Q, Zhong X, Cao W
Neuroscience letters 2021 Nov 20;765:136290
Neuroscience letters 2021 Nov 20;765:136290
1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-κB/MAPK pathways.
Tang JJ, Wang MR, Dong S, Huang LF, He QR, Gao JM
European journal of medicinal chemistry 2021 Nov 15;224:113713
European journal of medicinal chemistry 2021 Nov 15;224:113713
Iptakalim alleviates synaptic damages via targeting mitochondrial ATP-sensitive potassium channel in depression.
Guo W, Tang ZY, Cai ZY, Zhao WE, Yang J, Wang XP, Ji J, Huang XX, Sun XL
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21581
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21581
Characterization of ALTO-encoding circular RNAs expressed by Merkel cell polyomavirus and trichodysplasia spinulosa polyomavirus.
Yang R, Lee EE, Kim J, Choi JH, Kolitz E, Chen Y, Crewe C, Salisbury NJH, Scherer PE, Cockerell C, Smith TR, Rosen L, Verlinden L, Galloway DA, Buck CB, Feltkamp MC, Sullivan CS, Wang RC
PLoS pathogens 2021 May;17(5):e1009582
PLoS pathogens 2021 May;17(5):e1009582
Extracellular vesicles-based pre-targeting strategy enables multi-modal imaging of orthotopic colon cancer and image-guided surgery.
Jing B, Qian R, Jiang D, Gai Y, Liu Z, Guo F, Ren S, Gao Y, Lan X, An R
Journal of nanobiotechnology 2021 May 22;19(1):151
Journal of nanobiotechnology 2021 May 22;19(1):151
Functional domains and amino acid residues of Japanese eel IRF1, AjIRF1, regulate its nuclear import and IFN/Mx promoter activation.
Li W, Ling L, Wang Z, Liang Y, Huang W, Nie P, Huang B
Developmental and comparative immunology 2021 Mar;116:103923
Developmental and comparative immunology 2021 Mar;116:103923
Inhibition of ERAD synergizes with FTS to eradicate pancreatic cancer cells.
Du R, Sullivan DK, Azizian NG, Liu Y, Li Y
BMC cancer 2021 Mar 6;21(1):237
BMC cancer 2021 Mar 6;21(1):237
The combination of G-CSF and AMD3100 mobilizes bone marrow-derived stem cells to protect against cisplatin-induced acute kidney injury in mice.
Chen Z, Ren X, Ren R, Wang Y, Shang J
Stem cell research & therapy 2021 Mar 24;12(1):209
Stem cell research & therapy 2021 Mar 24;12(1):209
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Han D, Xu Y, Peng WP, Feng F, Wang Z, Gu C, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
lncRNA Ttc3-209 Promotes the Apoptosis of Retinal Ganglion Cells in Retinal Ischemia Reperfusion Injury by Targeting the miR-484/Wnt8a Axis.
Zhang R, Feng Y, Lu J, Ge Y, Li H
Investigative ophthalmology & visual science 2021 Mar 1;62(3):13
Investigative ophthalmology & visual science 2021 Mar 1;62(3):13
Sesamin induces cell cycle arrest and apoptosis through p38/C-Jun N-terminal kinase mitogen-activated protein kinase pathways in human colorectal cancer cells.
Wang X, Qiao J, Zou C, Zhao Y, Huang Y
Anti-cancer drugs 2021 Mar 1;32(3):248-256
Anti-cancer drugs 2021 Mar 1;32(3):248-256
Pharmacological effects of indole alkaloids from Alstonia scholaris (L.) R. Br. on pulmonary fibrosis in vivo.
Zhao YL, Pu SB, Qi Y, Wu BF, Shang JH, Liu YP, Hu D, Luo XD
Journal of ethnopharmacology 2021 Mar 1;267:113506
Journal of ethnopharmacology 2021 Mar 1;267:113506
Glycine alleviates fluoride-induced oxidative stress, apoptosis and senescence in a porcine testicular Sertoli cell line.
Liu Y, Sun B, Zhang S, Li J, Qi J, Bai C, Zhang J, Liang S
Reproduction in domestic animals = Zuchthygiene 2021 Jun;56(6):884-896
Reproduction in domestic animals = Zuchthygiene 2021 Jun;56(6):884-896
Alternative splicing transitions associate with emerging atrophy phenotype during denervation-induced skeletal muscle atrophy.
Qiu J, Wu L, Chang Y, Sun H, Sun J
Journal of cellular physiology 2021 Jun;236(6):4496-4514
Journal of cellular physiology 2021 Jun;236(6):4496-4514
Melatonin ameliorates cypermethrin-induced impairments by regulating oxidative stress, DNA damage and apoptosis in porcine Sertoli cells.
Li J, Sun BX, Wang DL, Liu Y, Qi JJ, Nie XW, Bai CY, Zhang JB, Liang S
Theriogenology 2021 Jun;167:67-76
Theriogenology 2021 Jun;167:67-76
Resolving the graft ischemia-reperfusion injury during liver transplantation at the single cell resolution.
Wang L, Li J, He S, Liu Y, Chen H, He S, Yin M, Zou D, Chen S, Luo T, Yu X, Wan X, Huang S, Guo Z, He X
Cell death & disease 2021 Jun 8;12(6):589
Cell death & disease 2021 Jun 8;12(6):589
Ameliorative effects of eosinophil deficiency on immune response, endoplasmic reticulum stress, apoptosis, and autophagy in fungus-induced allergic lung inflammation.
Wang S, Jiang Z, Li L, Zhang J, Zhang C, Shao C
Respiratory research 2021 Jun 7;22(1):173
Respiratory research 2021 Jun 7;22(1):173
Expression of deubiquitinases in human gingiva and cultured human gingival fibroblasts.
Fu YW, Xu HZ
BMC oral health 2021 Jun 6;21(1):290
BMC oral health 2021 Jun 6;21(1):290
Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma.
Chen Z, Chen Y, Li Y, Lian W, Zheng K, Zhang Y, Zhang Y, Lin C, Liu C, Sun F, Sun X, Wang J, Zhao L, Ke Y
Cell death & disease 2021 Jun 15;12(6):615
Cell death & disease 2021 Jun 15;12(6):615
PI3K/AKT pathway mediates the antidepressant- and anxiolytic-like roles of hydrogen sulfide in streptozotocin-induced diabetic rats via promoting hippocampal neurogenesis.
Jiang W, Tang YY, Zhu WW, Li C, Zhang P, Li RQ, Chen YJ, Zou W, Tang XQ
Neurotoxicology 2021 Jul;85:201-208
Neurotoxicology 2021 Jul;85:201-208
AEG-1 Knockdown Sensitizes Glioma Cells to Radiation Through Impairing Homologous Recombination Via Targeting RFC5.
Zhao X, Sun Y, Sun X, Li J, Shi X, Liang Z, Ma Y, Zhang X
DNA and cell biology 2021 Jul;40(7):895-905
DNA and cell biology 2021 Jul;40(7):895-905
The role of SAMM50 in non-alcoholic fatty liver disease: from genetics to mechanisms.
Li Z, Shen W, Wu G, Qin C, Zhang Y, Wang Y, Song G, Xiao C, Zhang X, Deng G, Wang R, Wang X
FEBS open bio 2021 Jul;11(7):1893-1906
FEBS open bio 2021 Jul;11(7):1893-1906
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking.
Wang F, Chen X, Cheng H, Song L, Liu J, Caplan S, Zhu L, Wu JY
EMBO reports 2021 Jul 5;22(7):e52006
EMBO reports 2021 Jul 5;22(7):e52006
Theaflavin Promotes Mitochondrial Abundance and Glucose Absorption in Myotubes by Activating the CaMKK2-AMPK Signal Axis via Calcium-Ion Influx.
Qu Z, Liu A, Liu C, Tang Q, Zhan L, Xiao W, Huang J, Liu Z, Zhang S
Journal of agricultural and food chemistry 2021 Jul 28;69(29):8144-8159
Journal of agricultural and food chemistry 2021 Jul 28;69(29):8144-8159
Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model.
Duan A, Shen K, Li B, Li C, Zhou H, Kong R, Shao Y, Qin J, Yuan T, Ji J, Guo W, Wang X, Xue T, Li L, Huang X, Sun Y, Cai Z, Liu W, Liu F
Stem cell research & therapy 2021 Jul 28;12(1):427
Stem cell research & therapy 2021 Jul 28;12(1):427
Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB.
Ge W, Wang Y, Zheng S, Zhao D, Wang X, Zhang X, Hu Y
Cell death discovery 2021 Jul 26;7(1):195
Cell death discovery 2021 Jul 26;7(1):195
Attractin Gene Deficiency in Rats Leads to Impairments in Both Activity and Spatial Learning and Memory.
Li XH, Xue C, Liu MQ, Zhang MY, Zhou Y, Xiao X, Wang J, Xu XJ, Shi Y, Zhang WN
Neuroscience 2021 Jul 1;466:101-108
Neuroscience 2021 Jul 1;466:101-108
Betulinic acid attenuated bleomycin-induced pulmonary fibrosis by effectively intervening Wnt/β-catenin signaling.
Li X, Liu X, Deng R, Gao S, Jiang Q, Liu R, Li H, Miao Y, Zhai Y, Zhang S, Wang Z, Ren Y, Ning W, Zhou H, Yang C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153428
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jan;81:153428
ETV5 Regulates Hepatic Fatty Acid Metabolism Through PPAR Signaling Pathway.
Mao Z, Feng M, Li Z, Zhou M, Xu L, Pan K, Wang S, Su W, Zhang W
Diabetes 2021 Jan;70(1):214-226
Diabetes 2021 Jan;70(1):214-226
Identification and Bioinformatic Assessment of circRNA Expression After RMI1 Knockdown and Ionizing Radiation Exposure.
Sun Y, Fang L, Yang M, He N, Wang J, Zhang M, Ji K, Wang Q, Liu Y, Du L, Wang Y, Xu C, Liu Q
DNA and cell biology 2021 Jan;40(1):80-92
DNA and cell biology 2021 Jan;40(1):80-92
NADPH levels affect cellular epigenetic state by inhibiting HDAC3-Ncor complex.
Li W, Kou J, Qin J, Li L, Zhang Z, Pan Y, Xue Y, Du W
Nature metabolism 2021 Jan;3(1):75-89
Nature metabolism 2021 Jan;3(1):75-89
Libertellenone H, a Natural Pimarane Diterpenoid, Inhibits Thioredoxin System and Induces ROS-Mediated Apoptosis in Human Pancreatic Cancer Cells.
Zhang W, Zhu Y, Yu H, Liu X, Jiao B, Lu X
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
Yang J, Cao LL, Wang XP, Guo W, Guo RB, Sun YQ, Xue TF, Cai ZY, Ji J, Cheng H, Sun XL
Cell death & disease 2021 Jan 6;12(1):23
Cell death & disease 2021 Jan 6;12(1):23
TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.
Zhang HT, Zeng Q, Wu B, Lu J, Tong KL, Lin J, Liu QY, Xu L, Yang J, Liu X, Liu W, Zhang YF, Lian Q, Liu L, Gao X
Cell death & disease 2021 Jan 6;12(1):21
Cell death & disease 2021 Jan 6;12(1):21
A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA.
Sun H, Huang Y, Mei S, Xu F, Liu X, Zhao F, Yin L, Zhang D, Wei L, Wu C, Ma S, Wang J, Cen S, Liang C, Hu S, Guo F
Cell reports 2021 Jan 5;34(1):108586
Cell reports 2021 Jan 5;34(1):108586
Formaldehyde induces ferroptosis in hippocampal neuronal cells by upregulation of the Warburg effect.
Li XN, Yang SQ, Li M, Li XS, Tian Q, Xiao F, Tang YY, Kang X, Wang CY, Zou W, Zhang P, Tang XQ
Toxicology 2021 Jan 30;448:152650
Toxicology 2021 Jan 30;448:152650
CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson's disease.
Hu Z, Mao C, Wang H, Zhang Z, Zhang S, Luo H, Tang M, Yang J, Yuan Y, Wang Y, Liu Y, Fan L, Zhang Q, Yao D, Liu F, Schisler JC, Shi C, Xu Y
Aging 2021 Jan 2;13(1):1458-1472
Aging 2021 Jan 2;13(1):1458-1472
PDGF/MEK/ERK axis represses Ca(2+) clearance via decreasing the abundance of plasma membrane Ca(2+) pump PMCA4 in pulmonary arterial smooth muscle cells.
