Antibody data
- Antibody Data
- Antigen structure
- References [27]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 27585-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- TMEM119 antibody
- Antibody type
- Polyclonal
- Description
- TMEM119 antibody (Cat. #27585-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, Mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Probiotic Spore-Based Oral Biotherapeutics Promote Brain Targeting toward Gut-Brain Dual-Regulation for Parkinson's Disease Treatment.
Changes in the microglial phenotype drive neuroinflammation independent of systemic inflammation in the acute stage of heatstroke.
Integrative analysis of single-cell and bulk transcriptome data reveals age-related immune cell alterations in primary glioblastoma associated with prognosis.
Attenuation of Blood-Brain Barrier Disruption in Traumatic Brain Injury via Inhibition of NKCC1 Cotransporter: Insights into the NF-κB/NLRP3 Signaling Pathway.
Expression of anti-amyloid CARs in microglia promotes efficient and selective phagocytosis of Aβ1‒42.
CXCL1-CXCR2 signaling mediates the activation of microglia in the nucleus tractus solitarii to promote pancreatic cancer-induced pain.
GSDME-mediated pyroptosis in microglia exacerbates demyelination and neuroinflammation in multiple sclerosis: insights from humans and cuprizone-induced demyelination model mice.
Deacetylase SIRT2 Inhibition Promotes Microglial M2 Polarization Through Axl/PI3K/AKT to Alleviate White Matter Injury After Subarachnoid Hemorrhage.
Extracellular Vesicle-Liposome-Darunavir Formulation for the Treatment of HIV Neuropathogenesis.
Esketamine improves cognitive function in sepsis-associated encephalopathy by inhibiting microglia-mediated neuroinflammation.
IL-6 mediates olfactory dysfunction in a mouse model of allergic rhinitis.
miR-223 accelerates lipid droplets clearance in microglia following spinal cord injury by upregulating ABCA1.
Artificial Microglia Nanoplatform Loaded With Anti-RGMa in Acoustic/Magnetic Feld for Recanalization and Neuroprotection in Acute Ischemic Stroke.
Tetramerization of PKM2 Alleviates Traumatic Brain Injury by Ameliorating Mitochondrial Damage in Microglia.
BMP7 Attenuates Neuroinflammation after Spinal Cord Injury by Suppressing the Microglia Activation and Inducing Microglial Polarization Via the STAT3 Pathway.
Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Gliomas.
CD34(+) cell-derived fibroblast-macrophage cross-talk drives limb ischemia recovery through the OSM-ANGPTL signaling axis.
Didymin Suppresses Microglia Pyroptosis and Neuroinflammation Through the Asc/Caspase-1/GSDMD Pathway Following Experimental Intracerebral Hemorrhage.
Transmembrane protein 119 is neither a specific nor a reliable marker for microglia.
Single-cell analysis of human basal cell carcinoma reveals novel regulators of tumor growth and the tumor microenvironment.
A modified high-yield method for primary culture of rat retinal microglial cells.
Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer's disease.
Validation of Induced Microglia-Like Cells (iMG Cells) for Future Studies of Brain Diseases.
P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression.
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
Toll-like receptor-9 (TLR-9) deficiency alleviates optic nerve injury (ONI) by inhibiting inflammatory response in vivo and in vitro.
Early Histone Deacetylase Inhibition Mitigates Ischemia/Reperfusion Brain Injury by Reducing Microglia Activation and Modulating Their Phenotype.
Feng Q, Li Y, Sun L, Zhang J, Shou L, Zhu J, Zhou H, Si B, Gu X, Du C, Zhang Z, Wang L
ACS nano 2026 Mar 10;20(9):7518-7533
ACS nano 2026 Mar 10;20(9):7518-7533
Changes in the microglial phenotype drive neuroinflammation independent of systemic inflammation in the acute stage of heatstroke.
Li P, Wang Z, Liu J, Wang G, Luo X, Luo Z, Shen T, He G, Yang X
iScience 2026 Apr 17;29(4):115254
iScience 2026 Apr 17;29(4):115254
Integrative analysis of single-cell and bulk transcriptome data reveals age-related immune cell alterations in primary glioblastoma associated with prognosis.
Jing Z, Qiu B, Ai C, Wang C, Wang X, Li B, Hou L, Yin B, Han W, Peng X
Cancer immunology, immunotherapy : CII 2025 Nov 12;74(12):368
Cancer immunology, immunotherapy : CII 2025 Nov 12;74(12):368
Attenuation of Blood-Brain Barrier Disruption in Traumatic Brain Injury via Inhibition of NKCC1 Cotransporter: Insights into the NF-κB/NLRP3 Signaling Pathway.
