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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Product number
- 27334-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- IFT74 antibody
- Antibody type
- Polyclonal
- Description
- IFT74 antibody (Cat. #27334-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The IFT81-IFT74 complex acts as an unconventional RabL2 GTPase-activating protein during intraflagellar transport.
Defective airway intraflagellar transport underlies a combined motile and primary ciliopathy syndrome caused by IFT74 mutations.
Biallelic variants in IQCN cause sperm flagellar assembly defects and male infertility.
Endothelial β-arrestins regulate mechanotransduction by the type II bone morphogenetic protein receptor in primary cilia.
IQCN disruption causes fertilization failure and male infertility due to manchette assembly defect.
Disrupted intraflagellar transport due to IFT74 variants causes Joubert syndrome.
Boegholm N, Petriman NA, Loureiro-López M, Wang J, Vela MIS, Liu B, Kanie T, Ng R, Jackson PK, Andersen JS, Lorentzen E
The EMBO journal 2023 Sep 18;42(18):e111807
The EMBO journal 2023 Sep 18;42(18):e111807
Defective airway intraflagellar transport underlies a combined motile and primary ciliopathy syndrome caused by IFT74 mutations.
Fassad MR, Rumman N, Junger K, Patel MP, Thompson J, Goggin P, Ueffing M, Beyer T, Boldt K, Lucas JS, Mitchison HM
Human molecular genetics 2023 Oct 17;32(21):3090-3104
Human molecular genetics 2023 Oct 17;32(21):3090-3104
Biallelic variants in IQCN cause sperm flagellar assembly defects and male infertility.
Li Q, Wang Y, Zheng W, Guo J, Zhang S, Gong F, Lu GX, Lin G, Dai J
Human reproduction (Oxford, England) 2023 Jul 5;38(7):1390-1398
Human reproduction (Oxford, England) 2023 Jul 5;38(7):1390-1398
Endothelial β-arrestins regulate mechanotransduction by the type II bone morphogenetic protein receptor in primary cilia.
Park S, Ma Z, Zarkada G, Papangeli I, Paluri S, Nazo N, Rivera-Molina F, Toomre D, Rajagopal S, Chun HJ
Pulmonary circulation 2022 Oct;12(4):e12167
Pulmonary circulation 2022 Oct;12(4):e12167
IQCN disruption causes fertilization failure and male infertility due to manchette assembly defect.
Dai J, Li Q, Zhou Q, Zhang S, Chen J, Wang Y, Guo J, Gu Y, Gong F, Tan Y, Lu G, Zheng W, Lin G
EMBO molecular medicine 2022 Dec 7;14(12):e16501
EMBO molecular medicine 2022 Dec 7;14(12):e16501
Disrupted intraflagellar transport due to IFT74 variants causes Joubert syndrome.
Luo M, Lin Z, Zhu T, Jin M, Meng D, He R, Cao Z, Shen Y, Lu C, Cai R, Zhao Y, Wang X, Li H, Wu S, Zou X, Luo G, Cao L, Huang M, Jiao H, Gao H, Sui R, Zhao C, Ma X, Cao M
Genetics in medicine : official journal of the American College of Medical Genetics 2021 Jun;23(6):1041-1049
Genetics in medicine : official journal of the American College of Medical Genetics 2021 Jun;23(6):1041-1049
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