Antibody data
- Antibody Data
- Antigen structure
- References [29]
- Comments [0]
- Validations [0]
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- Product number
- 66948-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- TMEM119 antibody
- Antibody type
- Monoclonal
- Description
- TMEM119 antibody (Cat. #66948-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Pig, Mouse, Rat and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1E7A2
- Vial size
- 20ul, 150ul
Submitted references Spi1 regulates the microglial/macrophage inflammatory response via the PI3K/AKT/mTOR signaling pathway after intracerebral hemorrhage.
Panax quinquefolium saponins attenuates microglia activation following acute cerebral ischemia-reperfusion injury via Nrf2/miR-103-3p/TANK pathway.
TNF-α Levels Are Increased in Patients with Subjective Cognitive Impairment and Are Negatively Correlated with β Amyloid-42.
TMEM119 (c.G143A, p.S48L) Mutation Is Involved in Primary Failure of Eruption by Attenuating Glycolysis-Mediated Osteogenesis.
Prebiotic diet normalizes aberrant immune and behavioral phenotypes in a mouse model of autism spectrum disorder.
Defective neurite elongation and branching in Nibp/Trappc9 deficient zebrafish and mice.
Primary cilia-mediated regulation of microglial secretion in Alzheimer's disease.
HC067047 Ameliorates Sepsis-associated Encephalopathy by Suppressing Endoplasmic Reticulum Stress and Oxidative Stress-Induced Pyroptosis in the Hippocampi of Mice.
Microglial targeted therapy relieves cognitive impairment caused by Cntnap4 deficiency.
Resolvin D1 reprograms energy metabolism to promote microglia to phagocytize neutrophils after ischemic stroke.
Plasma derived extracellular vesicle biomarkers of microglia activation in an experimental stroke model.
Fibrinogen primes the microglial NLRP3 inflammasome and propagates pro-inflammatory signaling via extracellular vesicles: Implications for blood-brain barrier dysfunction.
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
Differential Effects of APOE Genotype on MicroRNA Cargo of Cerebrospinal Fluid Extracellular Vesicles in Females With Alzheimer's Disease Compared to Males.
Erxian decoction inhibits apoptosis by activating Akt1 and repairs spinal cord injury in rats.
Tumor Microenvironment and Immune Escape in the Time Course of Glioblastoma.
An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation.
Neutrophil Nanovesicle Protects against Experimental Autoimmune Encephalomyelitis through Enhancing Myelin Clearance by Microglia.
Apelin alleviated neuroinflammation and promoted endogenous neural stem cell proliferation and differentiation after spinal cord injury in rats.
QKI deficiency in macrophages protects mice against JEV infection by regulating cell migration and antiviral response.
Microglia-Specific Expression of HEXA and HEXB Leads to Poor Prognosis in Glioblastoma Patients.
TMEM119 facilitates ovarian cancer cell proliferation, invasion, and migration via the PDGFRB/PI3K/AKT signaling pathway.
Can quantifying morphology and TMEM119 expression distinguish between microglia and infiltrating macrophages after ischemic stroke and reperfusion in male and female mice?
Flow cytometry analysis of immune and glial cells in a trigeminal neuralgia rat model.
Age and sex differences in primary microglia culture: A comparative study.
Methane-Rich Saline Alleviates CA/CPR Brain Injury by Inhibiting Oxidative Stress, Microglial Activation-Induced Inflammatory Responses, and ER Stress-Mediated Apoptosis.
Electroacupuncture Treatment Attenuates Paclitaxel-Induced Neuropathic Pain in Rats via Inhibiting Spinal Glia and the TLR4/NF-κB Pathway.
Contribution of the P2X4 Receptor in Rat Hippocampus to the Comorbidity of Chronic Pain and Depression.
Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake.
Zhang G, Lu J, Zheng J, Mei S, Li H, Zhang X, Ping A, Gao S, Fang Y, Yu J
Neural regeneration research 2024 Jan;19(1):161-170
Neural regeneration research 2024 Jan;19(1):161-170
Panax quinquefolium saponins attenuates microglia activation following acute cerebral ischemia-reperfusion injury via Nrf2/miR-103-3p/TANK pathway.
Bai X, Qiu Y, Wang J, Dong Y, Zhang T, Jin H
Cell biology international 2024 Feb;48(2):201-215
Cell biology international 2024 Feb;48(2):201-215
TNF-α Levels Are Increased in Patients with Subjective Cognitive Impairment and Are Negatively Correlated with β Amyloid-42.
Serafini S, Ferretti G, Monterosso P, Angiolillo A, Di Costanzo A, Matrone C
Antioxidants (Basel, Switzerland) 2024 Feb 8;13(2)
Antioxidants (Basel, Switzerland) 2024 Feb 8;13(2)
TMEM119 (c.G143A, p.S48L) Mutation Is Involved in Primary Failure of Eruption by Attenuating Glycolysis-Mediated Osteogenesis.