Deng L, Chen J, Wang T, Chen B, Yang L, Liao J, Chen Y, Wang J, Tang H, Yi J, Kang K, Li L, Gou D
American journal of physiology. Cell physiology 2021 Jan 1;320(1):C66-C79
American journal of physiology. Cell physiology 2021 Jan 1;320(1):C66-C79
BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.
Xue W, Yao X, Ting G, Ling J, Huimin L, Yuan Q, Chun Z, Ming Z, Yuanzhen Z
Environmental pollution (Barking, Essex : 1987) 2021 Jan 1;268(Pt B):115748
Environmental pollution (Barking, Essex : 1987) 2021 Jan 1;268(Pt B):115748
Oral Administration of Probiotic Bifidobacterium breve Improves Facilitation of Hippocampal Memory Extinction via Restoration of Aberrant Higher Induction of Neuropsin in an MPTP-Induced Mouse Model of Parkinson's Disease.
Ishii T, Furuoka H, Kaya M, Kuhara T
Biomedicines 2021 Feb 8;9(2)
Biomedicines 2021 Feb 8;9(2)
A novel tonicity-responsive microRNA miR-23a-5p modulates renal cell survival under osmotic stress through targeting heat shock protein 70 HSPA1B.
Kang K, Liao X, Li Q, Chen J, Niu Y, Zeng Y, Xia S, Zeng L, Liu S, Gou D
American journal of physiology. Cell physiology 2021 Feb 1;320(2):C225-C239
American journal of physiology. Cell physiology 2021 Feb 1;320(2):C225-C239
Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology.
Zhang Y, Chen X, Wang Q, Du C, Lu W, Yuan H, Zhang Z, Li D, Ling X, Ren X, Zhao Y, Su Q, Xing Z, Qin Y, Yang X, Shen Y, Wu H, Qi Y
Journal of molecular medicine (Berlin, Germany) 2021 Dec;99(12):1797-1813
Journal of molecular medicine (Berlin, Germany) 2021 Dec;99(12):1797-1813
Hypoxia-inducible factor-1α promotes proliferation of airway smooth muscle cells through miRNA-103-mediated signaling pathway under hypoxia.
Zhang C, Gao J, Zhu S
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):944-952
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):944-952
Integrated Metabolomics and Transcriptomics Analyses Reveal Metabolic Landscape in Neuronal Cells during JEV Infection.
Li M, Yang J, Ye C, Bian P, Yang X, Zhang H, Luo C, Xue Z, Lei Y, Lian J
Virologica Sinica 2021 Dec;36(6):1554-1565
Virologica Sinica 2021 Dec;36(6):1554-1565
Decreased NHE3 activity in intestinal epithelial cells in TGEV and PEDV-induced piglet diarrhea.
Niu Z, Zhang Y, Kan Z, Ran L, Yan T, Xu S, Zhang S, Zhang J, Zou H, Song Z
Veterinary microbiology 2021 Dec;263:109263
Veterinary microbiology 2021 Dec;263:109263
The STING antagonist H-151 ameliorates psoriasis via suppression of STING/NF-κB-mediated inflammation.
Pan Y, You Y, Sun L, Sui Q, Liu L, Yuan H, Chen C, Liu J, Wen X, Dai L, Sun H
British journal of pharmacology 2021 Dec;178(24):4907-4922
British journal of pharmacology 2021 Dec;178(24):4907-4922
Mbd2 deficiency alleviates retinal cell apoptosisvia the miR-345-5p/Atf1 axis in high glucoseinjury and streptozotocin-induced diabetic mice.
Ge Y, Zhang R, Feng Y, Lu J, Li H
Molecular therapy. Nucleic acids 2021 Dec 3;26:1201-1214
Molecular therapy. Nucleic acids 2021 Dec 3;26:1201-1214
HRD1-mediated METTL14 degradation regulates m(6)A mRNA modification to suppress ER proteotoxic liver disease.
Wei J, Harada BT, Lu D, Ma R, Gao B, Xu Y, Montauti E, Mani N, Chaudhuri SM, Gregory S, Weinberg SE, Zhang DD, Green R, He C, Fang D
Molecular cell 2021 Dec 16;81(24):5052-5065.e6
Molecular cell 2021 Dec 16;81(24):5052-5065.e6
TRPV4 inhibitor HC067047 produces antidepressant-like effect in LPS-induced depression mouse model.
Li W, Xu Y, Liu Z, Shi M, Zhang Y, Deng Y, Zhong X, Chen L, He J, Zeng J, Luo M, Cao W, Wan W
Neuropharmacology 2021 Dec 15;201:108834
Neuropharmacology 2021 Dec 15;201:108834
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
Liu C, Qu J, Wu M, Huang X, Li L
Ecotoxicology and environmental safety 2021 Dec 1;225:112792
Ecotoxicology and environmental safety 2021 Dec 1;225:112792
NOD2 deficiency confers a pro-tumorigenic macrophage phenotype to promote lung adenocarcinoma progression.
Wang Y, Miao Z, Qin X, Li B, Han Y
Journal of cellular and molecular medicine 2021 Aug;25(15):7545-7558
Journal of cellular and molecular medicine 2021 Aug;25(15):7545-7558
Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Ameliorate HaCaT Cell Photo-Aging.
Liu SJ, Meng MY, Han S, Gao H, Zhao YY, Yang Y, Lin ZY, Yang LR, Zhu K, Han R, Huang WW, Wang RQ, Yang LL, Wang WJ, Li L, Wang XD, Hou ZL, Liao LW, Yang L
Rejuvenation research 2021 Aug;24(4):283-293
Rejuvenation research 2021 Aug;24(4):283-293
Isoeucommin A attenuates kidney injury in diabetic nephropathy through the Nrf2/HO-1 pathway.
Huang Q, Ouyang DS, Liu Q
FEBS open bio 2021 Aug;11(8):2350-2363
FEBS open bio 2021 Aug;11(8):2350-2363
Cypermethrin induces Sertoli cell apoptosis through mitochondrial pathway associated with calcium.
Wang HX, Zhang R, Li Z, Wang LS, Yu Y, Wang Q, Ding Z, Zhang JP, Zhang MR, Xu LC
Toxicology research 2021 Aug;10(4):742-750
Toxicology research 2021 Aug;10(4):742-750
TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.
Huang D, Xu B, Liu L, Wu L, Zhu Y, Ghanbarpour A, Wang Y, Chen FJ, Lyu J, Hu Y, Kang Y, Zhou W, Wang X, Ding W, Li X, Jiang Z, Chen J, Zhang X, Zhou H, Li JZ, Guo C, Zheng W, Zhang X, Li P, Melia T, Reinisch K, Chen XW
Cell metabolism 2021 Aug 3;33(8):1655-1670.e8
Cell metabolism 2021 Aug 3;33(8):1655-1670.e8
The E2F1/USP11 positive feedback loop promotes hepatocellular carcinoma metastasis and inhibits autophagy by activating ERK/mTOR pathway.
Qiao L, Zhang Q, Sun Z, Liu Q, Wu Z, Hu W, Bao S, Yang Q, Liu L
Cancer letters 2021 Aug 28;514:63-78
Cancer letters 2021 Aug 28;514:63-78
High-Carbohydrate Diet Alleviates the Oxidative Stress, Inflammation and Apoptosis of Megalobrama amblycephala Following Dietary Exposure to Silver Nanoparticles.
Chen F, Zhao CY, Guan JF, Liu XC, Li XF, Xie DZ, Xu C
Antioxidants (Basel, Switzerland) 2021 Aug 25;10(9)
Antioxidants (Basel, Switzerland) 2021 Aug 25;10(9)
Triptolide impairs glycolysis by suppressing GATA4/Sp1/PFKP signaling axis in mouse Sertoli cells.
Zhang Y, Tang Y, Luo Y, Luo L, Shen F, Huang Z
Toxicology and applied pharmacology 2021 Aug 15;425:115606
Toxicology and applied pharmacology 2021 Aug 15;425:115606
KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathway.
Du W, Zhu J, Zeng Y, Liu T, Zhang Y, Cai T, Fu Y, Zhang W, Zhang R, Liu Z, Huang JA
Cell death and differentiation 2021 Apr;28(4):1284-1300
Cell death and differentiation 2021 Apr;28(4):1284-1300
HSP/HSC70 activity is required for Bombyx mori nucleopolyhedrovirus replication at the early infectious phase.
Mao F, Zhu Y, Gao X, Chen X, Ngowo J, Miao M, Quan Y, Yu W
Microbial pathogenesis 2021 Apr;153:104647
Microbial pathogenesis 2021 Apr;153:104647
Salidroside Attenuates Doxorubicin-Induced Cardiac Dysfunction Partially Through Activation of QKI/FoxO1 Pathway.
Yan F, Liu R, Zhuang X, Li R, Shi H, Gao X
Journal of cardiovascular translational research 2021 Apr;14(2):355-364
Journal of cardiovascular translational research 2021 Apr;14(2):355-364
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1.
Yang F, Zhang Y, Zhu J, Wang J, Jiang Z, Zhao C, Yang Q, Huang Y, Yao W, Pang W, Han L, Zhou J
Frontiers in bioengineering and biotechnology 2020;8:647
Frontiers in bioengineering and biotechnology 2020;8:647
Neural Tube Defects and ZIC4 Hypomethylation in Relation to Polycyclic Aromatic Hydrocarbon Exposure.
Huang Y, Lin S, Wang C, Pi X, Jin L, Li Z, Wang L, Ren A
Frontiers in cell and developmental biology 2020;8:582661
Frontiers in cell and developmental biology 2020;8:582661
Identification of Transcriptional Variation in Aortic Remodeling Using a Murine Transverse Aortic Constriction (TAC) Model.
Zhang X, Feng T, Zeng XI, Liang H, Situ B, Zhang Q, Zhou F, Chen Y, Wang T, Cai D, Lin X, Xiu J, Zheng L
Frontiers in cardiovascular medicine 2020;7:581362
Frontiers in cardiovascular medicine 2020;7:581362
Similar Repair Effects of Human Placenta, Bone Marrow Mesenchymal Stem Cells, and Their Exosomes for Damaged SVOG Ovarian Granulosa Cells.
Chen S, Wang Y, Liao L, Meng L, Li J, Shi C, Han H, Zheng X, Shen H
Stem cells international 2020;2020:8861557
Stem cells international 2020;2020:8861557
Beneficial Effects of Crocin against Depression via Pituitary Adenylate Cyclase-Activating Polypeptide.
Lu L, Wu D, Wang K, Tang J, Chen G
BioMed research international 2020;2020:3903125
BioMed research international 2020;2020:3903125
Anti-Inflammatory and Antioxidant Effect of Eucommia ulmoides Polysaccharide in Hepatic Ischemia-Reperfusion Injury by Regulating ROS and the TLR-4-NF-κB Pathway.
Gao W, Feng Z, Zhang S, Wu B, Geng X, Fan G, Duan Y, Li K, Liu K, Peng C
BioMed research international 2020;2020:1860637
BioMed research international 2020;2020:1860637
Skp2 modulates proliferation, senescence and tumorigenesis of glioma.
Wu J, Su HK, Yu ZH, Xi SY, Guo CC, Hu ZY, Qu Y, Cai HP, Zhao YY, Zhao HF, Chen FR, Huang YF, To ST, Feng BH, Sai K, Chen ZP, Wang J
Cancer cell international 2020;20:71
Cancer cell international 2020;20:71
HCK can serve as novel prognostic biomarker and therapeutic target for Breast Cancer patients.
Zhu X, Zhang Y, Bai Y, Gu X, Chen G, Sun L, Wang Y, Qiao X, Ma Q, Zhu T, Bu J, Xue J, Liu C
International journal of medical sciences 2020;17(17):2773-2789
International journal of medical sciences 2020;17(17):2773-2789
Repression of FGF signaling is responsible for Dnmt3b inhibition and impaired de novo DNA methylation during early development of in vitro fertilized embryos.
Fu W, Yue Y, Miao K, Xi G, Zhang C, Wang W, An L, Tian J
International journal of biological sciences 2020;16(15):3085-3099
International journal of biological sciences 2020;16(15):3085-3099
G Protein-Coupled Receptor 109A Maintains the Intestinal Integrity and Protects Against ETEC Mucosal Infection by Promoting IgA Secretion.
Gong Y, Jin X, Yuan B, Lv Y, Yan G, Liu M, Xie C, Liu J, Tang Y, Gao H, Zhu Y, Huang Y, Wang W
Frontiers in immunology 2020;11:583652
Frontiers in immunology 2020;11:583652
Integration of Transcriptomics and Metabolomics Reveals the Antitumor Mechanism Underlying Shikonin in Colon Cancer.
