336403

antibody from BioLegend

Targeting: ITGB3 CD61, GP3A, GPIIIa

Antibody data

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Validation data

Product number: 336403 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#336403, RRID:AB_1227581
Product name: FITC anti-human CD61
Antibody type: Monoclonal
Antigen: CD61
Description: CD61, known as integrin b3 or glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of integrin family that associates with platelet gpIIb (CD41) forming CD41/CD61 complex and associates with integrin aV (CD51) forming aV/b3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblast, macrophages and some tumor cells, involved in tumor metastasis and in adenovirus infection through binding to RGD motif ECM proteins.
Reactivity: Human
Host: Mouse
Conjugate: Green dye
Isotype: IgG
Vial size: 25 tests
Storage: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

ITGB3 protein structure - 336403 shown in red.