Antibody data
- Antibody Data
- Antigen structure
- References [75]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
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- Product number
- 18309-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18309-1-AP, RRID:AB_2128759
- Product name
- Integrin Beta 3 antibody
- Antibody type
- Polyclonal
- Description
- Integrin Beta 3 antibody (Cat. #18309-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Stem cell therapy targets THBS1 to reverse endometrial fibrosis.
Crebanine protects against ovariectomy-induced bone loss by targeting Sirt1 to interfere with NF-κB acetylation and ROS activity.
An integrated network pharmacology and proteomics approach reveals the anti-fibrotic effect of Fushen Granule on peritoneal fibrosis.
AIBP deficiency drives MAFLD advancement via ITGβ3 mediated lipid metabolism disruption and pro-inflammatory activation.
Therapeutic Targeting of the IRF9/RTN4/RHOA/ROCK Pathway via RVG29-Modified PLGA Nanoparticles and rTMS for Neural and Vascular Regeneration Post-Cerebral Infarction.
Role of Periostin in the Development of Nasal Hyperresponsiveness in Mice with Allergic Rhinitis.
Periostin drives rheumatoid arthritis progression by regulating integrin αvβ3-mediated transforming growth factor-β1/SMAD signaling.
Chiral Fe(3)O(4)/GelMA hydrogels regulate the osteoimmune microenvironment via Itgb3-mediated macrophage polarization to combat peri-implantitis.
Integrin β3-mediated platelet extracellular vesicle adhesion facilitates vascular smooth muscle cell dysfunction in postinjury intimal hyperplasia.
Synergistic exacerbation of periprosthetic osteolysis by inflammatory bowel disease and titanium ions: Impaired osteogenesis of BMSCs via PI3K/AKT signaling.
Hybrid cell membrane coating orchestrates foreign-body reactions, anti-adhesion, and pro-regeneration in abdominal wall reconstruction.
Ozone aging amplifies the tumor-promoting effects associated with low-dose graphene oxide exposure in bladder tumors via the integrin αV signaling pathway.
Inflammation-responsive biomimetic nanoparticles with epigallocatechin-3-gallate for acute lung injury therapy via autophagy enhancement.
Engineered platelets-based nano-aircraft system for precise tumor chemo-immunotherapy with graded drug delivery and self-recognized tumor targeting.
Pharmacological effects and mechanism of Ilexsaponin A1 in modulating platelet function.
Integrin β3 N125 glycosylation is essential for human cytomegalovirus entry into fibroblasts.
Platelet Membrane-Coated Drug-Loaded Nanoparticles for Dual-Modal Imaging and Photodynamic Therapy in Triple-Negative Breast Cancer.
Calpain-2-Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection.
Developmental exposure to perfluorooctane sulfonate(PFOS) impairs the endometrial receptivity.
Crucial roles of asprosin in cisplatin-induced ferroptosis and acute kidney injury.
Sofalcone inhibits osteoclastogenesis through Keap1/Nrf2 signaling activation and mitigates ovariectomy-induced bone loss.
High-Throughput Proteomics and Immunohistochemistry of Orbital Connective Tissue in Graves' Orbitopathy.
A Study on Regulating OSCC Cell Function by Blocking Integrin αvβ3 With Cilengitide.
Ultrasound-actuated platelet mimetic nanomotors enable targeted piezocatalytic ROS storm for precision thrombolysis.
Small molecule BLVRB redox inhibitor promotes megakaryocytopoiesis and stress thrombopoiesis in vivo.
Platelets camouflaged nanovehicle improved bladder cancer immunotherapy by triggering pyroptosis.
Matricellular protein CCN1 promotes collagen alignment and scar integrity after myocardial infarction.
Hepatocyte growth factor promotes melanoma metastasis through ubiquitin-specific peptidase 22-mediated integrins upregulation.
Excessive proliferating cell nuclear antigen attenuates endometrial adhesive capacity and decidualization in patients with recurrent implantation failure.
VSIG4 inhibits RANKL-induced osteoclastogenesis by enhancing Nrf2-dependent antioxidant response against reactive oxygen species production.
Nicotine regulates abnormal macrophage polarization and trophoblast invasion associated with preterm labor via the α7nAChR/SIRT1 axis.