Chen Y, Gao Y, Yi X, Zhang J, Chen Z, Wu Y
Frontiers in pharmacology 2020;11:544647
Frontiers in pharmacology 2020;11:544647
Possible Roles of Proinflammatory Signaling in Keratinocytes Through Aryl Hydrocarbon Receptor Ligands for the Development of Squamous Cell Carcinoma.
Sato Y, Fujimura T, Hidaka T, Lyu C, Tanita K, Matsushita S, Yamamoto M, Aiba S
Frontiers in immunology 2020;11:534323
Frontiers in immunology 2020;11:534323
Cyclophilin A plays an important role in embryo implantation through activating Stat3.
Yu T, Lin S, Xu R, Du TX, Li Y, Gao H, Diao HL, Zhang XH
Reproduction (Cambridge, England) 2020 Sep;160(3):343-351
Reproduction (Cambridge, England) 2020 Sep;160(3):343-351
Control the fate of human umbilical cord mesenchymal stem cells with dual-enzymatically cross-linked gelatin hydrogels for potential applications in nerve regeneration.
Li J, Gao F, Ma S, Zhang Y, Zhang J, Guan F, Yao M
Journal of tissue engineering and regenerative medicine 2020 Sep;14(9):1261-1271
Journal of tissue engineering and regenerative medicine 2020 Sep;14(9):1261-1271
miR-361-5p Mediates SMAD4 to Promote Porcine Granulosa Cell Apoptosis through VEGFA.
Ma M, Zhang J, Gao X, Yao W, Li Q, Pan Z
Biomolecules 2020 Sep 4;10(9)
Biomolecules 2020 Sep 4;10(9)
Neddylation promotes protein translocation between the cytoplasm and nucleus.
Li S, Fang W, Cui Y, Shi H, Chen J, Li L, Zhang L, Zhang X
Biochemical and biophysical research communications 2020 Sep 3;529(4):991-997
Biochemical and biophysical research communications 2020 Sep 3;529(4):991-997
EPS8 regulates an NLRP3 inflammasome-independent caspase-1 activation pathway in monosodium urate crystal-treated RAW264.7 macrophages.
Chuang JP, Kao CY, Lee JC, Ling P, Maa MC, Leu TH
Biochemical and biophysical research communications 2020 Sep 24;530(3):487-493
Biochemical and biophysical research communications 2020 Sep 24;530(3):487-493
RNA-binding protein CUGBP1 controls the differential INSR splicing in molecular subtypes of breast cancer cells and affects cell aggressiveness.
Huang G, Song C, Wang N, Qin T, Sui S, Obr A, Zeng L, Wood TL, Leroith D, Li M, Wu Y
Carcinogenesis 2020 Sep 24;41(9):1294-1305
Carcinogenesis 2020 Sep 24;41(9):1294-1305
Chrysin Inhibits Melanoma Tumor Metastasis via Interfering with the FOXM1/β-Catenin Signaling.
Yufei Z, Yuqi W, Binyue H, Lingchen T, Xi C, Hoffelt D, Fuliang H
Journal of agricultural and food chemistry 2020 Sep 2;68(35):9358-9367
Journal of agricultural and food chemistry 2020 Sep 2;68(35):9358-9367
Indole alkaloids from leaves of Alstonia scholaris (L.) R. Br. protect against emphysema in mice.
Zhao YL, Yang ZF, Wu BF, Shang JH, Liu YP, Wang XH, Luo XD
Journal of ethnopharmacology 2020 Sep 15;259:112949
Journal of ethnopharmacology 2020 Sep 15;259:112949
miR-203 inhibits cell proliferation and ERK pathway in prostate cancer by targeting IRS-1.
Meng Y, Hu X, Li S, Zeng X, Qiu L, Wei M, Wang Z, Han J
BMC cancer 2020 Oct 27;20(1):1028
BMC cancer 2020 Oct 27;20(1):1028
Identification of long-term survival-associated gene in breast cancer.
Ning S, Li H, Qiao K, Wang Q, Shen M, Kang Y, Yin Y, Liu J, Liu L, Hou S, Wang J, Xu S, Pang D
Aging 2020 Oct 20;12(20):20332-20349
Aging 2020 Oct 20;12(20):20332-20349
bta-miR-23a Regulates the Myogenic Differentiation of Fetal Bovine Skeletal Muscle-Derived Progenitor Cells by Targeting MDFIC Gene.
Hu X, Xing Y, Ren L, Wang Y, Li Q, Yang Q, Du M, Xu L, Willems L, Li J, Zhang L
Genes 2020 Oct 20;11(10)
Genes 2020 Oct 20;11(10)
Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage.
Fan C, Feng J, Tang C, Zhang Z, Feng Y, Duan W, Zhai M, Yan Z, Zhu L, Feng L, Zhu H, Luo E
Stem cell research & therapy 2020 Oct 15;11(1):442
Stem cell research & therapy 2020 Oct 15;11(1):442
Efficacy of a wound-dressing biomaterial on prevention of postinflammatory hyperpigmentation after suction blister epidermal grafting in stable vitiligo patients: a controlled assessor-blinded clinical study with in vitro bioactivity investigation.
Liu Z, Jiang M, Zhao J, Wang Q, Zhang C, Gao M, Gu M, Xiang L
Archives of dermatological research 2020 Nov;312(9):635-645
Archives of dermatological research 2020 Nov;312(9):635-645
The critical role of the hippocampal NLRP3 inflammasome in social isolation-induced cognitive impairment in male mice.
Niu L, Luo SS, Xu Y, Wang Z, Luo D, Yang H, Li W, He J, Zhong XL, Liu ZH, Zeng JY, Cao WY, Wan W
Neurobiology of learning and memory 2020 Nov;175:107301
Neurobiology of learning and memory 2020 Nov;175:107301
MitoQ attenuates brain damage by polarizing microglia towards the M2 phenotype through inhibition of the NLRP3 inflammasome after ICH.
Chen W, Guo C, Huang S, Jia Z, Wang J, Zhong J, Ge H, Yuan J, Chen T, Liu X, Hu R, Yin Y, Feng H
Pharmacological research 2020 Nov;161:105122
Pharmacological research 2020 Nov;161:105122
Anti-neuroinflammatory effect of 3,4-dihydroxybenzaldehyde in ischemic stroke.
Li X, Xiang B, Shen T, Xiao C, Dai R, He F, Lin Q
International immunopharmacology 2020 May;82:106353
International immunopharmacology 2020 May;82:106353
The B7-H4 gene induces immune escape partly via upregulating the PD-1/Stat3 pathway in non-small cell lung cancer.
Yuan L, Ye J, Fan D
Human immunology 2020 May;81(5):254-261
Human immunology 2020 May;81(5):254-261
Protein target identification of ginsenosides in skeletal muscle tissues: discovery of natural small-molecule activators of muscle-type creatine kinase.
Chen F, Zhu K, Chen L, Ouyang L, Chen C, Gu L, Jiang Y, Wang Z, Lin Z, Zhang Q, Shao X, Dai J, Zhao Y
Journal of ginseng research 2020 May;44(3):461-474
Journal of ginseng research 2020 May;44(3):461-474
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, Shao X, Song N, Zhao Y, Li H, Yang G, Xu C, Wei C
Redox biology 2020 May;32:101514
Redox biology 2020 May;32:101514
Leptin mediates protection of hydrogen sulfide against 6-hydroxydopamine-induced Parkinson's disease: Involving enhancement in Warburg effect.
Yang SQ, Tian Q, Li D, He SQ, Hu M, Liu SY, Zou W, Chen YJ, Zhang P, Tang XQ
Neurochemistry international 2020 May;135:104692
Neurochemistry international 2020 May;135:104692
Neuropeptide Y1 receptor antagonist promotes osteoporosis and microdamage repair and enhances osteogenic differentiation of bone marrow stem cells via cAMP/PKA/CREB pathway.
Xie W, Li F, Han Y, Qin Y, Wang Y, Chi X, Xiao J, Li Z
Aging 2020 May 7;12(9):8120-8136
Aging 2020 May 7;12(9):8120-8136
A Novel Mechanism of bta-miR-210 in Bovine Early Intramuscular Adipogenesis.
Ren L, Li Q, Hu X, Yang Q, Du M, Xing Y, Wang Y, Li J, Zhang L
Genes 2020 May 29;11(6)
Genes 2020 May 29;11(6)
Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep.
Zhang R, Li Y, Jia K, Xu X, Li Y, Zhao Y, Zhang X, Zhang J, Liu G, Deng S, Lian Z
Cell death & disease 2020 May 29;11(5):407
Cell death & disease 2020 May 29;11(5):407
Synergistic antifibrotic effects of miR-451 with miR-185 partly by co-targeting EphB2 on hepatic stellate cells.
Chen X, Zhang D, Wang Y, Chen K, Zhao L, Xu Y, Jiang H, Wang S
Cell death & disease 2020 May 28;11(5):402
Cell death & disease 2020 May 28;11(5):402
Synthesis and biological evaluations of N'-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents.
Li B, Zhu F, He F, Huang Q, Liu X, Wu T, Zhao T, Qiu Y, Wu Z, Xue Y, Fang M
Bioorganic chemistry 2020 Mar;96:103592
Bioorganic chemistry 2020 Mar;96:103592
Mbd2 Mediates Retinal Cell Apoptosis by Targeting the lncRNA Mbd2-AL1/miR-188-3p/Traf3 Axis in Ischemia/Reperfusion Injury.
Ge Y, Zhang R, Feng Y, Li H
Molecular therapy. Nucleic acids 2020 Mar 6;19:1250-1265
Molecular therapy. Nucleic acids 2020 Mar 6;19:1250-1265
Yueju-Ganmaidazao Decoction confers rapid antidepressant-like effects and the involvement of suppression of NMDA/NO/cGMP signaling.
Zhang H, Sun Y, Qian S, Ge R, Guo X, Shen Q, Sheng L, Nie C, Zhang Y, Yao Y, Zhou T, Wang W, Xue W, Chen G
Journal of ethnopharmacology 2020 Mar 25;250:112380
Journal of ethnopharmacology 2020 Mar 25;250:112380
The developmental and experience-dependent expression of IGF-2 in mice visual cortex.
Luo Y, Liu Z, Luo S, Wang X, Tao L
Neuroscience letters 2020 Mar 16;721:134828
Neuroscience letters 2020 Mar 16;721:134828
Overexpression of NRF1-742 or NRF1-772 Reduces Arsenic-Induced Cytotoxicity and Apoptosis in Human HaCaT Keratinocytes.
Wang S, Cheng H, Wang L, Zhao R, Guan D
International journal of molecular sciences 2020 Mar 16;21(6)
International journal of molecular sciences 2020 Mar 16;21(6)
CRISPR/Cas9-mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen.
Xu Y, Liu H, Pan H, Wang X, Zhang Y, Yao B, Li N, Lai L, Li Z
Genes 2020 Mar 11;11(3)
Genes 2020 Mar 11;11(3)
Circular RNA hsa_circ_0008285 inhibits colorectal cancer cell proliferation and migration via the miR-382-5p/PTEN axis.
Wang J, Luo J, Liu G, Li X
Biochemical and biophysical research communications 2020 Jun 25;527(2):503-510
Biochemical and biophysical research communications 2020 Jun 25;527(2):503-510
Hepatic HuR modulates lipid homeostasis in response to high-fat diet.
Zhang Z, Zong C, Jiang M, Hu H, Cheng X, Ni J, Yi X, Jiang B, Tian F, Chang MW, Su W, Zhu L, Li J, Xiang X, Miao C, Gorospe M, de Cabo R, Dou Y, Ju Z, Yang J, Jiang C, Yang Z, Wang W
Nature communications 2020 Jun 16;11(1):3067
Nature communications 2020 Jun 16;11(1):3067
Melatonin regulates mitochondrial dynamics and alleviates neuron damage in prion diseases.
Zhang X, Zhao D, Wu W, Ali Shah SZ, Lai M, Yang D, Li J, Guan Z, Li W, Gao H, Zhao H, Zhou X, Yang L
Aging 2020 Jun 10;12(11):11139-11151
Aging 2020 Jun 10;12(11):11139-11151
PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition.
Dong P, Fu H, Chen L, Zhang S, Zhang X, Li H, Wu D, Ji X
Journal of cellular and molecular medicine 2020 Jul;24(14):8221-8235
Journal of cellular and molecular medicine 2020 Jul;24(14):8221-8235
A novel microRNA and its pfk target control growth length in the freshwater shrimp Neocaridina heteropoda.
