Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- PA1627 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Integrin beta 3/ITGB3 Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for CD61/ITGB3 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB, IHC-P, FCM. Reactive species: Human. CD61/ITGB3 information: Molecular Weight: 87058 MW; Subcellular Localization: Cell membrane ; Single- pass type I membrane protein . Cell projection, lamellipodium membrane . Cell junction, focal adhesion ; Tissue Specificity: Isoform beta-3A and isoform beta-3C are widely expressed. Isoform beta-3A is specifically expressed in osteoblast cells; isoform beta-3C is specifically expressed in prostate and testis.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references TGFβ3-mediated induction of Periostin facilitates head and neck cancer growth and is associated with metastasis.
Study on the expression and clinical significances of lewis y antigen and integrin αv, β3 in epithelial ovarian tumors.
Overexpression of Lewis(y) antigen protects ovarian cancer RMG-1 cells from carboplatin-induced apoptosis by the upregulation of Topo-I and Topo-II β.
Qin X, Yan M, Zhang J, Wang X, Shen Z, Lv Z, Li Z, Wei W, Chen W
Scientific reports 2016 Feb 9;6:20587
Scientific reports 2016 Feb 9;6:20587
Study on the expression and clinical significances of lewis y antigen and integrin αv, β3 in epithelial ovarian tumors.
Wang Y, Liu J, Lin B, Wang C, Li Q, Liu S, Yan L, Zhang S, Iwamori M
International journal of molecular sciences 2011;12(6):3409-21
International journal of molecular sciences 2011;12(6):3409-21
Overexpression of Lewis(y) antigen protects ovarian cancer RMG-1 cells from carboplatin-induced apoptosis by the upregulation of Topo-I and Topo-II β.
Wang C, Yan L, Wang Y, Lin B, Liu S, Li Q, Gao L, Zhang S, Iwamori M
Anatomical record (Hoboken, N.J. : 2007) 2011 Jun;294(6):961-9
Anatomical record (Hoboken, N.J. : 2007) 2011 Jun;294(6):961-9
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti-Integrin beta 3 antibody, PA1627, Western blottingLane 1: JURKAT Cell LysateLane 2: RAJI Cell LysateLane 3: CEM Cell LysateLane 4: COLO320 Cell Lysate
- Additional image