Human Seminal Extracellular Vesicles Enhance Endometrial Receptivity Through Leukemia Inhibitory Factor.
SLC44A2 regulates vascular smooth muscle cell phenotypic switching and aortic aneurysm.
PEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3.
Decreased FoxO1 expression contributes to facet joint osteoarthritis pathogenesis by impairing chondrocyte migration and extracellular matrix synthesis.
Atp6v1h Deficiency Blocks Bone Loss in Simulated Microgravity Mice through the Fos-Jun-Src-Integrin Pathway.
hUC-MSCs-derived MFGE8 ameliorates locomotor dysfunction via inhibition of ITGB3/ NF-κB signaling in an NMO mouse model.
Bruceine B Displays Potent Antimyeloma Activity by Inducing the Degradation of the Transcription Factor c-Maf.
Pec 1 of Pseudomonas aeruginosa Inhibits Bacterial Clearance of Host by Blocking Autophagy in Macrophages.
Enhancer of zeste homolog 2 facilitates phenotypic transition of vascular smooth muscle cells leading to aortic aneurysm/dissection.
Enhancing endometrial receptivity: the roles of human chorionic gonadotropin in autophagy and apoptosis regulation in endometrial stromal cells.
Cleavage of periostin by MMP9 protects mice from kidney cystic disease.
Glycosylation-Engineered Platelet Membrane-Coated Interleukin 10 Nanoparticles for Targeted Inhibition of Vascular Restenosis.
Repurposing of rilpivirine for preventing platelet β3 integrin-dependent thrombosis by targeting c-Src active autophosphorylation.
ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3.
Proteomic Characterization of Peritoneal Extracellular Vesicles in a Mouse Model of Peritoneal Fibrosis.
The Expression of αvβ3 and Osteopontin in Osteoarthritic Knee Cartilage and Their Correlations With Disease Severity and Chondrocyte Senescence.
Deposition of platelet-derived microparticles in podocytes contributes to diabetic nephropathy.
Integrin β(3) directly inhibits the Gα(13)-p115RhoGEF interaction to regulate G protein signaling and platelet exocytosis.
JP1, a polypeptide specifically targeting integrin αVβ3, ameliorates choroidal neovascularization and diabetic retinopathy in mice.
Platelet membrane-camouflaged nanoparticles carry microRNA inhibitor against myocardial ischaemia‒reperfusion injury.
Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer.
ELMO1 Regulates RANKL-Stimulated Differentiation and Bone Resorption of Osteoclasts.
A blood circulation-prolonging peptide anchored biomimetic phage-platelet hybrid nanoparticle system for prolonged blood circulation and optimized anti-bacterial performance.
Construction and evaluation of novel αvβ3 integrin ligand-conjugated ultrasmall star polymer micelles targeted glomerular podocytes through GFB permeation.
Biomimetic Platform Based on Mesoporous Platinum for Multisynergistic Cancer Therapy.
DMAG, a novel countermeasure for the treatment of thrombocytopenia.
Targeting Gα(13)-integrin interaction ameliorates systemic inflammation.
A comprehensive genome-wide analysis of long non-coding RNA and mRNA expression profiles of JAK2V617F-positive classical myeloproliferative neoplasms.
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Integrin β3-mediated platelet extracellular vesicle adhesion facilitates vascular smooth muscle cell dysfunction in postinjury intimal hyperplasia.
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Biology open 2019 May 13;8(5)
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Journal of tissue engineering and regenerative medicine 2018 May;12(5):1209-1219
Journal of tissue engineering and regenerative medicine 2018 May;12(5):1209-1219
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Fenofibrate Exerts Protective Effects in Diabetic Retinopathy via Inhibition of the ANGPTL3 Pathway.
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Cell proliferation 2017 Jun;50(3)
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Nanotechnology 2014 Jun 27;25(25):255102
Nanotechnology 2014 Jun 27;25(25):255102
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human placenta tissue were subjected to SDS PAGE followed by western blot with 18309-1-AP(ITGB3 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 18309-1-AP(ITGB3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The Integrin beta-3 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human Integrin beta-3. This antibody recognizes human,mouse,rat antigen. The Integrin beta-3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.