Zhang Z, Wang H, Tao B, Shi X, Chen G, Ma H, Peng R, Zhang J
Journal of neurotrauma 2025 May;42(9-10):814-831
Journal of neurotrauma 2025 May;42(9-10):814-831
Expression of anti-amyloid CARs in microglia promotes efficient and selective phagocytosis of Aβ1‒42.
Heiss CN, Riise R, Hanse E, Fruhwürth S, Zetterberg H, Björefeldt A
Gene therapy 2025 Jul;32(4):333-338
Gene therapy 2025 Jul;32(4):333-338
CXCL1-CXCR2 signaling mediates the activation of microglia in the nucleus tractus solitarii to promote pancreatic cancer-induced pain.
Chen K, Ye Q, Zhang Y, Qi Z, Huang Y, Lu W, Wang X, Wang Y, Cao L, Qiu S, Xu Y, Huang J, Xie J
Brain, behavior, and immunity 2025 Jan;123:1026-1041
Brain, behavior, and immunity 2025 Jan;123:1026-1041
GSDME-mediated pyroptosis in microglia exacerbates demyelination and neuroinflammation in multiple sclerosis: insights from humans and cuprizone-induced demyelination model mice.
Wang D, Zhang T, Shao Q, Wu X, Zhao X, Zhang H, Wang Y, Sun J, Chang X, Zhu K, Wu S, Cao L, Chen W, Wang J
Cell death and differentiation 2025 Dec;32(12):2368-2383
Cell death and differentiation 2025 Dec;32(12):2368-2383
Deacetylase SIRT2 Inhibition Promotes Microglial M2 Polarization Through Axl/PI3K/AKT to Alleviate White Matter Injury After Subarachnoid Hemorrhage.
Yuan K, Wu Q, Yao Y, Shao J, Zhu S, Yang J, Sun Q, Zhao J, Xu J, Wu P, Li Y, Shi H
Translational stroke research 2025 Aug;16(4):1075-1093
Translational stroke research 2025 Aug;16(4):1075-1093
Extracellular Vesicle-Liposome-Darunavir Formulation for the Treatment of HIV Neuropathogenesis.
Zhou L, Godse S, Sinha N, Ma D, Mirzahosseini G, Salman M, Pulliam P, Tan C, Singh UP, Ishrat T, Kochat H, Kumar S
ACS applied nano materials 2025 Apr 11;8(14):6857-6876
ACS applied nano materials 2025 Apr 11;8(14):6857-6876
Esketamine improves cognitive function in sepsis-associated encephalopathy by inhibiting microglia-mediated neuroinflammation.
Li H, Hu W, Wu Z, Tian B, Ren Y, Zou X
European journal of pharmacology 2024 Nov 15;983:177014
European journal of pharmacology 2024 Nov 15;983:177014
IL-6 mediates olfactory dysfunction in a mouse model of allergic rhinitis.
Song XY, Sun Q, Wei SZ, Wang HR, Wang Y, Zhang WB, Ren C, Song XC, Mou YK
Brain research 2024 Jun 15;1833:148885
Brain research 2024 Jun 15;1833:148885
miR-223 accelerates lipid droplets clearance in microglia following spinal cord injury by upregulating ABCA1.
Ou Z, Cheng Y, Ma H, Chen K, Lin Q, Chen J, Guo R, Huang Z, Cheng Q, Alaeiilkhchi N, Zhu Q, Huang Z, Jiang H
Journal of translational medicine 2024 Jul 15;22(1):659
Journal of translational medicine 2024 Jul 15;22(1):659
Artificial Microglia Nanoplatform Loaded With Anti-RGMa in Acoustic/Magnetic Feld for Recanalization and Neuroprotection in Acute Ischemic Stroke.
Cheng R, Luo X, Wu X, Wang Z, Chen Z, Zhang S, Xiao H, Zhong J, Zhang R, Cao Y, Qin X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2410529
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2410529
Tetramerization of PKM2 Alleviates Traumatic Brain Injury by Ameliorating Mitochondrial Damage in Microglia.
Zhu H, Zhang H, Zhao XJ, Zhang L, Liu X, Zhang ZY, Ren YZ, Feng Y
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 Aug 28;19(1):48
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2024 Aug 28;19(1):48
BMP7 Attenuates Neuroinflammation after Spinal Cord Injury by Suppressing the Microglia Activation and Inducing Microglial Polarization Via the STAT3 Pathway.
Wei X, Huang C, Chen K, Liu S, Wang M, Yang L, Wang Y
Neurochemical research 2023 Sep;48(9):2687-2700
Neurochemical research 2023 Sep;48(9):2687-2700
Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Gliomas.
