60052

antibody from STEMCELL Technologies Inc

Targeting: TUBB3 beta-4, CFEOM3, CFEOM3A, FEOM3

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

60052

Provider

STEMCELL Technologies Inc

Product name

Anti-Beta-Tubulin III Antibody, Clone TUJ1

Antibody type

Monoclonal

Description

The TUJ1 antibody reacts with beta-tubulin III, an ~50 - 55 kDa structural protein that is a component of tubulin. Tubulin is the major component of microtubules within the cytoskeleton and is assembled from heterodimers of alpha and beta tubulin subunits. The beta III isoform of tubulin, also known as neuron-specific class III beta-tubulin, is expressed primarily in neurons and is widely used as a marker to distinguish neurons from other cell types. Beta-tubulin III contributes to microtubule formation in neuronal cell bodies and axons, a function involving GTP binding, and plays roles in axonal transport, neuronal cell proliferation, and differentiation. It is highly expressed in several types of cancer and is a predictive and prognostic marker for various tumors, for example, being found in neoplastic but not in normal glial cells. The TUJ1 antibody is expected to recognize all mammalian homologs of beta-tubulin III and the epitope has reportedly been mapped to the C-terminal 15 amino acids of the protein.

Reactivity

Human, Mouse, Rat, Other

Isotype

IgG

Vial size

250 µL

Storage

2 - 8°C