Li R, Weng J, Ren L, Wang X, Meng Q, Wang L, Sun J
The Journal of experimental biology 2020 Jul 8;223(Pt 13)
The Journal of experimental biology 2020 Jul 8;223(Pt 13)
Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5.
Wang Y, Zhang X, Chen W, Gao L, Li J, Song T, Chi J, Zhang X, Shi Z, Dong Y, Yin X, Liu Y
Life sciences 2020 Jul 15;253:117726
Life sciences 2020 Jul 15;253:117726
Nucleus-located PDK1 regulates growth, invasion and migration of breast cancer cells.
Gan D, Yue S, Jiang Y, Zhang D, Shi H, Qian H, Zhou T, Fang W, Yao M, Zuo G, Chen T
Life sciences 2020 Jul 15;253:117722
Life sciences 2020 Jul 15;253:117722
Autophagy inducer activates Nrf2-ARE pathway to attenuate aberrant alveolarization in neonatal rats with bronchopulmonary dysplasia.
Zhao X, Shi Y, Zhang D, Tong X, Sun Y, Xue X, Fu J
Life sciences 2020 Jul 1;252:117662
Life sciences 2020 Jul 1;252:117662
PCNA and GSK3β interact with each other to regulate H1299 lung adenocarcinoma cells apoptosis.
Liu XH, Tang DE, Dai Y, Gao XJ, Liu LX
Neoplasma 2020 Jan;67(1):15-26
Neoplasma 2020 Jan;67(1):15-26
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Jiang YP, Ye RJ, Yang JM, Liu N, Zhang WJ, Ma L, Sun T, Niu JG, Zheng P, Yu JQ
Chemico-biological interactions 2020 Jan 5;315:108869
Chemico-biological interactions 2020 Jan 5;315:108869
Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis.
Feng J, Dai W, Mao Y, Wu L, Li J, Chen K, Yu Q, Kong R, Li S, Zhang J, Ji J, Wu J, Mo W, Xu X, Guo C
Journal of experimental & clinical cancer research : CR 2020 Jan 30;39(1):24
Journal of experimental & clinical cancer research : CR 2020 Jan 30;39(1):24
SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1-STAT3 Signaling in Human ES Cells.
Cai BH, Lee HY, Chou CK, Wu PH, Huang HC, Chao CC, Chung HY, Kannagi R
Cells 2020 Jan 10;9(1)
Cells 2020 Jan 10;9(1)
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA(2) phosphorylation in experimental ischemic stroke.
Cao C, Zhou J, Wu X, Qian Y, Hong Y, Mu J, Jin L, Zhu C, Li S
Cellular signalling 2020 Feb;66:109467
Cellular signalling 2020 Feb;66:109467
Pizotifen inhibits the proliferation and invasion of gastric cancer cells.
Jiang Y, Wang W, Wu X, Shi J
Experimental and therapeutic medicine 2020 Feb;19(2):817-824
Experimental and therapeutic medicine 2020 Feb;19(2):817-824
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABA(A) receptors.
Teoh J, Subramanian N, Pero ME, Bartolini F, Amador A, Kanber A, Williams D, Petri S, Yang M, Allen AS, Beal J, Haut SR, Frankel WN
Neurobiology of disease 2020 Feb;134:104632
Neurobiology of disease 2020 Feb;134:104632
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma.
Ding XY, Hu HY, Huang KN, Wei RQ, Min J, Qi C, Tang H, Qin X
Cancer science 2020 Feb;111(2):489-501
Cancer science 2020 Feb;111(2):489-501
NCAPG Dynamically Coordinates the Myogenesis of Fetal Bovine Tissue by Adjusting Chromatin Accessibility.
Hu X, Xing Y, Fu X, Yang Q, Ren L, Wang Y, Li Q, Li J, Zhang L
International journal of molecular sciences 2020 Feb 13;21(4)
International journal of molecular sciences 2020 Feb 13;21(4)
Sodium butyrate causes α-synuclein degradation by an Atg5-dependent and PI3K/Akt/mTOR-related autophagy pathway.
Qiao CM, Sun MF, Jia XB, Shi Y, Zhang BP, Zhou ZL, Zhao LP, Cui C, Shen YQ
Experimental cell research 2020 Feb 1;387(1):111772
Experimental cell research 2020 Feb 1;387(1):111772
Oxidative stress-mediated hepatotoxicity in rats induced by ethanol extracts of different parts of Chloranthus serratus.
Sun S, Wang Y, Du Y, Sun Q, He L, Zhu E, Li J
Pharmaceutical biology 2020 Dec;58(1):1277-1289
Pharmaceutical biology 2020 Dec;58(1):1277-1289
Regulation of indoleamine 2, 3-dioxygenase in hippocampal microglia by NLRP3 inflammasome in lipopolysaccharide-induced depressive-like behaviors.
Zhang S, Zong Y, Ren Z, Hu J, Wu X, Xiao H, Qin S, Zhou G, Ma Y, Zhang Y, Yu J, Wang K, Lu G, Liu Q
The European journal of neuroscience 2020 Dec;52(11):4586-4601
The European journal of neuroscience 2020 Dec;52(11):4586-4601
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
Chen M, Ding Y, Ke Y, Zeng Y, Liu N, Zhong Y, Hua X, Li Z, Xiong Y, Wu C, Yu H
Artificial cells, nanomedicine, and biotechnology 2020 Dec;48(1):824-833
Artificial cells, nanomedicine, and biotechnology 2020 Dec;48(1):824-833
IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2.
Wang Z, Qi Y, Wang R, Wu W, Li Z, Wang M, Liu R, Zhang C, Li W, Wang S
Journal of cellular physiology 2020 Dec;235(12):9538-9556
Journal of cellular physiology 2020 Dec;235(12):9538-9556
Inhibition of p38 MAPK regulates epileptic severity by decreasing expression levels of A1R and ENT1.
Zhou X, Chen Q, Huang H, Zhang J, Wang J, Chen Y, Peng Y, Zhang H, Zeng J, Feng Z, Xu Z
Molecular medicine reports 2020 Dec;22(6):5348-5357
Molecular medicine reports 2020 Dec;22(6):5348-5357
Tongmai formula improves cardiac function via regulating mitochondrial quality control in the myocardium with ischemia/reperfusion injury.
Zhao Y, Guo R, Li L, Li S, Fan G, Zhao X, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110897
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110897
Radiosensitization Effect of AGuIX, a Gadolinium-Based Nanoparticle, in Nonsmall Cell Lung Cancer.
Du Y, Sun H, Lux F, Xie Y, Du L, Xu C, Zhang H, He N, Wang J, Liu Y, Leduc G, Doussineau T, Ji K, Wang Q, Lin Z, Wang Y, Liu Q, Tillement O
ACS applied materials & interfaces 2020 Dec 23;12(51):56874-56885
ACS applied materials & interfaces 2020 Dec 23;12(51):56874-56885
Adiponectin protects HL-1 cardiomyocytes against rotenone-induced cytotoxicity through AMPK activation.
Li B, Zhang B, Liu N, Wu K, Ma Y, Zuo W, Ning Z, Liu Y, Sun C, Xiao Y, Tu T, Liu Q
Toxicology letters 2020 Dec 15;335:82-90
Toxicology letters 2020 Dec 15;335:82-90
Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.
Li Y, Bai L, Yu H, Cai D, Wang X, Huang B, Peng S, Huang M, Cao G, Kaz AM, Grady WM, Wang J, Luo Y
Cancer research 2020 Dec 1;80(23):5203-5215
Cancer research 2020 Dec 1;80(23):5203-5215
Blood coagulation factor VIII D1241E polymorphism leads to a weak malectin interaction and reduction of factor VIII posttranslational modification and secretion.
Jiang N, Xiao Y, Liu Y, Liu W, Liu S
Experimental cell research 2020 Dec 1;397(1):112334
Experimental cell research 2020 Dec 1;397(1):112334
Homocysteine downregulates cardiac homeobox transcription factor NKX2.5 via IGFBP5.
Lai G, Wang L, Li Z, Zhao Y
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1380-H1386
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1380-H1386
Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis.
Yang YX, Yu S, Jia BX, Liu N, Wu A
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Toxicology in vitro : an international journal published in association with BIBRA 2020 Aug;66:104838
Interplay of m(6)A and H3K27 trimethylation restrains inflammation during bacterial infection.
Wu C, Chen W, He J, Jin S, Liu Y, Yi Y, Gao Z, Yang J, Yang J, Cui J, Zhao W
Science advances 2020 Aug;6(34):eaba0647
Science advances 2020 Aug;6(34):eaba0647
WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy.
Zhang Y, You S, Tian Y, Lu S, Cao L, Sun Y, Zhang N
Journal of cellular and molecular medicine 2020 Aug;24(16):9041-9054
Journal of cellular and molecular medicine 2020 Aug;24(16):9041-9054
Myricetin ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting TGF-β signaling via targeting HSP90β.
Li X, Yu H, Liang L, Bi Z, Wang Y, Gao S, Wang M, Li H, Miao Y, Deng R, Ma L, Luan J, Li S, Liu M, Lin J, Zhou H, Yang C
Biochemical pharmacology 2020 Aug;178:114097
Biochemical pharmacology 2020 Aug;178:114097
Lnc-M2 controls M2 macrophage differentiation via the PKA/CREB pathway.
Chen Y, Li H, Ding T, Li J, Zhang Y, Wang J, Yang X, Chong T, Long Y, Li X, Gao F, Lyu X
Molecular immunology 2020 Aug;124:142-152
Molecular immunology 2020 Aug;124:142-152
Anti-Inflammatory Effect of Simonsinol on Lipopolysaccharide Stimulated RAW264.7 Cells through Inactivation of NF-κB Signaling Pathway.
Li LC, Pan ZH, Ning DS, Fu YX
Molecules (Basel, Switzerland) 2020 Aug 6;25(16)
Molecules (Basel, Switzerland) 2020 Aug 6;25(16)
Precise base editing with CC context-specificity using engineered human APOBEC3G-nCas9 fusions.
Liu Z, Chen S, Shan H, Jia Y, Chen M, Song Y, Lai L, Li Z
BMC biology 2020 Aug 31;18(1):111
BMC biology 2020 Aug 31;18(1):111
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Zou YJ, Xu JJ, Wang X, Zhu YH, Wu Q, Wang JF
Veterinary sciences 2020 Aug 14;7(3)
Veterinary sciences 2020 Aug 14;7(3)
Flavagline synthetic derivative induces senescence in glioblastoma cancer cells without being toxic to healthy astrocytes.
Harmouch E, Seitlinger J, Chaddad H, Ubeaud-Sequier G, Barths J, Saidu S, Désaubry L, Grandemange S, Massfelder T, Fuhrmann G, Fioretti F, Dontenwill M, Benkirane-Jessel N, Idoux-Gillet Y
Scientific reports 2020 Aug 13;10(1):13750
Scientific reports 2020 Aug 13;10(1):13750
Design, synthesis and biological evaluation of a novel tubulin inhibitor SKLB0565 targeting the colchicine binding site.
Hu X, Li L, Zhang Q, Wang Q, Feng Z, Xu Y, Xia Y, Yu L
Bioorganic chemistry 2020 Apr;97:103695
Bioorganic chemistry 2020 Apr;97:103695
Hypoxia induces tumor cell growth and angiogenesis in non-small cell lung carcinoma via the Akt-PDK1-HIF1α-YKL-40 pathway.
Miao Y, Wang W, Dong Y, Hu J, Wei K, Yang S, Lai X, Tang H
Translational cancer research 2020 Apr;9(4):2904-2918
Translational cancer research 2020 Apr;9(4):2904-2918
The E3 ubiquitin ligase Smurf2 regulates PARP1 stability to alleviate oxidative stress-induced injury in human umbilical vein endothelial cells.
Qian H, Zhang N, Wu B, Wu S, You S, Zhang Y, Sun Y
Journal of cellular and molecular medicine 2020 Apr;24(8):4600-4611
Journal of cellular and molecular medicine 2020 Apr;24(8):4600-4611
Monophosphoryl lipid A alleviated radiation-induced testicular injury through TLR4-dependent exosomes.
Liu Z, Cao K, Liao Z, Chen Y, Lei X, Wei Q, Liu C, Sun X, Yang Y, Cai J, Gao F
Journal of cellular and molecular medicine 2020 Apr;24(7):3917-3930
Journal of cellular and molecular medicine 2020 Apr;24(7):3917-3930
Inhibition of histone acetyltransferase GCN5 extends lifespan in both yeast and human cell lines.
