Tissue expression
Cell line expression
Protein structure
KLHL24
Kelch like family member 24DRE1, FLJ20059
The protein encoded by this gene is a ubiquitin ligase substrate receptor and is regulated by autoubiquitination. Variations in the translation initiation codon of this gene have been found, which result in an N-terminally truncated but more stable protein due to loss of the autoubiquitination function. The more stable mutant protein causes an increased ubiquitin and degradation of keratin 14, which leads to skin fragility and the potentially life-threatening disease epidermolysis bullosa. The encoded protein is also involved in the regulation of kainate receptors. [provided by RefSeq, Mar 2017]
Top validated antibodies |
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antibodies-online | ABIN873094 | Polyclonal |
WB
ICC
IHC
|
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Invitrogen Antibodies | BS-8050R | Polyclonal |
WB
EL
IHC
|
||
Aviva Systems Biology | OAAB02655 | Polyclonal |
WB
EL
IHC
|
||
Biorbyt | orb1416789 | Polyclonal |
WB
ICC
IHC
|
||
LSBio | LS-C165572 | Polyclonal |
WB
IHC |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider