336403

ITGB3 antibody from BioLegend
CD61, GP3A, GPIIIa

Antibody data

Product number
336403
Provider
BioLegend
Proper citation
BioLegend Cat#336403, RRID:AB_1227581
Product name
FITC anti-human CD61
Provider product page
BioLegend - 336403
Antibody type
Monoclonal
Antigen
CD61
Description
CD61, known as integrin b3 or glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of integrin family that associates with platelet gpIIb (CD41) forming CD41/CD61 complex and associates with integrin aV (CD51) forming aV/b3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblast, macrophages and some tumor cells, involved in tumor metastasis and in adenovirus infection through binding to RGD motif ECM proteins.
Reactivity
Human
Host
Mouse
Conjugate
Green dye
Isotype
IgG
Vial size
25 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Provider Type Product Number
- No reagents -