Huang B, Zhong D, Zhu J, An Y, Gao M, Zhu S, Dang W, Wang X, Yang B, Xie Z
Aging cell 2020 Apr;19(4):e13129
Aging cell 2020 Apr;19(4):e13129
The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity.
Peng H, Yang F, Hu Q, Sun J, Peng C, Zhao Y, Huang C
Autophagy 2020 Apr;16(4):698-708
Autophagy 2020 Apr;16(4):698-708
Exogenous H(2)S Induces Hrd1 S-sulfhydration and Prevents CD36 Translocation via VAMP3 Ubiquitylation in Diabetic Hearts.
Yu M, Du H, Wang B, Chen J, Lu F, Peng S, Sun Y, Liu N, Sun X, Shiyun D, Zhao Y, Wang Y, Zhao D, Lu F, Zhang W
Aging and disease 2020 Apr;11(2):286-300
Aging and disease 2020 Apr;11(2):286-300
Systemic MCPIP1 deficiency in mice impairs lipid homeostasis.
Moody J, Yang C, Sedinkin J, Chang Y
Current research in pharmacology and drug discovery 2020 Apr;1:1-9
Current research in pharmacology and drug discovery 2020 Apr;1:1-9
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes.
Chen Z, Yuan SJ, Li K, Zhang Q, Li TF, An HC, Xu HZ, Yue Y, Han M, Xu YH, Komatsu N, Zhao L, Chen X
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
Journal of controlled release : official journal of the Controlled Release Society 2020 Apr 10;320:469-483
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
Xie C, Zhu J, Jiang Y, Chen J, Wang X, Geng S, Wu J, Zhong C, Li X, Meng Z
Theranostics 2019;9(16):4827-4840
Theranostics 2019;9(16):4827-4840
BH3 mimetic ABT-263 enhances the anticancer effects of apigenin in tumor cells with activating EGFR mutation.
Zhan Y, Wang Y, Qi M, Liang P, Ma Y, Li T, Li H, Dai C, An Z, Qi Y, Wu H, Shao H
Cell & bioscience 2019;9:60
Cell & bioscience 2019;9:60
The Binding of PD-L1 and Akt Facilitates Glioma Cell Invasion Upon Starvation via Akt/Autophagy/F-Actin Signaling.
Chen RQ, Xu XH, Liu F, Li CY, Li YJ, Li XR, Jiang GY, Hu F, Liu D, Pan F, Qiu XY, Chen XQ
Frontiers in oncology 2019;9:1347
Frontiers in oncology 2019;9:1347
Neuroprotective Effect of Echinacoside in Subacute Mouse Model of Parkinson's Disease.
Liang Y, Chen C, Xia B, Wu W, Tang J, Chen Q, Tang L, Yang H, Zhang Z, Lu Y, Yang Y, Zhao Y
BioMed research international 2019;2019:4379639
BioMed research international 2019;2019:4379639
Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1).
Zhang C, Wang B, Wang X, Sheng X, Cui Y
Cancer cell international 2019;19:339
Cancer cell international 2019;19:339
(-)-Epigallocatechin-3-gallate derivatives combined with cisplatin exhibit synergistic inhibitory effects on non-small-cell lung cancer cells.
Wang J, Sun P, Wang Q, Zhang P, Wang Y, Zi C, Wang X, Sheng J
Cancer cell international 2019;19:266
Cancer cell international 2019;19:266
Long-Term Effects of Zinc Deficiency and Zinc Supplementation on Developmental Seizure-Induced Brain Damage and the Underlying GPR39/ZnT-3 and MBP Expression in the Hippocampus.
Chen NN, Zhao DJ, Sun YX, Wang DD, Ni H
Frontiers in neuroscience 2019;13:920
Frontiers in neuroscience 2019;13:920
Catalpol prevents denervated muscular atrophy related to the inhibition of autophagy and reduces BAX/BCL2 ratio via mTOR pathway.
Wang Y, Shao Y, Gao Y, Wan G, Wan D, Zhu H, Qiu Y, Ye X
Drug design, development and therapy 2019;13:243-253
Drug design, development and therapy 2019;13:243-253
Lipoxin A4 Regulates Lipopolysaccharide-Induced BV2 Microglial Activation and Differentiation via the Notch Signaling Pathway.
Wu J, Ding DH, Li QQ, Wang XY, Sun YY, Li LJ
Frontiers in cellular neuroscience 2019;13:19
Frontiers in cellular neuroscience 2019;13:19
Protein kinase C-iota-mediated glycolysis promotes non-small-cell lung cancer progression.
Liu L, Lei B, Wang L, Chang C, Yang H, Liu J, Huang G, Xie W
OncoTargets and therapy 2019;12:5835-5848
OncoTargets and therapy 2019;12:5835-5848
Catalpol improves axonal outgrowth and reinnervation of injured sciatic nerve by activating Akt/mTOR pathway and regulating BDNF and PTEN expression.
Zhu H, Wang Y, Yang X, Wan G, Qiu Y, Ye X, Gao Y, Wan D
American journal of translational research 2019;11(3):1311-1326
American journal of translational research 2019;11(3):1311-1326
LXRα Promotes the Differentiation of Human Gastric Cancer Cells through Inactivation of Wnt/β-catenin Signaling.
Gao Y, Chen Z, Wang R, Tan X, Huang C, Chen G, Chen Z
Journal of Cancer 2019;10(1):156-167
Journal of Cancer 2019;10(1):156-167
A Comparative Peptidomic Characterization of Cultured Skeletal Muscle Tissues Derived From db/db Mice.
Wu Y, Han M, Wang Y, Gao Y, Cui X, Xu P, Ji C, Zhong T, You L, Zeng Y
Frontiers in endocrinology 2019;10:741
Frontiers in endocrinology 2019;10:741
TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease.
Wang Y, Zhu X, Yuan S, Wen S, Liu X, Wang C, Qu Z, Li J, Liu H, Sun L, Liu F
Frontiers in endocrinology 2019;10:603
Frontiers in endocrinology 2019;10:603
An improved Tet-on system in microRNA overexpression and CRISPR/Cas9-mediated gene editing.
Kang K, Huang L, Li Q, Liao X, Dang Q, Yang Y, Luo J, Zeng Y, Li L, Gou D
Journal of animal science and biotechnology 2019;10:43
Journal of animal science and biotechnology 2019;10:43
Anti-TGEV Miller Strain Infection Effect of Lactobacillus plantarum Supernatant Based on the JAK-STAT1 Signaling Pathway.
Wang K, Ran L, Yan T, Niu Z, Kan Z, Zhang Y, Yang Y, Xie L, Huang S, Yu Q, Wu D, Song Z
Frontiers in microbiology 2019;10:2540
Frontiers in microbiology 2019;10:2540
The Capsid Protein VP1 of Coxsackievirus B Induces Cell Cycle Arrest by Up-Regulating Heat Shock Protein 70.
Wang Y, Zhao S, Chen Y, Wang T, Dong C, Wo X, Zhang J, Dong Y, Xu W, Feng X, Qu C, Wang Y, Zhong Z, Zhao W
Frontiers in microbiology 2019;10:1633
Frontiers in microbiology 2019;10:1633
Integrating yeast chemical genomics and mammalian cell pathway analysis.
Zhou FL, Li SC, Zhu Y, Guo WJ, Shao LJ, Nelson J, Simpkins S, Yang DH, Liu Q, Yashiroda Y, Xu JB, Fan YY, Yue JM, Yoshida M, Xia T, Myers CL, Boone C, Wang MW
Acta pharmacologica Sinica 2019 Sep;40(9):1245-1255
Acta pharmacologica Sinica 2019 Sep;40(9):1245-1255
Sorafenib kills liver cancer cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids via the ATP-AMPK-mTOR-SREBP1 signaling pathway.
Liu G, Kuang S, Cao R, Wang J, Peng Q, Sun C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10089-10103
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10089-10103
The oncogenic role of CB2 in the progression of non-small-cell lung cancer.
Xu S, Ma H, Bo Y, Shao M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109080
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109080
Interactions between β-cyclodextrin and tea catechins, and potential anti-osteoclastogenesis activity of the (-)-epigallocatechin-3-gallate-β-cyclodextrin complex.
Xu H, Liu T, Xu J, Li J, Chen F, Xiang Z, Huang Y, Zhang D, Hu L, Zhang B, Zi C, Wang X, Sheng J
RSC advances 2019 Sep 3;9(48):28006-28018
RSC advances 2019 Sep 3;9(48):28006-28018
Exosomal transfer of miR-501 confers doxorubicin resistance and tumorigenesis via targeting of BLID in gastric cancer.
Liu X, Lu Y, Xu Y, Hou S, Huang J, Wang B, Zhao J, Xia S, Fan S, Yu X, Du Y, Hou L, Li Z, Ding Z, An S, Huang B, Li L, Tang J, Ju J, Guan H, Song B
Cancer letters 2019 Sep 10;459:122-134
Cancer letters 2019 Sep 10;459:122-134
USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway.
Sun H, Ou B, Zhao S, Liu X, Song L, Liu X, Wang R, Peng Z
EBioMedicine 2019 Oct;48:236-247
EBioMedicine 2019 Oct;48:236-247
Deregulated lncRNA expression profile in the mouse lung adenocarcinomas with KRAS-G12D mutation and P53 knockout.
Zhang M, Jiang N, Cui R, Du S, Ou H, Chen T, Ge R, Ma D, Zhang J
Journal of cellular and molecular medicine 2019 Oct;23(10):6978-6988
Journal of cellular and molecular medicine 2019 Oct;23(10):6978-6988
Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and hippocampi of adolescent mice.
Buck JM, O'Neill HC, Stitzel JA
Biochemical pharmacology 2019 Oct;168:438-451
Biochemical pharmacology 2019 Oct;168:438-451
Oxidation derivative of (-)-epigallocatechin-3-gallate (EGCG) inhibits RANKL-induced osteoclastogenesis by suppressing RANK signaling pathways in RAW 264.7 cells.
Xu H, Liu T, Li J, Xu J, Chen F, Hu L, Zhang B, Zi C, Wang X, Sheng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109237
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109237
HIF-1α contributes to Ang II-induced inflammatory cytokine production in podocytes.
Huang H, Fan Y, Gao Z, Wang W, Shao N, Zhang L, Yang Y, Zhu W, Chen Z, Hu J, Ding G
BMC pharmacology & toxicology 2019 Oct 17;20(1):59
BMC pharmacology & toxicology 2019 Oct 17;20(1):59
The CRISPR-Cas13a Gene-Editing System Induces Collateral Cleavage of RNA in Glioma Cells.
Wang Q, Liu X, Zhou J, Yang C, Wang G, Tan Y, Wu Y, Zhang S, Yi K, Kang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2019 Oct 16;6(20):1901299
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2019 Oct 16;6(20):1901299
An LTR retrotransposon-derived lncRNA interacts with RNF169 to promote homologous recombination.
Deng B, Xu W, Wang Z, Liu C, Lin P, Li B, Huang Q, Yang J, Zhou H, Qu L
EMBO reports 2019 Nov 5;20(11):e47650
EMBO reports 2019 Nov 5;20(11):e47650
Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury.
Mo D, Tian W, Zhang HN, Feng YD, Sun Y, Quan W, Hao XW, Wang XY, Liu XX, Li C, Cao W, Liu WJ, Li XQ
European journal of pharmacology 2019 Nov 15;863:172701
European journal of pharmacology 2019 Nov 15;863:172701
Astaxanthin inhibits proliferation and induces apoptosis of LX‑2 cells by regulating the miR‑29b/Bcl‑2 pathway.
Zhu S, Wang T, Luo F, Li H, Jia Q, He T, Wu H, Zou T
Molecular medicine reports 2019 May;19(5):3537-3547
Molecular medicine reports 2019 May;19(5):3537-3547
Sirt2 epigenetically down-regulates PDGFRα expression and promotes CG4 cell differentiation.
Fang N, Cheng J, Zhang C, Chen K, Zhang C, Hu Z, Bi R, Furber KL, Thangaraj M, Nazarali AJ, Ji S
Cell cycle (Georgetown, Tex.) 2019 May;18(10):1095-1109
Cell cycle (Georgetown, Tex.) 2019 May;18(10):1095-1109
Fuplatin: An Efficient and Low-Toxic Dual-Prodrug.