Xu M, Wang D, Li K, Ma T, Wang Y, Xia B
International journal of molecular sciences 2024 Feb 29;25(5)
International journal of molecular sciences 2024 Feb 29;25(5)
Prebiotic diet normalizes aberrant immune and behavioral phenotypes in a mouse model of autism spectrum disorder.
Prince N, Peralta Marzal LN, Markidi A, Ahmed S, Adolfs Y, Pasterkamp RJ, Kumar H, Roeselers G, Garssen J, Kraneveld AD, Perez-Pardo P
Acta pharmacologica Sinica 2024 Aug;45(8):1591-1603
Acta pharmacologica Sinica 2024 Aug;45(8):1591-1603
Defective neurite elongation and branching in Nibp/Trappc9 deficient zebrafish and mice.
Hu M, Bodnar B, Zhang Y, Xie F, Li F, Li S, Zhao J, Zhao R, Gedupoori N, Mo Y, Lin L, Li X, Meng W, Yang X, Wang H, Barbe MF, Srinivasan S, Bethea JR, Mo X, Xu H, Hu W
International journal of biological sciences 2023;19(10):3226-3248
International journal of biological sciences 2023;19(10):3226-3248
Primary cilia-mediated regulation of microglial secretion in Alzheimer's disease.
Yeo S, Jang J, Jung HJ, Lee H, Choe Y
Frontiers in molecular biosciences 2023;10:1250335
Frontiers in molecular biosciences 2023;10:1250335
HC067047 Ameliorates Sepsis-associated Encephalopathy by Suppressing Endoplasmic Reticulum Stress and Oxidative Stress-Induced Pyroptosis in the Hippocampi of Mice.
Zhong X, Wang Y, Liu D, Liang Y, Liu W, Huang Y, Xie L, Cao W, Xu Y, Chen L
Neuroscience 2023 May 1;517:117-127
Neuroscience 2023 May 1;517:117-127
Microglial targeted therapy relieves cognitive impairment caused by Cntnap4 deficiency.
Zhang W, Chen H, Ding L, Huang J, Zhang M, Liu Y, Ma R, Zheng S, Gong J, Piña-Crespo JC, Zhang Y
Exploration (Beijing, China) 2023 Jun;3(3):20220160
Exploration (Beijing, China) 2023 Jun;3(3):20220160
Resolvin D1 reprograms energy metabolism to promote microglia to phagocytize neutrophils after ischemic stroke.
Li L, Cheng SQ, Sun YQ, Yu JB, Huang XX, Dong YF, Ji J, Zhang XY, Hu G, Sun XL
Cell reports 2023 Jun 27;42(6):112617
Cell reports 2023 Jun 27;42(6):112617
Plasma derived extracellular vesicle biomarkers of microglia activation in an experimental stroke model.
Roseborough AD, Myers SJ, Khazaee R, Zhu Y, Zhao L, Iorio E, Elahi FM, Pasternak SH, Whitehead SN
Journal of neuroinflammation 2023 Jan 31;20(1):20
Journal of neuroinflammation 2023 Jan 31;20(1):20
Fibrinogen primes the microglial NLRP3 inflammasome and propagates pro-inflammatory signaling via extracellular vesicles: Implications for blood-brain barrier dysfunction.
Roseborough AD, Zhu Y, Zhao L, Laviolette SR, Pasternak SH, Whitehead SN
Neurobiology of disease 2023 Feb;177:106001
Neurobiology of disease 2023 Feb;177:106001
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
Cai W, Hu M, Li C, Wu R, Lu D, Xie C, Zhang W, Li T, Shen S, Huang H, Qiu W, Liu Q, Lu Y, Lu Z
Autophagy 2023 Apr;19(4):1144-1163
Autophagy 2023 Apr;19(4):1144-1163
Differential Effects of APOE Genotype on MicroRNA Cargo of Cerebrospinal Fluid Extracellular Vesicles in Females With Alzheimer's Disease Compared to Males.
Sandau US, McFarland TJ, Smith SJ, Galasko DR, Quinn JF, Saugstad JA
Frontiers in cell and developmental biology 2022;10:864022
Frontiers in cell and developmental biology 2022;10:864022
Erxian decoction inhibits apoptosis by activating Akt1 and repairs spinal cord injury in rats.
Li E, Yan R, Yan K, Huang R, Zhang R, Wen Y, Li S, Li P, Ma Q, Liao B
Heliyon 2022 Nov;8(11):e11279
Heliyon 2022 Nov;8(11):e11279
Tumor Microenvironment and Immune Escape in the Time Course of Glioblastoma.
Virtuoso A, De Luca C, Cirillo G, Riva M, Romano G, Bentivegna A, Lavitrano M, Papa M, Giovannoni R
Molecular neurobiology 2022 Nov;59(11):6857-6873
Molecular neurobiology 2022 Nov;59(11):6857-6873
An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation.
