27585-1-AP

antibody from Proteintech Group

Targeting: TMEM119 OBIF

Provider product page for 27585-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [14]
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Product number: 27585-1-AP - Provider product page
Provider: Proteintech Group
Product name: TMEM119 antibody
Antibody type: Polyclonal
Description: TMEM119 antibody (Cat. #27585-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, Mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

TMEM119 protein structure - 27585-1-AP shown in red.

Submitted references IL-6 mediates olfactory dysfunction in a mouse model of allergic rhinitis.

Song XY, Sun Q, Wei SZ, Wang HR, Wang Y, Zhang WB, Ren C, Song XC, Mou YK
Brain research 2024 Jun 15;1833:148885

BMP7 Attenuates Neuroinflammation after Spinal Cord Injury by Suppressing the Microglia Activation and Inducing Microglial Polarization Via the STAT3 Pathway.

Wei X, Huang C, Chen K, Liu S, Wang M, Yang L, Wang Y
Neurochemical research 2023 Sep;48(9):2687-2700

Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Gliomas.

Miller TE, El Farran CA, Couturier CP, Chen Z, D'Antonio JP, Verga J, Villanueva MA, Castro LNG, Tong YE, Saadi TA, Chiocca AN, Fischer DS, Heiland DH, Guerriero JL, Petrecca K, Suva ML, Shalek AK, Bernstein BE
bioRxiv : the preprint server for biology 2023 Oct 27;

CD34(+) cell-derived fibroblast-macrophage cross-talk drives limb ischemia recovery through the OSM-ANGPTL signaling axis.

Song Y, Yang J, Li T, Sun X, Lin R, He Y, Sun K, Han J, Yang G, Li X, Liu B, Yang D, Dang G, Ma X, Du X, Zhang B, Hu Y, Kong W, Wang X, Zhang H, Xu Q, Feng J
Science advances 2023 Apr 14;9(15):eadd2632

Didymin Suppresses Microglia Pyroptosis and Neuroinflammation Through the Asc/Caspase-1/GSDMD Pathway Following Experimental Intracerebral Hemorrhage.

Gu L, Sun M, Li R, Zhang X, Tao Y, Yuan Y, Luo X, Xie Z
Frontiers in immunology 2022;13:810582

Transmembrane protein 119 is neither a specific nor a reliable marker for microglia.

Vankriekelsvenne E, Chrzanowski U, Manzhula K, Greiner T, Wree A, Hawlitschka A, Llovera G, Zhan J, Joost S, Schmitz C, Ponsaerts P, Amor S, Nutma E, Kipp M, Kaddatz H
Glia 2022 Jun;70(6):1170-1190

Single-cell analysis of human basal cell carcinoma reveals novel regulators of tumor growth and the tumor microenvironment.

Guerrero-Juarez CF, Lee GH, Liu Y, Wang S, Karikomi M, Sha Y, Chow RY, Nguyen TTL, Iglesias VS, Aasi S, Drummond ML, Nie Q, Sarin K, Atwood SX
Science advances 2022 Jun 10;8(23):eabm7981

A modified high-yield method for primary culture of rat retinal microglial cells.

Han X, Liu X, Zhuang J, Liang X, Luo Q, Chen P, Wen Y, Wang X, Peng J, Yang Y, Sha X, Zhuang J
Experimental eye research 2022 Feb;215:108919

Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer's disease.

Dong Y, Yu H, Li X, Bian K, Zheng Y, Dai M, Feng X, Sun Y, He Y, Yu B, Zhang H, Wu J, Yu X, Wu H, Kong W
Journal of neuroinflammation 2022 Aug 15;19(1):205

Validation of Induced Microglia-Like Cells (iMG Cells) for Future Studies of Brain Diseases.

Banerjee A, Lu Y, Do K, Mize T, Wu X, Chen X, Chen J
Frontiers in cellular neuroscience 2021;15:629279

P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression.

Yeini E, Ofek P, Pozzi S, Albeck N, Ben-Shushan D, Tiram G, Golan S, Kleiner R, Sheinin R, Israeli Dangoor S, Reich-Zeliger S, Grossman R, Ram Z, Brem H, Hyde TM, Magod P, Friedmann-Morvinski D, Madi A, Satchi-Fainaro R
Nature communications 2021 Mar 26;12(1):1912

MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.

Xin D, Li T, Chu X, Ke H, Liu D, Wang Z
Pharmacological research 2021 Feb;164:105322

Toll-like receptor-9 (TLR-9) deficiency alleviates optic nerve injury (ONI) by inhibiting inflammatory response in vivo and in vitro.

Zhang L, Li X
Experimental cell research 2020 Nov 1;396(1):112159

Early Histone Deacetylase Inhibition Mitigates Ischemia/Reperfusion Brain Injury by Reducing Microglia Activation and Modulating Their Phenotype.

Li S, Lu X, Shao Q, Chen Z, Huang Q, Jiao Z, Huang X, Yue M, Peng J, Zhou X, Chao D, Zhao H, Ji J, Ji Y, Ji Q
Frontiers in neurology 2019;10:893

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