Zhang R, Song XQ, Liu RP, Ma ZY, Xu JY
Journal of medicinal chemistry 2019 May 9;62(9):4543-4554
Journal of medicinal chemistry 2019 May 9;62(9):4543-4554
Casp8 hypomethylation and neural tube defects in association with polycyclic aromatic hydrocarbon exposure.
Huang Y, Ren A, Wang L, Jin L, Lin S, Li Z, McDonald JA
Clinical epigenetics 2019 May 7;11(1):72
Clinical epigenetics 2019 May 7;11(1):72
The protective effects of XH-105 against radiation-induced intestinal injury.
Cheng Y, Dong Y, Hou Q, Wu J, Zhang W, Tian H, Li D
Journal of cellular and molecular medicine 2019 Mar;23(3):2238-2247
Journal of cellular and molecular medicine 2019 Mar;23(3):2238-2247
Leonurine promotes neurite outgrowth and neurotrophic activity by modulating the GR/SGK1 signaling pathway in cultured PC12 cells.
Meng P, Zhu Q, Yang H, Liu D, Lin X, Liu J, Fan J, Liu X, Su W, Liu L, Wang Y, Cai X
Neuroreport 2019 Mar 6;30(4):247-254
Neuroreport 2019 Mar 6;30(4):247-254
Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.
Shah SZA, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, Mangi MH, Wu W, Lai M, Zhang X, Duan Y, Wang L, Zhou X, Yang L
International journal of molecular sciences 2019 Mar 6;20(5)
International journal of molecular sciences 2019 Mar 6;20(5)
Long noncoding RNA CCAT2 promotes hepatocellular carcinoma proliferation and metastasis through up-regulation of NDRG1.
Liu Y, Wang D, Li Y, Yan S, Dang H, Yue H, Ling J, Chen F, Zhao Y, Gou L, Tang P, Huang A, Tang H
Experimental cell research 2019 Jun 1;379(1):19-29
Experimental cell research 2019 Jun 1;379(1):19-29
Protective effect of hyperoside against renal ischemia-reperfusion injury via modulating mitochondrial fission, oxidative stress, and apoptosis.
Wu L, Li Q, Liu S, An X, Huang Z, Zhang B, Yuan Y, Xing C
Free radical research 2019 Jul;53(7):727-736
Free radical research 2019 Jul;53(7):727-736
Role of Nkx2.5 in H(2)O(2)-induced Nsd1 suppression.
Liang X, Chu G, Wang L, Lai G, Zhao Y
Cell stress & chaperones 2019 Jul;24(4):697-707
Cell stress & chaperones 2019 Jul;24(4):697-707
Long-term pulmonary exposure to multi-walled carbon nanotubes promotes breast cancer metastatic cascades.
Lu X, Zhu Y, Bai R, Wu Z, Qian W, Yang L, Cai R, Yan H, Li T, Pandey V, Liu Y, Lobie PE, Chen C, Zhu T
Nature nanotechnology 2019 Jul;14(7):719-727
Nature nanotechnology 2019 Jul;14(7):719-727
Aloperine suppresses human pulmonary vascular smooth muscle cell proliferation via inhibiting inflammatory response.
Chang Z, Zhang P, Zhang M, Jun F, Hu Z, Yang J, Wu Y, Zhou R
The Chinese journal of physiology 2019 Jul-Aug;62(4):157-165
The Chinese journal of physiology 2019 Jul-Aug;62(4):157-165
PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol Efflux.
Zhou Y, Miles JR, Tavori H, Lin M, Khoshbouei H, Borchelt DR, Bazick H, Landreth GE, Lee S, Fazio S, Notterpek L
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Jul 3;39(27):5404-5418
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Jul 3;39(27):5404-5418
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Yang Y, Chen S, Tao L, Gan S, Luo H, Xu Y, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388
Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats.
Ying X, Tu W, Li S, Wu Q, Chen X, Zhou Y, Hu J, Yang G, Jiang S
Life sciences 2019 Jul 15;229:187-199
Life sciences 2019 Jul 15;229:187-199
YAP mediates the positive regulation of hnRNPK on the lung adenocarcinoma H1299 cell growth.
Xu L, Zhang T, Huang W, Liu X, Lu J, Gao X, Zhang YF, Liu L
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):677-687
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):677-687
Involvement of the microglial NLRP3 inflammasome in the anti-inflammatory effect of the antidepressant clomipramine.
Gong W, Zhang S, Zong Y, Halim M, Ren Z, Wang Y, Ma Y, Li B, Ma L, Zhou G, Yu J, Zhang J, Liu Q
Journal of affective disorders 2019 Jul 1;254:15-25
Journal of affective disorders 2019 Jul 1;254:15-25
Resveratrol protects against isoproterenol induced myocardial infarction in rats through VEGF-B/AMPK/eNOS/NO signalling pathway.
Feng L, Ren J, Li Y, Yang G, Kang L, Zhang S, Ma C, Li J, Liu J, Yang L, Qi Z
Free radical research 2019 Jan;53(1):82-93
Free radical research 2019 Jan;53(1):82-93
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA(2) phosphorylation.
Cao C, Dai L, Mu J, Wang X, Hong Y, Zhu C, Jin L, Li S
Cellular signalling 2019 Jan;53:151-161
Cellular signalling 2019 Jan;53:151-161
Matrix Metalloproteases-Mediated Cleavage on β-Dystroglycan May Play a Key Role in the Blood-Brain Barrier After Intracerebral Hemorrhage in Rats.
Zhang X, Gu Y, Li P, Jiang A, Sheng X, Jin X, Shi Y, Li G
Medical science monitor : international medical journal of experimental and clinical research 2019 Jan 28;25:794-800
Medical science monitor : international medical journal of experimental and clinical research 2019 Jan 28;25:794-800
Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells.
Shi H, Wang XL, Quan HF, Yan L, Pei XY, Wang R, Peng XD
Molecules (Basel, Switzerland) 2019 Jan 21;24(2)
Molecules (Basel, Switzerland) 2019 Jan 21;24(2)
KIAA1199 promotes metastasis of colorectal cancer cells via microtubule destabilization regulated by a PP2A/stathmin pathway.
Zhao L, Zhang D, Shen Q, Jin M, Lin Z, Ma H, Huang S, Zhou P, Wu G, Zhang T
Oncogene 2019 Feb;38(7):935-949
Oncogene 2019 Feb;38(7):935-949
Echinacoside protects against MPTP/MPP(+)-induced neurotoxicity via regulating autophagy pathway mediated by Sirt1.
Chen C, Xia B, Tang L, Wu W, Tang J, Liang Y, Yang H, Zhang Z, Lu Y, Chen G, Yang Y, Zhao Y
Metabolic brain disease 2019 Feb;34(1):203-212
Metabolic brain disease 2019 Feb;34(1):203-212
Activation of brain endothelium by Escherichia coli K1 virulence factor cglD promotes polymorphonuclear leukocyte transendothelial migration.
Zhang K, Shi MJ, Niu Z, Chen X, Wei JY, Miao ZW, Zhao WD, Chen YH
Medical microbiology and immunology 2019 Feb;208(1):59-68
Medical microbiology and immunology 2019 Feb;208(1):59-68
Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates.
Chen Z, Wang C, Li TF, Li K, Yue Y, Liu X, Xu HZ, Wen Y, Zhang Q, Han M, Komatsu N, Xu YH, Zhao L, Chen X
Nanomedicine (London, England) 2019 Feb;14(3):335-351
Nanomedicine (London, England) 2019 Feb;14(3):335-351
Structural and functional damage to the hippocampal neurovascular unit in diabetes-related depression.
Liu J, Wang YH, Li W, Liu L, Yang H, Meng P, Han YS
Neural regeneration research 2019 Feb;14(2):289-297
Neural regeneration research 2019 Feb;14(2):289-297
Exosomes from human adipose-derived stem cells promote sciatic nerve regeneration via optimizing Schwann cell function.
Chen J, Ren S, Duscher D, Kang Y, Liu Y, Wang C, Yuan M, Guo G, Xiong H, Zhan P, Wang Y, Machens HG, Chen Z
Journal of cellular physiology 2019 Dec;234(12):23097-23110
Journal of cellular physiology 2019 Dec;234(12):23097-23110
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Jiang YP, Yang JM, Ye RJ, Liu N, Zhang WJ, Ma L, Zheng P, Niu JG, Liu P, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Water-separated part of Chloranthus serratus alleviates lipopolysaccharide- induced RAW264.7 cell injury mainly by regulating the MAPK and Nrf2/HO-1 inflammatory pathways.
Sun S, Du Y, Yin C, Suo X, Wang R, Xia R, Zhang X
BMC complementary and alternative medicine 2019 Dec 2;19(1):343
BMC complementary and alternative medicine 2019 Dec 2;19(1):343
Hypoxic postconditioning activates the Wnt/β-catenin pathway and protects against transient global cerebral ischemia through Dkk1 Inhibition and GSK-3β inactivation.
Zhan L, Liu D, Wen H, Hu J, Pang T, Sun W, Xu E
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9291-9307
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9291-9307
Inhibition of dendritic spine extension through acrolein conjugation with α-, β-tubulin proteins.
Uemura T, Suzuki T, Ko K, Watanabe K, Dohmae N, Sakamoto A, Terui Y, Toida T, Kashiwagi K, Igarashi K
The international journal of biochemistry & cell biology 2019 Aug;113:58-66
The international journal of biochemistry & cell biology 2019 Aug;113:58-66
Overexpression of ANLN in lung adenocarcinoma is associated with metastasis.
Xu J, Zheng H, Yuan S, Zhou B, Zhao W, Pan Y, Qi D
Thoracic cancer 2019 Aug;10(8):1702-1709
Thoracic cancer 2019 Aug;10(8):1702-1709
Crocin induces anti-ischemia in middle cerebral artery occlusion rats and inhibits autophagy by regulating the mammalian target of rapamycin.
Huang Z, Xu J, Huang X, Sun G, Jiang R, Wu H, Shan X, Bao K, Wu Q, Wu H, Tao W
European journal of pharmacology 2019 Aug 15;857:172424
European journal of pharmacology 2019 Aug 15;857:172424
RMI1 contributes to DNA repair and to the tolerance to camptothecin.
Fang L, Sun X, Wang Y, Du L, Ji K, Wang J, He N, Liu Y, Wang Q, Zhai H, Hao J, Xu C, Liu Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Apr;33(4):5561-5570
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Apr;33(4):5561-5570
EIF4A2 interacts with the membrane protein of transmissible gastroenteritis coronavirus and plays a role in virus replication.
Song Z, Yang Y, Wang L, Wang K, Ran L, Xie Y, Huang L, Yang Z, Yuan P, Yu Q
Research in veterinary science 2019 Apr;123:39-46
Research in veterinary science 2019 Apr;123:39-46
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
Qin Z, Xiang C, Zhong F, Liu Y, Dong Q, Li K, Shi W, Ding C, Qin L, He F
Journal of experimental & clinical cancer research : CR 2019 Apr 11;38(1):154
Journal of experimental & clinical cancer research : CR 2019 Apr 11;38(1):154
NKX2-2 Suppresses Osteosarcoma Metastasis and Proliferation by Downregulating Multiple Target Genes.
Chen H, Liu W, Zhong L, Liao D, Zhang R, Kang T, Wu Y
Journal of Cancer 2018;9(17):3067-3077
Journal of Cancer 2018;9(17):3067-3077
Caffeine Promotes Conversion of Palmitic Acid to Palmitoleic Acid by Inducing Expression of fat-5 in Caenorhabditis elegans and scd1 in Mice.
Du X, Huang Q, Guan Y, Lv M, He X, Fang C, Wang X, Sheng J
Frontiers in pharmacology 2018;9:321
Frontiers in pharmacology 2018;9:321
EGFR as a Negative Regulatory Protein Adjusts the Activity and Mobility of NHE3 in the Cell Membrane of IPEC-J2 Cells With TGEV Infection.
Yang Z, Ran L, Yuan P, Yang Y, Wang K, Xie L, Huang S, Liu J, Song Z
Frontiers in microbiology 2018;9:2734
Frontiers in microbiology 2018;9:2734
Involvement of NMDA-AKT-mTOR Signaling in Rapid Antidepressant-Like Activity of Chaihu-jia-Longgu-Muli-tang on Olfactory Bulbectomized Mice.
Wang X, Zou Z, Shen Q, Huang Z, Chen J, Tang J, Xue W, Tao W, Wu H, Wang D, Chen G
Frontiers in pharmacology 2018;9:1537
Frontiers in pharmacology 2018;9:1537
Effect of Black Tea Extract and Thearubigins on Osteoporosis in Rats and Osteoclast Formation in vitro.
Liang Q, Lv M, Zhang X, Hu J, Wu Y, Huang Y, Wang X, Sheng J
Frontiers in physiology 2018;9:1225
Frontiers in physiology 2018;9:1225
Phosphorylation of IRS4 by CK1γ2 promotes its degradation by CHIP through the ubiquitin/lysosome pathway.
Li X, Zhong L, Wang Z, Chen H, Liao D, Zhang R, Zhang H, Kang T
Theranostics 2018;8(13):3643-3653
Theranostics 2018;8(13):3643-3653
Effect of decabrominated diphenyl ether exposure on spatial learning and memory, the expression and phosphorylation of hippocampal glutamate receptor subunits in adult Sprague-Dawley rats.
Xiong L, Liyue H, Fancai Z, Maoting L, Ya L, Ting H, Zhen Y, Shanshan Z, Wenwen G, Yan T
The Journal of toxicological sciences 2018;43(11):645-657
The Journal of toxicological sciences 2018;43(11):645-657
iTRAQ-Based Proteomics Analysis Reveals the Effect of Rhubarb in Rats with Ischemic Stroke.
Lin X, Liu T, Li P, He Z, Zhong Y, Cui H, Luo J, Wang Y, Tang T
BioMed research international 2018;2018:6920213
BioMed research international 2018;2018:6920213
The Protective Effect of New Compound XH-103 on Radiation-Induced GI Syndrome.
Dong Y, Cheng Y, Hou Q, Wu J, Li D, Tian H
Oxidative medicine and cellular longevity 2018;2018:3920147
Oxidative medicine and cellular longevity 2018;2018:3920147
PAX2 may induce ADAM10 expression in renal tubular epithelial cells and contribute to epithelial-to-mesenchymal transition.
Hou L, Du Y, Zhao C, Wu Y
International urology and nephrology 2018 Sep;50(9):1729-1741
International urology and nephrology 2018 Sep;50(9):1729-1741
Rapid induction of apoptosis in tumor cells treated with a new platinum(II) complex based on amino-thiazolidinone.
Song XQ, Liu YH, Shao J, Zhang ZL, Xie CZ, Qiao X, Bao WG, Xu JY
European journal of medicinal chemistry 2018 Sep 5;157:188-197
European journal of medicinal chemistry 2018 Sep 5;157:188-197
Theabrownin suppresses in vitro osteoclastogenesis and prevents bone loss in ovariectomized rats.
Liu T, Xiang Z, Chen F, Yin D, Huang Y, Xu J, Hu L, Xu H, Wang X, Sheng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1339-1347
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Oct;106:1339-1347
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Wang C, Luo H, Xu Y, Tao L, Chang C, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
Apolipoprotein E deficiency accelerates atherosclerosis development in miniature pigs.
Fang B, Ren X, Wang Y, Li Z, Zhao L, Zhang M, Li C, Zhang Z, Chen L, Li X, Liu J, Xiong Q, Zhang L, Jin Y, Liu X, Li L, Wei H, Yang H, Li R, Dai Y
Disease models & mechanisms 2018 Oct 10;11(10)
Disease models & mechanisms 2018 Oct 10;11(10)
hnRNPK modulates selective quality-control autophagy by downregulating the expression of HDAC6 in 293 cells.
Li Z, Liu X, Ma J, Zhang T, Gao X, Liu L
International journal of oncology 2018 Nov;53(5):2200-2212
International journal of oncology 2018 Nov;53(5):2200-2212
Temporal Proteomic Analysis of Pancreatic β-Cells in Response to Lipotoxicity and Glucolipotoxicity.
Li Z, Liu H, Niu Z, Zhong W, Xue M, Wang J, Yang F, Zhou Y, Zhou Y, Xu T, Hou J
Molecular & cellular proteomics : MCP 2018 Nov;17(11):2119-2131
Molecular & cellular proteomics : MCP 2018 Nov;17(11):2119-2131
Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells.
Tian T, Sun J, Wang J, Liu Y, Liu H
Oncology letters 2018 Nov;16(5):6133-6139
Oncology letters 2018 Nov;16(5):6133-6139
Horizontal transfer of exosomal CXCR4 promotes murine hepatocarcinoma cell migration, invasion and lymphangiogenesis.
Li M, Lu Y, Xu Y, Wang J, Zhang C, Du Y, Wang L, Li L, Wang B, Shen J, Tang J, Song B
Gene 2018 Nov 15;676:101-109
Gene 2018 Nov 15;676:101-109
KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.
Zhu ZC, Liu JW, Li K, Zheng J, Xiong ZQ
Oncogene 2018 May;37(22):2936-2952
Oncogene 2018 May;37(22):2936-2952
The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43.
Sun J, Hu Q, Peng H, Peng C, Zhou L, Lu J, Huang C
The Journal of biological chemistry 2018 May 25;293(21):8275-8284
The Journal of biological chemistry 2018 May 25;293(21):8275-8284
PMN inhibits colorectal cancer cells through inducing mitotic arrest and p53-dependent apoptosis via the inhibition of tubulin polymerization.
Wu X, Shen Y
Biochemical and biophysical research communications 2018 May 23;499(4):927-933
Biochemical and biophysical research communications 2018 May 23;499(4):927-933
Met is involved in TIGAR-regulated metastasis of non-small-cell lung cancer.
Shen M, Zhao X, Zhao L, Shi L, An S, Huang G, Liu J
Molecular cancer 2018 May 12;17(1):88
Molecular cancer 2018 May 12;17(1):88
Combined treatment with Dendrobium candidum and black tea extract promotes osteoprotective activity in ovariectomized estrogen deficient rats and osteoclast formation.
Wang MY, Shen C, An MF, Xie CQ, Wu X, Zhu QQ, Sun B, Huang YP, Zhao YL, Wang XJ, Sheng J
Life sciences 2018 May 1;200:31-41
Life sciences 2018 May 1;200:31-41
CCAAT/enhancer-binding protein β overexpression alleviates myocardial remodelling by regulating angiotensin-converting enzyme-2 expression in diabetes.
Tie Y, Zhai C, Zhang Y, Qin X, Yu F, Li H, Shan M, Zhang C
Journal of cellular and molecular medicine 2018 Mar;22(3):1475-1488
Journal of cellular and molecular medicine 2018 Mar;22(3):1475-1488
[USP33 suppresses lung adenocarcinoma lung cell invasion and metastasis by down-regulating SLIT2/ROBO1 signaling pathway].
Wang Y, Zhang S, Mu S, Zhang B, Ma S
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2018 Jul 30;38(8):956-961
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2018 Jul 30;38(8):956-961
PTEN-L promotes type I interferon responses and antiviral immunity.
Cao Y, Wang H, Yang L, Zhang Z, Li C, Yuan X, Bu L, Chen L, Chen Y, Li CM, Guo D
Cellular & molecular immunology 2018 Jan;15(1):48-57
Cellular & molecular immunology 2018 Jan;15(1):48-57
Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex.
Li Y, Wang L, Zhang X, Huang M, Li S, Wang X, Chen L, Jiang B, Yang Y
Neuropharmacology 2018 Jan;128:207-220
Neuropharmacology 2018 Jan;128:207-220
Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production.
Huang Y, Hua M, Cui X
Inflammation 2018 Feb;41(1):164-173
Inflammation 2018 Feb;41(1):164-173
Synergistic neuroprotective effect of rasagiline and idebenone against retinal ischemia-reperfusion injury via the Lin28-let-7-Dicer pathway.
Lei D, Shao Z, Zhou X, Yuan H
Oncotarget 2018 Feb 23;9(15):12137-12153
Oncotarget 2018 Feb 23;9(15):12137-12153
Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice.
Wang B, Zhang G, Yang M, Liu N, Li YX, Ma H, Ma L, Sun T, Tan H, Yu J
Neurochemical research 2018 Dec;43(12):2404-2422
Neurochemical research 2018 Dec;43(12):2404-2422
The antidepressant effects of ɑ-tocopherol are related to activation of autophagy via the AMPK/mTOR pathway.
Huang X, Wu H, Jiang R, Sun G, Shen J, Ma M, Ma C, Zhang S, Huang Z, Wu Q, Chen G, Tao W
European journal of pharmacology 2018 Aug 15;833:1-7
European journal of pharmacology 2018 Aug 15;833:1-7
Pu-erh Tea Extract Ameliorates Ovariectomy-Induced Osteoporosis in Rats and Suppresses Osteoclastogenesis In Vitro.
Liu T, Ding S, Yin D, Cuan X, Xie C, Xu H, Wang X, Sheng J
Frontiers in pharmacology 2017;8:324
Frontiers in pharmacology 2017;8:324
Role of the Ubiquitin C-Terminal Hydrolase L1-Modulated Ubiquitin Proteasome System in Auditory Cortex Senescence.
Zhang Y, Huang X, Zhao XY, Hu YJ, Sun HY, Kong WJ
ORL; journal for oto-rhino-laryngology and its related specialties 2017;79(3):153-163
ORL; journal for oto-rhino-laryngology and its related specialties 2017;79(3):153-163
Neural Plasticity Associated with Hippocampal PKA-CREB and NMDA Signaling Is Involved in the Antidepressant Effect of Repeated Low Dose of Yueju Pill on Chronic Mouse Model of Learned Helplessness.
Zou Z, Chen Y, Shen Q, Guo X, Zhang Y, Chen G
Neural plasticity 2017;2017:9160515
Neural plasticity 2017;2017:9160515
Tail Nerve Electrical Stimulation and Electro-Acupuncture Can Protect Spinal Motor Neurons and Alleviate Muscle Atrophy after Spinal Cord Transection in Rats.
Zhang YT, Jin H, Wang JH, Wen LY, Yang Y, Ruan JW, Zhang SX, Ling EA, Ding Y, Zeng YS
Neural plasticity 2017;2017:7351238
Neural plasticity 2017;2017:7351238
Regulatory Axis of miR-195/497 and HMGA1-Id3 Governs Muscle Cell Proliferation and Differentiation.
Qiu H, Zhong J, Luo L, Tang Z, Liu N, Kang K, Li L, Gou D
International journal of biological sciences 2017;13(2):157-166
International journal of biological sciences 2017;13(2):157-166
2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G(2)/M cell cycle arrest through generation of thiol oxidative stress in human esophageal cancer cells.
Li X, Jiang Z, Feng J, Zhang X, Wu J, Chen W
Oncotarget 2017 Sep 22;8(37):61846-61860
Oncotarget 2017 Sep 22;8(37):61846-61860
Nrf2 Promotes Keratinocyte Proliferation in Psoriasis through Up-Regulation of Keratin 6, Keratin 16, and Keratin 17.
Yang L, Fan X, Cui T, Dang E, Wang G
The Journal of investigative dermatology 2017 Oct;137(10):2168-2176
The Journal of investigative dermatology 2017 Oct;137(10):2168-2176
Synthesis of β-tubulin occurs within chromatoid body of round spermatids.
Fujii Y, Fujita H, Yokota S
Cytoskeleton (Hoboken, N.J.) 2017 May;74(5):197-204
Cytoskeleton (Hoboken, N.J.) 2017 May;74(5):197-204
PRAS40 alleviates neurotoxic prion peptide-induced apoptosis via mTOR-AKT signaling.
Yang W, Yang LF, Song ZQ, Shah SZA, Cui YY, Li CS, Zhao HF, Gao HL, Zhou XM, Zhao DM
CNS neuroscience & therapeutics 2017 May;23(5):416-427
CNS neuroscience & therapeutics 2017 May;23(5):416-427
High expression of ubiquitin-specific peptidase 39 is associated with the development of vascular remodeling.
He S, Zhong W, Yin L, Wang Y, Qiu Z, Song G
Molecular medicine reports 2017 May;15(5):2567-2573
Molecular medicine reports 2017 May;15(5):2567-2573
Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages.
Fang W, Bi D, Zheng R, Cai N, Xu H, Zhou R, Lu J, Wan M, Xu X
Scientific reports 2017 May 10;7(1):1663
Scientific reports 2017 May 10;7(1):1663
MicroRNA-17-92 Regulates the Transcription Factor E2F3b during Myogenesis In Vitro and In Vivo.
Tang Z, Liu N, Luo L, Kang K, Li L, Ni R, Qiu H, Gou D
International journal of molecular sciences 2017 Mar 31;18(4)
International journal of molecular sciences 2017 Mar 31;18(4)
CBX3 promotes colon cancer cell proliferation by CDK6 kinase-independent function during cell cycle.