Ferretti G, Romano A, Sirabella R, Serafini S, Maier TJ, Matrone C
Cell & bioscience 2022 Nov 8;12(1):182
Cell & bioscience 2022 Nov 8;12(1):182
Neutrophil Nanovesicle Protects against Experimental Autoimmune Encephalomyelitis through Enhancing Myelin Clearance by Microglia.
Shen S, Cheng X, Zhou L, Zhao Y, Wang H, Zhang J, Sun X, Wang Y, Shu Y, Xu Y, Tao Y, Li M, Lu Z, Cai W, Nie G, Qiu W
ACS nano 2022 Nov 22;16(11):18886-18897
ACS nano 2022 Nov 22;16(11):18886-18897
Apelin alleviated neuroinflammation and promoted endogenous neural stem cell proliferation and differentiation after spinal cord injury in rats.
Liu Q, Zhou S, Wang X, Gu C, Guo Q, Li X, Zhang C, Zhang N, Zhang L, Huang F
Journal of neuroinflammation 2022 Jun 20;19(1):160
Journal of neuroinflammation 2022 Jun 20;19(1):160
QKI deficiency in macrophages protects mice against JEV infection by regulating cell migration and antiviral response.
Deng L, Wang W, Bian P, Wu M, Wang L, Lei Y, Lu Z, Zhai D
Molecular immunology 2022 Aug;148:34-44
Molecular immunology 2022 Aug;148:34-44
Microglia-Specific Expression of HEXA and HEXB Leads to Poor Prognosis in Glioblastoma Patients.
Jia M, Zhang W, Zhu J, Huang C, Zhou J, Lian J, Wang Y, Teng H, Huang Z
Frontiers in oncology 2021;11:685893
Frontiers in oncology 2021;11:685893
TMEM119 facilitates ovarian cancer cell proliferation, invasion, and migration via the PDGFRB/PI3K/AKT signaling pathway.
Sun T, Bi F, Liu Z, Yang Q
Journal of translational medicine 2021 Mar 17;19(1):111
Journal of translational medicine 2021 Mar 17;19(1):111
Can quantifying morphology and TMEM119 expression distinguish between microglia and infiltrating macrophages after ischemic stroke and reperfusion in male and female mice?
Young KF, Gardner R, Sariana V, Whitman SA, Bartlett MJ, Falk T, Morrison HW
Journal of neuroinflammation 2021 Feb 22;18(1):58
Journal of neuroinflammation 2021 Feb 22;18(1):58
Flow cytometry analysis of immune and glial cells in a trigeminal neuralgia rat model.
Lin J, Zhou L, Luo Z, Adam MI, Zhao L, Wang F, Luo D
Scientific reports 2021 Dec 7;11(1):23569
Scientific reports 2021 Dec 7;11(1):23569
Age and sex differences in primary microglia culture: A comparative study.
Ngwa C, Qi S, Mamun AA, Xu Y, Sharmeen R, Liu F
Journal of neuroscience methods 2021 Dec 1;364:109359
Journal of neuroscience methods 2021 Dec 1;364:109359
Methane-Rich Saline Alleviates CA/CPR Brain Injury by Inhibiting Oxidative Stress, Microglial Activation-Induced Inflammatory Responses, and ER Stress-Mediated Apoptosis.
Cui R, Liu S, Wang C, Liu T, Ren J, Jia Y, Tong Y, Liu C, Zhang J
Oxidative medicine and cellular longevity 2020;2020:8829328
Oxidative medicine and cellular longevity 2020;2020:8829328
Electroacupuncture Treatment Attenuates Paclitaxel-Induced Neuropathic Pain in Rats via Inhibiting Spinal Glia and the TLR4/NF-κB Pathway.
Zhao YX, Yao MJ, Liu Q, Xin JJ, Gao JH, Yu XC
Journal of pain research 2020;13:239-250
Journal of pain research 2020;13:239-250
Contribution of the P2X4 Receptor in Rat Hippocampus to the Comorbidity of Chronic Pain and Depression.
Li L, Zou Y, Liu B, Yang R, Yang J, Sun M, Li Z, Xu X, Li G, Liu S, Greffrath W, Treede RD, Li G, Liang S
ACS chemical neuroscience 2020 Dec 16;11(24):4387-4397
ACS chemical neuroscience 2020 Dec 16;11(24):4387-4397
Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake.
Brenna S, Altmeppen HC, Mohammadi B, Rissiek B, Schlink F, Ludewig P, Krisp C, Schlüter H, Failla AV, Schneider C, Glatzel M, Puig B, Magnus T
Journal of extracellular vesicles 2020 Aug 27;9(1):1809065
Journal of extracellular vesicles 2020 Aug 27;9(1):1809065
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