Tissue expression
Cell line expression
Protein structure
DDX3Y
DEAD-box helicase 3 Y-linkedDBY
The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular interactions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of this gene is not complemented by DDX3X. Mutations in this gene result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both this gene and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
Top validated antibodies |
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Proteintech Group | 14041-1-AP | 1 references | Polyclonal |
WB
EL
ICC
IHC |
|
antibodies-online | ABIN394152 | 5 references | Monoclonal |
WB
EL
IHC
|
|
Invitrogen Antibodies | PA5-22050 | 1 references | Polyclonal |
WB
ICC
OA
|
|
NovoPro Bioscience Inc. | 109829 | Polyclonal |
WB
EL
ICC
IHC |
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Cusabio Biotech Co., Ltd | CSB-PA006622GA01HU | Polyclonal |
WB
EL
ICC
IHC |
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Supportive data in Antibodypedia
Data presented on provider website
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Recommended by provider