APR06843G

antibody from Leading Biology

Targeting: SOGA1 C20orf117, dJ132F21.1, FLJ44670, KIAA0889, SOGA

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

APR06843G

Provider

Leading Biology

Product name

SOGA1 Antibody

Antibody type

Polyclonal

Description

The recently identified protein suppressor of glucose by autophagy protein 1 (SOGA1) has been found to be involved in the regulation of autophagy (1). SOGA1 is thought to contribute to adiponectin-mediated insulin-dependent inhibition of autophagy during the activation of adenosine monophosphate kinase (AMPK) (1,2). SOGA1 contains an internal signal peptide that enables the secretion of a circulating fragment of SOGA1, providing a surrogate marker for intracellular SOGA1 levels (2). Knockdown of SOGA1 elevated glucose production in primary hepatocytes indicates that SOGA1 is an inhibitor of glucose production. It thus might be useful as a novel therapeutic target for diabetes (3).

Reactivity

Human

Host

Rabbit

Isotype

IgG

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.