Fan Y, Li H, Liang X, Xiang Z
Oncotarget 2017 Mar 21;8(12):19934-19946
Oncotarget 2017 Mar 21;8(12):19934-19946
cMyBP-C was decreased via KLHL3-mediated proteasomal degradation in congenital heart diseases.
Wang L, Lai G, Chu G, Liang X, Zhao Y
Experimental cell research 2017 Jun 1;355(1):18-25
Experimental cell research 2017 Jun 1;355(1):18-25
ERK1/2-mediated Cytoplasmic Accumulation of hnRNPK Antagonizes TRAIL-induced Apoptosis through Upregulation of XIAP in H1299 Cells.
Huang WS, Xu FM, Zeng QZ, Liu XH, Gao XJ, Liu LX
Biomedical and environmental sciences : BES 2017 Jul;30(7):473-481
Biomedical and environmental sciences : BES 2017 Jul;30(7):473-481
Abl2 kinase phosphorylates Bi-organellar regulator MNRR1 in mitochondria, stimulating respiration.
Aras S, Arrabi H, Purandare N, Hüttemann M, Kamholz J, Züchner S, Grossman LI
Biochimica et biophysica acta. Molecular cell research 2017 Feb;1864(2):440-448
Biochimica et biophysica acta. Molecular cell research 2017 Feb;1864(2):440-448
20-Hydroxyeicosatetraenoic acid regulates the expression of Nedd4‑2 in kidney and liver through a neddylation modification pathway.
Zhao J, Zhang B, Lai G, Xu R, Chu G, Zhao Y
Molecular medicine reports 2017 Dec;16(6):9671-9677
Molecular medicine reports 2017 Dec;16(6):9671-9677
miR-34b Modulates Skeletal Muscle Cell Proliferation and Differentiation.
Tang Z, Qiu H, Luo L, Liu N, Zhong J, Kang K, Gou D
Journal of cellular biochemistry 2017 Dec;118(12):4285-4295
Journal of cellular biochemistry 2017 Dec;118(12):4285-4295
Alginate enhances Toll-like receptor 4-mediated phagocytosis by murine RAW264.7 macrophages.
Bi D, Zhou R, Cai N, Lai Q, Han Q, Peng Y, Jiang Z, Tang Z, Lu J, Bao W, Xu H, Xu X
International journal of biological macromolecules 2017 Dec;105(Pt 2):1446-1454
International journal of biological macromolecules 2017 Dec;105(Pt 2):1446-1454
Knockdown of RMI1 impairs DNA repair under DNA replication stress.
Xu C, Fang L, Kong Y, Xiao C, Yang M, Du LQ, Liu Q
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):158-164
Biochemical and biophysical research communications 2017 Dec 9;494(1-2):158-164
Overexpression of DBC1, correlated with poor prognosis, is a potential therapeutic target for hepatocellular carcinoma.
Li C, Liao J, Wu S, Fan J, Peng Z, Wang Z
Biochemical and biophysical research communications 2017 Dec 16;494(3-4):511-517
Biochemical and biophysical research communications 2017 Dec 16;494(3-4):511-517
LL-37-induced human mast cell activation through G protein-coupled receptor MrgX2.
Yu Y, Zhang Y, Zhang Y, Lai Y, Chen W, Xiao Z, Zhang W, Jin M, Yu B
International immunopharmacology 2017 Aug;49:6-12
International immunopharmacology 2017 Aug;49:6-12
The mechanically activated p38/MMP-2 signaling pathway promotes bone marrow mesenchymal stem cell migration in rats.
Yang Z, Wu B, Jia S, Zhao Y, Hou R, Liu X, Wang X, Chen L, Yang X, Lei D, Wang L
Archives of oral biology 2017 Apr;76:55-60
Archives of oral biology 2017 Apr;76:55-60
Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.
Shah SZA, Zhao D, Taglialatela G, Khan SH, Hussain T, Dong H, Lai M, Zhou X, Yang L
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2017 Apr;14(2):463-483
The DEAD-Box RNA Helicase DDX3 Interacts with NF-κB Subunit p65 and Suppresses p65-Mediated Transcription.
Xiang N, He M, Ishaq M, Gao Y, Song F, Guo L, Ma L, Sun G, Liu D, Guo D, Chen Y
PloS one 2016;11(10):e0164471
PloS one 2016;11(10):e0164471
Six2 Is a Coordinator of LiCl-Induced Cell Proliferation and Apoptosis.
Liu J, Ju P, Zhou Y, Zhao Y, Xie Y, Long Y, Gu Y, Ni D, Lyv Z, Mao Z, Hao J, Li Y, Wan Q, Kanyomse Q, Liu Y, Xiang Y, Wang R, Chen X, Zhang J, Liu X, Zhao H, Zhou Q, Li G
International journal of molecular sciences 2016 Sep 8;17(9)
International journal of molecular sciences 2016 Sep 8;17(9)
RETRACTED: MicroRNA-378 Alleviates Cerebral Ischemic Injury by Negatively Regulating Apoptosis Executioner Caspase-3.
Zhang N, Zhong J, Han S, Li Y, Yin Y, Li J
International journal of molecular sciences 2016 Sep 2;17(9)
International journal of molecular sciences 2016 Sep 2;17(9)
Up-regulation of miR-95-3p in hepatocellular carcinoma promotes tumorigenesis by targeting p21 expression.
Ye J, Yao Y, Song Q, Li S, Hu Z, Yu Y, Hu C, Da X, Li H, Chen Q, Wang QK
Scientific reports 2016 Oct 4;6:34034
Scientific reports 2016 Oct 4;6:34034
Senkyunolide I attenuates oxygen-glucose deprivation/reoxygenation-induced inflammation in microglial cells.
Hu YY, Wang Y, Liang S, Yu XL, Zhang L, Feng LY, Feng Y
Brain research 2016 Oct 15;1649(Pt A):123-131
Brain research 2016 Oct 15;1649(Pt A):123-131
Conventional protein kinase Cβ-mediated phosphorylation inhibits collapsin response-mediated protein 2 proteolysis and alleviates ischemic injury in cultured cortical neurons and ischemic stroke-induced mice.
Yang X, Zhang X, Li Y, Han S, Howells DW, Li S, Li J
Journal of neurochemistry 2016 May;137(3):446-59
Journal of neurochemistry 2016 May;137(3):446-59
The tumor suppressor PTEN has a critical role in antiviral innate immunity.
Li S, Zhu M, Pan R, Fang T, Cao YY, Chen S, Zhao X, Lei CQ, Guo L, Chen Y, Li CM, Jokitalo E, Yin Y, Shu HB, Guo D
Nature immunology 2016 Mar;17(3):241-9
Nature immunology 2016 Mar;17(3):241-9
Hen egg white ovomacroglobulin promotes fibroblast migration via mediating cell adhesion and cytoskeleton.
Geng F, Huang X, Ma M
Journal of the science of food and agriculture 2016 Jul;96(9):3188-94
Journal of the science of food and agriculture 2016 Jul;96(9):3188-94
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
Tao X, Sun X, Xu L, Yin L, Han X, Qi Y, Xu Y, Zhao Y, Wang C, Peng J
Nutrients 2016 Jul 8;8(7)
Nutrients 2016 Jul 8;8(7)
Tubb3 regulation by the Erk and Akt signaling pathways: a mechanism involved in the effect of arginine ADP-ribosyltransferase 1 (Art1) on apoptosis of colon carcinoma CT26 cells.
Xiao M, Tang Y, Chen WW, Wang YL, Yang L, Li X, Song GL, Kuang J
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Feb;37(2):2353-63
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Feb;37(2):2353-63
Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers.
Wilcox KC, Marunde MR, Das A, Velasco PT, Kuhns BD, Marty MT, Jiang H, Luan CH, Sligar SG, Klein WL
PloS one 2015;10(4):e0125263
PloS one 2015;10(4):e0125263
Inhibition of autophagy by 3-MA enhances IL-24-induced apoptosis in human oral squamous cell carcinoma cells.
Li J, Yang D, Wang W, Piao S, Zhou J, Saiyin W, Zheng C, Sun H, Li Y
Journal of experimental & clinical cancer research : CR 2015 Sep 11;34(1):97
Journal of experimental & clinical cancer research : CR 2015 Sep 11;34(1):97
Expression of Iodotyrosine Deiodinase in Thyroid and Other Organs in Iodine-Deficient and Iodine-Excess Rats.
Sun X, Zhang X, Jiang Y, Bao S, Shan Z, Teng W
Biological trace element research 2015 Oct;167(2):272-9
Biological trace element research 2015 Oct;167(2):272-9
Regulation of signal transducer and activator of transcription 3 and apoptotic pathways by betaine attenuates isoproterenol-induced acute myocardial injury in rats.
Zheng P, Liu J, Mai S, Yuan Y, Wang Y, Dai G
Human & experimental toxicology 2015 May;34(5):538-47
Human & experimental toxicology 2015 May;34(5):538-47
SCD1 negatively regulates autophagy-induced cell death in human hepatocellular carcinoma through inactivation of the AMPK signaling pathway.
Huang GM, Jiang QH, Cai C, Qu M, Shen W
Cancer letters 2015 Mar 28;358(2):180-190
Cancer letters 2015 Mar 28;358(2):180-190
Expression and localization of estrogen receptor in human breast cancer and its clinical significance.
Li L, Wang Q, Lv X, Sha L, Qin H, Wang L, Li L
Cell biochemistry and biophysics 2015 Jan;71(1):63-8
Cell biochemistry and biophysics 2015 Jan;71(1):63-8
Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo.
Xiao W, Jiang Y, Men Q, Yuan L, Huang Z, Liu T, Li W, Liu X
International journal of oncology 2015 Jan;46(1):360-8
International journal of oncology 2015 Jan;46(1):360-8
Quantitative proteomic study of myocardial mitochondria in urea transporter B knockout mice.
Du Y, Meng Y, Zhu J, Kang L, Jia X, Guo L, Zhang L, Ye M, Hu L, Zhao X, Gu J, Yang B, Zou H
Proteomics 2014 Sep;14(17-18):2072-83
Proteomics 2014 Sep;14(17-18):2072-83
The mechanisms of EGFR in the regulation of axon regeneration.
Xu MF, Zhou H, Hu CY, Liang YQ, Hu L, Chen D
Cell biochemistry and function 2014 Jan;32(1):101-5
Cell biochemistry and function 2014 Jan;32(1):101-5
CXXC5 Associates with Smads to Mediate TNF-α Induced Apoptosis.
Wang X, Liao P, Fan X, Wan Y, Wang Y, Li Y, Jiang Z, Ye X, Mo X, Ocorr K, Deng Y, Wu X, Yuan W
Current molecular medicine 2013 Sep;13(8):1385-96
Current molecular medicine 2013 Sep;13(8):1385-96
Downregulation of miR-181b in mouse brain following ischemic stroke induces neuroprotection against ischemic injury through targeting heat shock protein A5 and ubiquitin carboxyl-terminal hydrolase isozyme L1.
Peng Z, Li J, Li Y, Yang X, Feng S, Han S, Li J
Journal of neuroscience research 2013 Oct;91(10):1349-62
Journal of neuroscience research 2013 Oct;91(10):1349-62
Modulation of calcineurin activity in mouse brain by chronic oral administration of cyclosporine A.
Liu H, Tu L, Wang Q, Sun Y, Ma Y, Cen J, Wei Q, Luo J
IUBMB life 2013 May;65(5):445-53
IUBMB life 2013 May;65(5):445-53
Effect of pioglitazone on altered expression of Aβ metabolism-associated molecules in the brain of fructose-drinking rats, a rodent model of insulin resistance.
Luo D, Hou X, Hou L, Wang M, Xu S, Dong C, Liu X
European journal of pharmacology 2011 Aug 16;664(1-3):14-9
European journal of pharmacology 2011 Aug 16;664(1-3):14-9
Mutational analysis of ErbB2 intracellular localization.
Chen L, Qian L, Zhang Z, Shi M, Song Y, Yuan G, Zhang H, Hu M, Yu M, Zhang X, Shen B, Guo N
Histochemistry and cell biology 2007 Nov;128(5):473-83
Histochemistry and cell biology 2007 Nov;128(5):473-83
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10094-1-AP(tubulin-beta antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using 10094-1-AP and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-tubulin-beta (IP:10094-1-AP, 3ug; Detection:10094-1-AP 1:1000) with mouse brain tissue lysate 7500ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded rat brain using 10094-1-AP(tubulin-beta antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded rat brain using 10094-1-AP(tubulin-beta antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