Miller TE, El Farran CA, Couturier CP, Chen Z, D'Antonio JP, Verga J, Villanueva MA, Castro LNG, Tong YE, Saadi TA, Chiocca AN, Fischer DS, Heiland DH, Guerriero JL, Petrecca K, Suva ML, Shalek AK, Bernstein BE
bioRxiv : the preprint server for biology 2023 Oct 27;
bioRxiv : the preprint server for biology 2023 Oct 27;
CD34(+) cell-derived fibroblast-macrophage cross-talk drives limb ischemia recovery through the OSM-ANGPTL signaling axis.
Song Y, Yang J, Li T, Sun X, Lin R, He Y, Sun K, Han J, Yang G, Li X, Liu B, Yang D, Dang G, Ma X, Du X, Zhang B, Hu Y, Kong W, Wang X, Zhang H, Xu Q, Feng J
Science advances 2023 Apr 14;9(15):eadd2632
Science advances 2023 Apr 14;9(15):eadd2632
Didymin Suppresses Microglia Pyroptosis and Neuroinflammation Through the Asc/Caspase-1/GSDMD Pathway Following Experimental Intracerebral Hemorrhage.
Gu L, Sun M, Li R, Zhang X, Tao Y, Yuan Y, Luo X, Xie Z
Frontiers in immunology 2022;13:810582
Frontiers in immunology 2022;13:810582
Transmembrane protein 119 is neither a specific nor a reliable marker for microglia.
Vankriekelsvenne E, Chrzanowski U, Manzhula K, Greiner T, Wree A, Hawlitschka A, Llovera G, Zhan J, Joost S, Schmitz C, Ponsaerts P, Amor S, Nutma E, Kipp M, Kaddatz H
Glia 2022 Jun;70(6):1170-1190
Glia 2022 Jun;70(6):1170-1190
Single-cell analysis of human basal cell carcinoma reveals novel regulators of tumor growth and the tumor microenvironment.
Guerrero-Juarez CF, Lee GH, Liu Y, Wang S, Karikomi M, Sha Y, Chow RY, Nguyen TTL, Iglesias VS, Aasi S, Drummond ML, Nie Q, Sarin K, Atwood SX
Science advances 2022 Jun 10;8(23):eabm7981
Science advances 2022 Jun 10;8(23):eabm7981
A modified high-yield method for primary culture of rat retinal microglial cells.
Han X, Liu X, Zhuang J, Liang X, Luo Q, Chen P, Wen Y, Wang X, Peng J, Yang Y, Sha X, Zhuang J
Experimental eye research 2022 Feb;215:108919
Experimental eye research 2022 Feb;215:108919
Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer's disease.
Dong Y, Yu H, Li X, Bian K, Zheng Y, Dai M, Feng X, Sun Y, He Y, Yu B, Zhang H, Wu J, Yu X, Wu H, Kong W
Journal of neuroinflammation 2022 Aug 15;19(1):205
Journal of neuroinflammation 2022 Aug 15;19(1):205
Validation of Induced Microglia-Like Cells (iMG Cells) for Future Studies of Brain Diseases.
Banerjee A, Lu Y, Do K, Mize T, Wu X, Chen X, Chen J
Frontiers in cellular neuroscience 2021;15:629279
Frontiers in cellular neuroscience 2021;15:629279
P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression.
Yeini E, Ofek P, Pozzi S, Albeck N, Ben-Shushan D, Tiram G, Golan S, Kleiner R, Sheinin R, Israeli Dangoor S, Reich-Zeliger S, Grossman R, Ram Z, Brem H, Hyde TM, Magod P, Friedmann-Morvinski D, Madi A, Satchi-Fainaro R
Nature communications 2021 Mar 26;12(1):1912
Nature communications 2021 Mar 26;12(1):1912
MSCs-extracellular vesicles attenuated neuroinflammation, synapse damage and microglial phagocytosis after hypoxia-ischemia injury by preventing osteopontin expression.
Xin D, Li T, Chu X, Ke H, Liu D, Wang Z
Pharmacological research 2021 Feb;164:105322
Pharmacological research 2021 Feb;164:105322
Toll-like receptor-9 (TLR-9) deficiency alleviates optic nerve injury (ONI) by inhibiting inflammatory response in vivo and in vitro.
Zhang L, Li X
Experimental cell research 2020 Nov 1;396(1):112159
Experimental cell research 2020 Nov 1;396(1):112159
Early Histone Deacetylase Inhibition Mitigates Ischemia/Reperfusion Brain Injury by Reducing Microglia Activation and Modulating Their Phenotype.
Li S, Lu X, Shao Q, Chen Z, Huang Q, Jiao Z, Huang X, Yue M, Peng J, Zhou X, Chao D, Zhao H, Ji J, Ji Y, Ji Q
Frontiers in neurology 2019;10:893
Frontiers in neurology 2019;10:893
No comments: Submit comment
No validations: Submit validation data